Case study and application of process analytical technology (PAT) towards bioprocessing: II. Use of ultra-performance liquid chromatography (UPLC) for making real-time pooling decisions for process chromatography

Biotechnology and Bioengineering

Volumn 101, Issue 6, 2008, Pages 1366-1374

  Rathore, Anurag S ^a   Wood, Rebecca ^b   Sharma, Ashutosh ^a   Dermawan, Shinta ^a  

^a AMGEN INC   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Design space; PAT; Process analytical technology; Ultraperformance liquid chromatography; UPLC

Indexed keywords

APPLICATIONS; BODY FLUIDS; CHEMICAL SENSORS; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; COLUMN CHROMATOGRAPHY; COLUMNS (STRUCTURAL); HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; PROCESS ENGINEERING; QUALITY ASSURANCE; QUALITY CONTROL; TOTAL QUALITY MANAGEMENT;

DESIGN SPACE; PAT; PROCESS ANALYTICAL TECHNOLOGY; ULTRAPERFORMANCE LIQUID CHROMATOGRAPHY; UPLC;

LIQUID CHROMATOGRAPHY;

ARTICLE; BIOPROCESS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTERMETHOD COMPARISON; PROCESS ANALYTICAL TECHNOLOGY; PROCESS DESIGN; PROCESS DEVELOPMENT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; REVERSED PHASE ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

CHROMATOGRAPHY, LIQUID; DRUG INDUSTRY; QUALITY ASSURANCE, HEALTH CARE;

EID: 56749109512     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.21982     Document Type: Article

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