메뉴 건너뛰기




Volumn 31, Issue 6, 2010, Pages 994-1002

The role of RPA2 phosphorylation in homologous recombination in response to replication arrest

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYUREA; RAD51 PROTEIN; REPLICATION FACTOR A; REPLICATION FACTOR A 2; SINGLE STRANDED DNA; UNCLASSIFIED DRUG; RAD51 PROTEIN, HUMAN; RPA2 PROTEIN, HUMAN;

EID: 77953932126     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgq035     Document Type: Article
Times cited : (74)

References (65)
  • 1
    • 29244437908 scopus 로고    scopus 로고
    • The role of double-strand break repair-insights from human genetics
    • O'Driscoll,M. et al. (2006) The role of double-strand break repair-insights from human genetics. Nat. Rev. Genet., 7, 45-54.
    • (2006) Nat. Rev. Genet. , vol.7 , pp. 45-54
    • O'Driscoll, M.1
  • 2
    • 1642443168 scopus 로고    scopus 로고
    • Mechanisms of replication fork restart in Escherichia coli
    • Marians,K.J. (2004) Mechanisms of replication fork restart in Escherichia coli. Philos. trans. R. Soc. Lond., 359, 71-77.
    • (2004) Philos. trans. R. Soc. Lond. , vol.359 , pp. 71-77
    • Marians, K.J.1
  • 3
    • 0037349263 scopus 로고    scopus 로고
    • Connecting replication and recombination
    • Lovett,S.T. (2003) Connecting replication and recombination. Mol. Cell, 11, 554-556.
    • (2003) Mol. Cell , vol.11 , pp. 554-556
    • Lovett, S.T.1
  • 4
    • 33845330910 scopus 로고    scopus 로고
    • Replisome assembly and the direct restart of stalled replication forks
    • Heller,R.C. et al. (2006) Replisome assembly and the direct restart of stalled replication forks. Nat. Rev., 7, 932-943.
    • (2006) Nat. Rev. , vol.7 , pp. 932-943
    • Heller, R.C.1
  • 5
    • 33845604556 scopus 로고    scopus 로고
    • DNA double-strand break repair: all's well that ends well
    • Wyman,C. et al. (2006) DNA double-strand break repair: all's well that ends well. Annu. Rev. Genet., 40, 363-383.
    • (2006) Annu. Rev. Genet. , vol.40 , pp. 363-383
    • Wyman, C.1
  • 6
    • 34249945536 scopus 로고    scopus 로고
    • DNA double-strand break repair: from mechanistic understanding to cancer treatment
    • Helleday,T. et al. (2007) DNA double-strand break repair: from mechanistic understanding to cancer treatment. DNA Repair (Amst.), 6, 923-935.
    • (2007) DNA Repair (Amst.) , vol.6 , pp. 923-935
    • Helleday, T.1
  • 7
    • 0742305344 scopus 로고    scopus 로고
    • RNA interference inhibition of Mus81 reduces mitotic recombination in human cells
    • Blais,V. et al. (2004) RNA interference inhibition of Mus81 reduces mitotic recombination in human cells. Mol. Biol. Cell, 15, 552-562.
    • (2004) Mol. Biol. Cell , vol.15 , pp. 552-562
    • Blais, V.1
  • 8
    • 34249942213 scopus 로고    scopus 로고
    • Exploring the roles of Mus81-Eme1/Mms4 at perturbed replication forks
    • Osman,F. et al. (2007) Exploring the roles of Mus81-Eme1/Mms4 at perturbed replication forks. DNA Repair (Amst.), 6, 1004-1017.
    • (2007) DNA Repair (Amst.) , vol.6 , pp. 1004-1017
    • Osman, F.1
  • 9
    • 33750206776 scopus 로고    scopus 로고
    • The structure-specific endonuclease Mus81-Eme1 promotes conversion of interstrand DNA crosslinks into double-strands breaks
    • Hanada,K. et al. (2006) The structure-specific endonuclease Mus81-Eme1 promotes conversion of interstrand DNA crosslinks into double-strands breaks. EMBO J., 25, 4921-4932.
