-
1
-
-
0035449355
-
Cell cycle checkpoint signaling through the ATM and ATR kinases
-
Abraham, R. T. 2001. Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes Dev. 15:2177-2196.
-
(2001)
Genes Dev.
, vol.15
, pp. 2177-2196
-
-
Abraham, R.T.1
-
2
-
-
0035735472
-
Mrc1 transduces signals of DNA replication stress to activate Rad53
-
Alcasabas, A. A., A. J. Osborn, J. Bachant, F. Hu, P. J. Werler, K. Bousset, K. Furuya, J. F. Diffley, A. M. Carr, and S. J. Elledge. 2001. Mrc1 transduces signals of DNA replication stress to activate Rad53. Nat. Cell Biol. 3:958-965.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 958-965
-
-
Alcasabas, A.A.1
Osborn, A.J.2
Bachant, J.3
Hu, F.4
Werler, P.J.5
Bousset, K.6
Furuya, K.7
Diffley, J.F.8
Carr, A.M.9
Elledge, S.J.10
-
3
-
-
24744448894
-
ATRIP oligomerization is required for ATR-dependent checkpoint signaling
-
Ball, H. L., and D. Cortez. 2005. ATRIP oligomerization is required for ATR-dependent checkpoint signaling. J. Biol. Chem. 280:31390-31396.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 31390-31396
-
-
Ball, H.L.1
Cortez, D.2
-
4
-
-
18244385718
-
ATRIP binding to replication protein A-single-stranded DNA promotes ATR-ATRIP localization but is dispensable for Chk1 phosphorylation
-
Ball, H. L., J. S. Myers, and D. Cortez. 2005. ATRIP binding to replication protein A-single-stranded DNA promotes ATR-ATRIP localization but is dispensable for Chk1 phosphorylation. Mol. Biol. Cell 16:2372-2381.
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 2372-2381
-
-
Ball, H.L.1
Myers, J.S.2
Cortez, D.3
-
5
-
-
0038418869
-
Chk1 and Chk2 kinases in checkpoint control and cancer
-
Bartek, J., and J. Lukas. 2003. Chk1 and Chk2 kinases in checkpoint control and cancer. Cancer Cell 3:421-429.
-
(2003)
Cancer Cell
, vol.3
, pp. 421-429
-
-
Bartek, J.1
Lukas, J.2
-
6
-
-
33646117239
-
Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks
-
Bekker-Jensen, S., C. Lukas, R. Kitagawa, F. Melander, M. B. Kastan, J. Bartek, and J. Lukas. 2006. Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks. J. Cell Biol. 173:195-206.
-
(2006)
J. Cell Biol.
, vol.173
, pp. 195-206
-
-
Bekker-Jensen, S.1
Lukas, C.2
Kitagawa, R.3
Melander, F.4
Kastan, M.B.5
Bartek, J.6
Lukas, J.7
-
7
-
-
22944462083
-
Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1
-
Bekker-Jensen, S., C. Lukas, F. Melander, J. Bartek, and J. Lukas. 2005. Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1. J. Cell Biol. 170:201-211.
-
(2005)
J. Cell Biol.
, vol.170
, pp. 201-211
-
-
Bekker-Jensen, S.1
Lukas, C.2
Melander, F.3
Bartek, J.4
Lukas, J.5
-
8
-
-
0242497228
-
Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage
-
Busino, L., M. Donzelli, M. Chiesa, D. Guardavaccaro, D. Ganoth, N. V. Dorrello, A. Hershko, M. Pagano, and G. F. Draetta. 2003. Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage. Nature 426:87-91.
-
(2003)
Nature
, vol.426
, pp. 87-91
-
-
Busino, L.1
Donzelli, M.2
Chiesa, M.3
Guardavaccaro, D.4
Ganoth, D.5
Dorrello, N.V.6
Hershko, A.7
Pagano, M.8
Draetta, G.F.9
-
9
-
-
3242878502
-
Claspin, a regulator of Chk1 in DNA replication stress pathway
-
Chini, C. C., and J. Chen. 2004. Claspin, a regulator of Chk1 in DNA replication stress pathway. DNA Repair 3:1033-1037.
