메뉴 건너뛰기




Volumn 3, Issue 12, 2008, Pages 1379-1383

The CXCR4/SDF-1 chemokine receptor axis: A new target therapeutic for non-small cell lung cancer

Author keywords

Chemokines; CXCR4; Metastasis; Migration; Non small cell lung cancer; SDF 1

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR4 ANTAGONIST; CTCE 9908; GRANULOCYTE COLONY STIMULATING FACTOR; NEUTRALIZING ANTIBODY; PLERIXAFOR; STROMAL CELL DERIVED FACTOR 1; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT;

EID: 61449451621     PISSN: 15560864     EISSN: 15561380     Source Type: Journal    
DOI: 10.1097/JTO.0b013e31818dda9d     Document Type: Article
Times cited : (60)

References (65)
  • 1
    • 0034144269 scopus 로고    scopus 로고
    • Chemokines: A new classification system and their role in immunity
    • Zlotnik A, Yoshie O. Chemokines: a new classification system and their role in immunity. Immunity 2000;12:121-127.
    • (2000) Immunity , vol.12 , pp. 121-127
    • Zlotnik, A.1    Yoshie, O.2
  • 2
    • 0037418256 scopus 로고    scopus 로고
    • Chemokine signaling: Rules of attraction
    • Schier AF. Chemokine signaling: rules of attraction. Curr Biol 2003;13: R192-R194.
    • (2003) Curr Biol , vol.13
    • Schier, A.F.1
  • 3
    • 0034092634 scopus 로고    scopus 로고
    • International union of pharmacology. XXII. Nomenclature for chemokine receptors
    • Murphy PM, Baggiolini M, Charo IF, et al. International union of pharmacology. XXII. Nomenclature for chemokine receptors. Pharmacol Rev 2000;52:145-176.
    • (2000) Pharmacol Rev , vol.52 , pp. 145-176
    • Murphy, P.M.1    Baggiolini, M.2    Charo, I.F.3
  • 4
    • 0028052968 scopus 로고
    • Interleukin-8 and related chemotactic cytokines-CXC and CC chemokines
    • Baggiolini M, Dewald B, Moser B. Interleukin-8 and related chemotactic cytokines-CXC and CC chemokines. Adv Immunol 1994;55:97-179.
    • (1994) Adv Immunol , vol.55 , pp. 97-179
    • Baggiolini, M.1    Dewald, B.2    Moser, B.3
  • 5
    • 0028136769 scopus 로고
    • Chemokines, inflammation and the immune system
    • Taub DD, Oppenheim JJ. Chemokines, inflammation and the immune system. Ther Immunol 1994;1:229-246.
    • (1994) Ther Immunol , vol.1 , pp. 229-246
    • Taub, D.D.1    Oppenheim, J.J.2
  • 6
    • 15844419153 scopus 로고    scopus 로고
    • Identification of a major co-receptor for primary isolates of HIV-1
    • Deng H, Liu R, Ellmeier W, et al. Identification of a major co-receptor for primary isolates of HIV-1. Nature 1996;38:661-666.
    • (1996) Nature , vol.38 , pp. 661-666
    • Deng, H.1    Liu, R.2    Ellmeier, W.3
  • 7
    • 0030002637 scopus 로고    scopus 로고
    • HIV-1 entry cofactor: Functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor
    • Feng Y, Broder CC, Kennedy PE, Berger EA. HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Science 1996;272:872-877.
    • (1996) Science , vol.272 , pp. 872-877
    • Feng, Y.1    Broder, C.C.2    Kennedy, P.E.3    Berger, E.A.4
  • 8
    • 0028012561 scopus 로고
    • Cloning of a human seven-transmembrane domain receptor, LESTR, that is highly expressed in leukocytes
    • Loetscher M, Geiser T, O'Reilly T, Zwahlen R, Baggiolini M, Moser B. Cloning of a human seven-transmembrane domain receptor, LESTR, that is highly expressed in leukocytes. J Biol Chem 1994;269:232-237.
    • (1994) J Biol Chem , vol.269 , pp. 232-237
    • Loetscher, M.1    Geiser, T.2    O'Reilly, T.3    Zwahlen, R.4    Baggiolini, M.5    Moser, B.6
  • 9
    • 0034080318 scopus 로고    scopus 로고
    • The biology of chemokines and their receptors
    • Rossi D, Zlotnik A. The biology of chemokines and their receptors. Annu Rev Immunol 2000;18:217-242.
