CXCR4 and SDF-1 production are stimulated by hepatocyte growth factor and promote glioma cell invasion

Onkologie

Volumn 32, Issue 6, 2009, Pages 331-336

  Tu, Hanjun ^a,b   Zhou, Zhangming ^b   Liang, Qingle ^b   Li, Zhiqiang ^c   Li, Dongsheng ^b   Qing, Jun ^b   Wang, Hui ^b   Zhang, Li ^b  

^a RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

^b HUBEI UNIVERSITY OF MEDICINE   (China)

^c WUHAN UNIVERSITY   (China)

Author keywords

CXCR4; Glioma; HGF; Invasion; Proliferation; SDF 1

Indexed keywords

BROXURIDINE; CHEMOKINE RECEPTOR CXCR4; DNA MARKER; K 252A; MESSENGER RNA; PLERIXAFOR; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; SMALL INTERFERING RNA; STROMAL CELL DERIVED FACTOR 1;

ARTICLE; CANCER CELL CULTURE; CANCER INVASION; CELL INVASION; CELL PROLIFERATION; CELL STRAIN U251; CONTROLLED STUDY; DNA SYNTHESIS; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE ACTIVATED CELL SORTER; GLIOMA CELL; HUMAN; HUMAN CELL; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; PROTEIN FUNCTION;

CELL PROLIFERATION; CHEMOKINE CXCL12; GLIOMA; HEPATOCYTE GROWTH FACTOR; HUMANS; NEOPLASM INVASIVENESS; RECEPTORS, CXCR4; SIGNAL TRANSDUCTION;

EID: 67650266687     PISSN: 0378584X     EISSN: None     Source Type: Journal    
DOI: 10.1159/000216352     Document Type: Article

References (20)

1. Scott JN, Rewcastle NB, Brasher PM, Fulton D, MacKinnon JA, Hamilton M, Cairncross JG, Forsyth P: Which glioblastoma multiforme patient will become a long-term survivor? A population-based study. Ann Neurol 1999;46:183-188.
2. Abounader R, Laterra J: Scatter factor/hepatocyte growth factor in brain tumor growth and angiogenesis. Neuro Oncol 2005;7:436-451.
3. Eckerich C, Zapf S, Fillbrandt R, Loges S, Westphal M, Lamszus K: Hypoxia can induce c-Met expression in glioma cells and enhance SF/HGF-induced cell migration. Int J Cancer 2007;12:276-283.
4. Uchinokura S, Miyata S, Fukushima T, Itoh H, Nakano S, Wakisaka S, Kataoka H: Role of hepatocyte growth factor activator (HGF activator) in invasive growth of human glioblastoma cells in vivo. Int J Cancer 2006;118:583-592.
5. Na I, Scheibenbogen C, Adam C, Stroux A, Keil-holz U, Ghadjar P, Busse A, Thiel E, Coupland SE: Nuclear CXCR4 is correlated with lymph node metastasis in lung cancer. Onkologie 2006;29(suppl 3):9.
6. Bajetto A, Barbieri F, Dorcaratto A, Barbero S, Daga A, Porcile C, Ravetti JL, Zona G, Spaziante R, Corte G, Schettini G, Florio T: Expression of CXC chemokine receptors 1-5 and their ligands in human glioma tissues: role of CXCR4 and SDF1 in glioma cell proliferation and migration. Neurochem Int 2006;49:423-432.
7. Walles T, Weimer M, Linke K, Michaelis J, Mertsching H: The potential of bioartificial tissues in oncology research and treatment. Onkologie 2007;30: 388-394.
8. Gassmann P, Enns A, Haier J: Role of tumor cell adhesion and migration in organ-specific metastasis formation. Onkologie 2004;27:577-582.
9. Hong X, Jiang F, Kalkanis SN: SDF-1 and CXCR4 are up-regulated by VEGF and contribute to glioma cell invasion. Cancer Lett 2006;236:39-45.
10. Roccisana J, Reddy V, Vasavada RC, Gonzalez-Pertusa JA, Magnuson MA, Garcia-Ocaña A: Targeted inactivation of hepatocyte growth factor receptor c-met in (beta)-cells leads to defective insulin secretion and GLUT-2 downregulation without alteration of (beta)-cell mass. Diabetes 2005;54:2090-2102.
11. Zhang J, Sarkar S, Yong VW: The chemokine stromal cell derived factor-1 (CXCL12) promotes glioma invasiveness through MT2-matrix metalloproteinase. Carcinogenesis 2005;26:2069-2077.
12. Yang L, Jackson E, Woerner BM, Perry A, Piwnica-Worms D, Rubin JB: Blocking CXCR4-mediated cyclic AMP suppression inhibits brain tumor growth in vivo. Cancer Res 2007;67:651-658.
13. Libura J, Drukala J, Majka M, Tomescu O, Navenot JM, Kucia M, Marquez L, Peiper SC, Barr FG, Janowska-Wieczorek A, Ratajczak MZ: CXCR4-SDF-1 signaling is active in rhabdomyosarcoma cells and regulates locomotion, chemotaxis, and adhesion. Blood 2002;100:2597-2606.
14. Morotti A, Mila S, Accornero P, Tagliabue E, Ponzetto C: K252a inhibits the oncogenic properties of Met, the HGF receptor. Oncogene 2002;21: 4885-4893.
15. Nakashiro K, Hara S, Shinohara Y, Oyasu M, Kawamata H, Shintani S, Hamakawa H, Oyasu R: Phenotypic switch from paracrine to autocrine role of hepatocyte growth factor in an androgen-independent human prostatic carcinoma cell line, CWR22R. Am J Pathol 2004;165:533-540.
16. Livak KJ, Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001;25:402-408.
17. Chen Y, Stamatoyannopoulos G, Song CZ: Downregulation of CXCR4 by inducible small interfering RNA inhibits breast cancer cell invasion in vitro. Cancer Res 2003;63:4801-4804.
18. Kajiyama H, Shibata K, Terauchi M, Ino K, Nawa A, Kikkawa F: Involvement of SDF-1alpha/ CXCR4 axis in the enhanced peritoneal metastasis of epithelial ovarian carcinoma. Int J Cancer 2008;122:91-99.
19. Miura Y, Kozuki Y, Yagasaki K: Potentiation of invasive activity of hepatoma cells by reactive oxygen species is mediated by autocrine/paracrine loop of hepatocyte growth factor. Biochem Biophys Res Commun 2003;305:160-165.
20. Hu B, Guo P, Bar-Joseph I, Jarzynka MJ, Bogler O, Mikkelsen T, Hirose T, Nishikawa R, Cheng SY: Neuropilin-1 promotes human glioma progression through potentiating the activity of the HGF/SF autocrine pathway. Oncogene 2007;26:5577-5586.