    • (2006) EMBO J. , vol.25 , pp. 4921-4932
    • Hanada, K.1
  • 10
    • 1942532917 scopus 로고    scopus 로고
    • Requirement for RecFOR-mediated recombination in priA mutant
    • Grompone,G. et al. (2004) Requirement for RecFOR-mediated recombination in priA mutant. Mol. Microbiol., 52, 551-562.
    • (2004) Mol. Microbiol. , vol.52 , pp. 551-562
    • Grompone, G.1
  • 11
    • 0023707742 scopus 로고
    • Replication of simian virus 40 DNA after UV irradiation: evidence of growing fork blockage and single-stranded gaps in daughter strands
    • Mezzina,M. et al. (1988) Replication of simian virus 40 DNA after UV irradiation: evidence of growing fork blockage and single-stranded gaps in daughter strands. J. Virol., 62, 4249-4258.
    • (1988) J. Virol. , vol.62 , pp. 4249-4258
    • Mezzina, M.1
  • 12
    • 0029586324 scopus 로고
    • Differential replication of a single, UV-induced lesion in the leading or lagging strand by a human cell extract: fork uncoupling or gap formation
    • Svoboda,D.L. et al. (1995) Differential replication of a single, UV-induced lesion in the leading or lagging strand by a human cell extract: fork uncoupling or gap formation. Proc. Natl Acad. Sci. USA, 92, 11975-11979.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 11975-11979
    • Svoboda, D.L.1
  • 13
    • 0030925436 scopus 로고    scopus 로고
    • Replication fork bypass of a pyrimidine dimer blocking leading strand DNA synthesis
    • Cordeiro-Stone,M. et al. (1997) Replication fork bypass of a pyrimidine dimer blocking leading strand DNA synthesis. J. Biol. Chem., 272, 13945-13954.
    • (1997) J. Biol. Chem. , vol.272 , pp. 13945-13954
    • Cordeiro-Stone, M.1
  • 14
    • 0033603630 scopus 로고    scopus 로고
    • Analysis of DNA replication forks encountering a pyrimidine dimer in the template to the leading strand
    • Cordeiro-Stone,M. et al. (1999) Analysis of DNA replication forks encountering a pyrimidine dimer in the template to the leading strand. J. Mol. Biol., 289, 1207-1218.
    • (1999) J. Mol. Biol. , vol.289 , pp. 1207-1218
    • Cordeiro-Stone, M.1
  • 15
    • 0032497368 scopus 로고    scopus 로고
    • The 32and 14-kilodalton subunits of replication protein A are responsible for species-specific interactions with single-stranded DNA
    • Sibenaller,Z.A. et al. (1998) The 32and 14-kilodalton subunits of replication protein A are responsible for species-specific interactions with single-stranded DNA. Biochemistry, 37, 12496-12506.
    • (1998) Biochemistry , vol.37 , pp. 12496-12506
    • Sibenaller, Z.A.1
  • 16
    • 0033575671 scopus 로고    scopus 로고
    • The crystal structure of the complex of replication protein A subunits RPA32 and RPA14 reveals a mechanism for singlestranded DNA binding
    • Bochkarev,A. et al. (1999) The crystal structure of the complex of replication protein A subunits RPA32 and RPA14 reveals a mechanism for singlestranded DNA binding. EMBO J., 18, 4498-4504.
    • (1999) EMBO J. , vol.18 , pp. 4498-4504
    • Bochkarev, A.1
  • 17
    • 3442896884 scopus 로고    scopus 로고
    • Replication protein A phosphorylation and the cellular response to DNA damage
    • Binz,S.K. et al. (2004) Replication protein A phosphorylation and the cellular response to DNA damage. DNA Repair (Amst.), 3, 1015-1024.
    • (2004) DNA Repair (Amst.) , vol.3 , pp. 1015-1024
    • Binz, S.K.1
  • 18
    • 0030908093 scopus 로고    scopus 로고
    • Replication protein A: a heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism
    • Wold,M.S. (1997) Replication protein A: a heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism. Annu. Rev. Biochem., 66, 61-92.
