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Volumn 9, Issue 2, 2000, Pages 179-195

Improving the survival of grafted dopaminergic neurons: A review over current approaches

Author keywords

Cell death; Growth factor; Neuroprotection; Parkinson's disease; Transplantation

Indexed keywords

2 [[4 [2,6 BIS(1 PYRROLIDINYL) 4 PYRIMIDINYL] 1 PIPERAZINYL]METHYL] 3,4 DIHYDRO 2,5,7,8 TETRAMETHYL 2H 1 BENZOPYRAN 6 OL; 2,4 DIAMINOPYRROLOPYRIMIDINE; 21 [4 [2,6 BIS(1 PYRROLIDINYL) 4 PYRIMIDINYL] 1 PIPERAZINYL]PREGNA 1,4,9(11) TRIENE 3,20 DIONE; ADENOSINE TRIPHOSPHATE; BASIC FIBROBLAST GROWTH FACTOR; CALCIUM; CASPASE; CASPASE INHIBITOR; CATALASE; CYTOCHROME C OXIDASE; DIZOCILPINE; DNA FRAGMENT; DOPAMINE; EXCITATORY AMINO ACID; FLUNARIZINE; FREE RADICAL; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GLUTATHIONE PEROXIDASE; GROWTH FACTOR; LAZAROID; NIMODIPINE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHOSPHOLIPASE; PROTEINASE; PYRROLOPYRIMIDINE DERIVATIVE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; TIRILAZAD; TRANSFORMING GROWTH FACTOR BETA; UNINDEXED DRUG;

EID: 0034065380     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.1177/096368970000900205     Document Type: Article
Times cited : (315)

References (151)
  • 1
    • 0032575688 scopus 로고    scopus 로고
    • The Bcl-2 protein family: Arbiters of cell survival
    • Adams, J. M.; Cory, S. The Bcl-2 protein family: Arbiters of cell survival. Science 281:1322-1326; 1998.
    • (1998) Science , vol.281 , pp. 1322-1326
    • Adams, J.M.1    Cory, S.2
  • 2
    • 0024335298 scopus 로고
    • Dihydropyridine-sensitive low-threshold calcium channels in isolated hypothalamic neurones
    • Lond.
    • Akaike, N.; Kostyuk, P. G.; Osipchuk, Y. V. Dihydropyridine-sensitive low-threshold calcium channels in isolated hypothalamic neurones. J. Physiol. (Lond.) 412: 181-195; 1989.
    • (1989) J. Physiol. , vol.412 , pp. 181-195
    • Akaike, N.1    Kostyuk, P.G.2    Osipchuk, Y.V.3
  • 3
    • 0028793257 scopus 로고
    • Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function
    • Ankarcrona, M.; Dypbukt, J. M.; Bonfoco, E.; Zhivotovsky, B.; Orrenius, S.; Lipton, S. A.; Nicotera, P. Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function. Neuron 15:961-973; 1995.
    • (1995) Neuron , vol.15 , pp. 961-973
    • Ankarcrona, M.1    Dypbukt, J.M.2    Bonfoco, E.3    Zhivotovsky, B.4    Orrenius, S.5    Lipton, S.A.6    Nicotera, P.7
  • 4
    • 0031905828 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor improves intrastriatal graft survival of stored dopaminergic cells
    • Apostolides, C.; Sanford, E.; Hong, M.; Mendez, I. Glial cell line-derived neurotrophic factor improves intrastriatal graft survival of stored dopaminergic cells. Neuroscience 83:363-372; 1998.
    • (1998) Neuroscience , vol.83 , pp. 363-372
    • Apostolides, C.1    Sanford, E.2    Hong, M.3    Mendez, I.4
  • 5
    • 0030981722 scopus 로고    scopus 로고
    • Impaired mitochondrial function, oxidative stress and altered antioxidant enzyme activities following traumatic spinal cord injury
    • Azbill, R. D.; Mu, X.; Bruce-Keller, A. J.; Mattson, M. P.; Springer, J. E. Impaired mitochondrial function, oxidative stress and altered antioxidant enzyme activities following traumatic spinal cord injury. Brain Res. 765: 283-290; 1997.
    • (1997) Brain Res. , vol.765 , pp. 283-290
    • Azbill, R.D.1    Mu, X.2    Bruce-Keller, A.J.3    Mattson, M.P.4    Springer, J.E.5
  • 6
    • 0022332721 scopus 로고
    • In vitro studies on the maturation of mesencephalic dopaminergic neurons
    • Barbin, G.; Mallat, M.; Prochiantz, A. In vitro studies on the maturation of mesencephalic dopaminergic neurons. Dev. Neurosci. 7:296-307; 1985.
    • (1985) Dev. Neurosci. , vol.7 , pp. 296-307
    • Barbin, G.1    Mallat, M.2    Prochiantz, A.3
  • 7
    • 0030932056 scopus 로고    scopus 로고
    • Intrastriatal grafts of embryonic mesencephalic rat neurons genetically modified using an adenovirus encoding human Cu/Zn superoxide dismutase
    • Barkats, M.; Nakao, N.; Grasbon-Frodl, E. M.; Bilang-Bleuel, A.; Revah, F.; Mallet, J.; Brundin, P. Intrastriatal grafts of embryonic mesencephalic rat neurons genetically modified using an adenovirus encoding human Cu/Zn superoxide dismutase. Neuroscience 78:703-713; 1997.
    • (1997) Neuroscience , vol.78 , pp. 703-713
    • Barkats, M.1    Nakao, N.2    Grasbon-Frodl, E.M.3    Bilang-Bleuel, A.4    Revah, F.5    Mallet, J.6    Brundin, P.7
  • 8
    • 0030248550 scopus 로고    scopus 로고
    • The time course of loss of dopaminergic neurons and the gliotic reaction surrounding grafts of embryonic mesencephalon to the striatum
    • Barker, R. A.; Dunnett, S. B.; Faissner, A.; Fawcett, J. W. The time course of loss of dopaminergic neurons and the gliotic reaction surrounding grafts of embryonic mesencephalon to the striatum. Exp. Neurol. 141:79-93; 1996.
    • (1996) Exp. Neurol. , vol.141 , pp. 79-93
    • Barker, R.A.1    Dunnett, S.B.2    Faissner, A.3    Fawcett, J.W.4
  • 9
    • 0028929381 scopus 로고
    • A comparative study of preparation techniques for improving the viability of nigral grafts using vital stains, in vitro cultures, and in vivo grafts
    • Barker, R. A.; Fricker, R. A.; Abrous, D. N.; Fawcett, J.; Dunnett, S. B. A comparative study of preparation techniques for improving the viability of nigral grafts using vital stains, in vitro cultures, and in vivo grafts. Cell Transplant. 4:173-200; 1995.
    • (1995) Cell Transplant , vol.4 , pp. 173-200
    • Barker, R.A.1    Fricker, R.A.2    Abrous, D.N.3    Fawcett, J.4    Dunnett, S.B.5
  • 10
    • 0025933899 scopus 로고
    • Dopamine content and metabolism in mesencephalic and diencephalic cell cultures: Sex differences and effects of sex steroids
    • Beyer, C.; Pilgrim, C.; Reisert, I. Dopamine content and metabolism in mesencephalic and diencephalic cell cultures: Sex differences and effects of sex steroids. J. Neurosci. 11:1325-1333; 1991.
    • (1991) J. Neurosci. , vol.11 , pp. 1325-1333
    • Beyer, C.1    Pilgrim, C.2    Reisert, I.3
  • 11
    • 0002196763 scopus 로고
    • Dopamine-containing systems in the CNS
    • Björklund, A.; Hökfelt, T.; Kuhr, M. J., eds. Amsterdam: Elsevier Science Publishers
    • Björklund, A.; Lindvall, O. Dopamine-containing systems in the CNS. In: Björklund, A.; Hökfelt, T.; Kuhr, M. J., eds. Handbook of chemical neuroanatomy, vol. 2. Amsterdam: Elsevier Science Publishers; 1984:55-122.
    • (1984) Handbook of Chemical Neuroanatomy , vol.2 , pp. 55-122
    • Björklund, A.1    Lindvall, O.2
  • 12
    • 0021021418 scopus 로고
    • Intracerebral grafting of neuronal cell suspensions. I. Introduction and general methods of preparation
    • Björklund, A.; Stenevi, U.; Schmidt, R. H.; Dunnett, S. B.; Gage, F. H. Intracerebral grafting of neuronal cell suspensions. I. Introduction and general methods of preparation. Acta Physiol. Scand. 522:1-7; 1983.
    • (1983) Acta Physiol. Scand. , vol.522 , pp. 1-7
    • Björklund, A.1    Stenevi, U.2    Schmidt, R.H.3    Dunnett, S.B.4    Gage, F.H.5
  • 13
    • 0031266085 scopus 로고    scopus 로고
    • Tirilazad mesylate increases dopaminergic neuronal survival in the in Oculo grafting model
    • Björklund, L.; Spenger, C.; Strömberg, I. Tirilazad mesylate increases dopaminergic neuronal survival in the in Oculo grafting model. Exp. Neurol. 148:324-333; 1997.
