DNA repair factor MRE11/RAD50 cleaves 3′-phosphotyrosyl bonds and resects DNA to repair damage caused by topoisomerase 1 poisons

Journal of Biological Chemistry

Volumn 286, Issue 52, 2011, Pages 44945-44951

  Sacho, Elizabeth J ^a   Maizels, Nancy ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; CAMPTOTHECINS; CLEAVAGE ACTIVITIES; DNA COMPLEX; DNA REPAIR; DOUBLE-STRAND BREAKS; REPAIR DAMAGE; TOPOISOMERASES;

REPAIR; SYNTHESIS (CHEMICAL);

DNA;

ADENOSINE TRIPHOSPHATE; CAMPTOTHECIN; DNA TOPOISOMERASE; DOUBLE STRANDED DNA; MRE11 PROTEIN; RAD50 PROTEIN; TYROSINE;

ARTICLE; CHEMICAL BOND; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DNA STRAND BREAKAGE; DNA STRUCTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN FUNCTION; PYROCOCCUS FURIOSUS;

ARCHAEAL PROTEINS; CAMPTOTHECIN; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; DNA TOPOISOMERASES, TYPE I; DNA-BINDING PROTEINS; PYROCOCCUS FURIOSUS; TOPOISOMERASE I INHIBITORS;

EID: 84455192646     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.299347     Document Type: Article

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