PAT for vaccines: The first stage of PAT implementation for development of a well-defined whole-cell vaccine against whooping cough disease

Vaccine

Volumn 25, Issue 16 SPEC. ISS., 2007, Pages 2994-3000

  Streefland, Mathieu ^a   van de Waterbeemd, Bas ^a   Happé, Hester ^b   van der Pol, Leo A ^a   Beuvery, E Coen ^c   Tramper, Johannes ^d   Martens, Dirk E ^d  

^a NETHERLANDS VACCINE INSTITUTE   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c PAT Consultancy   (Netherlands)

^d WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Bioreactor; Bordetella pertussis; Cultivation; Microarray; Process Analytical Technology; Product quality; Virulence

Indexed keywords

VACCINE;

ANALYTIC METHOD; ANIMAL TESTING ALTERNATIVE; ARTICLE; BACTERIAL VIRULENCE; BACTERIUM CULTURE; BORDETELLA PERTUSSIS; CELL FUNCTION; CONTROLLED STUDY; DNA MICROARRAY; DRUG QUALITY; ELIMINATION REACTION; MARKER GENE; MEASUREMENT; NONHUMAN; PERTUSSIS; PRIORITY JOURNAL; WHOLE CELL;

EID: 33947601746     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2007.01.015     Document Type: Article

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