    • (1997) Exp. Neurol. , vol.148 , pp. 324-333
    • Björklund, L.1    Spenger, C.2    Strömberg, I.3
  • 14
    • 0024518123 scopus 로고
    • The 21-aminosteroids: Potent inhibitors of lipid peroxidation for the treatment of central nervous system trauma and ischemia
    • Braughler, J. M.; Hall, E. D.; Jacobsen, E. J.; McCall, J. M.; Means, E. D. The 21-aminosteroids: Potent inhibitors of lipid peroxidation for the treatment of central nervous system trauma and ischemia. Drugs Future 14:143-152; 1989.
    • (1989) Drugs Future , vol.14 , pp. 143-152
    • Braughler, J.M.1    Hall, E.D.2    Jacobsen, E.J.3    McCall, J.M.4    Means, E.D.5
  • 15
    • 0029614765 scopus 로고
    • Neural apoptosis
    • Bredesen, D. E. Neural apoptosis. Ann. Neurol. 38:839-851; 1995.
    • (1995) Ann. Neurol. , vol.38 , pp. 839-851
    • Bredesen, D.E.1
  • 16
    • 0023073798 scopus 로고
    • Survival, growth and function of dopaminergic neurons grafted to the brain
    • Brundin, P.; Björklund, A. Survival, growth and function of dopaminergic neurons grafted to the brain. Prog. Brain Res. 71:293-308; 1987.
    • (1987) Prog. Brain Res. , vol.71 , pp. 293-308
    • Brundin, P.1    Björklund, A.2
  • 17
    • 0025170905 scopus 로고
    • Practical aspects of the use of human fetal brain tissue for intracerebral grafting
    • Brundin, P.; Björklund, A.; Lindvall, O. Practical aspects of the use of human fetal brain tissue for intracerebral grafting. Prog. Brain Res. 82:707-714; 1990.
    • (1990) Prog. Brain Res. , vol.82 , pp. 707-714
    • Brundin, P.1    Björklund, A.2    Lindvall, O.3
  • 18
    • 0003057732 scopus 로고
    • Functional effects of mesencephalic dopamine neurons and adrenal chromaffin cells grafted to the rodent striatum
    • Dunnett, S. B.; Björklund, A., eds. New York: Raven Press
    • Brundin, P.; Duan, W.-M.; Sauer, H. Functional effects of mesencephalic dopamine neurons and adrenal chromaffin cells grafted to the rodent striatum. In: Dunnett, S. B.; Björklund, A., eds. Functional neural transplantation. New York: Raven Press; 1994:9-46.
    • (1994) Functional Neural Transplantation , pp. 9-46
    • Brundin, P.1    Duan, W.-M.2    Sauer, H.3
  • 19
    • 0021954503 scopus 로고
    • Monitoring of cell viability in suspensions of embryonic CNS tissue and its use as a criterion for intracerebral graft survival
    • Brundin, P.; Isacson, O.; Björklund, A. Monitoring of cell viability in suspensions of embryonic CNS tissue and its use as a criterion for intracerebral graft survival. Brain Res. 331:251-259; 1985.
    • (1985) Brain Res. , vol.331 , pp. 251-259
    • Brundin, P.1    Isacson, O.2    Björklund, A.3
  • 20
    • 0022648056 scopus 로고
    • Intrastriatal grafting of dopamine-containing neuronal cell suspensions: Effects of mixing with target or non-target cells
    • Brundin, P.; Isacson, O.; Gage, F. H.; Björklund, A. Intrastriatal grafting of dopamine-containing neuronal cell suspensions: Effects of mixing with target or non-target cells. Dev. Brain Res. 24:77-84; 1986.
    • (1986) Dev. Brain Res. , vol.24 , pp. 77-84
    • Brundin, P.1    Isacson, O.2    Gage, F.H.3    Björklund, A.4
  • 22
    • 85013511339 scopus 로고
    • Preparation and intracerebral grafting of dissociated fetal brain tissue in rats
    • Conn, P. M., ed. New York: Academic Press
    • Brundin, P.; Strecker, R. E. Preparation and intracerebral grafting of dissociated fetal brain tissue in rats. In: Conn, P. M., ed. Methods in neurosciences, vol. 7 - lesions and transplantation. New York: Academic Press; 1991:305-326.
    • (1991) Methods in Neurosciences, Vol. 7 - Lesions and Transplantation , vol.7 , pp. 305-326
    • Brundin, P.1    Strecker, R.E.2
  • 23
    • 0023946501 scopus 로고
    • Human fetal dopamine neurons grafted in a rat model of Parkinson's disease: Immunological aspects, spontaneous and drug-induced behaviour, and dopamine release
    • Brundin, P.; Strecker, R. E.; Widner, H.; Clarke, D. J.; Nilsson, O. G.; Åstedt, B.; Lindvall, O.; Björklund, A. Human fetal dopamine neurons grafted in a rat model of Parkinson's disease: Immunological aspects, spontaneous and drug-induced behaviour, and dopamine release. Exp. Brain. Res. 70:192-208; 1988.
    • (1988) Exp. Brain. Res. , vol.70 , pp. 192-208
    • Brundin, P.1    Strecker, R.E.2    Widner, H.3    Clarke, D.J.4    Nilsson, O.G.5    Åstedt, B.6    Lindvall, O.7    Björklund, A.8
  • 24
    • 0031783647 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic growth factor inhibits apoptotic death of postnatal substantia nigra dopamine neurons in primary culture
    • Burke, R. E.; Antonelli, M.; Sulzer, D. Glial cell line-derived neurotrophic growth factor inhibits apoptotic death of postnatal substantia nigra dopamine neurons in primary culture. J. Neurochem. 71:517-525; 1998.
    • (1998) J. Neurochem. , vol.71 , pp. 517-525
    • Burke, R.E.1    Antonelli, M.2    Sulzer, D.3
  • 26
    • 0028181531 scopus 로고
    • α-phenyl-tert-butyl-nitrone reduces cortical infarct and edema in rats subjected to focal ischemia
    • Cao, X.; Phillis, J. W. α-phenyl-tert-butyl-nitrone reduces cortical infarct and edema in rats subjected to focal ischemia. Brain Res. 644:267-272; 1994.
    • (1994) Brain Res. , vol.644 , pp. 267-272
    • Cao, X.1    Phillis, J.W.2
  • 27
    • 0032535275 scopus 로고    scopus 로고
    • Mitochondrial control of acute glutamate excitotoxicity in cultured cerebellar granule cells
    • Castilho, R. F.; Hansson, O.; Ward, M. W.; Budd, S. L.; Nicholls, D. G. Mitochondrial control of acute glutamate excitotoxicity in cultured cerebellar granule cells. J. Neurosci. 18:10277-10286; 1998.
    • (1998) J. Neurosci. , vol.18 , pp. 10277-10286
    • Castilho, R.F.1    Hansson, O.2    Ward, M.W.3    Budd, S.L.4    Nicholls, D.G.5
  • 28
    • 0029888311 scopus 로고    scopus 로고
    • Role of oxidants in ischemic brain damage
    • Chan, P. K. Role of oxidants in ischemic brain damage. Stroke 27:1124-1129; 1996.
    • (1996) Stroke , vol.27 , pp. 1124-1129
    • Chan, P.K.1
  • 29
    • 0029552813 scopus 로고
    • GDNF reduces apoptosis in dopaminergic neurons in vitro
    • Clarkson, E. D.; Zawada, W. M.; Freed, C. R. GDNF reduces apoptosis in dopaminergic neurons in vitro. Neuroreport 7:145-149; 1995.
    • (1995) Neuroreport , vol.7 , pp. 145-149
    • Clarkson, E.D.1    Zawada, W.M.2    Freed, C.R.3
  • 30
    • 0023642584 scopus 로고
    • Production of superoxide anions by a CNS macrophage, the microglia
    • Colton, C. A.; Gilbert, D. L. Production of superoxide anions by a CNS macrophage, the microglia. FEBS Lett. 223:284-288; 1987.
    • (1987) FEBS Lett. , vol.223 , pp. 284-288
    • Colton, C.A.1    Gilbert, D.L.2
  • 31
    • 0028169805 scopus 로고
    • Enhanced efficacy of nigral-striatal cotransplants in bilaterally dopamine-depleted rats
    • Costantini, L. C.; Vozza, B. M.; Snyder-Keller, A. M. Enhanced efficacy of nigral-striatal cotransplants in bilaterally dopamine-depleted rats. Exp. Neurol. 127:219-231; 1994.
    • (1994) Exp. Neurol. , vol.127 , pp. 219-231
    • Costantini, L.C.1    Vozza, B.M.2    Snyder-Keller, A.M.3
  • 32
    • 0027686249 scopus 로고
    • Oxidative stress, glutamate, and neurodegenerative disorders
    • Coyle, J. T.; Puttfarcken, P. Oxidative stress, glutamate, and neurodegenerative disorders. Science 262:689-695; 1993
    • (1993) Science , vol.262 , pp. 689-695
    • Coyle, J.T.1    Puttfarcken, P.2
  • 33
    • 0031573475 scopus 로고    scopus 로고
    • Manganic porphyrins possess catalase activity and protect endothelial cells against hydrogen peroxide-mediated injury. Arch
    • Day, B. J.; Fridovich, I.; Crapo, J. D. Manganic porphyrins possess catalase activity and protect endothelial cells against hydrogen peroxide-mediated injury. Arch. Biochem. Biophys. 347:256-262; 1997.
