Pathophysiology of vascular calcification: Pivotal role of cellular senescence in vascular smooth muscle cells

Experimental Gerontology

Volumn 45, Issue 11, 2010, Pages 819-824

  Burton, D G A ^a   Matsubara, H ^b   Ikeda, K ^b  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b KYOTO PREFECTURAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Ageing; Cellular senescence; CESP; RUNX 2; SASP; Vascular calcification; Vascular smooth muscle

Indexed keywords

BONE MORPHOGENETIC PROTEIN; CYTOKINE; GROWTH FACTOR; INTERLEUKIN 6; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR RUNX2; WNT PROTEIN;

BLOOD VESSEL CALCIFICATION; CELL ACTIVITY; CELL AGING; CELL DIFFERENTIATION; CELL TRANSFORMATION; GENETIC TRANSCRIPTION; HUMAN; MOLECULAR MECHANICS; NONHUMAN; OSTEOBLAST; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW; RISK FACTOR; SENESCENCE; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ALKALINE PHOSPHATASE; ANIMALS; BONE MORPHOGENETIC PROTEIN 2; CALCINOSIS; CELL AGING; COLLAGEN TYPE I; CORE BINDING FACTOR ALPHA 1 SUBUNIT; GENE EXPRESSION; HUMANS; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PHENOTYPE; UP-REGULATION; VASCULAR DISEASES;

EID: 77957794662     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exger.2010.07.005     Document Type: Review

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