-
1
-
-
0036319335
-
Astrocyte-endothelial interactions and blood-brain barrier permeability
-
doi: 10.1046/j.1469-7580.2002.00064.x
-
Abbott, N. J. (2002). Astrocyte-endothelial interactions and blood-brain barrier permeability. J. Anat. 200, 629-638. doi: 10.1046/j.1469-7580.2002.00064.x
-
(2002)
J. Anat
, vol.200
, pp. 629-638
-
-
Abbott, N.J.1
-
2
-
-
70449529433
-
Structure and function of the blood-brain barrier
-
doi: 10.1016/j.nbd.2009.07.030
-
Abbott, N. J., Patabendige, A. A., Dolman, D. E., Yusof, S. R., and Begley, D. J. (2010). Structure and function of the blood-brain barrier. Neurobiol. Dis. 37, 13-25. doi: 10.1016/j.nbd.2009.07.030
-
(2010)
Neurobiol. Dis
, vol.37
, pp. 13-25
-
-
Abbott, N.J.1
Patabendige, A.A.2
Dolman, D.E.3
Yusof, S.R.4
Begley, D.J.5
-
3
-
-
29244463365
-
Astrocyte- endothelial interactions at the blood-brain barrier
-
doi: 10.1038/nrn1824
-
Abbott, N. J., Ronnback, L., and Hansson, E. (2006). Astrocyte- endothelial interactions at the blood-brain barrier. Nat. Rev. Neurosci. 7, 41-53. doi: 10.1038/nrn1824
-
(2006)
Nat. Rev. Neurosci
, vol.7
, pp. 41-53
-
-
Abbott, N.J.1
Ronnback, L.2
Hansson, E.3
-
4
-
-
0028080058
-
Quantitative approaches to delineate paracellular diffusion in cultured epithelial cell monolayers
-
doi: 10.1002/jps.26008 31103
-
Adson, A., Raub, T. J., Burton, P. S., Barsuhn, C. L., Hilgers, A. R., Audus, K. L., et al. (1994). Quantitative approaches to delineate paracellular diffusion in cultured epithelial cell monolayers. J. Pharm. Sci. 83, 1529-1536. doi: 10.1002/jps.26008 31103
-
(1994)
J. Pharm. Sci
, vol.83
, pp. 1529-1536
-
-
Adson, A.1
Raub, T.J.2
Burton, P.S.3
Barsuhn, C.L.4
Hilgers, A.R.5
Audus, K.L.6
-
5
-
-
84971753624
-
Neocortex size, group-size, and the evolution of language
-
doi: 10.1086/204160
-
Aiello, L. C., and Dunbar, R. I. M. (1993). Neocortex size, group-size, and the evolution of language. Curr. Anthropol. 34, 184-193. doi: 10.1086/204160
-
(1993)
Curr. Anthropol
, vol.34
, pp. 184-193
-
-
Aiello, L.C.1
Dunbar, R.I.M.2
-
6
-
-
0003140748
-
The expensive-tissue hypothesis - the brain and the digestive-system in human and primate evolution
-
doi: 10.1086/204350
-
Aiello, L. C., and Wheeler, P. (1995). The expensive-tissue hypothesis - the brain and the digestive-system in human and primate evolution. Curr. Anthropol. 36, 199-221. doi: 10.1086/204350
-
(1995)
Curr. Anthropol
, vol.36
, pp. 199-221
-
-
Aiello, L.C.1
Wheeler, P.2
-
7
-
-
25144476013
-
Spatial and temporal dynamics of the endothelium
-
doi: 10.1111/j.1538-7836.2005.01328.x
-
Aird, W. C. (2005). Spatial and temporal dynamics of the endothelium. J. Thromb. Haemost. 3, 1392-1406. doi: 10.1111/j.1538-7836.2005.01328.x
-
(2005)
J. Thromb. Haemost
, vol.3
, pp. 1392-1406
-
-
Aird, W.C.1
-
8
-
-
33846798106
-
Phenotypic heterogeneity of the endothelium: I. Structure, function, and mechanisms
-
doi: 10.1161/01.RES.0000255691. 76142.4a
-
Aird, W. C. (2007). Phenotypic heterogeneity of the endothelium: I. Structure, function, and mechanisms. Circ. Res. 100, 158-173. doi: 10.1161/01.RES.0000255691. 76142.4a
-
(2007)
Circ. Res
, vol.100
, pp. 158-173
-
-
Aird, W.C.1
-
9
-
-
80051821707
-
Elucidating the mechanobiol-ogy of malignant brain tumors using a brain matrix-mimetic hyaluronic acid hydrogel platform
-
doi: 10.1016/j.biomaterials.2011.07.005
-
Ananthanarayanan, B., Kim, Y., and Kumar, S. (2011). Elucidating the mechanobiol-ogy of malignant brain tumors using a brain matrix-mimetic hyaluronic acid hydrogel platform. Biomaterials 32, 7913-7923. doi: 10.1016/j.biomaterials.2011.07.005
-
(2011)
Biomaterials
, vol.32
, pp. 7913-7923
-
-
Ananthanarayanan, B.1
Kim, Y.2
Kumar, S.3
-
10
-
-
25444463573
-
Endothelial/pericyte interactions
-
doi: 10. 1161/01.RES.0000182903.16652.d7
-
Armulik, A., Abramsson, A., and Betsholtz, C. (2005). Endothelial/pericyte interactions. Circ. Res. 97, 512-523. doi: 10. 1161/01.RES.0000182903.16652.d7
-
(2005)
Circ. Res
, vol.97
, pp. 512-523
-
-
Armulik, A.1
Abramsson, A.2
Betsholtz, C.3
-
11
-
-
78649467527
-
Pericytes regulate the blood-brain barrier
-
doi: 10.1038/nature09522
-
Armulik, A., Genove, G., Mae, M., Nisancioglu, M. H., Wallgard, E., Niaudet, C., et al. (2010). Pericytes regulate the blood-brain barrier. Nature 468, 557-561. doi: 10.1038/nature09522
-
Nature
, vol.468
, pp. 557-561
-
-
Armulik, A.1
Genove, G.2
Mae, M.3
Nisancioglu, M.H.4
Wallgard, E.5
Niaudet, C.6
-
12
-
-
0026321138
-
Cell-cultures as models for drug absorption across the intestinal-mucosa
-
Artursson, P. (1991). Cell-cultures as models for drug absorption across the intestinal-mucosa. Crit. Rev. Ther. Drug Carrier Syst. 8, 305-330.
-
(1991)
Crit. Rev. Ther. Drug Carrier Syst
, vol.8
, pp. 305-330
-
-
Artursson, P.1
-
13
-
-
0035286778
-
Caco-2 monolayers in experimental and theoretical predictions of drug transport
-
. doi: 10.1016/S0169-409X(00)00128-9
-
Artursson, P., Palm, K., and Luthman, K. (2001). Caco-2 monolayers in experimental and theoretical predictions of drug transport. Adv. Drug Deliv. Rev. 46, 27-43. doi: 10.1016/S0169-409X(00)00128-9
-
(2001)
Adv. Drug Deliv. Rev
, vol.46
, pp. 27-43
-
-
Artursson, P.1
Palm, K.2
Luthman, K.3
-
14
-
-
80054958024
-
Concise review: Circulating endothelial progenitor cells for vascular medicine
-
doi: 10.1002/stem.745
-
Asahara, T., Kawamoto, A., and Masuda, H. (2011). Concise review: circulating endothelial progenitor cells for vascular medicine. Stem Cells 29, 1650-1655. doi: 10.1002/stem.745
-
(2011)
Stem Cells
, vol.29
, pp. 1650-1655
-
-
Asahara, T.1
Kawamoto, A.2
Masuda, H.3
-
15
-
-
78149425848
-
Glial and neuronal control of brain blood flow
-
doi: 10.1038/nature09613
-
Attwell, D., Buchan, A. M., Charpak, S., Lauritzen, M., Macvicar, B. A., and Newman, E. A. (2010). Glial and neuronal control of brain blood flow. Nature 468, 232-243. doi: 10.1038/nature09613
-
(2010)
Nature
, vol.468
, pp. 232-243
-
-
Attwell, D.1
Buchan, A.M.2
Charpak, S.3
Lauritzen, M.4
Macvicar, B.A.5
Newman, E.A.6
-
16
-
-
0034784359
-
An energy budget for signaling in the grey matter of the brain
-
doi: 10.1097/00004647-200110000-00001
-
Attwell, D., and Laughlin, S. B. (2001). An energy budget for signaling in the grey matter of the brain. J. Cereb. Blood Flow Metab. 21, 1133-1145. doi: 10.1097/00004647-200110000-00001
-
(2001)
J. Cereb. Blood Flow Metab
, vol.21
, pp. 1133-1145
-
-
Attwell, D.1
Laughlin, S.B.2
-
17
-
-
0022454431
-
Characteristics of the large neutral amino acid transport system of bovine brain microvessel endothelial cell monolayers
-
doi: 10.1111/j.1471-4159.1986.tb04527.x
-
Audus, K. L., and Borchardt, R. T. (1986). Characteristics of the large neutral amino acid transport system of bovine brain microvessel endothelial cell monolayers. J. Neurochem. 47, 484-488. doi: 10.1111/j.1471-4159.1986.tb04527.x
-
(1986)
J. Neurochem
, vol.47
, pp. 484-488
-
-
Audus, K.L.1
Borchardt, R.T.2
-
18
-
-
22544480570
-
A simplified laminin nomenclature
-
doi: 10.1016/j.matbio.2005.05.006
-
Aumailley, M., Bruckner-Tuderman, L., Carter, W. G., Deutzmann, R., Edgar, D., Ekblom, P., et al. (2005) A simplified laminin nomenclature. Matrix Biol. 24, 326-332. doi: 10.1016/j.matbio.2005.05.006
-
(2005)
Matrix Biol
, vol.24
, pp. 326-332
-
-
Aumailley, M.1
Bruckner-Tuderman, L.2
Carter, W.G.3
Deutzmann, R.4
Edgar, D.5
Ekblom, P.6
-
19
-
-
0035468033
-
Physicochemical profiling (solubility, permeability and charge state)
-
doi: 10.2174/1568026013395100
-
Avdeef, A. (2001). Physicochemical profiling (solubility, permeability and charge state). Curr. Top. Med. Chem. 1, 277-351. doi: 10.2174/1568026013395100
-
(2001)
Curr. Top. Med. Chem
, vol.1
, pp. 277-351
-
-
Avdeef, A.1
-
21
-
-
14144250264
-
Caco-2 permeability of weakly basic drugs predicted with the Double-Sink PAMPA method
-
doi: 10.1016/j.ejps.2004.11.011
-
Avdeef, A., Artursson, P., Neuhoff, S., Lazorova, L., Gråsjö, J., and Tavelin, S. (2005). Caco-2 permeability of weakly basic drugs predicted with the Double-Sink PAMPA method. Eur. J. Pharm. Sci. 24, 333-349. doi: 10.1016/j.ejps.2004.11.011
-
(2005)
Eur. J. Pharm. Sci
, vol.24
, pp. 333-349
-
-
Avdeef, A.1
Artursson, P.2
Neuhoff, S.3
Lazorova, L.4
Gråsjö, J.5
Tavelin, S.6
-
22
-
-
33646640645
-
Current industrial practices of assessing permeability and P-glycoprotein interaction
-
doi: 10.1208/aapsj080101
-
Balimane, P. V., Han, Y. H., and Chong, S. H. (2006). Current industrial practices of assessing permeability and P-glycoprotein interaction. AAPS J. 8, E1-E13. doi: 10.1208/aapsj080101
-
(2006)
AAPS J
, vol.8
-
-
Balimane, P.V.1
Han, Y.H.2
Chong, S.H.3
-
23
-
-
0021234697
-
Effects of unstirred layers on membrane phenomena
-
Barry, P. H., and Diamond, J. M. (1984). Effects of unstirred layers on membrane phenomena. Physiol. Rev. 64, 763-872.
-
(1984)
Physiol. Rev
, vol.64
, pp. 763-872
-
-
Barry, P.H.1
Diamond, J.M.2
-
24
-
-
46649085260
-
Decreased blood-brain barrier P-glycoprotein function in the progression of Parkinson's disease, PSP and MSA
-
doi: 10.1007/s00702-008-0030-y
-
Bartels, A. L., Willemsen, A. T., Kortekaas, R., De Jong, B. M., De Vries, R., De Klerk, O., et al. (2008). Decreased blood-brain barrier P-glycoprotein function in the progression of Parkinson's disease, PSP and MSA. J. Neural Transm. 115, 1001-1009. doi: 10.1007/s00702-008-0030-y
-
(2008)
J. Neural Transm
, vol.115
, pp. 1001-1009
-
-
Bartels, A.L.1
Willemsen, A.T.2
Kortekaas, R.3
de Jong, B.M.4
de Vries, R.5
de Klerk, O.6
-
25
-
-
44349163325
-
Coordinated nuclear receptor regulation of the efflux transporter, Mrp2, and the phase-II metabolizing enzyme, GSTpi, at the blood-brain barrier
-
doi: 10.1038/jcbfm.2008.16
-
Bauer, B., Hartz, A. M., Lucking, J. R., Yang, X., Pollack, G. M., and Miller, D. S. (2008). Coordinated nuclear receptor regulation of the efflux transporter, Mrp2, and the phase-II metabolizing enzyme, GSTpi, at the blood-brain barrier. J. Cereb. Blood Flow Metab. 28, 1222-1234. doi: 10.1038/jcbfm.2008.16
-
(2008)
J. Cereb. Blood Flow Metab
, vol.28
, pp. 1222-1234
-
-
Bauer, B.1
Hartz, A.M.2
Lucking, J.R.3
Yang, X.4
Pollack, G.M.5
Miller, D.S.6
-
26
-
-
33847094700
-
Tumor necrosis factor alpha and endothelin-1 increase P-glycoprotein expression and transport activity at the blood-brain barrier
-
doi: 10.1124/mol.106.029512
-
Bauer, B., Hartz, A. M., and Miller, D. S. (2007). Tumor necrosis factor alpha and endothelin-1 increase P-glycoprotein expression and transport activity at the blood-brain barrier. Mol. Pharmacol. 71, 667-675. doi: 10.1124/mol.106.029512
-
(2007)
Mol. Pharmacol
, vol.71
, pp. 667-675
-
-
Bauer, B.1
Hartz, A.M.2
Miller, D.S.3
-
27
-
-
12744253433
-
Modulation of p-glycoprotein transport function at the blood-brain barrier
-
Bauer, B., Hartz, A. M. S., Fricker, G., and Miller, D. S. (2005). Modulation of p-glycoprotein transport function at the blood-brain barrier. Exp. Biol. Med. 230, 118-127.
-
(2005)
Exp. Biol. Med
, vol.230
, pp. 118-127
-
-
Bauer, B.1
Hartz, A.M.S.2
Fricker, G.3
Miller, D.S.4
-
28
-
-
3042590902
-
Endothelial cell-to-cell junctions: Molecular organization and role in vascular homeostasis
-
doi: 10.1152/phys-rev.00035.2003
-
Bazzoni, G., and Dejana, E. (2004). Endothelial cell-to-cell junctions: molecular organization and role in vascular homeostasis. Physiol. Rev. 84, 869-901. doi: 10.1152/phys-rev.00035.2003
-
(2004)
Physiol. Rev
, vol.84
, pp. 869-901
-
-
Bazzoni, G.1
Dejana, E.2
-
29
-
-
0141620181
-
Structural and functional aspects of the blood brain barrier
-
eds L. Prokai and K. Prokai-Tatrai (Basel:Birkhauser Verlag
-
Begley, D. J., and Brightman, M. W. (2003). "Structural and functional aspects of the blood brain barrier," in Progress in Drug Research, eds L. Prokai and K. Prokai-Tatrai (Basel:Birkhauser Verlag), 39-78.
-
(2003)
Progress In Drug Research
, pp. 39-78
-
-
Begley, D.J.1
Brightman, M.W.2
-
30
-
-
0030580410
-
Quantitative evaluation of blood-brain barrier permeability following middle cerebral artery occlusion in rats
-
doi: 10.1016/S0006-8993 (96)00815-3
-
Belayev, L., Busto, R., Zhao, W., and Ginsberg, M. D. (1996). Quantitative evaluation of blood-brain barrier permeability following middle cerebral artery occlusion in rats. Brain Res. 739, 88-96. doi: 10.1016/S0006-8993 (96)00815-3
-
(1996)
Brain Res
, vol.739
, pp. 88-96
-
-
Belayev, L.1
Busto, R.2
Zhao, W.3
Ginsberg, M.D.4
-
31
-
-
78049279739
-
Pericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain aging
-
doi: 10.1016/j.neuron.2010.09.043
-
Bell, R. D., Winkler, E. A., Sagare, A. P., Singh, I., Larue, B., Deane, R., et al. (2010). Pericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain aging. Neuron 68, 409-427. doi: 10.1016/j.neuron.2010.09.043
-
(2010)
Neuron
, vol.68
, pp. 409-427
-
-
Bell, R.D.1
Winkler, E.A.2
Sagare, A.P.3
Singh, I.4
Larue, B.5
Deane, R.6
-
32
-
-
80555157646
-
Circumventricular organs: Receptive and homeostatic functions and clinical implications
-
doi:10.1212/WNL.0b013e31822f04a0
-
Benarroch, E. E. (2011). Circumventricular organs: receptive and homeostatic functions and clinical implications. Neurology 77, 1198-1204. doi:10.1212/WNL.0b013e31822f04a0
-
(2011)
Neurology
, vol.77
, pp. 1198-1204
-
-
Benarroch, E.E.1
-
33
-
-
16344387780
-
The blood brain barrier in HIV infection
-
doi: 10.2741/1427
-
Berger, J. R., and Avison, M. (2004). The blood brain barrier in HIV infection. Front. Biosci. 9, 2680-2685. doi: 10.2741/1427
-
(2004)
Front. Biosci
, vol.9
, pp. 2680-2685
-
-
Berger, J.R.1
Avison, M.2
-
34
-
-
77954288447
-
Establishment of primary cultures of human brain microvascular endothelial cells to provide an in vitro cellular model of the blood-brain barrier
-
doi: 10.1038/nprot.2010.76
-
Bernas, M. J., Cardoso, F. L., Daley, S. K., Weinand, M. E., Campos, A. R., Ferreira, A. J. G., et al. (2010). Establishment of primary cultures of human brain microvascular endothelial cells to provide an in vitro cellular model of the blood-brain barrier. Nat. Protoc. 5, 1265-1272. doi: 10.1038/nprot.2010.76
-
(2010)
Nat. Protoc
, vol.5
, pp. 1265-1272
-
-
Bernas, M.J.1
Cardoso, F.L.2
Daley, S.K.3
Weinand, M.E.4
Campos, A.R.5
Ferreira, A.J.G.6
-
35
-
-
0032913463
-
Increased brain capillaries in chronic hypoxia
-
Boero, J. A., Ascher, J., Arregui, A., Rovainen, C., and Woolsey, T. A. (1999). Increased brain capillaries in chronic hypoxia. J. Appl. Physiol. 86, 1211-1219.
