메뉴 건너뛰기




Volumn 15, Issue 1, 1999, Pages 81-90

Modeling of overflow metabolism in batch and fed-batch cultures of Escherichia coli

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM CULTURE; GLUCOSE METABOLISM; MODEL;

EID: 0033047059     PISSN: 87567938     EISSN: None     Source Type: Journal    
DOI: 10.1021/bp9801087     Document Type: Article
Times cited : (186)

References (43)
  • 1
    • 0001594470 scopus 로고
    • Regulation of α-Ketoglutarate dehydrogenase formation in Escherichia coli
    • Amarasingham, C. R.; Davis, B. D. Regulation of α-Ketoglutarate Dehydrogenase Formation in Escherichia coli. J. Biol. Chem. 1965, 240, 3664-3668.
    • (1965) J. Biol. Chem. , vol.240 , pp. 3664-3668
    • Amarasingham, C.R.1    Davis, B.D.2
  • 2
    • 0019132335 scopus 로고
    • Are growth rates of Escherichia coli in batch cultures limited by respiration?
    • Andersen, K. B.; von Meyenburg, K. Are Growth Rates of Escherichia coli in Batch Cultures Limited by Respiration? J. Bacteriol. 1980, 144, 114-123.
    • (1980) J. Bacteriol. , vol.144 , pp. 114-123
    • Andersen, K.B.1    Von Meyenburg, K.2
  • 4
    • 0030088492 scopus 로고    scopus 로고
    • Cell segregation and lysis have profound effects on the growth of Escherichia coli in high cell density fed batch cultures
    • Andersson, L.; Strandberg, L.; Enfors, S.-O. Cell Segregation and Lysis Have Profound Effects on the Growth of Escherichia coli in High Cell Density Fed Batch Cultures. Biotechnol. Prog. 1996, 12, 190-195.
    • (1996) Biotechnol. Prog. , vol.12 , pp. 190-195
    • Andersson, L.1    Strandberg, L.2    Enfors, S.-O.3
  • 5
    • 0029636672 scopus 로고
    • Transport of lactate and acetate through the energized cytoplasmic membrane of Escherichia coli
    • Axe, D. D.; Bailey, J. E. Transport of Lactate and Acetate Through the Energized Cytoplasmic Membrane of Escherichia coli. Biotechnol. Bioeng. 1995, 47, 8-19.
    • (1995) Biotechnol. Bioeng. , vol.47 , pp. 8-19
    • Axe, D.D.1    Bailey, J.E.2
  • 6
    • 0023521883 scopus 로고
    • Control of bacterial fermentation
    • Bajpai, R. Control of Bacterial Fermentation. Ann. N. Y. Acad. Sci. 1987, 506, 446-458.
    • (1987) Ann. N. Y. Acad. Sci. , vol.506 , pp. 446-458
    • Bajpai, R.1
  • 7
    • 0345056606 scopus 로고
    • Extracellular metabolic products of Escherichia coli during rapid growth
    • Britten, R. Extracellular Metabolic Products of Escherichia coli During Rapid Growth. Science 1954, 119, 578.
    • (1954) Science , vol.119 , pp. 578
    • Britten, R.1
  • 8
    • 0017759929 scopus 로고
    • The enzymatic interconversion of acetate and acetyl-coenzyme A in Escherichia coli
    • Brown, T. D. K.; Jones-Mortimer, M. C.; Kornberg, H. L. The Enzymatic Interconversion of Acetate and Acetyl-coenzyme A in Escherichia coli. J. Gen. Microbiol. 1977, 102, 327-336.
    • (1977) J. Gen. Microbiol. , vol.102 , pp. 327-336
    • Brown, T.D.K.1    Jones-Mortimer, M.C.2    Kornberg, H.L.3
  • 9
    • 0022251874 scopus 로고
    • Continuous production of human leukocyte interferon with Escherichia coli and continuous cell lysis in a two stage chemostat
    • Brown, S. W.; Meyer, H.; Fiechter, A. Continuous Production of Human Leukocyte Interferon with Escherichia coli and Continuous Cell Lysis in a Two Stage Chemostat. Appl. Microbiol. Biotechnol. 1985, 23, 5-9.
