Enhanced transfection of primary cortical cultures using arginine-grafted PAMAM dendrimer, PAMAM-Arg

Journal of Controlled Release

Volumn 114, Issue 1, 2006, Pages 110-117

  Kim, Jung Bin ^a   Choi, Joon Sig ^b   Nam, Kihoon ^c   Lee, Minhyung ^d   Park, Jong Sang ^c   Lee, Ja Kyeong ^a  

^a Inha University School of Medicine   (South Korea)

^b Chungnam National University   (South Korea)

^c Seoul National University   (South Korea)

^d Hanyang University   (South Korea)

Author keywords

Gene delivery; l arginine; PAMAM dendrimer; Primary cortical culture

Indexed keywords

AMINES; BIODIVERSITY; CELLS; DENDRIMERS; GENETIC ENGINEERING; POLYAMIDEIMIDES; RNA;

GENE DELIVERY; L-ARGININE; PAMAM DENDRIMERS; PRIMARY CORTICAL CULTURE;

CELL CULTURE;

DENDRIMER; GREEN FLUORESCENT PROTEIN; HIGH MOBILITY GROUP B1 PROTEIN; LIPOFECTAMINE; NAKED DNA; POLYAMIDOAMINE; POLYAMIDOAMINE ARGININE; POLYARGININE; POLYETHYLENEIMINE; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASTROCYTE; BRAIN CORTEX; CONTROLLED STUDY; CYTOTOXICITY; GENETIC TRANSFECTION; GLIA CELL; HETEROZYGOTE; MICROGLIA; NERVE CELL; NERVE CELL CULTURE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; OLIGODENDROGLIA; PRIORITY JOURNAL; RAT; REPORTER GENE;

ANIMALS; ASTROCYTES; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; DOWN-REGULATION; GENE EXPRESSION; GREEN FLUORESCENT PROTEINS; HMGB1 PROTEIN; LUCIFERASES; MICE; NEURONS; PEPTIDES; PLASMIDS; POLYAMINES; RNA INTERFERENCE; RNA, DOUBLE-STRANDED; TRANSFECTION;

EID: 33746415181     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2006.05.011     Document Type: Article

References (34)

