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Volumn 3, Issue 6, 2000, Pages 537-544

Cell replacement therapies for central nervous system disorders

Author keywords

[No Author keywords available]

Indexed keywords

ADOPTIVE IMMUNOTHERAPY; BASAL GANGLION; BRAIN FUNCTION; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM DISEASE; DOPAMINERGIC SYSTEM; EPILEPSY; HUMAN; HUNTINGTON CHOREA; NEUROPROTECTION; NEUROTRANSMISSION; PARKINSON DISEASE; PRIORITY JOURNAL; REVIEW; STROKE;

EID: 0034032642     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/75705     Document Type: Review
Times cited : (812)

References (61)
  • 1
    • 0025733852 scopus 로고
    • The reconstruction of cerebellar circuits
    • Sotelo, C. & Alvarado-Mallart, R. M. The reconstruction of cerebellar circuits. Trends Neurosci. 14, 350-355 (1991).
    • (1991) Trends Neurosci. , vol.14 , pp. 350-355
    • Sotelo, C.1    Alvarado-Mallart, R.M.2
  • 2
    • 0029953299 scopus 로고    scopus 로고
    • Embryonic neurons transplanted to regions of targeted photolytic cell death in adult mouse somatosensory cortex re-form specific callosal projections
    • Hernit-Grant, C. S. & Macklis, J. D. Embryonic neurons transplanted to regions of targeted photolytic cell death in adult mouse somatosensory cortex re-form specific callosal projections. Exp. Neurol 139, 131-142 (1996).
    • (1996) Exp. Neurol , vol.139 , pp. 131-142
    • Hernit-Grant, C.S.1    Macklis, J.D.2
  • 3
    • 0030881885 scopus 로고    scopus 로고
    • Multipotent neural precursors can differentiate toward replacement of neurons undergoing targeted apoptotic degeneration in adult mouse neocortex
    • Snyder, Y. E., Yoon, C., Flax, J. D. & Macklis, J. D. Multipotent neural precursors can differentiate toward replacement of neurons undergoing targeted apoptotic degeneration in adult mouse neocortex. Proc. Natl. Acad. Sci. USA 94, 11663-11668 (1997).
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 11663-11668
    • Snyder, Y.E.1    Yoon, C.2    Flax, J.D.3    Macklis, J.D.4
  • 5
    • 0030779992 scopus 로고    scopus 로고
    • Use of Schwann cells to induce repair of adult CNS tracts
    • Raisman, G. Use of Schwann cells to induce repair of adult CNS tracts. Rev. Neurol. (Paris) 153, 521-525 (1997).
    • (1997) Rev. Neurol. (Paris) , vol.153 , pp. 521-525
    • Raisman, G.1
  • 6
    • 0031465925 scopus 로고    scopus 로고
    • Repair of myelin disease: Strategies and progress in animal models
    • Duncan, I. D., Grever, W. E. & Zhang, S.-C. Repair of myelin disease: strategies and progress in animal models. Mol. Med. Today 3, 554-561 (1997).
    • (1997) Mol. Med. Today , vol.3 , pp. 554-561
    • Duncan, I.D.1    Grever, W.E.2    Zhang, S.-C.3
  • 7
    • 0028070946 scopus 로고
    • Dopaminergic neural grafts after fifteen years: Results and perspectives
    • Herman, J. P. & Abrous, N. D. Dopaminergic neural grafts after fifteen years: Results and perspectives. Prog. Neurobiol. 44, 1-35 (1994).
    • (1994) Prog. Neurobiol. , vol.44 , pp. 1-35
    • Herman, J.P.1    Abrous, N.D.2
  • 9
    • 0002645391 scopus 로고
    • eds. Dunnett, S. B. and Björklund, A. Raven, New York
    • Annett, L. E. in Functional Neural Transplantation (eds. Dunnett, S. B. and Björklund, A.) 71-102 (Raven, New York, 1994).
    • (1994) Functional Neural Transplantation , pp. 71-102
    • Annett, L.E.1
  • 10
    • 0026939784 scopus 로고
    • Dopaminergic transplants in experimental parkinsonism: Cellular mechanisms of graft-induced functional recovery
    • Björklund, A. Dopaminergic transplants in experimental parkinsonism: Cellular mechanisms of graft-induced functional recovery. Curr. Opin. Neurobiol 2, 683-689 (1992).
    • (1992) Curr. Opin. Neurobiol , vol.2 , pp. 683-689
    • Björklund, A.1
  • 11
    • 0024409802 scopus 로고
    • Time-course of recovery of dopamine neuron activity during reinnervation of the denervated striatum by fetal mesencephalic grafts as assessed by in vivo voltammetry