    • (1997) Biochem. Biophys. , vol.347 , pp. 256-262
    • Day, B.J.1    Fridovich, I.2    Crapo, J.D.3
  • 34
    • 0030481801 scopus 로고    scopus 로고
    • Acute application of an interleukin-1 beta-converting enzyme-specific inhibitor delays axotomy-induced motoneurone death
    • de Bilbao, F.; Dubois-Dauphin, M. Acute application of an interleukin-1 beta-converting enzyme-specific inhibitor delays axotomy-induced motoneurone death. Neuroreport 25:3051-3054; 1996.
    • (1996) Neuroreport , vol.25 , pp. 3051-3054
    • De Bilbao, F.1    Dubois-Dauphin, M.2
  • 35
    • 0027302350 scopus 로고
    • Neurotrophic factor deprivation-induced death
    • Deckwerth, T. L.; Johnson, E. M., Jr. Neurotrophic factor deprivation-induced death. Ann. NY Acad. Sci. 679: 121-131; 1993.
    • (1993) Ann. NY Acad. Sci. , vol.679 , pp. 121-131
    • Deckwerth, T.L.1    Johnson E.M., Jr.2
  • 36
    • 0032192529 scopus 로고    scopus 로고
    • Evidence of a novel event during neuronal death: Development of competence-to-die in response to cytoplasmic cytochrome c
    • Deshmukh, M.; Johnson, E. M., Jr. Evidence of a novel event during neuronal death: Development of competence-to-die in response to cytoplasmic cytochrome c. Neuron 21:695-705; 1998.
    • (1998) Neuron , vol.21 , pp. 695-705
    • Deshmukh, M.1    Johnson E.M., Jr.2
  • 37
    • 0029047361 scopus 로고
    • Temporal pattern of host responses against intrastriatal grafts of syngeneic, allogeneic or xenogeneic embryonic neuronal tissue in rats
    • Duan, W.-M.; Widner, H.; Brundin, P. Temporal pattern of host responses against intrastriatal grafts of syngeneic, allogeneic or xenogeneic embryonic neuronal tissue in rats. Exp. Brain. Res. 104:227-242; 1995.
    • (1995) Exp. Brain. Res. , vol.104 , pp. 227-242
    • Duan, W.-M.1    Widner, H.2    Brundin, P.3
  • 38
    • 0028343507 scopus 로고
    • Neonatal motorneurons overexpressing the bcl-2 protooncogene in transgenic mice are protected from axotomy-induced cell death
    • USA
    • Dubois-Dauphin, M.; Frankowski, H.; Tsujimoto, Y.; Huarte, J.; Martinou, J.-C. Neonatal motorneurons overexpressing the bcl-2 protooncogene in transgenic mice are protected from axotomy-induced cell death. Proc. Natl. Acad. Sci. USA 91:3309-3313; 1994.
    • (1994) Proc. Natl. Acad. Sci. , vol.91 , pp. 3309-3313
    • Dubois-Dauphin, M.1    Frankowski, H.2    Tsujimoto, Y.3    Huarte, J.4    Martinou, J.-C.5
  • 39
    • 0028176098 scopus 로고
    • The ability of diphenylpiperazines to prevent neuronal death in dorsal root ganglion neurons in vitro after nerve growth factor deprivation and in vivo after axotomy
    • Eichler, M. E.; Dubinsky, J. M.; Tong, J.; Rich, K. M. The ability of diphenylpiperazines to prevent neuronal death in dorsal root ganglion neurons in vitro after nerve growth factor deprivation and in vivo after axotomy. J. Neurochem. 62:2148-2157; 1994.
    • (1994) J. Neurochem. , vol.62 , pp. 2148-2157
    • Eichler, M.E.1    Dubinsky, J.M.2    Tong, J.3    Rich, K.M.4
  • 40
    • 0032077862 scopus 로고    scopus 로고
    • Dose-related inversion of cinnarizine and flunarizine effects on mitochondrial permeability transition
    • Elimadi, A.; Bouillot, L.; Sapena, R.; Tillement, J. P.; Morin, D. Dose-related inversion of cinnarizine and flunarizine effects on mitochondrial permeability transition. Eur. J. Pharmacol. 348:115-121; 1998.
    • (1998) Eur. J. Pharmacol. , vol.348 , pp. 115-121
    • Elimadi, A.1    Bouillot, L.2    Sapena, R.3    Tillement, J.P.4    Morin, D.5
  • 41
    • 1642544935 scopus 로고    scopus 로고
    • Catalase and Mn(III) tetrakis (4-benzoic acid) porphyrin decrease death of grafted dopaminergic neurons
    • Emgård, M.; Castilho, R. F.; Brundin, P. Catalase and Mn(III) tetrakis (4-benzoic acid) porphyrin decrease death of grafted dopaminergic neurons. Soc. Neurosci. Abstr. 25:294.9; 1999.
    • (1999) Soc. Neurosci. Abstr. , vol.25 , pp. 2949
    • Emgård, M.1    Castilho, R.F.2    Brundin, P.3
  • 42
    • 0345102465 scopus 로고    scopus 로고
    • Patterns of cell death and dopaminergic neuron survival in intrastriatal nigral grafts
    • Emgård, M.; Karlsson, J.; Hansson, O.; Brundin, P. Patterns of cell death and dopaminergic neuron survival in intrastriatal nigral grafts. Exp. Neurol. 160:279-288; 1999.
    • (1999) Exp. Neurol. , vol.160 , pp. 279-288
    • Emgård, M.1    Karlsson, J.2    Hansson, O.3    Brundin, P.4
  • 43
    • 0030977069 scopus 로고    scopus 로고
    • Addition of lateral ganglionic eminence to rat mesencephalic grafts affects fiber outgrowth but does not enhance function
    • Emgård-Mattson, M.; Karlsson, J.; Nakao, N.; Brundin, P. Addition of lateral ganglionic eminence to rat mesencephalic grafts affects fiber outgrowth but does not enhance function. Cell Transplant. 6:277-286; 1997.
    • (1997) Cell Transplant , vol.6 , pp. 277-286
    • Emgård-Mattson, M.1    Karlsson, J.2    Nakao, N.3    Brundin, P.4
  • 44
    • 0025006032 scopus 로고
    • Microtransplantation of neural cells into adult rat brain
    • Emmett, C. J.; Jaques-Berg, W.; Seeley, P. J. Microtransplantation of neural cells into adult rat brain. Neuroscience 38:213-222; 1990.
    • (1990) Neuroscience , vol.38 , pp. 213-222
    • Emmett, C.J.1    Jaques-Berg, W.2    Seeley, P.J.3
  • 45
    • 0031904403 scopus 로고    scopus 로고
    • Spatial and temporal growth factor influences on developing midbrain dopaminergic neurons
    • Engele, J. Spatial and temporal growth factor influences on developing midbrain dopaminergic neurons. J. Neurosci. Res. 53:405-414; 1998.
    • (1998) J. Neurosci. Res. , vol.53 , pp. 405-414
    • Engele, J.1
  • 46
    • 0026042368 scopus 로고
    • The neurotrophic effects of fibroblast growth factors on dopaminergic neurons in vitro are mediated by mesencephalic glia
    • Engele, J.; Bohn, M. C. The neurotrophic effects of fibroblast growth factors on dopaminergic neurons in vitro are mediated by mesencephalic glia. J. Neurosci. 11: 3070-3078; 1991.
    • (1991) J. Neurosci. , vol.11 , pp. 3070-3078
    • Engele, J.1    Bohn, M.C.2
  • 47
    • 0029047946 scopus 로고
    • bcl-2 transgene expression can protect neurons against developmental and induced cell death
    • USA
    • Farlie, P. G.; Dringen, R.; Rees, S. M.; Kannourakis, G.; Bernard, O. bcl-2 transgene expression can protect neurons against developmental and induced cell death. Proc. Natl. Acad. Sci. USA 92:4397-4401; 1995.
    • (1995) Proc. Natl. Acad. Sci. , vol.92 , pp. 4397-4401
    • Farlie, P.G.1    Dringen, R.2    Rees, S.M.3    Kannourakis, G.4    Bernard, O.5
  • 48
    • 0027989826 scopus 로고
    • Stable Mn(III) porphyrins mimic superoxide dismutase in vitro and substitute for it in vivo
    • Faulkner, K. M.; Liochev, S. I.; Fridovich, I. Stable Mn(III) porphyrins mimic superoxide dismutase in vitro and substitute for it in vivo. J. Biol. Chem. 269:23471-23476; 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 23471-23476
    • Faulkner, K.M.1    Liochev, S.I.2    Fridovich, I.3
  • 49
    • 0028850558 scopus 로고
    • Dopaminergic neuronal survival and the effects of bFGF in explant, three dimensional and monolayer cultures of embryonic rat ventral mesencephalon
    • Fawcett, J. W.; Barker, R. A.; Dunnett, S. B. Dopaminergic neuronal survival and the effects of bFGF in explant, three dimensional and monolayer cultures of embryonic rat ventral mesencephalon. Exp. Brain Res. 106:275-282; 1995.
    • (1995) Exp. Brain Res. , vol.106 , pp. 275-282
    • Fawcett, J.W.1    Barker, R.A.2    Dunnett, S.B.3
  • 50
    • 0024521368 scopus 로고
    • Basic fibroblast growth factor promotes the survival and development of mesencephalic neurons in culture
    • Ferrari, G.; Minozzi, M. C.; Toffano, G.; Leon, A.; Skaper, S. D. Basic fibroblast growth factor promotes the survival and development of mesencephalic neurons in culture. Dev. Biol. 133:140-147; 1989.
