Emodin, a naturally occurring anthraquinone derivative, suppresses IgE-mediated anaphylactic reaction and mast cell activation

Biochemical Pharmacology

Volumn 82, Issue 11, 2011, Pages 1700-1708

  Lu, Yue ^a   Yang, Ju Hye ^a   Li, Xian ^a   Hwangbo, Kyoung ^a   Hwang, Seung Lark ^a   Taketomi, Yoshitaka ^b   Murakami, Makoto ^b   Chang, Young Chae ^c   Kim, Cheorl Ho ^d   Son, Jong Keun ^a   Chang, Hyeun Wook ^a  

^a Yeungnam University   (South Korea)

^b TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^c The Catholic University of Korea   (South Korea)

^d Sungkyunkwan University   (South Korea)

Author keywords

Emodin; IgE; Mast cells; Passive anaphylactic reaction; Syk kinase

Indexed keywords

EMODIN; FC RECEPTOR; IMMUNOGLOBULIN E; INTERLEUKIN 6; LEUKOTRIENE C4; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROSTAGLANDIN D2; PROTEIN KINASE SYK; TUMOR NECROSIS FACTOR ALPHA;

ANAPHYLAXIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM CELL LEVEL; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE RELEASE; DEGRANULATION; ENZYME PHOSPHORYLATION; MALE; MAST CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANAPHYLAXIS; ANIMALS; ANTI-ALLERGIC AGENTS; CALCIUM; CELL DEGRANULATION; CELLS, CULTURED; EMODIN; ENZYME ACTIVATION; IMMUNOGLOBULIN E; INTERLEUKIN-6; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LEUKOTRIENE C4; MALE; MAST CELLS; MICE; MICE, INBRED BALB C; PASSIVE CUTANEOUS ANAPHYLAXIS; PROSTAGLANDIN D2; PROTEIN-TYROSINE KINASES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 80255123790     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2011.08.022     Document Type: Article

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