-
1
-
-
0030898087
-
Drug equilibration across the blood-brain barrier - Pharmacokinetic considerations based on the microdialysis method
-
M. Hammarlund-Udenaes, L. K. Paalzow, and E. C. de Lange. Drug equilibration across the blood-brain barrier - pharmacokinetic considerations based on the microdialysis method. Pharm. Res. 14:128-134 (1997).
-
(1997)
Pharm. Res.
, vol.14
, pp. 128-134
-
-
Hammarlund-Udenaes, M.1
Paalzow, L.K.2
De Lange, E.C.3
-
2
-
-
0000909084
-
The role of P-glycoprotein in blood-brain barrier transport of morphine: Transcortical microdialysis studies in mdr1a (-/-) and mdr1a (+/+) mice
-
R. Xie, M. Hammarlund-Udenaes, A. G. de Boer, and E. C. de Lange. The role of P-glycoprotein in blood-brain barrier transport of morphine: transcortical microdialysis studies in mdr1a (-/-) and mdr1a (+/+) mice. Br. J. Pharmacol. 128:563-568 (1999).
-
(1999)
Br. J. Pharmacol.
, vol.128
, pp. 563-568
-
-
Xie, R.1
Hammarlund-Udenaes, M.2
De Boer, A.G.3
De Lange, E.C.4
-
3
-
-
0033060742
-
Effects of a potent and specific P-glycoprotein inhibitor on the blood-brain barrier distribution and antinociceptive effect of morphine in the rat
-
S. P. Letrent, G. M. Pollack, K. R. Brouwer, and K. L. Brouwer. Effects of a potent and specific P-glycoprotein inhibitor on the blood-brain barrier distribution and antinociceptive effect of morphine in the rat. Drug Metab. Dispos. 27:827-834 (1999).
-
(1999)
Drug Metab. Dispos.
, vol.27
, pp. 827-834
-
-
Letrent, S.P.1
Pollack, G.M.2
Brouwer, K.R.3
Brouwer, K.L.4
-
4
-
-
0034527760
-
Modelling of the blood-brain barrier transport of morphine-3-glucuronide studied using microdialysis in the rat: Involvement of probenecid-sensitive transport
-
R. Xie, M. R. Bouw, and M. Hammarlund-Udenaes. Modelling of the blood-brain barrier transport of morphine-3-glucuronide studied using microdialysis in the rat: involvement of probenecid-sensitive transport. Br. J. Pharmacol. 131:1784-1792 (2000).
-
(2000)
Br. J. Pharmacol.
, vol.131
, pp. 1784-1792
-
-
Xie, R.1
Bouw, M.R.2
Hammarlund-Udenaes, M.3
-
5
-
-
0020623376
-
Potentiation of morphine analgesia after pretreatment with probenecid or sulfinpyrazone
-
R. A. Morin and W. H. Lyness. Potentiation of morphine analgesia after pretreatment with probenecid or sulfinpyrazone. Pharmacol. Biochem. Behav. 18:885-889 (1983).
-
(1983)
Pharmacol. Biochem. Behav.
, vol.18
, pp. 885-889
-
-
Morin, R.A.1
Lyness, W.H.2
-
6
-
-
0029958849
-
Transport properties of the multidrug resistance-associated protein (MRP) in human tumour cells
-
Z. Hollo, L. Homolya, T. Hegedus, and B. Sarkadi. Transport properties of the multidrug resistance-associated protein (MRP) in human tumour cells. FEBS Lett. 383:99-104 (1996).
-
(1996)
FEBS Lett.
, vol.383
, pp. 99-104
-
-
Hollo, Z.1
Homolya, L.2
Hegedus, T.3
Sarkadi, B.4
-
7
-
-
0031594608
-
99mTc-sestamibi is a substrate for P-glycoprotein and the multidrug resistance-associated protein
-
N. H. Hendrikse, E. J. Franssen, W. T. van der Graaf, C. Meijer, D. A. Piers, W. Vaalburg, and E. G. de Vries. 99mTc-sestamibi is a substrate for P-glycoprotein and the multidrug resistance-associated protein. Br. J. Cancer 77:353-358 (1998).