-
(1999)
J. Appl. Physiol
, vol.86
, pp. 1211-1219
-
-
Boero, J.A.1
Ascher, J.2
Arregui, A.3
Rovainen, C.4
Woolsey, T.A.5
-
36
-
-
79958788461
-
The CNS microvascular pericyte: Pericyte-astrocyte crosstalk in the regulation of tissue survival
-
doi: 10.1186/2045-8118-8-8
-
Bonkowski, D., Katyshev, V., Balabanov, R. D., Borisov, A., and Dore-Duffy, P. (2011). The CNS microvascular pericyte: pericyte-astrocyte crosstalk in the regulation of tissue survival. Fluids Barriers CNS 8, 8. doi: 10.1186/2045-8118-8-8
-
(2011)
Fluids Barriers CNS
, vol.8
, pp. 8
-
-
Bonkowski, D.1
Katyshev, V.2
Balabanov, R.D.3
Borisov, A.4
Dore-Duffy, P.5
-
37
-
-
0024450787
-
Metabolic anatomy of brain - a comparison of regional capillary density, glucose-metabolism, and enzyme-activities
-
doi: 10.1002/cne.902880304
-
Borowsky, I. W., and Collins, R. C. (1989a). Metabolic anatomy of brain - a comparison of regional capillary density, glucose-metabolism, and enzyme-activities. J. Comp. Neurol. 288, 401-413. doi: 10.1002/cne.902880304
-
(1989)
J. Comp. Neurol
, vol.288
, pp. 401-413
-
-
Borowsky, I.W.1
Collins, R.C.2
-
38
-
-
0024450787
-
Metabolic anatomy of brain: A comparison of regional capillary density, glucose metabolism, and enzyme activities
-
doi: 10.1002/cne.902880304
-
Borowsky, I. W., and Collins, R. C. (1989b). Metabolic anatomy of brain: a comparison of regional capillary density, glucose metabolism, and enzyme activities. J. Comp. Neurol. 288, 401-413. doi: 10.1002/cne.902880304
-
(1989)
J. Comp. Neurol
, vol.288
, pp. 401-413
-
-
Borowsky, I.W.1
Collins, R.C.2
-
39
-
-
39749132196
-
Blood-brain barrier transport helps to explain discrepancies in in vivo potency between oxycodone and morphine
-
doi: 10.1097/ALN.0b013e318164cf9e
-
Bostrom, E., Hammarlund-Udenaes, M., and Simonsson, U. S. (2008). Blood-brain barrier transport helps to explain discrepancies in in vivo potency between oxycodone and morphine. Anesthesiology 108, 495-505. doi: 10.1097/ALN.0b013e318164cf9e
-
(2008)
Anesthesiology
, vol.108
, pp. 495-505
-
-
Bostrom, E.1
Hammarlund-Udenaes, M.2
Simonsson, U.S.3
-
40
-
-
0034293553
-
Pharmacokinetic-pharmacodynamic modelling of morphine transport across the blood-brain barrier as a cause of the antinociceptive effect delay in rats - a microdialysis study
-
doi: 10.1023/A:1026414713509
-
Bouw, M. R., Gardmark, M., and Hammarlund-Udenaes, M. (2000). Pharmacokinetic-pharmacodynamic modelling of morphine transport across the blood-brain barrier as a cause of the antinociceptive effect delay in rats - a microdialysis study. Pharm. Res. 17, 1220-1227. doi: 10.1023/A:1026414713509
-
(2000)
Pharm. Res
, vol.17
, pp. 1220-1227
-
-
Bouw, M.R.1
Gardmark, M.2
Hammarlund-Udenaes, M.3
-
41
-
-
0020515578
-
Brain microves-sel endothelial cells in tissue culture: A model for study of blood-brain barrier permeability
-
doi: 10.1002/ana.410140403
-
Bowman, P. D., Ennis, S. R., Rarey, K. E., Lorris Betz, A., and Goldstein, G. W. (1983). Brain microves-sel endothelial cells in tissue culture: a model for study of blood-brain barrier permeability. Ann. Neurol. 14, 396-402. doi: 10.1002/ana.410140403
-
(1983)
Ann. Neurol
, vol.14
, pp. 396-402
-
-
Bowman, P.D.1
Ennis, S.R.2
Rarey, K.E.3
Lorris Betz, A.4
Goldstein, G.W.5
-
42
-
-
0027637785
-
The blood-brain barrier
-
Bradbury, M. W. (1993). The blood-brain barrier. Exp. Physiol. 78, 453-472.
-
(1993)
Exp. Physiol
, vol.78
, pp. 453-472
-
-
Bradbury, M.W.1
-
43
-
-
0017689969
-
Morphology of blood-brain interfaces
-
doi: 10.1016/S0014-4835(77)80008-0
-
Brightman, M. W. (1977). Morphology of blood-brain interfaces. Exp. Eye Res. 25, 1-25. doi: 10.1016/S0014-4835(77)80008-0
-
(1977)
Exp. Eye Res
, vol.25
, pp. 1-25
-
-
Brightman, M.W.1
-
44
-
-
29244441701
-
ABCC drug efflux pumps and organic anion uptake transporters in human gliomas and the blood-tumor barrier
-
doi: 10.1158/0008-5472.CAN-05-1271
-
Bronger, H., Konig, J., Kopplow, K., Steiner, H. H., Ahmadi, R., Herold-Mende, C., et al. (2005). ABCC drug efflux pumps and organic anion uptake transporters in human gliomas and the blood-tumor barrier. Cancer Res. 65, 11419-11428. doi: 10.1158/0008-5472.CAN-05-1271
-
(2005)
Cancer Res
, vol.65
, pp. 11419-11428
-
-
Bronger, H.1
Konig, J.2
Kopplow, K.3
Steiner, H.H.4
Ahmadi, R.5
Herold-Mende, C.6
-
45
-
-
0026599146
-
Effect of histamine and antagonists on electrical-resistance across the blood-brain-barrier in rat brain-surface microvessels
-
doi: 10.1016/0006-8993(92)90374-I
-
Butt, A. M., and Jones, H. C. (1992). Effect of histamine and antagonists on electrical-resistance across the blood-brain-barrier in rat brain-surface microvessels. Brain Res. 569, 100-105. doi: 10.1016/0006-8993(92)90374-I
-
(1992)
Brain Res
, vol.569
, pp. 100-105
-
-
Butt, A.M.1
Jones, H.C.2
-
46
-
-
84864565346
-
ABC transporter function and regulation at the blood-spinal cord barrier
-
doi: 10.1038/jcbfm.2012.47
-
Campos, C. R., Schroter, C., Wang, X., and Miller, D. S. (2012). ABC transporter function and regulation at the blood-spinal cord barrier. J. Cereb. Blood Flow Metab. 32, 1559-1566. doi: 10.1038/jcbfm.2012.47
-
(2012)
J. Cereb. Blood Flow Metab
, vol.32
, pp. 1559-1566
-
-
Campos, C.R.1
Schroter, C.2
Wang, X.3
Miller, D.S.4
-
47
-
-
84866844026
-
Targeting blood-brain barrier sphingolipid signaling reduces basal P-glycoprotein activity and improves drug delivery to the brain
-
doi: 10.1073/pnas.1203534109
-
Cannon, R. E., Peart, J. C., Hawkins, B. T., Campos, C. R., and Miller, D. S. (2012). Targeting blood-brain barrier sphingolipid signaling reduces basal P-glycoprotein activity and improves drug delivery to the brain. Proc. Natl. Acad. Sci. U.S.A. 109, 15930-15935. doi: 10.1073/pnas.1203534109
-
(2012)
Proc. Natl. Acad. Sci. U.S.A
, vol.109
, pp. 15930-15935
-
-
Cannon, R.E.1
Peart, J.C.2
Hawkins, B.T.3
Campos, C.R.4
Miller, D.S.5
-
48
-
-
0016186511
-
Endothelial cell morphology in focal areas of in vivo Evans blue uptake in the young pig aorta. I. Quantitative light microscopic findings
-
doi: 10.1016/0014-4800(74)90082
-
Caplan, B. A., Gerrity, R. G., and Schwartz, C. J. (1974). Endothelial cell morphology in focal areas of in vivo Evans blue uptake in the young pig aorta. I. Quantitative light microscopic findings. Exp. Mol. Pathol. 21, 102-117. doi: 10.1016/0014-4800(74)90082-3
-
(1974)
Exp. Mol. Pathol
, vol.21
, pp. 102-117
-
-
Caplan, B.A.1
Gerrity, R.G.2
Schwartz, C.J.3
-
49
-
-
34547645047
-
Modelling of the blood-brain barrier in drug discovery and development
-
doi: 10.1038/ nrd2368
-
Cecchelli, R., Berezowski, V., Lundquist, S., Culot, M., Renftel, M., Dehouck, M. P., et al. (2007). Modelling of the blood-brain barrier in drug discovery and development. Nat. Rev. Drug Discov. 6, 650-661. doi: 10.1038/ nrd2368
-
(2007)
Nat. Rev. Drug Discov
, vol.6
, pp. 650-661
-
-
Cecchelli, R.1
Berezowski, V.2
Lundquist, S.3
Culot, M.4
Renftel, M.5
Dehouck, M.P.6
-
50
-
-
0033526177
-
In vitro model for evaluating drug transport across the blood-brain barrier
-
doi: 10.1016/S0169-409X(98)00083-0
-
Cecchelli, R., Dehouck, B., Descamps, L., Fenart, L., Buée-Scherrer, V., Duhem, C., et al. (1999). In vitro model for evaluating drug transport across the blood-brain barrier. Adv. Drug Deliv. Rev. 36, 165-178. doi: 10.1016/S0169-409X(98)00083-0
-
(1999)
Adv. Drug Deliv. Rev
, vol.36
, pp. 165-178
-
-
Cecchelli, R.1
Dehouck, B.2
Descamps, L.3
Fenart, L.4
Buée-Scherrer, V.5
Duhem, C.6
-
51
-
-
33745339891
-
Characteristics of substance p transport across the blood-brain barrier
-
doi: 10.1007/s11095-006-0068-1
-
Chappa, A., Audus, K., and Lunte, S. (2006). Characteristics of substance p transport across the blood-brain barrier. Pharm. Res. 23, 1201-1208. doi: 10.1007/s11095-006-0068-1
-
(2006)
Pharm. Res
, vol.23
, pp. 1201-1208
-
-
Chappa, A.1
Audus, K.2
Lunte, S.3
-
52
-
-
33847767113
-
Mechanotransduction and endothelial cell home-ostasis: The wisdom of the cell
-
doi: 10.1152/ajpheart.01047.2006
-
Chien, S. (2007). Mechanotransduction and endothelial cell home-ostasis: the wisdom of the cell. Am. J. Physiol. Heart Circ. Physiol. 292, H1209-H1224. doi: 10.1152/ajpheart.01047.2006
-
(2007)
Am. J. Physiol. Heart Circ. Physiol
, vol.292
-
-
Chien, S.1
-
53
-
-
0034888307
-
Affinity for the P-glycoprotein efflux pump at the blood-brain barrier may explain the lack of CNS side-effects of modern antihistamines
-
doi: 10.3109/10611860108997930
-
Chishty, M., Reichel, A., Siva, J., Abbott, N. J., and Begley, D. J. (2001). Affinity for the P-glycoprotein efflux pump at the blood-brain barrier may explain the lack of CNS side-effects of modern antihistamines. J. Drug Target. 9, 223-228. doi: 10.3109/10611860108997930
-
(2001)
J. Drug Target
, vol.9
, pp. 223-228
-
-
Chishty, M.1
Reichel, A.2
Siva, J.3
Abbott, N.J.4
Begley, D.J.5
-
54
-
-
84856055345
-
Lessons from the endothe-lial junctional mechanosensory complex
-
Conway, D., and Schwartz, M. A. (2012). Lessons from the endothe-lial junctional mechanosensory complex. F1000 Biol. Rep. 4, 1.
-
(2012)
F1000 Biol. Rep
, vol.4
, pp. 1
-
-
Conway, D.1
Schwartz, M.A.2
-
55
-
-
78651133453
-
The permeability of capillaries in various organs as determined by use of the indicator diffusion method
-
doi: 10.1111/j.1748-1716.1963.tb02652.x
-
Crone, C. (1963). The permeability of capillaries in various organs as determined by use of the indicator diffusion method. Acta Physiol. Scand. 58, 292-305. doi: 10.1111/j.1748-1716.1963.tb02652.x
-
(1963)
Acta Physiol. Scand
, vol.58
, pp. 292-305
-
-
Crone, C.1
-
56
-
-
0020081135
-
Electrical resistance of brain microvascular endothelium
-
doi: 10.1016/0006-8993(82)91227-6
-
Crone, C., and Olesen, S. P. (1982). Electrical resistance of brain microvascular endothelium. Brain Res. 241, 49-55. doi: 10.1016/0006-8993(82)91227-6
-
(1982)
Brain Res
, vol.241
, pp. 49-55
-
-
Crone, C.1
Olesen, S.P.2
-
57
-
-
79955752356
-
The role of shear stress in blood-brain barrier endothelial physiology
-
doi: 10.1186/1471-2202-12-40
-
Cucullo, L., Hossain, M., Puvenna, V., Marchi, N., and Janigro, D. (2011). The role of shear stress in blood-brain barrier endothelial physiology. BMC Neurosci. 12:40. doi: 10.1186/1471-2202-12-40
-
(2011)
BMC Neurosci
, vol.12
, pp. 40
-
-
Cucullo, L.1
Hossain, M.2
Puvenna, V.3
Marchi, N.4
Janigro, D.5
-
58
-
-
79957934229
-
Brain microvas-cular pericytes in health and disease
-
doi: 10.1007/s00401-011-0847-6
-
Dalkara, T., Gursoy-Ozdemir, Y., and Yemisci, M. (2011). Brain microvas-cular pericytes in health and disease. Acta Neuropathol. 122, 1-9. doi: 10.1007/s00401-011-0847-6
-
(2011)
Acta Neuropathol
, vol.122
, pp. 1-9
-
-
Dalkara, T.1
Gursoy-Ozdemir, Y.2
Yemisci, M.3
-
59
-
-
0032762318
-
Blood-brain barrier tight junction disruption in human immunodeficiency virus-1 encephalitis
-
doi: 10.1016/S0002-9440(10)65511-3
-
Dallasta, L. M., Pisarov, L. A., Esplen, J. E., Werley, J. V., Moses, A. V., Nelson, J. A., et al. (1999). Blood-brain barrier tight junction disruption in human immunodeficiency virus-1 encephalitis. Am. J. Pathol. 155, 1915-1927. doi: 10.1016/S0002-9440(10)65511-3
-
(1999)
Am. J. Pathol
, vol.155
, pp. 1915-1927
-
-
Dallasta, L.M.1
Pisarov, L.A.2
Esplen, J.E.3
Werley, J.V.4
Moses, A.V.5
Nelson, J.A.6
-
60
-
-
84870408539
-
The blood-brain barrier in health and disease
-
doi:10.1002/ana.23648
-
Daneman, R. (2012). The blood-brain barrier in health and disease. Ann. Neurol. 72, 648-672. doi:10.1002/ana.23648.
-
(2012)
Ann. Neurol
, vol.72
, pp. 648-672
-
-
Daneman, R.1
-
61
-
-
58849119932
-
Wnt/beta-catenin sig naling is required for CNS, but not non-CNS, angiogenesis
-
doi: 10.1073/pnas.0805165106
-
Daneman, R., Agalliu, D., Zhou, L., Kuhnert, F., Kuo, C. J., and Barres, A. (2009). Wnt/beta-catenin sig naling is required for CNS, but not non-CNS, angiogenesis. Proc. Natl. Acad. Sci. U.S.A. 106, 641-646. doi: 10.1073/pnas.0805165106
-
(2009)
Proc. Natl. Acad. Sci. U.S.A
, vol.106
, pp. 641-646
-
-
Daneman, R.1
Agalliu, D.2
Zhou, L.3
Kuhnert, F.4
Kuo, C.J.5
Barres, A.6
-
62
-
-
78649487239
-
Pericytes are required for blood-brain barrier integrity during embryogen-esis
-
doi:, 10.1038/nature09513
-
Daneman, R., Zhou, L., Kebede, A. A., and Barres, B. A. (2010). Pericytes are required for blood-brain barrier integrity during embryogen-esis. Nature 468, 562-566. doi: 10.1038/nature09513
-
(2010)
Nature
, vol.468
, pp. 562-566
-
-
Daneman, R.1
Zhou, L.2
Kebede, A.A.3
Barres, B.A.4
-
63
-
-
0036316548
-
Blood-brain barrier breakdown in septic encephalopathy and brain tumours
-
Davies, D. C. (2002). Blood-brain barrier breakdown in septic encephalopathy and brain tumours. J. Anat. 200, 639-646. doi: 10.1046/j.1469-7580.2002.00065.x
-
(2002)
J. Anat
, vol.200
, pp. 639-646
-
-
Davies, D.C.1
-
64
-
-
0003340046
-
Principles of membrane transport
-
Section 6:, The Gastrointestinal System, ed B. Rauner (Bethesda, MD: American Physiological Society
-
Dawson, D. (1991). "Principles of membrane transport," in Handbook of Physiology, Section 6: The Gastrointestinal System, ed B. Rauner (Bethesda, MD: American Physiological Society), 1-45.
-
(1991)
Handbook of Physiology
, pp. 1-45
-
-
Dawson, D.1
-
65
-
-
33847037399
-
Drug targeting to the brain
-
doi: 10.1146/annurev. pharmtox.47.120505.105237
-
de Boer, A. G., and Gaillard, P. J. (2007). Drug targeting to the brain. Annu. Rev. Pharmacol. Toxicol. 47, 323-355. doi: 10.1146/annurev. pharmtox.47.120505.105237
-
(2007)
Annu. Rev. Pharmacol. Toxicol
, vol.47
, pp. 323-355
-
-
de Boer, A.G.1
Gaillard, P.J.2
-
66
-
-
0013117931
-
The role of drug transporters at the blood-brain barrier
-
doi: 10.1146/annurev.pharmtox.43. 100901.140204
-
de Boer, A. G., Van Der Sandt, I. J., and Gaillard, P. J. (2003). The role of drug transporters at the blood-brain barrier. Annu. Rev. Pharmacol. Toxicol. 43, 629-656. doi: 10.1146/annurev.pharmtox.43. 100901.140204
-
(2003)
Annu. Rev. Pharmacol. Toxicol
, vol.43
, pp. 629-656
-
-
de Boer, A.G.1
van der Sandt, I.J.2
Gaillard, P.J.3
-
67
-
-
0018849619
-
Gamma-glutamyl- transferase transpeptidase in isolated brain endothelial-cells - induction by glial-cells invitro
-
doi: 10.1126/science.6101511
-
debault, L. E., and Cancilla, P. A. (1980). Gamma-glutamyl- transferase transpeptidase in isolated brain endothelial-cells - induction by glial-cells invitro. Science 207, 653-655. doi: 10.1126/science.6101511
-
(1980)
Science
, vol.207
, pp. 653-655
-
-
Debault, L.E.1
Cancilla, P.A.2
-
68
-
-
1842632667
-
Endothelial cell-cell junctions: Happy together
-
doi: 10.1038/nrm1357
-
Dejana, E. (2004). Endothelial cell-cell junctions: happy together. Nat. Rev. Mol. Cell Biol. 5, 261-270. doi: 10.1038/nrm1357
-
(2004)
Nat. Rev. Mol. Cell Biol
, vol.5
, pp. 261-270
-
-
Dejana, E.1
-
69
-
-
74849117723
-
The neurovas-cular unit in the setting of stroke
-
doi: 10.1111/j.1365-2796.2009.02199.x
-
Del Zoppo, G. J. (2010). The neurovas-cular unit in the setting of stroke. J. Intern. Med. 267, 156-171. doi: 10.1111/j.1365-2796.2009.02199.x
-
(2010)
J. Intern. Med
, vol.267
, pp. 156-171
-
-
Del Zoppo, G.J.1
-
70
-
-
17444406065
-
Permeability studies on in vitro blood-brain barrier models: Physiology, pathology, and pharmacology
-
doi: 10.1007/s10571-004-1377-8
-
Deli, M. A., Abraham, C. S., Kataoka, Y., and Niwa, M. (2005). Permeability studies on in vitro blood-brain barrier models: physiology, pathology, and pharmacology. Cell. Mol. Neurobiol. 25, 59-127. doi: 10.1007/s10571-004-1377-8
-
(2005)
Cell. Mol. Neurobiol
, vol.25
, pp. 59-127
-
-
Deli, M.A.1
Abraham, C.S.2
Kataoka, Y.3
Niwa, M.4
-
71
-
-
0036627484
-
Drug transport to the brain: Key roles for the efflux pump P-glycoprotein in the blood-brain barrier
-
doi: 10.1016/S1537-1891(02)00201-X
-
Demeule, M., Regina, A., Jodoin, J., Laplante, A., Dagenais, C., Berthelet, F., et al. (2002). Drug transport to the brain: key roles for the efflux pump P-glycoprotein in the blood-brain barrier. Vascul.Pharmacol. 38, 339-348. doi: 10.1016/S1537-1891(02)00201-X
-
(2002)
Vascul.Pharmacol
, vol.38
, pp. 339-348
-
-
Demeule, M.1
Regina, A.2
Jodoin, J.3
Laplante, A.4
Dagenais, C.5
Berthelet, F.6
-
72
-
-
34250623663
-
Blood-brain barrier pathology in Alzheimer's and Parkinson's disease: Implications for drug therapy
-
Desai, B. S., Monahan, A. J., Carvey, P. M., and Hendey, B. (2007). Blood-brain barrier pathology in Alzheimer's and Parkinson's disease: implications for drug therapy. Cell Transplant. 16, 285-299.