    • (2000) Annu Rev Immunol , vol.18 , pp. 217-242
    • Rossi, D.1    Zlotnik, A.2
  • 10
    • 0028324454 scopus 로고
    • Molecular cloning and structure of a pre-B-cell growth-stimulating factor
    • Nagasawa T, Kikutani H, Kishimoto T. Molecular cloning and structure of a pre-B-cell growth-stimulating factor. Proc Natl Acad Sci USA 1994;91:2305-2309.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 2305-2309
    • Nagasawa, T.1    Kikutani, H.2    Kishimoto, T.3
  • 11
    • 0029833943 scopus 로고    scopus 로고
    • A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)
    • Bleul CC, Fuhlbrigge RC, Casasnovas JM, Aiuti A, Springer TA. A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1). J Exp Med 1996;184:1101-1109.
    • (1996) J Exp Med , vol.184 , pp. 1101-1109
    • Bleul, C.C.1    Fuhlbrigge, R.C.2    Casasnovas, J.M.3    Aiuti, A.4    Springer, T.A.5
  • 12
    • 0032507962 scopus 로고    scopus 로고
    • Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development
    • Zou YR, Kottmann AH, Kuroda M, Taniuchi I, Littman DR. Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. Nature 1998;393:595-599.
    • (1998) Nature , vol.393 , pp. 595-599
    • Zou, Y.R.1    Kottmann, A.H.2    Kuroda, M.3    Taniuchi, I.4    Littman, D.R.5
  • 13
    • 0038024047 scopus 로고    scopus 로고
    • Expression of functional CXCR4 by muscle satellite cells and secretion of SDF-1 by musclederived fibroblasts is associated with the presence of both muscle progenitors in bone marrow and hematopoietic stem/progenitor cells in muscles
    • Ratajczak MZ, Majka M, Kucia M, et al. Expression of functional CXCR4 by muscle satellite cells and secretion of SDF-1 by musclederived fibroblasts is associated with the presence of both muscle progenitors in bone marrow and hematopoietic stem/progenitor cells in muscles. Stem Cells 2003;21:363-371.
    • (2003) Stem Cells , vol.21 , pp. 363-371
    • Ratajczak, M.Z.1    Majka, M.2    Kucia, M.3
  • 14
    • 0029758113 scopus 로고    scopus 로고
    • Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1
    • Nagasawa T, Hirota S, Tachibana K, et al. Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1. Nature 1996;382:635-638.
    • (1996) Nature , vol.382 , pp. 635-638
    • Nagasawa, T.1    Hirota, S.2    Tachibana, K.3
  • 15
    • 0036746634 scopus 로고    scopus 로고
    • The chemokine SDF1 regulates migration of dentate granule cells
    • Bagri A, Gurney T, He X, et al. The chemokine SDF1 regulates migration of dentate granule cells. Development 2002;129:4249-4260.
    • (2002) Development , vol.129 , pp. 4249-4260
    • Bagri, A.1    Gurney, T.2    He, X.3
  • 16
    • 0038666134 scopus 로고    scopus 로고
    • Role of the alpha-chemokine stromal cell-derived factor (SDF-1) in the developing and mature central nervous system
    • Lazarini F, Tham TN, Casanova P, Arenzana-Seisdedos F, Dubois-Dalcq M. Role of the alpha-chemokine stromal cell-derived factor (SDF-1) in the developing and mature central nervous system. Glia 2003;42:139-148.
    • (2003) Glia , vol.42 , pp. 139-148
    • Lazarini, F.1    Tham, T.N.2    Casanova, P.3    Arenzana-Seisdedos, F.4    Dubois-Dalcq, M.5
  • 17
    • 0033119201 scopus 로고    scopus 로고
    • The chemokine receptor CXCR4 is required for the retention of B lineage and granulocytic precursors within the bone marrow microenvironment
    • Ma Q, Jones D, Springer TA. The chemokine receptor CXCR4 is required for the retention of B lineage and granulocytic precursors within the bone marrow microenvironment. Immunity 1999;10:463-471.
    • (1999) Immunity , vol.10 , pp. 463-471
    • Ma, Q.1    Jones, D.2    Springer, T.A.3
  • 18
    • 0031026475 scopus 로고    scopus 로고
    • The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to peripheral blood
    • Aiuti A, Webb IJ, Bleul C, Springer T, Gutierrez-Ramos JC. The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to peripheral blood. J Exp Med 1997;185:111-120.
