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Volumn 21, Issue 3-4, 2013, Pages 240-258

Contribution of SDF-1α/CXCR4 signaling to brain development and glioma progression

Author keywords

Brain; Cancer; Chemokines; Neuropathology

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CHEMOKINE RECEPTOR CXCR4; CLOTRIMAZOLE; DOPAMINE; FRACTALKINE; GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN DERIVATIVE; MIRTAZAPINE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PLERIXAFOR; PROSTAGLANDIN; PROTEIN KINASE B; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; STROMAL CELL DERIVED FACTOR 1ALPHA; TUMOR NECROSIS FACTOR ALPHA; 4 AMINOBUTYRIC ACID RECEPTOR; BASIC FIBROBLAST GROWTH FACTOR RECEPTOR; CANNABINOID; CHEMOKINE RECEPTOR CX3CR1; CHEMOKINE RECEPTOR CXCR7; COMPLEMENT COMPONENT C3A; CYCLIC AMP; DIPEPTIDYL PEPTIDASE IV; GLUTAMIC ACID; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MATRIX METALLOPROTEINASE; OPIATE; VASCULOTROPIN;

EID: 84878015545     PISSN: 1424862X     EISSN: 14248638     Source Type: Journal    
DOI: 10.1159/000339091     Document Type: Review
Times cited : (30)

References (203)
  • 1
    • 77953720207 scopus 로고    scopus 로고
    • The role of chemokine receptor CXCR4 in lung cancer
    • Gangadhar T, Nandi S, Salgia R: The role of chemokine receptor CXCR4 in lung cancer. Cancer Biol Ther 2010; 9: 409-416.
    • (2010) Cancer Biol Ther , vol.9 , pp. 409-416
    • Gangadhar, T.1    Nandi, S.2    Salgia, R.3
  • 4
    • 33747371948 scopus 로고    scopus 로고
    • Silencing of epithelial CXCL12 expression by DNA hypermethylation promotes colonic carcinoma metastasis
    • Wendt MK, Johanesen PA, Kang-Decker N, Binion DG, Shah V, Dwinell MB: Silencing of epithelial CXCL12 expression by DNA hypermethylation promotes colonic carcinoma metastasis. Oncogene 2006; 25: 4986- 4997.
    • (2006) Oncogene , vol.25 , pp. 4986-4997
    • Wendt, M.K.1    Johanesen, P.A.2    Kang-Decker, N.3    Binion, D.G.4    Shah, V.5    Dwinell, M.B.6
  • 5
    • 61449451621 scopus 로고    scopus 로고
    • The CXCR4/SDF-1 chemokine receptor axis: A new target therapeutic for non-small cell lung cancer
    • Otsuka S, Bebb G: The CXCR4/SDF-1 chemokine receptor axis: a new target therapeutic for non-small cell lung cancer. J Thorac Oncol 2008; 3: 1379-1383.
    • (2008) J Thorac Oncol , vol.3 , pp. 1379-1383
    • Otsuka, S.1    Bebb, G.2
  • 7
    • 68249122188 scopus 로고    scopus 로고
    • Functional diversity of SDF-1 splicing variants
    • Janowski M: Functional diversity of SDF-1 splicing variants. Cell Adh Migr 2009; 3: 243- 249.
    • (2009) Cell Adh Migr , vol.3 , pp. 243-249
    • Janowski, M.1
  • 8
    • 0141705319 scopus 로고    scopus 로고
    • Highly regionalized distribution of stromal cell-derived factor- 1/CXCL12 in adult rat brain: Constitutive expression in cholinergic, dopaminergic and vasopressinergic neurons
    • Banisadr G, Skrzydelski D, Kitabgi P, Rostene W, Parsadaniantz SM: Highly regionalized distribution of stromal cell-derived factor- 1/CXCL12 in adult rat brain: constitutive expression in cholinergic, dopaminergic and vasopressinergic neurons. Eur J Neurosci 2003; 18: 1593-1606.
    • (2003) Eur J Neurosci , vol.18 , pp. 1593-1606
    • Banisadr, G.1    Skrzydelski, D.2    Kitabgi, P.3    Rostene, W.4    Parsadaniantz, S.M.5
  • 9
    • 0034596584 scopus 로고    scopus 로고
    • Characterization and visualization of [125I] stromal cell-derived factor-1alpha binding to CXCR4 receptors in rat brain and human neuroblastoma cells
    • Banisadr G, Dicou E, Berbar T, Rostene W, Lombet A, Haour F: Characterization and visualization of [125I] stromal cell-derived factor-1alpha binding to CXCR4 receptors in rat brain and human neuroblastoma cells. J Neuroimmunol 2000; 110: 151-160.
    • (2000) J Neuroimmunol , vol.110 , pp. 151-160
    • Banisadr, G.1    Dicou, E.2    Berbar, T.3    Rostene, W.4    Lombet, A.5    Haour, F.6
  • 10
    • 0036435123 scopus 로고    scopus 로고
    • Neuroanatomical distribution of CXCR4 in adult rat brain and its localization in cholinergic and dopaminergic neurons
    • Banisadr G, Fontanges P, Haour F, Kitabgi P, Rostene W, Mélik Parsadaniantz S: Neuroanatomical distribution of CXCR4 in adult rat brain and its localization in cholinergic and dopaminergic neurons. Eur J Neurosci 2002; 16: 1661-1671.
    • (2002) Eur J Neurosci , vol.16 , pp. 1661-1671
    • Banisadr, G.1    Fontanges, P.2    Haour, F.3    Kitabgi, P.4    Rostene, W.5    Mélik Parsadaniantz, S.6
  • 11
    • 75349093215 scopus 로고    scopus 로고
    • Localization of CXCR4 in the forebrain of the adult rat
    • Trecki J, Brailoiu GC, Unterwald EM: Localization of CXCR4 in the forebrain of the adult rat. Brain Res 2010; 1315: 53-62.
    • (2010) Brain Res , vol.1315 , pp. 53-62
    • Trecki, J.1    Brailoiu, G.C.2    Unterwald, E.M.3
  • 13
    • 0034537408 scopus 로고    scopus 로고
    • Immunohistochemical analysis of CCR2, CCR3, CCR5, and CXCR4 in the human brain: Potential mechanisms for HIV dementia
    • van der Meer P, Ulrich AM, Gon?alez- Scarano F, Lavi E: Immunohistochemical analysis of CCR2, CCR3, CCR5, and CXCR4 in the human brain: potential mechanisms for HIV dementia. Exp Mol Pathol 2000; 69: 192-201.
    • (2000) Exp Mol Pathol , vol.69 , pp. 192-201
    • Van Der Meer, P.1    Ulrich, A.M.2    Gonalez-Scarano, F.3    Lavi, E.4
  • 14
    • 17944398503 scopus 로고    scopus 로고
    • Functional CXCR4 receptor development parallels sensitivity to HIV-1 gp120 in cultured rat astroglial cells but not in cultured rat cortical neurons
    • Köller H, Schaal H, Rosenbaum C, Czardybon M, Von Giesen HJ, Müller HW, Arendt G: Functional CXCR4 receptor development parallels sensitivity to HIV-1 gp120 in cultured rat astroglial cells but not in cultured rat cortical neurons. J Neurovirol 2002; 8: 411-419.
    • (2002) J Neurovirol , vol.8 , pp. 411-419
    • Köller, H.1    Schaal, H.2    Rosenbaum, C.3    Czardybon, M.4    Von Giesen, H.J.5    Müller, H.W.6    Arendt, G.7
  • 18
    • 50249188848 scopus 로고    scopus 로고
    • Regional and cellular localization of the CXCl12/SDF-1 chemokine receptor CXCR7 in the developing and adult rat brain
    • Schönemeier B, Kolodziej A, Schulz S, Jacobs S, Hoellt V, Stumm R: Regional and cellular localization of the CXCl12/SDF-1 chemokine receptor CXCR7 in the developing and adult rat brain. J Comp Neurol 2008; 510: 207-220.
    • (2008) J Comp Neurol , vol.510 , pp. 207-220
    • Schönemeier, B.1    Kolodziej, A.2    Schulz, S.3    Jacobs, S.4    Hoellt, V.5    Stumm, R.6
  • 20
    • 0031738366 scopus 로고    scopus 로고
    • CXCR-4, a chemokine receptor, is overexpressed in and required for proliferation of glioblastoma tumor cells
    • Sehgal A, Keener C, Boynton AL, Warrick J, Murphy GP: CXCR-4, a chemokine receptor, is overexpressed in and required for proliferation of glioblastoma tumor cells. J Surg Oncol 1998; 69: 99-104.
    • (1998) J Surg Oncol , vol.69 , pp. 99-104
    • Sehgal, A.1    Keener, C.2    Boynton, A.L.3    Warrick, J.4    Murphy, G.P.5
  • 21
    • 0033959917 scopus 로고    scopus 로고
    • Identification and localization of the cytokine SDF1 and its receptor, CXC chemokine receptor 4, to regions of necrosis and angiogenesis in human glioblastoma
    • Rempel SA, Dudas S, Ge S, Gutiérrez JA: Identification and localization of the cytokine SDF1 and its receptor, CXC chemokine receptor 4, to regions of necrosis and angiogenesis in human glioblastoma. Clin Cancer Res 2000; 6: 102-111.
    • (2000) Clin Cancer Res , vol.6 , pp. 102-111
    • Rempel, S.A.1    Dudas, S.2    Ge, S.3    Gutiérrez, J.A.4
  • 22
    • 58149290094 scopus 로고    scopus 로고
    • CXCR4 expression is elevated in glioblastoma mul tiforme and correlates with an increase in intensity and extent of peri tumoral T2-weighted magnetic resonance imaging signal abnormalities
    • discussion 569-570
    • Stevenson CB, Ehtesham M, McMillan KM, Valadez JG, Edgeworth ML, Price RR, Abel TW, Mapara KY, Thompson RC: CXCR4 expression is elevated in glioblastoma mul tiforme and correlates with an increase in intensity and extent of peri tumoral T2-weighted magnetic resonance imaging signal abnormalities. Neurosurgery 2008; 63: 560-569; discussion 569- 570.
    • (2008) Neurosurgery , vol.63 , pp. 560-569
    • Stevenson, C.B.1    Ehtesham, M.2    McMillan, K.M.3    Valadez, J.G.4    Edgeworth, M.L.5    Price, R.R.6    Abel, T.W.7    Mapara, K.Y.8    Thompson, R.C.9
  • 24
    • 29244445813 scopus 로고    scopus 로고
    • Widespread CXCR4 activation in astrocytomas revealed by phospho- CXCR4-specific antibodies
    • Woerner BM, Warrington NM, Kung AL, Perry A, Rubin JB: Widespread CXCR4 activation in astrocytomas revealed by phospho- CXCR4-specific antibodies. Cancer Res 2005; 65: 11392-11399.