    • (1997) Annu. Rev. Biochem. , vol.66 , pp. 61-92
    • Wold, M.S.1
  • 19
    • 0037567268 scopus 로고    scopus 로고
    • Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
    • Zou,L. et al. (2003) Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science, 300, 1542-1548.
    • (2003) Science , vol.300 , pp. 1542-1548
    • Zou, L.1
  • 20
    • 31444452984 scopus 로고    scopus 로고
    • ATRIP associates with replication protein A-coated ssDNA through multiple interactions
    • Namiki,Y. et al. (2006) ATRIP associates with replication protein A-coated ssDNA through multiple interactions. Proc. Natl Acad. Sci. USA, 103, 580-585.
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 580-585
    • Namiki, Y.1
  • 21
    • 0030766963 scopus 로고    scopus 로고
    • The human Rad51 protein: polarity of strand transfer and stimulation by hRP-A
    • Baumann,P. et al. (1997) The human Rad51 protein: polarity of strand transfer and stimulation by hRP-A. EMBO J., 16, 5198-5206.
    • (1997) EMBO J. , vol.16 , pp. 5198-5206
    • Baumann, P.1
  • 22
    • 0037199924 scopus 로고    scopus 로고
    • Rad52 protein associates with replication protein A (RPA)-single-stranded DNA to accelerate Rad51-mediated displacement of RPA and presynaptic complex formation
    • Sugiyama,T. et al. (2002) Rad52 protein associates with replication protein A (RPA)-single-stranded DNA to accelerate Rad51-mediated displacement of RPA and presynaptic complex formation. J. Biol. Chem., 277, 31663-31672.
    • (2002) J. Biol. Chem. , vol.277 , pp. 31663-31672
    • Sugiyama, T.1
  • 23
    • 33749134033 scopus 로고    scopus 로고
    • A dynamic model for replication protein A (RPA) function in DNA processing pathways
    • Fanning,E. et al. (2006) A dynamic model for replication protein A (RPA) function in DNA processing pathways. Nucleic Acids Res., 34, 4126-4137.
    • (2006) Nucleic Acids Res. , vol.34 , pp. 4126-4137
    • Fanning, E.1
  • 24
    • 0030924695 scopus 로고    scopus 로고
    • Mapping of amino acid residues in the p34 subunit of human single-stranded DNA-binding protein phosphorylated by DNAdependent protein kinase and Cdc2 kinase in vitro
    • Niu,H. et al. (1997) Mapping of amino acid residues in the p34 subunit of human single-stranded DNA-binding protein phosphorylated by DNAdependent protein kinase and Cdc2 kinase in vitro. J. Biol. Chem., 272, 12634-12641.
    • (1997) J. Biol. Chem. , vol.272 , pp. 12634-12641
    • Niu, H.1
  • 25
    • 0030810633 scopus 로고    scopus 로고
    • Sites of UV-induced phosphorylation of the p34 subunit of replication protein A from HeLa cells
    • Zernik-Kobak,M. et al. (1997) Sites of UV-induced phosphorylation of the p34 subunit of replication protein A from HeLa cells. J. Biol. Chem., 272, 23896-23904.
    • (1997) J. Biol. Chem. , vol.272 , pp. 23896-23904
    • Zernik-Kobak, M.1
  • 26
    • 20444375871 scopus 로고    scopus 로고
    • DNA damage induced hyperphosphorylation of replication protein A. 1. Identification of novel sites of phosphorylation in response to DNA damage.
    • Nuss,J.E. et al. (2005) DNA damage induced hyperphosphorylation of replication protein A. 1. Identification of novel sites of phosphorylation in response to DNA damage. Biochemistry, 44, 8428-8437.