    • (1985) Appl. Microbiol. Biotechnol. , vol.23 , pp. 5-9
    • Brown, S.W.1    Meyer, H.2    Fiechter, A.3
  • 10
    • 0031555498 scopus 로고    scopus 로고
    • Comparative studies of Escherichia coli strains using different glucose uptake systems: Metabolism and energetics
    • Chen, R.; Yap, W. M. G. J.; Postma, P. W.; Bailey, J. E. Comparative Studies of Escherichia coli Strains Using Different Glucose Uptake Systems: Metabolism and Energetics. Biotechnol. Bioeng. 1997, 56, 583-590.
    • (1997) Biotechnol. Bioeng. , vol.56 , pp. 583-590
    • Chen, R.1    Yap, W.M.G.J.2    Postma, P.W.3    Bailey, J.E.4
  • 11
    • 0028535143 scopus 로고
    • Effect of modulated glucose uptake on high-level recombinant protein production in a dense Escherichia coli culture
    • Chou, C. H.; Bennett, G. N.; San, K. Y. Effect of Modulated Glucose Uptake on High-Level Recombinant Protein Production in a Dense Escherichia Coli Culture. Biotechnol. Prog. 1994, 10, 644-647.
    • (1994) Biotechnol. Prog. , vol.10 , pp. 644-647
    • Chou, C.H.1    Bennett, G.N.2    San, K.Y.3
  • 12
    • 0000146513 scopus 로고    scopus 로고
    • Neidhardt, F. C., Curtiss, R., III, Ingraham, J. L., Lin, E. C. C., Low, K. B., Magasanik, B., Reznikoff, W. S., Riley, M., Schaechter, M., Umbarger, H. E., Eds.; ASM Press: Washington, DC
    • Clark, D. P.; Cronan, J. E., Jr. In Escherichia coli and Salmonella: Cellular and Molecular Biology; Neidhardt, F. C., Curtiss, R., III, Ingraham, J. L., Lin, E. C. C., Low, K. B., Magasanik, B., Reznikoff, W. S., Riley, M., Schaechter, M., Umbarger, H. E., Eds.; ASM Press: Washington, DC, 1996; pp 343-357.
    • (1996) Escherichia Coli and Salmonella: Cellular and Molecular Biology , pp. 343-357
    • Clark, D.P.1    Cronan J.E., Jr.2
  • 13
    • 0024691816 scopus 로고
    • Chemostat study of kinetics of human lymphokine synthesis in recombinant Escherichia coli
    • Curless, C. E.; Forrer, P. D.; Mann, M. B.; Fenton, D. M.; Tsai, L. B. Chemostat Study of Kinetics of Human Lymphokine Synthesis in Recombinant Escherichia coli. Biotechnol. Bioeng. 1989, 34, 415-421.
    • (1989) Biotechnol. Bioeng. , vol.34 , pp. 415-421
    • Curless, C.E.1    Forrer, P.D.2    Mann, M.B.3    Fenton, D.M.4    Tsai, L.B.5
  • 14
  • 15
    • 0024416873 scopus 로고
    • Control of carbon flux to acetate excretion during growth of Escherichia coli in batch and continuous cultures
    • El-Mansi, E. M. T.; Holms, W. H. Control of Carbon Flux to Acetate Excretion During Growth of Escherichia Coli in Batch and Continuous Cultures. J. Gen. Microbiol. 1989, 135, 2875-2883.
    • (1989) J. Gen. Microbiol. , vol.135 , pp. 2875-2883
    • El-Mansi, E.M.T.1    Holms, W.H.2
  • 16
    • 0028290762 scopus 로고
    • Steady-state modelling of metabolic flux between the tricarboxylic acid cycle and the glyoxylate bypass in Escherichia coli
    • El-Mansi, E. M.; Dawson, G. C.; Bryce, C. F. Steady-State Modelling of Metabolic Flux Between the Tricarboxylic Acid Cycle and the Glyoxylate Bypass in Escherichia coli. Comput. Appl. Biosci. 1994, 10, 295-299.
    • (1994) Comput. Appl. Biosci. , vol.10 , pp. 295-299
    • El-Mansi, E.M.1    Dawson, G.C.2    Bryce, C.F.3
  • 17
    • 0030853330 scopus 로고    scopus 로고
    • Reduction of aerobic acetate production by Escherichia coli
    • Farmer, W. R.; Liao, J. C. Reduction of Aerobic Acetate Production by Escherichia coli. Appl. Environ. Microbiol. 1997, 63, 3205-3210.