    • (2005) Cancer Res , vol.65 , pp. 11392-11399
    • Woerner, B.M.1    Warrington, N.M.2    Kung, A.L.3    Perry, A.4    Rubin, J.B.5
  • 27
    • 64549100787 scopus 로고    scopus 로고
    • Expression of CXCL12 on pseudopalisading cells and proliferating microvessels in glioblastomas: An accelerated growth factor in glioblastomas
    • Komatani H, Sugita Y, Arakawa F, Ohshima K, Shigemori M: Expression of CXCL12 on pseudopalisading cells and proliferating microvessels in glioblastomas: an accelerated growth factor in glioblastomas. Int J Oncol 2009; 34: 665-672.
    • (2009) Int J Oncol , vol.34 , pp. 665-672
    • Komatani, H.1    Sugita, Y.2    Arakawa, F.3    Ohshima, K.4    Shigemori, M.5
  • 29
    • 42449103074 scopus 로고    scopus 로고
    • Nestin, PDGFRbeta, CXCL12 and VEGF in glioma patients: Different profiles of (pro-angiogenic) molecule expression are related with tumor grade and
    • may provide prognostic information
    • Maderna E, Salmaggi A, Calatozzolo C, Limido L, Pollo B: Nestin, PDGFRbeta, CXCL12 and VEGF in glioma patients: different profiles of (pro-angiogenic) molecule expression are related with tumor grade and may provide prognostic information. Cancer Biol Ther 2007; 6: 1018-1024.
    • (2007) Cancer Biol Ther , vol.6 , pp. 1018-1024
    • Maderna, E.1    Salmaggi, A.2    Calatozzolo, C.3    Limido, L.4    Pollo, B.5
  • 31
    • 33751557620 scopus 로고    scopus 로고
    • CXCL12 limits inflammation by localizing mononuclear infiltrates to the perivascular space during experimental autoimmune encephalomyelitis
    • McCandless EE, Wang Q, Woerner BM, Harper JM, Klein RS: CXCL12 limits inflammation by localizing mononuclear infiltrates to the perivascular space during experimental autoimmune encephalomyelitis. J Immunol 2006; 177: 8053-8064.
    • (2006) J Immunol , vol.177 , pp. 8053-8064
    • McCandless, E.E.1    Wang, Q.2    Woerner, B.M.3    Harper, J.M.4    Klein, R.S.5
  • 32
    • 0037414821 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1alpha induces tube-like structure formation of endothelial cells through phosphoinositide 3-kinase
    • Kanda S, Mochizuki Y, Kanetake H: Stromal cell-derived factor-1alpha induces tube-like structure formation of endothelial cells through phosphoinositide 3-kinase. J Biol Chem 2003; 278: 257-262.
    • (2003) J Biol Chem , vol.278 , pp. 257-262
    • Kanda, S.1    Mochizuki, Y.2    Kanetake, H.3
  • 34
    • 48749124404 scopus 로고    scopus 로고
    • Hypoxia- and vascular endothelial growth factor-induced stromal cell-derived factor-1alpha/CXCR4 expression in glioblastomas: One plausible explanation of Scherer's structures
    • Zagzag D, Esencay M, Mendez O, Yee H, Smirnova I, Huang Y, Chiriboga L, Lukyanov E, Liu M, Newcomb EW: Hypoxia- and vascular endothelial growth factor-induced stromal cell-derived factor-1alpha/CXCR4 expression in glioblastomas: one plausible explanation of Scherer's structures. Am J Pathol 2008; 173: 545-560.
    • (2008) Am J Pathol , vol.173 , pp. 545-560
    • Zagzag, D.1    Esencay, M.2    Mendez, O.3    Yee, H.4    Smirnova, I.5    Huang, Y.6    Chiriboga, L.7    Lukyanov, E.8    Liu, M.9    Newcomb, E.W.10
  • 35
    • 56649120579 scopus 로고    scopus 로고
    • Down-regulation of CXCL12 mRNA expression by promoter hypermethylation and its association with metastatic progression in human breast carcinomas
    • Zhou W, Jiang Z, Liu N, Xu F, Wen P, Liu Y, Zhong W, Song X, Chang X, Zhang X, Wei G, Yu J: Down-regulation of CXCL12 mRNA expression by promoter hypermethylation and its association with metastatic progression in human breast carcinomas. J Cancer Res Clin Oncol 2009; 135: 91-102.
    • (2009) J Cancer Res Clin Oncol , vol.135 , pp. 91-102
    • Zhou, W.1    Jiang, Z.2    Liu, N.3    Xu, F.4    Wen, P.5    Liu, Y.6    Zhong, W.7    Song, X.8    Chang, X.9    Zhang, X.10    Wei, G.11    Yu, J.12
  • 37
    • 39849096261 scopus 로고    scopus 로고
    • Epigenetic silencing of CXCL12 increases the metastatic potential of mammary carcinoma cells
    • Wendt MK, Cooper AN, Dwinell MB: Epigenetic silencing of CXCL12 increases the metastatic potential of mammary carcinoma cells. Oncogene 2008; 27: 1461-1471.
    • (2008) Oncogene , vol.27 , pp. 1461-1471
    • Wendt, M.K.1    Cooper, A.N.2    Dwinell, M.B.3
  • 38
    • 0037447318 scopus 로고    scopus 로고
    • Stromal cell-derived factor 1alpha stimulates human glioblastoma cell growth through the activation of both extracellular signal-regulated kinases 1/2 and Akt
    • Barbero S, Bonavia R, Bajetto A, Porcile C, Pirani P, Ravetti JL, Zona GL, Spaziante R, Florio T, Schettini G: Stromal cell-derived factor 1alpha stimulates human glioblastoma cell growth through the activation of both extracellular signal-regulated kinases 1/2 and Akt. Cancer Res 2003; 63: 1969-1974.
    • (2003) Cancer Res , vol.63 , pp. 1969-1974
    • Barbero, S.1    Bonavia, R.2    Bajetto, A.3    Porcile, C.4    Pirani, P.5    Ravetti, J.L.6    Zona, G.L.7    Spaziante, R.8    Florio, T.9    Schettini, G.10
  • 40
    • 77958028254 scopus 로고    scopus 로고
    • Galvez- Contreras AY: Immune system modulates the function of adult neural stem cells
    • Gonzalez-Perez O, Jauregui-Huerta F, Galvez- Contreras AY: Immune system modulates the function of adult neural stem cells. Curr Immunol Rev 2010; 6: 167-173.
    • (2010) Curr Immunol Rev , vol.6 , pp. 167-173
    • Gonzalez-Perez, O.1    Jauregui-Huerta, F.2
  • 41
    • 34247369706 scopus 로고    scopus 로고
    • Stromal derived factor-1 exerts differential regulation on distinct cortical cell populations in vitro
    • Pritchett J, Wright C, Zeef L, Nadarajah B: Stromal derived factor-1 exerts differential regulation on distinct cortical cell populations in vitro. BMC Dev Biol 2007; 7: 31.
    • (2007) BMC Dev Biol , vol.7 , pp. 31
    • Pritchett, J.1    Wright, C.2    Zeef, L.3    Nadarajah, B.4
  • 42
    • 1542345773 scopus 로고    scopus 로고
    • Expression of the chemokine receptor Cxcr4 mRNA during mouse brain development
    • Tissir F, Wang CE, Goffinet AM: Expression of the chemokine receptor Cxcr4 mRNA during mouse brain development. Brain Res Dev Brain Res 2004; 149: 63-71.
    • (2004) Brain Res Dev Brain Res , vol.149 , pp. 63-71
    • Tissir, F.1    Wang, C.E.2    Goffinet, A.M.3
  • 44
    • 1842584928 scopus 로고    scopus 로고
    • Stromal cell-derived factor 1-mediated CXCR4 signaling in rat and human cortical neural progenitor cells
    • Peng H, Huang Y, Rose J, Erichsen D, Herek S, Fujii N, Tamamura H, Zheng J: Stromal cell-derived factor 1-mediated CXCR4 signaling in rat and human cortical neural progenitor cells. J Neurosci Res 2004; 76: 35-50.
    • (2004) J Neurosci Res , vol.76 , pp. 35-50
    • Peng, H.1    Huang, Y.2    Rose, J.3    Erichsen, D.4    Herek, S.5    Fujii, N.6    Tamamura, H.7    Zheng, J.8
  • 45
    • 0348141712 scopus 로고    scopus 로고
    • Chemokines promote quiescence and survival of human neural progenitor cells
    • Krathwohl MD, Kaiser JL: Chemokines promote quiescence and survival of human neural progenitor cells. Stem Cells 2004; 22: 109-118.
    • (2004) Stem Cells , vol.22 , pp. 109-118
    • Krathwohl, M.D.1    Kaiser, J.L.2
  • 46
    • 78349287682 scopus 로고    scopus 로고
    • Chemokine receptor CXCR4 signaling modulates the growth factor-induced cell cycle of self-renewing and multipotent neural progenitor cells
    • Li M, Chang CJ, Lathia JD, Wang L, Pacenta HL, Cotleur A, Ransohoff RM: Chemokine receptor CXCR4 signaling modulates the growth factor-induced cell cycle of self-renewing and multipotent neural progenitor cells. Glia 2011; 59: 108-118.
    • (2011) Glia , vol.59 , pp. 108-118
    • Li, M.1    Chang, C.J.2    Lathia, J.D.3    Wang, L.4    Pacenta, H.L.5    Cotleur, A.6    Ransohoff, R.M.7
  • 47
    • 38749136238 scopus 로고    scopus 로고
    • Multiple roles of chemokine CXCL12 in the central nervous system: A migration from immunology to neurobiology
    • Li M, Ransohoff RM: Multiple roles of chemokine CXCL12 in the central nervous system: a migration from immunology to neurobiology. Prog Neurobiol 2008; 84: 116-131.
    • (2008) Prog Neurobiol , vol.84 , pp. 116-131
    • Li, M.1    Ransohoff, R.M.2
  • 48
    • 33748987637 scopus 로고    scopus 로고
    • Meninges control tangential migration of hem-derived Cajal- Retzius cells via CXCL12/CXCR4 signaling
    • Borrell V, Marín O: Meninges control tangential migration of hem-derived Cajal- Retzius cells via CXCL12/CXCR4 signaling. Nat Neurosci 2006; 9: 1284-1293.
    • (2006) Nat Neurosci , vol.9 , pp. 1284-1293
    • Borrell, V.1    Marín, O.2
  • 49
    • 33748693511 scopus 로고    scopus 로고
    • Stromal-derived factor-1 (CXCL12) regulates laminar position of Cajal-Retzius cells in normal and dysplastic brains
    • Paredes MF, Li G, Berger O, Baraban SC, Pleasure SJ: Stromal-derived factor-1 (CXCL12) regulates laminar position of Cajal-Retzius cells in normal and dysplastic brains. J Neurosci 2006; 26: 9404-9412.
    • (2006) J Neurosci , vol.26 , pp. 9404-9412
    • Paredes, M.F.1    Li, G.2    Berger, O.3    Baraban, S.C.4    Pleasure, S.J.5
  • 51
    • 78049469834 scopus 로고    scopus 로고
    • Distinctive properties of CXC chemokine receptor 4-expressing Cajal-Retzius cells versus GABAergic interneurons of the postnatal hippocampus
    • Marchionni I, Takács VT, Nunzi MG, Mugnaini E, Miller RJ, Maccaferri G: Distinctive properties of CXC chemokine receptor 4-expressing Cajal-Retzius cells versus GABAergic interneurons of the postnatal hippocampus. J Physiol 2010; 588: 2859-2878.