    • (2005) Biochemistry , vol.44 , pp. 8428-8437
    • Nuss, J.E.1
  • 27
    • 37249080597 scopus 로고    scopus 로고
    • Sequential and synergistic modification of human RPA stimulates chromosomal DNA repair
    • Anantha,R.W. et al. (2007) Sequential and synergistic modification of human RPA stimulates chromosomal DNA repair. J. Biol. Chem., 282, 35910-35923.
    • (2007) J. Biol. Chem. , vol.282 , pp. 35910-35923
    • Anantha, R.W.1
  • 28
    • 0242417571 scopus 로고    scopus 로고
    • RPA phosphorylation in mitosis alters DNA binding and protein-protein interactions
    • Oakley,G.G. et al. (2003) RPA phosphorylation in mitosis alters DNA binding and protein-protein interactions. Biochemistry, 42, 3255-3264.
    • (2003) Biochemistry , vol.42 , pp. 3255-3264
    • Oakley, G.G.1
  • 29
    • 25444485251 scopus 로고    scopus 로고
    • Modulation of replication protein A function by its hyperphosphorylation-induced conformational change involving DNA binding domain B
    • Liu,Y. et al. (2005) Modulation of replication protein A function by its hyperphosphorylation-induced conformational change involving DNA binding domain B. J. Biol. Chem., 280, 32775-32783.
    • (2005) J. Biol. Chem. , vol.280 , pp. 32775-32783
    • Liu, Y.1
  • 30
    • 51349140504 scopus 로고    scopus 로고
    • RPA phosphorylation facilitates mitotic exit in response to mitotic DNA damage
    • Anantha,R.W. et al. (2008) RPA phosphorylation facilitates mitotic exit in response to mitotic DNA damage. Proc. Natl Acad. Sci. USA, 105, 12903-12908.
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 12903-12908
    • Anantha, R.W.1
  • 31
    • 70350540470 scopus 로고    scopus 로고
    • Protein phosphatase 2A-dependent dephosphorylation of replication protein A is required for the repair of DNA breaks induced by replication stress
    • Feng,J. et al. (2009) Protein phosphatase 2A-dependent dephosphorylation of replication protein A is required for the repair of DNA breaks induced by replication stress. Mol. Cell. Biol., 29, 5696-5709.
    • (2009) Mol. Cell. Biol. , vol.29 , pp. 5696-5709
    • Feng, J.1
  • 32
    • 27744588177 scopus 로고    scopus 로고
    • Preferential localization of hyperphosphorylated replication protein A to double-strand break repair and checkpoint complexes upon DNA damage
    • Wu,X. et al. (2005) Preferential localization of hyperphosphorylated replication protein A to double-strand break repair and checkpoint complexes upon DNA damage. Biochem. J., 391, 473-480.
    • (2005) Biochem. J. , vol.391 , pp. 473-480
    • Wu, X.1
  • 33
    • 33845991538 scopus 로고    scopus 로고
    • RPA2 is a direct downstream target for ATR to regulate the S-phase checkpoint
    • Olson,E. et al. (2006) RPA2 is a direct downstream target for ATR to regulate the S-phase checkpoint. J. Biol. Chem., 281, 39517-39533.
    • (2006) J. Biol. Chem. , vol.281 , pp. 39517-39533
    • Olson, E.1
  • 34
    • 1342325347 scopus 로고    scopus 로고
    • Replication protein A (RPA) phosphorylation prevents RPA association with replication centers
    • Vassin,V.M. et al. (2004) Replication protein A (RPA) phosphorylation prevents RPA association with replication centers. Mol. Cell. Biol., 24, 1930-1943.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 1930-1943
    • Vassin, V.M.1
  • 35
    • 0033514993 scopus 로고    scopus 로고
    • Nuclear foci of mammalian recombination proteins are located at single-stranded DNA regions formed after DNA damage
    • Raderschall,E. et al. (1999) Nuclear foci of mammalian recombination proteins are located at single-stranded DNA regions formed after DNA damage. Proc. Natl Acad. Sci. USA, 96, 1921-1926.