1. Berry M., Barrett L., Seymour L., Baird A., and Logan A. Gene therapy for central nervous system repair. Curr. Opin. Mol. Ther. 3 (2001) 338-349
2. Clark K.R., Sferra T.J., Lo W., Qu G., Chen R.J., and Johnson P.R. Gene transfer into the CNS using recombinant adeno-associated virus: analysis of vector DNA forms resulting in sustained expression. J. Drug Target. 7 (1999) 269-283
3. Hughes S.M., Moussavi H., Sauter S.L., and Davidson B.L. Viral-mediated gene transfer to mouse primary neural progenitor cells. Mol. Ther. 5 (2002) 516-524
4. King L.A., Mitrophanous K.A., Clark L.A., Kim V.N., Rohll J.B., Kingsman A.J., and Colello R.J. Growth factor enhanced retroviral gene transfer to the adult central nervous system. Gene Ther. 7 (2000) 1103-1111
5. Martino G., Furlan R., Galbiati F., Poliani P.L., Bergami A., Grimaldi L.M.E., Adorini L., and Comi G. A gene therapy approach to treat demyelinating diseases using nonreplicative herpetic vectors engineered to produce cytokines. Mult. Scler. 4 (1998) 222-227
6. Kaspar B.K., Erickson D., Schaffer D., Hinh L., Gage F.H., and Peterson D.A. Targeted retrograde gene delivery for neuronal protection. Mol. Ther. 5 (2002) 50-56
7. Breakefield X.O., and DeLuca N.A. Herpes simplex virus for gene delivery to neurons. New Biol. 3 (1991) 203-218
8. Jin B.K., Belloni M., Conti B., Federoff H.J., Starr R., Son J.H., Baker H., and Joh T.H. Prolonged in vivo gene expression driven by a tyrosine hydroxylase promoter in a defective herpes simplex virus amplicon vector. Hum. Gene Ther. 7 (1996) 2015-2024
9. Jooss K., and Chirmule N. Immunity to adenovirus and adeno-associated viral vectors: implications for gene therapy. Gene Ther. 10 (2003) 955-963
10. Lawrence M.S., Foellmer H.G., Elsworth J.D., Kim J.H., Leranth C., Kozlowski D.A., Bothwell A.L., Davidson B.L., Bohn M.C., and Redmond D.E. Inflammatory responses and their impact on beta-galactosidase transgene expression following adenovirus vector delivery to the primate caudate nucleus. Gene Ther. 6 (1999) 1368-1379
11. McMenamin M.M., Byrnes A.P., Charlton H.M., Coffin R.S., Latchman D.S., and Wood M.J. A gamma34.5 mutant of herpes simplex 1 causes severe inflammation in the brain. Neuroscience 83 (1998) 1225-1237
12. Meichsner M., Doll T., Reddy D., Weisshaar B., and Matus A. The low molecular weight form of microtubule-associated protein 2 is transported into both axons and dendrites. Neuroscience 54 (1993) 873-880
13. Xia Z., Dudek H., Miranti C.K., and Greenberg M.E. Calcium influx via the NMDA receptor induces immediate early gene transcription by a MAP kinase/ERK-dependent mechanism. J. Neurosci. 16 (1996) 5425-5436
14. Tabuchi A., Sano K., Nakaoka R., Nakatani C., and Tsuda M. Inducibility of BDNF gene promoter I detected by calcium-phosphate mediated DNA transfection is confined to neuronal but not to glial cells. Biochem. Biophys. Res. Commun. 253 (1998) 818-823
15. Watanabe S.Y., Albsoul-Younes A.M., Kawano T., Itoh H., Kaziro Y., Nakajima S., and Nakajima Y. Calcium phosphate-mediated transfection of primary cultured brain neurons using GFP expression as a marker: application for single neuron electrophysiology. Neurosci. Res. 33 (1999) 71-78
16. Li H., Chan S.T.H., and Tang F. Transfection of rat brain by electroporation. J. Neurosci. Methods 75 (1997) 29-32
17. Jiao S., Cheng L., Wolff J.A., and Yang N.S. Particle bombardment-mediated gene transfer and expression in rat brain tissues. Biotechnology (NY) 11 (1993) 497-502
18. Ohki E.C., Tilkins M.L., Ciccarone V.C., and Price P.J. Improving the transfection efficiency of post-mitotic neurons. J. Neurosci. Methods 112 (2001) 95-99
19. Guerra-Crespo M., Charli J.L., Rosales-Garcia V.H., Pedraza-Alva G., and Perez-Martinez L. Polyethylenimine improves the transfection efficiency of primary cultures of post-mitotic rat fetal hypothalamic neurons. J. Neurosci. Methods 127 (2003) 179-192
20. Choi J.S., Nam K., Park J.Y., Kim J.B., Lee J.K., and Park J.S. Enhanced transfection efficiency of PAMAM dendrimer by surface modification with l-arginine. J. Control. Release 99 (2004) 445-456
21. Kim J.-B., Piao C.S., Lee K.-W., Han P.-L., Ahn J.I., Lee Y.S., and Lee J.-K. Delayed genomic responses to transient middle cerebral artery occlusion in the rat. J. Neurochem. 89 (2004) 1271-1282
22. Lee M.J., Cho S.S., You J.R., Lee Y., Kang B.D., Choi J.S., Park J.W., Suh Y.L., Kim J.A., Kim D.K., and Park J.S. Intraperitoneal gene delivery mediated by a novel cationic liposome in a peritoneal disseminated ovarian cancer model. Gene Ther. 9 (2002) 859-866
23. Yu Y.-M., Han P.-L., and Lee J.-K. JNK pathway is required for retinoic acid-induced neurite outgrowth of human neuroblastoma, SH-SY5Y. NeuroReport 14 (2003) 941-945
24. Fischer D., Li Y., Ahlemeyer B., Krieglstein J., and Kissel T. In vitro cytotoxicity testing of polycations: influence of polymer structure on cell viability and hemolysis. Biomaterials 24 (2003) 1121-1131
25. Jevprasesphant R., Penny J., Jalal R., Attwood D., McKeown N.B., and D'Emanuele A. The influence of surface modification on the cytotoxicity of PAMAM dendrimers. Int. J. Pharm. 252 (2003) 263-266
26. Sanfeliu C., Wright J.M., and Kim S.U. Neurotoxicity of isoniazid and its metabolites in cultures of mouse dorsal root ganglion neurons and hybrid neuronal cell line. Neurotoxicology 20 (1999) 935-944
27. Aoki H., Satoh M., Mitsuzuka K., Ito A., Saito S., Funato T., Endoh M., Takahashi T., and Arai Y. Inhibition of motility and invasiveness of renal cell carcinoma induced by short interfering RNA transfection of beta1, 4GalNAc transferase. FEBS Lett. 567 (2004) 203-208
28. Cho Y.Y., Bode A.M., Mizuno H., Choi B.Y., Choi H.S., and Dong Z. A novel role for mixed-lineage kinase-like mitogen-activated protein triple kinase alpha in neoplastic cell transformation and tumor development. Cancer Res. 64 (2004) 3855-3864
29. Takei Y., Kadomatsu K., Yuzawa Y., Matsuo S., and Muramatsu T. A small interfering RNA targeting vascular endothelial growth factor as cancer therapeutics. Cancer Res. 64 (2004) 3365-3370
30. Jacque J.M., Triques K., and Stevenson M. Modulation of HIV-1 replication by RNA interference. Nature 418 (2002) 435-438
31. McCaffrey A.P., Nakai H., Pandey K., Huang Z., Salazar F.H., Xu H., Wieland S.F., Marion P.L., and Kay M.A. Inhibition of hepatitis B virus in mice by RNA interference. Nat. Biotechnol. 21 (2003) 639-644
32. Landsman D., and Bustin M. A signature for the HMG-1 box DNA-binding proteins. Bioessays 15 (1993) 539-546
33. Schwarze S.R., Ho A., Vocero-Akbani A., and Dowdy S.F. In vivo protein transduction: delivery of a biologically active protein into the mouse. Science 285 (1999) 1569-1572
34. Tung C.H., and Weissleder R. Arginine containing peptides as delivery vectors. Adv. Drug Deliv. Rev. 55 (2003) 281-294