    • (2010) J Physiol , vol.588 , pp. 2859-2878
    • Marchionni, I.1    Takács, V.T.2    Nunzi, M.G.3    Mugnaini, E.4    Miller, R.J.5    MacCaferri, G.6
  • 52
    • 0036326271 scopus 로고    scopus 로고
    • Role of the chemokine SDF-1 as the meningeal attractant for embryonic cerebellar neurons
    • Zhu Y, Yu T, Zhang XC, Nagasawa T, Wu JY, Rao Y: Role of the chemokine SDF-1 as the meningeal attractant for embryonic cerebellar neurons. Nat Neurosci 2002; 5: 719-720.
    • (2002) Nat Neurosci , vol.5 , pp. 719-720
    • Zhu, Y.1    Yu, T.2    Zhang, X.C.3    Nagasawa, T.4    Wu, J.Y.5    Rao, Y.6
  • 53
    • 77957226986 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1 promotes migration of cells from the upper rhombic lip in cerebellar development
    • Yu T, Huang H, Li HF: Stromal cell-derived factor-1 promotes migration of cells from the upper rhombic lip in cerebellar development. J Neurosci Res 2010; 88: 2775-2786.
    • (2010) J Neurosci Res , vol.88 , pp. 2775-2786
    • Yu, T.1    Huang, H.2    Li, H.F.3
  • 56
    • 62349114345 scopus 로고    scopus 로고
    • Identification of a transient subpial neurogenic zone in the developing dentate gyrus and its regulation by Cxcl12 and reelin signaling
    • Li G, Kataoka H, Coughlin SR, Pleasure SJ: Identification of a transient subpial neurogenic zone in the developing dentate gyrus and its regulation by Cxcl12 and reelin signaling. Development 2009; 136: 327-335.
    • (2009) Development , vol.136 , pp. 327-335
    • Li, G.1    Kataoka, H.2    Coughlin, S.R.3    Pleasure, S.J.4
  • 57
    • 0037076290 scopus 로고    scopus 로고
    • Abnormal development of the hippocampal dentate gyrus in mice lacking the CXCR4 chemokine receptor
    • Lu M, Grove EA, Miller RJ: Abnormal development of the hippocampal dentate gyrus in mice lacking the CXCR4 chemokine receptor. Proc Natl Acad Sci USA 2002; 99: 7090-7095.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 7090-7095
    • Lu, M.1    Grove, E.A.2    Miller, R.J.3
  • 58
    • 51149106566 scopus 로고    scopus 로고
    • Regulation of axonal elongation and pathfinding from the entorhinal cortex to the dentate gyrus in the hippocampus by the chemokine stromal cell-derived factor 1 alpha
    • Ohshima Y, Kubo T, Koyama R, Ueno M, Nakagawa M, Yamashita T: Regulation of axonal elongation and pathfinding from the entorhinal cortex to the dentate gyrus in the hippocampus by the chemokine stromal cell-derived factor 1 alpha. J Neurosci 2008; 28: 8344-8353.
    • (2008) J Neurosci , vol.28 , pp. 8344-8353
    • Ohshima, Y.1    Kubo, T.2    Koyama, R.3    Ueno, M.4    Nakagawa, M.5    Yamashita, T.6
  • 59
    • 33845571563 scopus 로고    scopus 로고
    • Expression of SDF-1 and CXCR4 during reorganization of the postnatal dentate gyrus
    • Berger O, Li G, Han SM, Paredes M, Pleasure SJ: Expression of SDF-1 and CXCR4 during reorganization of the postnatal dentate gyrus. Dev Neurosci 2007; 29: 48-58.
    • (2007) Dev Neurosci , vol.29 , pp. 48-58
    • Berger, O.1    Li, G.2    Han, S.M.3    Paredes, M.4    Pleasure, S.J.5
  • 60
    • 48549088793 scopus 로고    scopus 로고
    • The chemokine stromal cell-derived factor-1 regulates GABAergic inputs to neural progenitors in the postnatal dentate gyrus
    • Bhattacharyya BJ, Banisadr G, Jung H, Ren D, Cronshaw DG, Zou Y, Miller RJ: The chemokine stromal cell-derived factor-1 regulates GABAergic inputs to neural progenitors in the postnatal dentate gyrus. J Neurosci 2008; 28: 6720-6730.
    • (2008) J Neurosci , vol.28 , pp. 6720-6730
    • Bhattacharyya, B.J.1    Banisadr, G.2    Jung, H.3    Ren, D.4    Cronshaw, D.G.5    Zou, Y.6    Miller, R.J.7
  • 63
    • 0037030677 scopus 로고    scopus 로고
    • Origin of GABAergic neurons in the human neocortex
    • Letinic K, Zoncu R, Rakic P: Origin of GABAergic neurons in the human neocortex. Nature 2002; 417: 645-649.
    • (2002) Nature , vol.417 , pp. 645-649
    • Letinic, K.1    Zoncu, R.2    Rakic, P.3
  • 64
    • 33845748152 scopus 로고    scopus 로고
    • Molecular interaction between projection neuron precursors and invading interneurons via stromal-derived factor 1 (CXCL12)/ CXCR4 signaling in the cortical subventricular zone/intermediate zone
    • Tiveron MC, Rossel M, Moepps B, Zhang YL, Seidenfaden R, Favor J, König N, Cremer H: Molecular interaction between projection neuron precursors and invading interneurons via stromal-derived factor 1 (CXCL12)/ CXCR4 signaling in the cortical subventricular zone/intermediate zone. J Neurosci 2006; 26: 13273-13278.
    • (2006) J Neurosci , vol.26 , pp. 13273-13278
    • Tiveron, M.C.1    Rossel, M.2    Moepps, B.3    Zhang, Y.L.4    Seidenfaden, R.5    Favor, J.6    König, N.7    Cremer, H.8
  • 66
    • 78349270149 scopus 로고    scopus 로고
    • CXCR4 is required for proper regional and laminar distribution of cortical somatostatin-, calretinin-, and neuropeptide Y-expressing GABAergic interneurons
    • Tanaka DH, Mikami S, Nagasawa T, Miyazaki J, Nakajima K, Murakami F: CXCR4 is required for proper regional and laminar distribution of cortical somatostatin-, calretinin-, and neuropeptide Y-expressing GABAergic interneurons. Cereb Cortex 2010; 20: 2810-2817.
    • (2010) Cereb Cortex , vol.20 , pp. 2810-2817
    • Tanaka, D.H.1    Mikami, S.2    Nagasawa, T.3    Miyazaki, J.4    Nakajima, K.5    Murakami, F.6
  • 67
    • 33947524099 scopus 로고    scopus 로고
    • Lhx6 activity is required for the normal migration and specification of cortical interneuron subtypes
    • Liodis P, Denaxa M, Grigoriou M, Akufo- Addo C, Yanagawa Y, Pachnis V: Lhx6 activity is required for the normal migration and specification of cortical interneuron subtypes. J Neurosci 2007; 27: 3078-3089.
    • (2007) J Neurosci , vol.27 , pp. 3078-3089
    • Liodis, P.1    Denaxa, M.2    Grigoriou, M.3    Akufo- Addo, C.4    Yanagawa, Y.5    Pachnis, V.6
  • 68
    • 38749093332 scopus 로고    scopus 로고
    • Regional distribution of cortical interneurons and development of inhibitory tone are regulated by Cxcl12/Cxcr4 signaling
    • Li G, Adesnik H, Li J, Long J, Nicoll RA, Rubenstein JL, Pleasure SJ: Regional distribution of cortical interneurons and development of inhibitory tone are regulated by Cxcl12/Cxcr4 signaling. J Neurosci 2008; 28: 1085-1098.
    • (2008) J Neurosci , vol.28 , pp. 1085-1098
    • Li, G.1    Adesnik, H.2    Li, J.3    Long, J.4    Nicoll, R.A.5    Rubenstein, J.L.6    Pleasure, S.J.7
  • 69
    • 34147112805 scopus 로고    scopus 로고
    • Patterns of SDF-1alpha and SDF- 1gamma mRNAs, migration pathways, and phenotypes of CXCR4-expressing neurons in the developing rat telencephalon
    • Stumm R, Kolodziej A, Schulz S, Kohtz JD, Höllt V: Patterns of SDF-1alpha and SDF- 1gamma mRNAs, migration pathways, and phenotypes of CXCR4-expressing neurons in the developing rat telencephalon. J Comp Neurol 2007; 502: 382-399.
    • (2007) J Comp Neurol , vol.502 , pp. 382-399
    • Stumm, R.1    Kolodziej, A.2    Schulz, S.3    Kohtz, J.D.4    Höllt, V.5
  • 70
    • 37149006979 scopus 로고    scopus 로고
    • Stromal-derived factor signalling regulates radial and tangential migration in the developing cerebral cortex
    • Liapi A, Pritchett J, Jones O, Fujii N, Parnavelas JG, Nadarajah B: Stromal-derived factor signalling regulates radial and tangential migration in the developing cerebral cortex. Dev Neurosci 2008; 30: 117-131.
    • (2008) Dev Neurosci , vol.30 , pp. 117-131
    • Liapi, A.1    Pritchett, J.2    Jones, O.3    Fujii, N.4    Parnavelas, J.G.5    Nadarajah, B.6
  • 71
    • 54049138890 scopus 로고    scopus 로고
    • SDF1alpha/CXCR4 signaling, via ERKs and the transcription factor Egr1, induces expression of a 67-kDa form of glutamic acid decarboxylase in embryonic hippocampal neurons
    • Luo Y, Lathia J, Mughal M, Mattson MP: SDF1alpha/CXCR4 signaling, via ERKs and the transcription factor Egr1, induces expression of a 67-kDa form of glutamic acid decarboxylase in embryonic hippocampal neurons. J Biol Chem 2008; 283: 24789-24800.
    • (2008) J Biol Chem , vol.283 , pp. 24789-24800
    • Luo, Y.1    Lathia, J.2    Mughal, M.3    Mattson, M.P.4
  • 73
    • 16844382247 scopus 로고    scopus 로고
    • The chemokine SDF-1 differentially regulates axonal elongation and branching in hippocampal neurons
    • Pujol F, Kitabgi P, Boudin H: The chemokine SDF-1 differentially regulates axonal elongation and branching in hippocampal neurons. J Cell Sci 2005; 118: 1071-1080.
    • (2005) J Cell Sci , vol.118 , pp. 1071-1080
    • Pujol, F.1    Kitabgi, P.2    Boudin, H.3
  • 75
    • 33748939378 scopus 로고    scopus 로고
    • Dendrite-selective redistribution of the chemokine receptor CXCR4 following agonist stimulation
    • Baudouin SJ, Pujol F, Nicot A, Kitabgi P, Boudin H: Dendrite-selective redistribution of the chemokine receptor CXCR4 following agonist stimulation. Mol Cell Neurosci 2006; 33: 160-169.
