-
4
-
-
43949137133
-
Nanotechnology improving. Targeted delivery
-
M.M. Amiji Nanotechnology improving. Targeted delivery Drug Delivery 17 2007 53 56
-
(2007)
Drug Delivery
, vol.17
, pp. 53-56
-
-
Amiji, M.M.1
-
6
-
-
81855170441
-
Nanomedicine(s) under the microscope
-
R. Duncan, and R. Gaspar Nanomedicine(s) under the microscope Molecular Pharmaceutics 8 2011 2101 2141
-
(2011)
Molecular Pharmaceutics
, vol.8
, pp. 2101-2141
-
-
Duncan, R.1
Gaspar, R.2
-
7
-
-
77953374462
-
Recent advances in the field of nanometric drug carriers
-
J. Ogier, T. Arnauld, and E. Doris Recent advances in the field of nanometric drug carriers Future Medicinal Chemistry 1 2009 693 711
-
(2009)
Future Medicinal Chemistry
, vol.1
, pp. 693-711
-
-
Ogier, J.1
Arnauld, T.2
Doris, E.3
-
9
-
-
14644439267
-
Cancer nanotechnology: Opportunities and challenges
-
M. Ferrari Cancer nanotechnology: opportunities and challenges Nature Reviews Cancer 5 2005 161 171
-
(2005)
Nature Reviews Cancer
, vol.5
, pp. 161-171
-
-
Ferrari, M.1
-
10
-
-
80053929670
-
Personalizing nanomedicine
-
L.K. Wolf Personalizing nanomedicine Chemical and Engineering News 89 39 2011 29 32
-
(2011)
Chemical and Engineering News
, vol.89
, Issue.39
, pp. 29-32
-
-
Wolf, L.K.1
-
11
-
-
84865513273
-
Theranostic applications of nanoparticles in cancer
-
N. Ahmed, H. Fessi, and A. Elaissari Theranostic applications of nanoparticles in cancer Drug Discovery Today 17 2012 928 934
-
(2012)
Drug Discovery Today
, vol.17
, pp. 928-934
-
-
Ahmed, N.1
Fessi, H.2
Elaissari, A.3
-
12
-
-
84870380689
-
Multi-dye theranostic nanoparticle platform for bioimaging and cancer therapy
-
A.K. Singh, M.A. Hahn, L.G. Gutwein, M.C. Rule, J.A. Knapik, B.M. Moudgil, S.R. Grobmyer, and S.C. Brown Multi-dye theranostic nanoparticle platform for bioimaging and cancer therapy International Journal of Nanomedicine 7 2012 2739 2750
-
(2012)
International Journal of Nanomedicine
, vol.7
, pp. 2739-2750
-
-
Singh, A.K.1
Hahn, M.A.2
Gutwein, L.G.3
Rule, M.C.4
Knapik, J.A.5
Moudgil, B.M.6
Grobmyer, S.R.7
Brown, S.C.8
-
16
-
-
84859965276
-
Dendrimer: A novel polymer for drug delivery
-
P. Kumar, K.P. Meena, P. Kumar, C. Choudhary, D.S. Thakur, and P. Bajpayee Dendrimer: a novel polymer for drug delivery Journal of Innovative Trends in Pharmaceutical Sciences 1 2010 252 269
-
(2010)
Journal of Innovative Trends in Pharmaceutical Sciences
, vol.1
, pp. 252-269
-
-
Kumar, P.1
Meena, K.P.2
Kumar, P.3
Choudhary, C.4
Thakur, D.S.5
Bajpayee, P.6
-
17
-
-
84878946032
-
Dendrimers: Polymers of 21st century
-
Online only: (accessed February 2013).
-
H.V. Chavda Dendrimers: polymers of 21st century Pharmacological Reviews 5 2007 E.65 Online only: http://www.pharmainfo.net/reviews/dendrimers-polymers- 21-st-century (accessed February 2013).
-
(2007)
Pharmacological Reviews
, vol.5
, pp. 65
-
-
Chavda, H.V.1
-
18
-
-
84989581991
-
"cascade"-and "nonskid-Chain-like" syntheses of molecular cavity topologies
-
E. Buhleier, W. Wehner, and F. Vögtle "Cascade"-and "Nonskid-Chain-like" syntheses of molecular cavity topologies Synthesis 2 1978 155 158
-
(1978)
Synthesis
, vol.2
, pp. 155-158
-
-
Buhleier, E.1
Wehner, W.2
Vögtle, F.3
-
20
-
-
78650316044
-
Biomedical applications of dendrimers: A tutorial
-
M.A. Mintzer, and M.W. Grinstaff Biomedical applications of dendrimers: a tutorial Chemical Society Reviews 40 2010 173 190
-
(2010)
Chemical Society Reviews
, vol.40
, pp. 173-190
-
-
Mintzer, M.A.1
Grinstaff, M.W.2
-
21
-
-
77951234285
-
Dendrimers designed for functions: From physical photophysical and supramolecular properties to applications in sensing catalysis molecular electronics photonics and nanomedicine
-
D. Astruc, E. Boisselier, and C. Omelas Dendrimers designed for functions: from physical photophysical and supramolecular properties to applications in sensing catalysis molecular electronics photonics and nanomedicine Chemical Reviews 110 2010 1857 1959
-
(2010)
Chemical Reviews
, vol.110
, pp. 1857-1959
-
-
Astruc, D.1
Boisselier, E.2
Omelas, C.3
-
22
-
-
77949275122
-
Dendrimer-based drug and imaging conjugates: Design considerations for nanomedical applications
-
A.R. Menjoge, R.M. Kannan, and D.A. Tomalia Dendrimer-based drug and imaging conjugates: design considerations for nanomedical applications Drug Discovery Today 15 2010 171 185
-
(2010)
Drug Discovery Today
, vol.15
, pp. 171-185
-
-
Menjoge, A.R.1
Kannan, R.M.2
Tomalia, D.A.3
-
25
-
-
12844258906
-
Dendrimers and dendritic polymers in drug delivery
-
E.R. Gillies, and J.M. Fréchet Dendrimers and dendritic polymers in drug delivery Drug Discovery Today 10 2005 35 42
-
(2005)
Drug Discovery Today
, vol.10
, pp. 35-42
-
-
Gillies, E.R.1
Fréchet, J.M.2
-
26
-
-
70349129495
-
Dendrimers: Emerging polymers for drug-delivery systems
-
B.K. Nanjwade, H.M. Bechra, G.K. Derkar, F.V. Manvi, and V.K. Nanjwade Dendrimers: emerging polymers for drug-delivery systems European Journal of Pharmaceutical Sciences 38 2009 185 196
-
(2009)
European Journal of Pharmaceutical Sciences
, vol.38
, pp. 185-196
-
-
Nanjwade, B.K.1
Bechra, H.M.2
Derkar, G.K.3
Manvi, F.V.4
Nanjwade, V.K.5
-
27
-
-
43449117468
-
Therapeutic and diagnostic applications of dendrimers for cancer treatment
-
J.B. Wolinsky, W. Mark, and M. Grinstaff Therapeutic and diagnostic applications of dendrimers for cancer treatment Advanced Drug Delivery Reviews 60 2008 1037 1055
-
(2008)
Advanced Drug Delivery Reviews
, vol.60
, pp. 1037-1055
-
-
Wolinsky, J.B.1
Mark, W.2
Grinstaff, M.3
-
28
-
-
33846503980
-
Design of functional dendritic polymers for application as drug and gene delivery systems
-
Z. Sideratou, L.A. Tziveleka, C. Kontoyianni, D. Tsiourvas, and C.M. Paleo Design of functional dendritic polymers for application as drug and gene delivery systems Gene Therapy & Molecular Biology 10 2006 71 94
-
(2006)
Gene Therapy & Molecular Biology
, vol.10
, pp. 71-94
-
-
Sideratou, Z.1
Tziveleka, L.A.2
Kontoyianni, C.3
Tsiourvas, D.4
Paleo, C.M.5
-
29
-
-
84858679264
-
Multifunctional dendritic polymers in nanomedicine: Opportunities and challenges
-
J. Khandare, M. Calderon, N.M. Dagia, and R. Haag Multifunctional dendritic polymers in nanomedicine: opportunities and challenges Chemical Society Reviews 41 2012 2824 2848
-
(2012)
Chemical Society Reviews
, vol.41
, pp. 2824-2848
-
-
Khandare, J.1
Calderon, M.2
Dagia, N.M.3
Haag, R.4
-
30
-
-
84862755672
-
Polyether based amphiphiles for delivery of active compounds
-
S. Gupta, R. Tyagi, V.S. Parmar, S.K. Sharma, and R. Haag Polyether based amphiphiles for delivery of active compounds Polymer 53 2012 3053 3078
-
(2012)
Polymer
, vol.53
, pp. 3053-3078
-
-
Gupta, S.1
Tyagi, R.2
Parmar, V.S.3
Sharma, S.K.4
Haag, R.5
-
31
-
-
77952937434
-
Host-guest of dendrimer-drug complexes. An in-depth look into the binding/encapsulation of guanosine monophosphate by dendrimers
-
J. Hu, M. Fang, Y. Cheng, J. Zhang, Q. Wu, and T. Xu Host-guest of dendrimer-drug complexes. An in-depth look into the binding/encapsulation of guanosine monophosphate by dendrimers Journal of Physical Chemistry 114 2010 7148 7157
-
(2010)
Journal of Physical Chemistry
, vol.114
, pp. 7148-7157
-
-
Hu, J.1
Fang, M.2
Cheng, Y.3
Zhang, J.4
Wu, Q.5
Xu, T.6
-
32
-
-
44749084015
-
Potential oral delivery of 7-ethyl-10-hydroxy-camptothecin (SN-38) using poly(amidoamine) dendrimers
-
R.B. Kolhatkar, P. Swaan, and H. Ghandehari Potential oral delivery of 7-ethyl-10-hydroxy-camptothecin (SN-38) using poly(amidoamine) dendrimers Pharmaceutical Research 25 2008 1723 1729
-
(2008)
Pharmaceutical Research
, vol.25
, pp. 1723-1729
-
-
Kolhatkar, R.B.1
Swaan, P.2
Ghandehari, H.3
-
33
-
-
67650690627
-
Dendrimers as carriers for delivery of chemotherapeutic agents
-
S.H. Medina, and M.E.H. El-Sayed Dendrimers as carriers for delivery of chemotherapeutic agents Chemical Reviews 109 2009 3141 3157
-
(2009)
Chemical Reviews
, vol.109
, pp. 3141-3157
-
-
Medina, S.H.1
El-Sayed, M.E.H.2
-
36
-
-
61849153021
-
Impact of nanotechnology on drug delivery
-
O.C. Farokhzad, and R. Langer Impact of nanotechnology on drug delivery ACS Nano 3 2009 16 20
-
(2009)
ACS Nano
, vol.3
, pp. 16-20
-
-
Farokhzad, O.C.1
Langer, R.2
-
38
-
-
51049083983
-
Application of dendrimer-drug complexation in the enhancement of drug solubility and bioavailability
-
N.K. Jain, and U. Gupta Application of dendrimer-drug complexation in the enhancement of drug solubility and bioavailability Expert Opinion on Drug Metabolism and Toxicology 4 2008 1035 1051
-
(2008)
Expert Opinion on Drug Metabolism and Toxicology
, vol.4
, pp. 1035-1051
-
-
Jain, N.K.1
Gupta, U.2
-
39
-
-
77949484232
-
Dendrimer-based nanoparticles for cancer therapy
-
J.R. Baker Dendrimer-based nanoparticles for cancer therapy Nanotechnology for Hematology 1 2009 708 719
-
(2009)
Nanotechnology for Hematology
