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Volumn 9, Issue 1, 2010, Pages

CXCL12/CXCR4 promotes motility and proliferation of glioma cells

Author keywords

Apoptosis; Brain tumor; Chemotaxis; CXCL12; CXCR4; Glioblastoma; Proliferation

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; F ACTIN; PHOSPHATIDYLINOSITOL 3 KINASE; PLERIXAFOR; PROTEIN KINASE B; STROMAL CELL DERIVED FACTOR 1;

EID: 75749086811     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (59)

References (34)
  • 1
    • 33845208787 scopus 로고    scopus 로고
    • Interindividual differences in anticancer drug cytotoxicity in primary glioblastoma cells
    • Pédeboscq S, Azou B, Liguoro D, Pometan J, Cambar. Interindividual differences in anticancer drug cytotoxicity in primary glioblastoma cells. Exp Toxicol Pathol 2007; 58:247-53.
    • (2007) Exp Toxicol Pathol , vol.58 , pp. 247-253
    • Pédeboscq, S.1    Azou, B.2    Liguoro, D.3    Pometan, J.4    Cambar5
  • 2
    • 48249125791 scopus 로고    scopus 로고
    • Malignant gliomas in adults
    • Wen P, Kesari S. Malignant gliomas in adults. N Engl J Med 2008; 359:492-507.
    • (2008) N Engl J Med , vol.359 , pp. 492-507
    • Wen, P.1    Kesari, S.2
  • 4
    • 58149290094 scopus 로고    scopus 로고
    • CXCR4 expression is elevated in glioblastoma multiforme and correlates with an increase in intensity and extent of peritumoral T2-weighted magnetic resonance imaging signal abnormalities
    • Stevenson CB, Ehtesham M, McMillan KM, Valadez JG, Edgeworth ML, Price RR, et al. CXCR4 expression is elevated in glioblastoma multiforme and correlates with an increase in intensity and extent of peritumoral T2-weighted magnetic resonance imaging signal abnormalities. Neurosur 2008; 63:560-70.
    • (2008) Neurosur , vol.63 , pp. 560-570
    • Stevenson, C.B.1    Ehtesham, M.2    McMillan, K.M.3    Valadez, J.G.4    Edgeworth, M.L.5    Price, R.R.6
  • 5
    • 58249100053 scopus 로고    scopus 로고
    • CXCR4 antagonists: Targeting the microenvironment in leukemia and other cancers
    • Burge J, Peled A. CXCR4 antagonists: targeting the microenvironment in leukemia and other cancers. Leukemia 2009; 23:43-52.
    • (2009) Leukemia , vol.23 , pp. 43-52
    • Burge, J.1    Peled, A.2
  • 6
    • 0037447318 scopus 로고    scopus 로고
    • Stromal Cell-derived Factor-1α stimulates human glioblastoma cell growth through the activation of both extracellular signal-regulated kinases 1/2 and Akt
    • Barbero S, Bonavia R, Bajetto A, Porcile C, Pirani P, Ravetti JL, et al. Stromal Cell-derived Factor-1α stimulates human glioblastoma cell growth through the activation of both extracellular signal-regulated kinases 1/2 and Akt. Cancer Res 2003; 63:1969-74.
    • (2003) Cancer Res , vol.63 , pp. 1969-1974
    • Barbero, S.1    Bonavia, R.2    Bajetto, A.3    Porcile, C.4    Pirani, P.5    Ravetti, J.L.6
  • 7
    • 0037147223 scopus 로고    scopus 로고
    • CXCR4 is a major chemokine receptor on glioma cells and mediates their survival
    • Zhou Y, Larsen P, Hao C, Yong V. CXCR4 is a major chemokine receptor on glioma cells and mediates their survival. J Biol Chem 2002; 277:49481-7.
