-
1
-
-
63549113890
-
Loading clamps for DNA replication and repair
-
Bloom, L. B. (2009). Loading clamps for DNA replication and repair. DNA Repair 8, 570-578.
-
(2009)
DNA Repair
, vol.8
, pp. 570-578
-
-
Bloom, L.B.1
-
2
-
-
42949130159
-
Colocalization of sensors is sufficient to activate the DNA damage checkpoint in the absence of damage
-
Bonilla, C. Y., Melo, J. A., and Toczyski, D. P. (2008). Colocalization of sensors is sufficient to activate the DNA damage checkpoint in the absence of damage. Mol. Cell 30, 267-276.
-
(2008)
Mol. Cell
, vol.30
, pp. 267-276
-
-
Bonilla, C.Y.1
Melo, J.A.2
Toczyski, D.P.3
-
3
-
-
3042588011
-
Structural analysis of a eukaryotic sliding DNA clamp-clamp loader complex
-
Bowman, G. D., O'Donnell, M., and Kuriyan, J. (2004). Structural analysis of a eukaryotic sliding DNA clamp-clamp loader complex. Nature 429, 724-730.
-
(2004)
Nature
, vol.429
, pp. 724-730
-
-
Bowman, G.D.1
O'Donnell, M.2
Kuriyan, J.3
-
4
-
-
18244371925
-
Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint
-
Byun, T. S., Pacek, M., Yee, M. C., Walter, J. C., and Cimprich, K. A. (2005). Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint. Genes Dev. 19, 1040-1052.
-
(2005)
Genes Dev
, vol.19
, pp. 1040-1052
-
-
Byun, T.S.1
Pacek, M.2
Yee, M.C.3
Walter, J.C.4
Cimprich, K.A.5
-
5
-
-
10544250652
-
Reconstitution of human replication factor C from its five subunits in baculovirus-infected insect cells
-
Cai, J., Uhlmann, F., Gibbs, E., Flores-Rozas, H., Lee, C. G., Phillips, B., Finkelstein, J., Yao, N., O'Donnell, M., and Hurwitz, J. (1996). Reconstitution of human replication factor C from its five subunits in baculovirus-infected insect cells. Proc. Natl. Acad. Sci. USA 93, 12896-12901.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 12896-12901
-
-
Cai, J.1
Uhlmann, F.2
Gibbs, E.3
Flores-Rozas, H.4
Lee, C.G.5
Phillips, B.6
Finkelstein, J.7
Yao, N.8
O'Donnell, M.9
Hurwitz, J.10
-
6
-
-
47749141560
-
-
ATR: an essential regulator of genome integrity
-
Cimprich, K. A., and Cortez, D. (2008). ATR: an essential regulator of genome integrity. Nat. Rev. Mol. Cell Biol. 9, 616-627.
-
(2008)
Nat. Rev. Mol. Cell Biol
, vol.9
, pp. 616-627
-
-
Cimprich, K.A.1
Cortez, D.2
-
7
-
-
0035941021
-
ATR and ATRIP: Partners in checkpoint signaling
-
Cortez, D., Guntuku, S., Qin, J., and Elledge, S. J. (2001). ATR and ATRIP: partners in checkpoint signaling. Science 294, 1713-1716.
-
(2001)
Science
, vol.294
, pp. 1713-1716
-
-
Cortez, D.1
Guntuku, S.2
Qin, J.3
Elledge, S.J.4
-
8
-
-
33344464960
-
ATM regulates ATR chromatin loading in response to DNA double-strand breaks
-
Cuadrado, M., Martinez-Pastor, B., Murga, M., Toledo, L. I., Gutierrez-Martinez, P., Lopez, E., and Fernandez-Capetillo, O. (2006). ATM regulates ATR chromatin loading in response to DNA double-strand breaks. J. Exp. Med. 203, 297-303.
-
(2006)
J. Exp. Med
, vol.203
, pp. 297-303
-
-
Cuadrado, M.1
Martinez-Pastor, B.2
Murga, M.3
Toledo, L.I.4
Gutierrez-Martinez, P.5
Lopez, E.6
Fernandez-Capetillo, O.7
-
9
-
-
34250705797
-
The Rad9-Hus1-Rad1 (9-1-1) clamp activates checkpoint signaling via TopBP1
-
Delacroix, S., Wagner, J. M., Kobayashi, M., Yamamoto, K., and Karnitz, L. M. (2007). The Rad9-Hus1-Rad1 (9-1-1) clamp activates checkpoint signaling via TopBP1. Genes Dev. 21, 1472-1477.