, vol.1
, pp. 708-719
-
-
Baker, J.R.1
-
40
-
-
84858064291
-
Association of chemotherapeutic drugs with dendrimer nanocarriers: An assessment of the merits of covalent conjugation compared to noncovalent encapsulation
-
L.M. Kaminskas, V.M. McLeod, C.J.H. Porter, and B.J. Boyd Association of chemotherapeutic drugs with dendrimer nanocarriers: an assessment of the merits of covalent conjugation compared to noncovalent encapsulation Molecular Pharmaceutics 9 2012 355 373
-
(2012)
Molecular Pharmaceutics
, vol.9
, pp. 355-373
-
-
Kaminskas, L.M.1
McLeod, V.M.2
Porter, C.J.H.3
Boyd, B.J.4
-
41
-
-
77956517698
-
Self immolative dendrimers: A distinctive approach to molecular amplification
-
M. Avital-Shmilovici, and D. Shabat Self immolative dendrimers: a distinctive approach to molecular amplification Soft Matter 6 2010 1073 1080
-
(2010)
Soft Matter
, vol.6
, pp. 1073-1080
-
-
Avital-Shmilovici, M.1
Shabat, D.2
-
42
-
-
84861233382
-
Stimuli-responsive polymeric nanocarriers for the controlled transport of active compounds: Concepts and applications
-
E. Fleige, M.A. Quadir, and R. Haag Stimuli-responsive polymeric nanocarriers for the controlled transport of active compounds: concepts and applications Advanced Drug Delivery Reviews 64 2012 866 884
-
(2012)
Advanced Drug Delivery Reviews
, vol.64
, pp. 866-884
-
-
Fleige, E.1
Quadir, M.A.2
Haag, R.3
-
44
-
-
59649089796
-
Surface-engineered dendrimers: A solution for toxicity issues
-
V. Mishra, U. Gupta, and N.K. Jain Surface-engineered dendrimers: a solution for toxicity issues Journal of Biomaterials Science 20 2009 141 166
-
(2009)
Journal of Biomaterials Science
, vol.20
, pp. 141-166
-
-
Mishra, V.1
Gupta, U.2
Jain, N.K.3
-
46
-
-
77953680751
-
Understanding specific and nonspecific toxicities: A requirement for the development of dendrimer-based pharmaceuticals
-
D.Q. McNermy, P.R. Leroueil, and J.R. Baker Understanding specific and nonspecific toxicities: a requirement for the development of dendrimer-based pharmaceuticals Nanomedicine and Nanobiotechnology 2 2010 249 259
-
(2010)
Nanomedicine and Nanobiotechnology
, vol.2
, pp. 249-259
-
-
McNermy, D.Q.1
Leroueil, P.R.2
Baker, J.R.3
-
47
-
-
79959874185
-
Designing dendrimers for drug delivery and imaging: Pharmacokinetic considerations
-
W. Wijagkanalan, S. Kawakami, and M. Hashida Designing dendrimers for drug delivery and imaging: pharmacokinetic considerations Pharmaceutical Research 28 2011 1500 1519
-
(2011)
Pharmaceutical Research
, vol.28
, pp. 1500-1519
-
-
Wijagkanalan, W.1
Kawakami, S.2
Hashida, M.3
-
49
-
-
0037345827
-
Macromolecular MRI contrast agents with small dendrimers: Pharmacokinetic differences between sizes and cores
-
H. Kobayashi, S. Kawamoto, S.K. Jo, H.L. Bryant, and M.W. Brechbiel Macromolecular MRI contrast agents with small dendrimers: pharmacokinetic differences between sizes and cores Bioconjugate Chemistry 14 2003 388 394
-
(2003)
Bioconjugate Chemistry
, vol.14
, pp. 388-394
-
-
Kobayashi, H.1
Kawamoto, S.2
Jo, S.K.3
Bryant, H.L.4
Brechbiel, M.W.5
-
50
-
-
4043103282
-
Cytotoxicity hemolysis and acute in vivo toxicity of dendrimers based on melamine candidate vehicles for drug delivery
-
H.T. Chen, M.F. Neerman, A.R. Parrish, and E.E. Simanek Cytotoxicity hemolysis and acute in vivo toxicity of dendrimers based on melamine candidate vehicles for drug delivery Journal of the American Chemical Society 126 2004 10044 10048
-
(2004)
Journal of the American Chemical Society
, vol.126
, pp. 10044-10048
-
-
Chen, H.T.1
Neerman, M.F.2
Parrish, A.R.3
Simanek, E.E.4
-
52
-
-
80053213011
-
In vivo toxicity of poly(propyleneimine) dendrimers
-
B. Ziemba, A. Janaszewska, K. Ciepluch, M. Krotewicz, W.A. Fogel, D. Appelhans, B. Voit, M. Bryszewska, and B. Klajnert In vivo toxicity of poly(propyleneimine) dendrimers Journal of Biomedical Materials Research Part A 99 2011 261 268
-
(2011)
Journal of Biomedical Materials Research Part A
, vol.99
, pp. 261-268
-
-
Ziemba, B.1
Janaszewska, A.2
Ciepluch, K.3
Krotewicz, M.4
Fogel, W.A.5
Appelhans, D.6
Voit, B.7
Bryszewska, M.8
Klajnert, B.9
-
53
-
-
77952066543
-
Pre-clinical and behavioural toxicity profile of PAMAM dendrimers in mice
-
A.S. Chauhan, N.K. Jain, and P.V. Diwan Pre-clinical and behavioural toxicity profile of PAMAM dendrimers in mice Proceedings of the Royal Society A 466 2010 1535 1550
-
(2010)
Proceedings of the Royal Society A
, vol.466
, pp. 1535-1550
-
-
Chauhan, A.S.1
Jain, N.K.2
Diwan, P.V.3
-
54
-
-
85083125818
-
-
[accessed February 2013, 2012]
-
Anonymous VivaGelÒ. http://www.starpharma.com/vivagel [accessed February 2013, 2012].
-
Anonymous VivaGelÒ
-
-
-
55
-
-
23944434447
-
Dendrimers as drugs: Discovery and preclinical and clinical development of dendrimer-based microbicides for HIV and STI prevention
-
T.D. McCarthy, P. Karellas, S.A. Henderson, M. Giannis, D.F. O'Keefe, G. Heery, J.R.A. Paull, B.R. Matthews, and G. Holan Dendrimers as drugs: discovery and preclinical and clinical development of dendrimer-based microbicides for HIV and STI prevention Molecular Pharmacology 2 2005 312 318
-
(2005)
Molecular Pharmacology
, vol.2
, pp. 312-318
-
-
McCarthy, T.D.1
Karellas, P.2
Henderson, S.A.3
Giannis, M.4
O'Keefe, D.F.5
Heery, G.6
Paull, J.R.A.7
Matthews, B.R.8
Holan, G.9
-
56
-
-
0034981548
-
Pharmacokinetics of Gadomer-17 a new dendritic magnetic resonance contrast agent
-
B. Misselwitz, H. Schmitt-Willich, W. Ebert, T. Frenzelet, and H.J. Weinmann Pharmacokinetics of Gadomer-17 a new dendritic magnetic resonance contrast agent Magnetic Resonance Materials in Physics, Biology and Medicine 12 2011 128 134
-
(2011)
Magnetic Resonance Materials in Physics, Biology and Medicine
, vol.12
, pp. 128-134
-
-
Misselwitz, B.1
Schmitt-Willich, H.2
Ebert, W.3
Frenzelet, T.4
Weinmann, H.J.5
-
57
-
-
0031024171
-
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
-
C.A. Lipinski, F. Lombardo, B.W. Dominy, and P.J. Feeney Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings Advanced Drug Delivery Reviews 23 1997 3 25
-
(1997)
Advanced Drug Delivery Reviews
, vol.23
, pp. 3-25
-
-
Lipinski, C.A.1
Lombardo, F.2
Dominy, B.W.3
Feeney, P.J.4
-
58
-
-
11144320699
-
Navigating chemical space for biology and medicine
-
C.A. Lipinski, and A. Hopkins Navigating chemical space for biology and medicine Nature 432 2004 855 861
-
(2004)
Nature
, vol.432
, pp. 855-861
-
-
Lipinski, C.A.1
Hopkins, A.2
-
59
-
-
0030039619
-
The art and practice of structure-based drug design: A molecular modeling perspective
-
R.S. Bohacek, C. McMartin, and W.C. Guida The art and practice of structure-based drug design: a molecular modeling perspective Medicinal Research Reviews 16 1996 3 50
-
(1996)
Medicinal Research Reviews
, vol.16
, pp. 3-50
-
-
Bohacek, R.S.1
McMartin, C.2
Guida, W.C.3
-
60
-
-
45249123879
-
Structural diversity of organic chemistry. A scaffold analysis of the CAS registry
-
A.H. Lipkus, Q. Yuan, K.A. Lucas, S.A. Funk, W.F. Bartelt, R.J. Schenck, and A.J. Trippe Structural diversity of organic chemistry. A scaffold analysis of the CAS registry Journal of Organic Chemistry 73 2008 4443 4451
-
(2008)
Journal of Organic Chemistry
, vol.73
, pp. 4443-4451
-
-
Lipkus, A.H.1
Yuan, Q.2
Lucas, K.A.3
Funk, S.A.4
Bartelt, W.F.5
Schenck, R.J.6
Trippe, A.J.7
-
61
-
-
82455186157
-
Exploring the chemical space of known and unknown organic small molecules at www.gdb.unibe.ch
-
J.L. Reymond, L.C. Bluma, and R. van Deursen Exploring the chemical space of known and unknown organic small molecules at www.gdb.unibe.ch Chimia 65 2011 863 867
-
(2011)
Chimia
, vol.65
, pp. 863-867
-
-
Reymond, J.L.1
Bluma, L.C.2
Van Deursen, R.3
-
64
-
-
20444378945
-
The principle of complementarity: Chemical versus biological space
-
S.J. Haggarty The principle of complementarity: chemical versus biological space Current Opinion in Chemical Biology 9 2005 296 303
-
(2005)
Current Opinion in Chemical Biology
, vol.9
, pp. 296-303
-
-
Haggarty, S.J.1
-
66
-
-
33645412367
-
Kinase patent space visualization using chemical replacements
-
N.T. Southall Kinase patent space visualization using chemical replacements Journal of Medicinal Chemistry 49 2006 2103 2109
-
(2006)
Journal of Medicinal Chemistry
, vol.49
, pp. 2103-2109
-
-
Southall, N.T.1
-
67
-
-
84862662736
-
Physicochemical descriptor-based scoring scheme for effective and rapid filtering of kinase-like chemical space
-
N. Singh, H. Sun, S. Chaudhury, M.D.M. AbdulHameed, A. Wallqvist, and G.A. Tawa Physicochemical descriptor-based scoring scheme for effective and rapid filtering of kinase-like chemical space Journal of Cheminformatics 4 2012 1 12
-
(2012)
Journal of Cheminformatics
, vol.4
, pp. 1-12
-
-
Singh, N.1
Sun, H.2
Chaudhury, S.3
Abdulhameed, M.D.M.4
Wallqvist, A.5
Tawa, G.A.6
-
68
-
-
0035959985
-