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 1921-1926
    • Raderschall, E.1
  • 36
    • 0035898405 scopus 로고    scopus 로고
    • Characterization of homologous recombination induced by replication inhibition in mammalian cells
    • Saintigny,Y. et al. (2001) Characterization of homologous recombination induced by replication inhibition in mammalian cells. EMBO J., 20, 3861-3870.
    • (2001) EMBO J. , vol.20 , pp. 3861-3870
    • Saintigny, Y.1
  • 37
    • 0036316015 scopus 로고    scopus 로고
    • Different roles for nonhomologous end joining and homologous recombination following replication arrest in mammalian cells
    • Lundin,C. et al. (2002) Different roles for nonhomologous end joining and homologous recombination following replication arrest in mammalian cells. Mol. Cell. Biol., 22, 5869-5878.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 5869-5878
    • Lundin, C.1
  • 38
    • 0025270234 scopus 로고
    • Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cells measured using the "comet" assay
    • Olive,P.L. et al. (1990) Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cells measured using the "comet" assay. Radiat. Res., 122, 86-94.
    • (1990) Radiat. Res. , vol.122 , pp. 86-94
    • Olive, P.L.1
  • 39
    • 0027428513 scopus 로고
    • The ionizing radiation-induced replication protein A phosphorylation response differs between ataxia telangiectasia and normal human cells
    • Liu,V.F. et al. (1993) The ionizing radiation-induced replication protein A phosphorylation response differs between ataxia telangiectasia and normal human cells. Mol. Cell. Biol., 13, 7222-7231.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 7222-7231
    • Liu, V.F.1
  • 40
    • 0029143646 scopus 로고
    • scid cells are deficient in Ku and replication protein A phosphorylation by the DNA-dependent protein kinase
    • Boubnov,N.V. et al. (1995) scid cells are deficient in Ku and replication protein A phosphorylation by the DNA-dependent protein kinase. Mol. Cell. Biol., 15, 5700-5706.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 5700-5706
    • Boubnov, N.V.1
  • 42
    • 70349301958 scopus 로고    scopus 로고
    • Ionizing radiation-dependent and independent phosphorylation of the 32-kDa subunit of replication protein A during mitosis
    • Stephan,H. et al. (2009) Ionizing radiation-dependent and independent phosphorylation of the 32-kDa subunit of replication protein A during mitosis. Nucleic Acids Res., 37, 6028-6041.
    • (2009) Nucleic Acids Res. , vol.37 , pp. 6028-6041
    • Stephan, H.1
  • 43
    • 33744947315 scopus 로고    scopus 로고
    • BRCA1 promotes induction of ssDNA by ionizing radiation
    • Schlegel,B.P. et al. (2006) BRCA1 promotes induction of ssDNA by ionizing radiation. Cancer Res., 66, 5181-5189.
    • (2006) Cancer Res. , vol.66 , pp. 5181-5189
    • Schlegel, B.P.1
  • 44
    • 36549060102 scopus 로고    scopus 로고
    • Human CtIP promotes DNA end resection
    • Sartori,A.A. et al. (2007) Human CtIP promotes DNA end resection. Nature, 450, 509-514.
    • (2007) Nature , vol.450 , pp. 509-514
    • Sartori, A.A.1
  • 45
    • 0028245269 scopus 로고
    • Recombinant replication protein A: expression, complex formation, and functional characterization
    • Henricksen,L.A. et al. (1994) Recombinant replication protein A: expression, complex formation, and functional characterization. J. Biol. Chem., 269, 11121-11132.
    • (1994) J. Biol. Chem. , vol.269 , pp. 11121-11132
    • Henricksen, L.A.1
  • 46
    • 0026563099 scopus 로고
    • Cell cycle regulated phosphorylation of RPA-32 occurs within the replication initiation complex
    • Fotedar,R. et al. (1992) Cell cycle regulated phosphorylation of RPA-32 occurs within the replication initiation complex. EMBO J., 11, 2177-2187.
    • (1992) EMBO J. , vol.11 , pp. 2177-2187
    • Fotedar, R.1
  • 47
    • 34548186415 scopus 로고    scopus 로고
    • Pol eta is required for DNA replication during nucleotide deprivation by hydroxyurea
    • de Feraudy,S. et al. (2007) Pol eta is required for DNA replication during nucleotide deprivation by hydroxyurea. Oncogene, 26, 5713-5721.
