Two Distinct Modes of ATR Activation Orchestrated by Rad17 and Nbs1

Cell Reports

Volumn 3, Issue 5, 2013, Pages 1651-1662

  Shiotani, Bunsyo ^a,c   Nguyen, HaiDang ^a   Håkansson, Pelle ^a   Maréchal, Alexandre ^a   Tse, Alice ^a   Tahara, Hidetoshi ^c   Zou, Lee ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c HIROSHIMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ATR PROTEIN; BINDING PROTEIN; CHECKPOINT KINASE 1; DOUBLE STRANDED DNA; NIBRIN; RAD17 PROTEIN; REPLICATION FACTOR A; REPLICATION FACTOR A 32; SINGLE STRANDED DNA; UNCLASSIFIED DRUG; ATM PROTEIN; ATR PROTEIN, HUMAN; CARRIER PROTEIN; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; NBN PROTEIN, HUMAN; NUCLEAR PROTEIN; PROTEIN BINDING; PROTEIN KINASE; RAD17 PROTEIN, HUMAN; RBBP8 PROTEIN, HUMAN; RPA32 PROTEIN, HUMAN; SMALL INTERFERING RNA; TOPBP1 PROTEIN, HUMAN;

ARTICLE; CONTROLLED STUDY; DOUBLE STRANDED DNA BREAK; ENZYME ACTIVATION; IN VITRO STUDY; IN VIVO STUDY; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; ANIMAL; ANTAGONISTS AND INHIBITORS; DNA REPLICATION; GENETICS; HEK293 CELL LINE; HELA CELL LINE; HUMAN; METABOLISM; PHOSPHORYLATION; RNA INTERFERENCE; TUMOR CELL LINE;

ANIMALS; ATAXIA TELANGIECTASIA MUTATED PROTEINS; CARRIER PROTEINS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; DNA BREAKS, DOUBLE-STRANDED; DNA REPLICATION; DNA, SINGLE-STRANDED; DNA-BINDING PROTEINS; HEK293 CELLS; HELA CELLS; HUMANS; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN KINASES; REPLICATION PROTEIN A; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84878548877     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2013.04.018     Document Type: Article

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