-
(2007)
Genes Dev
, vol.21
, pp. 1472-1477
-
-
Delacroix, S.1
Wagner, J.M.2
Kobayashi, M.3
Yamamoto, K.4
Karnitz, L.M.5
-
10
-
-
0042941728
-
hRad9 rapidly binds DNA containing double-strand breaks and is required for damage-dependent topoisomerase II beta binding protein 1 focus formation
-
Greer, D. A., Besley, B. D., Kennedy, K. B., and Davey, S. (2003). hRad9 rapidly binds DNA containing double-strand breaks and is required for damage-dependent topoisomerase II beta binding protein 1 focus formation. Cancer Res. 63, 4829-4835.
-
(2003)
Cancer Res
, vol.63
, pp. 4829-4835
-
-
Greer, D.A.1
Besley, B.D.2
Kennedy, K.B.3
Davey, S.4
-
11
-
-
0034312277
-
Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts
-
Guo, Z., Kumagai, A., Wang, S. X., and Dunphy, W. G. (2000). Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts. Genes Dev. 14, 2745-2756.
-
(2000)
Genes Dev
, vol.14
, pp. 2745-2756
-
-
Guo, Z.1
Kumagai, A.2
Wang, S.X.3
Dunphy, W.G.4
-
12
-
-
21744446127
-
AAA+ proteins: Have engine, will work
-
Hanson, P. I., and Whiteheart, S. W. (2005). AAA+ proteins: have engine, will work. Nat. Rev. Mol. Cell Biol. 6, 519-529.
-
(2005)
Nat. Rev. Mol. Cell Biol
, vol.6
, pp. 519-529
-
-
Hanson, P.I.1
Whiteheart, S.W.2
-
13
-
-
0037900888
-
Xenopus Cut5 is essential for a CDK-dependent process in the initiation of DNA replication
-
Hashimoto, Y., and Takisawa, H. (2003). Xenopus Cut5 is essential for a CDK-dependent process in the initiation of DNA replication. EMBO J. 22, 2526-2535.
-
(2003)
EMBO J
, vol.22
, pp. 2526-2535
-
-
Hashimoto, Y.1
Takisawa, H.2
-
14
-
-
33747493040
-
The phosphorylated C-terminal domain of Xenopus Cut5 directly mediates ATR-dependent activation of Chk1
-
Hashimoto, Y., Tsujimura, T., Sugino, A., and Takisawa, H. (2006). The phosphorylated C-terminal domain of Xenopus Cut5 directly mediates ATR-dependent activation of Chk1. Genes Cells 11, 993-1007.
-
(2006)
Genes Cells
, vol.11
, pp. 993-1007
-
-
Hashimoto, Y.1
Tsujimura, T.2
Sugino, A.3
Takisawa, H.4
-
15
-
-
25444495672
-
Evidence that DNA damage detection machinery participates in DNA repair
-
Helt, C. E., Wang, W., Keng, P. C., and Bambara, R. A. (2005). Evidence that DNA damage detection machinery participates in DNA repair. Cell Cycle 4, 529-532.
-
(2005)
Cell Cycle
, vol.4
, pp. 529-532
-
-
Helt, C.E.1
Wang, W.2
Keng, P.C.3
Bambara, R.A.4
-
16
-
-
9244252580
-
Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks
-
Huyen, Y., Zgheib, O., Ditullio, R. A., Jr., Gorgoulis, V. G., Zacharatos, P., Petty, T. J., Sheston, E. A., Mellert, H. S., Stavridi, E. S., and Halazonetis, T. D. (2004). Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks. Nature 432, 406-411.