-
(2007)
Cell Transplant
, vol.16
, pp. 285-299
-
-
Desai, B.S.1
Monahan, A.J.2
Carvey, P.M.3
Hendey, B.4
-
73
-
-
0029658974
-
Detection of P-glycoprotein expression by tumoral cells with NBDL-CsA, a fluorescent derivative of cyclosporin A
-
doi: 10.1097/00001813-199605000-00004
-
Didier, A., Tiberghien, F., Wenger, R., and Loor, F. (1996). Detection of P-glycoprotein expression by tumoral cells with NBDL-CsA, a fluorescent derivative of cyclosporin A. Anticancer Drugs 7, 257-265. doi: 10.1097/00001813-199605000-00004
-
(1996)
Anticancer Drugs
, vol.7
, pp. 257-265
-
-
Didier, A.1
Tiberghien, F.2
Wenger, R.3
Loor, F.4
-
74
-
-
84879422098
-
High wall shear stress and spatial gradients in vascular pathology: A review
-
doi: 10.1007/s10439-012-0695-0
-
Dolan, J. M., Kolega, J., and Meng, H. (2013). High wall shear stress and spatial gradients in vascular pathology: a review. Ann. Biomed. Eng. 41, 1411-1427. doi: 10.1007/s10439-012-0695-0
-
(2013)
Ann. Biomed. Eng
, vol.41
, pp. 1411-1427
-
-
Dolan, J.M.1
Kolega, J.2
Meng, H.3
-
75
-
-
0021041669
-
The vascularization of the human cerebellar cortex
-
doi: 10.1016/0361-9230(83)90116-8
-
Duvernoy, H., Delon, S., and Vannson, J. L. (1983). The vascularization of the human cerebellar cortex. Brain Res. Bull. 11, 419-480. doi: 10.1016/0361-9230(83)90116-8
-
(1983)
Brain Res. Bull
, vol.11
, pp. 419-480
-
-
Duvernoy, H.1
Delon, S.2
Vannson, J.L.3
-
76
-
-
36148984590
-
The circumventricular organs: An atlas of comparative anatomy and vascularization
-
doi: 10.1016/j.brainresrev.2007.06.002
-
Duvernoy, H. M., and Risold, P. Y. (2007). The circumventricular organs: an atlas of comparative anatomy and vascularization. Brain Res. Rev. 56, 119-147. doi: 10.1016/j.brainresrev.2007.06.002
-
(2007)
Brain Res. Rev
, vol.56
, pp. 119-147
-
-
Duvernoy, H.M.1
Risold, P.Y.2
-
77
-
-
48749093647
-
Environmental enrichment, exercise and corticosterone affect endothe-lial cell proliferation in adult rat hippocampus and prefrontal cortex
-
doi: 10.1016/j.neulet.2008.06.085
-
Ekstrand, J., Hellsten, J., and Tingstrom, A. (2008). Environmental enrichment, exercise and corticosterone affect endothe-lial cell proliferation in adult rat hippocampus and prefrontal cortex. Neurosci. Lett. 442, 203-207. doi: 10.1016/j.neulet.2008.06.085
-
(2008)
Neurosci. Lett
, vol.442
, pp. 203-207
-
-
Ekstrand, J.1
Hellsten, J.2
Tingstrom, A.3
-
78
-
-
33745521753
-
The rat blood-brain barrier transcriptome
-
doi: 10.1038/sj.jcbfm.9600249
-
Enerson, B. E., and Drewes, L. R. (2006). The rat blood-brain barrier transcriptome. J. Cereb. Blood Flow Metab. 26, 959-973. doi: 10.1038/sj.jcbfm.9600249
-
(2006)
J. Cereb. Blood Flow Metab
, vol.26
, pp. 959-973
-
-
Enerson, B.E.1
Drewes, L.R.2
-
79
-
-
48949117580
-
The blood-central nervous system barriers actively control immune cell entry into the central nervous system
-
doi: 10.2174/138161208784705432
-
Engelhardt, B. (2008a). The blood-central nervous system barriers actively control immune cell entry into the central nervous system. Curr. Pharm. Des. 14, 1555-1565. doi: 10.2174/138161208784705432
-
(2008)
Curr. Pharm. Des
, vol.14
, pp. 1555-1565
-
-
Engelhardt, B.1
-
80
-
-
53049110581
-
Immune cell entry into the central nervous system: Involvement of adhesion molecules and chemokines
-
doi: 10.1016/j.jns.2008.05.019
-
Engelhardt, B. (2008b). Immune cell entry into the central nervous system: involvement of adhesion molecules and chemokines. J. Neurol. Sci. 274, 23-26. doi: 10.1016/j.jns.2008.05.019
-
(2008)
J. Neurol. Sci
, vol.274
, pp. 23-26
-
-
Engelhardt, B.1
-
81
-
-
0001331302
-
The viscosity of the blood in narrow capillary tubes
-
Fahraeus, R., and Lindqvist, T. (1931). The viscosity of the blood in narrow capillary tubes. Am. J. Physiol. 96, 562-568.
-
(1931)
Am. J. Physiol
, vol.96
, pp. 562-568
-
-
Fahraeus, R.1
Lindqvist, T.2
-
82
-
-
0035047718
-
Cerebral microvascular pathology in aging and Alzheimer's disease
-
doi: 10.1016/S0301-0082(00)00068-X
-
Farkas, E., and Luiten, P. G. M. (2001). Cerebral microvascular pathology in aging and Alzheimer's disease. Prog. Neurobiol. 64, 575-611. doi: 10.1016/S0301-0082(00)00068-X
-
(2001)
Prog. Neurobiol
, vol.64
, pp. 575-611
-
-
Farkas, E.1
Luiten, P.G.M.2
-
83
-
-
0023731806
-
Structural and functional variations in capillary systems within the brain
-
doi: 10.1111/j.1749-6632.1988.tb51416.x
-
Fenstermacher, J., Gross, P., Sposito, N., Acuff, V., Pettersen, S., and Gruber, K. (1988). Structural and functional variations in capillary systems within the brain. Ann. N.Y. Acad. Sci. 529, 21-30. doi: 10.1111/j.1749-6632.1988.tb51416.x
-
(1988)
Ann. N.Y. Acad. Sci
, vol.529
, pp. 21-30
-
-
Fenstermacher, J.1
Gross, P.2
Sposito, N.3
Acuff, V.4
Pettersen, S.5
Gruber, K.6
-
84
-
-
78650645093
-
Pericytes in capillaries are contractile in vivo, but arteri-oles mediate functional hyperemia in the mouse brain
-
doi: 10.1073/pnas.1011321108
-
Fernandez-Klett, F., Offenhauser, N., Dirnagl, U., Priller, J., and Lindauer, U. (2010). Pericytes in capillaries are contractile in vivo, but arteri-oles mediate functional hyperemia in the mouse brain. Proc. Natl. Acad. Sci. U.S.A. 107, 22290-22295. doi: 10.1073/pnas.1011321108
-
(2010)
Proc. Natl. Acad. Sci. U.S.A
, vol.107
, pp. 22290-22295
-
-
Fernandez-Klett, F.1
Offenhauser, N.2
Dirnagl, U.3
Priller, J.4
Lindauer, U.5
-
85
-
-
65249154249
-
Sorting out astrocyte physiology from pharmacology
-
doi: 10.1146/ annurev.pharmtox.011008.145602
-
Fiacco, T. A., Agulhon, C., and McCarthy, K. D. (2009). Sorting out astrocyte physiology from pharmacology. Annu. Rev. Pharmacol. Toxicol. 49, 151-174. doi: 10.1146/ annurev.pharmtox.011008.145602
-
(2009)
Annu. Rev. Pharmacol. Toxicol
, vol.49
, pp. 151-174
-
-
Fiacco, T.A.1
Agulhon, C.2
McCarthy, K.D.3
-
86
-
-
0037308502
-
Dietary constraints on encephalization in primates
-
doi: 10.1002/ajpa.10136
-
Fish, J. L., and Lockwood, C. A. (2003). Dietary constraints on encephalization in primates. Am. J. Phys. Anthropol. 120, 171-181. doi: 10.1002/ajpa.10136
-
(2003)
Am. J. Phys. Anthropol
, vol.120
, pp. 171-181
-
-
Fish, J.L.1
Lockwood, C.A.2
-
87
-
-
62949153790
-
Pericyte signaling in the neurovascular unit
-
doi: 10.1161/STROKEAHA.108.533117
-
Fisher, M. (2009). Pericyte signaling in the neurovascular unit. Stroke 40, S13-S15. doi: 10.1161/STROKEAHA.108.533117
-
(2009)
Stroke
, vol.40
-
-
Fisher, M.1
-
88
-
-
0033528231
-
An improved low-permeability in vitro-model of the blood-brain barrier: Transport studies on retinoids, sucrose, haloperi-dol, caffeine and mannitol
-
. doi: 10.1016/S0006-8993(98)01282-7
-
Franke, H., Galla, H.-J., and Beuckmann, C. T. (1999). An improved low-permeability in vitro-model of the blood-brain barrier: transport studies on retinoids, sucrose, haloperi-dol, caffeine and mannitol. Brain Res. 818, 65-71. doi: 10.1016/S0006-8993(98)01282-7
-
(1999)
Brain Res
, vol.818
, pp. 65-71
-
-
Franke, H.1
Galla, H.-J.2
Beuckmann, C.T.3
-
89
-
-
0034775961
-
Investigation of the metabolism of substance P at the blood-brain barrier using capillary electrophoresis with laser-induced fluorescence detection
-
Freed, A. L., Audus, K. L., and Lunte, S. M. (2001). Investigation of the metabolism of substance P at the blood-brain barrier using capillary electrophoresis with laser-induced fluorescence detection. Electrophoresis 22, 3778-3784.
-
(2001)
Electrophoresis
, vol.22
, pp. 3778-3784
-
-
Freed, A.L.1
Audus, K.L.2
Lunte, S.M.3
-
90
-
-
78149314205
-
Specification and morphogenesis of astro-cytes
-
doi: 10.1126/science.1190928
-
Freeman, M. R. (2010). Specification and morphogenesis of astro-cytes. Science 330, 774-778. doi: 10.1126/science.1190928
-
(2010)
Science
, vol.330
, pp. 774-778
-
-
Freeman, M.R.1
-
91
-
-
0029850424
-
Pyridostigmine brain penetration under stress enhances neuronal excitability and induces early immediate transcriptional response
-
doi: 10.1038/nm1296-1382
-
Friedman, A., Kaufer, D., Shemer, J., Hendler, I., Soreq, H., and Tur-Kaspa, I. (1996). Pyridostigmine brain penetration under stress enhances neuronal excitability and induces early immediate transcriptional response. Nat. Med. 2, 1382-1385. doi: 10.1038/nm1296-1382
-
(1996)
Nat. Med
, vol.2
, pp. 1382-1385
-
-
Friedman, A.1
Kaufer, D.2
Shemer, J.3
Hendler, I.4
Soreq, H.5
Tur-Kaspa, I.6
-
92
-
-
34247369372
-
QSAR study on permeability of hydrophobic compounds with artificial membranes
-
doi: 10.1016/j.bmc.2007.03.040
-
Fujikawa, M., Nakao, K., Shimizu, R., and Akamatsu, M. (2007). QSAR study on permeability of hydrophobic compounds with artificial membranes. Bioorg. Med. Chem. 15, 3756-3767. doi: 10.1016/j.bmc.2007.03.040
-
(2007)
Bioorg. Med. Chem
, vol.15
, pp. 3756-3767
-
-
Fujikawa, M.1
Nakao, K.2
Shimizu, R.3
Akamatsu, M.4
-
93
-
-
33645747414
-
Claudins in occluding junctions of humans and flies
-
doi: 10.1016/j.tcb.2006.02.006
-
Furuse, M., and Tsukita, S. (2006). Claudins in occluding junctions of humans and flies. Trends Cell Biol. 16, 181-188. doi: 10.1016/j.tcb.2006.02.006
-
(2006)
Trends Cell Biol
, vol.16
, pp. 181-188
-
-
Furuse, M.1
Tsukita, S.2
-
94
-
-
0034104737
-
Circumventricular organs: Definition and role in the regulation of endocrine and autonomic function
-
doi: 10.1046/j.1440-1681.2000.03259.x
-
Ganong, W. F. (2000). Circumventricular organs: definition and role in the regulation of endocrine and autonomic function. Clin. Exp. Pharmacol. Physiol. 27, 422-427. doi: 10.1046/j.1440-1681.2000.03259.x
-
(2000)
Clin. Exp. Pharmacol. Physiol
, vol.27
, pp. 422-427
-
-
Ganong, W.F.1
-
95
-
-
77649216536
-
Membrane transporters in drug development
-
doi: 10.1038/nrd3028
-
Giacomini, K. M., Huang, S. M., Tweedie, D. J., Benet, L. Z., Brouwer, K. L., Chu, X., et al. (2010). Membrane transporters in drug development. Nat. Rev. Drug Discov. 9, 215-236. doi: 10.1038/nrd3028
-
(2010)
Nat. Rev. Drug Discov
, vol.9
, pp. 215-236
-
-
Giacomini, K.M.1
Huang, S.M.2
Tweedie, D.J.3
Benet, L.Z.4
Brouwer, K.L.5
Chu, X.6
-
96
-
-
33746729791
-
Understanding patho-genesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research
-
doi: 10.1093/brain/awl075
-
Gold, R., Linington, C., and Lassmann, H. (2006). Understanding patho-genesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research. Brain 129, 1953-1971. doi: 10.1093/brain/awl075
-
(2006)
Brain
, vol.129
, pp. 1953-1971
-
-
Gold, R.1
Linington, C.2
Lassmann, H.3
-
97
-
-
0031464488
-
Molecular factors influencing drug transfer across the blood-brain barrier
-
doi: 10.1111/j.2042-7158.1997.tb06072.x
-
Gratton, J. A., Abraham, M. H., Bradbury, M. W., and Chadha, H. S. (1997). Molecular factors influencing drug transfer across the blood-brain barrier. J. Pharm. Pharmacol. 49, 1211-1216. doi: 10.1111/j.2042-7158.1997.tb06072.x
-
(1997)
J. Pharm. Pharmacol
, vol.49
, pp. 1211-1216
-
-
Gratton, J.A.1
Abraham, M.H.2
Bradbury, M.W.3
Chadha, H.S.4
-
98
-
-
0022978771
-
Differences in function and structure of the capillary endothe-lium in gray matter, white matter and a circumventricular organ of rat brain
-
Gross, P. M., Sposito, N. M., Pettersen, S. E., and Fenstermacher, J. D. (1986). Differences in function and structure of the capillary endothe-lium in gray matter, white matter and a circumventricular organ of rat brain. Blood Vessels 23, 261-270.