-
(2004)
DNA Repair
, vol.3
, pp. 1033-1037
-
-
Chini, C.C.1
Chen, J.2
-
10
-
-
0043032435
-
Human claspin is required for replication checkpoint control
-
Chini, C. C., and J. Chen. 2003. Human claspin is required for replication checkpoint control. J. Biol. Chem. 278:30057-30062.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 30057-30062
-
-
Chini, C.C.1
Chen, J.2
-
11
-
-
20544478438
-
DNA-dependent phosphorylation of Chk1 and Claspin in a human cell-free system
-
Clarke, C. A., and P. R. Clarke. 2005. DNA-dependent phosphorylation of Chk1 and Claspin in a human cell-free system. Biochem. J. 388:705-712.
-
(2005)
Biochem. J.
, vol.388
, pp. 705-712
-
-
Clarke, C.A.1
Clarke, P.R.2
-
12
-
-
0034177408
-
Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice
-
de Klein, A., M. Muijtjens, R. van Os, Y. Verhoeven, B. Smit, A. M. Carr, A. R. Lehmann, and J. H. Hoeijmakers. 2000. Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice. Curr. Biol. 10:479-482.
-
(2000)
Curr. Biol.
, vol.10
, pp. 479-482
-
-
De Klein, A.1
Muijtjens, M.2
Van Os, R.3
Verhoeven, Y.4
Smit, B.5
Carr, A.M.6
Lehmann, A.R.7
Hoeijmakers, J.H.8
-
13
-
-
0036510055
-
The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways
-
Falck, J., J. H. Petrini, B. R. Williams, J. Lukas, and J. Bartek. 2002. The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways. Nat. Genet. 30:290-294.
-
(2002)
Nat. Genet.
, vol.30
, pp. 290-294
-
-
Falck, J.1
Petrini, J.H.2
Williams, B.R.3
Lukas, J.4
Bartek, J.5
-
14
-
-
27544460716
-
Identification and functional analysis of TopBP1 and its homologs
-
Garcia, V., K. Furuya, and A. M. Carr. 2005. Identification and functional analysis of TopBP1 and its homologs. DNA Repair 4:1227-1239.
-
(2005)
DNA Repair
, vol.4
, pp. 1227-1239
-
-
Garcia, V.1
Furuya, K.2
Carr, A.M.3
-
15
-
-
30344463835
-
ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks
-
Jazayeri, A., J. Falck, C. Lukas, J. Bartek, G. C. Smith, J. Lukas, and S. P. Jackson. 2006. ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks. Nat. Cell Biol. 8:37-45.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 37-45
-
-
Jazayeri, A.1
Falck, J.2
Lukas, C.3
Bartek, J.4
Smith, G.C.5
Lukas, J.6
Jackson, S.P.7
-
16
-
-
0344443718
-
Phosphorylated claspin interacts with a phosphate-binding site in the kinase domain of Chk1 during ATR-mediated activation
-
Jeong, S. Y., A. Kumagai, J. Lee, and W. G. Dunphy. 2003. Phosphorylated claspin interacts with a phosphate-binding site in the kinase domain of Chk1 during ATR-mediated activation. J. Biol. Chem. 278:46782-46788.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 46782-46788
-
-
Jeong, S.Y.1
Kumagai, A.2
Lee, J.3
Dunphy, W.G.4
-
17
-
-
0042242580
-
Regulation of Chk1 includes chromatin association and 14-3-3 binding following phosphorylation on Ser-345
-
Jiang, K., E. Pereira, M. Maxfield, B. Russell, D. M. Goudelock, and Y. Sanchez. 2003. Regulation of Chk1 includes chromatin association and 14-3-3 binding following phosphorylation on Ser-345. J. Biol. Chem. 278:25207-25217.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 25207-25217
-
-
Jiang, K.1
Pereira, E.2
Maxfield, M.3
Russell, B.4
Goudelock, D.M.5
Sanchez, Y.6
-
18
-
-
0347361537
-
SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase
-
Jin, J., T. Shirogane, L. Xu, G. Nalepa, J. Qin, S. J. Elledge, and J. W. Harper. 2003. SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase. Genes Dev. 17:3062-3074.
