Process analytical technology (PAT) tools for the cultivation step in biopharmaceutical production

Engineering in Life Sciences

Volumn 13, Issue 3, 2013, Pages 212-223

  Streefland, Mathieu ^a   Martens, Dirk E ^a   Beuvery, E Coen ^b   Wijffels, René H ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b PAT Consultancy ^*  (Netherlands)

Author keywords

Biopharmaceutical cultivation; Biopharmaceutical manufacturing; Bioreactor monitoring; Process analytical technology (PAT); Quality by design (QbD)

Indexed keywords

BIOPHARMACEUTICAL PRODUCTS; BIOREACTOR MONITORING; CULTIVATION PROCESS; MONITORING AND CONTROLLING; PHARMACEUTICAL PROCESS; PROCESS ANALYTICAL TECHNOLOGY; QUALITY BY DESIGNS; SMALL-MOLECULE DRUGS;

ESCHERICHIA COLI;

QUALITY CONTROL;

CELL ORGANELLE; COLIFORM BACTERIUM; CULTIVATION; DRUG; MAMMAL; MANUFACTURING; MOLECULAR ANALYSIS; MONITORING; SOFTWARE; YEAST;

BIOREACTOR; CALORIMETRY; COMPUTER PROGRAM; DIELECTRIC SPECTROMETRY; DRUG INDUSTRY; ESCHERICHIA COLI; FLOW CYTOMETRY; FLUORESCENCE SPECTROSCOPY; HEALTH CARE QUALITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MAMMAL CELL; MASS SPECTROMETRY; MEDICAL TECHNOLOGY; MICROARRAY ANALYSIS; NEAR INFRARED SPECTROSCOPY; PHARMACOLOGICAL PARAMETERS; PHOTOACOUSTIC SPECTROSCOPY; PROCESS ANALYTICAL TECHNOLOGY; RAMAN SPECTROMETRY; REVIEW; SYNTHESIS; TABLET; ULTRAVIOLET SPECTROSCOPY; YEAST;

ESCHERICHIA COLI; MAMMALIA;

EID: 84877013068     PISSN: 16180240     EISSN: 16182863     Source Type: Journal    
DOI: 10.1002/elsc.201200025     Document Type: Review

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