메뉴 건너뛰기




Volumn 91, Issue 5, 2006, Pages 803-806

Regulation of physiological responses to continuous and intermittent hypoxia by hypoxia-inducible factor 1

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 1BETA; OXYGEN; PROTEIN SUBUNIT; TRANSCRIPTION FACTOR;

EID: 33747621613     PISSN: 09580670     EISSN: 1469445X     Source Type: Journal    
DOI: 10.1113/expphysiol.2006.033498     Document Type: Conference Paper
Times cited : (167)

References (33)
  • 1
    • 0026049416 scopus 로고
    • Enhancer element at the 3′-flanking region controls transcriptional response to hypoxia in the human erythropoietin gene
    • Beck I, Ramirez S, Weinmann R & Caro J (1991). Enhancer element at the 3′-flanking region controls transcriptional response to hypoxia in the human erythropoietin gene. J Biol Chem 266, 15563-15566.
    • (1991) J Biol Chem , vol.266 , pp. 15563-15566
    • Beck, I.1    Ramirez, S.2    Weinmann, R.3    Caro, J.4
  • 2
    • 0035834409 scopus 로고    scopus 로고
    • A conserved family of prolyl-4-hydroxylases that modify HIF
    • Bruick RK & McKnight SL (2001). A conserved family of prolyl-4-hydroxylases that modify HIF. Science 294, 1337-1340.
    • (2001) Science , vol.294 , pp. 1337-1340
    • Bruick, R.K.1    McKnight, S.L.2
  • 4
    • 0032581277 scopus 로고    scopus 로고
    • Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
    • Carmeliet P, Dor Y, Herbert JM, Fukumura D, Brusselmans K, Dewerchin M et al. (1998). Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis. Nature 394, 485-490.
    • (1998) Nature , vol.394 , pp. 485-490
    • Carmeliet, P.1    Dor, Y.2    Herbert, J.M.3    Fukumura, D.4    Brusselmans, K.5    Dewerchin, M.6
  • 5
    • 0032891708 scopus 로고    scopus 로고
    • Induction and nuclear translocation of hypoxia-inducible factor-1 (HIF-1): Heterodimerization with ARNT is not necessary for nuclear accumulation of HIF-1α
    • Chilov D, Camenisch G, Kvietikova I, Ziegler U, Gassmann M & Wenger RH (1999). Induction and nuclear translocation of hypoxia-inducible factor-1 (HIF-1): heterodimerization with ARNT is not necessary for nuclear accumulation of HIF-1α. J Cell Sci 112, 1203-1212.
    • (1999) J Cell Sci , vol.112 , pp. 1203-1212
    • Chilov, D.1    Camenisch, G.2    Kvietikova, I.3    Ziegler, U.4    Gassmann, M.5    Wenger, R.H.6
  • 6
    • 17944375360 scopus 로고    scopus 로고
    • C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation
    • Epstein AC, Gleadle JM, McNeill LA, Hewitson KS, O'Rourke J, Mole DR et al. (2001). C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation. Cell 107, 43-54.
    • (2001) Cell , vol.107 , pp. 43-54
    • Epstein, A.C.1    Gleadle, J.M.2    McNeill, L.A.3    Hewitson, K.S.4    O'Rourke, J.5    Mole, D.R.6
  • 7
    • 24144493814 scopus 로고    scopus 로고
    • Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing
    • Guzy RD, Hoyos B, Robin E, Chen H, Liu L, Mansfield KD et al. (2005). Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing. Cell Metab 1, 401-408.
    • (2005) Cell Metab , vol.1 , pp. 401-408
    • Guzy, R.D.1    Hoyos, B.2    Robin, E.3    Chen, H.4    Liu, L.5    Mansfield, K.D.6
  • 8
    • 1642286962 scopus 로고    scopus 로고
    • Modulating the hypoxia-inducible factor signaling pathway
    • Hewitson KS, McNeill LA & Schofield CJ (2004). Modulating the hypoxia-inducible factor signaling pathway. Curr Pharm Des 10, 821-833.
    • (2004) Curr Pharm des , vol.10 , pp. 821-833
    • Hewitson, K.S.1    McNeill, L.A.2    Schofield, C.J.3
  • 14
    • 0033525830 scopus 로고    scopus 로고
    • Regulation of the hypoxia-inducible transcription factor 1α by the ubiquitin-proteasome pathway
    • Kallio PJ, Wilson WJ, O'Brien S, Makino Y & Poellinger L (1999). Regulation of the hypoxia-inducible transcription factor 1α by the ubiquitin-proteasome pathway. J Biol Chem 274, 6519-6525.
    • (1999) J Biol Chem , vol.274 , pp. 6519-6525
    • Kallio, P.J.1    Wilson, W.J.2    O'Brien, S.3    Makino, Y.4    Poellinger, L.5