    • (1997) J Exp Med , vol.185 , pp. 111-120
    • Aiuti, A.1    Webb, I.J.2    Bleul, C.3    Springer, T.4    Gutierrez-Ramos, J.C.5
  • 19
    • 0742306878 scopus 로고    scopus 로고
    • Stem cell plasticity revisited: CXCR4-positive cells expressing mRNA for early muscle, liver and neural cells 'hide out' in the bone marrow
    • Ratajczak MZ, Kucia M, Reca R, Majka M, Janowska-Wieczorek A, Ratajczak J. Stem cell plasticity revisited: CXCR4-positive cells expressing mRNA for early muscle, liver and neural cells 'hide out' in the bone marrow. Leukemia 2004;18:29-40.
    • (2004) Leukemia , vol.18 , pp. 29-40
    • Ratajczak, M.Z.1    Kucia, M.2    Reca, R.3    Majka, M.4    Janowska-Wieczorek, A.5    Ratajczak, J.6
  • 20
    • 10744219598 scopus 로고    scopus 로고
    • Regulation of the chemokine receptor CXCR4 by hypoxia
    • Schioppa T, Uranchimeg B, Saccani A, et al. Regulation of the chemokine receptor CXCR4 by hypoxia. J Exp Med 2003;198:1391-1402.
    • (2003) J Exp Med , vol.198 , pp. 1391-1402
    • Schioppa, T.1    Uranchimeg, B.2    Saccani, A.3
  • 21
    • 4043184065 scopus 로고    scopus 로고
    • Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1
    • Ceradini DJ, Kulkarni AR, Callaghan MJ, et al. Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1. Nat Med 2004;10:858-864.
    • (2004) Nat Med , vol.10 , pp. 858-864
    • Ceradini, D.J.1    Kulkarni, A.R.2    Callaghan, M.J.3
  • 22
    • 20444445920 scopus 로고    scopus 로고
    • Epidermal growth factor and hypoxia-induced expression of CXC chemokine receptor 4 on non-small cell lung cancer cells is regulated by the phosphatidylinositol 3-kinase/PTEN/AKT/ mammalian target of rapamycin signaling pathway and activation of hypoxia inducible factor-1alpha
    • Phillips RJ, Mestas J, Gharaee-Kermani M, et al. Epidermal growth factor and hypoxia-induced expression of CXC chemokine receptor 4 on non-small cell lung cancer cells is regulated by the phosphatidylinositol 3-kinase/PTEN/AKT/ mammalian target of rapamycin signaling pathway and activation of hypoxia inducible factor-1alpha. J Biol Chem 2005; 280:22473-22481.
    • (2005) J Biol Chem , vol.280 , pp. 22473-22481
    • Phillips, R.J.1    Mestas, J.2    Gharaee-Kermani, M.3
  • 23
    • 0038498102 scopus 로고    scopus 로고
    • NF-kappaB promotes breast cancer cell migration and metastasis by inducing the expression of the chemokine receptor CXCR4
    • Helbig G, Christopherson KW II, Bhat-Nakshatri P, et al. NF-kappaB promotes breast cancer cell migration and metastasis by inducing the expression of the chemokine receptor CXCR4. J Biol Chem 2003;278: 21631-21638.
    • (2003) J Biol Chem , vol.278 , pp. 21631-21638
    • Helbig, G.1    Christopherson II, K.W.2    Bhat-Nakshatri, P.3
  • 25
    • 27444443142 scopus 로고    scopus 로고
    • The chemokine SDF-1/ CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes
    • Balabanian K, Lagane B, Infantino S, et al. The chemokine SDF-1/ CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes. J Biol Chem 2005;280:35760-35766.
    • (2005) J Biol Chem , vol.280 , pp. 35760-35766
    • Balabanian, K.1    Lagane, B.2    Infantino, S.3
  • 26
    • 33846220985 scopus 로고    scopus 로고
    • Targeting lung cancer using an infectivity enhanced CXCR4-CRAd
    • Zhu ZB, Rivera AA, Makhija SK, et al. Targeting lung cancer using an infectivity enhanced CXCR4-CRAd. Lung Cancer 2007;55:145-156.
    • (2007) Lung Cancer , vol.55 , pp. 145-156
    • Zhu, Z.B.1    Rivera, A.A.2    Makhija, S.K.3
  • 27
    • 33748474838 scopus 로고    scopus 로고
    • A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development
    • Burns JM, Summers BC, Wang Y, et al. A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development. J Exp Med 2006;203:2201-2213.
