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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 1, 2012, Pages 323-326

Emodin inhibits migration and invasion of DLD-1 (PRL-3) cells via inhibition of PRL-3 phosphatase activity

(7) Han, Young Min a,b Lee, Su Kyung a Jeong, Dae Gwin a Ryu, Seong Eon a Han, Dong Cho a,b Kim, Dae Keun c Kwon, Byoung Mog a,b

a Korea Research Institute of Bioscience and Biotechnology (KRIBB) (South Korea)

b University of Science and Technology (UST) (South Korea)

c Woosuk University (South Korea)

Author keywords

Emodin; Invasion; Metastasis; Migration; PRL 3

Indexed keywords

ANTIMETASTATIC AGENT; EMODIN; EZRIN; PHOSPHATASE; PRL 3 PHOSPHATASE; UNCLASSIFIED DRUG;

ARTICLE; CANCER INHIBITION; CANCER INVASION; CONTROLLED STUDY; DOSE RESPONSE; DRUG IDENTIFICATION; DRUG POTENCY; DRUG SCREENING; ENZYME INHIBITION; HUMAN; HUMAN TISSUE; IC 50; METASTASIS INHIBITION; PROTEIN PHOSPHORYLATION;

ANTHRAQUINONES; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL MOVEMENT; COLLAGEN; COLONIC NEOPLASMS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; DRUG DESIGN; EMODIN; HUMANS; INHIBITORY CONCENTRATION 50; LAMININ; MODELS, CHEMICAL; NEOPLASM INVASIVENESS; NEOPLASM PROTEINS; NEOPLASMS; PHOSPHORYLATION; PROTEIN TYROSINE PHOSPHATASES; PROTEOGLYCANS;

EID: 84655165080 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2011.11.008 Document Type: Article

Times cited : (31)

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