-
(2004)
Nature
, vol.432
, pp. 406-411
-
-
Huyen, Y.1
Zgheib, O.2
Ditullio Jr., R.A.3
Gorgoulis, V.G.4
Zacharatos, P.5
Petty, T.J.6
Sheston, E.A.7
Mellert, H.S.8
Stavridi, E.S.9
Halazonetis, T.D.10
-
17
-
-
33749033347
-
The replication clamp-loading machine at work in the three domains of life
-
Indiani, C., and O'Donnell, M. (2006). The replication clamp-loading machine at work in the three domains of life. Nat. Rev. Mol. Cell Biol. 7, 751-761.
-
(2006)
Nat. Rev. Mol. Cell Biol
, vol.7
, pp. 751-761
-
-
Indiani, C.1
O'Donnell, M.2
-
18
-
-
30344463835
-
ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks
-
Jazayeri, A., Falck, J., Lukas, C., Bartek, J., Smith, G. C., Lukas, J., and Jackson, S. P. (2006). ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks. Nat. Cell Biol. 8, 37-45.
-
(2006)
Nat. Cell Biol
, vol.8
, pp. 37-45
-
-
Jazayeri, A.1
Falck, J.2
Lukas, C.3
Bartek, J.4
Smith, G.C.5
Lukas, J.6
Jackson, S.P.7
-
19
-
-
0141632765
-
XRad17 is required for the activation of XChk1 but not XCds1 during checkpoint signaling in Xenopus
-
Jones, R. E., Chapman, J. R., Puligilla, C., Murray, J. M., Car, A. M., Ford, C. C., and Lindsay, H. D. (2003). XRad17 is required for the activation of XChk1 but not XCds1 during checkpoint signaling in Xenopus. Mol. Biol. Cell 14, 3898-3910.
-
(2003)
Mol. Biol. Cell
, vol.14
, pp. 3898-3910
-
-
Jones, R.E.1
Chapman, J.R.2
Puligilla, C.3
Murray, J.M.4
Car, A.M.5
Ford, C.C.6
Lindsay, H.D.7
-
20
-
-
0037289840
-
Repeated phosphopeptide motifs in Claspin mediate the regulated binding of Chk1
-
Kumagai, A., and Dunphy, W. G. (2003). Repeated phosphopeptide motifs in Claspin mediate the regulated binding of Chk1. Nat. Cell Biol. 5, 161-165.
-
(2003)
Nat. Cell Biol
, vol.5
, pp. 161-165
-
-
Kumagai, A.1
Dunphy, W.G.2
-
21
-
-
33745171123
-
How cells activate ATR
-
Kumagai, A., and Dunphy, W. G. (2006). How cells activate ATR. Cell Cycle 5, 1265-1268.
-
(2006)
Cell Cycle
, vol.5
, pp. 1265-1268
-
-
Kumagai, A.1
Dunphy, W.G.2
-
22
-
-
9644275421
-
Claspin and the activated form of ATR-ATRIP collaborate in the activation of Chk1
-
Kumagai, A., Kim, S. M., and Dunphy, W. G. (2004). Claspin and the activated form of ATR-ATRIP collaborate in the activation of Chk1. J. Biol. Chem. 279, 49599-49608.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 49599-49608
-
-
Kumagai, A.1
Kim, S.M.2
Dunphy, W.G.3
-
23
-
-
33644757806
-
TopBP1 activates the ATR-ATRIP complex
-
Kumagai, A., Lee, J., Yoo, H. Y., and Dunphy, W. G. (2006). TopBP1 activates the ATR-ATRIP complex. Cell 124, 943-955.
-
(2006)
Cell
, vol.124
, pp. 943-955
-
-
Kumagai, A.1
Lee, J.2
Yoo, H.Y.3
Dunphy, W.G.4
-
24
-
-
27644514672
-
Roles of replication fork-interacting and Chk1-activating domains from Claspin in a DNA replication checkpoint response
-
Lee, J., Gold, D. A., Shevchenko, A., Shevchenko, A., and Dunphy, W. G. (2005). Roles of replication fork-interacting and Chk1-activating domains from Claspin in a DNA replication checkpoint response. Mol. Biol. Cell 16, 5269-5282.
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 5269-5282
-
-
Lee, J.1
Gold, D.A.2
Shevchenko, A.3
Shevchenko, A.4
Dunphy, W.G.5
-
25
-
-
0037291130
-
Claspin, a Chk1-regulatory protein, monitors DNA replication on chromatin independently of RPA, ATR, and Rad17
-
Lee, J., Kumagai, A., and Dunphy, W. G. (2003). Claspin, a Chk1-regulatory protein, monitors DNA replication on chromatin independently of RPA, ATR, and Rad17. Mol. Cell 11, 329-340.