    • (2006) J Exp Med , vol.203 , pp. 2201-2213
    • Burns, J.M.1    Summers, B.C.2    Wang, Y.3
  • 28
    • 35548996783 scopus 로고    scopus 로고
    • Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7
    • Sierro F, Biben C, Martínez-Muñoz L, et al. Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7. Proc Natl Acad Sci USA 2007;104: 14759-14764.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 14759-14764
    • Sierro, F.1    Biben, C.2    Martínez-Muñoz, L.3
  • 29
    • 0033215149 scopus 로고    scopus 로고
    • Involvement of phos- phatidylinositol 3-kinase in stromal cell-derived factor-1 alpha-induced lymphocyte polarization and chemotaxis
    • Vicente-Manzanares M, Rey M, Jones DR, et al. Involvement of phos- phatidylinositol 3-kinase in stromal cell-derived factor-1 alpha-induced lymphocyte polarization and chemotaxis. J Immunol 1999;163:4001-4012.
    • (1999) J Immunol , vol.163 , pp. 4001-4012
    • Vicente-Manzanares, M.1    Rey, M.2    Jones, D.R.3
  • 30
    • 0032483419 scopus 로고    scopus 로고
    • The alpha-chemokine, stromal cell-derived factor-1alpha, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathways
    • Ganju RK, Brubaker SA, Meyer J, et al. The alpha-chemokine, stromal cell-derived factor-1alpha, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathways. J Biol Chem 1998;273:23169-23175.
    • (1998) J Biol Chem , vol.273 , pp. 23169-23175
    • Ganju, R.K.1    Brubaker, S.A.2    Meyer, J.3
  • 31
    • 54249110423 scopus 로고    scopus 로고
    • Dual acylation and lipid raft association of Src-family protein tyrosine kinases are required for SDF-1/CXCL12-mediated chemotaxis in the Jurkat human T cell lymphoma cell line
    • Zaman SN, Resek ME, Robbins SM. Dual acylation and lipid raft association of Src-family protein tyrosine kinases are required for SDF-1/CXCL12-mediated chemotaxis in the Jurkat human T cell lymphoma cell line. J Leukoc Biol 2008;84:1082-1091.
    • (2008) J Leukoc Biol , vol.84 , pp. 1082-1091
    • Zaman, S.N.1    Resek, M.E.2    Robbins, S.M.3
  • 32
    • 0038206771 scopus 로고    scopus 로고
    • The stromal derived factor-1/CXCL12-CXC chemokine receptor 4 biological axis in non-small cell lung cancer metastases
    • Phillips RJ, Burdick MD, Lutz M, Belperio JA, Keane MP, Strieter RM. The stromal derived factor-1/CXCL12-CXC chemokine receptor 4 biological axis in non-small cell lung cancer metastases. Am J Respir Crit Care Med 2003;167:1676-1686.
    • (2003) Am J Respir Crit Care Med , vol.167 , pp. 1676-1686
    • Phillips, R.J.1    Burdick, M.D.2    Lutz, M.3    Belperio, J.A.4    Keane, M.P.5    Strieter, R.M.6
  • 33
    • 2342451359 scopus 로고    scopus 로고
    • Stromal-derived factor-1alpha/CXCL12-CXCR 4 axis is involved in the dissemination of NSCLC cells into pleural space
    • Oonakahara K, Matsuyama W, Higashimoto I, Kawabata M, Arimura K, Osame M. Stromal-derived factor-1alpha/CXCL12-CXCR 4 axis is involved in the dissemination of NSCLC cells into pleural space. Am J Respir Cell Mol Biol 2004;30:671-677.
    • (2004) Am J Respir Cell Mol Biol , vol.30 , pp. 671-677
    • Oonakahara, K.1    Matsuyama, W.2    Higashimoto, I.3    Kawabata, M.4    Arimura, K.5    Osame, M.6
  • 34
    • 0942301172 scopus 로고    scopus 로고
    • Regulation of CXCR4-mediated chemotaxis and chemoinvasion of breast cancer cells
    • Fernandis AZ, Prasad A, Band H, Klosel R, Ganju RK. Regulation of CXCR4-mediated chemotaxis and chemoinvasion of breast cancer cells. Oncogene 2004;23:157-167.
    • (2004) Oncogene , vol.23 , pp. 157-167
    • Fernandis, A.Z.1    Prasad, A.2    Band, H.3    Klosel, R.4    Ganju, R.K.5
  • 35
    • 0036786348 scopus 로고    scopus 로고
    • CXCR4-SDF-1 signaling is active in rhabdomyosarcoma cells and regulates locomotion, chemotaxis, and adhesion
    • Libura J, Drukala J, Majka M, et al. CXCR4-SDF-1 signaling is active in rhabdomyosarcoma cells and regulates locomotion, chemotaxis, and adhesion. Blood 2002;100:2597-2606.