-
(1986)
Blood Vessels
, vol.23
, pp. 261-270
-
-
Gross, P.M.1
Sposito, N.M.2
Pettersen, S.E.3
Fenstermacher, J.D.4
-
99
-
-
0035156232
-
Progress and limitations in the use of in vitro cell cultures to serve as a permeability screen for the blood-brain barrier
-
doi: 10.1002/jps.1119
-
Gumbleton, M., and Audus, K. L. (2001). Progress and limitations in the use of in vitro cell cultures to serve as a permeability screen for the blood-brain barrier. J. Pharm. Sci. 90, 1681-1698. doi: 10.1002/jps.1119
-
(2001)
J. Pharm. Sci
, vol.90
, pp. 1681-1698
-
-
Gumbleton, M.1
Audus, K.L.2
-
100
-
-
58049213928
-
Mechanotransduction in vascular physiology and atherogenesis
-
doi: 10.1038/nrm2596
-
Hahn, C., and Schwartz, M. A. (2009). Mechanotransduction in vascular physiology and atherogenesis. Nat. Rev. Mol. Cell Biol. 10, 53-62. doi: 10.1038/nrm2596
-
(2009)
Nat. Rev. Mol. Cell Biol
, vol.10
, pp. 53-62
-
-
Hahn, C.1
Schwartz, M.A.2
-
101
-
-
77951929051
-
Integrated brain circuits: Astrocytic networks modulate neu-ronal activity and behavior
-
doi: 10.1146/annurev-physiol-021909-135843
-
Halassa, M. M., and Haydon, P. G. (2010). Integrated brain circuits: astrocytic networks modulate neu-ronal activity and behavior. Annu. Rev. Physiol. 72, 335-355. doi: 10.1146/annurev-physiol-021909-135843
-
(2010)
Annu. Rev. Physiol
, vol.72
, pp. 335-355
-
-
Halassa, M.M.1
Haydon, P.G.2
-
102
-
-
78049253786
-
Pericyte-mediated regulation of capillary diameter: A component of neurovascular coupling in health and disease
-
doi: 10.3389/fnene.2010.00005
-
Hamilton, N. B., Attwell, D., and Hall, C. N. (2010). Pericyte-mediated regulation of capillary diameter: a component of neurovascular coupling in health and disease. Front. Neuroenergetics 2:5. doi: 10.3389/fnene.2010.00005
-
(2010)
Front. Neuroenergetics
, vol.2
, pp. 5
-
-
Hamilton, N.B.1
Attwell, D.2
Hall, C.N.3
-
103
-
-
63349088174
-
Methodologies to assess brain drug delivery in lead optimization
-
doi: 10.2174/156802609787521607
-
Hammarlund-Udenaes, M., Bredberg, U., and Friden, M. (2009). Methodologies to assess brain drug delivery in lead optimization. Curr. Top. Med. Chem. 9, 148-162. doi: 10.2174/156802609787521607
-
(2009)
Curr. Top. Med. Chem
, vol.9
, pp. 148-162
-
-
Hammarlund-Udenaes, M.1
Bredberg, U.2
Friden, M.3
-
104
-
-
45949107902
-
On the rate and extent of drug delivery to the brain
-
doi: 10.1007/s11095-007-9502-2
-
Hammarlund-Udenaes, M., Friden, M., Syvanen, S., and Gupta, A. (2008). On the rate and extent of drug delivery to the brain. Pharm. Res. 25, 1737-1750. doi: 10.1007/s11095-007-9502-2
-
(2008)
Pharm. Res
, vol.25
, pp. 1737-1750
-
-
Hammarlund-Udenaes, M.1
Friden, M.2
Syvanen, S.3
Gupta, A.4
-
105
-
-
33947723274
-
The impact of glia-derived extracellular matrices on the barrier function of cerebral endothelial cells: An in vitro study
-
doi: 10.1016/j.yexcr. 2007.01.024
-
Hartmann, C., Zozulya, A., Wegener, J., and Galla, H. J. (2007). The impact of glia-derived extracellular matrices on the barrier function of cerebral endothelial cells: an in vitro study. Exp. Cell Res. 313, 1318-1325. doi: 10.1016/j.yexcr. 2007.01.024
-
(2007)
Exp. Cell Res
, vol.313
, pp. 1318-1325
-
-
Hartmann, C.1
Zozulya, A.2
Wegener, J.3
Galla, H.J.4
-
106
-
-
79951933153
-
ABC transporters in the CNS - an inventory
-
doi: 10.2174/138920111795164020
-
Hartz, A. M., and Bauer, B. (2011). ABC transporters in the CNS - an inventory. Curr. Pharm. Biotechnol. 12, 656-673. doi: 10.2174/138920111795164020
-
(2011)
Curr. Pharm. Biotechnol
, vol.12
, pp. 656-673
-
-
Hartz, A.M.1
Bauer, B.2
-
107
-
-
77951078680
-
Restoring blood-brain barrier P-glycoprotein reduces brain amyloid-beta in a mouse model of Alzheimer's disease
-
doi: 10.1124/mol.109.061754
-
Hartz, A. M., Miller, D. S., and Bauer, B. (2010). Restoring blood-brain barrier P-glycoprotein reduces brain amyloid-beta in a mouse model of Alzheimer's disease. Mol. Pharmacol. 77, 715-723. doi: 10.1124/mol.109.061754
-
(2010)
Mol. Pharmacol
, vol.77
, pp. 715-723
-
-
Hartz, A.M.1
Miller, D.S.2
Bauer, B.3
-
108
-
-
4944230261
-
Rapid regulation of p-glycoprotein at the blood-brain barrier by endothelin-1
-
doi: 10.1124/mol.104.001503
-
Hartz, A. M. S., Bauer, B., Fricker, G., and Miller, D. S. (2004). Rapid regulation of p-glycoprotein at the blood-brain barrier by endothelin-1. Mol. Pharmacol. 66, 387-394. doi: 10.1124/mol.104.001503
-
(2004)
Mol. Pharmacol
, vol.66
, pp. 387-394
-
-
Hartz, A.M.S.1
Bauer, B.2
Fricker, G.3
Miller, D.S.4
-
109
-
-
17644363679
-
In search of the astrocytic factor(s) modulating blood-brain barrier functions in brain capillary endothelial cells in vitro
-
doi: 10.1007/s10571-004-1375-x
-
Haseloff, R. F., Blasig, I. E., Bauer, H. C., and Bauer, H. (2005). In search of the astrocytic factor(s) modulating blood-brain barrier functions in brain capillary endothelial cells in vitro. Cell. Mol. Neurobiol. 25, 25-39. doi: 10.1007/s10571-004-1375-x
-
(2005)
Cell. Mol. Neurobiol
, vol.25
, pp. 25-39
-
-
Haseloff, R.F.1
Blasig, I.E.2
Bauer, H.C.3
Bauer, H.4
-
110
-
-
79960279229
-
Development of a three-dimensional, all- human in vitro model of the blood-brain barrier using mono-, co-, and tri-cultivation Transwell models
-
doi: 10.1016/j.jneumeth.2011.05.012
-
Hatherell, K., Couraud, P. O., Romero, I. A., Weksler, B., and Pilkington, G. J. (2011). Development of a three-dimensional, all- human in vitro model of the blood-brain barrier using mono-, co-, and tri-cultivation Transwell models. J. Neurosci. Methods 199, 223-229. doi: 10.1016/j.jneumeth.2011.05.012
-
(2011)
J. Neurosci. Methods
, vol.199
, pp. 223-229
-
-
Hatherell, K.1
Couraud, P.O.2
Romero, I.A.3
Weksler, B.4
Pilkington, G.J.5
-
111
-
-
1842578299
-
Capillary flow and diameter changes during reperfusion after global cerebral ischemia studied by intravital video microscopy
-
doi: 10.1097/00004647-200404000-00003
-
Hauck, E. F., Apostel, S., Hoffmann, J. F., Heimann, A., and Kempski, O. (2004). Capillary flow and diameter changes during reperfusion after global cerebral ischemia studied by intravital video microscopy. J. Cereb. Blood Flow Metab. 24, 383-391. doi: 10.1097/00004647-200404000-00003
-
(2004)
J. Cereb. Blood Flow Metab
, vol.24
, pp. 383-391
-
-
Hauck, E.F.1
Apostel, S.2
Hoffmann, J.F.3
Heimann, A.4
Kempski, O.5
-
112
-
-
22944483792
-
The blood-brain bar-rier/neurovascular unit in health and disease
-
doi: 10.1124/pr.57.2.4
-
Hawkins, B. T., and Davis, T. P. (2005). The blood-brain bar-rier/neurovascular unit in health and disease. Pharmacol. Rev. 57, 173-185. doi: 10.1124/pr.57.2.4
-
(2005)
Pharmacol. Rev
, vol.57
, pp. 173-185
-
-
Hawkins, B.T.1
Davis, T.P.2
-
113
-
-
75349108100
-
Rapid, reversible modulation of blood-brain barrier p-glycoprotein transport activity by vascular endothelial growth factor
-
doi: 10.1523/JNEUROSCI.5103-09.2010
-
Hawkins, B. T., Sykes, D. B., and Miller, D. S. (2010). Rapid, reversible modulation of blood-brain barrier p-glycoprotein transport activity by vascular endothelial growth factor. J. Neurosci. 30, 1417-1425. doi: 10.1523/JNEUROSCI.5103-09.2010
-
(2010)
J. Neurosci
, vol.30
, pp. 1417-1425
-
-
Hawkins, B.T.1
Sykes, D.B.2
Miller, D.S.3
-
114
-
-
0036760638
-
The complementary membranes forming the blood-brain barrier
-
doi: 10.1080/15216540214541
-
Hawkins, R. A., Peterson, D. R., and Vina, J. R. (2002). The complementary membranes forming the blood-brain barrier. IUBMB Life 54, 101-107. doi: 10.1080/15216540214541
-
(2002)
IUBMB Life
, vol.54
, pp. 101-107
-
-
Hawkins, R.A.1
Peterson, D.R.2
Vina, J.R.3
-
115
-
-
38749114645
-
Novel three-dimensional analysis tool for vascular trees indicates complete micro-networks, not single capillaries, as the angiogenic endpoint in mice overexpressing human VEGF(165) in the brain
-
doi: 10.1016/j.neuroimage.2007.10.054
-
Heinzer, S., Kuhn, G., Krucker, T., Meyer, E., Ulmann-Schuler, A., Stampanoni, M., et al. (2008). Novel three-dimensional analysis tool for vascular trees indicates complete micro-networks, not single capillaries, as the angiogenic endpoint in mice overexpressing human VEGF(165) in the brain. Neuroimage 39, 1549-1558. doi: 10.1016/j.neuroimage.2007.10.054
-
(2008)
Neuroimage
, vol.39
, pp. 1549-1558
-
-
Heinzer, S.1
Kuhn, G.2
Krucker, T.3
Meyer, E.4
Ulmann-Schuler, A.5
Stampanoni, M.6
-
116
-
-
33847127375
-
The claudin gene family: Expression in normal and neoplas-tic tissues
-
doi: 10.1186/1471-2407-6-186
-
Hewitt, K. J., Agarwal, R., and Morin, P. J. (2006). The claudin gene family: expression in normal and neoplas-tic tissues. BMC Cancer 6:186. doi: 10.1186/1471-2407-6-186
-
(2006)
BMC Cancer
, vol.6
, pp. 186
-
-
Hewitt, K.J.1
Agarwal, R.2
Morin, P.J.3
-
117
-
-
33846604242
-
How common are the common neurologic disorders?
-
doi: 10. 1212/01.wnl.0000252807.38124.a3
-
Hirtz, D., Thurman, D. J., Gwinn-Hardy, K., Mohamed, M., Chaudhuri, A. R., and Zalutsky, R. (2007). How common are the common neurologic disorders? Neurology 68, 326-337. doi: 10. 1212/01.wnl.0000252807.38124.a3
-
(2007)
Neurology
, vol.68
, pp. 326-337
-
-
Hirtz, D.1
Thurman, D.J.2
Gwinn-Hardy, K.3
Mohamed, M.4
Chaudhuri, A.R.5
Zalutsky, R.6
-
118
-
-
0021239705
-
Endothelial proliferation in tumours and normal tissues: Continuous labelling studies
-
doi: 10.1038/bjc.1984.66
-
Hobson, B., and Denekamp, J. (1984). Endothelial proliferation in tumours and normal tissues: continuous labelling studies. Br. J. Cancer 49, 405-413. doi: 10.1038/bjc.1984.66
-
(1984)
Br. J. Cancer
, vol.49
, pp. 405-413
-
-
Hobson, B.1
Denekamp, J.2
-
119
-
-
0001586077
-
Body composition and energy needs during growth
-
eds F. Falkner and J. M. Tanner (Newyork, NY: Plenum
-
Holliday, M. A. (1986). "Body composition and energy needs during growth," in Human Growth: A Comprehensive Treatise, eds F. Falkner and J. M. Tanner (Newyork, NY: Plenum), 101-117.
-
(1986)
Human Growth: A Comprehensive Treatise
, pp. 101-117
-
-
Holliday, M.A.1
-
120
-
-
33845547792
-
Pathophysiology and therapy of experimental stroke
-
doi: 10.1007/s10571-006-9008-1
-
Hossmann, K. A. (2006). Pathophysiology and therapy of experimental stroke. Cell. Mol. Neurobiol. 26, 1057-1083. doi: 10.1007/s10571-006-9008-1
-
(2006)
Cell. Mol. Neurobiol
, vol.26
, pp. 1057-1083
-
-
Hossmann, K.A.1
-
121
-
-
38449084547
-
Determination of drug permeability and prediction of drug absorption in Caco-2 monolayers
-
doi: 10.1038/nprot.2007.303
-
Hubatsch, I., Ragnarsson, E. G., and Artursson, P. (2007). Determination of drug permeability and prediction of drug absorption in Caco-2 monolayers. Nat. Protoc. 2, 2111-2119. doi: 10.1038/nprot.2007.303
-
(2007)
Nat. Protoc
, vol.2
, pp. 2111-2119
-
-
Hubatsch, I.1
Ragnarsson, E.G.2
Artursson, P.3
-
122
-
-
2342614850
-
Neurovascular regulation in the normal brain and in Alzheimer's disease
-
doi: 10.1038/nrn1387
-
Iadecola, C. (2004). Neurovascular regulation in the normal brain and in Alzheimer's disease. Nat. Rev. Neurosci. 5, 347-360. doi: 10.1038/nrn1387
-
(2004)
Nat. Rev. Neurosci
, vol.5
, pp. 347-360
-
-
Iadecola, C.1
-
123
-
-
35548969443
-
Glial regulation of the cerebral microvasculature
-
doi: 10.1038/nn2003
-
Iadecola, C., and Nedergaard, M. (2007). Glial regulation of the cerebral microvasculature. Nat. Neurosci. 10, 1369-1376. doi: 10.1038/nn2003
-
(2007)
Nat. Neurosci
, vol.10
, pp. 1369-1376
-
-
Iadecola, C.1
Nedergaard, M.2
-
124
-
-
0038119637
-
Changes in human cerebral blood flow and cerebral blood volume during hypercapnia and hypocap-nia measured by positron emission tomography
-
doi: 10.1097/ 01.WCB.0000067721.64998.F5
-
Ito, H., Kanno, I., Ibaraki, M., Hatazawa, J., and Miura, S. (2003). Changes in human cerebral blood flow and cerebral blood volume during hypercapnia and hypocap-nia measured by positron emission tomography. J. Cereb. Blood Flow Metab. 23, 665-670. doi: 10.1097/ 01.WCB.0000067721.64998.F5
-
(2003)
J. Cereb. Blood Flow Metab
, vol.23
, pp. 665-670
-
-
Ito, H.1
Kanno, I.2
Ibaraki, M.3
Hatazawa, J.4
Miura, S.5
-
125
-
-
67650300497
-
Acquired immunodeficiency syndrome and the blood-brain barrier
-
doi: 10.1080/13550280902769764
-
Ivey, N. S., Maclean, A. G., and Lackner, A. A. (2009). Acquired immunodeficiency syndrome and the blood-brain barrier. J. Neurovirol. 15, 111-122. doi: 10.1080/13550280902769764
-
(2009)
J. Neurovirol
, vol.15
, pp. 111-122
-
-
Ivey, N.S.1
Maclean, A.G.2
Lackner, A.A.3
-
126
-
-
0023108382
-
Astrocytes induce blood brain barrier properties in endothelial cells
-
doi: 10.1038/325253a0
-
Janzer, R. C., and Raff, M. C. (1987). Astrocytes induce blood brain barrier properties in endothelial cells. Nature 325, 253-257. doi: 10.1038/325253a0
-
(1987)
Nature
, vol.325
, pp. 253-257
-
-
Janzer, R.C.1
Raff, M.C.2
-
127
-
-
80054761707
-
Mechanotransduction of shear in the endothelium: Basic studies and clinical implications
-
doi: 10.1177/1358863X11422109
-
Johnson, B. D., Mather, K. J., and Wallace, J. P. (2011). Mechanotransduction of shear in the endothelium: basic studies and clinical implications. Vasc. Med. 16, 365-377. doi: 10.1177/1358863X11422109
-
(2011)
Vasc. Med
, vol.16
, pp. 365-377
-
-
Johnson, B.D.1
Mather, K.J.2
Wallace, J.P.3
-
128
-
-
0033391684
-
The blood-brain barrier and cerebrovascular pathology in Alzheimer's disease
-
doi: 10.1111/j.1749-6632.1999.tb07821.x
-
Kalaria, R. N. (1999). The blood-brain barrier and cerebrovascular pathology in Alzheimer's disease. Ann. N.Y. Acad. Sci. 893, 113-125. doi: 10.1111/j.1749-6632.1999.tb07821.x
-
(1999)
Ann. N.Y. Acad. Sci
, vol.893
, pp. 113-125
-
-
Kalaria, R.N.1
-
129
-
-
0021357966
-
Adaptive regulation of wall shear stress optimizing vascular tree function
-
Kamiya, A., Bukhari, R., and Togawa, T. (1984). Adaptive regulation of wall shear stress optimizing vascular tree function. Bull. Math. Biol. 46, 127-137.
-
(1984)
Bull. Math. Biol
, vol.46
, pp. 127-137
-
-
Kamiya, A.1
Bukhari, R.2
Togawa, T.3
-
130
-
-
34249873787
-
Global and regional brain metabolic scaling and its functional consequences
-
doi: 10.1186/1741-7007-5-18
-
Karbowski, J. (2007). Global and regional brain metabolic scaling and its functional consequences. BMC Biol. 5:18. doi: 10.1186/1741-7007-5-18
-
(2007)
BMC Biol
, vol.5
, pp. 18
-
-
Karbowski, J.1
-
131
-
-
70350572388
-
Thermodynamic constraints on neural dimensions, firing rates, brain temperature and size
-
doi: 10.1007/s10827-009-0153-7
-
Karbowski, J. (2009). Thermodynamic constraints on neural dimensions, firing rates, brain temperature and size. J. Comput. Neurosci. 27, 415-436. doi: 10.1007/s10827-009-0153-7
-
(2009)
J. Comput. Neurosci
, vol.27
, pp. 415-436
-
-
Karbowski, J.1
-
132
-
-
80055099916
-
Scaling of brain metabolism and blood flow in relation to capillary and neural scaling
-
doi: 10.1371/journal.pone.0026709
-
Karbowski, J. (2011). Scaling of brain metabolism and blood flow in relation to capillary and neural scaling. PLoS ONE 6:e26709. doi: 10.1371/journal.pone.0026709
-
(2011)
PLoS ONE
, vol.6
-
-
Karbowski, J.1
-
133
-
-
0025803782
-
A method for the determination of cellular permeability coefficients and aqueous boundary-layer thickness in monolayers of intestinal epithelial (caco-2) cells grown in permeable filter chambers
-
doi: 10.1016/0378-5173(91)90067-X
-
Karlsson, J., and Artursson, P. (1991). A method for the determination of cellular permeability coefficients and aqueous boundary-layer thickness in monolayers of intestinal epithelial (caco-2) cells grown in permeable filter chambers. Int. J. Pharm. 71, 55-64. doi: 10.1016/0378-5173(91)90067-X
-
(1991)
Int. J. Pharm
, vol.71
, pp. 55-64
-
-
Karlsson, J.1
Artursson, P.2
-
134
-
-
0001653395
-
Thermodynamic analysis of the permeability of biological membranes to non-electrolytes
-
doi: 10.1016/0006-3002(58)90330-5
-
Kedem, O., and Katchalsky, A. (1958). Thermodynamic analysis of the permeability of biological membranes to non-electrolytes. Biochim. Biophys. Acta 27, 229-246. doi: 10.1016/0006-3002(58)90330-5
-
(1958)
Biochim. Biophys. Acta
, vol.27
, pp. 229-246
-
-
Kedem, O.1
Katchalsky, A.2
-
135
-
-
0024990661
-
Breakdown of the blood-brain-barrier precedes symptoms and other mri signs of new lesions in multiple-sclerosis -pathogenetic and clinical implications
-
doi: 10.1093/brain/113.5.1477
-
Kermode, A. G., Thompson, A. J., Tofts, P., Macmanus, D. G., Kendall, B. E., Kingsley, D. P. E., et al. (1990). Breakdown of the blood-brain-barrier precedes symptoms and other mri signs of new lesions in multiple-sclerosis -pathogenetic and clinical implications. Brain 113, 1477-1489. doi: 10.1093/brain/113.5.1477
-
(1990)
Brain
, vol.113
, pp. 1477-1489
-
-
Kermode, A.G.1
Thompson, A.J.2
Tofts, P.3
Macmanus, D.G.4
Kendall, B.E.5
Kingsley, D.P.E.6
-
136
-
-
62849101195
-
Recruitment of pericytes and astro-cytes is closely related to the formation of tight junction in developing retinal vessels
-
doi: 10.1002/jnr.21884
-
Kim, J. H., Kim, J. H., Yu, Y. S., Kim, D. H., and Kim, K. W. (2009). Recruitment of pericytes and astro-cytes is closely related to the formation of tight junction in developing retinal vessels. J. Neurosci. Res. 87, 653-659. doi: 10.1002/jnr.21884
-
(2009)
J. Neurosci. Res
, vol.87
, pp. 653-659
-
-
Kim, J.H.1
Kim, J.H.2
Yu, Y.S.3
Kim, D.H.4
Kim, K.W.5
-
137
-
-
33749525328
-
Innate response to focal necrotic injury inside the blood-brain barrier
-
Kim, J. V., and Dustin, M. L. (2006). Innate response to focal necrotic injury inside the blood-brain barrier. J. Immunol. 177, 5269-5277.