    • (1989) Dev. Biol. , vol.133 , pp. 140-147
    • Ferrari, G.1    Minozzi, M.C.2    Toffano, G.3    Leon, A.4    Skaper, S.D.5
  • 51
    • 0029909709 scopus 로고    scopus 로고
    • Effects of lazaroids and a peroxynitrite scavenger in a cell model of peroxynitrite toxicity
    • Fici, G. J.; Althaus, J. S.; VonVoigtlander, P. F. Effects of lazaroids and a peroxynitrite scavenger in a cell model of peroxynitrite toxicity. Free Radic. Biol. Med. 22:223-228; 1997.
    • (1997) Free Radic. Biol. Med. , vol.22 , pp. 223-228
    • Fici, G.J.1    Althaus, J.S.2    Vonvoigtlander, P.F.3
  • 52
    • 0024542379 scopus 로고
    • Nimodipine enhances growth factor vascularization of neural grafts
    • Finger, S.; Dunnett, S. B. Nimodipine enhances growth factor vascularization of neural grafts. Exp. Neurol. 104: 1-9; 1989.
    • (1989) Exp. Neurol. , vol.104 , pp. 1-9
    • Finger, S.1    Dunnett, S.B.2
  • 53
    • 0026647763 scopus 로고
    • Free radical damage to protein and DNA: Mechanisms involved and relevant observations on brain undergoing oxidative stress
    • Floyd, R. A.; Carney, J. M. Free radical damage to protein and DNA: Mechanisms involved and relevant observations on brain undergoing oxidative stress. Ann. Neurol. 32:S22-S27; 1992.
    • (1992) Ann. Neurol. , vol.32
    • Floyd, R.A.1    Carney, J.M.2
  • 54
    • 0028229549 scopus 로고
    • Human embryonic dopamine neurons xenografted to the rat: Effects of cryopreservation and varying regional source of donor cells on transplant survival, morphology and function
    • Frodl, E. M.; Duan, W. M.; Sauer, H.; Kupsch, A.; Brundin, P. Human embryonic dopamine neurons xenografted to the rat: Effects of cryopreservation and varying regional source of donor cells on transplant survival, morphology and function. Brain Res. 647:286-298; 1994.
    • (1994) Brain Res. , vol.647 , pp. 286-298
    • Frodl, E.M.1    Duan, W.M.2    Sauer, H.3    Kupsch, A.4    Brundin, P.5
  • 55
    • 0028073457 scopus 로고
    • Lazaroids improve the survival of cultured rat embryonic mesencephalic neurones
    • Frodl, E. M.; Nakao, N.; Brundin, P. Lazaroids improve the survival of cultured rat embryonic mesencephalic neurones. Neuroreport 5:2393-2396; 1994.
    • (1994) Neuroreport , vol.5 , pp. 2393-2396
    • Frodl, E.M.1    Nakao, N.2    Brundin, P.3
  • 56
    • 0021057103 scopus 로고
    • Three-dimensional computer reconstruction of midbrain dopaminergic neuronal populations: From mouse to man
    • German, D. C.; Schlusselberg, D. S.; Woodward, D. J. Three-dimensional computer reconstruction of midbrain dopaminergic neuronal populations: From mouse to man. J. Neural. Transm. 57:243-254; 1983.
    • (1983) J. Neural. Transm. , vol.57 , pp. 243-254
    • German, D.C.1    Schlusselberg, D.S.2    Woodward, D.J.3
  • 57
    • 0031887788 scopus 로고    scopus 로고
    • Inflammation in traumatic brain injury: Role of cytokines and chemokines
    • Ghirnikar, R. S.; Lee, Y. L.; Eng, L. F. Inflammation in traumatic brain injury: Role of cytokines and chemokines. Neurochem. Res. 23:329-340; 1998.
    • (1998) Neurochem. Res. , vol.23 , pp. 329-340
    • Ghirnikar, R.S.1    Lee, Y.L.2    Eng, L.F.3
  • 58
    • 0031022729 scopus 로고    scopus 로고
    • Lipid peroxides are generated by the fetal rat brain after episodes of global ischemia in utero
    • Glozman, S.; Yavin, E. Lipid peroxides are generated by the fetal rat brain after episodes of global ischemia in utero. Neurochem. Res. 22:201-208; 1997.
    • (1997) Neurochem. Res. , vol.22 , pp. 201-208
    • Glozman, S.1    Yavin, E.2
  • 60
    • 0029817315 scopus 로고    scopus 로고
    • Lazaroid treatment prevents death of cultured rat embryonic mesencephalic neurons following glutathione depletion
    • Grasbon-Frodl, E. M.; Andersson, A.; Brundin, P. Lazaroid treatment prevents death of cultured rat embryonic mesencephalic neurons following glutathione depletion. J. Neurochem. 67:1653-1660; 1996.
    • (1996) J. Neurochem. , vol.67 , pp. 1653-1660
    • Grasbon-Frodl, E.M.1    Andersson, A.2    Brundin, P.3
  • 61
    • 0031026026 scopus 로고    scopus 로고
    • Mesencephalic neuron death induced by congeners of nitrogen monoxide is prevented by the lazaroid U-83836E
    • Grasbon-Frodl, E. M.; Brundin, P. Mesencephalic neuron death induced by congeners of nitrogen monoxide is prevented by the lazaroid U-83836E. Exp. Brain Res. 113: 138-143; 1997.
    • (1997) Exp. Brain Res. , vol.113 , pp. 138-143
    • Grasbon-Frodl, E.M.1    Brundin, P.2
  • 62
    • 0029920694 scopus 로고    scopus 로고
    • The lazaroid U-83836E improves the survival of rat embryonic mesencephalic tissue stored at 4 degrees C and subsequently used for cultures or intracerebral transplantation
    • Grasbon-Frodl, E. M.; Nakao, N.; Brundin, P. The lazaroid U-83836E improves the survival of rat embryonic mesencephalic tissue stored at 4 degrees C and subsequently used for cultures or intracerebral transplantation. Brain Res. Bull. 39:341-347; 1996.
    • (1996) Brain Res. Bull. , vol.39 , pp. 341-347
    • Grasbon-Frodl, E.M.1    Nakao, N.2    Brundin, P.3
  • 63
    • 0032544268 scopus 로고    scopus 로고
    • Apoptotic pathways: The roads to ruin
    • Green, D. R. Apoptotic pathways: The roads to ruin. Cell 94:695-698; 1998.
    • (1998) Cell , vol.94 , pp. 695-698
    • Green, D.R.1
  • 65
    • 0002437731 scopus 로고    scopus 로고
    • Lipid antioxidant neuroprotectants for acute and chronic neurodegenerative disorders
    • Bär, P. R.; Beal, M. F., eds. New York: Marcel Dekker Inc.
    • Hall, E. D. Lipid antioxidant neuroprotectants for acute and chronic neurodegenerative disorders. In: Bär, P. R.; Beal, M. F., eds. Neuroprotection in CNS diseases. New York: Marcel Dekker Inc.; 1997:161-181.
    • (1997) Neuroprotection in CNS Diseases , pp. 161-181
    • Hall, E.D.1
  • 66
    • 0026754574 scopus 로고
    • Reactive oxygen species and the central nervous system
    • Halliwell, B. Reactive oxygen species and the central nervous system. J. Neurochem. 59:1609-1623; 1992.
    • (1992) J. Neurochem. , vol.59 , pp. 1609-1623
    • Halliwell, B.1
  • 67
    • 0028864546 scopus 로고
    • In vivo effects of kFGF on embryonic nigral grafts in a rat model of Parkinson's disease
    • Haque, N. S.; Hlavin, M. L.; Du, J. S.; Fawcett, J. W.; Dunnett, S. B. In vivo effects of kFGF on embryonic nigral grafts in a rat model of Parkinson's disease. Neuroreport 6:2177-2181. 1995.
    • (1995) Neuroreport , vol.6 , pp. 2177-2181
    • Haque, N.S.1    Hlavin, M.L.2    Du, J.S.3    Fawcett, J.W.4    Dunnett, S.B.5
  • 68
    • 0029962204 scopus 로고    scopus 로고
    • The neurotrophin NT4/5, but not NT3, enhances the efficacy of nigral grafts in a rat model of Parkinson's disease
    • Haque, N. S.; Hlavin, M. L.; Fawcett, J. W.; Dunnett, S. B. The neurotrophin NT4/5, but not NT3, enhances the efficacy of nigral grafts in a rat model of Parkinson's disease. Brain Res. 712:45-52; 1996.
    • (1996) Brain Res. , vol.712 , pp. 45-52
    • Haque, N.S.1    Hlavin, M.L.2    Fawcett, J.W.3    Dunnett, S.B.4
  • 70
    • 0015526288 scopus 로고
    • Neuronal degeneration in rat brain induced by 6-hydroxydopamine: A histological and biochemical study
    • Hedreen, J. C.; Chalmers, J. P. Neuronal degeneration in rat brain induced by 6-hydroxydopamine: A histological and biochemical study. Brain Res. 47:1-30; 1972.
    • (1972) Brain Res. , vol.47 , pp. 1-30
    • Hedreen, J.C.1    Chalmers, J.P.2
  • 71
    • 0025978546 scopus 로고
    • Intracellular calcium-binding proteins: More sites than insights. Trends
    • Heizmann, C. W.; Hunziker, W. Intracellular calcium-binding proteins: More sites than insights. Trends Biochem. Sci. 16:98-103; 1991.
