The blood-central nervous system barriers actively control immune cell entry into the central nervous system

Current Pharmaceutical Design

Volumn 14, Issue 16, 2008, Pages 1555-1565

  Engelhardt, Britta ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

4 integrin; Blood brain barrier; Choroid plexus; Leukocyte trafficking; Natalizumab

Indexed keywords

ALPHA4 INTEGRIN; CD31 ANTIGEN; CLAUDIN; INTERCELLULAR ADHESION MOLECULE 1; JUNCTIONAL ADHESION MOLECULE A; LAMININ; MAJOR HISTOCOMPATIBILITY ANTIGEN; NATALIZUMAB; OCCLUDIN;

ANTIGEN PRESENTING CELL; BASEMENT MEMBRANE; BLOOD BRAIN BARRIER; BLOOD CEREBROSPINAL FLUID BARRIER; BRAIN EDEMA; CELL MEMBRANE TRANSPORT; CENTRAL NERVOUS SYSTEM; CHOROID PLEXUS; CLINICAL TRIAL; CYTOKINE PRODUCTION; DRUG MECHANISM; ENCEPHALOMYELITIS; ENDOTHELIUM CELL; EPITHELIUM CELL; HUMAN; IMMUNOCOMPETENT CELL; LYMPHOCYTE MIGRATION; MEMBRANE DAMAGE; MULTIPLE SCLEROSIS; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; PROTEIN TARGETING; REGULATORY MECHANISM; REVIEW; RISK FACTOR; SIGNAL TRANSDUCTION; TANYCYTE; TIGHT JUNCTION;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGEN PRESENTATION; BLOOD-BRAIN BARRIER; CELL MIGRATION INHIBITION; CELL MOVEMENT; CENTRAL NERVOUS SYSTEM; CEREBROSPINAL FLUID; CHEMOTAXIS, LEUKOCYTE; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; HUMANS; INTEGRIN ALPHA4; MULTIPLE SCLEROSIS; T-LYMPHOCYTES;

EID: 48949117580     PISSN: 13816128     EISSN: None     Source Type: Journal    
DOI: 10.2174/138161208784705432     Document Type: Review

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