    • (2006) Mol Cell Neurosci , vol.33 , pp. 160-169
    • Baudouin, S.J.1    Pujol, F.2    Nicot, A.3    Kitabgi, P.4    Boudin, H.5
  • 76
    • 34447525422 scopus 로고    scopus 로고
    • Cxcl12/ Cxcr4 chemokine signaling is required for placode assembly and sensory axon pathfinding in the zebrafish olfactory system
    • Miyasaka N, Knaut H, Yoshihara Y: Cxcl12/ Cxcr4 chemokine signaling is required for placode assembly and sensory axon pathfinding in the zebrafish olfactory system. Development 2007; 134: 2459-2468.
    • (2007) Development , vol.134 , pp. 2459-2468
    • Miyasaka, N.1    Knaut, H.2    Yoshihara, Y.3
  • 78
    • 0036277443 scopus 로고    scopus 로고
    • Stimulation of chemokine CXC receptor induces synaptic depression of evoked parallel fibers inputs onto Purkinje neurons in mouse cerebellum
    • Ragozzino D, Renzi M, Giovannelli A, Eusebi F: Stimulation of chemokine CXC receptor induces synaptic depression of evoked parallel fibers inputs onto Purkinje neurons in mouse cerebellum. J Neuroimmunol 2002; 127: 30-36.
    • (2002) J Neuroimmunol , vol.127 , pp. 30-36
    • Ragozzino, D.1    Renzi, M.2    Giovannelli, A.3    Eusebi, F.4
  • 79
    • 14944338800 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1alpha directly modulates voltage-dependent currents of the action potential in mammalian neuronal cells
    • Guyon A, Rovere C, Cervantes A, Allaeys I, Nahon JL: Stromal cell-derived factor-1alpha directly modulates voltage-dependent currents of the action potential in mammalian neuronal cells. J Neurochem 2005; 93: 963-973.
    • (2005) J Neurochem , vol.93 , pp. 963-973
    • Guyon, A.1    Rovere, C.2    Cervantes, A.3    Allaeys, I.4    Nahon, J.L.5
  • 80
    • 0037704447 scopus 로고    scopus 로고
    • Frequency modulation of synchronized Ca2+ spikes in cultured hippocampal networks through G-protein-coupled receptors
    • Liu Z, Geng L, Li R, He X, Zheng JQ, Xie Z: Frequency modulation of synchronized Ca2+ spikes in cultured hippocampal networks through G-protein-coupled receptors. J Neurosci 2003; 23: 4156-4163.
    • (2003) J Neurosci , vol.23 , pp. 4156-4163
    • Liu, Z.1    Geng, L.2    Li, R.3    He, X.4    Zheng, J.Q.5    Xie, Z.6
  • 81
    • 36649019529 scopus 로고    scopus 로고
    • Role of giant depolarizing potentials in shaping synaptic currents in the developing hippocampus
    • Mohajerani MH, Cherubini E: Role of giant depolarizing potentials in shaping synaptic currents in the developing hippocampus. Crit Rev Neurobiol 2006; 18: 13-23.
    • (2006) Crit Rev Neurobiol , vol.18 , pp. 13-23
    • Mohajerani, M.H.1    Cherubini, E.2
  • 82
    • 43249107304 scopus 로고    scopus 로고
    • Modulation of network-driven, GABAmediated giant depolarizing potentials by SDF-1alpha in the developing hippocampus
    • Kasiyanov A, Fujii N, Tamamura H, Xiong H: Modulation of network-driven, GABAmediated giant depolarizing potentials by SDF-1alpha in the developing hippocampus. Dev Neurosci 2008; 30: 285-292.
    • (2008) Dev Neurosci , vol.30 , pp. 285-292
    • Kasiyanov, A.1    Fujii, N.2    Tamamura, H.3    Xiong, H.4
  • 83
    • 43749111561 scopus 로고    scopus 로고
    • Tonic activation of CXC chemokine receptor in immature granule cells supports neurogenesis in the adult dentate gyrus
    • Kolodziej A, Schulz S, Guyon A, Wu DF, Pfeiffer M, Odemis V, Höllt V, Stumm R: Tonic activation of CXC chemokine receptor in immature granule cells supports neurogenesis in the adult dentate gyrus. J Neurosci 2008; 28: 4488-4500.
    • (2008) J Neurosci , vol.28 , pp. 4488-4500
    • Kolodziej, A.1    Schulz, S.2    Guyon, A.3    Wu, D.F.4    Pfeiffer, M.5    Odemis, V.6    Höllt, V.7    Stumm, R.8
  • 84
    • 69549120552 scopus 로고    scopus 로고
    • SDF1/CXCR4 signalling regulates two distinct processes of precerebellar neuronal migration and its depletion leads to abnormal pontine nuclei formation
    • Zhu Y, Matsumoto T, Mikami S, Nagasawa T, Murakami F: SDF1/CXCR4 signalling regulates two distinct processes of precerebellar neuronal migration and its depletion leads to abnormal pontine nuclei formation. Development 2009; 136: 1919-1928.
    • (2009) Development , vol.136 , pp. 1919-1928
    • Zhu, Y.1    Matsumoto, T.2    Mikami, S.3    Nagasawa, T.4    Murakami, F.5
  • 85
    • 20044391264 scopus 로고    scopus 로고
    • A role for CXCR4 signaling in survival and migration of neural and oligodendrocyte precursors
    • Dziembowska M, Tham TN, Lau P, Vitry S, Lazarini F, Dubois-Dalcq M: A role for CXCR4 signaling in survival and migration of neural and oligodendrocyte precursors. Glia 2005; 50: 258-269.
    • (2005) Glia , vol.50 , pp. 258-269
    • Dziembowska, M.1    Tham, T.N.2    Lau, P.3    Vitry, S.4    Lazarini, F.5    Dubois-Dalcq, M.6
  • 86
    • 33745635102 scopus 로고    scopus 로고
    • Differential effects of chemokines on oligodendrocyte precursor proliferation and myelin formation in vitro
    • Kadi L, Selvaraju R, de Lys P, Proudfoot AE, Wells TN, Boschert U: Differential effects of chemokines on oligodendrocyte precursor proliferation and myelin formation in vitro. J Neuroimmunol 2006; 174: 133-146.
    • (2006) J Neuroimmunol , vol.174 , pp. 133-146
    • Kadi, L.1    Selvaraju, R.2    De Lys, P.3    Proudfoot, A.E.4    Wells, T.N.5    Boschert, U.6
  • 87
    • 77954653333 scopus 로고    scopus 로고
    • CXCR4 promotes differentiation of oligodendrocyte progenitors and remyelination
    • Patel JR, McCandless EE, Dorsey D, Klein RS: CXCR4 promotes differentiation of oligodendrocyte progenitors and remyelination. Proc Natl Acad Sci USA 2010; 107: 11062-11067.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 11062-11067
    • Patel, J.R.1    McCandless, E.E.2    Dorsey, D.3    Klein, R.S.4
  • 88
    • 77955089959 scopus 로고    scopus 로고
    • CXCR4-mediated glutamate exocytosis from astrocytes
    • Cali C, Bezzi P: CXCR4-mediated glutamate exocytosis from astrocytes. J Neuroimmunol 2010; 224: 13-21.
    • (2010) J Neuroimmunol , vol.224 , pp. 13-21
    • Cali, C.1    Bezzi, P.2
  • 92
    • 56849112798 scopus 로고    scopus 로고
    • Functional expression of CXCR4 in somatotrophs: CXCL12 activates GH gene, GH production and secretion, and cellular proliferation
    • Lee Y, Kim JM, Lee EJ: Functional expression of CXCR4 in somatotrophs: CXCL12 activates GH gene, GH production and secretion, and cellular proliferation. J Endocrinol 2008; 199: 191-199.
    • (2008) J Endocrinol , vol.199 , pp. 191-199
    • Lee, Y.1    Kim, J.M.2    Lee, E.J.3
  • 93
    • 71549145276 scopus 로고    scopus 로고
    • Cxcl12a- Cxcr4b signaling is important for proper development of the forebrain GnRH system in zebrafish
    • Palevitch O, Abraham E, Borodovsky N, Levkowitz G, Zohar Y, Gothilf Y: Cxcl12a- Cxcr4b signaling is important for proper development of the forebrain GnRH system in zebrafish. Gen Comp Endocrinol 2010; 165: 262-268.
    • (2010) Gen Comp Endocrinol , vol.165 , pp. 262-268
    • Palevitch, O.1    Abraham, E.2    Borodovsky, N.3    Levkowitz, G.4    Zohar, Y.5    Gothilf, Y.6
  • 94
    • 33745791807 scopus 로고    scopus 로고
    • Stromal cell-derived factor- chemokine C-X-C motif ligand 12) and chemokine C-X-C motif receptor 4 are required for migration of gonadotropin-releasing hormone neurons to the forebrain
    • Schwarting GA, Henion TR, Nugent JD, Caplan B, Tobet S: Stromal cell-derived factor- (chemokine C-X-C motif ligand 12) and chemokine C-X-C motif receptor 4 are required for migration of gonadotropin-releasing hormone neurons to the forebrain. J Neurosci 2006; 26: 6834-6840.
    • (2006) J Neurosci , vol.26 , pp. 6834-6840
    • Schwarting, G.A.1    Henion, T.R.2    Nugent, J.D.3    Caplan, B.4    Tobet, S.5
  • 95
    • 40149092970 scopus 로고    scopus 로고
    • CXCR4/ SDF-1 system modulates development of GnRH-1 neurons and the olfactory system
    • Toba Y, Tiong JD, Ma Q, Wray S: CXCR4/ SDF-1 system modulates development of GnRH-1 neurons and the olfactory system. Dev Neurobiol 2008; 68: 487-503.
    • (2008) Dev Neurobiol , vol.68 , pp. 487-503
    • Toba, Y.1    Tiong, J.D.2    Ma, Q.3    Wray, S.4
  • 98
    • 37549028470 scopus 로고    scopus 로고
    • Cellular and subcellular evidence for neuronal interaction between the chemokine stromal cellderived factor-1/CXCL 12 and vasopressin: Regulation in the hypothalamo-neurohypophysial system of the Brattleboro rats
    • Callewaere C, Fernette B, Raison D, Mechighel P, Burlet A, Calas A, Kitabgi P, Parsadaniantz SM, Rostene W: Cellular and subcellular evidence for neuronal interaction between the chemokine stromal cellderived factor-1/CXCL 12 and vasopressin: regulation in the hypothalamo-neurohypophysial system of the Brattleboro rats. Endocrinology 2008; 149: 310-319.
    • (2008) Endocrinology , vol.149 , pp. 310-319
    • Callewaere, C.1    Fernette, B.2    Raison, D.3    Mechighel, P.4    Burlet, A.5    Calas, A.6    Kitabgi, P.7    Parsadaniantz, S.M.8    Rostene, W.9
  • 99
    • 70349909667 scopus 로고    scopus 로고
    • CXCR4 and CXCL12 expression is increased in the nigro-striatal system of Parkinson's disease
    • Shimoji M, Pagan F, Healton EB, Mocchetti I: CXCR4 and CXCL12 expression is increased in the nigro-striatal system of Parkinson's disease. Neurotox Res 2009; 16: 318-328.
