Brain-derived neurotrophic factor modulates expression of chemokine receptors in the brain

Brain Research

Volumn 1227, Issue , 2008, Pages 1-11

  Ahmed, Farid ^a   Tessarollo, Lino ^b   Thiele, Carol ^c   Mocchetti, Italo ^a  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

BDNF; CCR5; CXCR4; gp120; HIV dementia; TrkB

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; CELL SURFACE PROTEIN; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; GLYCOPROTEIN GP 120; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN; BRAIN CORTEX; CONTROLLED STUDY; CORPUS STRIATUM; DEMENTIA; ENZYME ACTIVITY; FEMALE; HETEROZYGOTE; HIPPOCAMPUS; HIV ASSOCIATED DEMENTIA; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOREACTIVITY; INTERNALIZATION; MALE; NERVE CELL; NEUROBLASTOMA CELL; NEUROPATHOLOGY; NEUROPROTECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR UPREGULATION;

ANIMALS; BRAIN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL LINE, TUMOR; CEREBRAL CORTEX; CORPUS STRIATUM; CYCLOPHILINS; FLUORESCENT ANTIBODY TECHNIQUE, DIRECT; GLIAL FIBRILLARY ACIDIC PROTEIN; HETEROZYGOTE; HIPPOCAMPUS; HUMANS; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURONS; RECEPTOR, TRKB; RECEPTORS, CCR5; RECEPTORS, CHEMOKINE; RECEPTORS, CXCR3; RECEPTORS, CXCR4; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RIBOSOMAL PROTEINS; RNA, MESSENGER;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS 1; MUS;

EID: 48949098705     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2008.05.086     Document Type: Article

References (53)