    • Forni, C. et al. Time-course of recovery of dopamine neuron activity during reinnervation of the denervated striatum by fetal mesencephalic grafts as assessed by in vivo voltammetry. Exp. Brain Res. 76, 75-87 (1989).
    • (1989) Exp. Brain Res. , vol.76 , pp. 75-87
    • Forni, C.1
  • 12
    • 0023191549 scopus 로고
    • Dopamine-rich grafts ameliorate whole body motor asymmetry and sensory neglect but not independent limb use in rats with 6-hydroxydopamine lesions
    • Dunnett, S. B., Whishaw, I. Q., Rogers, D. C. & Jones, G. H. Dopamine-rich grafts ameliorate whole body motor asymmetry and sensory neglect but not independent limb use in rats with 6-hydroxydopamine lesions. Brain Res. 415, 63-78 (1987).
    • (1987) Brain Res. , vol.415 , pp. 63-78
    • Dunnett, S.B.1    Whishaw, I.Q.2    Rogers, D.C.3    Jones, G.H.4
  • 13
    • 0033054208 scopus 로고    scopus 로고
    • Intranigral transplants of GABA-rich striatal tissue induce behavioral recovery in the rat parkinson model and promote the effects obtained by intrastriatal dopaminergic transplants
    • Winkler, C., Bentlage, C., Nikkhah, G., Samii, M. & Björklund, A. Intranigral transplants of GABA-rich striatal tissue induce behavioral recovery in the rat Parkinson model and promote the effects obtained by intrastriatal dopaminergic transplants. Exp. Neurol. 155, 165-186 (1999).
    • (1999) Exp. Neurol. , vol.155 , pp. 165-186
    • Winkler, C.1    Bentlage, C.2    Nikkhah, G.3    Samii, M.4    Björklund, A.5
  • 14
    • 0026089918 scopus 로고
    • Electrophysiological characteristics of cells within mesencephalon suspension grafts
    • Fisher, L. J., Young, S. J., Tepper, J. M., Groves, P. M. & Gage, F. H. Electrophysiological characteristics of cells within mesencephalon suspension grafts. Neuroscience 40, 109-122 (1991).
    • (1991) Neuroscience , vol.40 , pp. 109-122
    • Fisher, L.J.1    Young, S.J.2    Tepper, J.M.3    Groves, P.M.4    Gage, F.H.5
  • 15
    • 0024431280 scopus 로고
    • Host afferents into intrastriatal transplants of fetal ventral mesencephalon
    • Doucet, G. et al. Host afferents into intrastriatal transplants of fetal ventral mesencephalon. Exp. Neurol. 106, 1-19 (1989).
    • (1989) Exp. Neurol. , vol.106 , pp. 1-19
    • Doucet, G.1
  • 16
    • 0030041034 scopus 로고    scopus 로고
    • Fetal nigral transplantation as a therapy for Parkinson's disease
    • Olanow, C. W., Kordower, J. H. & Freeman, T. B. Fetal nigral transplantation as a therapy for Parkinson's disease. Trends Neurosci. 19, 102-109 (1996).
    • (1996) Trends Neurosci. , vol.19 , pp. 102-109
    • Olanow, C.W.1    Kordower, J.H.2    Freeman, T.B.3
  • 17
    • 0033405852 scopus 로고    scopus 로고
    • Cerebral implantation in movement disorders: State of the art
    • Lindvall, O. Cerebral implantation in movement disorders: State of the art. Mov. Disord. 14, 201-205 (1999).
    • (1999) Mov. Disord. , vol.14 , pp. 201-205
    • Lindvall, O.1
  • 18
    • 0033598429 scopus 로고    scopus 로고
    • Use of placebo surgery in controlled trials of cellular-based therapy for Parkinson's disease
    • Freeman, T. B. et al. Use of placebo surgery in controlled trials of cellular-based therapy for Parkinson's disease. N. Engl. J. Med. 341, 988-992 (1999).
    • (1999) N. Engl. J. Med. , vol.341 , pp. 988-992
    • Freeman, T.B.1
  • 19
    • 0028911848 scopus 로고
    • Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease
    • Kordower, J. H. et al. Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease. N. Engl. J. Med. 332, 1118-1124 (1995).
    • (1995) N. Engl. J. Med. , vol.332 , pp. 1118-1124
    • Kordower, J.H.1
  • 20
    • 0031922226 scopus 로고    scopus 로고
    • Fetal nigral grafts survive and mediate clinical benefit in a patient with Parkinson's disease
    • Kordower, J. H. et al. Fetal nigral grafts survive and mediate clinical benefit in a patient with Parkinson's disease. Mov. Disord. 13, 383-393 (1998).
    • (1998) Mov. Disord. , vol.13 , pp. 383-393
    • Kordower, J.H.1
  • 22
    • 0028872929 scopus 로고