-
(2006)
J. Immunol
, vol.177
, pp. 5269-5277
-
-
Kim, J.V.1
Dustin, M.L.2
-
138
-
-
0035118510
-
Transport of opioids from the brain to the periphery by P-glycoprotein: Peripheral actions of central drugs
-
doi: 10.1038/85115
-
King, M., Su, W., Chang, A., Zuckerman, A., and Pasternak, G. W. (2001). Transport of opioids from the brain to the periphery by P-glycoprotein: peripheral actions of central drugs. Nat. Neurosci. 4, 268-274. doi: 10.1038/85115
-
(2001)
Nat. Neurosci
, vol.4
, pp. 268-274
-
-
King, M.1
Su, W.2
Chang, A.3
Zuckerman, A.4
Pasternak, G.W.5
-
139
-
-
84870657123
-
Extracellular sheets and tunnels modulate gluta-mate diffusion in hippocampal neu-ropil
-
doi: 10.1002/cne.23181
-
Kinney, J. P., Spacek, J., Bartol, T. M., Bajaj, C. L., Harris, K. M., and Sejnowski, T. J. (2013). Extracellular sheets and tunnels modulate gluta-mate diffusion in hippocampal neu-ropil. J. Comp. Neurol. 521, 448-464. doi: 10.1002/cne.23181
-
(2013)
J. Comp. Neurol
, vol.521
, pp. 448-464
-
-
Kinney, J.P.1
Spacek, J.2
Bartol, T.M.3
Bajaj, C.L.4
Harris, K.M.5
Sejnowski, T.J.6
-
140
-
-
84957355538
-
Body size and metabolic rate
-
Kleiber, M. (1947). Body size and metabolic rate. Physiol. Rev. 27, 511-541.
-
(1947)
Physiol. Rev
, vol.27
, pp. 511-541
-
-
Kleiber, M.1
-
141
-
-
0023005833
-
Interdependency of local capillary density, blood-flow, and metabolism in rat brains
-
Klein, B., Kuschinsky, W., Schrock, H., and Vetterlein, F. (1986). Interdependency of local capillary density, blood-flow, and metabolism in rat brains. Am. J. Physiol. 251, H1333-H1340.
-
(1986)
Am. J. Physiol
, vol.251
-
-
Klein, B.1
Kuschinsky, W.2
Schrock, H.3
Vetterlein, F.4
-
142
-
-
13144255682
-
Blood-brain barrier dysfunction in parkinsonian midbrain in vivo
-
doi: 10.1002/ana.20369
-
Kortekaas, R., Leenders, K. L., Van Oostrom, J. C., Vaalburg, W., Bart, J., Willemsen, A. T., et al. (2005). Blood-brain barrier dysfunction in parkinsonian midbrain in vivo. Ann. Neurol. 57, 176-179. doi: 10.1002/ana.20369
-
(2005)
Ann. Neurol
, vol.57
, pp. 176-179
-
-
Kortekaas, R.1
Leenders, K.L.2
van Oostrom, J.C.3
Vaalburg, W.4
Bart, J.5
Willemsen, A.T.6
-
143
-
-
58149119716
-
Volume flow and wall shear stress quantification in the human conjunc-tival capillaries and post-capillary venules in vivo
-
Koutsiaris, A. G., Tachmitzi, S. V., Batis, N., Kotoula, M. G., Karabatsas, C. H., Tsironi, E., et al. (2007). Volume flow and wall shear stress quantification in the human conjunc-tival capillaries and post-capillary venules in vivo. Biorheology 44, 375-386.
-
(2007)
Biorheology
, vol.44
, pp. 375-386
-
-
Koutsiaris, A.G.1
Tachmitzi, S.V.2
Batis, N.3
Kotoula, M.G.4
Karabatsas, C.H.5
Tsironi, E.6
-
144
-
-
67249143522
-
Structure and function of extracellular claudin domains
-
doi: 10.1111/j.1749-6632.2009.04057.x
-
Krause, G., Winkler, L., Piehl, C., Blasig, I., Piontek, J., and Muller, S. L. (2009). Structure and function of extracellular claudin domains. Ann. N.Y. Acad. Sci. 1165, 34-43. doi: 10.1111/j.1749-6632.2009.04057.x
-
(2009)
Ann. N.Y. Acad. Sci
, vol.1165
, pp. 34-43
-
-
Krause, G.1
Winkler, L.2
Piehl, C.3
Blasig, I.4
Piontek, J.5
Muller, S.L.6
-
145
-
-
62349101606
-
Microvessel length density, total length, and length per neuron in five subcortical regions in schizophrenia
-
doi: 10.1007/s00401-009-0482-7
-
Kreczmanski, P., Heinsen, H., Mantua, V., Woltersdorf, F., Masson, T., Ulfig, N., et al. (2009). Microvessel length density, total length, and length per neuron in five subcortical regions in schizophrenia. Acta Neuropathol. 117, 409-421. doi: 10.1007/s00401-009-0482-7
-
(2009)
Acta Neuropathol
, vol.117
, pp. 409-421
-
-
Kreczmanski, P.1
Heinsen, H.2
Mantua, V.3
Woltersdorf, F.4
Masson, T.5
Ulfig, N.6
-
146
-
-
21344472611
-
Stereological studies of capillary length density in the frontal cortex of schizophrenics
-
doi: 10.1007/s00401-005-1003-y
-
Kreczmanski, P., Schmidt-Kastner, R., Heinsen, H., Steinbusch, H. W. M., Hof, P. R., and Schmitz, C. (2005). Stereological studies of capillary length density in the frontal cortex of schizophrenics. Acta Neuropathol. 109, 510-518. doi: 10.1007/s00401-005-1003-y
-
(2005)
Acta Neuropathol
, vol.109
, pp. 510-518
-
-
Kreczmanski, P.1
Schmidt-Kastner, R.2
Heinsen, H.3
Steinbusch, H.W.M.4
Hof, P.R.5
Schmitz, C.6
-
147
-
-
79958128131
-
Specification of transplantable astroglial subtypes from human pluripotent stem cells
-
doi: 10.1038/nbt.1877
-
Krencik, R., Weick, J. P., Liu, Y., Zhang, Z. J., and Zhang, S. C. (2011). Specification of transplantable astroglial subtypes from human pluripotent stem cells. Nat. Biotechnol. 29, 528-534. doi: 10.1038/nbt.1877
-
(2011)
Nat. Biotechnol
, vol.29
, pp. 528-534
-
-
Krencik, R.1
Weick, J.P.2
Liu, Y.3
Zhang, Z.J.4
Zhang, S.C.5
-
148
-
-
10344259085
-
The cerebral vasculature as a therapeutic target for neurological disorders and the role of shear stress in vascular homeostatis and pathophysiol-ogy
-
doi: 10.1179/016164104X3789
-
Krizanac-Bengez, L., Mayberg, M. R., and Janigro, D. (2004). The cerebral vasculature as a therapeutic target for neurological disorders and the role of shear stress in vascular homeostatis and pathophysiol-ogy. Neurol. Res. 26, 846-853. doi: 10.1179/016164104X3789
-
(2004)
Neurol. Res
, vol.26
, pp. 846-853
-
-
Krizanac-Bengez, L.1
Mayberg, M.R.2
Janigro, D.3
-
149
-
-
77951218143
-
Activity-dependent layer-specific changes in the extracellular chloride concentration and chloride driving force in the rat hippocampus
-
. doi: 10.1152/jn.00497.2009
-
Kroeger, D., Tamburri, A., Amzica, F., and Sik, A. (2010). Activity-dependent layer-specific changes in the extracellular chloride concentration and chloride driving force in the rat hippocampus. J. Neurophysiol. 103, 1905-1914. doi: 10.1152/jn.00497.2009
-
(2010)
J. Neurophysiol
, vol.103
, pp. 1905-1914
-
-
Kroeger, D.1
Tamburri, A.2
Amzica, F.3
Sik, A.4
-
150
-
-
73349140140
-
CNS pericytes: Concepts, misconceptions, and a way out
-
doi: 10.1002/glia.20898
-
Krueger, M., and Bechmann, I. (2010). CNS pericytes: concepts, misconceptions, and a way out. Glia 58, 1-10. doi: 10.1002/glia.20898
-
(2010)
Glia
, vol.58
, pp. 1-10
-
-
Krueger, M.1
Bechmann, I.2
-
151
-
-
0017647476
-
Quantitative structure-activity relationships. 7. The bilinear model, a new model for nonlinear dependence of biological activity on hydrophobic character
-
doi: 10.1021/jm00215a002
-
Kubinyi, H. (1977). Quantitative structure-activity relationships. 7. The bilinear model, a new model for nonlinear dependence of biological activity on hydrophobic character. J. Med. Chem. 20, 625-629. doi: 10.1021/jm00215a002
-
(1977)
J. Med. Chem
, vol.20
, pp. 625-629
-
-
Kubinyi, H.1
-
152
-
-
84863334894
-
Analytical and biological methods for probing the blood-brain barrier
-
doi: 10.1146/annurev-anchem-062011-143002
-
Kuhnline Sloan, C. D., Nandi, P., Linz, T. H., Aldrich, J. V., Audus, K. L., and Lunte, S. M. (2012). Analytical and biological methods for probing the blood-brain barrier. Annu. Rev. Anal. Chem. (Palo Alto Calif) 5, 505-531. doi: 10.1146/annurev-anchem-062011-143002
-
(2012)
Annu. Rev. Anal. Chem. (Palo Alto Calif)
, vol.5
, pp. 505-531
-
-
Kuhnline Sloan, C.D.1
Nandi, P.2
Linz, T.H.3
Aldrich, J.V.4
Audus, K.L.5
Lunte, S.M.6
-
154
-
-
0035212257
-
Drug trans porters in the central nervous system: Brain barriers and brain parenchyma considerations
-
Lee, G., Dallas, S., Hong, M., and Bendayan, R. (2001). Drug trans porters in the central nervous system: brain barriers and brain parenchyma considerations. Pharmacol. Rev. 53, 569-596.
-
(2001)
Pharmacol. Rev
, vol.53
, pp. 569-596
-
-
Lee, G.1
Dallas, S.2
Hong, M.3
Bendayan, R.4
-
155
-
-
0037703253
-
SSeCKS regulates angiogen-esis and tight junction formation in blood-brain barrier
-
doi: 10.1038/nm889
-
Lee, S. W., Kim, W. J., Choi, Y. K., Song, H. S., Son, M. J., Gelman, I. H., et al. (2003). SSeCKS regulates angiogen-esis and tight junction formation in blood-brain barrier. Nat. Med. 9, 900-906. doi: 10.1038/nm889
-
(2003)
Nat. Med
, vol.9
, pp. 900-906
-
-
Lee, S.W.1
Kim, W.J.2
Choi, Y.K.3
Song, H.S.4
Son, M.J.5
Gelman, I.H.6
-
156
-
-
0037452922
-
The cost of cortical computation
-
doi: 10.1016/S0960-9822(03)00135-0
-
Lennie, P. (2003). The cost of cortical computation. Curr. Biol. 13, 493-497. doi: 10.1016/S0960-9822(03)00135-0
-
(2003)
Curr. Biol
, vol.13
, pp. 493-497
-
-
Lennie, P.1
-
157
-
-
0022160653
-
The elongation and orientation of cultured endothelial-cells in response to shear-stress
-
doi: 10.1115/1.3138567
-
Levesque, M. J., and Nerem, R. M. (1985). The elongation and orientation of cultured endothelial-cells in response to shear-stress. J. Biomech. Eng. 107, 341-347. doi: 10.1115/1.3138567
-
(1985)
J. Biomech. Eng
, vol.107
, pp. 341-347
-
-
Levesque, M.J.1
Nerem, R.M.2
-
158
-
-
80051730491
-
Fluids and barriers of the CNS: A historical viewpoint
-
doi: 10.1186/2045-8118-8-2
-
Liddelow, S. A. (2011). Fluids and barriers of the CNS: a historical viewpoint. Fluids Barriers CNS 8, 2. doi: 10.1186/2045-8118-8-2
-
(2011)
Fluids Barriers CNS
, vol.8
, pp. 2
-
-
Liddelow, S.A.1
-
159
-
-
0035289779
-
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
-
doi: 10.1016/S0169-409X(00)00129-0
-
Lipinski, C. A., Lombardo, F., Dominy, B. W., and Feeney, P. J. (2001). Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv. Drug Deliv. Rev. 46, 3-26. doi: 10.1016/S0169-409X(00)00129-0
-
(2001)
Adv. Drug Deliv. Rev
, vol.46
, pp. 3-26
-
-
Lipinski, C.A.1
Lombardo, F.2
Dominy, B.W.3
Feeney, P.J.4
-
160
-
-
84864874302
-
Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells
-
doi: 10.1038/nbt.2247
-
Lippmann, E. S., Azarin, S. M., Kay, J. E., Nessler, R. A., Wilson, H. K., Al-Ahmad, A., et al. (2012). Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells. Nat. Biotechnol. 30, 783-791. doi: 10.1038/nbt.2247
-
(2012)
Nat. Biotechnol
, vol.30
, pp. 783-791
-
-
Lippmann, E.S.1
Azarin, S.M.2
Kay, J.E.3
Nessler, R.A.4
Wilson, H.K.5
Al-Ahmad, A.6
-
161
-
-
0034624286
-
Structural alterations of tight junctions are associated with loss of polarity in stroke-prone spontaneously hypertensive rat blood-brain barrier endothelial cells
-
doi: 10.1016/S0006-8993(00)02954-1
-
Lippoldt, A., Kniesel, U., Liebner, S., Kalbacher, H., Kirsch, T., Wolburg, H., et al. (2000). Structural alterations of tight junctions are associated with loss of polarity in stroke-prone spontaneously hypertensive rat blood-brain barrier endothelial cells. Brain Res. 885, 251-261. doi: 10.1016/S0006-8993(00)02954-1
-
(2000)
Brain Res
, vol.885
, pp. 251-261
-
-
Lippoldt, A.1
Kniesel, U.2
Liebner, S.3
Kalbacher, H.4
Kirsch, T.5
Wolburg, H.6
-
162
-
-
1642579680
-
Development of a computational approach to predict blood-brain barrier permeability
-
doi: 10.1124/dmd.32.1.132
-
Liu, X., Tu, M., Kelly, R. S., Chen, C., and Smith, B. J. (2004). Development of a computational approach to predict blood-brain barrier permeability. Drug Metab. Dispos. 32, 132-139. doi: 10.1124/dmd.32.1.132
-
(2004)
Drug Metab. Dispos
, vol.32
, pp. 132-139
-
-
Liu, X.1
Tu, M.2
Kelly, R.S.3
Chen, C.4
Smith, B.J.5
-
163
-
-
84984763363
-
Mechanisms, challenges and opportunities in stroke
-
doi: 10.1038/nrn1106
-
Lo, E. H., Dalkara, T., and Moskowitz, M. A. (2003). Mechanisms, challenges and opportunities in stroke. Nat. Rev. Neurosci. 4, 399-415. doi: 10.1038/nrn1106
-
(2003)
Nat. Rev. Neurosci
, vol.4
, pp. 399-415
-
-
Lo, E.H.1
Dalkara, T.2
Moskowitz, M.A.3
-
164
-
-
0031943571
-
Regulation of the movement of solutes across tight junctions
-
doi: 10.1146/annurev.physiol.60.1.143
-
Madara, J. L. (1998). Regulation of the movement of solutes across tight junctions. Annu. Rev. Physiol. 60, 143-159. doi: 10.1146/annurev.physiol.60.1.143
-
(1998)
Annu. Rev. Physiol
, vol.60
, pp. 143-159
-
-
Madara, J.L.1
-
165
-
-
0030006215
-
Mechanism of endothelial cell shape change and cytoskele-tal remodeling in response to fluid shear stress
-
Malek, A. M., and Izumo, S. (1996). Mechanism of endothelial cell shape change and cytoskele-tal remodeling in response to fluid shear stress. J. Cell Sci. 109, 713-726.
-
(1996)
J. Cell Sci
, vol.109
, pp. 713-726
-
-
Malek, A.M.1
Izumo, S.2
-
167
-
-
59749101668
-
The effects of blood-brain barrier disruption on glial cell function in multiple sclerosis
-
doi: 10.1042/BST0370329
-
McQuaid, S., Cunnea, P., McMahon, J., and Fitzgerald, U. (2009). The effects of blood-brain barrier disruption on glial cell function in multiple sclerosis. Biochem. Soc. Trans. 37, 329-331. doi: 10.1042/BST0370329
-
(2009)
Biochem. Soc. Trans
, vol.37
, pp. 329-331
-
-
McQuaid, S.1
Cunnea, P.2
McMahon, J.3
Fitzgerald, U.4
-
168
-
-
42149161677
-
Altered morphology and 3D architecture of brain vasculature in a mouse model for Alzheimer's disease
-
doi: 10.1073/pnas. 0709788105
-
Meyer, E. P., Ulmann-Schuler, A., Staufenbiel, M., and Krucker, T. (2008). Altered morphology and 3D architecture of brain vasculature in a mouse model for Alzheimer's disease. Proc. Natl. Acad. Sci. U.S.A. 105, 3587-3592. doi: 10.1073/pnas. 0709788105
-
(2008)
Proc. Natl. Acad. Sci. U.S.A
, vol.105
, pp. 3587-3592
-
-
Meyer, E.P.1
Ulmann-Schuler, A.2
Staufenbiel, M.3
Krucker, T.4
-
169
-
-
0347525827
-
Confocal imaging of xenobiotic transport across the blood-brain barrier
-
doi: 10.1002/jez.a.10313
-
Miller, D. S. (2003). Confocal imaging of xenobiotic transport across the blood-brain barrier. J. Exp. Zool. A Comp. Exp. Biol. 300A, 84-90. doi: 10.1002/jez.a.10313
-
(2003)
J. Exp. Zool. a Comp. Exp. Biol
, pp. 84-90
-
-
Miller, D.S.1
-
170
-
-
0344961161
-
Blood-brain barrier disruption in multiple sclerosis
-
doi: 10.1191/1352458503ms965oa
-
Minagar, A., and Alexander, J. S. (2003). Blood-brain barrier disruption in multiple sclerosis. Mult. Scler. 9, 540-549. doi: 10.1191/1352458503ms965oa
-
(2003)
Mult. Scler
, vol.9
, pp. 540-549
-
-
Minagar, A.1
Alexander, J.S.2
-
171
-
-
0033523758
-
Endothelial claudin: Claudin-5/TMVCF constitutes tight junction strands in endothelial cells
-
doi: 10.1083/jcb.147.1.185
-
Morita, K., Sasaki, H., Furuse, M., and Tsukita, S. (1999). Endothelial claudin: claudin-5/TMVCF constitutes tight junction strands in endothelial cells. J. Cell Biol. 147, 185-194. doi: 10.1083/jcb.147.1.185
-
(1999)
J. Cell Biol
, vol.147
, pp. 185-194
-
-
Morita, K.1
Sasaki, H.2
Furuse, M.3
Tsukita, S.4
-
172
-
-
77955487488
-
The science of stroke: Mechanisms in search of treatments
-
doi: 10.1016/j.neuron.2010.07.002
-
Moskowitz, M. A., Lo, E. H., and Iadecola, C. (2010). The science of stroke: mechanisms in search of treatments. Neuron 67, 181-198. doi: 10.1016/j.neuron.2010.07.002
-
(2010)
Neuron
, vol.67
, pp. 181-198
-
-
Moskowitz, M.A.1
Lo, E.H.2
Iadecola, C.3
-
173
-
-
0642342131
-
Morphological and molecular properties of cellular components of normal cerebral vessels
-
ed S. Nag (New Jersey, NJ: Humana Press
-
Nag, S. (2003). "Morphological and molecular properties of cellular components of normal cerebral vessels," in The Blood-Brain Barrier: Biological and Research Protocols, ed S. Nag (New Jersey, NJ: Humana Press), 3-36.
