SCOPUS 정보 검색 플랫폼

Volumn 9, Issue 3, 2001, Pages 223-228

Affinity for the P-glycoprotein efflux pump at the blood-brain barrier may explain the lack of CNS side-effects of modern antihistamines

(5) Chishty, M a Reichel, A a Siva, J a Abbott, N J a Begley, D J a

a KING'S COLLEGE LONDON (United Kingdom)

Author keywords

Antihistamine; Blood brain barrier; CNS side effects; P glycoprotein; RBE4; Sedation

Indexed keywords

ANTIDEPRESSANT AGENT; ANTIHISTAMINIC AGENT; ASTEMIZOLE; BASIC FIBROBLAST GROWTH FACTOR; CARBON 14; COLCHICINE; DIPHENHYDRAMINE; GLYCOPROTEIN P; HISTAMINE H1 RECEPTOR; HISTAMINE H1 RECEPTOR ANTAGONIST; HYDROXYZINE; IMIPRAMINE; MEPYRAMINE; SEDATIVE AGENT; SUCROSE; TEMELASTINE; TERFENADINE; TRITIUM; VERAPAMIL;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BLOOD BRAIN BARRIER; BRAIN CORTEX; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG TARGETING; DRUG UPTAKE; ENDOTHELIUM CELL; HYPOTHESIS; IN VITRO STUDY; LIPOPHILICITY; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN TRANSPORT; RAT; SEDATION; STRUCTURE ANALYSIS; TOXICITY TESTING;

EID: 0034888307 PISSN: 1061186X EISSN: None Source Type: Journal
DOI: 10.3109/10611860108997930 Document Type: Article

Times cited : (74)

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