-
(2003)
Genes Dev.
, vol.17
, pp. 3062-3074
-
-
Jin, J.1
Shirogane, T.2
Xu, L.3
Nalepa, G.4
Qin, J.5
Elledge, S.J.6
Harper, J.W.7
-
19
-
-
28544450740
-
Human TopBP1 ensures genome integrity during normal S phase
-
Kim, J. E., S. A. McAvoy, D. I. Smith, and J. Chen. 2005. Human TopBP1 ensures genome integrity during normal S phase. Mol. Cell. Biol. 25:10907-10915.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 10907-10915
-
-
Kim, J.E.1
McAvoy, S.A.2
Smith, D.I.3
Chen, J.4
-
20
-
-
0033634679
-
Claspin, a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts
-
Kumagai, A., and W. G. Dunphy. 2000. Claspin, a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts. Mol. Cell 6:839-849.
-
(2000)
Mol. Cell
, vol.6
, pp. 839-849
-
-
Kumagai, A.1
Dunphy, W.G.2
-
21
-
-
0037289840
-
Repeated phosphopeptide motifs in Claspin mediate the regulated binding of Chk1
-
Kumagai, A., and W. G. Dunphy. 2003. Repeated phosphopeptide motifs in Claspin mediate the regulated binding of Chk1. Nat. Cell Biol. 5:161-165.
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 161-165
-
-
Kumagai, A.1
Dunphy, W.G.2
-
22
-
-
9644275421
-
Claspin and the activated form of ATR-ATRIP collaborate in the activation of Chk1
-
Kumagai, A., S. M. Kim, and W. G. Dunphy. 2004. Claspin and the activated form of ATR-ATRIP collaborate in the activation of Chk1. J. Biol. Chem. 279:49599-49608.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 49599-49608
-
-
Kumagai, A.1
Kim, S.M.2
Dunphy, W.G.3
-
23
-
-
33644757806
-
TopBP1 activates the ATR-ATRIP complex
-
Kumagai, A., J. Lee, H. Y. Yoo, and W. G. Dunphy. 2006. TopBP1 activates the ATR-ATRIP complex. Cell 124:943-955.
-
(2006)
Cell
, vol.124
, pp. 943-955
-
-
Kumagai, A.1
Lee, J.2
Yoo, H.Y.3
Dunphy, W.G.4
-
24
-
-
0345352653
-
Regulation of E2F1 by BRCT domain-containing protein TopBP1
-
Liu, K., F. T. Lin, J. M. Ruppert, and W. C. Lin. 2003. Regulation of E2F1 by BRCT domain-containing protein TopBP1. Mol. Cell. Biol. 23:3287-3304.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 3287-3304
-
-
Liu, K.1
Lin, F.T.2
Ruppert, J.M.3
Lin, W.C.4
-
25
-
-
1842831271
-
TopBP1 recruits Brg1/Brm to repress E2F1-induced apoptosis, a novel pRb-independent and E2F1-specific control for cell survival
-
Liu, K., Y. Luo, F. T. Lin, and W. C. Lin. 2004. TopBP1 recruits Brg1/Brm to repress E2F1-induced apoptosis, a novel pRb-independent and E2F1-specific control for cell survival. Genes Dev. 18:673-686.
-
(2004)
Genes Dev.
, vol.18
, pp. 673-686
-
-
Liu, K.1
Luo, Y.2
Lin, F.T.3
Lin, W.C.4
-
26
-
-
0037341599
-
Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage
-
Lukas, C., J. Falck, J. Bartkova, J. Bartek, and J. Lukas. 2003. Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage. Nat. Cell Biol. 5:255-260.
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 255-260
-
-
Lukas, C.1
Falck, J.2
Bartkova, J.3
Bartek, J.4
Lukas, J.5
-
27
-
-
3342915628
-
Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention
-
Lukas, C., F. Melander, M. Stucki, J. Falck, S. Bekker-Jensen, M. Goldberg, Y. Lerenthal, S. P. Jackson, J. Bartek, and J. Lukas. 2004. Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention. EMBO J. 23:2674-2683.