    • (1991) Biochem. Sci. , vol.16 , pp. 98-103
    • Heizmann, C.W.1    Hunziker, W.2
  • 73
    • 0025876757 scopus 로고
    • BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra
    • Hyman, C.; Hofer, M.; Barde, Y. A.; Juhasz, M.; Yancopoulos, G. D.; Lindsay, R. M. BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra. Nature 350:230-232; 1991.
    • (1991) Nature , vol.350 , pp. 230-232
    • Hyman, C.1    Hofer, M.2    Barde, Y.A.3    Juhasz, M.4    Yancopoulos, G.D.5    Lindsay, R.M.6
  • 74
    • 0027972545 scopus 로고
    • Overlapping and distinct actions of the neurotrophins BDNF, NT-3, and NT-4/5 on cultured dopaminergic and GABAergic neurons of the ventral mesencephalon
    • Hyman, C.; Juhasz, M.; Jackson, C.; Wright, P.; Ip, N. Y.; Lindsay, R. M. Overlapping and distinct actions of the neurotrophins BDNF, NT-3, and NT-4/5 on cultured dopaminergic and GABAergic neurons of the ventral mesencephalon. J. Neurosci. 14:335-347; 1994.
    • (1994) J. Neurosci. , vol.14 , pp. 335-347
    • Hyman, C.1    Juhasz, M.2    Jackson, C.3    Wright, P.4    Ip, N.Y.5    Lindsay, R.M.6
  • 75
    • 0027407590 scopus 로고
    • Naturally occurring cell death during postnatal development in the substantia nigra pars compacta of rat
    • Janec, E.; Burke, R. E. Naturally occurring cell death during postnatal development in the substantia nigra pars compacta of rat. Mol. Cell. Neurosci. 4:30-35; 1993.
    • (1993) Mol. Cell. Neurosci. , vol.4 , pp. 30-35
    • Janec, E.1    Burke, R.E.2
  • 76
    • 0029751104 scopus 로고    scopus 로고
    • Oxidative stress and the pathogenesis of Parkinson's disease
    • Jenner, P.; Olanow, C. W. Oxidative stress and the pathogenesis of Parkinson's disease. Neurology 47: S161-170; 1996.
    • (1996) Neurology , vol.47
    • Jenner, P.1    Olanow, C.W.2
  • 77
    • 0013670016 scopus 로고    scopus 로고
    • Flunarizine improves the survival of grafted dopaminergic neurons
    • Kaminski Schierle, G. S.; Hansson, O.; Brundin, P. Flunarizine improves the survival of grafted dopaminergic neurons. Neuroscience 94:17-20; 1999.
    • (1999) Neuroscience , vol.94 , pp. 17-20
    • Kaminski Schierle, G.S.1    Hansson, O.2    Brundin, P.3
  • 78
    • 0344938398 scopus 로고    scopus 로고
    • Treatment with the spin-trap agent α-phenyl-tert-butyl nitrone does not enhance the survival of embryonic or adult dopamine neurons
    • Karlsson, J.; Emgård, M.; Rosenblad, C.; Brundin, P. Treatment with the spin-trap agent α-phenyl-tert-butyl nitrone does not enhance the survival of embryonic or adult dopamine neurons. Brain Res. 805:155-168; 1998.
    • (1998) Brain Res. , vol.805 , pp. 155-168
    • Karlsson, J.1    Emgård, M.2    Rosenblad, C.3    Brundin, P.4
  • 79
    • 0342365775 scopus 로고    scopus 로고
    • Effects of euthanasia and lazaroids on survival of grafted dopaminergic neurones
    • in press
    • Karlsson, J.; Love, R.; Clarke, D. J.; Brundin, P. Effects of euthanasia and lazaroids on survival of grafted dopaminergic neurones. Brain Res. Interact. (in press).
    • Brain Res. Interact.
    • Karlsson, J.1    Love, R.2    Clarke, D.J.3    Brundin, P.4
  • 80
    • 0031840847 scopus 로고    scopus 로고
    • Cell-permeable scavengers of superoxide prevent long-term potentiation in hippocampal area CA1
    • Klann E. Cell-permeable scavengers of superoxide prevent long-term potentiation in hippocampal area CA1. J. Neurophysiol. 80:452-457; 1998.
    • (1998) J. Neurophysiol. , vol.80 , pp. 452-457
    • Klann, E.1
  • 84
    • 0031918742 scopus 로고    scopus 로고
    • The mitochondrial death/life regulator in apoptosis and necrosis
    • Kroemer, G.; Dallaporta, B.; Resche-Rigon, M. The mitochondrial death/life regulator in apoptosis and necrosis. Annu. Rev. Physiol. 60:619-642; 1998.
    • (1998) Annu. Rev. Physiol. , vol.60 , pp. 619-642
    • Kroemer, G.1    Dallaporta, B.2    Resche-Rigon, M.3
  • 85
    • 0031816414 scopus 로고    scopus 로고
    • Apoptosis, excitotoxicity, and neuropathology
    • Leist, M.; Nicotera, P. Apoptosis, excitotoxicity, and neuropathology. Exp. Cell Res. 239:183-201; 1998.
    • (1998) Exp. Cell Res. , vol.239 , pp. 183-201
    • Leist, M.1    Nicotera, P.2
  • 87
    • 0027285510 scopus 로고
    • GDNF: A glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons
    • Lin, L. F.; Doherty, D. H.; Lile, J. D.; Bektesh, S.; Collins, F. GDNF: A glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 260: 1130-1132; 1993.
    • (1993) Science , vol.260 , pp. 1130-1132
    • Lin, L.F.1    Doherty, D.H.2    Lile, J.D.3    Bektesh, S.4    Collins, F.5
  • 89
    • 0028004643 scopus 로고
    • Secondary mechanisms in neuronal trauma
    • Lynch, D. R.; Dawson, T. M. Secondary mechanisms in neuronal trauma. Curr. Opin. Neurol. 7:510-516; 1994.
    • (1994) Curr. Opin. Neurol. , vol.7 , pp. 510-516
    • Lynch, D.R.1    Dawson, T.M.2
  • 90
    • 0027944626 scopus 로고
    • Programmed cell death in developing grafts of fetal substantia nigra
    • Mahalik, T. J.; Hahn, W. E.; Clayton, G. H.; Owens, G. P. Programmed cell death in developing grafts of fetal substantia nigra. Exp. Neurol. 129:27-36; 1994.
    • (1994) Exp. Neurol. , vol.129 , pp. 27-36
    • Mahalik, T.J.1    Hahn, W.E.2    Clayton, G.H.3    Owens, G.P.4
  • 92
    • 0032007328 scopus 로고    scopus 로고
    • Modification of ion homeostasis by lipid peroxidation: Roles in neuronal degeneration and adaptive plasticity
    • Mattson, M. P. Modification of ion homeostasis by lipid peroxidation: Roles in neuronal degeneration and adaptive plasticity. Trends Neurosci. 21:53-57; 1998.
    • (1998) Trends Neurosci. , vol.21 , pp. 53-57
    • Mattson, M.P.1
  • 93
    • 0027236053 scopus 로고
    • Basic fibroblast growth factor promotes the survival of embryonic ventral mesencephalic dopaminergic neurons - II. Effects on nigral transplants in vivo
    • Mayer, E.; Dunnett, S. B.; Fawcett, J. W. Basic fibroblast growth factor promotes the survival of embryonic ventral mesencephalic dopaminergic neurons - II. Effects on nigral transplants in vivo. Neuroscience 56:389-398; 1993.
    • (1993) Neuroscience , vol.56 , pp. 389-398
    • Mayer, E.1    Dunnett, S.B.2    Fawcett, J.W.3
  • 94
    • 0031720458 scopus 로고    scopus 로고
    • Differential expression and association of calcium channel subunits in development and disease
    • McEnery, M. W.; Vance, C. L.; Begg, C. M.; Lee, W. L.; Choi, Y.; Dubel, S. J. Differential expression and association of calcium channel subunits in development and disease. J. Bioenerg. Biomembr. 30:409-418; 1998.
    • (1998) J. Bioenerg. Biomembr. , vol.30 , pp. 409-418
    • McEnery, M.W.1    Vance, C.L.2    Begg, C.M.3    Lee, W.L.4    Choi, Y.5    Dubel, S.J.6
  • 95
    • 0027377278 scopus 로고
    • Novel pharmacologic therapies in the treatment of experimental traumatic brain injury: A review
    • McIntosh, T. K. Novel pharmacologic therapies in the treatment of experimental traumatic brain injury: A review. J. Neurotrauma 10:215-261; 1993.
    • (1993) J. Neurotrauma , vol.10 , pp. 215-261
    • McIntosh, T.K.1
  • 96
    • 0031812748 scopus 로고    scopus 로고
    • Enhancement of graft survival and sensorimotor behavioral recovery in rats undergoing transplantation with dopaminergic cells exposed to glial cell line-derived neurotrophic factor
    • Mehta, V.; Hong, M.; Spears, J.; Mendez, I. Enhancement of graft survival and sensorimotor behavioral recovery in rats undergoing transplantation with dopaminergic cells exposed to glial cell line-derived neurotrophic factor. J. Neurosurg. 88:1088-1095; 1998.