Synthesis of a tetronic acid library focused on inhibitors of tyrosine and dual specificity protein phosphatases and its evaluation regarding VHR and cdc25B inhibition
-
M. Sodeoka Synthesis of a tetronic acid library focused on inhibitors of tyrosine and dual specificity protein phosphatases and its evaluation regarding VHR and cdc25B inhibition Journal of Medicinal Chemistry 44 2001 3216 3222
-
(2001)
Journal of Medicinal Chemistry
, vol.44
, pp. 3216-3222
-
-
Sodeoka, M.1
-
70
-
-
1642389967
-
Countering cooperative effects in protease inhibitors using constrained beta-strand mimicking templates in focused combinatorial libraries
-
R.C. Reid Countering cooperative effects in protease inhibitors using constrained beta-strand mimicking templates in focused combinatorial libraries Journal of Medicinal Chemistry 47 2004 1641 1651
-
(2004)
Journal of Medicinal Chemistry
, vol.47
, pp. 1641-1651
-
-
Reid, R.C.1
-
71
-
-
0037030653
-
Molecular properties that influence the oral bioavailability of drug candidates
-
D.F. Veber, S.R. Johnson, H.Y. Cheng, B.R. Smith, K.W. Ward, and K.D. Kopple Molecular properties that influence the oral bioavailability of drug candidates Journal of Medicinal Chemistry 45 2002 2615 2623
-
(2002)
Journal of Medicinal Chemistry
, vol.45
, pp. 2615-2623
-
-
Veber, D.F.1
Johnson, S.R.2
Cheng, H.Y.3
Smith, B.R.4
Ward, K.W.5
Kopple, K.D.6
-
72
-
-
9744232909
-
Time-related differences in the physical property profiles of oral drugs
-
P.D. Leeson, and A.M. Davis Time-related differences in the physical property profiles of oral drugs Journal of Medicinal Chemistry 47 2004 6338 6348
-
(2004)
Journal of Medicinal Chemistry
, vol.47
, pp. 6338-6348
-
-
Leeson, P.D.1
Davis, A.M.2
-
75
-
-
0036589285
-
Current trends in lead discovery: Are we looking for the appropriate properties
-
T.I. Opera Current trends in lead discovery: are we looking for the appropriate properties Journal of Computer-Aided Molecular Design 16 2002 325 334
-
(2002)
Journal of Computer-Aided Molecular Design
, vol.16
, pp. 325-334
-
-
Opera, T.I.1
-
78
-
-
64549160613
-
Novel chemical space exploration via natural products
-
J. Rosén, J. Gottfries, S. Muresan, A. Backlund, and T.I. Oprea Novel chemical space exploration via natural products Journal of Medicinal Chemistry 52 2009 1953 1962
-
(2009)
Journal of Medicinal Chemistry
, vol.52
, pp. 1953-1962
-
-
Rosén, J.1
Gottfries, J.2
Muresan, S.3
Backlund, A.4
Oprea, T.I.5
-
79
-
-
85083139307
-
Charting navigating and populating natural product chemical space for drug discovery
-
H. Lachance, S. Wetzel, K. Kumar, and H. Waldmann Charting navigating and populating natural product chemical space for drug discovery Journal of Medicinal Chemistry 9 2009 1953 1962
-
(2009)
Journal of Medicinal Chemistry
, vol.9
, pp. 1953-1962
-
-
Lachance, H.1
Wetzel, S.2
Kumar, K.3
Waldmann, H.4
-
80
-
-
85040103085
-
Virtual screening of Chemical Space: From Generic Compound Collections to Tailored Screening Libraries
-
C. Sotriffer, Wiley-VCH Weinbaden
-
M. Boehm Virtual screening of Chemical Space: From Generic Compound Collections to Tailored Screening Libraries C. Sotriffer, Virtual Screening: Principles Challenges and Practical Guidelines 2011 Wiley-VCH Weinbaden 3 34
-
(2011)
Virtual Screening: Principles Challenges and Practical Guidelines
, pp. 3-34
-
-
Boehm, M.1
-
81
-
-
61649109015
-
The influence of lead discovery strategies on the properties of drug candidates
-
G.M. Keserü, and G.M. Makara The influence of lead discovery strategies on the properties of drug candidates Nature Reviews Drug Discovery 8 2009 203 212
-
(2009)
Nature Reviews Drug Discovery
, vol.8
, pp. 203-212
-
-
Keserü, G.M.1
Makara, G.M.2
-
82
-
-
84860359784
-
Finding the sweet spot: The role of nature and nurture in medicinal chemistry
-
M.M. Hann, and G.M. Keserü Finding the sweet spot: the role of nature and nurture in medicinal chemistry Nature Reviews Drug Discovery 11 2012 355 365
-
(2012)
Nature Reviews Drug Discovery
, vol.11
, pp. 355-365
-
-
Hann, M.M.1
Keserü, G.M.2
-
83
-
-
79960990847
-
Chemical and structural lessons from recent successes in protein-protein interaction inhibition (2P2I)
-
X. Morelli, R. Bourgeas, and P. Roche Chemical and structural lessons from recent successes in protein-protein interaction inhibition (2P2I) Current Opinion in Chemical Biology 15 2011 1 7
-
(2011)
Current Opinion in Chemical Biology
, vol.15
, pp. 1-7
-
-
Morelli, X.1
Bourgeas, R.2
Roche, P.3
-
84
-
-
84856201851
-
Quantifying the chemical beauty of drugs
-
G.R. Bickerton, G.V. Paolini, J. Besnard, S. Muresan, and A.L. Hopkins Quantifying the chemical beauty of drugs Nature Chemistry 4 2012 90 98
-
(2012)
Nature Chemistry
, vol.4
, pp. 90-98
-
-
Bickerton, G.R.1
Paolini, G.V.2
Besnard, J.3
Muresan, S.4
Hopkins, A.L.5
-
86
-
-
79955575780
-
The rule of five for non-oral routes of drug delivery: Ophthalmic inhalation and transdermal
-
Y.B. Choy, and M.R. Prausnitz The rule of five for non-oral routes of drug delivery: ophthalmic inhalation and transdermal Pharmaceutical Research 28 2011 943 948
-
(2011)
Pharmaceutical Research
, vol.28
, pp. 943-948
-
-
Choy, Y.B.1
Prausnitz, M.R.2
-
87
-
-
0033025637
-
Chance favors the prepared mind - From serendipity to rational drug design
-
H. Kubinyi Chance favors the prepared mind - from serendipity to rational drug design Journal of Receptors and Signal Transduction Research 19 1999 15 39
-
(1999)
Journal of Receptors and Signal Transduction Research
, vol.19
, pp. 15-39
-
-
Kubinyi, H.1
-
89
-
-
71249135977
-
Exploring novel chemical space through the use of computational and structural biology
-
A.C. Rigby Exploring novel chemical space through the use of computational and structural biology Combinatorial Chemistry and High Throughput Screening 12 2009 927 928
-
(2009)
Combinatorial Chemistry and High Throughput Screening
, vol.12
, pp. 927-928
-
-
Rigby, A.C.1
-
90
-
-
82955213501
-
Towards the systematic exploration of chemical space
-
M. Dow, M. Fisher, T. James, F. Marchetti, and A. Nelson Towards the systematic exploration of chemical space Organic & Biomolecular Chemistry 10 2012 17 28
-
(2012)
Organic & Biomolecular Chemistry
, vol.10
, pp. 17-28
-
-
Dow, M.1
Fisher, M.2
James, T.3
Marchetti, F.4
Nelson, A.5
-
92
-
-
0036603905
-
Chemical space navigation in lead discovery
-
T.I. Oprea Chemical space navigation in lead discovery Current Opinion in Chemical Biology 6 2002 384 389
-
(2002)
Current Opinion in Chemical Biology
, vol.6
, pp. 384-389
-
-
Oprea, T.I.1
-
93
-
-
11144311139
-
Lessons from natural molecules
-
J. Clardy, and C. Walsh Lessons from natural molecules Nature 432 2004 829 837
-
(2004)
Nature
, vol.432
, pp. 829-837
-
-
Clardy, J.1
Walsh, C.2
-
94
-
-
20444420189
-
Natural product-like chemical space: Search for chemical dissectors of macromolecular interactions
-
A. Reayi, and P. Arya Natural product-like chemical space: search for chemical dissectors of macromolecular interactions Current Opinion in Chemical Biology 9 2005 240 247
-
(2005)
Current Opinion in Chemical Biology
, vol.9
, pp. 240-247
-
-
Reayi, A.1
Arya, P.2
-
96
-
-
11144323163
-
Virtual screening of chemical libraries
-
B.K. Shoichet Virtual screening of chemical libraries Nature 432 2004 862 865
-
(2004)
Nature
, vol.432
, pp. 862-865
-
-
Shoichet, B.K.1
-
98
-
-
34247194965
-
Virtual exploration of the chemical universe up to 11 atoms of C, N, O, F: Assembly of 26.4 million structures (110.9 million stereoisomers) and analysis for new ring systems, stereochemistry, physicochemical properties, compound classes, and drug discovery
-
T. Fink, and J.L. Reymond Virtual exploration of the chemical universe up to 11 atoms of C, N, O, F: assembly of 26.4 million structures (110.9 million stereoisomers) and analysis for new ring systems, stereochemistry, physicochemical properties, compound classes, and drug discovery Journal of Chemical Information and Modeling 47 2007 342 353
-
(2007)
Journal of Chemical Information and Modeling
, vol.47
, pp. 342-353
-
-
Fink, T.1
Reymond, J.L.2
-
100
-
-
67649619336
-
970 Million drug like small molecules for virtual screening in the chemical universe database GDB-13
-
L.C. Blum, and J.L. Reymond 970 Million drug like small molecules for virtual screening in the chemical universe database GDB-13 Journal of the American Chemical Society 131 2009 8732 8733
-
(2009)
Journal of the American Chemical Society
, vol.131
, pp. 8732-8733
-
-
Blum, L.C.1
Reymond, J.L.2
-
101
-
-
34447548576
-
Ligand efficiency indices for effective drug discovery
-
C. Abad-Zapatero Ligand efficiency indices for effective drug discovery Expert Opinion on Drug Discovery 2 2007 469 488
-
(2007)
Expert Opinion on Drug Discovery
, vol.2
, pp. 469-488
-
-
Abad-Zapatero, C.1
-
102
-
-
77953693716
-