-
(1998)
Br. J. Cancer
, vol.77
, pp. 353-358
-
-
Hendrikse, N.H.1
Franssen, E.J.2
Van Der Graaf, W.T.3
Meijer, C.4
Piers, D.A.5
Vaalburg, W.6
De Vries, E.G.7
-
8
-
-
0034674901
-
A family of drug transporters: The multidrug resistance-associated proteins
-
P. Borst, R. Evers, M. Kool, and J. Wijnholds. A family of drug transporters: the multidrug resistance-associated proteins. J. Natl. Cancer Inst. 92:1295-1302 (2000).
-
(2000)
J. Natl. Cancer Inst.
, vol.92
, pp. 1295-1302
-
-
Borst, P.1
Evers, R.2
Kool, M.3
Wijnholds, J.4
-
9
-
-
0034623293
-
Expression of various multidrug resistance-associated protein (MRP) homologues in brain microvessel endothelial cells
-
Y. Zhang, H. Han, W. F. Elmquist, and D. W. Miller. Expression of various multidrug resistance-associated protein (MRP) homologues in brain microvessel endothelial cells. Brain Res. 876:148-153 (2000).
-
(2000)
Brain Res.
, vol.876
, pp. 148-153
-
-
Zhang, Y.1
Han, H.2
Elmquist, W.F.3
Miller, D.W.4
-
10
-
-
0034978374
-
Characterization of the efflux transport of 17beta-estradiol-D-17beta-glucuronide from the brain across the blood-brain barrier
-
D. Sugiyama, H. Kusuhara, Y. Shitara, T. Abe, P. J. Meier, T. Sekine, H. Endou, H. Suzuki, and Y. Sugiyama. Characterization of the efflux transport of 17beta-estradiol-D-17beta-glucuronide from the brain across the blood-brain barrier. J. Pharmacol. Exp. Ther. 298:316-322 (2001).
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.298
, pp. 316-322
-
-
Sugiyama, D.1
Kusuhara, H.2
Shitara, Y.3
Abe, T.4
Meier, P.J.5
Sekine, T.6
Endou, H.7
Suzuki, H.8
Sugiyama, Y.9
-
11
-
-
0025758545
-
Species difference of site-selective glucuronidation of morphine
-
C. K. Kuo, N. Hanioka, Y. Hoshikawa, K. Oguri, and H. Yoshimura. Species difference of site-selective glucuronidation of morphine. J. Pharmacobiodyn. 14:187-193 (1991).
-
(1991)
J. Pharmacobiodyn.
, vol.14
, pp. 187-193
-
-
Kuo, C.K.1
Hanioka, N.2
Hoshikawa, Y.3
Oguri, K.4
Yoshimura, H.5
-
12
-
-
0025786748
-
Renal tubular transport of morphine, morphine-6-glucuronide, and morphine-3-glucuronide in the isolated perfused rat kidney
-
J. T. Van Crugten, B. C. Sallustio, R. L. Nation, and A. A. Somogyi. Renal tubular transport of morphine, morphine-6-glucuronide, and morphine-3-glucuronide in the isolated perfused rat kidney. Drug Metab. Dispos. 19:1087-1092 (1991).
-
(1991)
Drug Metab. Dispos.
, vol.19
, pp. 1087-1092
-
-
Van Crugten, J.T.1
Sallustio, B.C.2
Nation, R.L.3
Somogyi, A.A.4
-
13
-
-
0031786058
-
Methodological aspects of the use of a calibrator in in vivo microdialysis-further development of the retrodialysis method
-
M. R. Bouw and M. Hammarlund-Udenaes. Methodological aspects of the use of a calibrator in in vivo microdialysis-further development of the retrodialysis method. Pharm. Res. 15:1673-1679 (1998).