  • 15
    • 0037154262 scopus 로고    scopus 로고
    • Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α
    • Kline DD, Peng Y, Manalo DJ, Semenza GL & Prabhakar NR (2002). Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α. Proc Natl Acad Sci U S A 99, 821-826.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 821-826
    • Kline, D.D.1    Peng, Y.2    Manalo, D.J.3    Semenza, G.L.4    Prabhakar, N.R.5
  • 16
    • 0033562569 scopus 로고    scopus 로고
    • Defective vascularization of HIF-1α-null embryos is not associated with VEGF deficiency but with mesenchymal cell death
    • Kotch LE, Iyer NV, Laughner E & Semenza GL (1999). Defective vascularization of HIF-1α-null embryos is not associated with VEGF deficiency but with mesenchymal cell death. Dev Biol 209, 254-267.
    • (1999) Dev Biol , vol.209 , pp. 254-267
    • Kotch, L.E.1    Iyer, N.V.2    Laughner, E.3    Semenza, G.L.4
  • 17
    • 33646775277 scopus 로고    scopus 로고
    • Altered metabolic responses to intermittent hypoxia in mice with partial deficiency of hypoxia-inducible factor 1α
    • Li J, Bosch-Marce M, Nanayakkara A, Savransky V, Fried SK et al. (2006). Altered metabolic responses to intermittent hypoxia in mice with partial deficiency of hypoxia-inducible factor 1α. Physiol Genomics 25, 450-457.
    • (2006) Physiol Genomics , vol.25 , pp. 450-457
    • Li, J.1    Bosch-Marce, M.2    Nanayakkara, A.3    Savransky, V.4    Fried, S.K.5
  • 18
    • 24144447915 scopus 로고    scopus 로고
    • Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activation
    • Mansfield KD, Guzy RD, Pan Y, Young RM, Cash TP et al. (2005). Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activation. Cell Metab 1, 393-399.
    • (2005) Cell Metab , vol.1 , pp. 393-399
    • Mansfield, K.D.1    Guzy, R.D.2    Pan, Y.3    Young, R.M.4    Cash, T.P.5
  • 19
    • 0033587146 scopus 로고    scopus 로고
    • The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
    • Maxwell PH, Wiesener MS, Chang GW, Clifford SC, Vaux EC, Cockman ME et al. (1999). The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature 399, 271-275.
    • (1999) Nature , vol.399 , pp. 271-275
    • Maxwell, P.H.1    Wiesener, M.S.2    Chang, G.W.3    Clifford, S.C.4    Vaux, E.C.5    Cockman, M.E.6
  • 20
    • 0025885693 scopus 로고
    • Functional analysis of an oxygen-regulated transcriptional enhancer lying 3′ to the mouse erythropoietin gene
    • Pugh CW, Tan CC, Jones RW & Ratcliffe PJ (1991). Functional analysis of an oxygen-regulated transcriptional enhancer lying 3′ to the mouse erythropoietin gene. Proc Natl Acad Sci U S A 88, 10553-10557.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 10553-10557
    • Pugh, C.W.1    Tan, C.C.2    Jones, R.W.3    Ratcliffe, P.J.4
  • 21
    • 0032100732 scopus 로고    scopus 로고
    • HIF-1α is required for solid tumor formation and embryonic vascularization
    • Ryan HE, Lo J & Johnson RS (1998). HIF-1α is required for solid tumor formation and embryonic vascularization. EMBO J 17, 3005-3015.
    • (1998) EMBO J , vol.17 , pp. 3005-3015
    • Ryan, H.E.1    Lo, J.2    Johnson, R.S.3
  • 22
    • 0030961006 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1α (HIF-1α) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes
    • Salceda S & Caro J (1997). Hypoxia-inducible factor 1α (HIF-1α) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes. J Biol Chem 272, 22642-22647.
    • (1997) J Biol Chem , vol.272 , pp. 22642-22647
    • Salceda, S.1    Caro, J.2
  • 23
    • 33645786505 scopus 로고    scopus 로고
    • Development of novel therapeutic strategies that target HIF-1
    • Semenza GL (2006). Development of novel therapeutic strategies that target HIF-1. Expert Opin Ther Targets 10, 267-280.
    • (2006) Expert Opin Ther Targets , vol.10 , pp. 267-280
    • Semenza, G.L.1
  • 24
    • 0026075610 scopus 로고
    • Hypoxia-inducible nuclear factors bind to an enhancer located 3′ to the human erythropoietin gene