-
(2003)
The Blood-Brain Barrier: Biological and Research Protocols
, pp. 3-36
-
-
Nag, S.1
-
174
-
-
60949110463
-
A new blood-brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes
-
doi: 10.1016/j.neuint.2008.12.002
-
Nakagawa, S., Deli, M. A., Kawaguchi, H., Shimizudani, T., Shimono, T., Kittel, A., et al. (2009). A new blood-brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes. Neurochem. Int. 54, 253-263. doi: 10.1016/j.neuint.2008.12.002
-
(2009)
Neurochem. Int
, vol.54
, pp. 253-263
-
-
Nakagawa, S.1
Deli, M.A.2
Kawaguchi, H.3
Shimizudani, T.4
Shimono, T.5
Kittel, A.6
-
175
-
-
82555187010
-
Energetics and the evolution of human brain size
-
doi: 10.1038/nature10629
-
Navarrete, A., van Schaik, C. P., and Isler, K. (2011). Energetics and the evolution of human brain size. Nature 480, 91-93. doi: 10.1038/nature10629
-
(2011)
Nature
, vol.480
, pp. 91-93
-
-
Navarrete, A.1
van Schaik, C.P.2
Isler, K.3
-
176
-
-
0019359912
-
Vascular endothelial morphology as an indicator of the pattern of blood-flow
-
doi: 10.1115/1.3138275
-
Nerem, R. M., Levesque, M. J., and Cornhill, J. F. (1981). Vascular endothelial morphology as an indicator of the pattern of blood-flow. J. Biomech. Eng. 103, 172-176. doi: 10.1115/1.3138275
-
(1981)
J. Biomech. Eng
, vol.103
, pp. 172-176
-
-
Nerem, R.M.1
Levesque, M.J.2
Cornhill, J.F.3
-
177
-
-
37149034911
-
Strategies to advance translational research into brain barriers
-
doi: 10.1016/S1474-4422(07)70326-5
-
Neuwelt, E., Abbott, N., Abrey, L., Banks, W. A., Blakley, B., Davis, T., et al. (2008). Strategies to advance translational research into brain barriers. Lancet Neurol. 7, 84-96. doi: 10.1016/S1474-4422(07)70326-5
-
(2008)
Lancet Neurol
, vol.7
, pp. 84-96
-
-
Neuwelt, E.1
Abbott, N.2
Abrey, L.3
Banks, W.A.4
Blakley, B.5
Davis, T.6
-
178
-
-
79951922143
-
Engaging neu-roscience to advance translational research in brain barrier biology
-
doi: 10.1038/nrn2995
-
Neuwelt, E. A., Bauer, B., Fahlke, C., Fricker, G., Iadecola, C., Janigro, D., et al. (2011). Engaging neu-roscience to advance translational research in brain barrier biology. Nat. Rev. Neurosci. 12, 169-182. doi: 10.1038/nrn2995
-
(2011)
Nat. Rev. Neurosci
, vol.12
, pp. 169-182
-
-
Neuwelt, E.A.1
Bauer, B.2
Fahlke, C.3
Fricker, G.4
Iadecola, C.5
Janigro, D.6
-
179
-
-
71849084133
-
Impaired blood-brain and blood-spinal cord barriers in mutant SOD1-linked ALS rat
-
doi: 10.1016/j.brainres.2009.09.018
-
Nicaise, C., Mitrecic, D., Demetter, P., De Decker, R., Authelet, M., Boom, A., et al. (2009). Impaired blood-brain and blood-spinal cord barriers in mutant SOD1-linked ALS rat. Brain Res. 1301, 152-162. doi: 10.1016/j.brainres.2009.09.018
-
(2009)
Brain Res
, vol.1301
, pp. 152-162
-
-
Nicaise, C.1
Mitrecic, D.2
Demetter, P.3
de Decker, R.4
Authelet, M.5
Boom, A.6
-
180
-
-
0034946945
-
Diffusion and related transport mechanisms in brain tissue
-
doi: 10.1088/0034-4885/64/7/202
-
Nicholson, C. (2001). Diffusion and related transport mechanisms in brain tissue. Rep. Prog. Phys. 64, 815-884. doi: 10.1088/0034-4885/64/7/202
-
(2001)
Rep. Prog. Phys
, vol.64
, pp. 815-884
-
-
Nicholson, C.1
-
181
-
-
0037648580
-
Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice
-
doi: 10.1083/jcb.200302070
-
Nitta, T., Hata, M., Gotoh, S., Seo, Y., Sasaki, H., Hashimoto, N., et al. (2003). Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice. J. Cell Biol. 161, 653-660. doi: 10.1083/jcb.200302070
-
(2003)
J. Cell Biol
, vol.161
, pp. 653-660
-
-
Nitta, T.1
Hata, M.2
Gotoh, S.3
Seo, Y.4
Sasaki, H.5
Hashimoto, N.6
-
182
-
-
63849175251
-
Uniquely hominid features of adult human astrocytes
-
doi: 10.1523/JNEUROSCI.4707-08.2009
-
Oberheim, N. A., Takano, T., Han, X., He, W., Lin, J. H. C., Wang, F., et al. (2009). Uniquely hominid features of adult human astrocytes. J. Neurosci. 29, 3276-3287. doi: 10.1523/JNEUROSCI.4707-08.2009
-
(2009)
J. Neurosci
, vol.29
, pp. 3276-3287
-
-
Oberheim, N.A.1
Takano, T.2
Han, X.3
He, W.4
Lin, J.H.C.5
Wang, F.6
-
183
-
-
33750924816
-
The blood-brain barrier and epilepsy
-
doi: 10.1111/j.1528-1167.2006.00817.x
-
Oby, E., and Janigro, D. (2006). The blood-brain barrier and epilepsy. Epilepsia 47, 1761-1774. doi: 10.1111/j.1528-1167.2006.00817.x
-
(2006)
Epilepsia
, vol.47
, pp. 1761-1774
-
-
Oby, E.1
Janigro, D.2
-
184
-
-
20444459153
-
Remodeling of vascular endothe-lial cells exposed to fluid shear stress: Experimental and numerical approach
-
doi: 10.1016/j.fluiddyn.2004.08.005
-
Ohashi, T., and Sato, M. (2005). Remodeling of vascular endothe-lial cells exposed to fluid shear stress: experimental and numerical approach. Fluid Dyn. Res. 37, 40-59. doi: 10.1016/j.fluiddyn.2004.08.005
-
(2005)
Fluid Dyn. Res
, vol.37
, pp. 40-59
-
-
Ohashi, T.1
Sato, M.2
-
185
-
-
0018237164
-
Lower limits of cerebrovascular permeability to nonelectrolytes in the conscious rat
-
Ohno, K., Pettigrew, K. D., and Rapoport, S. I. (1978). Lower limits of cerebrovascular permeability to nonelectrolytes in the conscious rat. Am. J. Physiol. 235, H299-H307.
-
(1978)
Am. J. Physiol
, vol.235
-
-
Ohno, K.1
Pettigrew, K.D.2
Rapoport, S.I.3
-
186
-
-
34547632714
-
Contribution of carrier-mediated transport systems to the blood-brain barrier as a supporting and protecting interface for the brain; importance for CNS drug discovery and development
-
doi: 10.1007/s11095-007-9374-5
-
Ohtsuki, S., and Terasaki, T. (2007). Contribution of carrier-mediated transport systems to the blood-brain barrier as a supporting and protecting interface for the brain; importance for CNS drug discovery and development. Pharm. Res. 24, 1745-1758. doi: 10.1007/s11095-007-9374-5
-
(2007)
Pharm. Res
, vol.24
, pp. 1745-1758
-
-
Ohtsuki, S.1
Terasaki, T.2
-
187
-
-
9344244100
-
Molecular mechanisms of brain tumor edema
-
doi: 10.1016/j.neuroscience.2004.05.044
-
Papadopoulos, M. C., Saadoun, S., Binder, D. K., Manley, G. T., Krishna, S., and Verkman, A. S. (2004). Molecular mechanisms of brain tumor edema. Neuroscience 129, 1011-1020. doi: 10.1016/j.neuroscience.2004.05.044
-
(2004)
Neuroscience
, vol.129
, pp. 1011-1020
-
-
Papadopoulos, M.C.1
Saadoun, S.2
Binder, D.K.3
Manley, G.T.4
Krishna, S.5
Verkman, A.S.6
-
188
-
-
17844363452
-
Vascular wall shear stress: Basic principles and methods
-
Papaioannou, T. G., and Stefanadis, C. (2005). Vascular wall shear stress: basic principles and methods. Hellenic J. Cardiol. 46, 9-15.
-
(2005)
Hellenic J. Cardiol
, vol.46
, pp. 9-15
-
-
Papaioannou, T.G.1
Stefanadis, C.2
-
189
-
-
0031959341
-
CNS drug design based on principles of blood-brain barrier transport
-
doi: 10.1046/j.1471-4159.1998.70051781.x
-
Pardridge, W. M. (1998). CNS drug design based on principles of blood-brain barrier transport. J. Neurochem. 70, 1781-1792. doi: 10.1046/j.1471-4159.1998.70051781.x
-
(1998)
J. Neurochem
, vol.70
, pp. 1781-1792
-
-
Pardridge, W.M.1
-
190
-
-
0042899083
-
Blood-brain barrier drug targeting: The future of brain drug development
-
doi: 10.1124/mi.3.2.90
-
Pardridge, W. M. (2003). Blood-brain barrier drug targeting: the future of brain drug development. Mol. Interv. 3, 90-105. doi: 10.1124/mi.3.2.90
-
(2003)
Mol. Interv
, vol.3
, pp. 90-105
-
-
Pardridge, W.M.1
-
191
-
-
12344273726
-
The blood-brain barrier: Bottleneck in brain drug development
-
doi: 10.1602/neurorx.2.1.3
-
Pardridge, W. M. (2005). The blood-brain barrier: bottleneck in brain drug development. NeuroRx 2, 3-14. doi: 10.1602/neurorx.2.1.3
-
(2005)
NeuroRx
, vol.2
, pp. 3-14
-
-
Pardridge, W.M.1
-
192
-
-
33748452503
-
Molecular Trojan horses for blood-brain barrier drug delivery
-
doi: 10.1016/j.coph.2006.06.001
-
Pardridge, W. M. (2006). Molecular Trojan horses for blood-brain barrier drug delivery. Curr. Opin. Pharmacol. 6, 494-500. doi: 10.1016/j.coph.2006.06.001
-
(2006)
Curr. Opin. Pharmacol
, vol.6
, pp. 494-500
-
-
Pardridge, W.M.1
-
193
-
-
47749105642
-
Re-engineering biopharmaceuticals for delivery to brain with molecular Trojan horses
-
doi: 10.1021/bc800148t
-
Pardridge, W. M. (2008). Re-engineering biopharmaceuticals for delivery to brain with molecular Trojan horses. Bioconjug. Chem. 19, 1327-1338. doi: 10.1021/bc800148t
-
(2008)
Bioconjug. Chem
, vol.19
, pp. 1327-1338
-
-
Pardridge, W.M.1
-
194
-
-
77949375780
-
Biopharmaceutical drug targeting to the brain
-
doi: 10.3109/10611860903548354
-
Pardridge, W. M. (2010). Biopharmaceutical drug targeting to the brain. J. Drug Target. 18, 157-167. doi: 10.3109/10611860903548354
-
(2010)
J. Drug Target
, vol.18
, pp. 157-167
-
-
Pardridge, W.M.1
-
195
-
-
0025329190
-
Comparison of in vitro and in vivo models of drug transcytosis through the blood-brain barrier
-
Pardridge, W. M., Triguero, D., Yang, J., and Cancilla, P. A. (1990). Comparison of in vitro and in vivo models of drug transcytosis through the blood-brain barrier. J. Pharmacol. Exp. Ther. 253, 884-891.
-
(1990)
J. Pharmacol. Exp. Ther
, vol.253
, pp. 884-891
-
-
Pardridge, W.M.1
Triguero, D.2
Yang, J.3
Cancilla, P.A.4
-
196
-
-
79960770976
-
Three-dimensional imaging of the mouse neurovascula-ture with magnetic resonance microscopy
-
doi: 10.1371/journal.pone.0022643
-
Pathak, A. P., Kim, E., Zhang, J., and Jones, M. V. (2011). Three-dimensional imaging of the mouse neurovascula-ture with magnetic resonance microscopy. PLoS ONE 6:e22643. doi: 10.1371/journal.pone.0022643
-
(2011)
PLoS ONE
, vol.6
-
-
Pathak, A.P.1
Kim, E.2
Zhang, J.3
Jones, M.V.4
-
197
-
-
33749860102
-
Bidirectional control of CNS capillary diameter by peri-cytes
-
doi: 10.1038/nature05193
-
Peppiatt, C. M., Howarth, C., Mobbs, P., and Attwell, D. (2006). Bidirectional control of CNS capillary diameter by peri-cytes. Nature 443, 700-704. doi: 10.1038/nature05193
-
(2006)
Nature
, vol.443
, pp. 700-704
-
-
Peppiatt, C.M.1
Howarth, C.2
Mobbs, P.3
Attwell, D.4
-
198
-
-
33745094734
-
Rho-mediated regulation of tight junctions during monocyte migration across the blood-brain barrier in HIV-1 encephalitis (HIVE)
-
doi: 10.1182/blood-2005-11-4721
-
Persidsky, Y., Heilman, D., Haorah, J., Zelivyanskaya, M., Persidsky, R., Weber, G. A., et al. (2006). Rho-mediated regulation of tight junctions during monocyte migration across the blood-brain barrier in HIV-1 encephalitis (HIVE). Blood 107, 4770-4780. doi: 10.1182/blood-2005-11-4721
-
(2006)
Blood
, vol.107
, pp. 4770-4780
-
-
Persidsky, Y.1
Heilman, D.2
Haorah, J.3
Zelivyanskaya, M.4
Persidsky, R.5
Weber, G.A.6
-
199
-
-
67849083569
-
PET radiotrac-ers: Crossing the blood-brain barrier and surviving metabolism
-
doi: 10.1016/j.tips.2009.05.005
-
Pike, V. W. (2009). PET radiotrac-ers: crossing the blood-brain barrier and surviving metabolism. Trends Pharmacol. Sci. 30, 431-440. doi: 10.1016/j.tips.2009.05.005
-
(2009)
Trends Pharmacol. Sci
, vol.30
, pp. 431-440
-
-
Pike, V.W.1
-
200
-
-
38049166110
-
Formation of tight junction: Determinants of homophilic interaction between classic claudins
-
doi: 10.1096/fj.07-8319com
-
Piontek, J., Winkler, L., Wolburg, H., Muller, S. L., Zuleger, N., Piehl, C., et al. (2008). Formation of tight junction: determinants of homophilic interaction between classic claudins. FASEB J. 22, 146-158. doi: 10.1096/fj.07-8319com
-
(2008)
FASEB J
, vol.22
, pp. 146-158
-
-
Piontek, J.1
Winkler, L.2
Wolburg, H.3
Muller, S.L.4
Zuleger, N.5
Piehl, C.6
-
201
-
-
82555191282
-
Evolution big brains explained
-
doi: 10.1038/480043a
-
Potts, R. (2011). Evolution big brains explained. Nature 480, 43-44. doi: 10.1038/480043a
-
(2011)
Nature
, vol.480
, pp. 43-44
-
-
Potts, R.1
-
202
-
-
33748361335
-
Brain work and brain imaging
-
doi: 10.1146/annurev. neuro.29.051605.112819
-
Raichle, M. E., and Mintun, M. A. (2006). Brain work and brain imaging. Annu. Rev. Neurosci. 29, 449-476. doi: 10.1146/annurev. neuro.29.051605.112819
-
(2006)
Annu. Rev. Neurosci
, vol.29
, pp. 449-476
-
-
Raichle, M.E.1
Mintun, M.A.2
-
203
-
-
0018398457
-
Drug entry into the brain
-
doi: 10.1016/0006-8993(79)90546-8
-
Rapoport, S. I., Ohno, K., and Pettigrew, K. D. (1979). Drug entry into the brain. Brain Res. 172, 354-359. doi: 10.1016/0006-8993(79)90546-8
-
(1979)
Brain Res
, vol.172
, pp. 354-359
-
-
Rapoport, S.I.1
Ohno, K.2
Pettigrew, K.D.3
-
204
-
-
0014109002
-
Fine structural localization of a blood-brain barrier to exogenous peroxidase
-
doi: 10.1083/jcb. 34.1.207
-
Reese, T. S., and Karnovsky, M. J. (1967). Fine structural localization of a blood-brain barrier to exogenous peroxidase. J. Cell Biol. 34, 207-217. doi: 10.1083/jcb. 34.1.207
-
(1967)
J. Cell Biol
, vol.34
, pp. 207-217
-
-
Reese, T.S.1
Karnovsky, M.J.2
-
205
-
-
0642372727
-
An overview of in vitro techniques for blood brain barrier studies
-
The Blood Brain Barrier, ed S. Nag (Totowa, NJ: Humana), doi: 10.1385/1-59259-419-0:307
-
Reichel, A., Begley, D. J., and Abbottt, N. J. (2003). "An overview of in vitro techniques for blood brain barrier studies," in Methods in Molecular Medicine, Vol. 89: The Blood Brain Barrier, ed S. Nag (Totowa, NJ: Humana), 307-324. doi: 10.1385/1-59259-419-0:307
-
(2003)
Methods In Molecular Medicine
, vol.89
, pp. 307-324
-
-
Reichel, A.1
Begley, D.J.2
Abbottt, N.J.3
-
206
-
-
30344467212
-
Molecular and cellular mechanisms of pharmacoresistance in epilepsy
-
doi: 10.1093/brain/awh682
-
Remy, S., and Beck, H. (2006). Molecular and cellular mechanisms of pharmacoresistance in epilepsy. Brain 129, 18-35. doi: 10.1093/brain/awh682
-
(2006)
Brain
, vol.129
, pp. 18-35
-
-
Remy, S.1
Beck, H.2
-
207
-
-
13344292421
-
Transport of potassium-42 from blood to tissue in isolated mammalian skeletal muscles
-
Renkin, E. M. (1959). Transport of potassium-42 from blood to tissue in isolated mammalian skeletal muscles. Am. J. Physiol. 197, 1205-1210.
-
(1959)
Am. J. Physiol
, vol.197
, pp. 1205-1210
-
-
Renkin, E.M.1
-
208
-
-
32344446371
-
Development of the blood-brain barrier: A historical point of view
-
doi: 10.1002/ar.b.20087
-
Ribatti, D., Nico, B., Crivellato, E., and Artico, M. (2006). Development of the blood-brain barrier: a historical point of view. Anat. Rec. B New Anat. 289, 3-8. doi: 10.1002/ar.b.20087
-
(2006)
Anat. Rec. B New Anat
, vol.289
, pp. 3-8
-
-
Ribatti, D.1
Nico, B.2
Crivellato, E.3
Artico, M.4
-
209
-
-
0035815988
-
A functional assay for detection of the mitox-antrone resistance protein, MXR (ABCG2)
-
doi: 10.1016/S0005-2736(01)00308-X
-
Robey, R. W., Honjo, Y., Van De Laar, A., Miyake, K., Regis, J. T., Litman, T., et al. (2001). A functional assay for detection of the mitox-antrone resistance protein, MXR (ABCG2). Biochim. Biophys. Acta 1512, 171-182. doi: 10.1016/S0005-2736(01)00308-X
-
(2001)
Biochim. Biophys. Acta
, vol.1512
, pp. 171-182
-
-
Robey, R.W.1
Honjo, Y.2
Van De Laar, A.3
Miyake, K.4
Regis, J.T.5
Litman, T.6
-
210
-
-
18144382265
-
Evolution of the brain and intelligence
-
doi: 10.1016/j.tics.2005.03.005
-
Roth, G., and Dicke, U. (2005). Evolution of the brain and intelligence. Trends Cogn. Sci. (Regul. Ed.) 9, 250-257. doi: 10.1016/j.tics.2005.03.005
-
(2005)
Trends Cogn. Sci. (Regul. Ed.)
