Down-regulation of CXCL12 mRNA expression by promoter hypermethylation and its association with metastatic progression in human breast carcinomas

Journal of Cancer Research and Clinical Oncology

Volumn 135, Issue 1, 2009, Pages 91-102

  Zhou, Wei ^a,b   Jiang, Zheng ^c   Liu, Ningbo ^b   Xu, Fenghua ^b   Wen, Peie ^d   Liu, Yanbing ^b   Zhong, Weixia ^b   Song, Xianrang ^b   Chang, Xiaotian ^d   Zhang, Xiuli ^b   Wei, Guangsheng ^b   Yu, Jinming ^b  

^a SHANDONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b SHANDONG CANCER HOSPITAL AND INSTITUTE   (China)

^c SHANDONG UNIVERSITY   (China)

^d SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG FIRST MEDICAL UNIVERSITY   (China)

Author keywords

Cancer; Chemokine; CXCR4; DNA hypermethylation; Metastasis

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3B; ESTROGEN RECEPTOR; MESSENGER RNA; STROMAL CELL DERIVED FACTOR 1;

ADULT; AGED; ARTICLE; BREAST CARCINOMA; BREAST METASTASIS; CANCER CLASSIFICATION; CANCER GROWTH; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; METHYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION;

ADULT; AGED; AGED, 80 AND OVER; BREAST; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; CARCINOMA, INTRADUCTAL, NONINFILTRATING; CARCINOMA, LOBULAR; CHEMOKINE CXCL12; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOENZYME TECHNIQUES; LYMPHATIC METASTASIS; MIDDLE AGED; PROMOTER REGIONS, GENETIC; RECEPTORS, CXCR4; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 56649120579     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00432-008-0435-x     Document Type: Article

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