Are chemokines the third major system in the brain?

Journal of Leukocyte Biology

Volumn 78, Issue 6, 2005, Pages 1204-1209

  Adler, Martin W ^a   Rogers, Thomas J ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Heterologous desensitization; Interneuronal communication; Neuromodulators; Opioids

Indexed keywords

CANNABINOID; CHEMOKINE; CHEMOKINE RECEPTOR; CX3C CHEMOKINE; FRACTALKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1; NEUROPEPTIDE; NEUROTRANSMITTER; OPIATE; STROMAL CELL DERIVED FACTOR 1;

BRAIN CORTEX; BRAIN DEVELOPMENT; BRAIN FUNCTION; CELL COMMUNICATION; CELL MIGRATION; CEREBELLUM; CONFERENCE PAPER; GLIA; HIPPOCAMPUS; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; LIMBIC SYSTEM; NERVE CELL; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; T LYMPHOCYTE; THALAMUS;

ANIMALS; BRAIN; CELL COMMUNICATION; CHEMOKINES; HUMANS; NEUROGLIA; NEURONS; NEUROPEPTIDES; NEUROTRANSMITTER AGENTS; PSYCHOTROPIC DRUGS; RECEPTORS, CHEMOKINE; SIGNAL TRANSDUCTION;

EID: 28844433347     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0405222     Document Type: Conference Paper

References (39)