    • (1997) Appl. Environ. Microbiol. , vol.63 , pp. 3205-3210
    • Farmer, W.R.1    Liao, J.C.2
  • 19
    • 0014030357 scopus 로고
    • Regulation of metabolism in facultative bacteria. II. Effects of aerobiosis, anaerobiosis and nutrition on the formation of krebs cycle enzymes in Escherichia coli
    • Gray, C. T.; Wimpenny, J. W. T.; Mossman, M. R. Regulation of Metabolism in Facultative Bacteria. II. Effects of Aerobiosis, Anaerobiosis and Nutrition on the Formation of Krebs Cycle Enzymes in Escherichia coli. Biochim. Biophys. Acta 1966, 117, 33-41.
    • (1966) Biochim. Biophys. Acta , vol.117 , pp. 33-41
    • Gray, C.T.1    Wimpenny, J.W.T.2    Mossman, M.R.3
  • 20
    • 0026832754 scopus 로고
    • Acetic acid formation in Escherichia coli fermentation
    • Han, K.; Lim, H. C.; Hong, J. Acetic Acid Formation in Escherichia coli Fermentation. Biotechnol. Bioeng. 1992, 39, 663-671.
    • (1992) Biotechnol. Bioeng. , vol.39 , pp. 663-671
    • Han, K.1    Lim, H.C.2    Hong, J.3
  • 21
    • 0017208520 scopus 로고
    • Effect of specific growth rate and glucose concentration on growth and glucose metabolism of Escherichia coli K12
    • Hollywood, N.; Doelle, H. W. Effect of Specific Growth Rate and Glucose Concentration on Growth and Glucose Metabolism of Escherichia coli K12. Microbios 1976, 17, 23-33.
    • (1976) Microbios , vol.17 , pp. 23-33
    • Hollywood, N.1    Doelle, H.W.2
  • 22
    • 0022985811 scopus 로고
    • The central metabolic pathways of Escherichia coli: Relationship between flux and control at a branch point, efficiency of conversion to biomass, and excretion of acetate
    • Holms, W. H. The Central Metabolic Pathways of Escherichia coli: Relationship Between Flux and Control at a Branch Point, Efficiency of Conversion to Biomass, and Excretion of Acetate. Curr. Top. Cell. Regul. 1986, 28, 69-105.
    • (1986) Curr. Top. Cell. Regul. , vol.28 , pp. 69-105
    • Holms, W.H.1
  • 23
    • 0030463296 scopus 로고    scopus 로고
    • Flux analysis and control of the central metabolic pathways in Escherichia coli
    • Holms, H. Flux Analysis and Control of the Central Metabolic Pathways in Escherichia coli. FEMS Microbiol. Rev. 1996, 19, 85-116.
    • (1996) FEMS Microbiol. Rev. , vol.19 , pp. 85-116
    • Holms, H.1
  • 24
    • 0021144978 scopus 로고
    • The respiratory chains of Escherichia coli
    • Ingledew, W. J.; Poole, R. K. The Respiratory Chains of Escherichia coli. Microbiol. Rev. 1984, 48, 222-271.
    • (1984) Microbiol. Rev. , vol.48 , pp. 222-271
    • Ingledew, W.J.1    Poole, R.K.2
  • 25
    • 0028052113 scopus 로고
    • Acetate metabolism by Escherichia coli in high cell density fermentation
    • Kleman, G. L.; Strohl, W. R. Acetate Metabolism by Escherichia coli in High Cell Density Fermentation. Appl. Environ. Microbiol. 1994, 57, 3952-3958.
    • (1994) Appl. Environ. Microbiol. , vol.57 , pp. 3952-3958
    • Kleman, G.L.1    Strohl, W.R.2
  • 26
    • 0027656389 scopus 로고
    • An integrated metabolic modeling approach to describe the energy efficiency of Escherichia coli fermentations under oxygen limited conditions, cellular energetics, carbon flux, and acetate production
    • Ko, Y.-F.; Bentley, W. E.; Weignand, W. A. An Integrated Metabolic Modeling Approach to Describe the Energy Efficiency of Escherichia coli Fermentations Under Oxygen Limited Conditions, Cellular Energetics, Carbon Flux, and Acetate Production. Biotechnol. Bioeng. 1993, 42, 843-853.