Drug efficiency: A new concept to guide lead optimization programs towards the selection of better clinical candidates
-
S. Braggio, D. Montanari, T. Rossi, and E. Ratti Drug efficiency: a new concept to guide lead optimization programs towards the selection of better clinical candidates Expert Opinion on Drug Discovery 5 2010 609 618
-
(2010)
Expert Opinion on Drug Discovery
, vol.5
, pp. 609-618
-
-
Braggio, S.1
Montanari, D.2
Rossi, T.3
Ratti, E.4
-
103
-
-
77957682613
-
Ligand efficiency indices for an effective mapping of chemico-biological space: The concept of an atlas-like representation
-
C. AbadZapatero, O. Perisic, J. Wass, A.P. Bento, J. Overington, B. Al-Lazikani, and M.E. Johnson Ligand efficiency indices for an effective mapping of chemico-biological space: the concept of an atlas-like representation Drug Discovery Today 15 2010 804 811
-
(2010)
Drug Discovery Today
, vol.15
, pp. 804-811
-
-
Abadzapatero, C.1
Perisic, O.2
Wass, J.3
Bento, A.P.4
Overington, J.5
Al-Lazikani, B.6
Johnson, M.E.7
-
105
-
-
34250840722
-
Multiplication of human natural killer cells by nanosized phosphonate-capped dendrimers
-
L. Griffe, M. Poupot, P. Marchand, A. Maraval, C.O. Turrin, O. Rolland, P. Metivier, G. Bacquet, J.J. Fournie, A.M. Caminade, R. Poupot, and J.P. Majoral Multiplication of human natural killer cells by nanosized phosphonate-capped dendrimers Angewandte Chemie International Edition 46 2007 2523 2526
-
(2007)
Angewandte Chemie International Edition
, vol.46
, pp. 2523-2526
-
-
Griffe, L.1
Poupot, M.2
Marchand, P.3
Maraval, A.4
Turrin, C.O.5
Rolland, O.6
Metivier, P.7
Bacquet, G.8
Fournie, J.J.9
Caminade, A.M.10
Poupot, R.11
Majoral, J.P.12
-
106
-
-
53849132384
-
Tailored control and optimisation of the number of phosphonic acid termini on phosphorus-containing dendrimers for the ex-vivo activation of human monocytes
-
O. Rolland, L. Griffe, M. Poupot, A. Maraval, A. Ouali, Coppel y, J.J. Fournie, G. Bacquet, C.O. Turrin, A.M. Caminade, J.P. Majoral, and R. Poupot Tailored control and optimisation of the number of phosphonic acid termini on phosphorus-containing dendrimers for the ex-vivo activation of human monocytes Chemistry: A European Journal 14 2008 4836 4850
-
(2008)
Chemistry: A European Journal
, vol.14
, pp. 4836-4850
-
-
Rolland, O.1
Griffe, L.2
Poupot, M.3
Maraval, A.4
Ouali, A.5
Coppel, Y.6
Fournie, J.J.7
Bacquet, G.8
Turrin, C.O.9
Caminade, A.M.10
Majoral, J.P.11
Poupot, R.12
-
107
-
-
0038495929
-
Optimisation of dendrimer-mediated gene transfer by anionic oligomers
-
A.V. Maksimenko, V. Mandrouguine, M.B. Gottikh, J.R. Bertrand, J.P. Majoral, and C. Malvy Optimisation of dendrimer-mediated gene transfer by anionic oligomers Journal of Gene Medicine 5 2003 61 71
-
(2003)
Journal of Gene Medicine
, vol.5
, pp. 61-71
-
-
Maksimenko, A.V.1
Mandrouguine, V.2
Gottikh, M.B.3
Bertrand, J.R.4
Majoral, J.P.5
Malvy, C.6
-
108
-
-
72149094058
-
Designing dendrimers for ocular drug delivery
-
G. Spataro, F. Malecaze, C.O. Turrin, V. Soler, C. Duhayon, P.P. Elena, J.P. Majoral, and A.M. Caminade Designing dendrimers for ocular drug delivery European Journal of Medical Chemistry 45 2010 326 334
-
(2010)
European Journal of Medical Chemistry
, vol.45
, pp. 326-334
-
-
Spataro, G.1
Malecaze, F.2
Turrin, C.O.3
Soler, V.4
Duhayon, C.5
Elena, P.P.6
Majoral, J.P.7
Caminade, A.M.8
-
109
-
-
33746288083
-
Water-soluble dendrimeric two-photons tracers for in vivo imaging
-
R.K. Thatavarathy, M. Parent, M.V.H. Werts, L. Moreaux, S. Gmouh, S. Charpak, A.M. Caminade, J.P. Majoral, and M. Blanchard-Desce Water-soluble dendrimeric two-photons tracers for In vivo imaging Angewandte Chemie International Edition 45 2006 4645 4648
-
(2006)
Angewandte Chemie International Edition
, vol.45
, pp. 4645-4648
-
-
Thatavarathy, R.K.1
Parent, M.2
Werts, M.V.H.3
Moreaux, L.4
Gmouh, S.5
Charpak, S.6
Caminade, A.M.7
Majoral, J.P.8
Blanchard-Desce, M.9
-
110
-
-
79955703641
-
A Phosphorus-based dendrimer targets inflammation and osteoclastogenesis in experimental arthritis
-
M. Hayder, M. Poupot, M. Baron, D. Nigon, C.O. Turrin, A.M. Caminade, J.P. Majoral, R.A. Eisenberg, J.J. Fournie, A. Cantagrel, R. Poupot, and J.L. Davignon A Phosphorus-based dendrimer targets inflammation and osteoclastogenesis in experimental arthritis Science Translational Medicine 3 81ra35/ 2011 1 11
-
(2011)
Science Translational Medicine
, vol.3
, Issue.81 RA35
, pp. 1-11
-
-
Hayder, M.1
Poupot, M.2
Baron, M.3
Nigon, D.4
Turrin, C.O.5
Caminade, A.M.6
Majoral, J.P.7
Eisenberg, R.A.8
Fournie, J.J.9
Cantagrel, A.10
Poupot, R.11
Davignon, J.L.12
-
111
-
-
67650698519
-
Versatile conjugation of octreotide to dendrimers by cycloaddition ("click") chemistry to yield high-affinity multivalent cyclic Peptide dendrimers
-
C.B. Yim, O.C. Boerman, M. de Visser, M. de Jong, A.C. Dechesne, D.T. Rijkers, and R.M. Liskamp Versatile conjugation of octreotide to dendrimers by cycloaddition ("click") chemistry to yield high-affinity multivalent cyclic Peptide dendrimers Bioconjugate Chemistry 20 2009 1323 1331
-
(2009)
Bioconjugate Chemistry
, vol.20
, pp. 1323-1331
-
-
Yim, C.B.1
Boerman, O.C.2
De Visser, M.3
De Jong, M.4
Dechesne, A.C.5
Rijkers, D.T.6
Liskamp, R.M.7
-
112
-
-
0030292260
-
Self-assembly of cyclic peptides on a dendrimer: Multiple cyclic antigen peptides
-
J.C. Spetzler, and J.P. Tam Self-assembly of cyclic peptides on a dendrimer: multiple cyclic antigen peptides Peptide Research 9 1996 290 296
-
(1996)
Peptide Research
, vol.9
, pp. 290-296
-
-
Spetzler, J.C.1
Tam, J.P.2
-
114
-
-
59549093153
-
Polycationic phosphorus dendrimers: Synthesis characterization study of cytotoxicity complexation of DNA and transfection experiments
-
C. Padié, M. Maszewska, K. Majchrzak, B. Nawrot, A.M. Caminade, and J.P. Majoral Polycationic phosphorus dendrimers: synthesis characterization study of cytotoxicity complexation of DNA and transfection experiments New Journal of Chemistry 33 2009 318 326
-
(2009)
New Journal of Chemistry
, vol.33
, pp. 318-326
-
-
Padié, C.1
Maszewska, M.2
Majchrzak, K.3
Nawrot, B.4
Caminade, A.M.5
Majoral, J.P.6
-
115
-
-
79959267067
-
Synthesis of PAMAM dendrimer derivatives with enhanced buffering capacity and remarkable gene transfection efficiency
-
G.S. Yu, Y.M. Bae, H. Choi, B. Kong, I.S. Choi, and J.S. Choi Synthesis of PAMAM dendrimer derivatives with enhanced buffering capacity and remarkable gene transfection efficiency Bioconjugate Chemistry 22 2011 1046 1055
-
(2011)
Bioconjugate Chemistry
, vol.22
, pp. 1046-1055
-
-
Yu, G.S.1
Bae, Y.M.2
Choi, H.3
Kong, B.4
Choi, I.S.5
Choi, J.S.6
-
116
-
-
0027655718
-
Polyamidoamine cascade polymers mediate efficient transfection of cells in culture
-
J. Haensler, C. Francis, and F.C. Szoka Polyamidoamine cascade polymers mediate efficient transfection of cells in culture Bioconjugate Chemistry 4 1993 372 379
-
(1993)
Bioconjugate Chemistry
, vol.4
, pp. 372-379
-
-
Haensler, J.1
Francis, C.2
Szoka, F.C.3
-
117
-
-
0029945799
-
Regulation of in vitro gene expression using antisense oligonucleotides or antisense expression plasmids transfected using starburst PAMAM dendrimers
-
A. Bielinska, J.F. Kukowska-Latallo, J. Johnson, D.A. Tomalia, and J.R. Baker Regulation of in vitro gene expression using antisense oligonucleotides or antisense expression plasmids transfected using starburst PAMAM dendrimers Nucleic Acids Research 24 1996 2176 2182
-
(1996)
Nucleic Acids Research
, vol.24
, pp. 2176-2182
-
-
Bielinska, A.1
Kukowska-Latallo, J.F.2
Johnson, J.3
Tomalia, D.A.4
Baker, J.R.5
-
118
-
-
0033404268
-
PAMAM dendrimers as delivery agents for antisense oligonucleotides
-
H. Yoo, P. Sazani, and R.L. Juliano PAMAM dendrimers as delivery agents for antisense oligonucleotides Pharmaceutical Research 16 1999 1799 1804
-
(1999)
Pharmaceutical Research
, vol.16
, pp. 1799-1804
-
-
Yoo, H.1
Sazani, P.2
Juliano, R.L.3
-
120
-
-
79957582182
-
Dendrimers-delivered short hairpin RNA targeting hTERT inhibits oral cancer cell growth in vitro and in vivo
-
X. Liu, H. Huang, J. Wang, C. Wang, M. Wang, B. Zhang, and C. Pan Dendrimers-delivered short hairpin RNA targeting hTERT inhibits oral cancer cell growth in vitro and in vivo Biochemical Pharmacology 82 2011 17 23
-
(2011)
Biochemical Pharmacology
, vol.82
, pp. 17-23
-
-
Liu, X.1
Huang, H.2
Wang, J.3
Wang, C.4
Wang, M.5
Zhang, B.6
Pan, C.7
-
121
-
-
79952972079
-
Multifunctional triblock nanocarrier (PAMAM-PEG-PLL) for the efficient intracellular siRNA delivery and gene silencing
-
M.L. Patil, M. Zhang, and T. Minko Multifunctional triblock nanocarrier (PAMAM-PEG-PLL) for the efficient intracellular siRNA delivery and gene silencing ACS Nano 5 2011 1877 1887
-
(2011)
ACS Nano
, vol.5
, pp. 1877-1887
-
-
Patil, M.L.1
Zhang, M.2
Minko, T.3
-
122
-
-
79953859821
-
Efficient non-toxic hybrid PPV-PAMAM dendrimer as a gene carrier for neuronal cells