    • (2002) J Biol Chem , vol.277 , pp. 49481-49487
    • Zhou, Y.1    Larsen, P.2    Hao, C.3    Yong, V.4
  • 8
    • 60349085081 scopus 로고    scopus 로고
    • The Chemokine Receptors CXCR4 and CXCR3 in cancer
    • Fulton A. The Chemokine Receptors CXCR4 and CXCR3 in cancer. Cur Oncol Rep 2009; 11:125-31.
    • (2009) Cur Oncol Rep , vol.11 , pp. 125-131
    • Fulton, A.1
  • 9
    • 17144410313 scopus 로고    scopus 로고
    • Akt activation, but not extracellular signal-regulated kinase activation, is required for SDF-1alpha/CXCR4-mediated migration of epitheloid carcinoma cells
    • Peng SB, Peek V, Zhai Y, Paul DC, Lou Q, Xia X, et al. Akt activation, but not extracellular signal-regulated kinase activation, is required for SDF-1alpha/CXCR4-mediated migration of epitheloid carcinoma cells. Mol Cancer Res 2005; 3:227-36.
    • (2005) Mol Cancer Res , vol.3 , pp. 227-236
    • Peng, S.B.1    Peek, V.2    Zhai, Y.3    Paul, D.C.4    Lou, Q.5    Xia, X.6
  • 10
    • 33750294009 scopus 로고    scopus 로고
    • The pleiotropic effects of the SDF-1-CXCR4 axis in organogenesis, regeneration and tumorigenesis
    • Ratajczak MZ, Zuba-Surma E, Kucia M, Reca R, Wojakowski W, Ratajczak J. The pleiotropic effects of the SDF-1-CXCR4 axis in organogenesis, regeneration and tumorigenesis. Leukemia 2006; 20:1915-24.
    • (2006) Leukemia , vol.20 , pp. 1915-1924
    • Ratajczak, M.Z.1    Zuba-Surma, E.2    Kucia, M.3    Reca, R.4    Wojakowski, W.5    Ratajczak, J.6
  • 11
    • 33947393053 scopus 로고    scopus 로고
    • Regulation of CXCR4 signaling. BBA
    • Busillo JM, Benovic JL. Regulation of CXCR4 signaling. BBA 2007; 1768:952-63.
    • (2007) , vol.1768 , pp. 952-963
    • Busillo, J.M.1    Benovic, J.L.2
  • 12
    • 0344823964 scopus 로고    scopus 로고
    • A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors
    • Rubin JB, Kung AL, Klein RS, Chan JA, Sun Y, Schmidt K, et al. A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors. PNAS 2003; 100:13513-8.
    • (2003) PNAS , vol.100 , pp. 13513-13518
    • Rubin, J.B.1    Kung, A.L.2    Klein, R.S.3    Chan, J.A.4    Sun, Y.5    Schmidt, K.6
  • 14
    • 33845312983 scopus 로고    scopus 로고
    • CXCR4 inhibition synergizes with cytotoxic chemotherapy in gliomas
    • Redjal N, Chan JA, Segal RA, Kung AL. CXCR4 inhibition synergizes with cytotoxic chemotherapy in gliomas. Clin Cancer Res 2006; 12:6765-71.
    • (2006) Clin Cancer Res , vol.12 , pp. 6765-6771
    • Redjal, N.1    Chan, J.A.2    Segal, R.A.3    Kung, A.L.4
  • 16
    • 0033959917 scopus 로고    scopus 로고
    • Identification and localization of the cytokine SDF1 and its receptor, CXC chemokine receptor 4, to regions of necrosis and angiogenesis in human glioblastoma
    • Rempel SA, Dudas S, Ge S, Gutierrez JA. Identification and localization of the cytokine SDF1 and its receptor, CXC chemokine receptor 4, to regions of necrosis and angiogenesis in human glioblastoma. Clin Cancer Res 2000; 6:102-11.