    • (1993) Biotechnol. Bioeng. , vol.42 , pp. 843-853
    • Ko, Y.-F.1    Bentley, W.E.2    Weignand, W.A.3
  • 27
    • 0028418575 scopus 로고
    • A metabolic model of cellular energetics and carbon flux during aerobic E. coli fermentation
    • Ko, Y.-F.; Bentley, W. E.; Weigand, W. A. A Metabolic Model of Cellular Energetics and Carbon Flux During Aerobic E. coli Fermentation. Biotechnol. Bioeng. 1994, 43, 847-855.
    • (1994) Biotechnol. Bioeng. , vol.43 , pp. 847-855
    • Ko, Y.-F.1    Bentley, W.E.2    Weigand, W.A.3
  • 28
    • 0025701081 scopus 로고
    • A balanced DO-stat and its application to the control of acetic acid excretion by recombinant Escherichia coli
    • Konstantinov, K.; Kishimoto, M.; Seki, T.; Yoshida, T. A Balanced DO-Stat and Its Application to the Control of Acetic Acid Excretion by Recombinant Escherichia coli. Biotechnol. Bioeng. 1990, 36, 750-758.
    • (1990) Biotechnol. Bioeng. , vol.36 , pp. 750-758
    • Konstantinov, K.1    Kishimoto, M.2    Seki, T.3    Yoshida, T.4
  • 29
    • 0029874193 scopus 로고    scopus 로고
    • High cell-density culture of Escherichia coli
    • Lee, S. Y. High Cell-Density Culture of Escherichia coli. Trends Biotechnol. 1996, 14, 98-105.
    • (1996) Trends Biotechnol. , vol.14 , pp. 98-105
    • Lee, S.Y.1
  • 30
    • 0025264582 scopus 로고
    • Comparison of growth, acetate production, and acetate inhibition of Escherichia Coli strains in batch and fed-batch fermentations
    • Luli, G. W.; Strohl, W. R. Comparison of Growth, Acetate Production, and Acetate Inhibition of Escherichia Coli Strains in Batch and Fed-Batch Fermentations. Appl. Environ. Microbiol. 1990, 56, 1004-1011.
    • (1990) Appl. Environ. Microbiol. , vol.56 , pp. 1004-1011
    • Luli, G.W.1    Strohl, W.R.2
  • 31
    • 0025405421 scopus 로고
    • Simple constrained-optimization view of acetate overflow in E. coli
    • Majewski, R. A.; Domach, M. M. Simple Constrained-Optimization View of Acetate Overflow in E. coli. Biotechnol. Bioeng. 1990, 35, 732-738.
    • (1990) Biotechnol. Bioeng. , vol.35 , pp. 732-738
    • Majewski, R.A.1    Domach, M.M.2
  • 32
    • 0021750544 scopus 로고
    • Acetate formation in continuous culture of Escherichia coli K12D1 on defined and complex media
    • Meyer, H.; Leist, C.; Fiechter, A. Acetate Formation in Continuous Culture of Escherichia coli K12D1 on Defined and Complex Media. J. Biotechnol. 1984, 1, 355-358.
    • (1984) J. Biotechnol. , vol.1 , pp. 355-358
    • Meyer, H.1    Leist, C.2    Fiechter, A.3
  • 33
    • 0027323041 scopus 로고
    • Isolation and properties of a mutant of Escherichia coli with an insertional inactivation of the uspA gene, which encodes a universal stress protein
    • Nyström, T.; Neidhardt, F. C. Isolation and Properties Of a Mutant of Escherichia coli With an Insertional Inactivation of the uspA Gene, Which Encodes a Universal Stress Protein. J. Bacteriol. 1993, 175, 3949-3956.
    • (1993) J. Bacteriol. , vol.175 , pp. 3949-3956
    • Nyström, T.1    Neidhardt, F.C.2
  • 34
    • 0030948414 scopus 로고    scopus 로고
    • The growth rate control in Escherichia coli at near to maximum growth rates, the A-stat approach
    • Paalme, T.; Elken R.; Kahru, A.; Vanatalu, K.; Vilu, R. The Growth Rate Control in Escherichia coli at near to Maximum Growth Rates, the A-Stat Approach. Antonie van Leeuwenhoek 1997, 71, 217-230.