    • (1998) J. Neurosurg. , vol.88 , pp. 1088-1095
    • Mehta, V.1    Hong, M.2    Spears, J.3    Mendez, I.4
  • 98
    • 0028574168 scopus 로고
    • Lazaroids improve the survival of grafted rat embryonic dopamine neurons
    • USA
    • Nakao, N.; Frodl, E. M.; Duan, W.-M.; Widner, H.; Brundin, P. Lazaroids improve the survival of grafted rat embryonic dopamine neurons. Proc. Natl. Acad. Sci. USA 91:12408-12412; 1994.
    • (1994) Proc. Natl. Acad. Sci. , vol.91 , pp. 12408-12412
    • Nakao, N.1    Frodl, E.M.2    Duan, W.-M.3    Widner, H.4    Brundin, P.5
  • 99
    • 0028899401 scopus 로고
    • Overexpressing Cu/Zn superoxide dismutase enhances survival of transplanted neurons in a rat model of Parkinson's disease
    • Nakao, N.; Frodl, E. M.; Widner, H.; Carlson, E.; Eggerding, F. A.; Epstein, C. J.; Brundin, P. Overexpressing Cu/Zn superoxide dismutase enhances survival of transplanted neurons in a rat model of Parkinson's disease. Nat. Med. 1:226-231; 1995.
    • (1995) Nat. Med. , vol.1 , pp. 226-231
    • Nakao, N.1    Frodl, E.M.2    Widner, H.3    Carlson, E.4    Eggerding, F.A.5    Epstein, C.J.6    Brundin, P.7
  • 100
    • 0029995487 scopus 로고    scopus 로고
    • Antioxidant treatment protects striatal neurons against excitotoxic insults
    • Nakao, N.; Grasbon-Frodl, E. M.; Widner, H.; Brundin, P. Antioxidant treatment protects striatal neurons against excitotoxic insults. Neuroscience 73:185-200; 1996.
    • (1996) Neuroscience , vol.73 , pp. 185-200
    • Nakao, N.1    Grasbon-Frodl, E.M.2    Widner, H.3    Brundin, P.4
  • 101
    • 0029153487 scopus 로고
    • Preservation of fetal ventral mesencephalic cells by cool storage: In-vitro viability and TH-positive neuron survival after microtransplantation to the striatum
    • Nikkhah, G.; Eberhard, J.; Olsson, M.; Björklund, A. Preservation of fetal ventral mesencephalic cells by cool storage: In-vitro viability and TH-positive neuron survival after microtransplantation to the striatum. Brain Res. 687:22-34; 1995.
    • (1995) Brain Res. , vol.687 , pp. 22-34
    • Nikkhah, G.1    Eberhard, J.2    Olsson, M.3    Björklund, A.4
  • 102
    • 0028138846 scopus 로고
    • A microtransplantation approach for cell suspension grafting in the rat Parkinson model: A detailed account of the methodology
    • Nikkhah, G.; Olsson, M.; Eberhard, J.; Bentlage, C.; Cunningham, M. G.; Björklund, A. A microtransplantation approach for cell suspension grafting in the rat Parkinson model: A detailed account of the methodology. Neuroscience 63:57-72; 1994.
    • (1994) Neuroscience , vol.63 , pp. 57-72
    • Nikkhah, G.1    Olsson, M.2    Eberhard, J.3    Bentlage, C.4    Cunningham, M.G.5    Björklund, A.6
  • 103
    • 0032510758 scopus 로고    scopus 로고
    • Transgenic mice expressing human Bcl-2 in their neurons are resistant to 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity
    • USA
    • Offen, D.; Beart, P. M.; Cheung, N. S.; Pascoe, C. J.; Hochman, A.; Gorodin, S.; Melamed, E.; Bernard, R.; Bernard, O. Transgenic mice expressing human Bcl-2 in their neurons are resistant to 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity. Proc. Natl. Acad. Sci. USA 95:5789-5794; 1998.
    • (1998) Proc. Natl. Acad. Sci. , vol.95 , pp. 5789-5794
    • Offen, D.1    Beart, P.M.2    Cheung, N.S.3    Pascoe, C.J.4    Hochman, A.5    Gorodin, S.6    Melamed, E.7    Bernard, R.8    Bernard, O.9
  • 104
    • 0026704066 scopus 로고
    • An introduction to the free radical hypothesis in Parkinson's disease
    • Olanow, C. W. An introduction to the free radical hypothesis in Parkinson's disease. Ann. Neurol. 32(Suppl.): S2-9; 1992.
    • (1992) Ann. Neurol. , vol.32 , Issue.SUPPL.
    • Olanow, C.W.1
  • 105
    • 0025309904 scopus 로고
    • Oxidative damage to brain proteins, loss of glutamine synthetase activity, and production of free radicals during ischemia/reperfusion-induced injury to gerbil brain
    • USA
    • Oliver, C. N.; Starke-Reed, P. E.; Stadtman, E. R.; Liu, G. J.; Carney, J. M.; Floyd, R. A. Oxidative damage to brain proteins, loss of glutamine synthetase activity, and production of free radicals during ischemia/reperfusion-induced injury to gerbil brain. Proc. Natl. Acad. Sci. USA 87:5144-5147; 1990.
    • (1990) Proc. Natl. Acad. Sci. , vol.87 , pp. 5144-5147
    • Oliver, C.N.1    Starke-Reed, P.E.2    Stadtman, E.R.3    Liu, G.J.4    Carney, J.M.5    Floyd, R.A.6
  • 106
    • 0001933595 scopus 로고
    • Neurotoxicity of excitatory amino acids
    • McGeer, E. G.; Olney, J. W.; McGeer, P. L., eds. New York: Raven Press
    • Olney, J. W. Neurotoxicity of excitatory amino acids. In: McGeer, E. G.; Olney, J. W.; McGeer, P. L., eds. Kainic acid as a tool in neurobiology. New York: Raven Press; 1978:95-121.
    • (1978) Kainic Acid As a Tool in Neurobiology , pp. 95-121
    • Olney, J.W.1
  • 107
    • 0026058318 scopus 로고
    • Cell death during development of the nervous system
    • Oppenheim, R. W. Cell death during development of the nervous system. Annu. Rev. Neurosci. 14:453-501; 1991.
    • (1991) Annu. Rev. Neurosci. , vol.14 , pp. 453-501
    • Oppenheim, R.W.1
  • 109
    • 0031257754 scopus 로고    scopus 로고
    • Tirilazad mesylate improves survival of rat and human embryonic mesencephalic neurons in vitro
    • Erratum published in Exp. Neurol. 154: 260; 1998
    • Othberg, A.; Keep, M.; Brundin, P.; Lindvall, O. Tirilazad mesylate improves survival of rat and human embryonic mesencephalic neurons in vitro. Exp. Neurol. 147: 498-502; 1997. [Erratum published in Exp. Neurol. 154: 260; 1998]
    • (1997) Exp. Neurol. , vol.147 , pp. 498-502
    • Othberg, A.1    Keep, M.2    Brundin, P.3    Lindvall, O.4
  • 110
    • 0032055973 scopus 로고    scopus 로고
    • Neuronal cell death
    • Pettmann, B.; Hendersen, C. E. Neuronal cell death. Neuron 20:633-647; 1998.
    • (1998) Neuron , vol.20 , pp. 633-647
    • Pettmann, B.1    Hendersen, C.E.2
  • 111
    • 0029037495 scopus 로고
    • The chemistry of peroxynitrite: A product from the reaction of nitric oxide with superoxide
    • Pryor, W. A.; Squadrito, G. L. The chemistry of peroxynitrite: A product from the reaction of nitric oxide with superoxide. Am. J. Physiol. 268:L699-L722; 1995.
    • (1995) Am. J. Physiol. , vol.268
    • Pryor, W.A.1    Squadrito, G.L.2
  • 112
    • 0027373764 scopus 로고
    • Programmed cell death and the control of cell survival: Lessons from the nervous system
    • Raff, M. C.; Barres, B. A.; Burne, J. F.; Coles, H. S.; Ishizaki, Y.; Jacobson, M. D. Programmed cell death and the control of cell survival: Lessons from the nervous system. Science 262:695-700; 1993.
    • (1993) Science , vol.262 , pp. 695-700
    • Raff, M.C.1    Barres, B.A.2    Burne, J.F.3    Coles, H.S.4    Ishizaki, Y.5    Jacobson, M.D.6
  • 114
    • 0030298512 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor increases survival, growth and function of intrastriatal fetal nigral dopaminergic grafts
    • Rosenblad, C.; Martinez-Serrano, A.; Björklund, A. Glial cell line-derived neurotrophic factor increases survival, growth and function of intrastriatal fetal nigral dopaminergic grafts. Neuroscience 75:979-985; 1996.
    • (1996) Neuroscience , vol.75 , pp. 979-985
    • Rosenblad, C.1    Martinez-Serrano, A.2    Björklund, A.3
  • 115
    • 0025846973 scopus 로고
    • Effects of cool storage on survival and function of intrastriatal ventral mesencephalic grafts
    • Sauer, H.; Brundin, P. Effects of cool storage on survival and function of intrastriatal ventral mesencephalic grafts. Restor. Neurol. Neurosci. 2:123-135; 1991.