-
A.C. Rodrigo, I. Rivilla, F.C. Pérez-Martínez, S. Monteagudo, V. Ocaña, J. Guerra, J.C. García-Martínez, S. Merino, P. Sánchez-Verdú, V. Ceña, and J. Rodríguez-López Efficient non-toxic hybrid PPV-PAMAM dendrimer as a gene carrier for neuronal cells Biomacromolecules 12 2011 1205 1213
-
(2011)
Biomacromolecules
, vol.12
, pp. 1205-1213
-
-
Rodrigo, A.C.1
Rivilla, I.2
Pérez-Martínez, F.C.3
Monteagudo, S.4
Ocaña, V.5
Guerra, J.6
García-Martínez, J.C.7
Merino, S.8
Sánchez-Verdú, P.9
Ceña, V.10
Rodríguez-López, J.11
-
123
-
-
84863116554
-
SiRNA delivery systems based on neutral cross-linked dendrimers
-
J. Liu, J. Zhou, and Y. Luo SiRNA delivery systems based on neutral cross-linked dendrimers Bioconjugate Chemistry 23 2012 174 183
-
(2012)
Bioconjugate Chemistry
, vol.23
, pp. 174-183
-
-
Liu, J.1
Zhou, J.2
Luo, Y.3
-
124
-
-
42949087378
-
Antibody-dendrimer conjugates: The number not the size of the dendrimers determines the immunoreactivity
-
C. Wängler, G. Moldenhauer, M. Eisenhut, U. Haberkorn, and W. Mier Antibody-dendrimer conjugates: the number not the size of the dendrimers determines the immunoreactivity Bioconjugate Chemistry 19 2008 813 820
-
(2008)
Bioconjugate Chemistry
, vol.19
, pp. 813-820
-
-
Wängler, C.1
Moldenhauer, G.2
Eisenhut, M.3
Haberkorn, U.4
Mier, W.5
-
125
-
-
84863230506
-
Preparation of cystamine core dendrimer and anti-body-dendrimer conjugates for RMI angiography
-
K. New, D.E. Milenic, G.L. Ray, Y.S. Kim, and M.W. Brechbiel Preparation of cystamine core dendrimer and anti-body-dendrimer conjugates for RMI angiography Molecular Pharmaceutics 9 2012 374 381
-
(2012)
Molecular Pharmaceutics
, vol.9
, pp. 374-381
-
-
New, K.1
Milenic, D.E.2
Ray, G.L.3
Kim, Y.S.4
Brechbiel, M.W.5
-
126
-
-
9744248297
-
In vitro targeting of synthesized antibody-conjugated dendrimer nanoparticles
-
T.P. Thomas, A.K. Patri, A. Myc, M.T. Myaing, J.Y. Ye, T.B. Norris, and J.R. Baker In vitro targeting of synthesized antibody-conjugated dendrimer nanoparticles Biomacromolecules 5 2004 2269 2274
-
(2004)
Biomacromolecules
, vol.5
, pp. 2269-2274
-
-
Thomas, T.P.1
Patri, A.K.2
Myc, A.3
Myaing, M.T.4
Ye, J.Y.5
Norris, T.B.6
Baker, J.R.7
-
127
-
-
80054681184
-
Targeted chemoimmunotherapy using drug-loaded aptamer-dendrimer bioconjugates
-
I.H. Lee, S. An, M.K. Yu, H.K. Kwon, S.H. Im, and S. Jon Targeted chemoimmunotherapy using drug-loaded aptamer-dendrimer bioconjugates Journal of Controlled Release 7 2011 435 441
-
(2011)
Journal of Controlled Release
, vol.7
, pp. 435-441
-
-
Lee, I.H.1
An, S.2
Yu, M.K.3
Kwon, H.K.4
Im, S.H.5
Jon, S.6
-
128
-
-
63949086284
-
Highly efficient transfection of rat cortical neurons using carbosilane dendrimers unveils a neuroprotective role for HIF-1alpha in early chemical hypoxia-mediated neurotoxicity
-
I. Posadas, B. López-Hernández, M.I. Clemente, J.L. Jiménez, P. Ortega, P.J. de la Mata, R. Gómez, M.A. Muñoz-Fernández, and V. Ceña Highly efficient transfection of rat cortical neurons using carbosilane dendrimers unveils a neuroprotective role for HIF-1alpha in early chemical hypoxia-mediated neurotoxicity Pharmaceutical Research 26 2009 1181 1191
-
(2009)
Pharmaceutical Research
, vol.26
, pp. 1181-1191
-
-
Posadas, I.1
López-Hernández, B.2
Clemente, M.I.3
Jiménez, J.L.4
Ortega, P.5
De La Mata, P.J.6
Gómez, R.7
Muñoz-Fernández, M.A.8
Ceña, V.9
-
129
-
-
33746415181
-
Enhanced transfection of primary cortical cultures using arginine-grafted PAMAM dendrimer PAMAM-Arg
-
J.B. Kim, J.S. Choi, K. Nam, M. Lee, J.S. Park, and J.K. Lee Enhanced transfection of primary cortical cultures using arginine-grafted PAMAM dendrimer PAMAM-Arg Journal of Controlled Release 114 2006 110 117
-
(2006)
Journal of Controlled Release
, vol.114
, pp. 110-117
-
-
Kim, J.B.1
Choi, J.S.2
Nam, K.3
Lee, M.4
Park, J.S.5
Lee, J.K.6
-
131
-
-
84884790598
-
Dendrimer-coated carbohydrates as drug delivery Trojan horses in glycosciences
-
Y.Y. Cheng, Wiley-VCH Weinheim
-
Y.M. Chabre, and R. Roy Dendrimer-coated carbohydrates as drug delivery Trojan horses in glycosciences Y.Y. Cheng, Dendrimer-based Drug delivery Systems: From Theory to Practice 2012 Wiley-VCH Weinheim 405 436
-
(2012)
Dendrimer-based Drug Delivery Systems: From Theory to Practice
, pp. 405-436
-
-
Chabre, Y.M.1
Roy, R.2
-
132
-
-
84856735496
-
Glycodendrimers as functional antigens and antitumorales vaccines
-
R. Roy, and T.C. Shiao Glycodendrimers as functional antigens and antitumorales vaccines New Journal of Chemistry 36 2012 324 339
-
(2012)
New Journal of Chemistry
, vol.36
, pp. 324-339
-
-
Roy, R.1
Shiao, T.C.2
-
133
-
-
52949100596
-
Recent trends in glycodendrimer syntheses and applications
-
Y.M. Chabre, and R.R. Roy Recent trends in glycodendrimer syntheses and applications Current Topics in Medicinal Chemistry 14 2008 1237 1285
-
(2008)
Current Topics in Medicinal Chemistry
, vol.14
, pp. 1237-1285
-
-
Chabre, Y.M.1
Roy, R.R.2
-
134
-
-
33845655459
-
Design of phosphorylated dendritic architectures to promote human monocyte activation
-
M. Poupot, L. Griffe, P. Marchand, A. Maraval, O. Rolland, L. Martinet, F.E. L'Faqihi-Olive, C.O. Turrin, A.M. Caminade, J.J. Fournié, J.P. Majoral, and R. Poupot Design of phosphorylated dendritic architectures to promote human monocyte activation FASEB Journal 20 2006 2339 2351
-
(2006)
FASEB Journal
, vol.20
, pp. 2339-2351
-
-
Poupot, M.1
Griffe, L.2
Marchand, P.3
Maraval, A.4
Rolland, O.5
Martinet, L.6
L'Faqihi-Olive, F.E.7
Turrin, C.O.8
Caminade, A.M.9
Fournié, J.J.10
Majoral, J.P.11
Poupot, R.12
-
135
-
-
1542509564
-
The use of a dendrimer propranolol prodrug to bypass efflux transporters and enhance oral bioavailability
-
A. D'Emanuel, R. Jevprasesphant, J. Penny, and D. Attwood The use of a dendrimer propranolol prodrug to bypass efflux transporters and enhance oral bioavailability Journal of Controlled Release 95 2004 447 453
-
(2004)
Journal of Controlled Release
, vol.95
, pp. 447-453
-
-
D'Emanuel, A.1
Jevprasesphant, R.2
Penny, J.3
Attwood, D.4
-
136
-
-
39749200864
-
Methotrexate loaded polyether- copolyester dendrimers for the treatment of gliomas: Enhanced efficacy and intratumoral transport capability
-
R.S. Dhanikula, A. Argaw, J.F. Bouchard, and P. Hildgen Methotrexate loaded polyether- copolyester dendrimers for the treatment of gliomas: enhanced efficacy and intratumoral transport capability Molecular Pharmaceutics 5 2008 105 116
-
(2008)
Molecular Pharmaceutics
, vol.5
, pp. 105-116
-
-
Dhanikula, R.S.1
Argaw, A.2
Bouchard, J.F.3
Hildgen, P.4
-
137
-
-
75849149510
-
Synthesis and antioxidant properties of enone core based dendrimers with carbazole as surface group
-
P. Rajakumar, N. Venkatesan, K. Sekar, S. Nagaraj, and R. Rengasamy Synthesis and antioxidant properties of enone core based dendrimers with carbazole as surface group European Journal of Medical Chemistry 45 2010 1220 1224
-
(2010)
European Journal of Medical Chemistry
, vol.45
, pp. 1220-1224
-
-
Rajakumar, P.1
Venkatesan, N.2
Sekar, K.3
Nagaraj, S.4
Rengasamy, R.5
-
138
-
-
38349134916
-
Dendrimers as drug carriers: Applications in different routes of drug administration
-
Y. Cheng, Z. Xu, M. MA, and T. Xu Dendrimers as drug carriers: applications in different routes of drug administration Journal of Pharmaceutical Sciences 97 2008 123 143
-
(2008)
Journal of Pharmaceutical Sciences
, vol.97
, pp. 123-143
-
-
Cheng, Y.1
Xu, Z.2
Ma, M.3
Xu, T.4
-
139
-
-
58149101458
-
Dendrimeric nanoarchitectures mediated transdermal and oral delivery of bioactives
-
V. Gajbhiye, P.V. Kumar, A. Sharma, A. Agarwal, A. Asthana, and N.K. Jain Dendrimeric nanoarchitectures mediated transdermal and oral delivery of bioactives Indian Journal of Pharmaceutical Sciences 70 2008 431 439
-
(2008)
Indian Journal of Pharmaceutical Sciences
, vol.70
, pp. 431-439
-
-
Gajbhiye, V.1
Kumar, P.V.2
Sharma, A.3
Agarwal, A.4
Asthana, A.5
Jain, N.K.6
-
140
-
-
84859338068
-
Dendrimer-mediated drug delivery to the skin
-
M. Sun, A. Fan, Z. Wang, and Y. Zhao Dendrimer-mediated drug delivery to the skin Soft Matter 8 2012 4301 4305
-
(2012)
Soft Matter
, vol.8
, pp. 4301-4305
-
-
Sun, M.1
Fan, A.2
Wang, Z.3
Zhao, Y.4
-
141
-
-
42349094203
-
Nanoparticles in medicine: Therapeutic applications and developments
-
I. Zhang, F.X. Gu, J.M. Chan, A.Z. Wang, R.S. Langer, and O.C. Farokhzad Nanoparticles in medicine: therapeutic applications and developments Journal of Translational Medicine 5 2008 761 769
-
(2008)
Journal of Translational Medicine
, vol.5
, pp. 761-769
-
-
Zhang, I.1
Gu, F.X.2
Chan, J.M.3
Wang, A.Z.4
Langer, R.S.5
Farokhzad, O.C.6
-
142
-
-
67349190954
-
The chemist as astronaut: Searching for biologically useful space in the chemical universe
-
D.J. Triggle The chemist as astronaut: searching for biologically useful space in the chemical universe Biochemical Pharmacology 78 2009 217 223