    • (2000) Clin Cancer Res , vol.6 , pp. 102-111
    • Rempel, S.A.1    Dudas, S.2    Ge, S.3    Gutierrez, J.A.4
  • 17
    • 33344464945 scopus 로고    scopus 로고
    • CXCR4: A key receptor in the crosstalk between tumor cells and their microenvironment
    • Burger J, Kipps T. CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment. Blood 2006; 107:1761-7.
    • (2006) Blood , vol.107 , pp. 1761-1767
    • Burger, J.1    Kipps, T.2
  • 18
    • 39549123001 scopus 로고    scopus 로고
    • Differential modulation of CXCR4 and CD40 protein levels by skin sensitizers and irritants in the FSDC cell line
    • Neves B, Cruz M, Francisco V, Gonçalo M, Figueiredo A, Duarte C, et al. Differential modulation of CXCR4 and CD40 protein levels by skin sensitizers and irritants in the FSDC cell line. Toxicol Lett 2008; 177:74-82.
    • (2008) Toxicol Lett , vol.177 , pp. 74-82
    • Neves, B.1    Cruz, M.2    Francisco, V.3    Gonçalo, M.4    Figueiredo, A.5    Duarte, C.6
  • 19
    • 34347218991 scopus 로고    scopus 로고
    • In vitro scratch assay: A convenient and inexpensive method for analysis of cell migration in vitro
    • Liang C Park A, Guan J. In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro. Nat Protoc 2007; 2:329-33.
    • (2007) Nat Protoc , vol.2 , pp. 329-333
    • Liang, C.1    Park, A.2    Guan, J.3
  • 20
    • 38649132548 scopus 로고    scopus 로고
    • Anti-apoptosis mechanisms in malignant gliomas
    • Ziegler DS, Kung AL, Kieran MW. Anti-apoptosis mechanisms in malignant gliomas. J Clin Oncol 2008; 20:493-500.
    • (2008) J Clin Oncol , vol.20 , pp. 493-500
    • Ziegler, D.S.1    Kung, A.L.2    Kieran, M.W.3
  • 21
    • 34247848682 scopus 로고    scopus 로고
    • Preferential expression of chemokine receptor CXCR4 by highly malignant human gliomas and its association with poor patient survival
    • Bian XW, Yang SX, Chen JH, Ping YF, Zhou XD, Wang QL, et al. Preferential expression of chemokine receptor CXCR4 by highly malignant human gliomas and its association with poor patient survival. Neurosurg 2007; 61:570-9.
    • (2007) Neurosurg , vol.61 , pp. 570-579
    • Bian, X.W.1    Yang, S.X.2    Chen, J.H.3    Ping, Y.F.4    Zhou, X.D.5    Wang, Q.L.6
  • 24
    • 33746685587 scopus 로고    scopus 로고
    • Characterization of the molecular pharmacology of AMD3100: A specific antagonist of the G-protein coupled chemokine receptor, CXCR4
    • Fricker SP, Anastassov V, Cox J, Darkes MC, Grujic O, Idzan SR, et al. Characterization of the molecular pharmacology of AMD3100: a specific antagonist of the G-protein coupled chemokine receptor, CXCR4. Biochem Pharmacol 2006; 72:588-96.
    • (2006) Biochem Pharmacol , vol.72 , pp. 588-596
    • Fricker, S.P.1    Anastassov, V.2    Cox, J.3    Darkes, M.C.4    Grujic, O.5    Idzan, S.R.6
  • 25
    • 0038681342 scopus 로고    scopus 로고
    • The bicyclam AMD3100 story
    • De Clercq E. The bicyclam AMD3100 story. Nat Rev Drug Discov 2003; 2:581-7.