    • (1991) Restor. Neurol. Neurosci. , vol.2 , pp. 123-135
    • Sauer, H.1    Brundin, P.2
  • 116
    • 0027497084 scopus 로고
    • Brain-derived neurotrophic factor enhances function rather than survival of intrastriatal dopamine cell-rich grafts
    • Sauer, H.; Fischer, W.; Nikkhah, G.; Wiegand, S. J.; Brundin, P.; Lindsay, R. M.; Björklund, A. Brain-derived neurotrophic factor enhances function rather than survival of intrastriatal dopamine cell-rich grafts. Brain Res. 626:37-44; 1993.
    • (1993) Brain Res. , vol.626 , pp. 37-44
    • Sauer, H.1    Fischer, W.2    Nikkhah, G.3    Wiegand, S.J.4    Brundin, P.5    Lindsay, R.M.6    Björklund, A.7
  • 117
    • 0031936437 scopus 로고    scopus 로고
    • Implants of polymer-encapsulated genetically modified cells releasing glial cell line-derived neurotrophic factor improve survival, growth, and function of fetal dopaminergic grafts
    • Sautter, J.; Tseng, J. L.; Braguglia, D.; Aebischer, P.; Spenger, C.; Seiler, R. W.; Widmer, H. R.; Zurn, A. D. Implants of polymer-encapsulated genetically modified cells releasing glial cell line-derived neurotrophic factor improve survival, growth, and function of fetal dopaminergic grafts. Exp. Neurol. 149:230-236; 1998.
    • (1998) Exp. Neurol. , vol.149 , pp. 230-236
    • Sautter, J.1    Tseng, J.L.2    Braguglia, D.3    Aebischer, P.4    Spenger, C.5    Seiler, R.W.6    Widmer, H.R.7    Zurn, A.D.8
  • 118
    • 0032975889 scopus 로고    scopus 로고
    • Excitotoxicity plays a role in the death of tyrosine hydroxylase-immunopositive nigral neurons cultured in serum-free medium
    • Schierle, G. S.; Brundin, P. Excitotoxicity plays a role in the death of tyrosine hydroxylase-immunopositive nigral neurons cultured in serum-free medium. Exp. Neurol. 157:338-348; 1999.
    • (1999) Exp. Neurol. , vol.157 , pp. 338-348
    • Schierle, G.S.1    Brundin, P.2
  • 119
    • 0033008216 scopus 로고    scopus 로고
    • Caspase inhibition reduces apoptosis and increases survival of nigral transplants
    • Schierle, G. S.; Hansson, O.; Leist, M.; Nicotera, P.; Widner, H.; Brundin, P. Caspase inhibition reduces apoptosis and increases survival of nigral transplants. Nat. Med. 5:97-100; 1999.
    • (1999) Nat. Med. , vol.5 , pp. 97-100
    • Schierle, G.S.1    Hansson, O.2    Leist, M.3    Nicotera, P.4    Widner, H.5    Brundin, P.6
  • 120
    • 0012061554 scopus 로고    scopus 로고
    • MK-801 treatment does not enhance the survival of grafted dopamine neurones
    • Schierle, G. S.; Karlsson, J.; Brundin, P. MK-801 treatment does not enhance the survival of grafted dopamine neurones. Neuroreport 9:1113-1116; 1998.
    • (1998) Neuroreport , vol.9 , pp. 1113-1116
    • Schierle, G.S.1    Karlsson, J.2    Brundin, P.3
  • 121
    • 0032880090 scopus 로고    scopus 로고
    • Differential effects of Bcl-2 overexpression on fibre outgrowth and survival of embryonic dopaminergic neurons in intracerebral transplants
    • Schierle, G. S.; Leist, M.; Martinou, J. C.; Widner, H.; Nicotera, P.; Brundin, P. Differential effects of Bcl-2 overexpression on fibre outgrowth and survival of embryonic dopaminergic neurons in intracerebral transplants. Eur. J. Neurosci. 11:3073-3081; 1999.
    • (1999) Eur. J. Neurosci. , vol.11 , pp. 3073-3081
    • Schierle, G.S.1    Leist, M.2    Martinou, J.C.3    Widner, H.4    Nicotera, P.5    Brundin, P.6
  • 122
    • 0033596556 scopus 로고    scopus 로고
    • Neuroprotective efficacy of combination therapy with two different antioxidants in rats subjected to transient focal ischemia
    • Schmid-Elsaesser, R.; Hungerhuber, E.; Zausinger, S.; Baethmann, A.; Reulen, H. J. Neuroprotective efficacy of combination therapy with two different antioxidants in rats subjected to transient focal ischemia. Brain Res. 816:471-479; 1999.
    • (1999) Brain Res. , vol.816 , pp. 471-479
    • Schmid-Elsaesser, R.1    Hungerhuber, E.2    Zausinger, S.3    Baethmann, A.4    Reulen, H.J.5
  • 123
    • 0030901162 scopus 로고    scopus 로고
    • Fluoro-Jade: A novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration
    • Schmued, L. C.; Albertson, C.; Slikker, W., Jr. Fluoro-Jade: A novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration. Brain Res. 751:37-46; 1997.
    • (1997) Brain Res. , vol.751 , pp. 37-46
    • Schmued, L.C.1    Albertson, C.2    Slikker W., Jr.3
  • 125
    • 0025088837 scopus 로고
    • Effects of intraventricular substantia nigra allografts as a function of donor age
    • Simonds, G. R.; Freed, W. J. Effects of intraventricular substantia nigra allografts as a function of donor age. Brain Res. 530:12-19; 1990.
    • (1990) Brain Res. , vol.530 , pp. 12-19
    • Simonds, G.R.1    Freed, W.J.2
  • 126
    • 0033606063 scopus 로고    scopus 로고
    • Delayed implantation of nigral grafts improves survival of dopamine neurones and rate of functional recovery
    • Sinclair, S. R.; Fawcett, J. W.; Dunnett, S. B. Delayed implantation of nigral grafts improves survival of dopamine neurones and rate of functional recovery. Neuroreport 10:1263-1267; 1999.
    • (1999) Neuroreport , vol.10 , pp. 1263-1267
    • Sinclair, S.R.1    Fawcett, J.W.2    Dunnett, S.B.3
  • 127
  • 128
    • 0029765443 scopus 로고    scopus 로고
    • Role of uncoupled and non-coupled oxidations in maintenance of safely low levels of oxygen and its one-electron reductants
    • Skulachev, V. P. Role of uncoupled and non-coupled oxidations in maintenance of safely low levels of oxygen and its one-electron reductants. Q. Rev. Biophys. 29: 169-202; 1996.
    • (1996) Q. Rev. Biophys. , vol.29 , pp. 169-202
    • Skulachev, V.P.1
  • 129
    • 0032487353 scopus 로고    scopus 로고
    • Co-grafted embryonic striatum increases the survival of grafted embryonic dopamine neurons
    • Sortwell, C. E.; Collier, T. J.; Sladek, J. R., Jr. Co-grafted embryonic striatum increases the survival of grafted embryonic dopamine neurons. J. Comp. Neurol. 399:530-540; 1998.
    • (1998) J. Comp. Neurol. , vol.399 , pp. 530-540
    • Sortwell, C.E.1    Collier, T.J.2    Sladek J.R., Jr.3
  • 130
    • 0028894069 scopus 로고
    • Comparison of the effects of the neurotrophins on the morphological structure of dopaminergic neurons in cultures of rat substantia nigra
    • Studer, L.; Spenger, C.; Seiler, R. W.; Altar, C. A.; Lindsay, R. M.; Hyman, C. Comparison of the effects of the neurotrophins on the morphological structure of dopaminergic neurons in cultures of rat substantia nigra. Eur. J. Neurosci. 7:223-233; 1995.
    • (1995) Eur. J. Neurosci. , vol.7 , pp. 223-233
    • Studer, L.1    Spenger, C.2    Seiler, R.W.3    Altar, C.A.4    Lindsay, R.M.5    Hyman, C.6
  • 131
    • 0032457981 scopus 로고    scopus 로고
    • Growth/differentiation factor 5 and glial cell line-derived neurotrophic factor enhance survival and function of dopaminergic grafts in a rat model of Parkinson's disease
    • Sullivan, A. M.; Pohl, J.; Blunt, S. B. Growth/differentiation factor 5 and glial cell line-derived neurotrophic factor enhance survival and function of dopaminergic grafts in a rat model of Parkinson's disease. Eur. J. Neurosci. 10:3681-3688; 1998.
    • (1998) Eur. J. Neurosci. , vol.10 , pp. 3681-3688
    • Sullivan, A.M.1    Pohl, J.2    Blunt, S.B.3
  • 132
    • 0020421621 scopus 로고
    • The projections of the ventral tegmental area and adjacent regions: A combined fluorescent retrograde tracer and immunofluoresence study in the rat
    • Swanson, L. W. The projections of the ventral tegmental area and adjacent regions: A combined fluorescent retrograde tracer and immunofluoresence study in the rat. Brain Res. Bull. 9:321-412; 1982.
    • (1982) Brain Res. Bull. , vol.9 , pp. 321-412
    • Swanson, L.W.1
  • 133
    • 0029922989 scopus 로고    scopus 로고
    • Evaluation of the relative contribution of nitric oxide and peroxynitrite to the suppression of mitochondrial respiration in immunostimulated macrophages using a manganese mesoporphyrin superoxide dismutase mimetic and peroxynitrite scavenger
    • Szabo, C.; Day, B. J.; Salzman, A. L. Evaluation of the relative contribution of nitric oxide and peroxynitrite to the suppression of mitochondrial respiration in immunostimulated macrophages using a manganese mesoporphyrin superoxide dismutase mimetic and peroxynitrite scavenger. FEBS Lett. 381:82-86; 1996.
