Regulation of insulin receptor substrate-1 by mTORC2 (mammalian target of rapamycin complex 2)

Biochemical Society Transactions

Volumn 41, Issue 4, 2013, Pages 896-901

  DeStefano, Michael A ^a   Jacinto, Estela ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

Insulin receptor substrate (IRS) 1 degradation; Insulin resistance; Mammalian target of rapamycin complex 2 (mTORC2); Rapamycin; Rapamycin insensitive companion of mammalian target of rapamycin (rictor)

Indexed keywords

CULLIN; CULLIN 7; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; PROTEIN; PROTEIN FBW8; SERINE; UNCLASSIFIED DRUG;

ARTICLE; CYTOSOL; DOWN REGULATION; ENZYME SUBSTRATE; HUMAN; INSULIN RESISTANCE; LONG TERM EXPOSURE; NEGATIVE FEEDBACK; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; UBIQUITINATION;

ANIMALS; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; MICE; MULTIPROTEIN COMPLEXES; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84880529782     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST20130018     Document Type: Article

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