, vol.9
, pp. 250-257
-
-
Roth, G.1
Dicke, U.2
-
211
-
-
0024589689
-
Extracellular-matrix molecules that influence neural development
-
doi: 10.1146/ annurev.ne.12.030189.002423
-
Sanes, J. R. (1989). Extracellular-matrix molecules that influence neural development. Annu. Rev. Neurosci. 12, 491-516. doi: 10.1146/ annurev.ne.12.030189.002423
-
(1989)
Annu. Rev. Neurosci
, vol.12
, pp. 491-516
-
-
Sanes, J.R.1
-
212
-
-
0032678857
-
Expression of the multidrug-resistance P-glycoprotein (Pgp, MDR-1) by endothelial cells of the neovasculature in central nervous system tumors
-
doi: 10.1007/BF02478898
-
Sawada, T., Kato, Y., Sakayori, N., Takekawa, Y., and Kobayashi, M. (1999). Expression of the multidrug-resistance P-glycoprotein (Pgp, MDR-1) by endothelial cells of the neovasculature in central nervous system tumors. Brain Tumor Pathol. 16, 23-27. doi: 10.1007/BF02478898
-
(1999)
Brain Tumor Pathol
, vol.16
, pp. 23-27
-
-
Sawada, T.1
Kato, Y.2
Sakayori, N.3
Takekawa, Y.4
Kobayashi, M.5
-
213
-
-
0032754657
-
Microvessel organization and structure in experimental brain tumors: Microvessel populations with distinctive structural and functional properties
-
doi: 10.1006/mvre.1999. 2188
-
Schlageter, K. E., Molnar, P., Lapin, G. D., and Groothuis, D. R. (1999). Microvessel organization and structure in experimental brain tumors: microvessel populations with distinctive structural and functional properties. Microvasc. Res. 58, 312-328. doi: 10.1006/mvre.1999. 2188
-
Microvasc. Res
, vol.58
, pp. 312-328
-
-
Schlageter, K.E.1
Molnar, P.2
Lapin, G.D.3
Groothuis, D.R.4
-
214
-
-
27244461958
-
P-glycoprotein-mediated secretion of a fluorescent cyclosporin analogue by teleost renal proximal tubules
-
Schramm, U., Fricker, G., Wenger, R., and Miller, D. S. (1995). P-glycoprotein-mediated secretion of a fluorescent cyclosporin analogue by teleost renal proximal tubules. Am. J. Physiol. 268, F46-F52.
-
(1995)
Am. J. Physiol
, vol.268
-
-
Schramm, U.1
Fricker, G.2
Wenger, R.3
Miller, D.S.4
-
215
-
-
4544312032
-
Lasting blood-brain barrier disruption induces epileptic focus in the rat somatosensory cortex
-
doi: 10.1523/JNEUROSCI.1751-04.2004
-
Seiffert, E., Dreier, J. P., Ivens, S., Bechmann, I., Tomkins, O., Heinemann, U., et al. (2004). Lasting blood-brain barrier disruption induces epileptic focus in the rat somatosensory cortex. J. Neurosci. 24, 7829-7836. doi: 10.1523/JNEUROSCI.1751-04.2004
-
(2004)
J. Neurosci
, vol.24
, pp. 7829-7836
-
-
Seiffert, E.1
Dreier, J.P.2
Ivens, S.3
Bechmann, I.4
Tomkins, O.5
Heinemann, U.6
-
216
-
-
0024325094
-
The Application of bovine brain microvessel endothelial-cell mono-layers grown onto polycarbonate membranes in vitro to estimate the potential permeability of solutes through the blood-brain barrier
-
doi: 10.1023/A:1015913817221
-
Shah, M. V., Audus, K. L., and Borchardt, R. T. (1989). The Application of bovine brain microvessel endothelial-cell mono-layers grown onto polycarbonate membranes in vitro to estimate the potential permeability of solutes through the blood-brain barrier. Pharm. Res. 6, 624-627. doi: 10.1023/A:1015913817221
-
(1989)
Pharm. Res
, vol.6
, pp. 624-627
-
-
Shah, M.V.1
Audus, K.L.2
Borchardt, R.T.3
-
217
-
-
79951775751
-
Tight junction pore and leak pathways: A dynamic duo
-
doi: 10.1146/annurev-physiol-012110-142150
-
Shen, L., Weber, C. R., Raleigh, D. R., Yu, D., and Turner, J. R. (2011). Tight junction pore and leak pathways: a dynamic duo. Annu. Rev. Physiol. 73, 283-309. doi: 10.1146/annurev-physiol-012110-142150
-
(2011)
Annu. Rev. Physiol
, vol.73
, pp. 283-309
-
-
Shen, L.1
Weber, C.R.2
Raleigh, D.R.3
Yu, D.4
Turner, J.R.5
-
218
-
-
0027319870
-
Pericyte physiology
-
Shepro, D., and Morel, N. M. (1993). Pericyte physiology. FASEB J. 7, 1031-1038.
-
(1993)
FASEB J
, vol.7
, pp. 1031-1038
-
-
Shepro, D.1
Morel, N.M.2
-
219
-
-
77954862661
-
Blood-brain barrier breakdown as a therapeutic target in traumatic brain injury
-
doi: 10.1038/nrneurol. 2010.74
-
Shlosberg, D., Benifla, M., Kaufer, D., and Friedman, A. (2010). Blood-brain barrier breakdown as a therapeutic target in traumatic brain injury. Nat. Rev. Neurol. 6, 393-403. doi: 10.1038/nrneurol. 2010.74
-
(2010)
Nat. Rev. Neurol
, vol.6
, pp. 393-403
-
-
Shlosberg, D.1
Benifla, M.2
Kaufer, D.3
Friedman, A.4
-
220
-
-
3242737585
-
Energetic basis of brain activity: Implications for neuroimaging
-
doi: 10.1016/j.tins.2004.06.005
-
Shulman, R. G., Rothman, D. L., Behar, K. L., and Hyder, F. (2004). Energetic basis of brain activity: implications for neuroimaging. Tre n ds Neu rosc i. 27, 489-495. doi: 10.1016/j.tins.2004.06.005
-
(2004)
Tre N Ds Neu Rosc I
, vol.27
, pp. 489-495
-
-
Shulman, R.G.1
Rothman, D.L.2
Behar, K.L.3
Hyder, F.4
-
221
-
-
0014514618
-
Isolation of highly purified human and bovine brain endothelial cells and nuclei and their phospholipid composition
-
doi: 10.1007/BF02532638
-
Siakotos, A. N., Rouser, G., and Fleischer, S. (1969). Isolation of highly purified human and bovine brain endothelial cells and nuclei and their phospholipid composition. Lipids 4, 234-239. doi: 10.1007/BF02532638
-
(1969)
Lipids
, vol.4
, pp. 234-239
-
-
Siakotos, A.N.1
Rouser, G.2
Fleischer, S.3
-
222
-
-
34147098912
-
Human astrocytes/astrocyte- conditioned medium and shear stress enhance the barrier properties of human brain microvascular endothelial cells
-
doi: 10.1016/j.brainres. 2007.02.029
-
Siddharthan, V., Kim, Y. V., Liu, S., and Kim, K. S. (2007). Human astrocytes/astrocyte- conditioned medium and shear stress enhance the barrier properties of human brain microvascular endothelial cells. Brain Res. 1147, 39-50. doi: 10.1016/j.brainres. 2007.02.029
-
(2007)
Brain Res
, vol.1147
, pp. 39-50
-
-
Siddharthan, V.1
Kim, Y.V.2
Liu, S.3
Kim, K.S.4
-
223
-
-
0023268809
-
Molecular-sieving characteristics of the cultured endothelial monolayer
-
doi: 10.1002/jcp.1041320115
-
Siflinger-Birnboim, A., Delvecchio, P. J., Cooper, J. A., Blumenstock, F. A., Shepard, J. M., and Malik, A. B. (1987). Molecular-sieving characteristics of the cultured endothelial monolayer. J. Cell. Physiol. 132, 111-117. doi: 10.1002/jcp.1041320115
-
(1987)
J. Cell. Physiol
, vol.132
, pp. 111-117
-
-
Siflinger-Birnboim, A.1
Delvecchio, P.J.2
Cooper, J.A.3
Blumenstock, F.A.4
Shepard, J.M.5
Malik, A.B.6
-
224
-
-
0022567611
-
The pericyte - a review
-
doi: 10.1016/0040-8166(86)90026-1
-
Sims, D. E. (1986). The pericyte - a review. Tissue Cell 18, 153-174. doi: 10.1016/0040-8166(86)90026-1
-
(1986)
Tissue Cell
, vol.18
, pp. 153-174
-
-
Sims, D.E.1
-
225
-
-
84863334894
-
Analytical and biological methods for probing the blood-brain barrier
-
eds R. G. Cooks and E. S. Yeung (Palo Alto, CA: Annual Reviews
-
Sloan, C. D. K., Nandi, P., Linz, T. H., Aldrich, J. V., Audus, K. L., and Lunte, S. M. (2012). "Analytical and biological methods for probing the blood-brain barrier," in Annual Review of Analytical Chemistry, Vol. 5, eds R. G. Cooks and E. S. Yeung (Palo Alto, CA: Annual Reviews), 505-531.
-
(2012)
Annual Review of Analytical Chemistry
, vol.5
, pp. 505-531
-
-
Sloan, C.D.K.1
Nandi, P.2
Linz, T.H.3
Aldrich, J.V.4
Audus, K.L.5
Lunte, S.M.6
-
226
-
-
0642311333
-
A review of blood-brain barrier transport techniques
-
ed S. Nag (Totowa, NJ: Humana Press
-
Smith, Q. R. (2003). "A review of blood-brain barrier transport techniques," in The Blood-Brain Barrier: Biology and Research Protocols, ed S. Nag (Totowa, NJ: Humana Press), 193-208.
-
(2003)
The Blood-Brain Barrier: Biology and Research Protocols
, pp. 193-208
-
-
Smith, Q.R.1
-
227
-
-
0642311330
-
In situ brain perfusion technique
-
ed. S. Nag (Totowa, NJ: Humana Press
-
Smith, Q. R., and Allen, D. D. (2003). "In situ brain perfusion technique," in The Blood-Brain Barrier: Biology and Research Protocols, ed. S. Nag (Totowa, NJ: Humana Press), 209-218.
-
(2003)
The Blood-Brain Barrier: Biology and Research Protocols
, pp. 209-218
-
-
Smith, Q.R.1
Allen, D.D.2
-
228
-
-
0022930655
-
Kinetics of amino acid transport at the blood-brain barrier studied using an in situ brain perfu-sion technique
-
doi: 10.1111/j.1749-6632.1986.tb27150.x
-
Smith, Q. R., and Takasato, Y. (1986). Kinetics of amino acid transport at the blood-brain barrier studied using an in situ brain perfu-sion technique. Ann. N.Y. Acad. Sci. 481, 186-201. doi: 10.1111/j.1749-6632.1986.tb27150.x
-
(1986)
Ann. N.Y. Acad. Sci
, vol.481
, pp. 186-201
-
-
Smith, Q.R.1
Takasato, Y.2
-
229
-
-
85031915964
-
The energetics of encephalization in early hominids
-
doi: 10.1007/978-1-4020-9699-0_2
-
Snodgrass, J. J., Leonard, W. R., and Robertson, M. L. (2009). The energetics of encephalization in early hominids. Evol. Hominin Diets 15-29. doi: 10.1007/978-1-4020-9699-0_2
-
(2009)
Evol. Hominin Diets
, vol.15-29
-
-
Snodgrass, J.J.1
Leonard, W.R.2
Robertson, M.L.3
-
230
-
-
84875576366
-
Genetic mouse models to study blood-brain barrier development and function
-
doi: 10.1186/2045-8118-10-3
-
Sohet, F., and Daneman, R. (2013). Genetic mouse models to study blood-brain barrier development and function. Fluids Barriers CNS 10, 3. doi: 10.1186/2045-8118-10-3
-
(2013)
Fluids Barriers CNS
, vol.10
, pp. 3
-
-
Sohet, F.1
Daneman, R.2
-
231
-
-
17544375423
-
Experimental closed head injury: Analysis of neurological outcome, blood-brain barrier dysfunction, intracranial neutrophil infiltration, and neuronal cell death in mice deficient in genes for pro-inflammatory cytokines
-
Stahel, P. F., Shohami, E., Younis, F. M., Kariya, K., Otto, V. I., Lenzlinger, P. M., et al. (2000). Experimental closed head injury: analysis of neurological outcome, blood-brain barrier dysfunction, intracranial neutrophil infiltration, and neuronal cell death in mice deficient in genes for pro-inflammatory cytokines. J. Cereb. Blood Flow Metab. 20, 369-380. doi: 10.1097/00004647-200002000-00019
-
(2000)
J. Cereb. Blood Flow Metab
, vol.20
, pp. 369-380
-
-
Stahel, P.F.1
Shohami, E.2
Younis, F.M.3
Kariya, K.4
Otto, V.I.5
Lenzlinger, P.M.6
-
232
-
-
0035821601
-
Experimental and computational screening models for the prediction of intestinal drug absorption
-
doi: 10.1021/jm001101a
-
Stenberg, P., Norinder, U., Luthman, K., and Artursson, P. (2001). Experimental and computational screening models for the prediction of intestinal drug absorption. J. Med. Chem. 44, 1927-1937. doi: 10.1021/jm001101a
-
(2001)
J. Med. Chem
, vol.44
, pp. 1927-1937
-
-
Stenberg, P.1
Norinder, U.2
Luthman, K.3
Artursson, P.4
-
233
-
-
0030917425
-
Selective expression of adhesion molecules on human brain microvascular endothe-lial cells
-
doi: 10.1016/S0165-5728 (97)00036-2
-
Stins, M. F., Gilles, F., and Kim, K. S. (1997). Selective expression of adhesion molecules on human brain microvascular endothe-lial cells. J. Neuroimmunol. 76, 81-90. doi: 10.1016/S0165-5728 (97)00036-2
-
(1997)
J. Neuroimmunol
, vol.76
, pp. 81-90
-
-
Stins, M.F.1
Gilles, F.2
Kim, K.S.3
-
234
-
-
34250744722
-
Central nervous system drug disposition: The relationship between in situ brain permeability and brain free fraction
-
doi: 10.1124/jpet.107.121525
-
Summerfield, S. G., Read, K., Begley, D. J., Obradovic, T., Hidalgo, I. J., Coggon, S., et al. (2007). Central nervous system drug disposition: the relationship between in situ brain permeability and brain free fraction. J. Pharmacol. Exp. Ther. 322, 205-213. doi: 10.1124/jpet.107.121525
-
(2007)
J. Pharmacol. Exp. Ther
, vol.322
, pp. 205-213
-
-
Summerfield, S.G.1
Read, K.2
Begley, D.J.3
Obradovic, T.4
Hidalgo, I.J.5
Coggon, S.6
-
235
-
-
33644756715
-
Improving the in vitro prediction of in vivo central nervous system penetration: Integrating permeability, p-glycoprotein efflux, and free fractions in blood and brain
-
doi: 10.1124/jpet.105.092916
-
Summerfield, S. G., Stevens, A. J., Cutler, L., Del Carmen Osuna, M., Hammond, B., Tang, S.-P., et al. (2006). Improving the in vitro prediction of in vivo central nervous system penetration: integrating permeability, p-glycoprotein efflux, and free fractions in blood and brain. J. Pharmacol. Exp. Ther. 316, 1282-1290. doi: 10.1124/jpet.105.092916
-
(2006)
J. Pharmacol. Exp. Ther
, vol.316
, pp. 1282-1290
-
-
Summerfield, S.G.1
Stevens, A.J.2
Cutler, L.3
Del Carmen, O.M.4
Hammond, B.5
Tang, S.-P.6
-
236
-
-
55949130305
-
Diffusion in brain extracellular space
-
doi: 10.1152/physrev. 00027.2007
-
Sykova, E., and Nicholson, C. (2008). Diffusion in brain extracellular space. Physiol. Rev. 88, 1277-1340. doi: 10.1152/physrev. 00027.2007
-
(2008)
Physiol. Rev
, vol.88
, pp. 1277-1340
-
-
Sykova, E.1
Nicholson, C.2
-
237
-
-
48649101326
-
Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5
-
doi: 10.1038/ncb1752
-
Taddei, A., Giampietro, C., Conti, A., Orsenigo, F., Breviario, F., Pirazzoli, V., et al. (2008). Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5. Nat. Cell Biol. 10, 923-934. doi: 10.1038/ncb1752
-
(2008)
Nat. Cell Biol
, vol.10
, pp. 923-934
-
-
Taddei, A.1
Giampietro, C.2
Conti, A.3
Orsenigo, F.4
Breviario, F.5
Pirazzoli, V.6
-
238
-
-
31544456102
-
Astrocyte-mediated control of cerebral blood flow
-
doi: 10.1038/nn1623
-
Takano, T., Tian, G. F., Peng, W., Lou, N., Libionka, W., Han, X., et al. (2006). Astrocyte-mediated control of cerebral blood flow. Nat. Neurosci. 9, 260-267. doi: 10.1038/nn1623
-
(2006)
Nat. Neurosci
, vol.9
, pp. 260-267
-
-
Takano, T.1
Tian, G.F.2
Peng, W.3
Lou, N.4
Libionka, W.5
Han, X.6
-
239
-
-
0000545811
-
An in situ brain perfu-sion technique to study cerebrovas-cular transport in the rat
-
Takasato, Y., Rapoport, S. I., and Smith, Q. R. (1984). An in situ brain perfu-sion technique to study cerebrovas-cular transport in the rat. Am. J. Physiol. 247, H484-H493.
