Radiosynthesis and micro-SPECT imaging of 99mTc-dendrimer poly(amido)-amine folic acid conjugate

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 3, 2010, Pages 927-931

  Zhang, Yuanqing ^a,b   Sun, Yanhong ^a   Xu, Xiaoping ^a,b   Zhu, Hua ^a,b   Huang, Liliang ^a,b   Zhang, Xuezhu ^a,b   Qi, Yujin ^a   Shen, Yu Mei ^a,c  

^a SHANGHAI INSTITUTE OF APPLIED PHYSICS   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c Shanghai Jiao Tong University   (China)

Author keywords

Dendrimer PAMAM; Folate receptor; Micro SPECT imaging; Radiolabeling

Indexed keywords

ACETYLATED DENDRIMER POLY(AMIDO)AMINE FOLIC ACID 2 (4 ISOTHIOCYANATOBENZYL) 6 METHYLDIETHYLENETRIAMINEPENTAACETIC ACID TC 99M; DENDRIMER; FOLATE RECEPTOR; TRACER; UNCLASSIFIED DRUG; FOLIC ACID; POLYAMIDOAMINE; POLYAMINE; RADIOISOTOPE; TECHNETIUM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG CLEARANCE; DRUG CONJUGATION; DRUG DISTRIBUTION; DRUG RECEPTOR BINDING; DRUG STABILITY; DRUG SYNTHESIS; DRUG UPTAKE; IN VITRO STUDY; IN VIVO STUDY; ISOTOPE LABELING; MOUSE; NONHUMAN; PLASMA CLEARANCE; RADIOACTIVITY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TUMOR MODEL; ANIMAL; BAGG ALBINO MOUSE; CHEMISTRY; COMPARATIVE STUDY; DIAGNOSTIC USE; NEOPLASM; NUDE MOUSE; PROCEDURES; SCINTISCANNING; SYNTHESIS;

ANIMALS; DENDRIMERS; FOLIC ACID; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASMS; POLYAMINES; RADIOISOTOPES; TECHNETIUM; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 74049115136     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.12.075     Document Type: Article

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