    • (2002) Blood , vol.100 , pp. 2597-2606
    • Libura, J.1    Drukala, J.2    Majka, M.3
  • 36
    • 38849173663 scopus 로고    scopus 로고
    • Involvement of matrix metalloproteinase-9 in stromal cell-derived factor-1/CXCR4 pathway of lung cancer metastasis
    • Tang CH, Tan TW, Fu WM, Yang RS. Involvement of matrix metalloproteinase-9 in stromal cell-derived factor-1/CXCR4 pathway of lung cancer metastasis. Carcinogenesis 2008; 29:34-43.
    • (2008) Carcinogenesis , vol.29 , pp. 34-43
    • Tang, C.H.1    Tan, T.W.2    Fu, W.M.3    Yang, R.S.4
  • 37
    • 0033790663 scopus 로고    scopus 로고
    • Differential MMP and TIMP production by human marrow and peripheral blood CD34(+) cells in response to chemokines
    • Janowska-Wieczorek A, Marquez LA, Dobrowsky A, Ratajczak MZ, Cabuhat ML. Differential MMP and TIMP production by human marrow and peripheral blood CD34(+) cells in response to chemokines. Exp Hematol 2000;28:1274-1285.
    • (2000) Exp Hematol , vol.28 , pp. 1274-1285
    • Janowska-Wieczorek, A.1    Marquez, L.A.2    Dobrowsky, A.3    Ratajczak, M.Z.4    Cabuhat, M.L.5
  • 38
    • 0034807055 scopus 로고    scopus 로고
    • The SDF-1-CXCR4 axis stimulates VEGF secretion and activates integrins but does not affect proliferation and survival in lymphohematopoietic cells
    • Kijowski J, Baj-Krzyworzeka M, Majka M, et al. The SDF-1-CXCR4 axis stimulates VEGF secretion and activates integrins but does not affect proliferation and survival in lymphohematopoietic cells. Stem Cells 2001;19:453-466.
    • (2001) Stem Cells , vol.19 , pp. 453-466
    • Kijowski, J.1    Baj-Krzyworzeka, M.2    Majka, M.3
  • 39
    • 0034210221 scopus 로고    scopus 로고
    • The chemokine SDF-1 activates the integrins LFA-1, VLA-4, and VLA-5 on immature human CD34(+) cells: Role in transendothelial/stromal migration and engraftment of NOD/SCID mice
    • Peled A, Kollet O, Ponomaryov T, et al. The chemokine SDF-1 activates the integrins LFA-1, VLA-4, and VLA-5 on immature human CD34(+) cells: role in transendothelial/stromal migration and engraftment of NOD/SCID mice. Blood 2000;95:3289-3296.
    • (2000) Blood , vol.95 , pp. 3289-3296
    • Peled, A.1    Kollet, O.2    Ponomaryov, T.3
  • 40
    • 36049020021 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1 enhances motility and integrin up-regulation through CXCR4, ERK and NF-kappaB-dependent pathway in human lung cancer cells
    • Huang YC, Hsiao YC, Chen YJ, Wei YY, Lai TH, Tang CH. Stromal cell-derived factor-1 enhances motility and integrin up-regulation through CXCR4, ERK and NF-kappaB-dependent pathway in human lung cancer cells. Biochem Pharmacol 2007;74:1702-1712.
    • (2007) Biochem Pharmacol , vol.74 , pp. 1702-1712
    • Huang, Y.C.1    Hsiao, Y.C.2    Chen, Y.J.3    Wei, Y.Y.4    Lai, T.H.5    Tang, C.H.6
  • 41
    • 34250323467 scopus 로고    scopus 로고
    • CXCR4/CXCL12 axis promotes VEGF-mediated tumor angiogenesis through Akt signaling pathway
    • Liang Z, Brooks J, Willard M, et al. CXCR4/CXCL12 axis promotes VEGF-mediated tumor angiogenesis through Akt signaling pathway. Biochem Biophys Res Commun 2007;359:716-722.
