Mammalian cell culture scale-up and fed-batch control using automated flow cytometry

Journal of Biotechnology

Volumn 135, Issue 2, 2008, Pages 174-180

  Sitton, Greg ^a,b   Srienc, Friedrich ^a,b  

^a University of Minnesota   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Automated flow cytometry; Bioreactor monitoring; Mammalian cell culture; PAT initiative; Process Analytical Technology; Single cell heterogeneity

Indexed keywords

CELL CULTURE; CELL PROLIFERATION; FLOW CYTOMETRY; GROWTH KINETICS;

AUTOMATED FLOW CYTOMETRY; FED-BATCH ADDITIONS; STATIONARY PHASE;

BIOREACTORS;

ANALYTIC METHOD; ANIMAL CELL; ARTICLE; CELL COUNT; CELL CULTURE; CELL EXPANSION; CELL GROWTH; CELL POPULATION; CELL PROLIFERATION; CHO CELL; CONTROLLED STUDY; DATA ANALYSIS; FED BATCH CULTURE; FEMALE; FLOW CYTOMETRY; FOOD AND DRUG ADMINISTRATION; KNOWLEDGE BASE; MAMMAL CELL; NONHUMAN; PREDICTION; PRIORITY JOURNAL; QUALITY CONTROL; SCALE UP;

ANIMALS; BIOREACTORS; CELL CULTURE TECHNIQUES; CHO CELLS; CRICETINAE; CRICETULUS; FLOW CYTOMETRY; REPRODUCIBILITY OF RESULTS;

MAMMALIA;

EID: 43849085943     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2008.03.019     Document Type: Article

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