-
(2009)
Biochemical Pharmacology
, vol.78
, pp. 217-223
-
-
Triggle, D.J.1
-
143
-
-
77955517509
-
Druggable pockets and binding site centric chemical space: A paradigm shift in drug discovery
-
S. Pérot, O. Sperandio, M.A. Miteva, A.C. Camproux, and B.O. Villoutreix Druggable pockets and binding site centric chemical space: a paradigm shift in drug discovery Drug Discovery Today 15 2010 656 667
-
(2010)
Drug Discovery Today
, vol.15
, pp. 656-667
-
-
Pérot, S.1
Sperandio, O.2
Miteva, M.A.3
Camproux, A.C.4
Villoutreix, B.O.5
-
144
-
-
78649254350
-
Accessing new chemical space for 'undruggable' targets
-
S. Dandapani, and L.A. Marcaurelle Accessing new chemical space for 'undruggable' targets Nature Chemical Biology 6 2010 861 863
-
(2010)
Nature Chemical Biology
, vol.6
, pp. 861-863
-
-
Dandapani, S.1
Marcaurelle, L.A.2
-
145
-
-
77749283338
-
Design of stimuli-responsive dendrimers
-
C. Kojima Design of stimuli-responsive dendrimers Expert Opinion on Drug Discovery 7 2010 307 319
-
(2010)
Expert Opinion on Drug Discovery
, vol.7
, pp. 307-319
-
-
Kojima, C.1
-
147
-
-
54049134708
-
The design structures and therapeutic potential of protein epitope mimetics
-
J.A. Robinson, S. DeMarco, F. Gombert, K. Moehle, and D. Obrecht The design structures and therapeutic potential of protein epitope mimetics Drug Discovery Today 13 2008 944 951
-
(2008)
Drug Discovery Today
, vol.13
, pp. 944-951
-
-
Robinson, J.A.1
Demarco, S.2
Gombert, F.3
Moehle, K.4
Obrecht, D.5
-
148
-
-
76149109071
-
Targeting protein-protein interactions for therapeutic intervention: A challenge for the future
-
G. Zinzalla, and D.E. Thurstoon Targeting protein-protein interactions for therapeutic intervention: a challenge for the future Future Medicinal Chemistry 1 2009 65 93
-
(2009)
Future Medicinal Chemistry
, vol.1
, pp. 65-93
-
-
Zinzalla, G.1
Thurstoon, D.E.2
-
149
-
-
33645469420
-
Peptide peptidomimetic and small-molecule antagonists of the p53-HDM2 protein-protein interaction
-
P.M. Fischer Peptide peptidomimetic and small-molecule antagonists of the p53-HDM2 protein-protein interaction International Journal of Peptide Research and Therapeutics 12 2006 3 19
-
(2006)
International Journal of Peptide Research and Therapeutics
, vol.12
, pp. 3-19
-
-
Fischer, P.M.1
-
150
-
-
33645827371
-
Targeting protein-protein interactions by rational design: Mimicry of protein surfaces
-
S. Fletcher, and A.D. Hamilton Targeting protein-protein interactions by rational design: mimicry of protein surfaces Journal of the Royal Society Interface 3 2006 215 233
-
(2006)
Journal of the Royal Society Interface
, vol.3
, pp. 215-233
-
-
Fletcher, S.1
Hamilton, A.D.2
-
151
-
-
0034278978
-
Quaternary ammonium functionalized poly(propylene imine) dendrimers as effective antimicrobials: Srtructure-activity studies
-
C.Z. Chen, N.C. Beck-Tan, P. Dhurjati, T.K. van Dyk, R.A. LaRossa, and S.L. Cooper Quaternary ammonium functionalized poly(propylene imine) dendrimers as effective antimicrobials: srtructure-activity studies Biomacromolecules 1 2000 473 480
-
(2000)
Biomacromolecules
, vol.1
, pp. 473-480
-
-
Chen, C.Z.1
Beck-Tan, N.C.2
Dhurjati, P.3
Van Dyk, T.K.4
Larossa, R.A.5
Cooper, S.L.6
-
152
-
-
0009882170
-
Incorporation of dimethyldodecylammonium chloride functionalities onto poly(propylene imine) dendrimers significantly enhances their antibacterial properties
-
C.Z. Chen, S.L. Cooper, and N.C.B. Tan Incorporation of dimethyldodecylammonium chloride functionalities onto poly(propylene imine) dendrimers significantly enhances their antibacterial properties Chemical Communications 1999 1585 1586
-
(1999)
Chemical Communications
, pp. 1585-1586
-
-
Chen, C.Z.1
Cooper, S.L.2
Tan, N.C.B.3
-
153
-
-
70349339347
-
Antibacterial activity and cytotoxicity of PEGylated poly(amidoamine) dendrimers
-
A.I. Lopez, R.Y. Reins, A.M. McDermott, B.W. Trautner, and C. Cai Antibacterial activity and cytotoxicity of PEGylated poly(amidoamine) dendrimers Molecular BioSystems 5 2009 1148 1156
-
(2009)
Molecular BioSystems
, vol.5
, pp. 1148-1156
-
-
Lopez, A.I.1
Reins, R.Y.2
McDermott, A.M.3
Trautner, B.W.4
Cai, C.5
-
154
-
-
34347338838
-
Antibacterial activities of poly(amidoamine) dendrimers terminated with amino and poly(ethylene glycol) groups
-
M.K. Calabretta, A. Kumar, A.M. McDermott, and C. Cai Antibacterial activities of poly(amidoamine) dendrimers terminated with amino and poly(ethylene glycol) groups Biomacromolecules 8 2007 1807 1811
-
(2007)
Biomacromolecules
, vol.8
, pp. 1807-1811
-
-
Calabretta, M.K.1
Kumar, A.2
McDermott, A.M.3
Cai, C.4
-
155
-
-
77954315628
-
Inhibition of bacterial growth and intramniotic infection in a guinea pig model of chorioamnionitis using PAMAM dendrimers
-
W.R.S. Navath, A.R. Menjoge, B. Balakrishanan, R. Bellair, H. Dai, R. Romero, S. Kannan, and R.M. Kannan Inhibition of bacterial growth and intramniotic infection in a guinea pig model of chorioamnionitis using PAMAM dendrimers International Journal of Pharmaceutics 395 2010 298 308
-
(2010)
International Journal of Pharmaceutics
, vol.395
, pp. 298-308
-
-
Navath, W.R.S.1
Menjoge, A.R.2
Balakrishanan, B.3
Bellair, R.4
Dai, H.5
Romero, R.6
Kannan, S.7
Kannan, R.M.8
-
157
-
-
55549122686
-
Anionic amphiphilic dendrimers as antibacterial agents
-
S.R. Meyers, F.S. Juhn, A.P. Griset, N.R. Luman, and M.W. Grinstaff Anionic amphiphilic dendrimers as antibacterial agents Journal of the American Chemical Society 130 2008 14444 14445
-
(2008)
Journal of the American Chemical Society
, vol.130
, pp. 14444-14445
-
-
Meyers, S.R.1
Juhn, F.S.2
Griset, A.P.3
Luman, N.R.4
Grinstaff, M.W.5
-
158
-
-
18744371942
-
Synthesis and bactericidal efficacy of novel dendrimers
-
P. Rajakumar, K. Ganesan, S. Jayavelu, and K. Murugesan Synthesis and bactericidal efficacy of novel dendrimers Synlett 7 2005 1121 1124
-
(2005)
Synlett
, vol.7
, pp. 1121-1124
-
-
Rajakumar, P.1
Ganesan, K.2
Jayavelu, S.3
Murugesan, K.4
-
159
-
-
52649166244
-
Amine and ammonium functionalization of chloromethylsilane- endeddendrimers. Antimicrobial activity studies
-
P. Ortega, J.L. Copa-Patino, M.A. Munoz-Fernandez, J. Soliveri, R. Gomez, and J. Javier de la Mata Amine and ammonium functionalization of chloromethylsilane-endeddendrimers. Antimicrobial activity studies Organic & Biomolecular Chemistry 6 2008 3264 3269
-
(2008)
Organic & Biomolecular Chemistry
, vol.6
, pp. 3264-3269
-
-
Ortega, P.1
Copa-Patino, J.L.2
Munoz-Fernandez, M.A.3
Soliveri, J.4
Gomez, R.5
Javier De La Mata, J.6
-
160
-
-
79959779806
-
Hyperbranched polymers versus dendrimers containing a carbosilane framework and terminal ammonium groups as antimicrobial agents
-
P. Ortega, B.M. Cobaleda, J.M. Hernandez-Ros, E. Fuentes-Paniagua, J. Sanchez-Nieves, M.P. Tarazona, J.L. Copa-Patino, J. Soliveri, F. Javier de la Mata, and R. Gomez Hyperbranched polymers versus dendrimers containing a carbosilane framework and terminal ammonium groups as antimicrobial agents Organic & Biomolecular Chemistry 9 2011 5238 5248
-
(2011)
Organic & Biomolecular Chemistry
, vol.9
, pp. 5238-5248
-
-
Ortega, P.1
Cobaleda, B.M.2
Hernandez-Ros, J.M.3
Fuentes-Paniagua, E.4
Sanchez-Nieves, J.5
Tarazona, M.P.6
Copa-Patino, J.L.7
Soliveri, J.8
Javier De La Mata, F.9
Gomez, R.10
-
162
-
-
12244292949
-
Inhibition of adhesion of type 1 fimbriated Escherichia coli to highly mannosylated ligands
-
N. Nagahori, R.T. Lee, S.I. Nishimura, D. Pagé, R. Roy, and Y.C. Lee Inhibition of adhesion of type 1 fimbriated Escherichia coli to highly mannosylated ligands ChemBioChem 3 2002 836 844
-
(2002)
ChemBioChem
, vol.3
, pp. 836-844
-
-
Nagahori, N.1
Lee, R.T.2
Nishimura, S.I.3
Pagé, D.4
Roy, R.5
Lee, Y.C.6
-
163
-
-
33750162390
-
Oligomannoside mimetics by glycosylation of 'octopus glycosides' and their investigation as inhibitors of type 1 fimbriae-mediated adhesion of Escherichia coli
-
M. Dubber, O. Sperling, and T.K. Linhorst Oligomannoside mimetics by glycosylation of 'octopus glycosides' and their investigation as inhibitors of type 1 fimbriae-mediated adhesion of Escherichia coli Organic & Biomolecular Chemistry 4 2006 3901 3912
-
(2006)
Organic & Biomolecular Chemistry
, vol.4
, pp. 3901-3912
-
-
Dubber, M.1
Sperling, O.2
Linhorst, T.K.3
-
164
-
-
79958208425
-
Combining glycomimetic and multivalent strategies toward designing potent bacterial lectin inhibitors
-
Y.M. Chabre, D. Giguère, B. Blanchard, J. Rodrigue, S. Rocheleau, M. Neault, S. Rauthu, A. Papadopoulos, A. Arnold, A. Imberty, and R. Roy Combining glycomimetic and multivalent strategies toward designing potent bacterial lectin inhibitors Chemistry: A European Journal 17 2011 6545 6562
-
(2011)
Chemistry: A European Journal
, vol.17
, pp. 6545-6562
-
-
Chabre, Y.M.1
Giguère, D.2
Blanchard, B.3
Rodrigue, J.4
Rocheleau, S.5