    • (1997) Antonie van Leeuwenhoek , vol.71 , pp. 217-230
    • Paalme, T.1    Elken, R.2    Kahru, A.3    Vanatalu, K.4    Vilu, R.5
  • 35
    • 0023102352 scopus 로고
    • Physiological constrains in increasing biomass concentration of Escherichia coli B in fed-batch culture
    • Pan, J. G.; Rhee, J. S.; Lebeault, J. M. Physiological Constrains in Increasing Biomass Concentration of Escherichia coli B in Fed-Batch Culture. Biotechnol. Lett. 1987, 9, 89-94.
    • (1987) Biotechnol. Lett. , vol.9 , pp. 89-94
    • Pan, J.G.1    Rhee, J.S.2    Lebeault, J.M.3
  • 36
    • 0032553509 scopus 로고    scopus 로고
    • Growth and energy metabolism in aerobic fed-batch cultures of Saccharomyces cerevisiae: Simulation and model verification
    • Pham, H. T. B.; Larsson, G.; Enfors, S.-O. Growth and Energy Metabolism in Aerobic Fed-Batch Cultures of Saccharomyces cerevisiae: Simulation and Model Verification. Biotechnol. Bioeng. 1998, 60, 474-482.
    • (1998) Biotechnol. Bioeng. , vol.60 , pp. 474-482
    • Pham, H.T.B.1    Larsson, G.2    Enfors, S.-O.3
  • 37
    • 0017124382 scopus 로고
    • The bacterial phosphoenolpyruvate-sugar phosphotransferase system
    • Postman, P. W.; Roseman, S. The Bacterial Phosphoenolpyruvate-Sugar Phosphotransferase System. Biochim. Biophys. Acta 1976, 457, 213-257.
    • (1976) Biochim. Biophys. Acta , vol.457 , pp. 213-257
    • Postman, P.W.1    Roseman, S.2
  • 38
    • 0029133195 scopus 로고
    • Flux analysis of microbial metabolic pathways using a visual programming environment
    • Regan, L.; Gregory, M. Flux Analysis of Microbial Metabolic Pathways Using a Visual Programming Environment. J. Biotechnol. 1995, 42, 151-161.
    • (1995) J. Biotechnol. , vol.42 , pp. 151-161
    • Regan, L.1    Gregory, M.2
  • 39
    • 0019456997 scopus 로고
    • Change in intracellular pH of Escherichia coli mediates the chemotactic response to certain attractants and repellents
    • Repaske, D. R.; Adler, J. Change in Intracellular pH Of Escherichia coli Mediates the Chemotactic Response to Certain Attractants and Repellents. J. Bacteriol. 1981, 145, 1196-1208.
    • (1981) J. Bacteriol. , vol.145 , pp. 1196-1208
    • Repaske, D.R.1    Adler, J.2
  • 40
    • 0019851036 scopus 로고
    • Physical mechanism for regulation of phosphoenolpyruvate-dependent glucose transport activity in Escherichia coli
    • Robillard, G. T.; Konings, W. N. Physical Mechanism for Regulation of Phosphoenolpyruvate-Dependent Glucose Transport Activity in Escherichia coli. Biochemistry 1981, 20, 5025-5032.
    • (1981) Biochemistry , vol.20 , pp. 5025-5032
    • Robillard, G.T.1    Konings, W.N.2
  • 41
    • 0022736565 scopus 로고
    • Growth of Saccharomyces cerevisiae is controlled by its limited respiratory capacity, formulation and verification of a hypothesis
    • Sonnleitner, B.; Käppeli, O. Growth of Saccharomyces cerevisiae Is Controlled by Its Limited Respiratory Capacity, Formulation and Verification of a Hypothesis. Biotechnol. Bioeng. 1986, 28, 927-937.
    • (1986) Biotechnol. Bioeng. , vol.28 , pp. 927-937
    • Sonnleitner, B.1    Käppeli, O.2
  • 43
    • 0028146781 scopus 로고
    • Stoichiometric flux balance models quantitatively predict growth and metabolic by-product secretion in wild-type Escherichia coli W3110
    • Varma, A.; Palsson, B. O. Stoichiometric Flux Balance Models Quantitatively Predict Growth and Metabolic By-Product Secretion in Wild-Type Escherichia coli W3110. Appl. Environ. Microbiol. 1994, 60, 3724-3731.
    • (1994) Appl. Environ. Microbiol. , vol.60 , pp. 3724-3731
    • Varma, A.1    Palsson, B.O.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.