CXCR4 and CXCL12 expression is increased in the nigro-striatal system of Parkinson's disease

Neurotoxicity Research

Volumn 16, Issue 3, 2009, Pages 318-328

  Shimoji, Mika ^a   Pagan, Fernando ^b   Healton, Edward B ^b   Mocchetti, Italo ^a  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^b GEORGETOWN UNIVERSITY HOSPITAL   (United States)

Author keywords

CCL5 RANTES; Chemokines; CXCL12 SDF 1 ; Dopamine neurons; Human brains; Microglia; MPTP; Striatum; Substantia nigra

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; CHEMOKINE RECEPTOR CXCR4; STROMAL CELL DERIVED FACTOR 1;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; CELL ACTIVATION; CELL LOSS; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOREACTIVITY; MALE; MICROGLIA; MOUSE; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SUBSTANTIA NIGRA; UPREGULATION;

ANALYSIS OF VARIANCE; ANIMALS; CHEMOKINE CXCL12; CORPUS STRIATUM; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; HUMANS; MICE; MICROGLIA; MPTP POISONING; PARKINSON DISEASE; PHOSPHOPYRUVATE HYDRATASE; POSTMORTEM CHANGES; RECEPTORS, CXCR4; SUBSTANTIA NIGRA; TIME FACTORS; TYROSINE 3-MONOOXYGENASE;

ANIMALIA; MUS; RODENTIA;

EID: 70349909667     PISSN: 10298428     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12640-009-9076-3     Document Type: Article

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