    • Functional repair of striatal systems by neural transplants: Evidence for circuit reconstruction
    • Dunnett, S. B. Functional repair of striatal systems by neural transplants: evidence for circuit reconstruction. Behav. Brain. Res. 66, 133-142 (1995).
    • (1995) Behav. Brain. Res. , vol.66 , pp. 133-142
    • Dunnett, S.B.1
  • 23
    • 0031777250 scopus 로고    scopus 로고
    • Functional integration of striatal allografts in a primate model of Huntington's disease
    • Kendall, A. L. et al. Functional integration of striatal allografts in a primate model of Huntington's disease. Nat. Med. 4, 727-729 (1998).
    • (1998) Nat. Med. , vol.4 , pp. 727-729
    • Kendall, A.L.1
  • 24
    • 0031902287 scopus 로고    scopus 로고
    • Fetal striatal allografts reverse cognitive deficits in a primate model of Huntington disease
    • Palfi, S. P. et al. Fetal striatal allografts reverse cognitive deficits in a primate model of Huntington disease. Nat. Med. 4, 963-966 (1998).
    • (1998) Nat. Med. , vol.4 , pp. 963-966
    • Palfi, S.P.1
  • 26
    • 0029815726 scopus 로고    scopus 로고
    • A neostriatal habit learning system in humans
    • Knowlton, B. J., Mangles, J. A & Squire, L. R. A neostriatal habit learning system in humans. Science 273, 1399-1402 (1996).
    • (1996) Science , vol.273 , pp. 1399-1402
    • Knowlton, B.J.1    Mangles, J.A.2    Squire, L.R.3
  • 28
    • 0030953742 scopus 로고    scopus 로고
    • Neuropsychological functioning following fetal striatal transplantation in Huntington's chorea: Three case presentations
    • Philpott, L. M. et al. Neuropsychological functioning following fetal striatal transplantation in Huntington's chorea: Three case presentations. Cell Transplantation 6, 203-212 (1997).
    • (1997) Cell Transplantation , vol.6 , pp. 203-212
    • Philpott, L.M.1
  • 29
    • 0034009388 scopus 로고    scopus 로고
    • Safety and tolerability assessment of intrastriatal neural allografts in five patients with Huntington's disease
    • Bachoud-Lévi, A.-C. et al. Safety and tolerability assessment of intrastriatal neural allografts in five patients with Huntington's disease. Exp. Neurol. 161, 194-202 (2000).
    • (2000) Exp. Neurol. , vol.161 , pp. 194-202
    • Bachoud-Lévi, A.-C.1
  • 30
    • 0033600245 scopus 로고    scopus 로고
    • Emerging insights into the genesis of epilepsy
    • McNamara, J. O. Emerging insights into the genesis of epilepsy. Nature 399 (suppl.), A15-22 (1999).
    • (1999) Nature , vol.399 , Issue.SUPPL.
    • McNamara, J.O.1
  • 32
    • 0027998582 scopus 로고
    • Seizure suppression in kindling epilepsy by intracerebral implants of GABA - But not by noradrenalin-releasing polymer matrices
    • Kokaia, M et al. Seizure suppression in kindling epilepsy by intracerebral implants of GABA - but not by noradrenalin-releasing polymer matrices. Exp. Brain Res. 100, 385-394 (1994).
    • (1994) Exp. Brain Res. , vol.100 , pp. 385-394
    • Kokaia, M.1
  • 33
    • 2642702860 scopus 로고    scopus 로고
    • Seizure suppression in kindling epilepsy by grafts of fetal GABAergic neurons in rat substantia nigra
    • Löscher, W., Ebert, U., Lehmann, H., Rosenthal, C. & Nikkhah, G. Seizure suppression in kindling epilepsy by grafts of fetal GABAergic neurons in rat substantia nigra. J. Neurosci. Res. 15, 196-209 (1998).
    • (1998) J. Neurosci. Res. , vol.15 , pp. 196-209
    • Löscher, W.1    Ebert, U.2    Lehmann, H.3    Rosenthal, C.4    Nikkhah, G.5
  • 35
    • 0029877193 scopus 로고    scopus 로고
    • Contrasting effects of fetal CA1 and CA3 hippocampal grafts on deficits in spatial learning and working memory induced by global cerebral ischaemia in rats
    • Hodges, H. et al. Contrasting effects of fetal CA1 and CA3 hippocampal grafts on deficits in spatial learning and working memory induced by global cerebral ischaemia in rats. Neuroscience 72, 959-988 (1996).
    • (1996) Neuroscience , vol.72 , pp. 959-988
    • Hodges, H.1
  • 36
    • 0029867899 scopus 로고    scopus 로고