1. Bachis A., Major E.O., and Mocchetti I. Brain-derived neurotrophic factor inhibits human immunodeficiency virus-1/gp120-mediated cerebellar granule cell death by preventing gp120 internalization. J. Neurosci. 23 (2003) 5715-5722
2. Bachis A., and Mocchetti I. Brain-derived neurotrophic factor is neuroprotective against human immunodeficiency virus-1 envelope proteins. Ann. N. Y. Acad. Sci. 1053 (2005) 247-257
3. Bachis A., Aden S.A., Nosheny R.L., Andrews P.M., and Mocchetti I. Axonal transport of Human Immunodeficiency Virus Type 1 envelope glycoprotein 120 is found in association with neuronal apoptosis. J. Neurosci. 26 (2006) 6771-6780
4. Bagri A., Gurney T., He X., Zou Y.R., Littman D.R., Tessier-Lavigne M., and Pleasure S.J. The chemokine SDF1 regulates migration of dentate granule cells. Development 129 (2002) 4249-4260
5. Banisadr G., Fontanges P., Haour F., Kitabgi P., Rostene W., and Parsadaniantz S.M. Neuroanatomical distribution of CXCR4 in adult rat brain and its localization in cholinergic and dopaminergic neurons. Eur. J. Neurosci. 16 (2002) 1661-1671
6. Bansal A.K., Mactutus C.F., Nath A., Maragos W., Hauser K.F., and Booze R.M. Neurotoxicity of HIV-1 proteins gp120 and Tat in the rat striatum. Brain. Res. 879 (2000) 42-49
7. Bardi G., Sengupta R., Khan M.Z., Patel J.P., and Meucci O. Human immunodeficiency virus gp120-induced apoptosis of human neuroblastoma cells in the absence of CXCR4 internalization. J. Neurovirol. 12 (2006) 211-218
8. Berson J.F., Long D., Doranz B.J., Rucker J., Jirik F.R., and Doms R.W. A seven-transmembrane domain receptor involved in fusion and entry of T-cell-tropic human immunodeficiency virus type 1 strains. J. Virol. 70 (1996) 6288-6295
9. Biard-Piechaczyk M., Robert-Hebmann V., Richard V., Roland J., Hipskind R.A., and Devaux C. Caspase-dependent apoptosis of cells expressing the chemokine receptor CXCR4 is induced by cell membrane-associated human immunodeficiency virus type 1 envelope glycoprotein (gp120). Virology 268 (2000) 329-344
10. Chao M.V. Neurotrophins and their receptors: a convergence point for many signalling pathways. Nat. Rev. Neurosci. 4 (2003) 299-309
11. Dorsey S.G., Renn C.L., Carim-Todd L., Barrick C.A., Bambrick L., Krueger B.K., Ward C.W., and Tessarollo L. In vivo restoration of physiological levels of truncated TrkB.T1 receptor rescues neuronal cell death in a trisomic mouse model. Neuron 51 (2006) 21-28
12. Everall I.P., Hansen L.A., and Masliah E. The shifting patterns of HIV encephalitis neuropathology. Neurotox. Res. 8 (2005) 51-61
13. Feng Y., Broder C.C., Kennedy P.E., and Berger E.A. HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Science 10 (1996) 872-877
14. Fryer R.H., Kaplan D.R., Feinstein S.C., Radeke M.J., Grayson D.R., and Kromer L.F. Developmental and mature expression of full-length and truncated TrkB receptors in the rat forebrain. J. Comp. Neurol. 374 (1996) 21-40
15. Givalois L., Arancibia S., Alonso G., and Tapia-Arancibia L. Expression of brain-derived neurotrophic factor and its receptors in the median eminence cells with sensitivity to stress. Endocrinol 145 (2004) 4737-4747
16. Gray F., Adle-Biassette H., Chretien F., Lorin de la Grandmaison G., Force G., and Keohane C. Neuropathology and neurodegeneration in human immunodeficiency virus infection. Pathogenesis of HIV-induced lesions of the brain, correlations with HIV-associated disorders and modifications according to treatments. Clin. Neuropathol. 20 (2001) 146-155
17. He J., Chen Y., Farzan M., Choe H., Ohagen A., Gartner S., Busciglio J., Yang X., Hofmann W., Newman W., Mackay C.R., Sodroski J., and Gabuzda D. CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia. Nature 385 (1997) 645-649
18. Hesselgesser J., Taub D., Baskar P., Greenberg M., Hoxie J., Kolson D.L., and Horuk R. Neuronal apoptosis induced by HIV-1 gp120 and the chemokine SDF-1 alpha is mediated by the chemokine receptor CXCR4. Curr. Biol. 8 (1998) 595-598
19. James H.J., Sharer L.R., Zhang Q., Wang H.G., Epstein L.G., Reed J.C., and Gelbard H.A. Expression of caspase-3 in brains from paediatric patients with HIV-1 encephalitis. Neuropathol. Appl. Neurobiol. 25 (1999) 380-386
20. Kaplan D.R., Matsumoto K., Lucarelli E., and Thiele C.J. Induction of TrkB by retinoic acid mediates biologic responsiveness to BDNF and differentiation of human neuroblastoma cells. Neuron 11 (1993) 321-331
21. Kaul M., and Lipton S.A. Chemokines and activated macrophages in HIV gp120-induced neuronal apoptosis. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 8212-8216
22. Kim C.J., Matsuo T., Lee K.-H., and Thiele C.J. Up-regulation of insulin-like growth factor-II expression is a feature of TrkA but not TrkB activation in SH-SY5Y neuroblastoma cells. Am. J. Pathol. 155 (1999) 1661-1670
23. Klein R.S., Williams K.C., Alvarez-Hernandez X., Westmoreland S., Force T., Lackner A.A., and Luster A.D. Chemokine receptor expression and signaling in macaque and human fetal neurons and astrocytes: implications for the neuropathogenesis of AIDS. J. Immunol. 163 (1999) 1636-1646
24. Kruman I.I., Nath A., and Mattson M.P. HIV-1 protein Tat induces apoptosis of hippocampal neurons by a mechanism involving caspase activation, calcium overload, and oxidative stress. Exp. Neurol. 154 (1998) 276-288
25. Lavi E., Strizki J.M., Ulrich A.M., Zhang W., Fu L., Wang Q., O'Connor M., Hoxie J.A., and Gonzalez-Scarano F. CXCR-4 (Fusin), a co-receptor for the type 1 human immunodeficiency virus (HIV-1), is expressed in the human brain in a variety of cell types, including microglia and neurons. Am. J. Pathol. 151 (1997) 1035-1042