-
(2004)
EMBO J.
, vol.23
, pp. 2674-2683
-
-
Lukas, C.1
Melander, F.2
Stucki, M.3
Falck, J.4
Bekker-Jensen, S.5
Goldberg, M.6
Lerenthal, Y.7
Jackson, S.P.8
Bartek, J.9
Lukas, J.10
-
28
-
-
33745331961
-
Phosphorylation of Xenopus Rad1 and Hus1 defines a readout for ATR activation that is independent of Claspin and the Rad9 carboxy terminus
-
Lupardus, P. J., and K. A. Cimprich. 2006. Phosphorylation of Xenopus Rad1 and Hus1 defines a readout for ATR activation that is independent of Claspin and the Rad9 carboxy terminus. Mol. Biol. Cell 17:1559-1569.
-
(2006)
Mol. Biol. Cell
, vol.17
, pp. 1559-1569
-
-
Lupardus, P.J.1
Cimprich, K.A.2
-
29
-
-
0034717309
-
Rapid destruction of human Cdc25A in response to DNA damage
-
Mailand, N., J. Falck, C. Lukas, R. G. Syljuasen, M. Welcker, J. Bartek, and J. Lukas. 2000. Rapid destruction of human Cdc25A in response to DNA damage. Science 288:1425-1429.
-
(2000)
Science
, vol.288
, pp. 1425-1429
-
-
Mailand, N.1
Falck, J.2
Lukas, C.3
Syljuasen, R.G.4
Welcker, M.5
Bartek, J.6
Lukas, J.7
-
30
-
-
0242456024
-
BRCT domain-containing protein TopBP1 functions in DNA replication and damage response
-
Makiniemi, M., T. Hillukkala, J. Tuusa, K. Reini, M. Vaara, D. Huang, H. Pospiech, I. Majuri, T. Westerling, T. P. Makela, and J. E. Syvaoja. 2001. BRCT domain-containing protein TopBP1 functions in DNA replication and damage response. J. Biol. Chem. 276:30399-30406.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 30399-30406
-
-
Makiniemi, M.1
Hillukkala, T.2
Tuusa, J.3
Reini, K.4
Vaara, M.5
Huang, D.6
Pospiech, H.7
Majuri, I.8
Westerling, T.9
Makela, T.P.10
Syvaoja, J.E.11
-
31
-
-
0242413125
-
Cut5 is required for the binding of Atr and DNA polymerase alpha to genotoxin-damaged chromatin
-
Parrilla-Castellar, E. R., and L. M. Karnitz. 2003. Cut5 is required for the binding of Atr and DNA polymerase alpha to genotoxin-damaged chromatin. J. Biol. Chem. 278:45507-45511.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 45507-45511
-
-
Parrilla-Castellar, E.R.1
Karnitz, L.M.2
-
32
-
-
0030867582
-
Conservation of the Chk1 checkpoint pathway in mammals: Linkage of DNA damage to Cdk regulation through Cdc25
-
Sanchez, Y., C. Wong, R. S. Thoma, R. Richman, Z. Wu, H. Piwnica-Worms, and S. J. Elledge. 1997. Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25. Science 277:1497-1501.
-
(1997)
Science
, vol.277
, pp. 1497-1501
-
-
Sanchez, Y.1
Wong, C.2
Thoma, R.S.3
Richman, R.4
Wu, Z.5
Piwnica-Worms, H.6
Elledge, S.J.7
-
33
-
-
0037365789
-
ATM and related protein kinases: Safeguarding genome integrity
-
Shiloh, Y. 2003. ATM and related protein kinases: safeguarding genome integrity. Nat. Rev. Cancer 3:155-168.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 155-168
-
-
Shiloh, Y.1
-
34
-
-
30944435598
-
Rapid PIKK-dependent release of Chk1 from chromatin promotes the DNA-damage checkpoint response
-
Smits, V. A., P. M. Reaper, and S. P. Jackson. 2006. Rapid PIKK-dependent release of Chk1 from chromatin promotes the DNA-damage checkpoint response. Curr. Biol. 16:150-159.