    • (2007) Biochem Biophys Res Commun , vol.359 , pp. 716-722
    • Liang, Z.1    Brooks, J.2    Willard, M.3
  • 42
    • 0346121316 scopus 로고    scopus 로고
    • Chemokines, chemokine receptors and adhesion molecules on different human endothelia: Discriminating the tissue-specific functions that affect leucocyte migration
    • Hillyer P, Mordelet E, Flynn G, Male D. Chemokines, chemokine receptors and adhesion molecules on different human endothelia: discriminating the tissue-specific functions that affect leucocyte migration. Clin Exp Immunol 2003;134:431-441.
    • (2003) Clin Exp Immunol , vol.134 , pp. 431-441
    • Hillyer, P.1    Mordelet, E.2    Flynn, G.3    Male, D.4
  • 43
    • 33846425331 scopus 로고    scopus 로고
    • Overexpression of CXCR4 increases migration and proliferation of human adipose tissue stromal cells
    • Cho HH, Kyoung KM, Seo MJ, Kim YJ, Bae YC, Jung JS. Overexpression of CXCR4 increases migration and proliferation of human adipose tissue stromal cells. Stem Cells Dev 2006;15:853-864.
    • (2006) Stem Cells Dev , vol.15 , pp. 853-864
    • Cho, H.H.1    Kyoung, K.M.2    Seo, M.J.3    Kim, Y.J.4    Bae, Y.C.5    Jung, J.S.6
  • 44
    • 23844513413 scopus 로고    scopus 로고
    • Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: Pivotal role of the SDF-1-CXCR4 axis
    • Kucia M, Reca R, Miekus K, et al. Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: pivotal role of the SDF-1-CXCR4 axis. Stem Cells 2005;23:879-894.
    • (2005) Stem Cells , vol.23 , pp. 879-894
    • Kucia, M.1    Reca, R.2    Miekus, K.3
  • 45
    • 33947600329 scopus 로고    scopus 로고
    • Mechanisms of regulation of CXCR4/SDF-1 (CXCL12)-dependent migration and homing in multiple myeloma
    • Alsayed Y, Ngo H, Runnels J, et al. Mechanisms of regulation of CXCR4/SDF-1 (CXCL12)-dependent migration and homing in multiple myeloma. Blood 2007;109:2708-2717.
    • (2007) Blood , vol.109 , pp. 2708-2717
    • Alsayed, Y.1    Ngo, H.2    Runnels, J.3
  • 46
    • 33846985321 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1/chemokine (C-X-C motif) ligand 12 stimulates human hepatoma cell growth, migration, and invasion
    • Sutton A, Friand V, Brule-Donneger S, et al. Stromal cell-derived factor-1/chemokine (C-X-C motif) ligand 12 stimulates human hepatoma cell growth, migration, and invasion. Mol Cancer Res 2007;5:21-33.
    • (2007) Mol Cancer Res , vol.5 , pp. 21-33
    • Sutton, A.1    Friand, V.2    Brule-Donneger, S.3
  • 47
    • 33644789290 scopus 로고    scopus 로고
    • Stromal cell derived factor-1: Its influence on invasiveness and migration of breast cancer cells in vitro, and its association with prognosis and survival in human breast cancer
    • Kang H, Watkins G, Parr C, Douglas-Jones A, Mansel RE, Jiang WG Stromal cell derived factor-1: its influence on invasiveness and migration of breast cancer cells in vitro, and its association with prognosis and survival in human breast cancer. Breast Cancer Res 2005;7: R402-R410.
    • (2005) Breast Cancer Res , vol.7
    • Kang, H.1    Watkins, G.2    Parr, C.3    Douglas-Jones, A.4    Mansel, R.E.5    Jiang, W.G.6
  • 48
    • 0037276938 scopus 로고    scopus 로고
    • Circulating CXCR4-positive stem/progenitor cells compete for SDF-1-positive niches in bone marrow, muscle and neural tissues: An alternative hypothesis to stem cell plasticity
    • Pituch-Noworolska A, Majka M, Janowska-Wieczorek A, et al. Circulating CXCR4-positive stem/progenitor cells compete for SDF-1-positive niches in bone marrow, muscle and neural tissues: an alternative hypothesis to stem cell plasticity. Folia Histochem Cytobiol 2003;41: 13-21.
    • (2003) Folia Histochem Cytobiol , vol.41 , pp. 13-21
    • Pituch-Noworolska, A.1    Majka, M.2    Janowska-Wieczorek, A.3
  • 49
    • 23244435467 scopus 로고    scopus 로고
    • How do stem cells find their way home?
    • Lapidot T, Dar A, Kollet O. How do stem cells find their way home? Blood 2005;106:1901-1910.