1. Ambrosini, E., Aloisi, F. (2004) Chemokines and glial cells: a complex network in the central nervous system. Neurochem. Res. 29, 1017-1038.
2. Bajetto, A., Bonavia, R., Barbera, S., Florio, T., Schettini, G. (2001) Chemokines and their receptors in the central nervous system. Front. Neuroendocrinol. 22, 147-184.
3. van der Meer, P., Ulrich, A. M., González-Scarano, F., Lavi, E, (2000) Immunohistochemical analysis of CCR2, CCR3, CCR5, and CXCR4 in the human brain: potential mechanisms for HIV dementia. Exp. Mol. Pathol. 69, 192-201.
4. Banisadr, G., Quéraud-Lesaux, F., Boutterin, M, C., Pélaprat, D., Zalc, B., Rostène, W., Haour, F., Parsadaniantz, S. M. (2002) Distribution, cellular localization and functional role of CCR2 chemokine receptors in adult rat brain. J. Neurochem. 81, 257-269.
5. Horuk, R., Martin, A. W., Wang, Z., Schweitzer, L., Gerassimides, A., Guo, H., Lu, Z., Hesselgesser, J., Perez, H. D., Kim, J., Parker, J., Hadley, T. J., Peiper, S. C. (1997) Expression of chemokine receptors by subsets of neurons in the central nervous system. J. Immunol. 158, 2882-2890.
6. Banisadr, G., Fontanges, P., Haour, F., Kitabgi, P., Rostène, W., Parsadaniantz, S. M. (2002) Neuroanatomical distribution of CXCR4 in adult rat brain and its localization in cholinergic and dopaminergic neurons. Eur. J. Neurosci. 16, 1661-1671.
7. Coughlan, C. M., McManus, C. M., Sharron, M., Gao, Z.-Y., Murphy, D., Jaffer, S., Choe, W., Chen, W., Hesselgesser, J., Gaylord, H., Kalyuzhny, A., Lee, V. M. Y., Wolf, B., Doms, R. W., Kilson, D. L. (2000) Expression of multiple functional chemokine receptors and monocyte chemoattractant protein-1 in human neurons. Neuroscience 97, 591-600.
8. 3CR1 in neural progenitor cells isolated from the subventricular zone of the adult rat brain. Neurosci. Lett. 355, 236-240.
9. Hickey, W. F., Hsu, B. L., Kimura, H. (1991) T-lymphocyte entry into the central nervous system. J. Neurosci. Res. 28, 254-260.
10. Carrithers, M. D., Visintin, I., Viret, C., Janeway, C. A. (2002) Role of genetic background in P selectin-dependent immune surveillance of the central nervous system. J. Neuroimmunol. 129, 51-57.
11. Cooper, J. R., Bloom, F. E., Roth, R. H. (2003) The Biochemical Basis of Neuropharmacology; New York, NY. Oxford University Press.
12. Grimm, M. C., Ben-Baruch, A., Taub, D. D., Howard, O. M., Resau, J. H., Wang, J. M., Ali, H., Richardson, R., Snyderman, R., Oppenheim, J. J. (1998) Opiates transdeactivate chemokine receptors: δ and μ opiate receptor-mediated heterologous desensitization. J. Exp. Med. 188, 317-325.
13. Szabo, I., Chen, X. H., Xin, L., Adler, M. W., Howard, O. M. Z., Oppenheim, J. J., Rogers, T. J. (2002) Heterologous desensitization of opioid receptors by chemokines inhibits chemotaxis and enhances the perception of pain. Proc. Natl. Acad. Sci. USA 99, 10276-10281.
14. Steele, A. D., Szabo, I., Bednar, F., Rodgers, R. J. (2002) Interactions between opioid and chemokine receptors: heterologous desensitization. Cytokine Growth Factor Rev. 13, 209-222.
15. Rogers, T. J., Steele, A. D., Howard, O. M. Z., Oppenheim, J. J., (2000) Bidirectional heterologous desensitization of opioid and chemokine receptors. Ann N. Y. Acad. Sci. 917, 19-28.
16. Szabo, I., Wetzel, M. A., Zhang, N., Steele, A. D., Kaminsky, D. E., Chen, C., Liu-Chen, L.-Y., Bednar, F., Henderson, E. E., Howard, O. M. Z., Oppenheim, J. J., Rogers, T. J. (2003) Selective inactivation of CCR5 and decreased infectivity of R5 HIV-1 strains mediated by opioid-induced heterologous desensitization. J. Leukoc. Biol. 74, 1074-1082.
17. Ali, H., Richardson, R. M., Haribabu, B., Snyderman, R. (1999) Chemoattractant receptor cross-desensitization. J. Biol. Chem. 274, 6027-6030.
18. Shen, W., Li, B., Wetzel, M. A., Rogers, T. J., Henderson, E. E., Su, S. B., Gong, W., Le, Y., Sargeant, R., Dimitrov, D. S., Oppenheim, J. J., Wang, J. M. (2000) Down-regulation of the chemokine receptor CCR5 by activation of chemotactic formyl peptide receptor in human monocytes. Blood 96, 2887-2894.
19. Le, Y., Wetzel, M. A., Shen, W., Gong, W., Rogers, T. J., Henderson, E. E., Wang, J. M. (2001) Desensitization of chemokine receptor CCR5 in dendritic cells at the early stage of differentiation by activation of formyl peptide receptors. Clin. Immunol. 99, 365-372.