-
(2003)
Mol. Cell
, vol.11
, pp. 329-340
-
-
Lee, J.1
Kumagai, A.2
Dunphy, W.G.3
-
26
-
-
34948889415
-
The Rad9-Hus1-Rad1 checkpoint clamp regulates interaction of TopBP1 with ATR
-
Lee, J., Kumagai, A., and Dunphy, W. G. (2007). The Rad9-Hus1-Rad1 checkpoint clamp regulates interaction of TopBP1 with ATR. J. Biol. Chem. 282, 28036-28044.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 28036-28044
-
-
Lee, J.1
Kumagai, A.2
Dunphy, W.G.3
-
27
-
-
36949026694
-
Activation and regulation of ATM kinase activity in response to DNA double-strand breaks
-
Lee, J. H., and Paull, T. T. (2007). Activation and regulation of ATM kinase activity in response to DNA double-strand breaks. Oncogene 26, 7741-7748.
-
(2007)
Oncogene
, vol.26
, pp. 7741-7748
-
-
Lee, J.H.1
Paull, T.T.2
-
28
-
-
3042597013
-
Absence of BLM leads to accumulation of chromosomal DNA breaks during both unperturbed and disrupted S phases
-
Li, W., Kim, S. M., Lee, J., and Dunphy, W. G. (2004). Absence of BLM leads to accumulation of chromosomal DNA breaks during both unperturbed and disrupted S phases. J. Cell Biol. 165, 801-812.
-
(2004)
J. Cell Biol
, vol.165
, pp. 801-812
-
-
Li, W.1
Kim, S.M.2
Lee, J.3
Dunphy, W.G.4
-
29
-
-
12344254254
-
Characterization of a novel ATR-dependent, Chk1-independent, intra-S-phase checkpoint that suppresses initiation of replication in Xenopus
-
Luciani, M. G., Oehlmann, M., and Blow, J. J. (2004). Characterization of a novel ATR-dependent, Chk1-independent, intra-S-phase checkpoint that suppresses initiation of replication in Xenopus. J. Cell Sci. 117, 6019-6030.
-
(2004)
J. Cell Sci
, vol.117
, pp. 6019-6030
-
-
Luciani, M.G.1
Oehlmann, M.2
Blow, J.J.3
-
30
-
-
2442646313
-
Requirement for ATP by the DNA damage checkpoint clamp loader
-
Majka, J., Chung, B. Y., and Burgers, P. M. (2004). Requirement for ATP by the DNA damage checkpoint clamp loader. J. Biol. Chem. 279, 20921-20926.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 20921-20926
-
-
Majka, J.1
Chung, B.Y.2
Burgers, P.M.3
-
31
-
-
33845607102
-
The checkpoint clamp activates Mec1 kinase during initiation of the DNA damage checkpoint
-
Majka, J., Niedziela-Majka, A., and Burgers, P. M. (2006). The checkpoint clamp activates Mec1 kinase during initiation of the DNA damage checkpoint. Mol. Cell 24, 891-901.
-
(2006)
Mol. Cell
, vol.24
, pp. 891-901
-
-
Majka, J.1
Niedziela-Majka, A.2
Burgers, P.M.3
-
32
-
-
0242456024
-
BRCT domain-containing protein TopBP1 functions in DNA replication and damage response
-
Makiniemi, M., et al. (2001). BRCT domain-containing protein TopBP1 functions in DNA replication and damage response. J. Biol. Chem. 276, 30399-30406.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 30399-30406
-
-
Makiniemi, M.1
-
33
-
-
0034028908
-
Dpb11 controls the association between DNA polymerases alpha and epsilon and the autonomously replicating sequence region of budding yeast
-
Masumoto, H., Sugino, A., and Araki, H. (2000). Dpb11 controls the association between DNA polymerases alpha and epsilon and the autonomously replicating sequence region of budding yeast. Mol. Cell. Biol. 20, 2809-2817.