    • (1996) FEBS Lett. , vol.381 , pp. 82-86
    • Szabo, C.1    Day, B.J.2    Salzman, A.L.3
  • 134
    • 0032135785 scopus 로고    scopus 로고
    • Fetal tissue transplantation in Parkinson's disease
    • Tabbal, S.; Fahn, S.; Frucht, S. Fetal tissue transplantation in Parkinson's disease. Curr. Opin. Neurol. 11:341-349; 1998.
    • (1998) Curr. Opin. Neurol. , vol.11 , pp. 341-349
    • Tabbal, S.1    Fahn, S.2    Frucht, S.3
  • 135
    • 0028953328 scopus 로고
    • Basic fibroblast growth factor increases dopaminergic graft survival and function in a rat model of Parkinson's disease
    • Takayama, H.; Ray, J.; Raymon, H. K.; Baird, A.; Hogg, J.; Fisher, L. J.; Gage, F. H. Basic fibroblast growth factor increases dopaminergic graft survival and function in a rat model of Parkinson's disease. Nat. Med. 1:53-58; 1995.
    • (1995) Nat. Med. , vol.1 , pp. 53-58
    • Takayama, H.1    Ray, J.2    Raymon, H.K.3    Baird, A.4    Hogg, J.5    Fisher, L.J.6    Gage, F.H.7
  • 136
    • 0028074242 scopus 로고
    • Inhibitory effects of calcium antagonists on mitochondrial swelling induced by lipid peroxidation or arachidonic acid in the rat brain in vitro
    • Takei, M.; Hiramatsu, M.; Mori, A. Inhibitory effects of calcium antagonists on mitochondrial swelling induced by lipid peroxidation or arachidonic acid in the rat brain in vitro. Neurochem. Res. 19:1199-1206; 1994.
    • (1994) Neurochem. Res. , vol.19 , pp. 1199-1206
    • Takei, M.1    Hiramatsu, M.2    Mori, A.3
  • 137
    • 0028304261 scopus 로고
    • Postnatal changes in the distribution and morphology of rat substantia nigra dopaminergic neurons
    • Tepper, J. M.; Damlama, M.; Trent, F. Postnatal changes in the distribution and morphology of rat substantia nigra dopaminergic neurons. Neuroscience 60:469-477; 1994.
    • (1994) Neuroscience , vol.60 , pp. 469-477
    • Tepper, J.M.1    Damlama, M.2    Trent, F.3
  • 138
    • 0032575750 scopus 로고    scopus 로고
    • Caspases: Enemies within
    • Thornberry, N. A.; Lazebnik, Y. Caspases: Enemies within. Science 281:1312-1316; 1998.
    • (1998) Science , vol.281 , pp. 1312-1316
    • Thornberry, N.A.1    Lazebnik, Y.2
  • 140
    • 0032482129 scopus 로고    scopus 로고
    • Sustained pharmacological inhibition of nitric oxide synthase does not affect the survival of intrastriatal rat fetal mesencephalic transplants
    • Van Muiswinkel, F. L.; Drukarch, B.; Steinbusch, H. W.; De Vente, J. Sustained pharmacological inhibition of nitric oxide synthase does not affect the survival of intrastriatal rat fetal mesencephalic transplants. Brain Res. 792:48-58; 1998.
    • (1998) Brain Res. , vol.792 , pp. 48-58
    • Van Muiswinkel, F.L.1    Drukarch, B.2    Steinbusch, H.W.3    De Vente, J.4
  • 141
    • 0031768858 scopus 로고    scopus 로고
    • The development of intracerebral cell-suspension implants is influenced by the grafting medium
    • Watts, C.; Caldwell, M. A.; Dunnett, S. B. The development of intracerebral cell-suspension implants is influenced by the grafting medium. Cell Transplant. 7:573-583; 1998.
    • (1998) Cell Transplant , vol.7 , pp. 573-583
    • Watts, C.1    Caldwell, M.A.2    Dunnett, S.B.3
  • 142
    • 0012058539 scopus 로고    scopus 로고
    • The method of preparation of the donor tissue affects functional outcome in a rodent model of Parkinson's disease
    • Watts, C.; Hurelbrink, C.; Dunnett, S. B. The method of preparation of the donor tissue affects functional outcome in a rodent model of Parkinson's disease. Soc Neurosci. Abstr. 223.1. 1998.
    • (1998) Soc Neurosci. Abstr. , pp. 2231
    • Watts, C.1    Hurelbrink, C.2    Dunnett, S.B.3
  • 143
    • 0030804272 scopus 로고    scopus 로고
    • Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury
    • Yakovlev, A. G.; Knoblach, S. M.; Fan, L.; Fox, G. B.; Goodnight, R.; Faden, A. I. Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury. J. Neurosci. 17:7415-7424; 1997.
    • (1997) J. Neurosci. , vol.17 , pp. 7415-7424
    • Yakovlev, A.G.1    Knoblach, S.M.2    Fan, L.3    Fox, G.B.4    Goodnight, R.5    Faden, A.I.6
  • 145
    • 0026522028 scopus 로고
    • Neuroprotective effects of phenyl-t-butyl-nitrone in gerbil global brain ischemia and in cultured rat cerebellar neurons
    • Yue, T. L.; Gu, J. L.; Lysko, P. G.; Cheng, H. Y.; Barone, F. C.; Feuerstein, G. Neuroprotective effects of phenyl-t-butyl-nitrone in gerbil global brain ischemia and in cultured rat cerebellar neurons. Brain Res. 574:193-197; 1992.
    • (1992) Brain Res. , vol.574 , pp. 193-197
    • Yue, T.L.1    Gu, J.L.2    Lysko, P.G.3    Cheng, H.Y.4    Barone, F.C.5    Feuerstein, G.6
  • 146
    • 0032192440 scopus 로고    scopus 로고
    • Localization of ionotropic and metabotropic glutamate receptors in distinct neuronal elements of the rat substantia nigra
    • Yung, K. K. Localization of ionotropic and metabotropic glutamate receptors in distinct neuronal elements of the rat substantia nigra. Neurochem. Int. 33:313-326; 1998.
    • (1998) Neurochem. Int. , vol.33 , pp. 313-326
    • Yung, K.K.1
  • 147
    • 0032192007 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor improves survival of dopaminergic neurons in transplants of fetal ventral mesencephalic tissue
    • Yurek, D. M. Glial cell line-derived neurotrophic factor improves survival of dopaminergic neurons in transplants of fetal ventral mesencephalic tissue. Exp. Neurol. 153:195-202; 1998.
    • (1998) Exp. Neurol. , vol.153 , pp. 195-202
    • Yurek, D.M.1
  • 148
    • 0025125222 scopus 로고
    • Embryonic mesencephalic and striatal co-grafts: Development of grafted dopamine neurons and functional recovery
    • Yurek, D. M.; Collier, T. J.; Sladek, J. R., Jr. Embryonic mesencephalic and striatal co-grafts: Development of grafted dopamine neurons and functional recovery. Exp. Neurol. 109:191-199; 1990.
    • (1990) Exp. Neurol. , vol.109 , pp. 191-199
    • Yurek, D.M.1    Collier, T.J.2    Sladek J.R., Jr.3
  • 149
    • 0030053470 scopus 로고    scopus 로고
    • BDNF enhances the functional reinnervation of the striatum by grafted fetal dopamine neurons
    • Yurek, D. M.; Lu, W.; Hipkens, S.; Wiegand, S. J. BDNF enhances the functional reinnervation of the striatum by grafted fetal dopamine neurons. Exp. Neurol. 137:105-118; 1996.
    • (1996) Exp. Neurol. , vol.137 , pp. 105-118
    • Yurek, D.M.1    Lu, W.2    Hipkens, S.3    Wiegand, S.J.4
  • 150
    • 0032498835 scopus 로고    scopus 로고
    • Growth factors improve immediate survival of embryonic dopamine neurons after transplantation into rats
    • Zawada, W. M.; Zastrow, D. J.; Clarkson, E. D.; Adams, F. S.; Bell, K. P.; Freed, C. R. Growth factors improve immediate survival of embryonic dopamine neurons after transplantation into rats. Brain Res. 786:96-103; 1998.
    • (1998) Brain Res. , vol.786 , pp. 96-103
    • Zawada, W.M.1    Zastrow, D.J.2    Clarkson, E.D.3    Adams, F.S.4    Bell, K.P.5    Freed, C.R.6
  • 151
    • 0030158340 scopus 로고    scopus 로고
    • Altered motor function and graft survival produced by basic fibroblast growth factor in rats with 6-OHDA lesions and fetal ventral mesencephalic grafts are associated with glial proliferation
    • Zeng, B. Y.; Jenner, P.; Marsden, C. D. Altered motor function and graft survival produced by basic fibroblast growth factor in rats with 6-OHDA lesions and fetal ventral mesencephalic grafts are associated with glial proliferation. Exp. Neurol. 139:214-226; 1996.
    • (1996) Exp. Neurol. , vol.139 , pp. 214-226
    • Zeng, B.Y.1    Jenner, P.2    Marsden, C.D.3


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