    • Semenza GL, Nejfelt MK, Chi SM & Antonarakis SE (1991). Hypoxia-inducible nuclear factors bind to an enhancer located 3′ to the human erythropoietin gene. Proc Natl Acad Sci U S A 88, 5680-5684.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 5680-5684
    • Semenza, G.L.1    Nejfelt, M.K.2    Chi, S.M.3    Antonarakis, S.E.4
  • 25
    • 0026468180 scopus 로고
    • A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation
    • Semenza GL & Wang GL (1992). A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Mol Cell Biol 12, 5447-5454.
    • (1992) Mol Cell Biol , vol.12 , pp. 5447-5454
    • Semenza, G.L.1    Wang, G.L.2
  • 26
    • 0034815688 scopus 로고    scopus 로고
    • Partial HIF-1α deficiency impairs pulmonary arterial myocyte electrophysiological responses to chronic hypoxia
    • Shimoda LA, Manalo DJ, Sham JSK, Semenza GL & Sylvester JT (2001). Partial HIF-1α deficiency impairs pulmonary arterial myocyte electrophysiological responses to chronic hypoxia. Am J Physiol 281, L202-L208.
    • (2001) Am J Physiol , vol.281
    • Shimoda, L.A.1    Manalo, D.J.2    Sham, J.S.K.3    Semenza, G.L.4    Sylvester, J.T.5
  • 27
    • 0033870281 scopus 로고    scopus 로고
    • The expression and distribution of the hypoxia-inducible factors HIF-1α and HIF-2α in normal human tissues, cancers, and tumor-associated macrophages
    • Talks KL, Turley H, Gatter KC, Maxwell PH, Pugh CW et al. (2000). The expression and distribution of the hypoxia-inducible factors HIF-1α and HIF-2α in normal human tissues, cancers, and tumor-associated macrophages. Am J Pathol 157, 411-421.
    • (2000) Am J Pathol , vol.157 , pp. 411-421
    • Talks, K.L.1    Turley, H.2    Gatter, K.C.3    Maxwell, P.H.4    Pugh, C.W.5
  • 29
    • 0028816847 scopus 로고
    • Purification and characterization of hypoxia-inducible factor 1
    • Wang GL & Semenza GL (1995). Purification and characterization of hypoxia-inducible factor 1. J Biol Chem 270, 1230-1237.
    • (1995) J Biol Chem , vol.270 , pp. 1230-1237
    • Wang, G.L.1    Semenza, G.L.2
  • 30
    • 0033104847 scopus 로고    scopus 로고
    • Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α
    • Yu AY, Shimoda LA, Iyer NV, Huso DL, Sun X, McWilliams R, Beaty T et al. (1999). Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α. J Clin Invest 103, 691-696.
    • (1999) J Clin Invest , vol.103 , pp. 691-696
    • Yu, A.Y.1    Shimoda, L.A.2    Iyer, N.V.3    Huso, D.L.4    Sun, X.5    McWilliams, R.6    Beaty, T.7
  • 31
    • 0035859692 scopus 로고    scopus 로고
    • HIF-1α binding to VHL is regulated by stimulus-sensitive proline hydroxylation
    • Yu F, White SB, Zhao Q & Lee FS (2001). HIF-1α binding to VHL is regulated by stimulus-sensitive proline hydroxylation. Proc Natl Acad Sci U S A 98, 9630-9635.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 9630-9635
    • Yu, F.1    White, S.B.2    Zhao, Q.3    Lee, F.S.4
  • 32
    • 0034213146 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible factor 1α in human brain tumors: Association with angiogenesis, invasion, and progression
    • Zagzag D, Zhong H, Scalzitti JM, Laughner E, Simons JW & Semenza GL (2000). Expression of hypoxia-inducible factor 1α in human brain tumors: association with angiogenesis, invasion, and progression. Cancer 88, 2606-2618.
    • (2000) Cancer , vol.88 , pp. 2606-2618
    • Zagzag, D.1    Zhong, H.2    Scalzitti, J.M.3    Laughner, E.4    Simons, J.W.5    Semenza, G.L.6
  • 33
    • 0033571682 scopus 로고    scopus 로고
    • Overexpression of hypoxia-inducible factor 1α in common human cancers and their metastases
    • Zhong H, De Marzo AM, Laughner E, Lim M, Hilton DA, Zagzag D et al. (1999). Overexpression of hypoxia-inducible factor 1α in common human cancers and their metastases. Cancer Res 59, 5830-5835.
    • (1999) Cancer Res , vol.59 , pp. 5830-5835
    • Zhong, H.1    De Marzo, A.M.2    Laughner, E.3    Lim, M.4    Hilton, D.A.5    Zagzag, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.