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 2809-2817
-
-
Masumoto, H.1
Sugino, A.2
Araki, H.3
-
34
-
-
44849093460
-
TopBP1 activates ATR through ATRIP and a PIKK regulatory domain
-
Mordes, D. A., Glick, G. G., Zhao, R., and Cortez, D. (2008). TopBP1 activates ATR through ATRIP and a PIKK regulatory domain. Genes Dev. 22, 1478-1489.
-
(2008)
Genes Dev
, vol.22
, pp. 1478-1489
-
-
Mordes, D.A.1
Glick, G.G.2
Zhao, R.3
Cortez, D.4
-
35
-
-
0026266161
-
Cell cycle extracts
-
Murray, A. W. (1991). Cell cycle extracts. Methods Cell Biol. 36, 581-605.
-
(1991)
Methods Cell Biol
, vol.36
, pp. 581-605
-
-
Murray, A.W.1
-
36
-
-
68249113358
-
A tale of two tails: Activation of DNA damage checkpoint kinase Mec1/ATR by the 9-1-1 clamp and by Dpb11/TopBP1
-
Navadgi-Patil, V.M., and Burgers, P.M. (2009). A tale of two tails: activation of DNA damage checkpoint kinase Mec1/ATR by the 9-1-1 clamp and by Dpb11/TopBP1. DNA Repair. 8, 996-1003.
-
(2009)
DNA Repair
, vol.8
, pp. 996-1003
-
-
Navadgi-Patil, V.M.1
Burgers, P.M.2
-
37
-
-
3242887431
-
Dial 9-1-1 for DNA damage: The Rad9-Hus1-Rad1 (9-1-1) clamp complex
-
Parrilla-Castellar, E. R., Arlander, S. J., and Karnitz, L. (2004). Dial 9-1-1 for DNA damage: the Rad9-Hus1-Rad1 (9-1-1) clamp complex. DNA Repair 3, 1009-1014.
-
(2004)
DNA Repair
, vol.3
, pp. 1009-1014
-
-
Parrilla-Castellar, E.R.1
Arlander, S.J.2
Karnitz, L.3
-
38
-
-
0242413125
-
Cut5 is required for the binding of Atr and DNA polymerase alpha to genotoxin-damaged chromatin
-
Parrilla-Castellar, E. R., and Karnitz, L. M. (2003). Cut5 is required for the binding of Atr and DNA polymerase alpha to genotoxin-damaged chromatin. J. Biol. Chem. 278, 45507-45511.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 45507-45511
-
-
Parrilla-Castellar, E.R.1
Karnitz, L.M.2
-
39
-
-
24944575222
-
Signal transduction: How rad53 kinase is activated
-
Pellicioli, A., and Foiani, M. (2005). Signal transduction: how rad53 kinase is activated. Curr. Biol. 15, R769-771.
-
(2005)
Curr. Biol
, vol.15
-
-
Pellicioli, A.1
Foiani, M.2
-
40
-
-
44349145455
-
The MRN complex
-
Rupnik, A., Grenon, M., and Lowndes, N. (2008). The MRN complex. Curr. Biol. 18, R455-457.
-
(2008)
Curr. Biol
, vol.18
-
-
Rupnik, A.1
Grenon, M.2
Lowndes, N.3
-
41
-
-
3943107573
-
Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints
-
Sancar, A., Lindsey-Boltz, L. A., Unsal-Kacmaz, K., and Linn, S. (2004). Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints. Annu. Rev. Biochem. 73, 39-85.
-
(2004)
Annu. Rev. Biochem
, vol.73
, pp. 39-85
-
-
Sancar, A.1
Lindsey-Boltz, L.A.2
Unsal-Kacmaz, K.3
Linn, S.4
-
42
-
-
0036281710
-
Rad9 phosphorylation sites couple Rad53 to the Saccharomyces cerevisiae DNA damage checkpoint
-
Schwartz, M. F., Duong, J. K., Sun, Z., Morrow, J. S., Pradhan, D., and Stern, D. F. (2002). Rad9 phosphorylation sites couple Rad53 to the Saccharomyces cerevisiae DNA damage checkpoint. Mol. Cell 9, 1055-1065.