Neault, M.6
Rauthu, S.7
Papadopoulos, A.8
Arnold, A.9
Imberty, A.10
Roy, R.11
-
165
-
-
34447122753
-
Synthesis of glycodendrimers containing both fucoside and galactoside residues and their binding properties to PA-IL and PA-IIL lectins from pseudomonas aeruginosa
-
I. Deguise, D. Lagnoux, and R. Roy Synthesis of glycodendrimers containing both fucoside and galactoside residues and their binding properties to PA-IL and PA-IIL lectins from pseudomonas aeruginosa New Journal of Chemistry 31 2007 1321 1331
-
(2007)
New Journal of Chemistry
, vol.31
, pp. 1321-1331
-
-
Deguise, I.1
Lagnoux, D.2
Roy, R.3
-
166
-
-
57449104162
-
The First Synthesis of "majoral-type" glycodendrimers bearing covalently bound a-d-mannopyranoside residues onto a hexachlorocyclo- triphosphazene core
-
M. Touaibia, and R. Roy The First Synthesis of "Majoral-type" glycodendrimers bearing covalently bound a-d-mannopyranoside residues onto a hexachlorocyclo-triphosphazene core Journal of Organic Chemistry 73 2008 9292 9302
-
(2008)
Journal of Organic Chemistry
, vol.73
, pp. 9292-9302
-
-
Touaibia, M.1
Roy, R.2
-
167
-
-
79952443819
-
Potent antioxidant dendrimers lacking pro-oxidant activity
-
C.Y. Lee, A. Sharma, R.L. Uzarski, J.E. Cheong, H. Xu, R.A. Held, S.K. Upadhaya, and J.L. Nelson Potent antioxidant dendrimers lacking pro-oxidant activity Free Radical Biology and Medicine 50 2011 918 925
-
(2011)
Free Radical Biology and Medicine
, vol.50
, pp. 918-925
-
-
Lee, C.Y.1
Sharma, A.2
Uzarski, R.L.3
Cheong, J.E.4
Xu, H.5
Held, R.A.6
Upadhaya, S.K.7
Nelson, J.L.8
-
168
-
-
84858040498
-
Biological properties of new viologen-phosphorus dendrimers
-
K. Ciepluch, N. Katir, A. El Kadib, A. Felczak, K. Zawadzka, M. Weber, B. Klajnert, K. Lisowska, A.M. Caminade, M. Bousmina, M. Bryszewska, and J.P. Majoral Biological properties of new viologen-phosphorus dendrimers Molecular Pharmaceutics 9 2012 448 457
-
(2012)
Molecular Pharmaceutics
, vol.9
, pp. 448-457
-
-
Ciepluch, K.1
Katir, N.2
El Kadib, A.3
Felczak, A.4
Zawadzka, K.5
Weber, M.6
Klajnert, B.7
Lisowska, K.8
Caminade, A.M.9
Bousmina, M.10
Bryszewska, M.11
Majoral, J.P.12
-
169
-
-
70349295252
-
Phosphonate terminated PPH dendrimers: Influence of pendant alkyl chains on the in vitro anti-HIV-1 properties
-
G. Pérez-Anes, G. Spataro, C. Coppel, M. Moog, C. Blanzat, O. Turrin, A.M. Caminade, I. Rico-lattes, and J.P. Majoral Phosphonate terminated PPH dendrimers: influence of pendant alkyl chains on the in vitro anti-HIV-1 properties Organic & Biomolecular Chemistry 7 2009 3491 3498
-
(2009)
Organic & Biomolecular Chemistry
, vol.7
, pp. 3491-3498
-
-
Pérez-Anes, G.1
Spataro, G.2
Coppel, C.3
Moog, M.4
Blanzat, C.5
Turrin, O.6
Caminade, A.M.7
Rico-Lattes, I.8
Majoral, J.P.9
-
170
-
-
41649109652
-
Targeting the carbohydrates on HIV-1: Interaction of oligomannose dendrons with human monoclonal antibody 2G12 and DC-SIGN
-
S.K. Wang, P.H. Liang, R.D. Astronomo, T.I. Hsu, S.I. Hsieh, D.R. Burton, and C.H. Wong Targeting the carbohydrates on HIV-1: Interaction of oligomannose dendrons with human monoclonal antibody 2G12 and DC-SIGN Proceedings of the
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, pp. 3690-3695
-
-
Wang, S.K.1
Liang, P.H.2
Astronomo, R.D.3
Hsu, T.I.4
Hsieh, S.I.5
Burton, D.R.6
Wong, C.H.7
-
171
-
-
79953286869
-
N-acetylgalactosamine-functionalized dendrimers as hepatic cancer cell-targeted carriers
-
S.H. Medina, V. Tekumalla, M.V. Cheliakov, D.S. Shewach, W.D. Ensminger, and M.E.H. El-Sayed N-acetylgalactosamine-functionalized dendrimers as hepatic cancer cell-targeted carriers Biomaterials 32 2011 4118 4129
-
(2011)
Biomaterials
, vol.32
, pp. 4118-4129
-
-
Medina, S.H.1
Tekumalla, V.2
Cheliakov, M.V.3
Shewach, D.S.4
Ensminger, W.D.5
El-Sayed, M.E.H.6
-
172
-
-
77749233942
-
Systemic antiangiogenic activity of cationic poly-l-lysine dendrimer delays tumor growth
-
K.T. Al-Jamal, W.T. Al-Jamal, S. Akerman, J.E. Podesta, A. Yilmazer, J.A. Turton, A. Bianco, N. Vargesson, C. Kanthou, A.T. Florence, G.M. Tozer, and K. Kostarelos Systemic antiangiogenic activity of cationic poly-l-lysine dendrimer delays tumor growth Proceedings of the National Academy of Sciences of the United States of America 2 2010 3966 3971
-
(2010)
Proceedings of the National Academy of Sciences of the United States of America
, vol.2
, pp. 3966-3971
-
-
Al-Jamal, K.T.1
Al-Jamal, W.T.2
Akerman, S.3
Podesta, J.E.4
Yilmazer, A.5
Turton, J.A.6
Bianco, A.7
Vargesson, N.8
Kanthou, C.9
Florence, A.T.10
Tozer, G.M.11
Kostarelos, K.12
-
173
-
-
3542993234
-
Polyvalent dendrimer glucosamine conjugates prevent scar tissue formation
-
S. Shaunak, S. Thomas, E. Gianasi, A. Godwin, E. Jones, I. Teo, K. Mireskandari, P. Luther, R. Duncan, S. Patterson, P. Khaw, and S. Brocchini Polyvalent dendrimer glucosamine conjugates prevent scar tissue formation Nature Biotechnology 22 2004 977 984
-
(2004)
Nature Biotechnology
, vol.22
, pp. 977-984
-
-
Shaunak, S.1
Thomas, S.2
Gianasi, E.3
Godwin, A.4
Jones, E.5
Teo, I.6
Mireskandari, K.7
Luther, P.8
Duncan, R.9
Patterson, S.10
Khaw, P.11
Brocchini, S.12
-
174
-
-
84858060499
-
Phosphorus dendrimers affect Alzheimer's (Ab1-28) peptide and MAP-Tau protein aggregation
-
T. Wasiak, M. Ionov, K. Nieznanski, H. Nieznanska, O. Klementieva, M. Granell, J. Cladera, J.P. Majoral, A.M. Caminade, and B. Klajnert Phosphorus dendrimers affect Alzheimer's (Ab1-28) peptide and MAP-Tau protein aggregation Molecular Pharmaceutics 9 2012 458 469
-
(2012)
Molecular Pharmaceutics
, vol.9
, pp. 458-469
-
-
Wasiak, T.1
Ionov, M.2
Nieznanski, K.3
Nieznanska, H.4
Klementieva, O.5
Granell, M.6
Cladera, J.7
Majoral, J.P.8
Caminade, A.M.9
Klajnert, B.10
-
175
-
-
84860129964
-
Dendrimer-based postnatal therapy for neuroinflammation and cerebral palsy in a rabbit model
-
S. Kannan, H. Dai, R.S. Navath, B. Balahrishnan, A. Jyoti, J. Janisse, R. Romero, and R.M. Kannan Dendrimer-based postnatal therapy for neuroinflammation and cerebral palsy in a rabbit model Science Translational Medicine 4 130ra46/ 2012 1 21
-
(2012)
Science Translational Medicine
, vol.4
, Issue.130 RA46
, pp. 1-21
-
-
Kannan, S.1
Dai, H.2
Navath, R.S.3
Balahrishnan, B.4
Jyoti, A.5
Janisse, J.6
Romero, R.7
Kannan, R.M.8
-
176
-
-
34548763755
-
Strong inhibition of cholera toxin by multivalent GM1 derivatives
-
A.V. Pukin, H.M. Branderhorst, C. Sisu, C.A.G.M. Weijers, M.J. Gilbert, R.M. Liskamp, G.M. Visser, H. Zuilhof, and R.J. Pieters Strong inhibition of cholera toxin by multivalent GM1 derivatives ChemBioChem 8 2007 1500 1503
-
(2007)
ChemBioChem
, vol.8
, pp. 1500-1503
-
-
Pukin, A.V.1
Branderhorst, H.M.2
Sisu, C.3
Weijers, C.A.G.M.4
Gilbert, M.J.5
Liskamp, R.M.6
Visser, G.M.7
Zuilhof, H.8
Pieters, R.J.9
-
177
-
-
32044442705
-
Proteo-dendrimers designed for complementary recognition of cytochromec: Dendrimer architecture toward nanoscale protein complexation
-
D. Paul, H. Miyake, S. Shinoda, and H. Tsukude Proteo-dendrimers designed for complementary recognition of cytochromec: dendrimer architecture toward nanoscale protein complexation Chemistry: A European Journal 12 2006 1328 1338
-
(2006)
Chemistry: A European Journal
, vol.12
, pp. 1328-1338
-
-
Paul, D.1
Miyake, H.2
Shinoda, S.3
Tsukude, H.4
-
180
-
-
77953807630
-
Bioanalytical method development for a generation 5 polyamidoamine folic acid methotrexate conjugated nanoparticle
-
L. van Haandel, and J.F. Stoaugh Bioanalytical method development for a generation 5 polyamidoamine folic acid methotrexate conjugated nanoparticle Analytical and Bioanalytical Chemistry 397 2010 1841 1852
-
(2010)
Analytical and Bioanalytical Chemistry
, vol.397
, pp. 1841-1852
-
-
Van Haandel, L.1
Stoaugh, J.F.2
-
181
-
-
79951851197
-
Multifunctional dendrimer/combretastatin A4 inclusion complexes enable in vitro targeted cancer therapy
-
Y. Wang, R. Guo, X. Cao, M. Shen, and X. Shi Multifunctional dendrimer/combretastatin A4 inclusion complexes enable in vitro targeted cancer therapy Biomaterials 32 2011 3322 3329
-
(2011)
Biomaterials
, vol.32
, pp. 3322-3329
-
-
Wang, Y.1
Guo, R.2
Cao, X.3
Shen, M.4
Shi, X.5
-
182
-
-
33644593095
-
PAMAM dendrimer-based multifunctional conjugate for cancer therapy: Synthesis characterization and functionality
-
I.J. Majoros, A. Myc, and T. Thomas PAMAM dendrimer-based multifunctional conjugate for cancer therapy: synthesis characterization and functionality Biomacromolecules 7 2006 572 579
-
(2006)
Biomacromolecules
, vol.7
, pp. 572-579
-
-
Majoros, I.J.1
Myc, A.2
Thomas, T.3
-
183
-
-
36349032852
-
Multifunctional poly(amidoamine) dendrimer-Taxol conjugates: Synthesis characterization and stability
-
X. Bi, X. Shi, I.J. Majoros, R. Shukla, and J.R. Baker Multifunctional poly(amidoamine) dendrimer-Taxol conjugates: synthesis characterization and stability Journal of Computational and Theoretical Nanoscience 4 2007 1179 1187
