Hypoxia-inducible factor asparaginyl hydroxylase (FIH-1) catalyses hydroxylation at the β-carbon of asparagine-803

Biochemical Journal

Volumn 367, Issue 3, 2002, Pages 571-575

  McNeill, Luke A ^a   Hewitson, Kirsty S ^a   Claridge, Timothy D ^a   Seibel, Jürgen F ^a   Horsfall, Louise E ^a   Schofield, Christopher J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Asparagine hydroxylation; Factor inhibiting hypoxia inducible factor 1 (FIH 1); Hypoxia; Oxygen sensing; Oxygenase

Indexed keywords

CATALYSIS; ENZYMES; HYDROXYLATION; ISOMERS; NUCLEAR MAGNETIC RESONANCE;

ABROGATION;

BIOCHEMISTRY;

ASPARAGINE; ASPARTIC ACID; CARBON; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PROTEIN P300;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CRYSTAL STRUCTURE; DIMERIZATION; HYDROXYLATION; ISOMERISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; SEQUENCE ANALYSIS; TRANSACTIVATION;

AMINO ACID SEQUENCE; ASPARAGINE; CARBON; CATALYSIS; DNA-BINDING PROTEINS; HYDROXYLATION; HYPOXIA-INDUCIBLE FACTOR 1; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; NUCLEAR PROTEINS; TRANSCRIPTION FACTORS;

EID: 0036846033     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20021162     Document Type: Article

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