Endothelial claudin: Claudin-5/TMVCF constitutes tight junction strands in endothelial cells

Journal of Cell Biology

Volumn 147, Issue 1, 1999, Pages 185-194

  Morita, Kazumasa ^a   Sasaki, Hiroyuki ^b,c   Furuse, Mikio ^a   Tsukita, Shoichiro ^a  

^a KYOTO UNIVERSITY   (Japan)

^b 600 8815   (Japan)

^c JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Blood vessels; Claudin; Endothelium; Occludin; Tight junction

Indexed keywords

CLAUDIN; MEMBRANE PROTEIN; OCCLUDIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BLOOD VESSEL PERMEABILITY; BRAIN; CELL INTERACTION; CONTROLLED STUDY; ENDOTHELIUM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; TIGHT JUNCTION;

AGING; AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES; BRAIN; BRAIN CHEMISTRY; EMBRYO; ENDOTHELIUM, VASCULAR; INTESTINES; KIDNEY; L CELLS (CELL LINE); LUNG; MEMBRANE PROTEINS; MICE; MOLECULAR SEQUENCE DATA; ORGAN SPECIFICITY; RABBITS; RECOMBINANT FUSION PROTEINS; TIGHT JUNCTIONS; TRANSFECTION;

ANIMALIA;

EID: 0033523758     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.147.1.185     Document Type: Article

References (56)