-
(2007)
Journal of Computational and Theoretical Nanoscience
, vol.4
, pp. 1179-1187
-
-
Bi, X.1
Shi, X.2
Majoros, I.J.3
Shukla, R.4
Baker, J.R.5
-
184
-
-
12244271024
-
Synthesis and biological evaluation of folate receptor-targeted boronated PAMAM dendrimers as potential agents for neutron capture therapy
-
S. Shukla, G. Wu, M. Chatterjee, W. Yang, M. Sekido, L.A. Diop, R. Müller, J.J. Sudimack, R.J. Lee, R.F. Barth, and W. Tjarks Synthesis and biological evaluation of folate receptor-targeted boronated PAMAM dendrimers as potential agents for neutron capture therapy Bioconjugate Chemistry 14 2003 158 167
-
(2003)
Bioconjugate Chemistry
, vol.14
, pp. 158-167
-
-
Shukla, S.1
Wu, G.2
Chatterjee, M.3
Yang, W.4
Sekido, M.5
Diop, L.A.6
Müller, R.7
Sudimack, J.J.8
Lee, R.J.9
Barth, R.F.10
Tjarks, W.11
-
185
-
-
0027950222
-
Boronated starburst dendrimer-monoclonal antibody immunoconjugates: Evaluation as a potential delivery system for neutron capture therapy
-
R.F. Barth, D.M. Adams, A.H. Soloway, F. Alam, and M.V. Darby Boronated starburst dendrimer-monoclonal antibody immunoconjugates: evaluation as a potential delivery system for neutron capture therapy Bioconjugate Chemistry 5 1994 58 66
-
(1994)
Bioconjugate Chemistry
, vol.5
, pp. 58-66
-
-
Barth, R.F.1
Adams, D.M.2
Soloway, A.H.3
Alam, F.4
Darby, M.V.5
-
186
-
-
34547177723
-
Synthesis and characterization of PAMAM dendrimer-based multifunctional nanodevices for targeting a v b 3 integrins
-
W.G. Lesniak, M.S.T. Kariapper, and B.M. Nair Synthesis and characterization of PAMAM dendrimer-based multifunctional nanodevices for targeting a v b 3 integrins Bioconjugate Chemistry 18 2007 1148 1154
-
(2007)
Bioconjugate Chemistry
, vol.18
, pp. 1148-1154
-
-
Lesniak, W.G.1
Kariapper, M.S.T.2
Nair, B.M.3
-
187
-
-
77953295131
-
Synthesis and cytotoxic activity of G3 PAMAM-NH2 dendrimer-modified digoxin and proscillaridin A conjugates in breast cancer cells
-
K. Winnicka, K. Bielawski, and A. Bielawska Synthesis and cytotoxic activity of G3 PAMAM-NH2 dendrimer-modified digoxin and proscillaridin A conjugates in breast cancer cells Pharmacological Reports 62 2010 414 423
-
(2010)
Pharmacological Reports
, vol.62
, pp. 414-423
-
-
Winnicka, K.1
Bielawski, K.2
Bielawska, A.3
-
189
-
-
77955653059
-
Design of riboflavin-presenting PAMAM dendrimers as a new nanoplatform for cancer-targeted delivery
-
T.P. Thomas, S.K. Choi, M.H. Li, A. Kotlyar, and J.R. Baker Design of riboflavin-presenting PAMAM dendrimers as a new nanoplatform for cancer-targeted delivery Bioorganic and Medicinal Chemistry Letters 20 2010 5191 5194
-
(2010)
Bioorganic and Medicinal Chemistry Letters
, vol.20
, pp. 5191-5194
-
-
Thomas, T.P.1
Choi, S.K.2
Li, M.H.3
Kotlyar, A.4
Baker, J.R.5
-
190
-
-
79959227618
-
Efficient orthogonal bioconjugation of dendrimers for synthesis of bioactive nanoparticles
-
H. Gaertner, F. Cerini, A. Kamath, A.F. Rochat, C.A. Siegrist, L. Menin, and O. Harley Efficient orthogonal bioconjugation of dendrimers for synthesis of bioactive nanoparticles Bioconjugate Chemistry 22 2011 1103 1114
-
(2011)
Bioconjugate Chemistry
, vol.22
, pp. 1103-1114
-
-
Gaertner, H.1
Cerini, F.2
Kamath, A.3
Rochat, A.F.4
Siegrist, C.A.5
Menin, L.6
Harley, O.7
-
191
-
-
33750127627
-
Intracellular macrophage uptake of rifampicin loaded mannosylated dendrimers
-
P.V. Kumar, A. Asthana, T. Dutta, and N.K. Jain Intracellular macrophage uptake of rifampicin loaded mannosylated dendrimers Journal of Drug Targeting 14 2006 546 556
-
(2006)
Journal of Drug Targeting
, vol.14
, pp. 546-556
-
-
Kumar, P.V.1
Asthana, A.2
Dutta, T.3
Jain, N.K.4
-
192
-
-
79952189755
-
Radiosynthesis biodistribution and micro-SPECT imaging study of dendrimer-avidin conjugate
-
X. Xu, Y. Zhang, X. Wang, X. Guo, X. Zhang, Y. Qi, and Y.M. Shen Radiosynthesis biodistribution and micro-SPECT imaging study of dendrimer-avidin conjugate Bioorganic and Medicinal Chemistry 19 2011 1643 1648
-
(2011)
Bioorganic and Medicinal Chemistry
, vol.19
, pp. 1643-1648
-
-
Xu, X.1
Zhang, Y.2
Wang, X.3
Guo, X.4
Zhang, X.5
Qi, Y.6
Shen, Y.M.7
-
193
-
-
74049115136
-
Radiosynthesis and micro-SPECT imaging of 99mTc-dendrimer poly(amido)-amine folic acid conjugate
-
Y. Zhang, Y. Sun, X. Xu, H. Zhu, L. Huang, X. Zhang, Y. Qi, and Y.M. Shen Radiosynthesis and micro-SPECT imaging of 99mTc-dendrimer poly(amido)-amine folic acid conjugate Bioorganic and Medicinal Chemistry 20 2011 927 931
-
(2011)
Bioorganic and Medicinal Chemistry
, vol.20
, pp. 927-931
-
-
Zhang, Y.1
Sun, Y.2
Xu, X.3
Zhu, H.4
Huang, L.5
Zhang, X.6
Qi, Y.7
Shen, Y.M.8
-
194
-
-
77951097615
-
Synthesis biodistribution and microsingle photon emission computed tomography (SPECT) imaging study of technetium-99m labeled PEGylated dendrimer poly(amidoamine) (PAMAM)-folic acid conjugates
-
Y. Zhang, X. Sun, X. Xu, X. Zhang, H. Zhu, L. Huang, Y. Qi, and Y.M. Shen Synthesis biodistribution and microsingle photon emission computed tomography (SPECT) imaging study of technetium-99m labeled PEGylated dendrimer poly(amidoamine) (PAMAM)-folic acid conjugates Journal of Medicinal Chemistry 53 2010 3262 3272
-
(2010)
Journal of Medicinal Chemistry
, vol.53
, pp. 3262-3272
-
-
Zhang, Y.1
Sun, X.2
Xu, X.3
Zhang, X.4
Zhu, H.5
Huang, L.6
Qi, Y.7
Shen, Y.M.8
-
197
-
-
33750160205
-
The development of folate-PAMAM dendrimer conjugates for targeted delivery of anti-arthritic drugs and their pharmacokinetics and biodistribution in arthritic rats
-
D. Chandrasekar, R. Sistla, F.J. Ahmad, R.K. Khar, and P.V. Diwan The development of folate-PAMAM dendrimer conjugates for targeted delivery of anti-arthritic drugs and their pharmacokinetics and biodistribution in arthritic rats Biomaterials 28 2007 504 512
-
(2007)
Biomaterials
, vol.28
, pp. 504-512
-
-
Chandrasekar, D.1
Sistla, R.2
Ahmad, F.J.3
Khar, R.K.4
Diwan, P.V.5
-
198
-
-
78449252867
-
PEGylated poly(amidoamine) dendrimer-based dual-targeting carrier for treating brain tumors
-
H. He, Y. Li, X.R. Jia, J. Du, X. Ying, W.L. Lu, J.N. Lou, and Y. Wei PEGylated poly(amidoamine) dendrimer-based dual-targeting carrier for treating brain tumors Biomaterials 32 2011 478 487
-
(2011)
Biomaterials
, vol.32
, pp. 478-487
-
-
He, H.1
Li, Y.2
Jia, X.R.3
Du, J.4
Ying, X.5
Lu, W.L.6
Lou, J.N.7
Wei, Y.8
-
199
-
-
79959861668
-
The treatment of glioblastoma xenografts by surfactant conjugated dendritic nanoconjugates
-
V. Gajbhiye, and N.K. Jain The treatment of glioblastoma xenografts by surfactant conjugated dendritic nanoconjugates Biomaterials 32 2011 6213 6225
-
(2011)
Biomaterials
, vol.32
, pp. 6213-6225
-
-
Gajbhiye, V.1
Jain, N.K.2
-
200
-
-
56349134979
-
Surface-engineered dendrimers for dual drug delivery: A receptor up-regulation and enhanced cancer targeting strategy
-
R.K. Tekade, T. Dutta, A. Tyagi, A.C. Bharti, B.C. Das, and N.K. Jain Surface-engineered dendrimers for dual drug delivery: a receptor up-regulation and enhanced cancer targeting strategy Journal of Drug Targeting 16 2008 758 772
-
(2008)
Journal of Drug Targeting
, vol.16
, pp. 758-772
-
-
Tekade, R.K.1
Dutta, T.2
Tyagi, A.3
Bharti, A.C.4
Das, B.C.5
Jain, N.K.6
-
201
-
-
79961076051
-
Dendritic poly(ethylene glycol) bearing paclitaxel and alendronate for targeting bone neoplasms
-
C. Clementi, K. Miller, A. Mero, R. Satchi-Fainaro, and G. Pasut Dendritic poly(ethylene glycol) bearing paclitaxel and alendronate for targeting bone neoplasms Molecular Pharmaceutics 8 2011 1063 1072
-
(2011)
Molecular Pharmaceutics
, vol.8
, pp. 1063-1072
-
-
Clementi, C.1
Miller, K.2
Mero, A.3
Satchi-Fainaro, R.4
Pasut, G.5
-
202
-
-
77954579231
-
Amino acid- functionalized dendrimers with hetero-bifunctional chemoselective peripheral groups for drug delivery
-
R.S. Navath, A.R. Menjoge, B. Wang, R. Romero, S. Kannan, and R.M. Kannan Amino acid- functionalized dendrimers with hetero-bifunctional chemoselective peripheral groups for drug delivery Biomacromolecules 11 2010 1544 1563
-
(2010)
Biomacromolecules
, vol.11
, pp. 1544-1563
-
-
Navath, R.S.1
Menjoge, A.R.2
Wang, B.3
Romero, R.4
Kannan, S.5
Kannan, R.M.6
-
203
-
-
77049109479
-
Polyamidoamine (PAMAM) dendrimer conjugates of "clickable" agonists of the A3 adenosine receptor and coactivation of the P2Y14 receptor by a tethered nucleotide
-
D.K. Tosh, L.S. Yoo, M. Chinn, K. Hong, K.S.M. Kilbey, M.O. Barrett, I.P. Fricks, T.K. Harden, Z.G. Gao, and K.A. Jacobson Polyamidoamine (PAMAM) dendrimer conjugates of "clickable" agonists of the A3 adenosine receptor and coactivation of the P2Y14 receptor by a tethered nucleotide Bioconjugate Chemistry 21 2010 372 384
-
(2010)
Bioconjugate Chemistry
, vol.21
, pp. 372-384
-
-
Tosh, D.K.1
Yoo, L.S.2
Chinn, M.3
Hong, K.4
Kilbey, K.S.M.5
Barrett, M.O.6
Fricks, I.P.7
Harden, T.K.8
Gao, Z.G.9
Jacobson, K.A.10
|