    • (2009) Neurotox Res , vol.16 , pp. 318-328
    • Shimoji, M.1    Pagan, F.2    Healton, E.B.3    Mocchetti, I.4
  • 102
    • 33644788307 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1alpha modulation of the excitability of rat substantia nigra dopaminergic neurones: Presynaptic mechanisms
    • Guyon A, Skrzydelsi D, Rovere C, Rostene W, Parsadaniantz SM, Nahon JL: Stromal cell-derived factor-1alpha modulation of the excitability of rat substantia nigra dopaminergic neurones: presynaptic mechanisms. J Neurochem 2006; 96: 1540-1550.
    • (2006) J Neurochem , vol.96 , pp. 1540-1550
    • Guyon, A.1    Skrzydelsi, D.2    Rovere, C.3    Rostene, W.4    Parsadaniantz, S.M.5    Nahon, J.L.6
  • 103
    • 77951248824 scopus 로고    scopus 로고
    • Intravenous administration of mesenchymal stem cells exerts therapeutic effects on parkinsonian model of rats: Focusing on neuroprotective effects of stromal cell-derived factor-1alpha
    • Wang F, Yasuhara T, Shingo T, Kameda M, Tajiri N, Yuan WJ, Kondo A, Kadota T, Baba T, Tayra JT, Kikuchi Y, Miyoshi Y, Date I: Intravenous administration of mesenchymal stem cells exerts therapeutic effects on parkinsonian model of rats: focusing on neuroprotective effects of stromal cell-derived factor-1alpha. BMC Neurosci 2010; 11: 52.
    • (2010) BMC Neurosci , vol.11 , pp. 52
    • Wang, F.1    Yasuhara, T.2    Shingo, T.3    Kameda, M.4    Tajiri, N.5    Yuan, W.J.6    Kondo, A.7    Kadota, T.8    Baba, T.9    Tayra, J.T.10    Kikuchi, Y.11    Miyoshi, Y.12    Date, I.13
  • 104
    • 78651440933 scopus 로고    scopus 로고
    • Interactions between chemokine and mu-opioid receptors: Anatomical findings and electrophysiological studies in the rat periaqueductal grey
    • Heinisch S, Palma J, Kirby LG: Interactions between chemokine and mu-opioid receptors: anatomical findings and electrophysiological studies in the rat periaqueductal grey. Brain Behav Immun 2011; 25: 360-372.
    • (2011) Brain Behav Immun , vol.25 , pp. 360-372
    • Heinisch, S.1    Palma, J.2    Kirby, L.G.3
  • 106
    • 38949105498 scopus 로고    scopus 로고
    • GTPgammaS incorporation in the rat brain: A study on mu-opioid receptors and CXCR4
    • Burbassi S, Aloyo VJ, Simansky KJ, Meucci O: GTPgammaS incorporation in the rat brain: a study on mu-opioid receptors and CXCR4. J Neuroimmune Pharmacol 2008; 3: 26-34.
    • (2008) J Neuroimmune Pharmacol , vol.3 , pp. 26-34
    • Burbassi, S.1    Aloyo, V.J.2    Simansky, K.J.3    Meucci, O.4
  • 107
    • 46649100868 scopus 로고    scopus 로고
    • Bi-directional heterologous desensitization between the major HIV-1 co-receptor CXCR4 and the kappa-opioid receptor
    • Finley MJ, Chen X, Bardi G, Davey P, Geller EB, Zhang L, Adler MW, Rogers TJ: Bi-directional heterologous desensitization between the major HIV-1 co-receptor CXCR4 and the kappa-opioid receptor. J Neuroimmunol 2008; 197: 114-123.
    • (2008) J Neuroimmunol , vol.197 , pp. 114-123
    • Finley, M.J.1    Chen, X.2    Bardi, G.3    Davey, P.4    Geller, E.B.5    Zhang, L.6    Adler, M.W.7    Rogers, T.J.8
  • 108
    • 79952697438 scopus 로고    scopus 로고
    • Analgesic efficacy of buprenorphine in the presence of high levels of SDF- 1-/CXCL12 in the brain
    • Benamar K, Palma J, Cowan A, Geller EB, Adler MW: Analgesic efficacy of buprenorphine in the presence of high levels of SDF- 1-/CXCL12 in the brain. Drug Alcohol Depend 2011; 114: 246-248.
    • (2011) Drug Alcohol Depend , vol.114 , pp. 246-248
    • Benamar, K.1    Palma, J.2    Cowan, A.3    Geller, E.B.4    Adler, M.W.5
  • 109
    • 0036679172 scopus 로고    scopus 로고
    • Heterologous desensitization of opioid receptors by chemokines inhibits chemotaxis and enhances the perception of pain
    • Szabo I, Chen XH, Xin L, Adler MW, Howard OM, Oppenheim JJ, Rogers TJ: Heterologous desensitization of opioid receptors by chemokines inhibits chemotaxis and enhances the perception of pain. Proc Natl Acad Sci USA 2002; 99: 10276-10281.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 10276-10281
    • Szabo, I.1    Chen, X.H.2    Xin, L.3    Adler, M.W.4    Howard, O.M.5    Oppenheim, J.J.6    Rogers, T.J.7
  • 110
    • 77958487299 scopus 로고    scopus 로고
    • Alterations of CXCR4 function in -opioid receptor- deficient glia
    • Burbassi S, Sengupta R, Meucci O: Alterations of CXCR4 function in -opioid receptor- deficient glia. Eur J Neurosci 2010; 32: 1278-1288.
    • (2010) Eur J Neurosci , vol.32 , pp. 1278-1288
    • Burbassi, S.1    Sengupta, R.2    Meucci, O.3
  • 111
    • 28844433347 scopus 로고    scopus 로고
    • Are chemokines the third major system in the brain?
    • Adler MW, Rogers TJ: Are chemokines the third major system in the brain? J Leukoc Biol 2005; 78: 1204-1209.
    • (2005) J Leukoc Biol , vol.78 , pp. 1204-1209
    • Adler, M.W.1    Rogers, T.J.2
  • 112
    • 42449104412 scopus 로고    scopus 로고
    • First in vivo evidence for a functional interaction between chemokine and cannabinoid systems in the brain
    • Benamar K, Geller EB, Adler MW: First in vivo evidence for a functional interaction between chemokine and cannabinoid systems in the brain. J Pharmacol Exp Ther 2008; 325: 641-645.
    • (2008) J Pharmacol Exp Ther , vol.325 , pp. 641-645
    • Benamar, K.1    Geller, E.B.2    Adler, M.W.3
  • 113
    • 70350347699 scopus 로고    scopus 로고
    • Physiological evidence for interaction between the HIV-1 co-receptor CXCR4 and the cannabinoid system in the brain
    • Benamar K, Yondorf M, Geller EB, Eisenstein TK, Adler MW: Physiological evidence for interaction between the HIV-1 co-receptor CXCR4 and the cannabinoid system in the brain. Br J Pharmacol 2009; 157: 1225-1231.
    • (2009) Br J Pharmacol , vol.157 , pp. 1225-1231
    • Benamar, K.1    Yondorf, M.2    Geller, E.B.3    Eisenstein, T.K.4    Adler, M.W.5
  • 114
    • 72049117891 scopus 로고    scopus 로고
    • SDF-1alpha/CXCL12 enhances GABA and glutamate synaptic activity at serotonin neurons in the rat dorsal raphe nucleus
    • Heinisch S, Kirby LG: SDF-1alpha/CXCL12 enhances GABA and glutamate synaptic activity at serotonin neurons in the rat dorsal raphe nucleus. Neuropharmacology 2010; 58: 501-514.
    • (2010) Neuropharmacology , vol.58 , pp. 501-514
    • Heinisch, S.1    Kirby, L.G.2
  • 115
    • 40549122731 scopus 로고    scopus 로고
    • CXCR4 receptors in the dorsal medulla: Implications for autonomic dysfunction
    • Hermann GE, Van Meter MJ, Rogers RC: CXCR4 receptors in the dorsal medulla: implications for autonomic dysfunction. Eur J Neurosci 2008; 27: 855-864.
    • (2008) Eur J Neurosci , vol.27 , pp. 855-864
    • Hermann, G.E.1    Van Meter, M.J.2    Rogers, R.C.3
  • 116
    • 23944467800 scopus 로고    scopus 로고
    • A Cxcl12-CXCR4 chemokine signaling pathway defines the initial trajectory of mammalian motor axons
    • Lieberam I, Agalliu D, Nagasawa T, Ericson J, Jessell TM: A Cxcl12-CXCR4 chemokine signaling pathway defines the initial trajectory of mammalian motor axons. Neuron 2005; 47: 667-679.
    • (2005) Neuron , vol.47 , pp. 667-679
    • Lieberam, I.1    Agalliu, D.2    Nagasawa, T.3    Ericson, J.4    Jessell, T.M.5
  • 118
    • 35349020900 scopus 로고    scopus 로고
    • Reduced CXCL12/CXCR4 results in impaired learning and is downregulated in a mouse model of Alzheimer disease
    • Parachikova A, Cotman CW: Reduced CXCL12/CXCR4 results in impaired learning and is downregulated in a mouse model of Alzheimer disease. Neurobiol Dis 2007; 28: 143-153.
    • (2007) Neurobiol Dis , vol.28 , pp. 143-153
    • Parachikova, A.1    Cotman, C.W.2
  • 119
    • 40849112965 scopus 로고    scopus 로고
    • Short-term exercise in aged Tg2576 mice alters neuroinflammation and improves cognition
    • Parachikova A, Nichol KE, Cotman CW: Short-term exercise in aged Tg2576 mice alters neuroinflammation and improves cognition. Neurobiol Dis 2008; 30: 121-129.
    • (2008) Neurobiol Dis , vol.30 , pp. 121-129
    • Parachikova, A.1    Nichol, K.E.2    Cotman, C.W.3
  • 120
    • 0037101610 scopus 로고    scopus 로고
    • A dual role for the SDF-1/CXCR4 chemokine receptor system in adult brain: Isoform-selective regulation of SDF-1 expression modulates CXCR4-dependent neuronal plasticity and cerebral leukocyte recruitment after focal ischemia
    • Stumm RK, Rummel J, Junker V, Culmsee C, Pfeiffer M, Krieglstein J, Höllt V, Schulz S: A dual role for the SDF-1/CXCR4 chemokine receptor system in adult brain: isoform-selective regulation of SDF-1 expression modulates CXCR4-dependent neuronal plasticity and cerebral leukocyte recruitment after focal ischemia. J Neurosci 2002; 22: 5865-5878.
    • (2002) J Neurosci , vol.22 , pp. 5865-5878
    • Stumm, R.K.1    Rummel, J.2    Junker, V.3    Culmsee, C.4    Pfeiffer, M.5    Krieglstein, J.6    Höllt, V.7    Schulz, S.8
  • 124
    • 33751256842 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1 and VEGF upregulate CXCR4 in glioblastoma: Implications for angiogenesis and glioma cell invasion
    • Zagzag D, Lukyanov Y, Lan L, Ali MA, Esencay M, Mendez O, Yee H, Voura EB, Newcomb EW: Hypoxia-inducible factor 1 and VEGF upregulate CXCR4 in glioblastoma: implications for angiogenesis and glioma cell invasion. Lab Invest 2006; 86: 1221-1232.