1. Anderson, J.M., and CM. Van Itallie. 1995. Tight junctions and the molecular basis for regulation of paracellular permeability. Am. J. Physiol. 269:G467-G475.
2. Ando-Akatsuka, Y., M. Saitou, T. Hirase, M. Kishi, A. Sakakibara, M. Itoh, S. Yonemura, M. Furuse, and Sh. Tsukita. 1996. Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues. J. Cell Biol. 133:43-47.
3. Balda, M.S., L. González-Mariscal, K. Matter, M. Cereijido, and J.M. Anderson. 1993. Assembly of the tight junction: the role of diacylglycerol. J. Cell Biol. 123:293-302.
4. Balda, M.S., J.A. Whitney, C. Flores, S. González, M. Cereijido, and K. Matter. 1996. Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane protein. J. Cell Biol. 134:1031-1049.
5. Bowman, P.D., M. du Bois, R.R. Shivers, and K. Dorovini-Zis. 1992. Endothelial tight junctions. In Tight Junctions. M. Cereijido, editor. CRC Press, London. 305-320.
6. Brightman, M.W., and T.S. Reese. 1969. Junctions between intimately apposed cell membranes in the vertebrate brain. J. Cell Biol. 40:648-677.
7. Chen, Y.-H., C. Merzdorf, D.L. Paul, and D.A. Goodenough. 1997. COOH terminus of occludin is required for tight junction barrier function in early Xenopus embryos. J. Cell Biol. 138:891-899.
8. Chen, Z., M. Zandonatti, D. Jakubowski, and H.S. Fox. 1998. Brain capillary endothelial cells express MBEC1, a protein that is related to the Clostridium perfringens enterotoxin receptors. Lab. Invest. 78:353-363.
9. Citi, S., H. Sabanay, R. Jakes, B. Geiger, and J. Kendrick-Jones. 1988. Cingulin, a new peripheral component of tight junctions. Nature. 333:272-276.
10. Dempsey, G.P., and S. Bullivant. 1973. Endothelial cell membranes: polarity of particles as seen by freeze-fracturing. Science. 179:190-192.
11. Farquhar, M.G., and G.E. Palade. 1963. Junctional complexes in various epithelia. J. Cell Biol. 17:375-412.
12. Farrell, C.L., and W. Risau. 1994. Normal and abnormal development of the blood-brain barrier. Microsc. Res. Tech. 27:495-506.
13. Fujimoto, K. 1995. Freeze-fracture replica electron microscopy combined with SDS digestion for cytochemical labeling of integral membrane proteins. Application to the immunogold labeling of intercellular Junctional complexes. J. Cell Sci. 108:3443-3449.
14. Furuse, M., T. Hirase, M. Itoh, A. Nagafuchi, S. Yonemura, Sa. Tsukita, and Sh. Tsukita. 1993. Occludin: a novel integral membrane protein localizing at tight junctions. J. Cell Biol. 123:1777-1788.
15. Furuse, M., K. Fujimoto, N. Sato, T. Hirase, Sa. Tsukita, and Sh. Tsukita. 1996. Overexpression of occludin, a tight junction-associated integral membrane protein, induces the formation of intracellular multilamellar bodies bearing tight junction-like structures. J. Cell Sci. 109:429-435.
16. Furuse, M., K. Fujita, T. Hiiragi, K. Fujimoto, and Sh. Tsukita. 1998a. Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin. J. Cell Biol. 141:1539-1550.
17. Furuse, M., H. Sasaki, K. Fujimoto, and Sh. Tsukita. 1998b. A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblasts. J. Cell Biol. 143:391-401.
18. Gale, N.W., and G.D. Yancopoulos. 1999. Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and ephrins in vascular development. Genes Dev. 13:1055-1066.
19. Goodenough, D.A. 1999. Plugging the leaks. Proc. Natl. Acad. Sci. USA. 96: 319-321.
20. Gumbiner, B. 1987. Structure, biochemistry, and assembly of epithelial tight junctions. Am. J. Physiol. 253:C749-C758.
21. Gumbiner, B. 1993. Breaking through the tight junction barrier. J. Cell Biol. 123:1631-1633.
22. Gumbiner, B., T. Lowenkopf, and D. Apatira. 1991. Identification of a 160-kDa polypeptide that binds to the tight junction protein ZO-1. Proc. Natl. Acad. Sci. USA. 88:3460-3464.
23. Haskins, J., L. Gu, E.S. Wittchen, J. Hibbard, and B.R. Stevenson. 1998. ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludin. J. Cell Biol. 141:199-208.
24. Hirase, T., J.M. Staddon, M. Saitou, Y. Ando-Akatsuka, M. Itoh, M. Furuse, K. Fujimoto, Sh. Tsukita, and L.L. Rubin. 1997. Occludin as a possible determinant of tight junction permeability in endothelial cells. J. Cell Sci. 110:1603-1613.
25. Keon, B.H., S. Schäfer, C. Kuhn, C. Grund, and W.W. Franke. 1996. Symplekin, a novel type of tight junction plaque protein. J. Cell Biol. 134:1003-1018.
26. Kevil, C.G., D.K. Payne, E. Mire, and J.S. Alexander. 1998. Vascular permeability factor/vascular endothelial cell growth factor-mediated permeability occurs through disorganization of endothelial junctional proteins. J. Biol. Chem. 273:15099-15103.
27. Kniesel, U., W. Risau, and H. Wolburg. 1996. Development of blood-brain barrier tight junctions in the rat cortex. Dev. Brain Res. 96:229-240.
28. Laemmli, U.K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:680-685.
