Selective killing of ATM- or p53-deficient cancer cells through inhibition of ATR

Nature Chemical Biology

Volumn 7, Issue 7, 2011, Pages 428-430

  Reaper, Philip M ^a   Griffiths, Matthew R ^a   Long, Joanna M ^a   Charrier, Jean Damien ^a   MacCormick, Somhairle ^a   Charlton, Peter A ^a   Golec, Julian M C ^a   Pollard, John R ^a  

^a VERTEX PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; ATR PROTEIN; CISPLATIN; PROTEIN P53; PROTEIN SERINE THREONINE KINASE;

ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER INHIBITION; CANCER PATIENT; CELL CYCLE S PHASE; CELL DEATH; CROSS REACTION; DNA DAMAGE; GENOTOXICITY; HUMAN; IONIZING RADIATION; OUTCOME ASSESSMENT; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS INHIBITION; SIGNAL TRANSDUCTION; SURVIVAL;

EID: 79959376888     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.573     Document Type: Article

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