The peptidomimetic CXCR4 antagonist TC14012 recruits β-arrestin to CXCR7: Roles of receptor domains

Journal of Biological Chemistry

Volumn 285, Issue 49, 2010, Pages 37939-37943

  Gravel, Stéphanie ^a,b   Malouf, Camille ^a,b   Boulais, Philip E ^c   Berchiche, Yamina A ^a,b   Oishi, Shinya ^d   Fujii, Nobutaka ^d   Leduc, Richard ^c   Sinnett, Daniel ^a,c   Heveker, Nikolaus ^a,b  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b UNIVERSITY OF MONTREAL   (Canada)

^c UNIVERSITY OF SHERBROOKE   (Canada)

^d KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; BINDING ENERGY; CHEMICAL ACTIVATION; ENERGY TRANSFER;

ACTIVATION MECHANISMS; AGONISTIC ACTIVITY; BIOLUMINESCENCE RESONANCE ENERGY TRANSFER; CHEMOKINE LIGANDS; CHEMOKINE RECEPTORS; HETEROTRIMERIC G PROTEINS; LIGAND-BINDING SURFACES; TRANS-MEMBRANE DOMAINS;

LIGANDS;

BETA ARRESTIN; CHEMOKINE RECEPTOR CXCR4 ANTAGONIST; CHEMOKINE RECEPTOR CXCR7; MITOGEN ACTIVATED PROTEIN KINASE 1; PEPTIDOMIMETIC AGENT; PLERIXAFOR; TC 14012; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; BIOLUMINESCENCE RESONANCE ENERGY TRANSFER; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DRUG ACTIVITY; ENZYME ACTIVATION; GLIOMA CELL; HUMAN; HUMAN CELL; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION;

EID: 78649673542     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.C110.147470     Document Type: Article

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