    • (2006) Lab Invest , vol.86 , pp. 1221-1232
    • Zagzag, D.1    Lukyanov, Y.2    Lan, L.3    Ali, M.A.4    Esencay, M.5    Mendez, O.6    Yee, H.7    Voura, E.B.8    Newcomb, E.W.9
  • 125
    • 0142172456 scopus 로고    scopus 로고
    • Role of chemokines in angiogenesis: CXCL12/SDF-1 and CXCR4 interaction, a key regulator of endothelial cell responses
    • Salcedo R, Oppenheim JJ: Role of chemokines in angiogenesis: CXCL12/SDF-1 and CXCR4 interaction, a key regulator of endothelial cell responses. Microcirculation 2003; 10: 359-370.
    • (2003) Microcirculation , vol.10 , pp. 359-370
    • Salcedo, R.1    Oppenheim, J.J.2
  • 127
    • 0033810455 scopus 로고    scopus 로고
    • Differential expression and responsiveness of chemokine receptors (CXCR1-3) by human microvascular endothelial cells and umbilical vein endothelial cells
    • Salcedo R, Resau JH, Halverson D, Hudson EA, Dambach M, Powell D, Wasserman K, Oppenheim JJ: Differential expression and responsiveness of chemokine receptors (CXCR1-3) by human microvascular endothelial cells and umbilical vein endothelial cells. FASEB J 2000; 14: 2055-2064.
    • (2000) FASEB J , vol.14 , pp. 2055-2064
    • Salcedo, R.1    Resau, J.H.2    Halverson, D.3    Hudson, E.A.4    Dambach, M.5    Powell, D.6    Wasserman, K.7    Oppenheim, J.J.8
  • 128
    • 0032948123 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and basic fibroblast growth factor induce expression of CXCR4 on human endothelial cells: In vivo neovascularization induced by stromal- derived factor-1alpha
    • Salcedo R, Wasserman K, Young HA, Grimm MC, Howard OM, Anver MR, Kleinman HK, Murphy WJ, Oppenheim JJ: Vascular endothelial growth factor and basic fibroblast growth factor induce expression of CXCR4 on human endothelial cells: in vivo neovascularization induced by stromal- derived factor-1alpha. Am J Pathol 1999; 154: 1125-1135.
    • (1999) Am J Pathol , vol.154 , pp. 1125-1135
    • Salcedo, R.1    Wasserman, K.2    Young, H.A.3    Grimm, M.C.4    Howard, O.M.5    Anver, M.R.6    Kleinman, H.K.7    Murphy, W.J.8    Oppenheim, J.J.9
  • 130
    • 22244470409 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1alpha and CXCR4 expression in hemangioblastoma and clear cell-renal cell carcinoma: Von Hippel-Lindau loss-offunction induces expression of a ligand and its receptor
    • Zagzag D, Krishnamachary B, Yee H, Okuyama H, Chiriboga L, Ali MA, Melamed J, Semenza GL: Stromal cell-derived factor-1alpha and CXCR4 expression in hemangioblastoma and clear cell-renal cell carcinoma: von Hippel-Lindau loss-offunction induces expression of a ligand and its receptor. Cancer Res 2005; 65: 6178- 6188.
    • (2005) Cancer Res , vol.65 , pp. 6178-6188
    • Zagzag, D.1    Krishnamachary, B.2    Yee, H.3    Okuyama, H.4    Chiriboga, L.5    Ali, M.A.6    Melamed, J.7    Semenza, G.L.8
  • 131
    • 33749262441 scopus 로고    scopus 로고
    • Irradiation and hypoxia promote homing of haematopoietic progenitor cells towards gliomas by TGF-beta-dependent HIF-1alpha-mediated induction of CXCL12
    • Tabatabai G, Frank B, Möhle R, Weller M, Wick W: Irradiation and hypoxia promote homing of haematopoietic progenitor cells towards gliomas by TGF-beta-dependent HIF-1alpha-mediated induction of CXCL12. Brain 2006; 129: 2426-2435.
    • (2006) Brain , vol.129 , pp. 2426-2435
    • Tabatabai, G.1    Frank, B.2    Möhle, R.3    Weller, M.4    Wick, W.5
  • 135
    • 47249112916 scopus 로고    scopus 로고
    • SDF 1-alpha (CXCL12) triggers glutamate exocytosis from astrocytes on a millisecond time scale: Imaging analysis at the single- vesicle level with TIRF microscopy
    • Cali C, Marchaland J, Regazzi R, Bezzi P: SDF 1-alpha (CXCL12) triggers glutamate exocytosis from astrocytes on a millisecond time scale: imaging analysis at the single- vesicle level with TIRF microscopy. J Neuroimmunol 2008; 198: 82-91.
    • (2008) J Neuroimmunol , vol.198 , pp. 82-91
    • Cali, C.1    Marchaland, J.2    Regazzi, R.3    Bezzi, P.4
  • 136
    • 0035865331 scopus 로고    scopus 로고
    • CXC chemokine receptor expression and function in human astroglioma cells
    • Oh JW, Drabik K, Kutsch O, Choi C, Tousson A, Benveniste EN: CXC chemokine receptor expression and function in human astroglioma cells. J Immunol 2001; 166: 2695-2704.
    • (2001) J Immunol , vol.166 , pp. 2695-2704
    • Oh, J.W.1    Drabik, K.2    Kutsch, O.3    Choi, C.4    Tousson, A.5    Benveniste, E.N.6
  • 137
  • 138
    • 0142172456 scopus 로고    scopus 로고
    • Role of chemokines in angiogenesis: CXCL12/SDF-1 and CXCR4 interaction, a key regulator of endothelial cell responses
    • Salcedo R, Oppenheim JJ: Role of chemokines in angiogenesis: CXCL12/SDF-1 and CXCR4 interaction, a key regulator of endothelial cell responses. Microcirculation 2003; 10: 359-370.
    • (2003) Microcirculation , vol.10 , pp. 359-370
    • Salcedo, R.1    Oppenheim, J.J.2
  • 140
    • 0035808593 scopus 로고    scopus 로고
    • TNFalpha down-regulates CXCR4 expression in primary murine astrocytes
    • Han Y, Wang J, He T, Ransohoff RM: TNFalpha down-regulates CXCR4 expression in primary murine astrocytes. Brain Res 2001; 888: 1-10.
    • (2001) Brain Res , vol.888 , pp. 1-10
    • Han, Y.1    Wang, J.2    He, T.3    Ransohoff, R.M.4
  • 142
    • 68949119874 scopus 로고    scopus 로고
    • IL-1R signaling within the central nervous system regulates CXCL12 expression at the blood-brain barrier and disease severity during experimental autoimmune encephalomyelitis
    • McCandless EE, Budde M, Lees JR, Dorsey D, Lyng E, Klein RS: IL-1R signaling within the central nervous system regulates CXCL12 expression at the blood-brain barrier and disease severity during experimental autoimmune encephalomyelitis. J Immunol 2009; 183: 613-620.
    • (2009) J Immunol , vol.183 , pp. 613-620
    • McCandless, E.E.1    Budde, M.2    Lees, J.R.3    Dorsey, D.4    Lyng, E.5    Klein, R.S.6
  • 143
    • 0037131268 scopus 로고    scopus 로고
    • Interleukin-6 and cAMP induce stromal cell-derived factor-1 chemotaxis in astroglia by up-regulating CXCR4 cell surface expression. Implications for brain inflammation
    • Odemis V, Moepps B, Gierschik P, Engele J: Interleukin-6 and cAMP induce stromal cell-derived factor-1 chemotaxis in astroglia by up-regulating CXCR4 cell surface expression. Implications for brain inflammation. J Biol Chem 2002; 277: 39801- 39808.
    • (2002) J Biol Chem , vol.277 , pp. 39801-39808
    • Odemis, V.1    Moepps, B.2    Gierschik, P.3    Engele, J.4
  • 145
    • 34547094132 scopus 로고    scopus 로고
    • The anticancer compound Nordy inhibits CXCR4- mediated production of IL-8 and VEGF by malignant human glioma cells
    • Ping YF, Yao XH, Chen JH, Liu H, Chen DL, Zhou XD, Wang JM, Bian XW: The anticancer compound Nordy inhibits CXCR4- mediated production of IL-8 and VEGF by malignant human glioma cells. J Neurooncol 2007; 84: 21-29.
    • (2007) J Neurooncol , vol.84 , pp. 21-29
    • Ping, Y.F.1    Yao, X.H.2    Chen, J.H.3    Liu, H.4    Chen, D.L.5    Zhou, X.D.6    Wang, J.M.7    Bian, X.W.8
  • 146
    • 23644456320 scopus 로고    scopus 로고
    • C3a expressed in the central nervous system protects against LPS-induced shock
    • Boos L, Szalai AJ, Barnum SR: C3a expressed in the central nervous system protects against LPS-induced shock. Neurosci Lett 2005; 387: 68-71.
    • (2005) Neurosci Lett , vol.387 , pp. 68-71
    • Boos, L.1    Szalai, A.J.2    Barnum, S.R.3
  • 147
    • 72849120050 scopus 로고    scopus 로고
    • Complement-derived anaphylatoxin C3a regulates in vitro differentiation and migration of neural progenitor cells
    • Shinjyo N, Stahlberg A, Dragunow M, Pekny M, Pekna M: Complement-derived anaphylatoxin C3a regulates in vitro differentiation and migration of neural progenitor cells. Stem Cells 2009; 27: 2824-2832.
    • (2009) Stem Cells , vol.27 , pp. 2824-2832
    • Shinjyo, N.1    Stahlberg, A.2    Dragunow, M.3    Pekny, M.4    Pekna, M.5
  • 148
    • 27944455701 scopus 로고    scopus 로고
    • The chemokine stromal cell derived factor-1 (CXCL12) promotes glioma invasiveness through MT2-matrix metalloproteinase
    • Zhang J, Sarkar S, Yong VW: The chemokine stromal cell derived factor-1 (CXCL12) promotes glioma invasiveness through MT2-matrix metalloproteinase. Carcinogenesis 2005; 26: 2069-2077.
    • (2005) Carcinogenesis , vol.26 , pp. 2069-2077
    • Zhang, J.1    Sarkar, S.2    Yong, V.W.3
  • 149
    • 38149098378 scopus 로고    scopus 로고
    • LRRC4 inhibits human glioblastoma cells proliferation, invasion, and proMMP-2 activation by reducing SDF-1 alpha/CXCR4-mediated ERK1/2 and Akt signaling pathways
    • Wu M, Chen Q, Li D, Li X, Li X, Huang C, Tang Y, Zhou Y, Wang D, Tang K, Cao L, Shen S, Li G: LRRC4 inhibits human glioblastoma cells proliferation, invasion, and proMMP-2 activation by reducing SDF-1 alpha/CXCR4-mediated ERK1/2 and Akt signaling pathways. J Cell Biochem 2008; 103: 245-255.