-
(2006)
Curr. Biol.
, vol.16
, pp. 150-159
-
-
Smits, V.A.1
Reaper, P.M.2
Jackson, S.P.3
-
35
-
-
0012966157
-
Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25 a
-
Sorensen, C. S., R. G. Syljuasen, J. Falck, T. Schroeder, L. Ronnstrand, K. K. Khanna, B. B. Zhou, J. Bartek, and J. Lukas. 2003. Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25 A. Cancer Cell 3:247-258.
-
(2003)
Cancer Cell
, vol.3
, pp. 247-258
-
-
Sorensen, C.S.1
Syljuasen, R.G.2
Falck, J.3
Schroeder, T.4
Ronnstrand, L.5
Khanna, K.K.6
Zhou, B.B.7
Bartek, J.8
Lukas, J.9
-
36
-
-
0036929125
-
DNA polymerase clamp shows little turnover at established replication sites but sequential de novo assembly at adjacent origin clusters
-
Sporbert, A., A. Gahl, R. Ankerhold, H. Leonhardt, and M. C. Cardoso. 2002. DNA polymerase clamp shows little turnover at established replication sites but sequential de novo assembly at adjacent origin clusters. Mol. Cell 10:1355-1365.
-
(2002)
Mol. Cell
, vol.10
, pp. 1355-1365
-
-
Sporbert, A.1
Gahl, A.2
Ankerhold, R.3
Leonhardt, H.4
Cardoso, M.C.5
-
37
-
-
0037468192
-
MDC1 is a mediator of the mammalian DNA damage checkpoint
-
Stewart, G. S., B. Wang, C. R. Bignell, A. M. Taylor, and S. J. Elledge. 2003. MDC1 is a mediator of the mammalian DNA damage checkpoint. Nature 421:961-966.
-
(2003)
Nature
, vol.421
, pp. 961-966
-
-
Stewart, G.S.1
Wang, B.2
Bignell, C.R.3
Taylor, A.M.4
Elledge, S.J.5
-
38
-
-
1942538492
-
ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation
-
Stiff, T., M. O'Driscoll, N. Rief, K. Iwabuchi, M. Lobrich, and P. A. Jeggo. 2004. ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation. Cancer Res. 64:2390-2396.
-
(2004)
Cancer Res.
, vol.64
, pp. 2390-2396
-
-
Stiff, T.1
O'Driscoll, M.2
Rief, N.3
Iwabuchi, K.4
Lobrich, M.5
Jeggo, P.A.6
-
39
-
-
3242885156
-
MDC1/NFBD1: A key regulator of the DNA damage response in higher eukaryotes
-
Stucki, M., and S. P. Jackson. 2004. MDC1/NFBD1: a key regulator of the DNA damage response in higher eukaryotes. DNA Repair 3:953-957.
-
(2004)
DNA Repair
, vol.3
, pp. 953-957
-
-
Stucki, M.1
Jackson, S.P.2
-
40
-
-
20244388673
-
Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage
-
Syljuasen, R. G., C. S. Sorensen, L. T. Hansen, K. Fugger, C. Lundin, F. Johansson, T. Helleday, M. Sehested, J. Lukas, and J. Bartek. 2005. Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage. Mol. Cell. Biol. 25:3553-3562.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 3553-3562
-
-
Syljuasen, R.G.1
Sorensen, C.S.2
Hansen, L.T.3
Fugger, K.4
Lundin, C.5
Johansson, F.6
Helleday, T.7
Sehested, M.8
Lukas, J.9
Bartek, J.10
-
41
-
-
10844237358
-
Inhibition of Chk1 by CEP-3891 accelerates mitotic nuclear fragmentation in response to ionizing radiation
-
Syljuasen, R. G., C. S. Sorensen, J. Nylandsted, C. Lukas, J. Lukas, and J. Bartek. 2004. Inhibition of Chk1 by CEP-3891 accelerates mitotic nuclear fragmentation in response to ionizing radiation. Cancer Res. 64:9035-9040.
-
(2004)
Cancer Res.
