메뉴 건너뛰기




Volumn 36, Issue 5, 2013, Pages 517-530

Accelerating animal cell growth in perfusion mode by multivariable control: Simulation studies

Author keywords

Bioprocess; Hybridoma; Model predictive control; Optimization

Indexed keywords

BIOPROCESSES; CONTINUOUS CULTURE; HYBRIDOMA; HYBRIDOMA CELLS; MULTIVARIABLE CONTROL; SELF ADAPTIVE CONTROL; SIMULATION STUDIES; STEADY STATE SOLUTION;

EID: 84877925766     PISSN: 16157591     EISSN: 16157605     Source Type: Journal    
DOI: 10.1007/s00449-012-0807-0     Document Type: Article
Times cited : (11)

References (22)
  • 1
    • 78650525718 scopus 로고    scopus 로고
    • Dynamic model of CHO cell metabolism
    • 10.1016/j.ymben.2010.09.003
    • Nolan RP, Lee K (2011) Dynamic model of CHO cell metabolism. Metab Eng 3:108-124
    • (2011) Metab Eng , vol.3 , pp. 108-124
    • Nolan, R.P.1    Lee, K.2
  • 2
    • 45849133763 scopus 로고    scopus 로고
    • Mouse monoclonal antibodies in biological research: Strategies for high-throughput production
    • 10.1007/s10529-008-9706-5 1:CAS:528:DC%2BD1cXnsVCrtro%3D
    • Chiarella P, Fazio VM (2008) Mouse monoclonal antibodies in biological research: strategies for high-throughput production. Biotechnol Lett 30:1303-1310
    • (2008) Biotechnol Lett , vol.30 , pp. 1303-1310
    • Chiarella, P.1    Fazio, V.M.2
  • 3
    • 0033952514 scopus 로고    scopus 로고
    • Improvement of CHO cell culture medium formulation: Simultaneous substitution of glucose and glutamine
    • 10.1021/bp990124j 1:CAS:528:DyaK1MXnsFOms74%3D
    • Altamirano C, Paredes C, Cairo JJ, Godia F (2000) Improvement of CHO cell culture medium formulation: simultaneous substitution of glucose and glutamine. Biotechnol Prog 16:69-75
    • (2000) Biotechnol Prog , vol.16 , pp. 69-75
    • Altamirano, C.1    Paredes, C.2    Cairo, J.J.3    Godia, F.4
  • 5
    • 36248985213 scopus 로고    scopus 로고
    • Upstream processes in antibody production: Evaluation of critical parameters
    • 10.1016/j.biotechadv.2007.09.004 1:CAS:528:DC%2BD2sXhtlGnsrfP
    • Jain E, Kumar A (2008) Upstream processes in antibody production: evaluation of critical parameters. Biotechnol Adv 26:46-72
    • (2008) Biotechnol Adv , vol.26 , pp. 46-72
    • Jain, E.1    Kumar, A.2
  • 6
    • 77954865091 scopus 로고    scopus 로고
    • Comparative production of a monoclonal antibody specific for enrofloxacin in a stirred-tank bioreactor
    • 10.1016/j.jiec.2010.03.018 1:CAS:528:DC%2BC3cXnt1Gnu78%3D
    • Komolpis K, Udomchokmongkol C, Phutong S, Palaga T (2010) Comparative production of a monoclonal antibody specific for enrofloxacin in a stirred-tank bioreactor. J Ind Eng Chem 16:567-571
    • (2010) J Ind Eng Chem , vol.16 , pp. 567-571
    • Komolpis, K.1    Udomchokmongkol, C.2    Phutong, S.3    Palaga, T.4
  • 7
    • 0029360347 scopus 로고
    • Partial and total cell retention in a filtration base homogeneous perfusion reactor
    • 10.1021/bp00035a013 1:CAS:528:DyaK2MXotVChu7c%3D
    • Banik GG, Heath CA (1995) Partial and total cell retention in a filtration base homogeneous perfusion reactor. Biotechnol Prog 11:584-588
    • (1995) Biotechnol Prog , vol.11 , pp. 584-588
    • Banik, G.G.1    Heath, C.A.2
  • 8
    • 10644291524 scopus 로고    scopus 로고
    • Effect of feed and bleed rate on hybridoma cells in an acoustic perfusion bioreactor: Part 1. Cell density, viability and cell-cycle distribution
    • 10.1002/bit.20287 1:CAS:528:DC%2BD2cXhtVCjt7nI
    • Dalm M, Cuijten S, van Grunsven W, Tramper J, Martens D (2004) Effect of feed and bleed rate on hybridoma cells in an acoustic perfusion bioreactor: Part 1. Cell density, viability and cell-cycle distribution. Biotechnol Bioeng 88:547-557
    • (2004) Biotechnol Bioeng , vol.88 , pp. 547-557
    • Dalm, M.1    Cuijten, S.2    Van Grunsven, W.3    Tramper, J.4    Martens, D.5
  • 9
    • 0034688445 scopus 로고    scopus 로고
    • Understanding factors that limit the productivity of suspension-based perfusion cultures operated at high medium renewal rates
    • 10.1002/(SICI)1097-0290(20000220)67:4<435: AID-BIT7>3.0.CO;2-Y 1:CAS:528:DC%2BD3cXntFKmuw%3D%3D
    • Mercille S, Johnson M, Lanthier S, Kamen AA, Massie B (2000) Understanding factors that limit the productivity of suspension-based perfusion cultures operated at high medium renewal rates. Biotechnol Bioeng 67:435-449
    • (2000) Biotechnol Bioeng , vol.67 , pp. 435-449
    • Mercille, S.1    Johnson, M.2    Lanthier, S.3    Kamen, A.A.4    Massie, B.5
  • 10
    • 0034609009 scopus 로고    scopus 로고