29. Lampugnani, M.G., M. Corada, L. Caveda, F. Breviario, O. Ayalon, B. Geiger, and E. Dejana. 1995 The molecular organization of endothelial cell to cell junctions: differential association of plakoglobin, β-catenin, and α-catenin with vascular endothelial cadherin (VE-cadherin). J. Cell Biol. 129: 203-217.
30. McCarthy, K.M., I.E. Skare, M.C. Stankewich, M. Furuse, Sh. Tsukita, R.A. Rogers, R.D. Lynch, and E.E. Schneeberger. 1996. Occludin is a functional component of the tight junction. J. Cell Sci. 109:2287-2298.
31. Møllgård, K., and N.R. Saunders. 1975. Complex tight junctions of epithelial and endotheliat cells in early foetal brain. J. Neurocytol. 4:453-468.
32. Morita, K., M. Furuse, K. Fujimoto, and Sh. Tsukita. 1999a. Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands. Proc. Natl. Acad. Sci. USA. 96:511-516.
33. Morita, K., H. Sasaki, K. Fujimoto, M. Furuse, and Sh. Tsukita. 1999b. Claudin-11/OSP-based light junctions in myelinated sheaths of oligodendrocytes and Sertoli cells in testis. J. Cell Biol. 145:579-588.
34. Niwa, H., K. Yamamura, and J. Miyazaki. 1991. Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene. 108:193-200.
35. Reese, T.J., and M.J. Karnovsky. 1967. Fine structural localization of a blood-brain barrier to exogenous peroxidase. J. Cell Biol. 34:207-217.
36. Risau, W., and H. Wolburg. 1990. Development of the blood-brain barrier. Trends Neurosci. 13:174-178.
37. Risau, W., and I. Flamme. 1995. Vasculogenesis. Annu. Rev. Cell Dev. Biol. 11: 73-91.
38. Risau, W., S. Esser, and B. Engelhardt. 1998. Differentiation of blood-brain barrier endothelial cells. Pathol. Biol. 46:171-175.
39. Rubin, L.L. 1992. Endothelial cells: adhesion and tight junctions. Curr. Opin. Cell Biol. 4:830-833.
40. Saitou, M., Y. Ando-Akatsuka, M. Itoh, M. Furuse, J. Inazawa, K. Fujimoto, and Sh. Tsukita. 1997. Mammalian occludin in epithelial cells: its expression and subcellular distribution. Eur. J. Cell Biol. 73:222-231.
41. Saitou, M., K. Fujimoto, Y. Doi, M. Itoh, T. Fujimoto, M. Furuse, H. Takano, T. Noda, and Sh. Tsukita. 1998. Occludin-deficient embryonic stem cells can differentiate into polarized epithelial cells bearing tight junctions. J. Cell Biol. 141:397-408.
42. Schneeberger, E.E. 1982. Structure of intercellular junctions in different segments of the intrapulmonary vasculature. Ann. NY Acad. Sci. 384:54-63.
43. Schneeberger, E.E., and R.D. Lynch. 1992. Structure, function, and regulation of cellular tight junctions. Am. J. Physiol. 262:L647-L661.
44. Simionescu, M., N. Simionescu, and G.E. Palade. 1975. Segmental differentiation of cell junctions in the vascular endothelium. The microvasculature. J. Cell Biol. 67:863-885.
45. Simionescu, M., N. Simionescu, and G.E. Palade. 1976. Segmental differentiation of cell junctions in the vascular endothelium. Arteries and veins. J. Cell Biol. 68:705-723.
46. Sirotkin, H., B. Morrow, B. Saint-Jore, A. Puech, R. Das Gupta, S.R. Patanjali, A. Skoultchi, S.M. Weissman, R. Kucherlapali. 1997. Identification, characterization, and precise mapping of a human gene encoding a novel membrane-spanning protein from the 22q11 region deleted in velo-cardio-facial syndrome. Genomics. 42:245-251.
47. Spring, K. 1998. Routes and mechanism of fluid transport by epithelia. Annu. Rev. Physiol. 60:105-119.
48. Staehelin, L.A. 1973. Further observations on the fine structure of freeze-cleaved tight junctions. J. Cell Sci. 13:763-786.
49. Staehelin, L.A. 1974. Structure and function of intercellular junctions. Int. Rev. Cytol. 39:191-283.
50. Stevenson, B.R., J.D. Siliciano, M.S. Mooseker, and D.A. Goodenough. 1986. Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia. J. Cell Biol. 103:755-766.
51. Tsukita, Sh., and M. Furuse. 1999. Occludin and claudins in tight junction strands: leading or supporting players? Trends Cell Biol. 9:268-273.
52. Van Itallie, C.M., and J.M. Anderson. 1997. Occludin confers adhesiveness when expressed in fibroblasts. J. Cell Sci. 110:1113-1121.
53. Wolburg, H., J. Neuhaus, U. Kniesel, B. Krauss, E.M. Schmid, M. Öcalan, C. Farrell, and W. Risau. 1994. Modulation of tight junction structure in blood-brain barrier endothelial cells. Effects of tissue culture, second messengers and cocultured astrocytes. J. Cell Sci. 107:1347-1357.
54. Wong, V., and B.M. Gumbiner. 1997. A synthetic peptide corresponding to the extracellular domain of occludin perturbs the tight junction permeability barrier. J. Cell Biol. 136:399-409.
55. Yap, A.S., J.M. Mullin, and B.R. Stevenson. 1998. Molecular analysis of tight junction physiology: insights and paradoxes. J. Membr. Biol. 163:159-167.
56. Zhong, Y., T. Saitoh, T. Minase, N. Sawada, K. Enomoto, and M. Mori. 1993. Monoclonal antibody 7H6 reacts with a novel tight junction-associated protein distinct from ZO-1, cingulin, and ZO-2. J. Cell Biol. 120:477-483.