, vol.64
, pp. 9035-9040
-
-
Syljuasen, R.G.1
Sorensen, C.S.2
Nylandsted, J.3
Lukas, C.4
Lukas, J.5
Bartek, J.6
-
42
-
-
0034659341
-
-/- mice
-
-/- mice. Genes Dev. 14:1439-1447.
-
(2000)
Genes Dev.
, vol.14
, pp. 1439-1447
-
-
Takai, H.1
Tominaga, K.2
Motoyama, N.3
Minamishima, Y.A.4
Nagahama, H.5
Tsukiyama, T.6
Ikeda, K.7
Nakayama, K.8
Nakanishi, M.9
-
43
-
-
0035736486
-
Mrc1 channels the DNA replication arrest signal to checkpoint kinase Cds1
-
Tanaka, K., and P. Russell. 2001. Mrc1 channels the DNA replication arrest signal to checkpoint kinase Cds1. Nat. Cell Biol. 3:966-972.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 966-972
-
-
Tanaka, K.1
Russell, P.2
-
44
-
-
0035930537
-
Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress
-
Ward, I. M., and J. Chen. 2001. Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress. J. Biol. Chem. 276:47759-47762.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 47759-47762
-
-
Ward, I.M.1
Chen, J.2
-
45
-
-
4544269236
-
Microcephalin is a DNA damage response protein involved in regulation of CHK1 and BRCA1
-
Xu, X., J. Lee, and D. F. Stern. 2004. Microcephalin is a DNA damage response protein involved in regulation of CHK1 and BRCA1. J. Biol. Chem. 279:34091-34094.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 34091-34094
-
-
Xu, X.1
Lee, J.2
Stern, D.F.3
-
46
-
-
0031574247
-
A DNA-topoisomerase-11-binding protein with eight repeating regions similar to DNA-repair enzymes and to a cell-cycle regulator
-
Yamane, K., M. Kawabata, and T. Tsuruo. 1997. A DNA-topoisomerase-11- binding protein with eight repeating regions similar to DNA-repair enzymes and to a cell-cycle regulator. Eur. J. Biochem. 250:794-799.
-
(1997)
Eur. J. Biochem.
, vol.250
, pp. 794-799
-
-
Yamane, K.1
Kawabata, M.2
Tsuruo, T.3
-
47
-
-
0036134979
-
A DNA damage-regulated BRCT-containing protein, TopBP1, is required for cell survival
-
Yamane, K., X. Wu, and J. Chen. 2002. A DNA damage-regulated BRCT-containing protein, TopBP1, is required for cell survival. Mol. Cell. Biol. 22:555-566.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 555-566
-
-
Yamane, K.1
Wu, X.2
Chen, J.3
-
48
-
-
33646119403
-
Direct requirement for Xmus101 in ATR-mediated phosphorylation of Claspin bound Chk1 during checkpoint signaling
-
Yan, S., H. D. Lindsay, and W. M. Michael. 2006. Direct requirement for Xmus101 in ATR-mediated phosphorylation of Claspin bound Chk1 during checkpoint signaling. J. Cell Biol. 173:181-186.
-
(2006)
J. Cell Biol.
, vol.173
, pp. 181-186
-
-
Yan, S.1
Lindsay, H.D.2
Michael, W.M.3
-
49
-
-
0034967556
-
ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1
-
Zhao, H., and H. Piwnica-Worms. 2001. ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1. Mol. Cell. Biol. 21:4129-4139.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 4129-4139
-
-
Zhao, H.1
Piwnica-Worms, H.2
-
50
-
-
0034707047
-
The DNA damage response: Putting checkpoints in perspective
-
Zhou, B. B., and S. J. Elledge. 2000. The DNA damage response: putting checkpoints in perspective. Nature 408:433-439.
-
(2000)
Nature
, vol.408
, pp. 433-439
-
-
Zhou, B.B.1
Elledge, S.J.2
-
51
-
-
0037567268
-
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
-
Zou, L., and S. J. Elledge. 2003. Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science 300:1542-1548.
-
(2003)
Science
, vol.300
, pp. 1542-1548
-
-
Zou, L.1
Elledge, S.J.2
|