    • Achievment of high cell density and high antibody productivity by a controlled-fed perfusion bioreactor process
    • 10.1002/(SICI)1097-0290(20000705)69:1<74: AID-BIT9>3.0.CO;2-K 1:CAS:528:DC%2BD3cXkt1Wrt7Y%3D
    • Yang JD, Angelillo Y, Chaudhry M, Goldenberg C, Goldenberg DM (2000) Achievment of high cell density and high antibody productivity by a controlled-fed perfusion bioreactor process. Biotechnol Bioeng 69:74-82
    • (2000) Biotechnol Bioeng , vol.69 , pp. 74-82
    • Yang, J.D.1    Angelillo, Y.2    Chaudhry, M.3    Goldenberg, C.4    Goldenberg, D.M.5
  • 11
    • 0342547017 scopus 로고    scopus 로고
    • Real-time monitoring and control of glucose and lactate concentrations in a mammalian cell perfusion reactor
    • 10.1002/(SICI)1097-0290(19970220)53:4<372: AID-BIT3>3.0.CO;2-K 1:CAS:528:DyaK2sXhtV2jsLk%3D
    • Ozturk SS, Thrift JC, Blackie JD, Naveh D (1997) Real-time monitoring and control of glucose and lactate concentrations in a mammalian cell perfusion reactor. Biotechnol Bioeng 53:372-378
    • (1997) Biotechnol Bioeng , vol.53 , pp. 372-378
    • Ozturk, S.S.1    Thrift, J.C.2    Blackie, J.D.3    Naveh, D.4
  • 12
    • 34047181427 scopus 로고    scopus 로고
    • Use of cell bleed in a high cell density perfusion culture and multivariable control of biomass and metabolite concentrations
    • 10.1002/apj.10
    • Deschênes J-S, Desbiens A, Perrier M, Kamen A (2006) Use of cell bleed in a high cell density perfusion culture and multivariable control of biomass and metabolite concentrations. Asia-Pac J Chem Eng 1:82-91
    • (2006) Asia-Pac J Chem Eng , vol.1 , pp. 82-91
    • Deschênes, J.-S.1    Desbiens, A.2    Perrier, M.3    Kamen, A.4
  • 13
    • 33846239237 scopus 로고    scopus 로고
    • Multivariable nonlinear control of biomass and metabolite concentrations in a high-cell-density perfusion bioreactor
    • 10.1021/ie060582e
    • Deschênes J-S, Desbiens A, Perrier M, Kamen A (2006) Multivariable nonlinear control of biomass and metabolite concentrations in a high-cell-density perfusion bioreactor. Ind Eng Chem Res 45:8985-8997
    • (2006) Ind Eng Chem Res , vol.45 , pp. 8985-8997
    • Deschênes, J.-S.1    Desbiens, A.2    Perrier, M.3    Kamen, A.4
  • 17
    • 77954549854 scopus 로고    scopus 로고
    • Invited chapter in UNESCO Encyclopedia of Life Support Systems (EoLSS), article 6.43.16.1, vol 83. Eolss Publishers, Oxford
    • De Keyser RMC (2003) Model based predictive control. Invited chapter in UNESCO Encyclopedia of Life Support Systems (EoLSS), article 6.43.16.1, vol 83. Eolss Publishers, Oxford
    • (2003) Model Based Predictive Control
    • De Keyser, R.M.C.1
  • 18
    • 0026542004 scopus 로고
    • Optimization of fed-batch culture of hybridoma cells using dynamic programming: Single and multi feed cases
    • de Tremblay M, Perrier M, Chavarie C, Archambault J (1992) Optimization of fed-batch culture of hybridoma cells using dynamic programming: single and multi feed cases. Bioprocess Eng 7:229-234
    • (1992) Bioprocess Eng , vol.7 , pp. 229-234
    • De Tremblay, M.1    Perrier, M.2    Chavarie, C.3    Archambault, J.4
  • 20
    • 78649444102 scopus 로고    scopus 로고
    • Steady state multiplicity of two-step biological conversion systems with general kinetics
    • 10.1016/j.mbs.2010.09.004 1:STN:280:DC%2BC3cbotl2ltg%3D%3D
    • Volcke EIP, Sbarciog M, Noldus EJL, De Baets B, Loccufier M (2010) Steady state multiplicity of two-step biological conversion systems with general kinetics. Math Biosci 228:160-170
    • (2010) Math Biosci , vol.228 , pp. 160-170
    • Volcke, E.I.P.1    Sbarciog, M.2    Noldus, E.J.L.3    De Baets, B.4    Loccufier, M.5
  • 21
    • 8744230577 scopus 로고    scopus 로고
    • Matcont: A Matlab package for numerical bifurcation analysis of ODEs
    • 10.1145/779359.779362
    • Dhooge A, Govaerts W, Kuznetsov YA (2003) Matcont: A Matlab package for numerical bifurcation analysis of ODEs. ACM Trans Math Softw 29:141-164
    • (2003) ACM Trans Math Softw , vol.29 , pp. 141-164
    • Dhooge, A.1    Govaerts, W.2    Kuznetsov, Y.A.3
  • 22
    • 0035922854 scopus 로고    scopus 로고
    • Glucose-based optimization of CHO-cell perfusion cultures
    • 10.1002/bit.10013 1:CAS:528:DC%2BD3MXnsVeqtrg%3D
    • Dowd JE, Kwok KE, Piret JM (2001) Glucose-based optimization of CHO-cell perfusion cultures. Biotechnol Bioeng 75:252-256
    • (2001) Biotechnol Bioeng , vol.75 , pp. 252-256
    • Dowd, J.E.1    Kwok, K.E.2    Piret, J.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.