    • (2003) Nat Rev Drug Discov , vol.2 , pp. 581-587
    • De Clercq, E.1
  • 27
    • 33645458005 scopus 로고    scopus 로고
    • Possible regulation of migration of intrahepatic cholangiocarcinoma cells by interaction of CXCR4 expressed in carcinoma cells with tumor necrosis factoralpha and stromal-derived factor-1 released in stroma
    • Ohira S, Sasaki M, Harada K, Sato Y, Zen Y, Isse K, et al. Possible regulation of migration of intrahepatic cholangiocarcinoma cells by interaction of CXCR4 expressed in carcinoma cells with tumor necrosis factoralpha and stromal-derived factor-1 released in stroma. Am J Pathol 2006; 168:1155-68.
    • (2006) Am J Pathol , vol.168 , pp. 1155-1168
    • Ohira, S.1    Sasaki, M.2    Harada, K.3    Sato, Y.4    Zen, Y.5    Isse, K.6
  • 28
    • 8544223594 scopus 로고    scopus 로고
    • Increased survival, proliferation and migration in metastatic human pancreatic tumor cells expressing functional CXCR4
    • Marchesi F, Monti P, Leone BE, Zerbi A, Vecchi A, Piemonti L, et al. Increased survival, proliferation and migration in metastatic human pancreatic tumor cells expressing functional CXCR4. Cancer Res 2004; 64:8420-7.
    • (2004) Cancer Res , vol.64 , pp. 8420-8427
    • Marchesi, F.1    Monti, P.2    Leone, B.E.3    Zerbi, A.4    Vecchi, A.5    Piemonti, L.6
  • 29
    • 23044472971 scopus 로고    scopus 로고
    • CXCL12/stromal cell-derived factor-1alpha transactivates HER2-neu in breast cancer cells by a novel pathway involving Src kinase activation
    • Cabioglu N, Summy J, Miller C, Parikh NU, Sahin AA, Tuzlali S, et al. CXCL12/stromal cell-derived factor-1alpha transactivates HER2-neu in breast cancer cells by a novel pathway involving Src kinase activation. Cancer Res 2005; 65:6493-7.
    • (2005) Cancer Res , vol.65 , pp. 6493-6497
    • Cabioglu, N.1    Summy, J.2    Miller, C.3    Parikh, N.U.4    Sahin, A.A.5    Tuzlali, S.6
  • 31
    • 44949249877 scopus 로고    scopus 로고
    • Cdk5-mediated regulation of the PIKE-A-Akt pathway and glioblastoma cell invasion
    • Ren Liu R, Bo Tian B, Gearing M, Hunter S, Ye K, Mao Y. Cdk5-mediated regulation of the PIKE-A-Akt pathway and glioblastoma cell invasion. PNAS 2008; 27:7570-5.
    • (2008) PNAS , vol.27 , pp. 7570-7575
    • Ren Liu, R.1    Bo Tian, B.2    Gearing, M.3    Hunter, S.4    Ye, K.5    Mao, Y.6
  • 32
    • 23744481199 scopus 로고    scopus 로고
    • Activation of chemokine receptor CXCR4 in malignant glioma cells promotes the production of vascular endothelial growth factor
    • Yang S, Chen J, Jiang X, Wang Q, Chen Z, Zhao W, et al. Activation of chemokine receptor CXCR4 in malignant glioma cells promotes the production of vascular endothelial growth factor. Biochem Biophys Res Com 2005; 335:523-8.
    • (2005) Biochem Biophys Res Com , vol.335 , pp. 523-528
    • Yang, S.1    Chen, J.2    Jiang, X.3    Wang, Q.4    Chen, Z.5    Zhao, W.6
  • 33
    • 1542345587 scopus 로고    scopus 로고
    • Regulation of cell cycle proteins by chemokine receptors: A novel pathway in human immunodeficiency virus neuropathogenesis?
    • Brandimarti R, Khan M, Fatatis A, Meucci O. Regulation of cell cycle proteins by chemokine receptors: A novel pathway in human immunodeficiency virus neuropathogenesis? J NeuroVirol 2004; 10:1-5.
    • (2004) J NeuroVirol , vol.10 , pp. 1-5
    • Brandimarti, R.1    Khan, M.2    Fatatis, A.3    Meucci, O.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.