-
(2002)
Mol. Cell
, vol.9
, pp. 1055-1065
-
-
Schwartz, M.F.1
Duong, J.K.2
Sun, Z.3
Morrow, J.S.4
Pradhan, D.5
Stern, D.F.6
-
43
-
-
3242670803
-
ATR and ATM regulate the timing of DNA replication origin firing
-
Shechter, D., Costanzo, V., and Gautier, J. (2004). ATR and ATM regulate the timing of DNA replication origin firing. Nat. Cell Biol. 6, 648-655.
-
(2004)
Nat. Cell Biol
, vol.6
, pp. 648-655
-
-
Shechter, D.1
Costanzo, V.2
Gautier, J.3
-
44
-
-
33745823159
-
The ATM-mediated DNA-damage response: Taking shape
-
Shiloh, Y. (2006). The ATM-mediated DNA-damage response: taking shape. Trends Biochem. Sci. 31, 402-410.
-
(2006)
Trends Biochem. Sci
, vol.31
, pp. 402-410
-
-
Shiloh, Y.1
-
45
-
-
61649093808
-
Single-stranded DNA orchestrates an ATM-to-ATR switch at DNA breaks
-
Shiotani, B., and Zou, L. (2009). Single-stranded DNA orchestrates an ATM-to-ATR switch at DNA breaks. Mol. Cell 33, 547-558.
-
(2009)
Mol. Cell
, vol.33
, pp. 547-558
-
-
Shiotani, B.1
Zou, L.2
-
46
-
-
0037698170
-
A role for the phosphorylation of hRad9 in checkpoint signaling
-
St Onge, R. P., Besley, B. D., Pelley, J. L., and Davey, S. (2003). A role for the phosphorylation of hRad9 in checkpoint signaling. J. Biol. Chem. 278, 26620-26628.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 26620-26628
-
-
St Onge, R.P.1
Besley, B.D.2
Pelley, J.L.3
Davey, S.4
-
47
-
-
0037468192
-
MDC1 is a mediator of the mammalian DNA damage checkpoint
-
Stewart, G. S., Wang, B., Bignell, C. R., Taylor, A. M., and Elledge, S. J. (2003). MDC1 is a mediator of the mammalian DNA damage checkpoint. Nature 421, 961-966.
-
(2003)
Nature
, vol.421
, pp. 961-966
-
-
Stewart, G.S.1
Wang, B.2
Bignell, C.R.3
Taylor, A.M.4
Elledge, S.J.5
-
48
-
-
20244388673
-
Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage
-
Syljuasen, R. G., Sorensen, C. S., Hansen, L. T., Fugger, K., Lundin, C., Johansson, F., Helleday, T., Sehested, M., Lukas, J., and Bartek, J. (2005). Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage. Mol. Cell. Biol. 25, 3553-3562.
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 3553-3562
-
-
Syljuasen, R.G.1
Sorensen, C.S.2
Hansen, L.T.3
Fugger, K.4
Lundin, C.5
Johansson, F.6
Helleday, T.7
Sehested, M.8
Lukas, J.9
Bartek, J.10
-
49
-
-
0037175392
-
The Xenopus Xmus101 protein is required for the recruitment of Cdc45 to origins of DNA replication
-
Van Hatten, R. A., Tutter, A. V., Holway, A. H., Khederian, A. M., Walter, J. C., and Michael, W. M. (2002). The Xenopus Xmus101 protein is required for the recruitment of Cdc45 to origins of DNA replication. J. Cell Biol. 159, 541-547.
-
(2002)
J. Cell Biol
, vol.159
, pp. 541-547
-
-
Van Hatten, R.A.1
Tutter, A.V.2
Holway, A.H.3
Khederian, A.M.4
Walter, J.C.5
Michael, W.M.6
-
50
-
-
33746408535
-
Rad17 phosphorylation is required for claspin recruitment and Chk1 activation in response to replication stress
-
Wang, X., Zou, L., Lu, T., Bao, S., Hurov, K. E., Hittelman, W. N., Elledge, S. J., and Li, L. (2006). Rad17 phosphorylation is required for claspin recruitment and Chk1 activation in response to replication stress. Mol. Cell 23, 331-341.