26. Lazarini F., Casanova P., Tham T.N., De Clercq E., Arenzana-Seisdedos F., Baleux F., and Dubois-Dalcq M. Differential signalling of the chemokine receptor CXCR4 by stromal cell-derived factor 1 and the HIV glycoprotein in rat neurons and astrocytes. Eur. J. Neurosci. 12 (2000) 117-125
27. Lazarini F., Tham T.N., Casanova P., Arenzana-Seisdedos F., and Dubois-Dalcq M. Role of the alpha-chemokine stromal cell-derived factor (SDF-1) in the developing and mature central nervous system. Glia 42 (2003) 139-148
28. Lledo P.M., Alonso M., and Grubb M.S. Adult neurogenesis and functional plasticity in neuronal circuits. Nat. Rev. Neurosci. 7 (2006) 179-193
29. Lu M., Grove E.A., and Miller R.J. Abnormal development of the hippocampal dentate gyrus in mice lacking the CXCR4 chemokine receptor. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 7090-7095
30. Lyons W.E., Mamounas L.A., Ricaurte G.A., Coppola V., Reid S.W., Bora S.H., Wihler C., Koliatsos V.E., and Tessarollo L. Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 15239-15244
31. Ma Q., Jones D., Borghesani P.R., Segal R.A., Nagasawa T., Kishimoto T., Bronson R.T., and Springer T.A. Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 9448-9453
32. Masliah E., DeTeresa R.M., Mallory M.E., and Hansen L.A. Changes in pathological findings at autopsy in AIDS cases for the last 15 years. AIDS 14 (2000) 69-74
33. McArthur J.C. HIV dementia: an evolving disease. J. Neuroimmunol. 157 (2004) 3-10
34. Meucci O., Fatatis A., Simen A.A., Bushell T.J., Gray P.W., and Miller R.J. Chemokines regulate hippocampal neuronal signaling and gp120 neurotoxicity. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 14500-14505
35. Miller F.D., and Kaplan D.R. Signaling mechanisms underlying dendrite formation. Curr. Opin. Neurobiol. 13 (2003) 391-398
36. Miller R.J., and Tran P.B. Chemokinetics. Neuron 47 (2005) 621
37. Mocchetti I., and Bachis A. Brain-derived neurotrophic factor activation of TrkB protects neurons from HIV-1/gp120-induced cell death. Crit. Rev. Neurobiol. 16 (2004) 51-57
38. Moore J.P., Kitchen S.G., Pugach P., and Zack J.A. The CCR5 and CXCR4 coreceptors-central to understanding the transmission and pathogenesis of human immunodeficiency virus type 1 infection. AIDS. Res. Hum. Retrovir. 20 (2004) 111-126
39. Nosheny R.L., Bachis A., Acquas E., and Mocchetti I. Human immunodeficiency virus type 1 glycoprotein gp120 reduces the levels of brain-derived neurotrophic factor in vivo: potential implication for neuronal cell death. Eur. J. Neurosci. 20 (2004) 2857-2864
40. Nosheny R.L., Amhed F., Yakovlev A.G., Meyer E.M., Ren K., Tessarollo L., and Mocchetti I. Brain-derived neurotrophic factor prevents the nigrostriatal degeneration induced by human immunodeficiency virus-1 glycoprotein 120 in vivo. Eur. J. Neurosci 25 (2007) 2275-2284
41. Ohira K., and Hayashi M. Expression of TrkB subtypes in the adult monkey cerebellar cortex. J. Chem. Neuroanatomy. 25 (2003) 175-183
42. Sanders V.J., Everall I.P., Johnson R.W., and Masliah E. Fibroblast growth factor modulates HIV coreceptor CXCR4 expression by neural cells. HNRC Group. J. Neurosci. Res. 59 (2000) 671-679
43. Schmidt H.D., and Duman R.S. The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior. Behav. Pharmacol. 18 (2007) 391-418
44. Signoret N., Hewlett L., Wavre S., Pelchen-Matthews A., Oppermann M., and Marsh M. Agonist-induced endocytosis of CC chemokine receptor 5 is clathrin dependent. Mol. Biol. Cell. 16 (2005) 902-917
45. Stumm R.K., Zhou C., Ara T., Lazarini F., Dubois-Dalcq M., Nagasawa T., Hollt V., and Schulz S. CXCR4 regulates interneuron migration in the developing neocortex. J. Neurosci 23 (2003) 5123-5130
46. Tarasova N.I., Stauber R.H., and Michejda C.J. Spontaneous and ligand-induced trafficking of CXC-chemokine receptor 4. J. Biol. Chem. 273 (1998) 15883-15886
47. Toggas S.M., Masliah E., Rockenstein E.M., Rall G.F., Abraham C.R., and Mucke L. Central nervous system damage produced by expression of the HIV-1 coat protein gp120 in transgenic mice. Nature 367 (1994) 188-193
48. Torres-Munoz J.E., Van Waveren C., Keegan M.G., Bookman R.J., and Petito C.K. Gene expression profiles in microdissected neurons from human hippocampal subregions. Mol. Brain. Res. 127 (2004) 105-114
49. Tran P.B., Banisadr G., Ren D., Chenn A., and Miller R.J. Chemokine receptor expression by neural progenitor cells in neurogenic regions of mouse brain. J. Comp. Neurol 500 (2007) 1007-1034
50. van der Meer P., Ulrich A.M., Gonzalez-Scarano F., and Lavi E. Immunohistochemical analysis of CCR2, CCR3, CCR5, and CXCR4 in the human brain: potential mechanisms for HIV dementia. Exp. Mol. Pathol. 69 (2000) 192-201
51. Vergote D., Butler G.S., Ooms M., Cox J.H., Silva C., Hollenberg M.D., Jhamandas J.H., Overall C.M., and Power C. Proteolytic processing of SDF-1{alpha} reveals a change in receptor specificity mediating HIV-associated neurodegeneration. Proc. Natl. Acad. Sci 103 (2006) 19182-19187
52. Westmoreland S.V., Alvarez X., deBakker C., Aye P., Wilson M.L., Williams K.C., and Lackner A.A. Developmental expression patterns of CCR5 and CXCR4 in the rhesus macaque brain. J. Neuroimmunol. 122 (2002) 146-158
53. Zheng J., Thylin M.R., Ghorpade A., Xiong H., Persidsky Y., Cotter R., Niemann D., Che M., Zeng Y.C., Gelbard H.A., Shepard R.B., Swartz J.M., and Gendelman H.E. Intracellular CXCR4 signaling, neuronal apoptosis and neuropathogenic mechanisms of HIV-1-associated dementia. J. Neuroimmunol. 98 (1999) 185-200