The Small Heat Shock Protein αB-Crystallin Negatively Regulates Cytochrome c- and Caspase-8-dependent Activation of Caspase-3 by Inhibiting Its Autoproteolytic Maturation

Journal of Biological Chemistry

Volumn 276, Issue 19, 2001, Pages 16059-16063

  Kamradt, Merideth C ^b   Chen, Feng ^b   Cryns, Vincent L ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; HEAT TREATMENT; PRECIPITATION (CHEMICAL);

APOPTOSIS;

ENZYMES;

ALPHAB CRYSTALLIN; CASPASE; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; DEOXYADENOSINE TRIPHOSPHATE; GAG PROTEIN; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 27; HEAT SHOCK PROTEIN 70; PROCASPASE 3; PROTEIN S 100; UNCLASSIFIED DRUG; CASP3 PROTEIN, HUMAN; CASP8 PROTEIN, HUMAN; CASP9 PROTEIN, HUMAN; CRYSTALLIN; ETOPOSIDE; RECOMBINANT PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME REGULATION; ENZYME SUBUNIT; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN PROCESSING; RECEPTOR DOWN REGULATION; BREAST TUMOR; CELL CULTURE; DRUG EFFECT; FEMALE; GENETIC TRANSFECTION; GENETICS; HEART MUSCLE; KINETICS; METABOLISM; PHYSIOLOGY;

APOPTOSIS; BREAST NEOPLASMS; CASPASE 3; CASPASE 8; CASPASE 9; CASPASES; CRYSTALLINS; CYTOCHROME C GROUP; ENZYME ACTIVATION; ETOPOSIDE; FEMALE; HEAT-SHOCK PROTEINS; HUMANS; KINETICS; MYOCARDIUM; RECOMBINANT PROTEINS; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035844174     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.C100107200     Document Type: Article

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