Flux balance analysis of CHO cells before and after a metabolic switch from lactate production to consumption

Biotechnology and Bioengineering

Volumn 110, Issue 2, 2013, Pages 660-666

  Martínez, Verónica S ^a   Dietmair, Stefanie ^a   Quek, Lake Ee ^a   Hodson, Mark P ^a   Gray, Peter ^a   Nielsen, Lars K ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

CHO cells; Energy metabolism; Flux balance analysis; Lactate metabolism; Metabolic switch

Indexed keywords

CHINESE HAMSTER OVARY CELLS; CHO CELL; CONCOMITANT PRODUCTION; DEGREE OF FREEDOM; ENERGY EFFICIENT; ENERGY METABOLISM; FLUX BALANCE ANALYSIS; FLUX RANGES; GLUCOSE DEPLETION; MAMMALIAN CELL CULTURE; MAMMALIAN CELLS; METABOLIC CHANGES; METABOLIC MODELS; MOUSE GENOME; TCA CYCLE;

CELL CULTURE; CELLS; ENERGY EFFICIENCY; GLUCOSE;

METABOLISM;

ADENOSINE TRIPHOSPHATE; LACTIC ACID;

ANALYSIS; ANIMAL CELL; ARTICLE; ENERGY METABOLISM; FLUX BALANCE ANALYSIS; MEASUREMENT; NONHUMAN; OVARY CELL; PROCEDURES;

ADENOSINE TRIPHOSPHATE; ANIMALS; CELL PROLIFERATION; CELL SURVIVAL; CHO CELLS; CRICETINAE; CRICETULUS; ENERGY METABOLISM; GLUCOSE; INTRACELLULAR SPACE; LACTIC ACID; METABOLIC NETWORKS AND PATHWAYS; MODELS, BIOLOGICAL; SYSTEMS BIOLOGY;

CRICETULUS GRISEUS; MAMMALIA;

EID: 84871722305     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.24728     Document Type: Article

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