Polo-like kinase 2 (PLK2) phosphorylates α-synuclein at serine 129 in central nervous system

Journal of Biological Chemistry

Volumn 284, Issue 5, 2009, Pages 2598-2602

  Inglis, Kelly J ^a   Chereau, David ^a   Brigham, Elizabeth F ^a   Chiou, San San ^a   Schöbel, Susanne ^a   Frigon, Normand L ^a   Yu, Mei ^a   Caccavello, Russell J ^a   Nelson, Seth ^a   Motter, Ruth ^a   Wright, Sarah ^a   Chian, David ^a   Santiago, Pamela ^a   Soriano, Ferdie ^a   Ramos, Carla ^a   Powell, Kyle ^a   Goldstein, Jason M ^a,b   Babcock, Michael ^a   Yednock, Ted ^a   Bard, Frederique ^a   Basi, Guriqbal S ^a   Sham, Hing ^a   Chilcote, Tamie J ^a,c   McConlogue, Lisa ^a   Griswold Prenner, Irene ^a   Anderson, John P ^a   more..

^a ELAN PHARMACEUTICALS   (United States)

^b NATIONAL CENTER FOR PREPAREDNESS DETECTION AND CONTROL OF INFECTIOUS DISEASES   (United States)

^c ActiveSite Pharmaceuticals Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BRAIN; CELL CULTURE; NEUROPHYSIOLOGY; PHOSPHORYLATION;

BIOCHEMICAL ASSAY; CENTRAL NERVOUS SYSTEMS; CORTICAL CELLS; NEUROLOGICAL DISEASE; PARKINSON DISEASE; POLO-LIKE KINASE; SERUM-INDUCIBLE KINASE; SHORT HAIRPIN RNA;

ENZYMES;

ALPHA SYNUCLEIN; POLO LIKE KINASE 2; SERINE;

ANIMAL TISSUE; ARTICLE; BIOCHEMISTRY; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

EID: 59149090357     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.C800206200     Document Type: Article

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