    • (2005) Blood , vol.106 , pp. 1901-1910
    • Lapidot, T.1    Dar, A.2    Kollet, O.3
  • 50
    • 33846058844 scopus 로고    scopus 로고
    • The pivotal role of CXCL12 (SDF-1)/ CXCR4 axis in bone metastasis
    • Wang J, Loberg R, Taichman RS. The pivotal role of CXCL12 (SDF-1)/ CXCR4 axis in bone metastasis. Cancer Metastasis Rev 2006;25: 573-587.
    • (2006) Cancer Metastasis Rev , vol.25 , pp. 573-587
    • Wang, J.1    Loberg, R.2    Taichman, R.S.3
  • 51
    • 0035887626 scopus 로고    scopus 로고
    • A possible role for CXCR4 and its ligand, the CXC chemokine stromal cell-derived factor-1, in the development of bone marrow metastases in neuroblastoma
    • Geminder H, Sagi-Assif O, Goldberg L, et al. A possible role for CXCR4 and its ligand, the CXC chemokine stromal cell-derived factor-1, in the development of bone marrow metastases in neuroblastoma. J Immunol 2001;167:4747-4757.
    • (2001) J Immunol , vol.167 , pp. 4747-4757
    • Geminder, H.1    Sagi-Assif, O.2    Goldberg, L.3
  • 52
    • 0035282432 scopus 로고    scopus 로고
    • Involvement of chemokine receptors in breast cancer metastasis
    • Muller A, Homey B, Soto H, et al. Involvement of chemokine receptors in breast cancer metastasis. Nature 2001;410:50-56.
    • (2001) Nature , vol.410 , pp. 50-56
    • Muller, A.1    Homey, B.2    Soto, H.3
  • 53
    • 67650783104 scopus 로고    scopus 로고
    • Overexpression of chemokine receptor cxcr4 in cancer specimens predicts outcome in patients with triple-negative breast cancer
    • abstract 11064
    • Holm NT, Benjamin LJL, Quyen C. Overexpression of chemokine receptor cxcr4 in cancer specimens predicts outcome in patients with triple-negative breast cancer. J Clin Oncol 2008; 26: (20 Suppl) abstract 11064.
    • (2008) J Clin Oncol , vol.26 , Issue.20 SUPPL.
    • Holm, N.T.1    Benjamin, L.J.L.2    Quyen, C.3
  • 54
    • 23744454482 scopus 로고    scopus 로고
    • The expression of functional chemokine receptor CXCR4 is associated with the metastatic potential of human nasopharyngeal carcinoma
    • Hu J, Deng X, Bian X, et al. The expression of functional chemokine receptor CXCR4 is associated with the metastatic potential of human nasopharyngeal carcinoma. Clin Cancer Res 2005;11:4658-4665.
    • (2005) Clin Cancer Res , vol.11 , pp. 4658-4665
    • Hu, J.1    Deng, X.2    Bian, X.3
  • 55
    • 33748548126 scopus 로고    scopus 로고
    • Expression of chemokine CXCL12 and its receptor CXCR4 in human epithelial ovarian cancer: An independent prognostic factor for tumor progression
    • Jiang YP, Wu XH, Shi B, Wu WX, Yin GR. Expression of chemokine CXCL12 and its receptor CXCR4 in human epithelial ovarian cancer: an independent prognostic factor for tumor progression. Gynecol Oncol 2006;103:226-233.
    • (2006) Gynecol Oncol , vol.103 , pp. 226-233
    • Jiang, Y.P.1    Wu, X.H.2    Shi, B.3    Wu, W.X.4    Yin, G.R.5
  • 56
    • 15244341145 scopus 로고    scopus 로고
    • Invasive characteristics of human prostatic epithelial cells: Understanding the metastatic process
    • Hart CA, Brown M, Bagley S, Sharrard M, Clarke NW. Invasive characteristics of human prostatic epithelial cells: understanding the metastatic process. Br J Cancer 2005;92:503-512.
    • (2005) Br J Cancer , vol.92 , pp. 503-512
    • Hart, C.A.1    Brown, M.2    Bagley, S.3    Sharrard, M.4    Clarke, N.W.5
  • 57
    • 2942692286 scopus 로고    scopus 로고
    • CXCR4 antagonist inhibits stromal cell-derived factor 1-induced migration and invasion of human pancreatic cancer
    • Mori T, Doi R, Koizumi M, et al. CXCR4 antagonist inhibits stromal cell-derived factor 1-induced migration and invasion of human pancreatic cancer. Mol Cancer Ther 2004;3:29-37.