    • (2008) J Cell Biochem , vol.103 , pp. 245-255
    • Wu, M.1    Chen, Q.2    Li, D.3    Li, X.4    Li, X.5    Huang, C.6    Tang, Y.7    Zhou, Y.8    Wang, D.9    Tang, K.10    Cao, L.11    Shen, S.12    Li, G.13
  • 151
    • 0037114177 scopus 로고    scopus 로고
    • Cell surface peptidase CD26/dipeptidylpeptidase IV regulates CXCL12/ stromal cell-derived factor-1 alpha-mediated chemotaxis of human cord blood CD34+ progenitor cells
    • Christopherson KW 2nd, Hangoc G, Broxmeyer HE: Cell surface peptidase CD26/dipeptidylpeptidase IV regulates CXCL12/ stromal cell-derived factor-1 alpha-mediated chemotaxis of human cord blood CD34+ progenitor cells. J Immunol 2002; 169: 7000-7008.
    • (2002) J Immunol , vol.169 , pp. 7000-7008
    • Christopherson II, K.W.1    Hangoc, G.2    Broxmeyer, H.E.3
  • 152
    • 45849116582 scopus 로고    scopus 로고
    • Modulation of substance P signaling by dipeptidyl peptidase-IV enzymatic activity in human glioma cell lines
    • Busek P, Stremenová J, Krepela E, Sedo A: Modulation of substance P signaling by dipeptidyl peptidase-IV enzymatic activity in human glioma cell lines. Physiol Res 2008; 57: 443-449.
    • (2008) Physiol Res , vol.57 , pp. 443-449
    • Busek, P.1    Stremenová, J.2    Krepela, E.3    Sedo, A.4
  • 153
    • 34247254468 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor prevents the nigrostriatal degeneration induced by human immunodeficiency virus-1 glycoprotein in vivo
    • Nosheny RL, Ahmed F, Yakovlev A, Meyer EM, Ren K, Tessarollo L, Mocchetti I: Brain-derived neurotrophic factor prevents the nigrostriatal degeneration induced by human immunodeficiency virus-1 glycoprotein in vivo. Eur J Neurosci 2007; 25: 2275-2284.
    • (2007) Eur J Neurosci , vol.25 , pp. 2275-2284
    • Nosheny, R.L.1    Ahmed, F.2    Yakovlev, A.3    Meyer, E.M.4    Ren, K.5    Tessarollo, L.6    Mocchetti, I.7
  • 154
    • 48949098705 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor modulates expression of chemokine receptors in the brain
    • Ahmed F, Tessarollo L, Thiele C, Mocchetti I: Brain-derived neurotrophic factor modulates expression of chemokine receptors in the brain. Brain Res 2008; 1227: 1-11.
    • (2008) Brain Res , vol.1227 , pp. 1-11
    • Ahmed, F.1    Tessarollo, L.2    Thiele, C.3    Mocchetti, I.4
  • 155
    • 77954383548 scopus 로고    scopus 로고
    • HGF upregulates CXCR4 expression in gliomas via NF-kappaB: Implications for glioma cell migration
    • Esencay M, Newcomb EW, Zagzag D: HGF upregulates CXCR4 expression in gliomas via NF-kappaB: implications for glioma cell migration. J Neurooncol 2010; 99: 33-40.
    • (2010) J Neurooncol , vol.99 , pp. 33-40
    • Esencay, M.1    Newcomb, E.W.2    Zagzag, D.3
  • 156
    • 67650266687 scopus 로고    scopus 로고
    • CXCR4 and SDF-1 production are stimulated by hepatocyte growth factor and promote glioma cell invasion
    • Tu H, Zhou Z, Liang Q, Li Z, Li D, Qing J, Wang H, Zhang L: CXCR4 and SDF-1 production are stimulated by hepatocyte growth factor and promote glioma cell invasion. Onkologie 2009; 32: 331-336.
    • (2009) Onkologie , vol.32 , pp. 331-336
    • Tu, H.1    Zhou, Z.2    Liang, Q.3    Li, Z.4    Li, D.5    Qing, J.6    Wang, H.7    Zhang, L.8
  • 157
    • 77951222418 scopus 로고    scopus 로고
    • Interactions between chemokines: Regulation of fractalkine/CX- 3CL1 homeostasis by SDF/CXCL12 in cortical neurons
    • Cook A, Hippensteel R, Shimizu S, Nicolai J, Fatatis A, Meucci O: Interactions between chemokines: regulation of fractalkine/CX- 3CL1 homeostasis by SDF/CXCL12 in cortical neurons. J Biol Chem 2010; 285: 10563- 10571.
    • (2010) J Biol Chem , vol.285 , pp. 10563-10571
    • Cook, A.1    Hippensteel, R.2    Shimizu, S.3    Nicolai, J.4    Fatatis, A.5    Meucci, O.6
  • 158
    • 77950630894 scopus 로고    scopus 로고
    • Munoz- Fernández MA: Nuclear factor-kappaB activation regulates cyclooxygenase-2 induction in human astrocytes in response to CXCL12: Role in neuronal toxicity
    • Alvarez S, Blanco A, Fresno M, Munoz- Fernández MA: Nuclear factor-kappaB activation regulates cyclooxygenase-2 induction in human astrocytes in response to CXCL12: role in neuronal toxicity. J Neurochem 2010; 113: 772-783.
    • (2010) J Neurochem , vol.113 , pp. 772-783
    • Alvarez, S.1    Blanco, A.2    Fresno, M.3
  • 159
    • 34447535456 scopus 로고    scopus 로고
    • HIV-1 envelope glycoprotein induces cyclooxygenase-2 expression in astrocytoma cells through a nuclear factor-kappaB-dependent mechanism
    • Alvarez S, Serramía MJ, Fresno M, Munoz- Fernández MA: HIV-1 envelope glycoprotein induces cyclooxygenase-2 expression in astrocytoma cells through a nuclear factor-kappaB-dependent mechanism. Neuromolecular Med 2007; 9: 179-193.
    • (2007) Neuromolecular Med , vol.9 , pp. 179-193
    • Alvarez, S.1    Serramía, M.J.2    Fresno, M.3    Munoz-Fernández, M.A.4
  • 160
    • 69949175962 scopus 로고    scopus 로고
    • Shp2 acts downstream of SDF-1alpha/CXCR4 in guiding granule cell migration during cerebellar development
    • Hagihara K, Zhang EE, Ke YH, Liu G, Liu JJ, Rao Y, Feng GS: Shp2 acts downstream of SDF-1alpha/CXCR4 in guiding granule cell migration during cerebellar development. Dev Biol 2009; 334: 276-284.
    • (2009) Dev Biol , vol.334 , pp. 276-284
    • Hagihara, K.1    Zhang, E.E.2    Ke, Y.H.3    Liu, G.4    Liu, J.J.5    Rao, Y.6    Feng, G.S.7
  • 161
    • 65249157074 scopus 로고    scopus 로고
    • CXCL12- mediated induction of plasminogen activator inhibitor-1 expression in human CXCR4 positive astroglioma cells
    • Oh JW, Olman M, Benveniste EN: CXCL12- mediated induction of plasminogen activator inhibitor-1 expression in human CXCR4 positive astroglioma cells. Biol Pharm Bull 2009; 32: 573-577.
    • (2009) Biol Pharm Bull , vol.32 , pp. 573-577
    • Oh, J.W.1    Olman, M.2    Benveniste, E.N.3
  • 164
    • 0037147223 scopus 로고    scopus 로고
    • CXCR4 is a major chemokine receptor on glioma cells and mediates their survival
    • Zhou Y, Larsen PH, Hao C, Yong VW: CXCR4 is a major chemokine receptor on glioma cells and mediates their survival. J Biol Chem 2002; 277: 49481-49487.
    • (2002) J Biol Chem , vol.277 , pp. 49481-49487
    • Zhou, Y.1    Larsen, P.H.2    Hao, C.3    Yong, V.W.4
  • 165
    • 0035010217 scopus 로고    scopus 로고
    • Stromal cellderived factor-1alpha induces astrocyte proliferation through the activation of extracellular signal-regulated kinases 1/2 pathway
    • Bajetto A, Barbero S, Bonavia R, Piccioli P, Pirani P, Florio T, Schettini G: Stromal cellderived factor-1alpha induces astrocyte proliferation through the activation of extracellular signal-regulated kinases 1/2 pathway. J Neurochem 2001; 77: 1226-1236.
    • (2001) J Neurochem , vol.77 , pp. 1226-1236
    • Bajetto, A.1    Barbero, S.2    Bonavia, R.3    Piccioli, P.4    Pirani, P.5    Florio, T.6    Schettini, G.7
  • 166
    • 0033959236 scopus 로고    scopus 로고
    • Differential signalling of the chemokine receptor CXCR4 by stromal cell-derived factor 1 and the HIV glycoprotein in rat neurons and astrocytes
    • Lazarini F, Casanova P, Tham TN, De Clercq E, Arenzana-Seisdedos F, Baleux F, Dubois-Dalcq M: Differential signalling of the chemokine receptor CXCR4 by stromal cell-derived factor 1 and the HIV glycoprotein in rat neurons and astrocytes. Eur J Neurosci 2000; 12: 117-125.
    • (2000) Eur J Neurosci , vol.12 , pp. 117-125
    • Lazarini, F.1    Casanova, P.2    Tham, T.N.3    De Clercq, E.4    Arenzana-Seisdedos, F.5    Baleux, F.6    Dubois-Dalcq, M.7
  • 168
    • 0037309854 scopus 로고    scopus 로고
    • Signalling pathways involved in the chemotactic activity of CXCL12 in cultured rat cerebellar neurons and CHP100 neuroepithelioma cells
    • Floridi F, Trettel F, Di Bartolomeo S, Ciotti MT, Limatola C: Signalling pathways involved in the chemotactic activity of CXCL12 in cultured rat cerebellar neurons and CHP100 neuroepithelioma cells. J Neuroimmunol 2003; 135: 38-46.
    • (2003) J Neuroimmunol , vol.135 , pp. 38-46
    • Floridi, F.1    Trettel, F.2    Di Bartolomeo, S.3    Ciotti, M.T.4    Limatola, C.5
  • 169
    • 0037418610 scopus 로고    scopus 로고
    • Chemokines and their receptors in the CNS: Expression of CXCL12/SDF-1 and CXCR4 and their role in astrocyte proliferation
    • Bonavia R, Bajetto A, Barbero S, Pirani P, Florio T, Schettini G: Chemokines and their receptors in the CNS: expression of CXCL12/SDF-1 and CXCR4 and their role in astrocyte proliferation. Toxicol Lett 2003; 139: 181-189.
    • (2003) Toxicol Lett , vol.139 , pp. 181-189
    • Bonavia, R.1    Bajetto, A.2    Barbero, S.3    Pirani, P.4    Florio, T.5    Schettini, G.6
  • 171
    • 24644501261 scopus 로고    scopus 로고
    • The chemokine receptor CXCR4 is regulated byDNA methylation in pancreatic cancer
    • Sato N, Matsubayashi H, Fukushima N, Goggins M: The chemokine receptor CXCR4 is regulated byDNA methylation in pancreatic cancer. Cancer Biol Ther 2005; 4: 70-76.
