SHARP1 suppresses breast cancer metastasis by promoting degradation of hypoxia-inducible factors

Nature

Volumn 487, Issue 7407, 2012, Pages 380-384

  Montagner, Marco ^a   Enzo, Elena ^a   Forcato, Mattia ^b   Zanconato, Francesca ^a   Parenti, Anna ^c   Rampazzo, Elena ^c   Basso, Giuseppe ^c   Leo, Genesio ^d   Rosato, Antonio ^e   Bicciato, Silvio ^b   Cordenonsi, Michelangelo ^a   Piccolo, Stefano ^a  

^a UNIVERSITY OF PADUA MEDICAL SCHOOL   (Italy)

^b UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^c UNIVERSITY OF PADOVA   (Italy)

^d San Bassiano Hospital   (Italy)

^e VENETO INSTITUTE OF ONCOLOGY IOV IRCCS   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; PEPTIDES AND PROTEINS; PROTEIN P63; PROTEIN SHARP1; UNCLASSIFIED DRUG;

CANCER; CYTOLOGY; HYPOXIA; INHIBITION; MOLECULAR ANALYSIS; OXYGEN; PHENOTYPE;

ARTICLE; CELL MIGRATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; METASTASIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; TRIPLE NEGATIVE BREAST CANCER;

BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BREAST NEOPLASMS; CYCLIN G2; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; KAPLAN-MEIER ESTIMATE; MULTIVARIATE ANALYSIS; NEOPLASM METASTASIS;

EID: 84863982875     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature11207     Document Type: Article

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