    • (2007) Oncogene , vol.26 , pp. 5713-5721
    • de Feraudy, S.1
  • 48
    • 0034600975 scopus 로고    scopus 로고
    • Sister chromatid gene conversion is a prominent double-strand break repair pathway in mammalian cells
    • Johnson,R.D. et al. (2000) Sister chromatid gene conversion is a prominent double-strand break repair pathway in mammalian cells. EMBO J., 19, 3398-3407.
    • (2000) EMBO J. , vol.19 , pp. 3398-3407
    • Johnson, R.D.1
  • 49
    • 0032518657 scopus 로고    scopus 로고
    • Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death
    • Sonoda,E. et al. (1998) Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death. EMBO J., 17, 598-608.
    • (1998) EMBO J. , vol.17 , pp. 598-608
    • Sonoda, E.1
  • 50
    • 23344444636 scopus 로고    scopus 로고
    • Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks
    • Saleh-Gohari,N. et al. (2005) Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks. Mol. Cell. Biol., 25, 7158-7169.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 7158-7169
    • Saleh-Gohari, N.1
  • 51
    • 0033569684 scopus 로고    scopus 로고
    • XRCC3 promotes homology-directed repair of DNA damage in mammalian cells
    • Pierce,A.J. et al. (1999) XRCC3 promotes homology-directed repair of DNA damage in mammalian cells. Genes Dev., 13, 2633-2638.
    • (1999) Genes Dev. , vol.13 , pp. 2633-2638
    • Pierce, A.J.1
  • 52
    • 44949096478 scopus 로고    scopus 로고
    • A mutant allele of MRE11 found in mismatch repairdeficient tumor cells suppresses the cellular response to DNA replication fork stress in a dominant negative manner
    • Wen,Q. et al. (2008) A mutant allele of MRE11 found in mismatch repairdeficient tumor cells suppresses the cellular response to DNA replication fork stress in a dominant negative manner. Mol. Biol. Cell, 19, 1693-1705.
    • (2008) Mol. Biol. Cell , vol.19 , pp. 1693-1705
    • Wen, Q.1
  • 53
    • 9744284973 scopus 로고    scopus 로고
    • ATM is required for the cellular response to thymidine induced replication fork stress
    • Bolderson,E. et al. (2004) ATM is required for the cellular response to thymidine induced replication fork stress. Hum. Mol. Genet., 13, 2937-2945.
    • (2004) Hum. Mol. Genet. , vol.13 , pp. 2937-2945
    • Bolderson, E.1
  • 54
    • 13944266820 scopus 로고    scopus 로고
    • The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair
    • Sorensen,C.S. et al. (2005) The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair. Nat. Cell Biol., 7, 195-201.
    • (2005) Nat. Cell Biol. , vol.7 , pp. 195-201
    • Sorensen, C.S.1
  • 55
    • 27144503470 scopus 로고    scopus 로고
    • MDC1 interacts with Rad51 and facilitates homologous recombination
    • Zhang,J. et al. (2005) MDC1 interacts with Rad51 and facilitates homologous recombination. Nat. Struct. Mol. Biol., 12, 902-909.
    • (2005) Nat. Struct. Mol. Biol. , vol.12 , pp. 902-909
    • Zhang, J.1
  • 56
    • 29244489543 scopus 로고    scopus 로고
    • Fanconi anemia (cross)linked to DNA repair
    • Niedernhofer,L.J. et al. (2005) Fanconi anemia (cross)linked to DNA repair. Cell, 123, 1191-1198.
