Apoptosis induced by emodin is associated with alterations of intracellular acidification and reactive oxygen species in EC-109 cells

Biochemistry and Cell Biology

Volumn 88, Issue 4, 2010, Pages 767-774

  Wang, Q J ^a   Cai, X B ^a   Liu, M H ^a   Hu, H ^a   Tan, X J ^a   Jing, X B ^a  

^a SHANTOU UNIVERSITY MEDICAL COLLEGE   (China)

Author keywords

Apoptosis; EC 109 cells; Emodin; Intracellular acidification; Reactive oxygen species

Indexed keywords

ANTHRAQUINONE DERIVATIVES; ANTICANCER DRUG; APOPTOSIS; CARCINOMA CELLS; DOSE-DEPENDENT MANNER; ESOPHAGUS CANCER; FLOW CYTOMETRY ANALYSIS; FLUORESCENCE MEASUREMENTS; GROWTH INHIBITION; HEPATOCELLULAR; HERBAL MEDICINES; IN-VITRO; INDUCED APOPTOSIS; INTRACELLULAR PH; LUNG CANCER CELLS; MORPHOLOGICAL CHANGES; REACTIVE OXYGEN SPECIES; TUMOR CELLS;

FLOW CYTOMETRY; KETONES; OXYGEN;

CELL DEATH;

EMODIN; REACTIVE OXYGEN METABOLITE;

ACIDIFICATION; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CELL PH; CONTROLLED STUDY; ESOPHAGUS CARCINOMA; HUMAN; HUMAN CELL; TUMOR GROWTH;

ACIDS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CARCINOMA; CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; EMODIN; ESOPHAGEAL NEOPLASMS; FLOW CYTOMETRY; HUMANS; HYDROGEN-ION CONCENTRATION; INTRACELLULAR FLUID; REACTIVE OXYGEN SPECIES; UP-REGULATION;

EID: 77954925622     PISSN: 08298211     EISSN: 12086002     Source Type: Journal    
DOI: 10.1139/O10-020     Document Type: Article

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