-
(2006)
Mol. Cell
, vol.23
, pp. 331-341
-
-
Wang, X.1
Zou, L.2
Lu, T.3
Bao, S.4
Hurov, K.E.5
Hittelman, W.N.6
Elledge, S.J.7
Li, L.8
-
51
-
-
0034655991
-
BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures
-
Wang, Y., Cortez, D., Yazdi, P., Neff, N., Elledge, S. J., and Qin, J. (2000). BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures. Genes Dev. 14, 927-939.
-
(2000)
Genes Dev
, vol.14
, pp. 927-939
-
-
Wang, Y.1
Cortez, D.2
Yazdi, P.3
Neff, N.4
Elledge, S.J.5
Qin, J.6
-
52
-
-
0035930537
-
Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress
-
Ward, I. M., and Chen, J. (2001). Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress. J. Biol. Chem. 276, 47759-47762.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 47759-47762
-
-
Ward, I.M.1
Chen, J.2
-
53
-
-
34948899943
-
Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template
-
Williams, R. S., Williams, J. S., and Tainer, J. A. (2007). Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template. Biochem. Cell Biol. 85, 509-520.
-
(2007)
Biochem. Cell Biol
, vol.85
, pp. 509-520
-
-
Williams, R.S.1
Williams, J.S.2
Tainer, J.A.3
-
54
-
-
56449084007
-
NFBD1/MDC1, 53BP1 and BRCA1 have both redundant and unique roles in the ATM pathway
-
Wilson, K. A., and Stern, D. F. (2008). NFBD1/MDC1, 53BP1 and BRCA1 have both redundant and unique roles in the ATM pathway. Cell Cycle 7, 3584-3594.
-
(2008)
Cell Cycle
, vol.7
, pp. 3584-3594
-
-
Wilson, K.A.1
Stern, D.F.2
-
55
-
-
33646119403
-
Direct requirement for Xmus101 in ATR-mediated phosphorylation of Claspin bound Chk1 during checkpoint signaling
-
Yan, S., Lindsay, H. D., and Michael, W. M. (2006). Direct requirement for Xmus101 in ATR-mediated phosphorylation of Claspin bound Chk1 during checkpoint signaling. J. Cell Biol. 173, 181-186.
-
(2006)
J. Cell Biol
, vol.173
, pp. 181-186
-
-
Yan, S.1
Lindsay, H.D.2
Michael, W.M.3
-
56
-
-
64049105391
-
TopBP1 and DNA polymerase-alpha directly recruit the 9-1-1 complex to stalled DNA replication forks
-
Yan, S., and Michael, W. M. (2009). TopBP1 and DNA polymerase-alpha directly recruit the 9-1-1 complex to stalled DNA replication forks. J. Cell Biol. 184, 793-804.
-
(2009)
J. Cell Biol
, vol.184
, pp. 793-804
-
-
Yan, S.1
Michael, W.M.2
-
57
-
-
34547115962
-
Ataxia-telangiectasia mutated (ATM)-dependent activation of ATR occurs through phosphorylation of TopBP1 by ATM
-
Yoo, H. Y., Kumagai, A., Shevchenko, A., Shevchenko, A., and Dunphy, W. G. (2007). Ataxia-telangiectasia mutated (ATM)-dependent activation of ATR occurs through phosphorylation of TopBP1 by ATM. J. Biol. Chem. 282, 17501-17506.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 17501-17506
-
-
Yoo, H.Y.1
Kumagai, A.2
Shevchenko, A.3
Shevchenko, A.4
Dunphy, W.G.5
-
58
-
-
65649085176
-
The Mre11-Rad50-Nbs1 complex mediates activation of TopBP1 by ATM
-
Yoo, H. Y., Kumagai, A., Shevchenko, A., Shevchenko, A., and Dunphy, W. G. (2009). The Mre11-Rad50-Nbs1 complex mediates activation of TopBP1 by ATM. Mol. Biol. Cell 20, 2351-2360.
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 2351-2360
-
-
Yoo, H.Y.1
Kumagai, A.2
Shevchenko, A.3
Shevchenko, A.4
Dunphy, W.G.5
-
59
-
-
0037567268
-
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
-
Zou, L., and Elledge, S. J. (2003). Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science 300, 1542-1548.
-
(2003)
Science
, vol.300
, pp. 1542-1548
-
-
Zou, L.1
Elledge, S.J.2
|