    • (2005) Cell , vol.123 , pp. 1191-1198
    • Niedernhofer, L.J.1
  • 57
    • 1942502234 scopus 로고    scopus 로고
    • Tracing the network connecting BRCA and Fanconi anaemia proteins
    • Venkitaraman,A.R. (2004) Tracing the network connecting BRCA and Fanconi anaemia proteins. Nat. Rev. Cancer, 4, 266-276.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 266-276
    • Venkitaraman, A.R.1
  • 58
    • 67349167663 scopus 로고    scopus 로고
    • The MRX complex stabilizes the replisome independently of the S phase checkpoint during replication stress
    • Tittel-Elmer,M. et al. (2009) The MRX complex stabilizes the replisome independently of the S phase checkpoint during replication stress. EMBO J., 28, 1142-1156.
    • (2009) EMBO J. , vol.28 , pp. 1142-1156
    • Tittel-Elmer, M.1
  • 59
    • 9644275421 scopus 로고    scopus 로고
    • Claspin and the activated form of ATR-ATRIP collaborate in the activation of Chk1
    • Kumagai,A. et al. (2004) Claspin and the activated form of ATR-ATRIP collaborate in the activation of Chk1. J. Biol. Chem., 279, 49599-49608.
    • (2004) J. Biol. Chem. , vol.279 , pp. 49599-49608
    • Kumagai, A.1
  • 60
    • 18244401922 scopus 로고    scopus 로고
    • Unwind and slow down: checkpoint activation by helicase and polymerase uncoupling
    • Cortez,D. (2005) Unwind and slow down: checkpoint activation by helicase and polymerase uncoupling. Genes Dev., 19, 1007-1012.
    • (2005) Genes Dev. , vol.19 , pp. 1007-1012
    • Cortez, D.1
  • 61
    • 32844461384 scopus 로고    scopus 로고
    • Phosphorylation of replication protein A by S-phase checkpoint kinases
    • Liu,J.S. et al. (2006) Phosphorylation of replication protein A by S-phase checkpoint kinases. DNA Repair (Amst.), 5, 369-380.
    • (2006) DNA Repair (Amst.) , vol.5 , pp. 369-380
    • Liu, J.S.1
  • 62
    • 29544437558 scopus 로고    scopus 로고
    • Multiple mechanisms control chromosome integrity after replication fork uncoupling and restart at irreparable UV lesions
    • Lopes,M. et al. (2006) Multiple mechanisms control chromosome integrity after replication fork uncoupling and restart at irreparable UV lesions. Mol. Cell, 21, 15-27.
    • (2006) Mol. Cell , vol.21 , pp. 15-27
    • Lopes, M.1
  • 63
    • 0041816064 scopus 로고    scopus 로고
    • The phosphorylation domain of the 32-kDa subunit of replication protein A (RPA) modulates RPA-DNA interactions. Evidence for an intersubunit interaction
    • Binz,S.K. et al. (2003) The phosphorylation domain of the 32-kDa subunit of replication protein A (RPA) modulates RPA-DNA interactions. Evidence for an intersubunit interaction. J. Biol. Chem., 278, 35584-35591.
    • (2003) J. Biol. Chem. , vol.278 , pp. 35584-35591
    • Binz, S.K.1
  • 64
    • 40849114493 scopus 로고    scopus 로고
    • Enhanced DNA-PK-mediated RPA2 hyperphosphorylation in DNA polymerase eta-deficient human cells treated with cisplatin and oxaliplatin
    • Cruet-Hennequart,S. et al. (2008) Enhanced DNA-PK-mediated RPA2 hyperphosphorylation in DNA polymerase eta-deficient human cells treated with cisplatin and oxaliplatin. DNA Repair (Amst.), 7, 582-596.
    • (2008) DNA Repair (Amst.) , vol.7 , pp. 582-596
    • Cruet-Hennequart, S.1
  • 65
    • 77953984959 scopus 로고    scopus 로고
    • Hyperphosphorylation of replication protein A in cisplatin-resistant and -sensitive head and neck squamous cell carcinoma cell lines
    • Sep 29
    • Manthey,K.C. et al. (2009 Sep 29) Hyperphosphorylation of replication protein A in cisplatin-resistant and -sensitive head and neck squamous cell carcinoma cell lines. Head Neck.
    • (2009) Head Neck
    • Manthey, K.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.