    • (2004) Mol Cancer Ther , vol.3 , pp. 29-37
    • Mori, T.1    Doi, R.2    Koizumi, M.3
  • 58
    • 9244234390 scopus 로고    scopus 로고
    • CXCR4 regulates growth of both primary and metastatic breast cancer
    • Smith MC, Luker KE, Garbow JR, et al. CXCR4 regulates growth of both primary and metastatic breast cancer. Cancer Res 2004;64:8604-8612.
    • (2004) Cancer Res , vol.64 , pp. 8604-8612
    • Smith, M.C.1    Luker, K.E.2    Garbow, J.R.3
  • 59
    • 33751319000 scopus 로고    scopus 로고
    • Stromal derived factor-1 (SDF-1/ CXCL12) and CXCR4 in renal cell carcinoma metastasis
    • Pan J, Mestas J, Burdick MD, et al. Stromal derived factor-1 (SDF-1/ CXCL12) and CXCR4 in renal cell carcinoma metastasis. Mol Cancer 2006; 5:56.
    • (2006) Mol Cancer , vol.5 , pp. 56
    • Pan, J.1    Mestas, J.2    Burdick, M.D.3
  • 60
    • 34547634399 scopus 로고    scopus 로고
    • CXC chemokine receptor-4 antagonist blocks both growth of primary tumor and metastasis of head and neck cancer in xenograft mouse models
    • Yoon Y, Liang Z, Zhang X, et al. CXC chemokine receptor-4 antagonist blocks both growth of primary tumor and metastasis of head and neck cancer in xenograft mouse models. Cancer Res 2007;67:7518-7524.
    • (2007) Cancer Res , vol.67 , pp. 7518-7524
    • Yoon, Y.1    Liang, Z.2    Zhang, X.3
  • 61
    • 2442484449 scopus 로고    scopus 로고
    • The SDF-1/CXCL 12/CXCR4 biological axis in non-small cell lung cancer metastases
    • Belperio JA, Phillips RJ, Burdick MD, Lutz M, Keane M, Strieter R. The SDF-1/CXCL 12/CXCR4 biological axis in non-small cell lung cancer metastases. Chest 2004. 125(5 Suppl): 156S.
    • (2004) Chest , vol.125 , Issue.5 SUPPL.
    • Belperio, J.A.1    Phillips, R.J.2    Burdick, M.D.3    Lutz, M.4    Keane, M.5    Strieter, R.6
  • 62
    • 28544440733 scopus 로고    scopus 로고
    • Differential expression of CXCR4 is associated with the metastatic potential of human non-small cell lung cancer cells
    • Su L, Zhang J, Xu H, et al. Differential expression of CXCR4 is associated with the metastatic potential of human non-small cell lung cancer cells. Clin Cancer Res 2005;11:8273-8280.
    • (2005) Clin Cancer Res , vol.11 , pp. 8273-8280
    • Su, L.1    Zhang, J.2    Xu, H.3
  • 63
    • 2342432307 scopus 로고    scopus 로고
    • Chemokine receptor CXCR4 and early-stage non-small cell lung cancer: Pattern of expression and correlation with outcome
    • Spano JP, Andre F, Morat L, et al. Chemokine receptor CXCR4 and early-stage non-small cell lung cancer: pattern of expression and correlation with outcome. Ann Oncol 2004;15:613-617.
    • (2004) Ann Oncol , vol.15 , pp. 613-617
    • Spano, J.P.1    Andre, F.2    Morat, L.3
  • 64
    • 27644562737 scopus 로고    scopus 로고
    • Role of CXCR4 chemokine receptor blockade using AMD3100 for mobilization of autologous hematopoietic progenitor cells
    • Flomenberg N, DiPersio J, Calandra G. Role of CXCR4 chemokine receptor blockade using AMD3100 for mobilization of autologous hematopoietic progenitor cells. Acta Haematol 2005;114:198-205.
    • (2005) Acta Haematol , vol.114 , pp. 198-205
    • Flomenberg, N.1    DiPersio, J.2    Calandra, G.3
  • 65
    • 67650802290 scopus 로고    scopus 로고
    • Phase I/II study of CTCE-9908, a novel anticancer agent that inhibits CXCR4, in patients with advanced solid cancers
    • Abstract
    • Hotte S. Phase I/II study of CTCE-9908, a novel anticancer agent that inhibits CXCR4, in patients with advanced solid cancers. AACR Molecular Therapy Conference. Abstract, 2007.
    • (2007) AACR Molecular Therapy Conference
    • Hotte, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.