-
(1984)
Am. J. Physiol
, vol.247
-
-
Takasato, Y.1
Rapoport, S.I.2
Smith, Q.R.3
-
240
-
-
77954341974
-
Shear stress and the endothelial transport barrier
-
doi: 10.1093/cvr/cvq146
-
Tarbell, J. M. (2010). Shear stress and the endothelial transport barrier. Cardiovasc. Res. 87, 320-330. doi: 10.1093/cvr/cvq146
-
(2010)
Cardiovasc Res
, vol.87
, pp. 320-330
-
-
Tarbell, J.M.1
-
241
-
-
0035684325
-
Lipid polarity in brain capillary endothelial cells
-
doi: 10.3109/10623320109051566
-
Tewes, B. J., and Galla, H. J. (2001). Lipid polarity in brain capillary endothelial cells. Endothelium 8, 207-220. doi: 10.3109/10623320109051566
-
(2001)
Endothelium
, vol.8
, pp. 207-220
-
-
Tewes, B.J.1
Galla, H.J.2
-
242
-
-
79960898997
-
The impact of pericytes on the blood-brain barrier integrity depends critically on the pericyte differentiation stage
-
doi: 10.1016/j.biocel. 2011.05.002
-
Thanabalasundaram, G., Schneidewind, J., Pieper, C., and Galla, H. J. (2011). The impact of pericytes on the blood-brain barrier integrity depends critically on the pericyte differentiation stage. Int. J. Biochem. Cell Biol. 43, 1284-1293. doi: 10.1016/j.biocel. 2011.05.002
-
(2011)
Int. J. Biochem. Cell Biol
, vol.43
, pp. 284-1293
-
-
Thanabalasundaram, G.1
Schneidewind, J.2
Pieper, C.3
Galla, H.J.4
-
243
-
-
25844453453
-
Diffusion measurements for drug design
-
doi: 10.1038/nmat1489
-
Thorne, R. G., Hrabetova, S., and Nicholson, C. (2005). Diffusion measurements for drug design. Nat. Mater. 4, 713-713. doi: 10.1038/nmat1489
-
(2005)
Nat. Mater
, vol.4
, pp. 713
-
-
Thorne, R.G.1
Hrabetova, S.2
Nicholson, C.3
-
244
-
-
33645791896
-
In vivo diffusion analysis with quantum dots and dextrans predicts the width of brain extracellular space
-
doi: 10.1073/pnas.0509425103
-
Thorne, R. G., and Nicholson, C. (2006). In vivo diffusion analysis with quantum dots and dextrans predicts the width of brain extracellular space. Proc. Natl. Acad. Sci. U.S.A. 103, 5567-5572. doi: 10.1073/pnas.0509425103
-
(2006)
Proc. Natl. Acad. Sci. U.S.A
, vol.103
, pp. 5567-5572
-
-
Thorne, R.G.1
Nicholson, C.2
-
245
-
-
0037209457
-
Expression and adhesive properties of basement membrane proteins in cerebral capillary endothelial cell cultures
-
doi: 10.1007/s00441-002-0604-1
-
Tilling, T., Engelbertz, C., Decker, S., Korte, D., Huwel, S., and Galla, H. J. (2002). Expression and adhesive properties of basement membrane proteins in cerebral capillary endothelial cell cultures. Cell Tissue Res. 310, 19-29. doi: 10.1007/s00441-002-0604-1
-
(2002)
Cell Tissue Res
, vol.310
, pp. 19-29
-
-
Tilling, T.1
Engelbertz, C.2
Decker, S.3
Korte, D.4
Huwel, S.5
Galla, H.J.6
-
246
-
-
0031843634
-
Basement membrane proteins influence brain capillary endothelial barrier function in vitro
-
doi: 10.1046/j.1471-4159.1998.71031151.x
-
Tilling, T., Korte, D., Hoheisel, D., and Galla, H. J. (1998). Basement membrane proteins influence brain capillary endothelial barrier function in vitro. J. Neurochem. 71, 1151-1157. doi: 10.1046/j.1471-4159.1998.71031151.x
-
(1998)
J. Neurochem
, vol.71
, pp. 1151-1157
-
-
Tilling, T.1
Korte, D.2
Hoheisel, D.3
Galla, H.J.4
-
247
-
-
3042697038
-
Hyaluronan: From extracellular glue to pericellular cue
-
doi: 10.1038/nrc1391
-
Toole, B. P. (2004). Hyaluronan: from extracellular glue to pericellular cue. Nat. Rev. Cancer 4, 528-539. doi: 10.1038/nrc1391
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 528-539
-
-
Toole, B.P.1
-
248
-
-
3843082996
-
Exact kinetic analysis of passive transport across a polarized confluent MDCK cell mono-layer modeled as a single barrier
-
doi: 10.1002/jps.20105
-
Tran, T. T., Mittal, A., Gales, T., Maleeff, B., Aldinger, T., Polli, J. W., et al. (2004). Exact kinetic analysis of passive transport across a polarized confluent MDCK cell mono-layer modeled as a single barrier. J. Pharm. Sci. 93, 2108-2123. doi: 10.1002/jps.20105
-
(2004)
J. Pharm. Sci
, vol.93
, pp. 2108-2123
-
-
Tran, T.T.1
Mittal, A.2
Gales, T.3
Maleeff, B.4
Aldinger, T.5
Polli, J.W.6
-
249
-
-
0033168966
-
Occludin and claudins in tight-junction strands: Leading or supporting players?
-
doi: 10.1016/S0962-8924(99)01578-0
-
Tsukita, S., and Furuse, M. (1999). Occludin and claudins in tight-junction strands: leading or supporting players? Tre n ds Ce ll B iol. 9, 268-273. doi: 10.1016/S0962-8924(99)01578-0
-
(1999)
Tre N Ds Ce Ll B Iol
, vol.9
, pp. 268-273
-
-
Tsukita, S.1
Furuse, M.2
-
250
-
-
0035320037
-
Multifunctional strands in tight junctions
-
doi: 10.1038/35067088
-
Tsukita, S., Furuse, M., and Itoh, M. (2001). Multifunctional strands in tight junctions. Nat. Rev. Mol. Cell Biol. 2, 285-293. doi: 10.1038/35067088
-
(2001)
Nat. Rev. Mol. Cell Biol
, vol.2
, pp. 285-293
-
-
Tsukita, S.1
Furuse, M.2
Itoh, M.3
-
251
-
-
0037392850
-
Morphine blood-brain barrier transport is influenced by probenecid co-administration
-
doi: 10.1023/A:1023250900462
-
Tunblad, K., Jonsson, E. N., and Hammarlund-Udenaes, M. (2003). Morphine blood-brain barrier transport is influenced by probenecid co-administration. Pharm. Res. 20, 618-623. doi: 10.1023/A:1023250900462
-
(2003)
Pharm. Res
, vol.20
, pp. 618-623
-
-
Tunblad, K.1
Jonsson, E.N.2
Hammarlund-Udenaes, M.3
-
252
-
-
0020405449
-
Blood viscosity, mass transport, and thrombo-genesis
-
Turitto, V. T. (1982). Blood viscosity, mass transport, and thrombo-genesis. Prog. Hemost. Thromb. 6, 139-177.
-
(1982)
Prog. Hemost. Thromb
, vol.6
, pp. 139-177
-
-
Turitto, V.T.1
-
253
-
-
0037085254
-
Signaling properties of hyaluronan receptors
-
doi: 10.1074/jbc.R100038200
-
Turley, E. A., Noble, P. W., and Bourguignon, L. Y. (2002). Signaling properties of hyaluronan receptors. J. Biol. Chem. 277, 4589-4592. doi: 10.1074/jbc.R100038200
-
(2002)
J. Biol. Chem
, vol.277
, pp. 4589-4592
-
-
Turley, E.A.1
Noble, P.W.2
Bourguignon, L.Y.3
-
254
-
-
69549095908
-
The surface-anchored NanA protein promotes pneumococcal brain endothelial cell invasion
-
doi: 10.1084/jem.20090386
-
Uchiyama, S., Carlin, A. F., Khosravi, A., Weiman, S., Banerjee, A., Quach, D., et al. (2009). The surface-anchored NanA protein promotes pneumococcal brain endothelial cell invasion. J. Exp. Med. 206, 1845-1852. doi: 10.1084/jem.20090386
-
(2009)
J. Exp. Med
, vol.206
, pp. 1845-1852
-
-
Uchiyama, S.1
Carlin, A.F.2
Khosravi, A.3
Weiman, S.4
Banerjee, A.5
Quach, D.6
-
255
-
-
70349687243
-
Mechanisms of the penetration of blood-borne substances into the brain
-
doi: 10.2174/157015909788848901
-
Ueno, M. (2009). Mechanisms of the penetration of blood-borne substances into the brain. Curr. Neuropharmacol. 7, 142-149. doi: 10.2174/157015909788848901
-
(2009)
Curr. Neuropharmacol
, vol.7
, pp. 142-149
-
-
Ueno, M.1
-
256
-
-
0035951508
-
Control of synapse number by glia
-
doi: 10.1126/science.291. 5504.657
-
Ullian, E. M., Sapperstein, S. K., Christopherson, K. S., and Barres, B. A. (2001). Control of synapse number by glia. Science 291, 657-661. doi: 10.1126/science.291. 5504.657
-
(2001)
Science
, vol.291
, pp. 657-661
-
-
Ullian, E.M.1
Sapperstein, S.K.2
Christopherson, K.S.3
Barres, B.A.4
-
257
-
-
0025994730
-
Microdialysis- principles and applications for studies in animals and man
-
doi: 10.1111/j.1365-2796.1991.tb00459.x
-
Ungerstedt, U. (1991). Microdialysis- principles and applications for studies in animals and man. J. Intern. Med. 230, 365-373. doi: 10.1111/j.1365-2796.1991.tb00459.x
-
(1991)
J. Intern. Med
, vol.230
, pp. 365-373
-
-
Ungerstedt, U.1
-
258
-
-
23044435896
-
Astrocytes, from brain glue to communication elements: The revolution continues
-
doi: 10.1038/nrn1722
-
Volterra, A., and Meldolesi, J. (2005). Astrocytes, from brain glue to communication elements: the revolution continues. Nat. Rev. Neurosci. 6, 626-640. doi: 10.1038/nrn1722
-
(2005)
Nat. Rev. Neurosci
, vol.6
, pp. 626-640
-
-
Volterra, A.1
Meldolesi, J.2
-
259
-
-
77956237647
-
Constitutive androstane receptor-mediated up-regulation of atp-driven xenobiotic efflux transporters at the blood-brain barrier
-
doi: 10.1124/mol.110.063685
-
Wang, X., Sykes, D. B., and Miller, D. S. (2010). Constitutive androstane receptor-mediated up-regulation of atp-driven xenobiotic efflux transporters at the blood-brain barrier. Mol. Pharmacol. 78, 376-383. doi: 10.1124/mol.110.063685
-
(2010)
Mol. Pharmacol
, vol.78
, pp. 376-383
-
-
Wang, X.1
Sykes, D.B.2
Miller, D.S.3
-
260
-
-
0344121272
-
Determination of lipophilicity and its use as a predictor of blood-brain barrier penetration of molecular imaging agents
-
doi: 10.1016/j.mibio.2003.09.014
-
Waterhouse, R. N. (2003). Determination of lipophilicity and its use as a predictor of blood-brain barrier penetration of molecular imaging agents. Mol. Imaging Biol. 5, 376-389. doi: 10.1016/j.mibio.2003.09.014
-
(2003)
Mol. Imaging Biol
, vol.5
, pp. 376-389
-
-
Waterhouse, R.N.1
-
261
-
-
33751074192
-
Biomarkers indicative of blood-brain barrier disruption in multiple sclerosis
-
doi: 10.1155/2006/709869
-
Waubant, E. (2006). Biomarkers indicative of blood-brain barrier disruption in multiple sclerosis. Dis. Markers 22, 235-244. doi: 10.1155/2006/709869
-
(2006)
Dis. Markers
, vol.22
, pp. 235-244
-
-
Waubant, E.1
-
262
-
-
4544311402
-
Selective decrease in para- cellular conductance of tight junctions: Role of the first extra cellular domain of claudin-5
-
doi: 10.1128/MCB.24.19.8408-8417.2004
-
Wen, H., Watry, D. D., Marcondes, M. C., and Fox, H. S. (2004). Selective decrease in para- cellular conductance of tight junctions: role of the first extra cellular domain of claudin-5. Mol. Cell. Biol. 24, 8408-8417. doi: 10.1128/MCB.24.19.8408-8417.2004
-
(2004)
Mol Cell Biol
, vol.24
, pp. 8408-8417
-
-
Wen, H.1
Watry, D.D.2
Marcondes, M.C.3
Fox, H.S.4
-
263
-
-
0028242843
-
High lipophilicity decreases drug transport across intestinal epithelial-cells
-
Wils, P., Warnery, A., Phungba, V., Legrain, S., and Scherman, D. (1994). High lipophilicity decreases drug transport across intestinal epithelial-cells. J. Pharmacol. Exp. Ther. 269, 654-658.
-
(1994)
J. Pharmacol. Exp. Ther
, vol.269
, pp. 654-658
-
-
Wils, P.1
Warnery, A.2
Phungba, V.3
Legrain, S.4
Scherman, D.5
-
264
-
-
80055014830
-
Central nervous system pericytes in health and disease
-
doi: 10.1038/nn.2946
-
Winkler, E. A., Bell, R. D., and Zlokovic, B. V. (2011). Central nervous system pericytes in health and disease. Nat. Neurosci. 14, 1398-1405. doi: 10.1038/nn.2946
-
(2011)
Nat. Neurosci
, vol.14
, pp. 1398-1405
-
-
Winkler, E.A.1
Bell, R.D.2
Zlokovic, B.V.3
-
265
-
-
0036627211
-
Tight junctions of the blood-brain barrier: Development, composition and regulation
-
doi: 10.1016/S1537-1891(02)00200-8
-
Wolburg, H., and Lippoldt, A. (2002). Tight junctions of the blood-brain barrier: development, composition and regulation. Vascul. Pharmacol. 38, 323-337. doi: 10.1016/S1537-1891(02)00200-8
-
(2002)
Vascul. Pharmacol
, vol.38
, pp. 323-337
-
-
Wolburg, H.1
Lippoldt, A.2
-
266
-
-
0034024027
-
Lecticans: Organizers of the brain extracellular matrix
-
doi: 10.1007/PL00000690
-
Yamaguchi, Y. (2000). Lecticans: organizers of the brain extracellular matrix. Cell. Mol. Life Sci. 57, 276-289. doi: 10.1007/PL00000690
-
(2000)
Cell. Mol. Life Sci
, vol.57
, pp. 276-289
-
-
Yamaguchi, Y.1
-
267
-
-
0030990079
-
In vitro permeability across Caco2 cells (colonic) can predict in vivo (small intestinal) absorption in man - Fact or myth
-
doi: 10.1023/A:1012102522787
-
Yee, S. Y. (1997). In vitro permeability across Caco2 cells (colonic) can predict in vivo (small intestinal) absorption in man - Fact or myth. Pharm. Res. 14, 763-766. doi: 10.1023/A:1012102522787
-
(1997)
Pharm. Res
, vol.14
, pp. 763-766
-
-
Yee, S.Y.1
-
268
-
-
0344983259
-
In vitro trans-monolayer permeability calculations: Often forgotten assumptions
-
doi: 10.1016/S1359-6446 (03)02873-3
-
Youdim, K. A., Avdeef, A., and Abbott, N. J. (2003). In vitro trans-monolayer permeability calculations: often forgotten assumptions. Drug Discov. Today 8, 997-1003. doi: 10.1016/S1359-6446 (03)02873-3
-
(2003)
Drug Discov. Today
, vol.8
, pp. 997-1003
-
-
Youdim, K.A.1
Avdeef, A.2
Abbott, N.J.3
-
269
-
-
1242338756
-
Flavonoid permeability across an in situ model of the blood-brain barrier
-
doi: 10.1016/j. freeradbiomed.2003.11.023
-
Youdim, K. A., Qaiser, M. Z., Begley, D. J., Rice-Evans, C. A., and Abbott, N. J. (2004). Flavonoid permeability across an in situ model of the blood-brain barrier. Free Radic. Biol. Med. 36, 592-604. doi: 10.1016/j. freeradbiomed.2003.11.023
-
(2004)
Free Radic. Biol. Med
, vol.36
, pp. 592-604
-
-
Youdim, K.A.1
Qaiser, M.Z.2
Begley, D.J.3
Rice-Evans, C.A.4
Abbott, N.J.5
-
270
-
-
67349191878
-
Assessment of blood-brain barrier permeability using the in situ mouse brain perfu-sion technique
-
doi: 10.1007/s11095-009-9876-4
-
Zhao, R., Kalvass, J. C., and Pollack, G. M. (2009). Assessment of blood-brain barrier permeability using the in situ mouse brain perfu-sion technique. Pharm. Res. 26, 1657-1664. doi: 10.1007/s11095-009-9876-4
-
(2009)
Pharm. Res
, vol.26
, pp. 1657-1664
-
-
Zhao, R.1
Kalvass, J.C.2
Pollack, G.M.3
-
271
-
-
41149097086
-
ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration
-
doi: 10.1038/nn2073
-
Zhong, Z., Deane, R., Ali, Z., Parisi, M., Shapovalov, Y., O'banion, M. K., et al. (2008). ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration. Nat. Neurosci. 11, 420-422. doi: 10.1038/nn2073
-
(2008)
Nat. Neurosci
, vol.11
, pp. 420-422
-
-
Zhon, Z.1
Deane, R.2
Ali, Z.3
Parisi, M.4
Shapovalov, Y.5
O'Banion, M.K.6
-
272
-
-
84862809187
-
Quantitative imaging of energy expenditure in human brain
-
doi: 10.1016/j.neuro image.2012.02.013
-
Zhu, X. H., Qiao, H. Y., Du, F., Xiong, Q., Liu, X., Zhang, X. L., et al. (2012). Quantitative imaging of energy expenditure in human brain. Neuroimage 60, 2107-2117. doi: 10.1016/j.neuro image.2012.02.013
-
(2012)
Neuroimage
, vol.60
, pp. 2107-2117
-
-
Zhu, X.H.1
Qiao, H.Y.2
Du, F.3
Xiong, Q.4
Liu, X.5
Zhang, X.L.6
-
273
-
-
51249105318
-
Extracellular matrix of the central nervous system: From neglect to challenge
-
doi: 10.1007/s00418-008-0485-9
-
Zimmermann, D. R., and Dours-Zimmermann, M. T. (2008). Extracellular matrix of the central nervous system: from neglect to challenge. Histochem. Cell Biol. 130, 635-653. doi: 10.1007/s00418-008-0485-9
-
(2008)
Histochem. Cell Biol
, vol.130
, pp. 635-653
-
-
Zimmermann, D.R.1
Dours-Zimmermann, M.T.2
-
274
-
-
34247343262
-
Microvascular injury and blood-brain barrier leakage in Alzheimer's disease
-
doi: 10.1016/j.neuro biolaging.2006.05.016
-
Zipser, B. D., Johanson, C. E., Gonzalez, L., Berzin, T. M., Tavares, R., Hulette, C. M., et al. (2007). Microvascular injury and blood-brain barrier leakage in Alzheimer's disease. Neurobiol. Aging 28, 977-986. doi: 10.1016/j.neuro biolaging.2006.05.016
-
(2007)
Neurobiol. Aging
, vol.28
, pp. 977-986
-
-
Zipser, B.D.1
Johanson, C.E.2
Gonzalez, L.3
Berzin, T.M.4
Tavares, R.5
Hulette, C.M.6
-
275
-
-
13544268809
-
Neurovascular mechanisms of Alzheimer's neurodegeneration
-
doi: 10.1016/j.tins.2005.02.001
-
Zlokovic, B. V. (2005). Neurovascular mechanisms of Alzheimer's neurodegeneration. Trends Neurosci. 28, 202-208. doi: 10.1016/j.tins.2005.02.001
-
(2005)
Trends Neurosci
, vol.28
, pp. 202-208
-
-
Zlokovic, B.V.1
-
276
-
-
0037223147
-
Neuron-to-astrocyte signaling is central to the dynamic control of brain microcirculation
-
doi: 10.1038/nn980
-
Zonta, M., Angulo, M. C., Gobbo, S., Rosengarten, B., Hossmann, K. A., Pozzan, T., et al. (2003). Neuron-to-astrocyte signaling is central to the dynamic control of brain microcirculation. Nat. Neurosci. 6, 43-50. doi: 10.1038/nn980
-
(2003)
Nat. Neurosci
, vol.6
, pp. 43-50
-
-
Zonta, M.1
Angulo, M.C.2
Gobbo, S.3
Rosengarten, B.4
Hossmann, K.A.5
Pozzan, T.6
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