-
(1998)
Pharm. Res.
, vol.15
, pp. 1673-1679
-
-
Bouw, M.R.1
Hammarlund-Udenaes, M.2
-
15
-
-
0027484235
-
Modeling of tolerance development and rebound effect during different intravenous administrations of morphine to rats
-
M. Ekblom, M. Hammarlund-Udenaes, and L. Paalzow. Modeling of tolerance development and rebound effect during different intravenous administrations of morphine to rats. J. Pharmacol. Exp. Ther. 266:244-252 (1993).
-
(1993)
J. Pharmacol. Exp. Ther.
, vol.266
, pp. 244-252
-
-
Ekblom, M.1
Hammarlund-Udenaes, M.2
Paalzow, L.3
-
16
-
-
0023786649
-
An improved method for the simultaneous determination of morphine and its principal glucuronide metabolites
-
S. P. Joel, R. J. Osborne, and M. L. Slevin. An improved method for the simultaneous determination of morphine and its principal glucuronide metabolites. J. Chromatogr. 430:394-399 1988).
-
(1988)
J. Chromatogr.
, vol.430
, pp. 394-399
-
-
Joel, S.P.1
Osborne, R.J.2
Slevin, M.L.3
-
17
-
-
0003747347
-
-
NONMEM Project Group, University of California at San Fransisco, San Fransisco, California
-
S. L. Beal and L. S. Sheiner. NONMEM User's Guide. NONMEM Project Group, University of California at San Fransisco, San Fransisco, California, 1992.
-
(1992)
NONMEM User's Guide
-
-
Beal, S.L.1
Sheiner, L.S.2
-
18
-
-
0002322365
-
Xpose - An S-PLUS based population pharmacokinetic/pharmacodynamic model building aid for NONMEM
-
E. N. Jonsson and M. O. Karlsson. Xpose - an S-PLUS based population pharmacokinetic/pharmacodynamic model building aid for NONMEM. Comput. Methods Programs Biomed. 58:51-64 (1999).
-
(1999)
Comput. Methods Programs Biomed.
, vol.58
, pp. 51-64
-
-
Jonsson, E.N.1
Karlsson, M.O.2
-
19
-
-
0029876793
-
The simultaneous estimation of the influx and efflux blood-brain barrier permeabilities of gabapentin using a microdialysis-pharmacokinetic approach
-
Y. Wang and D. F. Welty. The simultaneous estimation of the influx and efflux blood-brain barrier permeabilities of gabapentin using a microdialysis-pharmacokinetic approach. Pharm. Res. 13:398-403 (1996).
-
(1996)
Pharm. Res.
, vol.13
, pp. 398-403
-
-
Wang, Y.1
Welty, D.F.2
-
20
-
-
0031830331
-
A preliminary study on the distribution of morphine and its glucuronides in the subcompartments of blood
-
G. Skopp, L. Potsch, B. Ganssmann, R. Aderjan, and R. Mattern. A preliminary study on the distribution of morphine and its glucuronides in the subcompartments of blood. J. Anal. Toxicol. 22:261-264 (1998).
-
(1998)
J. Anal. Toxicol.
, vol.22
, pp. 261-264
-
-
Skopp, G.1
Potsch, L.2
Ganssmann, B.3
Aderjan, R.4
Mattern, R.5
-
21
-
-
0030425327
-
Poor permeability of morphine 3-glucuronide and morphine 6-glucuronide through the blood-brain barrier in the rat
-
U. Bickel, O. P. Schumacher, Y. S. Kang, and K. Voigt. Poor permeability of morphine 3-glucuronide and morphine 6-glucuronide through the blood-brain barrier in the rat. J. Pharmacol. Exp. Ther. 278:107-113 (1996).