20. Li, B. Q., Wetzel, M. A., Mikovits, J. A., Henderson, E. E., Rogers, T. J., Gong, W., Le, Y., Ruscetti, F. W., Wang, J. M. (2001) The synthetic peptide WKYMVm attenuates the function of the chemokine receptors CCR5 and CXCR4 through activation of formyl peptide receptor-like 1. Blood 97, 2941-2947.
21. Pizziketti, R. J., Pressman, N. S., Geller, E. B., Cowan, A., Adler, M. W. (1985) Rat cold water tail-flick: a novel analgesic test that distinguishes opioid agonists from mixed agonist-antagonists. Eur. J. Pharmacol. 119, 23-29.
22. Chen, C., Li, J., Bot, G., Szabo, L, Rogers, T. J., Liu-Chen, L.-Y. (2004) Heterodimerization and cross-desensitization between the μ-opioid receptor and the chemokine CCR5 receptor. Eur. J. Pharmacol. 483, 175-186.
23. Rogers, T. J., Peterson, P. K. (2003) Opioid G protein-coupled receptors: signals at the crossroads of inflammation. Trends Immunol. 24, 116-121.
24. Mizuno, T., Kawanokuchi, J., Numata, K., Suzumura, A. (2003) Production and neuroprotective function of fractalkine in the central nervous system. Brain Res. 979, 65-70.
25. Westmoreland, S. V., Alvarez, X., Debakker, C., Aye, P., Wilson, M. L., Williams, K. C., Lackner, A. A. (2002) Developmental expression patterns of CCR5 and CXCR4 in the rhesus macaque brain. J. Neuroimmunol. 122, 146-158.
26. Ragozzino, D., Renzi, M., Giovannelli, A., Eusebi, F. (2002) Stimulation of chemokine CXC receptor 4 induces synaptic depression of evoked parallel fibers inputs onto Purkinje neurons in mouse cerebellum. J. Neuroimmunol. 127, 30-36.
27. Cho, C., Miller, R. J. (2002) Chemokine receptors and neural function. J Neurovirol. 8, 573-584.
28. Bajetto, A., Bonavia, R., Barbero, S., Schettini, G. (2002) Characterization of chemokines and their receptors in the central nervous system: physiopathological implications. J. Neurochem. 82, 1311-1329.
29. Zheng, J., Thylin, M. R., Ghorpade, A., Xiong, H., Persidsky, Y., Cotter, R., Niemann, D., Che, M. H., Zeng, Y.-C., Gelbard, H. A., Shepard, R. B., Swartz, J. M., Gendelman, H. E. (1999) Intracellular CXCR4 signaling, neuronal apoptosis and neuropathogenic mechanisms of HIV-1-associated dementia. J. Neuroimmunol. 98, 185-200.
30. Stumm, R. K., Rummell, J., Junker, V., Culmsee, C., Pfeiffer, M., Kriegistein, J., Höllt, V., Schulz, S. (2002) A dual role for the SDF-1/CXCR4 chemokine receptor system in adult brain: isoform-selective regulation of SDF-I expression modulates CXCR4-dependent neuronal plasticity and cerebral leukocyte recruitment after focal ischemia. J. Neurosci. 22, 5865-5878.
31. Tran, P. B., Miller, R. J. (2003) Chemokine receptors in the brain: a developing story. J. Comp, Neurol. 457, 1-6.
32. Ma, Q., Jones, D., Borghesani, P. R., Segal, R. A., Nagasawa, T., Kishimoto, T., Bronson, R. T., Springer, T. A. (1998) Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4-and SDF-1-deficient mice. Proc. Natl. Acad. Sci. USA 95, 9448-9453.
33. Lu, M., Grove, E. A., Miller, R. J. (2002) Abnormal development of the hippocampal dentate gyrus in mice lacking the CXCR4 chemokine receptor. Proc. Natl. Acad. Sci. USA 99, 7090-7095.
34. Bagri, A., Gurney, T., He, X., Zou, Y. R., Littman, D. R., Tessier-Lavigne, M., Pleasure, S. J. (2002) The chemokine SDF1 regulates migration of dentate granule cells. Development 129, 4249-4260.
35. Zou, Y. R., Kottmann, A. H., Kuroda, M., Taniuchi, L, Littman, D. R. (1998) Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. Nature 393, 595-599.
36. McGrath, K. E., Koniski, A. D., Maltby, K. M., McGann, J. K., Palis, J. (1999) Embryonic expression and function of the chemokine SDF-1 and its receptor, CXCR4. Dev. Biol. 213, 442-456.
37. Zhu, Y., Yu, T., Zhang, X. C., Nagasawa, T., Wu, J. Y., Rao, Y. (2002) Role of the chemokine SDF-1 as the meningeal attractant for embryonic cerebellar neurons. Nat. Neurosci. 5, 719-720.
38. Jung, S., Aliberti, J., Graemmel, P., Sunshine, M. J., Kreutzberg, G. W., Sher, A., Littman, D. R. (2000) Analysis of fractalkine receptor CX(S)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion. Mol. Cell. Biol. 20, 4106-4114.
39. Cook, D. N., Chen, S. C., Sullivan, L. M., Manfra, D. J., Wiekowski, M. T., Presser, D. M., Vassileva, G., Lira, S. A. (2001) Generation and analysis of mice lacking the chemokine fractalkine. Mol. Cell. Biol. 21, 3159-3165.