    • (2005) Cancer Biol Ther , vol.4 , pp. 70-76
    • Sato, N.1    Matsubayashi, H.2    Fukushima, N.3    Goggins, M.4
  • 172
    • 64049109279 scopus 로고    scopus 로고
    • Differential expression of stromal cell-derived factor 1 in human brain microvascular endothelial cells and pericytes involves histone modifications
    • Seo J, Kim YO, Jo I: Differential expression of stromal cell-derived factor 1 in human brain microvascular endothelial cells and pericytes involves histone modifications. Biochem Biophys Res Commun 2009; 382: 519-524.
    • (2009) Biochem Biophys Res Commun , vol.382 , pp. 519-524
    • Seo, J.1    Kim, Y.O.2    Jo, I.3
  • 173
    • 0037447318 scopus 로고    scopus 로고
    • Stromal cell-derived factor 1alpha stimulates human glioblastoma cell growth through the activation of both extracellular signal-regulated kinases 1/2 and Akt
    • Barbero S, Bonavia R, Bajetto A, Porcile C, Pirani P, Ravetti JL, Zona GL, Spaziante R, Florio T, Schettini G: Stromal cell-derived factor 1alpha stimulates human glioblastoma cell growth through the activation of both extracellular signal-regulated kinases 1/2 and Akt. Cancer Res 2003; 63: 1969- 1974.
    • (2003) Cancer Res , vol.63 , pp. 1969-1974
    • Barbero, S.1    Bonavia, R.2    Bajetto, A.3    Porcile, C.4    Pirani, P.5    Ravetti, J.L.6    Zona, G.L.7    Spaziante, R.8    Florio, T.9    Schettini, G.10
  • 175
    • 48849112000 scopus 로고    scopus 로고
    • Functional response to SDF1 alpha through over-expression of CXCR4 on adult subventricular zone progenitor cells
    • Liu XS, Chopp M, Santra M, Hozeska-Solgot A, Zhang RL, Wang L, Teng H, Lu M, Zhang ZG: Functional response to SDF1 alpha through over-expression of CXCR4 on adult subventricular zone progenitor cells. Brain Res 2008; 1226: 18-26.
    • (2008) Brain Res , vol.1226 , pp. 18-26
    • Liu, X.S.1    Chopp, M.2    Santra, M.3    Hozeska-Solgot, A.4    Zhang, R.L.5    Wang, L.6    Teng, H.7    Lu, M.8    Zhang, Z.G.9
  • 176
  • 177
    • 77951600246 scopus 로고    scopus 로고
    • The chemokine SDF-1/CXCL12 contributes to the 'homing' of umbilical cord blood cells to a hypoxic-ischemic lesion in the rat brain
    • Rosenkranz K, Kumbruch S, Lebermann K, Marschner K, Jensen A, Dermietzel R, Meier C: The chemokine SDF-1/CXCL12 contributes to the 'homing' of umbilical cord blood cells to a hypoxic-ischemic lesion in the rat brain. J Neurosci Res 2010; 88: 1223- 1233.
    • (2010) J Neurosci Res , vol.88 , pp. 1223-1233
    • Rosenkranz, K.1    Kumbruch, S.2    Lebermann, K.3    Marschner, K.4    Jensen, A.5    Dermietzel, R.6    Meier, C.7
  • 178
    • 33646598696 scopus 로고    scopus 로고
    • CXCR4 expression mediates glioma cell invasiveness
    • Ehtesham M, Winston JA, Kabos P, Thompson RC: CXCR4 expression mediates glioma cell invasiveness. Oncogene 2006; 25: 2801-2806.
    • (2006) Oncogene , vol.25 , pp. 2801-2806
    • Ehtesham, M.1    Winston, J.A.2    Kabos, P.3    Thompson, R.C.4
  • 179
    • 77949715989 scopus 로고    scopus 로고
    • Resisting arrest: A switch from angiogenesis to vasculogenesis in recurrent malignant gliomas
    • Greenfield JP, Cobb WS, Lyden D: Resisting arrest: a switch from angiogenesis to vasculogenesis in recurrent malignant gliomas. J Clin Invest 2010; 120: 663-667.
    • (2010) J Clin Invest , vol.120 , pp. 663-667
    • Greenfield, J.P.1    Cobb, W.S.2    Lyden, D.3
  • 180
    • 77949697909 scopus 로고    scopus 로고
    • Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice
    • Kioi M, Vogel H, Schultz G, Hoffman RM, Harsh GR, Brown JM: Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice. J Clin Invest 2010; 120: 694- 705.
    • (2010) J Clin Invest , vol.120 , pp. 694-705
    • Kioi, M.1    Vogel, H.2    Schultz, G.3    Hoffman, R.M.4    Harsh, G.R.5    Brown, J.M.6
  • 181
    • 75949130595 scopus 로고    scopus 로고
    • Glioblastoma and endothelial cells crosstalk, mediated by SDF-1, enhances tumour invasion and endothelial proliferation by increasing expression of cathepsins B, S, and MMP-9
    • Kenig S, Alonso MB, Mueller MM, Lah TT: Glioblastoma and endothelial cells crosstalk, mediated by SDF-1, enhances tumour invasion and endothelial proliferation by increasing expression of cathepsins B, S, and MMP-9. Cancer Lett 2010; 289: 53-61.
    • (2010) Cancer Lett , vol.289 , pp. 53-61
    • Kenig, S.1    Alonso, M.B.2    Mueller, M.M.3    Lah, T.T.4
  • 182
    • 33749499603 scopus 로고    scopus 로고
    • Tumor stromal-derived factor-recruits vascular progenitors to mitotic neovasculature, where microenvironment influences their differentiated phenotypes
    • Aghi M, Cohen KS, Klein RJ, Scadden DT, Chiocca EA: Tumor stromal-derived factor-recruits vascular progenitors to mitotic neovasculature, where microenvironment influences their differentiated phenotypes. Cancer Res 2006; 66: 9054-9064.
    • (2006) Cancer Res , vol.66 , pp. 9054-9064
    • Aghi, M.1    Cohen, K.S.2    Klein, R.J.3    Scadden, D.T.4    Chiocca, E.A.5
  • 184
    • 67650033114 scopus 로고    scopus 로고
    • Immunoimaging of CXCR4 expression in brain tumor xenografts using SPECT/CT
    • Nimmagadda S, Pullambhatla M, Pomper MG: Immunoimaging of CXCR4 expression in brain tumor xenografts using SPECT/CT. J Nucl Med 2009; 50: 1124-1130.
    • (2009) J Nucl Med , vol.50 , pp. 1124-1130
    • Nimmagadda, S.1    Pullambhatla, M.2    Pomper, M.G.3
  • 188
    • 33845312983 scopus 로고    scopus 로고
    • CXCR4 inhibition synergizes with cytotoxic chemotherapy in gliomas
    • Redjal N, Chan JA, Segal RA, Kung AL: CXCR4 inhibition synergizes with cytotoxic chemotherapy in gliomas. Clin Cancer Res 2006; 12: 6765-6771.
    • (2006) Clin Cancer Res , vol.12 , pp. 6765-6771
    • Redjal, N.1    Chan, J.A.2    Segal, R.A.3    Kung, A.L.4
  • 190
    • 77958544067 scopus 로고    scopus 로고
    • Profound blockage of CXCR4 signaling at multiple points using the synergy between plerixafor, mirtazapine, and clotrimazole as a new glioblastoma treatment adjunct
    • Kast RE: Profound blockage of CXCR4 signaling at multiple points using the synergy between plerixafor, mirtazapine, and clotrimazole as a new glioblastoma treatment adjunct. Turk Neurosurg 2010; 20: 425-429.
    • (2010) Turk Neurosurg , vol.20 , pp. 425-429
    • Kast, R.E.1
  • 193
    • 60849126162 scopus 로고    scopus 로고
    • Characterization and application of two novel monoclonal antibodies against human CXCR4: Cell proliferation and migration regulation for glioma cell line in vitro by CXCR4/SDF-1alpha signal
    • Cheng Z, Zhou S, Wang X, Xie F, Wu H, Liu G, Wang Q, Chen Y, Hu Y, Lu B, Zhang X: Characterization and application of two novel monoclonal antibodies against human CXCR4: cell proliferation and migration regulation for glioma cell line in vitro by CXCR4/SDF-1alpha signal. Hybridoma (Larchmt) 2009; 28: 33-41.
    • (2009) Hybridoma (Larchmt) , vol.28 , pp. 33-41
    • Cheng, Z.1    Zhou, S.2    Wang, X.3    Xie, F.4    Wu, H.5    Liu, G.6    Wang, Q.7    Chen, Y.8    Hu, Y.9    Lu, B.10    Zhang, X.11
  • 197
    • 2442687810 scopus 로고    scopus 로고
    • Glioma tropic neural stem cells consist of astrocytic precursors and their migratory capacity is mediated by CXCR4
    • Ehtesham M, Yuan X, Kabos P, Chung NH, Liu G, Akasaki Y, Black KL, Yu JS: Glioma tropic neural stem cells consist of astrocytic precursors and their migratory capacity is mediated by CXCR4. Neoplasia 2004; 6: 287-293.
    • (2004) Neoplasia , vol.6 , pp. 287-293
    • Ehtesham, M.1    Yuan, X.2    Kabos, P.3    Chung, N.H.4    Liu, G.5    Akasaki, Y.6    Black, K.L.7    Yu, J.S.8
  • 199
    • 79958107497 scopus 로고    scopus 로고
    • Targeting SDF-1/CXCR4 to inhibit tumour vasculature for treatment of glioblastomas
    • Tseng D, Vasquez-Medrano DA, Brown JM: Targeting SDF-1/CXCR4 to inhibit tumour vasculature for treatment of glioblastomas. Br J Cancer 2011; 104: 1805-1809.
    • (2011) Br J Cancer , vol.104 , pp. 1805-1809
    • Tseng, D.1    Vasquez-Medrano, D.A.2    Brown, J.M.3
  • 201
    • 58149332686 scopus 로고    scopus 로고
    • Translating an antagonist of chemokine receptor CXCR4: From bench to bedside
    • Wong D, Korz W: Translating an antagonist of chemokine receptor CXCR4: from bench to bedside. Clin Cancer Res 2008; 14: 7975- 7980.
    • (2008) Clin Cancer Res , vol.14 , pp. 7975-7980
    • Wong, D.1    Korz, W.2
  • 202
    • 84858235813 scopus 로고    scopus 로고
    • CXCL12 mediates apoptosis resistance in rat C6 glioma cells
    • Hattermann K, Mentlein R, Held-Feindt J: CXCL12 mediates apoptosis resistance in rat C6 glioma cells. Oncol Rep 2012; 27: 1348-1352.
    • (2012) Oncol Rep , vol.27 , pp. 1348-1352
    • Hattermann, K.1    Mentlein, R.2    Held-Feindt, J.3
  • 203


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