-
(1996)
J. Pharmacol. Exp. Ther.
, vol.278
, pp. 107-113
-
-
Bickel, U.1
Schumacher, O.P.2
Kang, Y.S.3
Voigt, K.4
-
22
-
-
0034964222
-
Pharmacokinetic and pharmacodynamic implications of P-glycoprotein modulation
-
C. J. Matheny, M. W. Lamb, K. R. Brouwer, and G. M. Pollack. Pharmacokinetic and pharmacodynamic implications of P-glycoprotein modulation. Pharmacotherapy 21:778-796 (2001).
-
(2001)
Pharmacotherapy
, vol.21
, pp. 778-796
-
-
Matheny, C.J.1
Lamb, M.W.2
Brouwer, K.R.3
Pollack, G.M.4
-
23
-
-
0034293553
-
Pharmacokinetic-pharmacodynamic modelling of morphine transport across the blood-brain barrier as a cause of the antinociceptive effect delay in rats - A microdialysis study
-
M. R. Bouw, M. Gardmark, and M. Hammarlund-Udenaes. Pharmacokinetic-pharmacodynamic modelling of morphine transport across the blood-brain barrier as a cause of the antinociceptive effect delay in rats - a microdialysis study. Pharm. Res. 17:1220-1227 (2000).
-
(2000)
Pharm. Res.
, vol.17
, pp. 1220-1227
-
-
Bouw, M.R.1
Gardmark, M.2
Hammarlund-Udenaes, M.3
-
25
-
-
0018903891
-
Bulk flow of brain interstitial fluid under normal and hyperosmolar conditions
-
G. A. Rosenberg, W. T. Kyner, and E. Estrada. Bulk flow of brain interstitial fluid under normal and hyperosmolar conditions. Am. J. Physiol. 238:F42-F49 (1980).
-
(1980)
Am. J. Physiol.
, vol.238
-
-
Rosenberg, G.A.1
Kyner, W.T.2
Estrada, E.3
-
27
-
-
0022414781
-
Effect of probenecid on the formation and elimination of acyl glucuronides: Studies with zomepirac
-
P. C. Smith, P. N. Langendijk, J. A. Bosso, and L. Z. Benet. Effect of probenecid on the formation and elimination of acyl glucuronides: studies with zomepirac. Clin. Pharmacol. Ther. 38:121-127 (1985).
-
(1985)
Clin. Pharmacol. Ther.
, vol.38
, pp. 121-127
-
-
Smith, P.C.1
Langendijk, P.N.2
Bosso, J.A.3
Benet, L.Z.4
-
28
-
-
0027976519
-
Localization of drug-metabolizing enzyme activities to blood-brain interfaces and circumventricular organs
-
J. F. Ghersi-Egea, B. Leninger-Muller, G. Suleman, G. Siest, and A. Minn. Localization of drug-metabolizing enzyme activities to blood-brain interfaces and circumventricular organs. J. Neurochem. 62:1089-1096 (1994).
-
(1994)
J. Neurochem.
, vol.62
, pp. 1089-1096
-
-
Ghersi-Egea, J.F.1
Leninger-Muller, B.2
Suleman, G.3
Siest, G.4
Minn, A.5
-
29
-
-
0025051997
-
Steady-state theory for quantitative microdialysis of solutes and water in vivo and in vitro
-
P. M. Bungay, P. F. Morrison, and R. L. Dedrick. Steady-state theory for quantitative microdialysis of solutes and water in vivo and in vitro. Life Sci. 46:105-119 (1990).
-
(1990)
Life Sci.
, vol.46
, pp. 105-119
-
-
Bungay, P.M.1
Morrison, P.F.2
Dedrick, R.L.3
-
30
-
-
0034998423
-
Effect of capillary efflux transport inhibition on the determination of probe recovery during in vivo microdialysis in the brain
-
H. Sun, P. M. Bungay, and W. F. Elmquist. Effect of capillary efflux transport inhibition on the determination of probe recovery during in vivo microdialysis in the brain. J. Pharmacol. Exp. Ther. 297:991-1000 (2001).
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.297
, pp. 991-1000
-
-
Sun, H.1
Bungay, P.M.2
Elmquist, W.F.3
|