    • Fetal neocortical tissue blocks implanted in brain infarcts of adult rats interconnect with the host brain
    • Sørensen, J. C., Grabowski, M., Zimmer, J. & Johansson, B. B. Fetal neocortical tissue blocks implanted in brain infarcts of adult rats interconnect with the host brain. Exp. Neurol. 138, 227-235 (1996).
    • (1996) Exp. Neurol. , vol.138 , pp. 227-235
    • Sørensen, J.C.1    Grabowski, M.2    Zimmer, J.3    Johansson, B.B.4
  • 37
    • 0030963071 scopus 로고    scopus 로고
    • Neural grafting to experimental neocortical infarcts improves behavioral outcome and reduces thalamic atrophy in rats housed in enriched but not in standard environments
    • Mattsson, B., Sørensen, J. C., Zimmer, J. & Johansson, B. B. Neural grafting to experimental neocortical infarcts improves behavioral outcome and reduces thalamic atrophy in rats housed in enriched but not in standard environments. Stroke 28, 1225-1232 (1997).
    • (1997) Stroke , vol.28 , pp. 1225-1232
    • Mattsson, B.1    Sørensen, J.C.2    Zimmer, J.3    Johansson, B.B.4
  • 38
    • 0032006347 scopus 로고    scopus 로고
    • Transplantation of cryopreserved human embryonal carcinoma-derived neurons (NT2N cells) promotes functional recovery in ischemic rats
    • Borlongan, C. V., Tajima, Y., Trojanowski, J. Q., Lee, V. M.-Y. & Sanberg, P. Transplantation of cryopreserved human embryonal carcinoma-derived neurons (NT2N cells) promotes functional recovery in ischemic rats. Exp. Neurol. 149, 310-321 (1998).
    • (1998) Exp. Neurol. , vol.149 , pp. 310-321
    • Borlongan, C.V.1    Tajima, Y.2    Trojanowski, J.Q.3    Lee, V.M.-Y.4    Sanberg, P.5
  • 39
    • 0032538964 scopus 로고    scopus 로고
    • Cerebral ischemia and CNS transplantation: Differential effects of grafted fetal rat striatal cells and human neurons derived from a clonal cell line
    • Borlongan, C. V., Tajima, Y, Trojanowski, J. Q., Lee, V. M.-Y. & Sanberg, P. Cerebral ischemia and CNS transplantation: differential effects of grafted fetal rat striatal cells and human neurons derived from a clonal cell line. Neuroreport 9, 3703-3709 (1998).
    • (1998) Neuroreport , vol.9 , pp. 3703-3709
    • Borlongan, C.V.1    Tajima, Y.2    Trojanowski, J.Q.3    Lee, V.M.-Y.4    Sanberg, P.5
  • 40
    • 0031587271 scopus 로고    scopus 로고
    • Recovery of spatial learning by grafts of a conditionally immortalized hippocampal neuroepithelial cell line into the ischaemia-lesioned hippocampus
    • Sinden, J. D. et al. Recovery of spatial learning by grafts of a conditionally immortalized hippocampal neuroepithelial cell line into the ischaemia-lesioned hippocampus. Neuroscience 81, 599-608 (1997).
    • (1997) Neuroscience , vol.81 , pp. 599-608
    • Sinden, J.D.1
  • 41
    • 33644684826 scopus 로고    scopus 로고
    • Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats
    • Studer, L., Tabar, V. & McKay, R. D. G. Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats. Nat. Neurosci. 1, 290-295 (1998).
    • (1998) Nat. Neurosci. , vol.1 , pp. 290-295
    • Studer, L.1    Tabar, V.2    McKay, R.D.G.3
  • 42
    • 0032007097 scopus 로고    scopus 로고
    • Differentiation of mesencephalic progenitor cells into dopaminergic neurons by cytokines
    • Ling, Z. D., Potter, E. D., Lipton, J. W. & Carvey, P. M. Differentiation of mesencephalic progenitor cells into dopaminergic neurons by cytokines. Exp. Neurol. 149, 411-423 (1998).
    • (1998) Exp. Neurol. , vol.149 , pp. 411-423
    • Ling, Z.D.1    Potter, E.D.2    Lipton, J.W.3    Carvey, P.M.4
  • 43
    • 0032918328 scopus 로고    scopus 로고
    • Cytokine-induced conversion of mesencephalic-derived progenitor cells into dopamine neurons
    • Potter, E. D., Ling, Z. D. & Carvey, P. M. Cytokine-induced conversion of mesencephalic-derived progenitor cells into dopamine neurons. Cell Tissue Res. 296, 235-246 (1999).
    • (1999) Cell Tissue Res. , vol.296 , pp. 235-246
    • Potter, E.D.1    Ling, Z.D.2    Carvey, P.M.3
  • 44
    • 0032980340 scopus 로고    scopus 로고
    • Induction of a midbrain dopaminergic phenotype in Nurr1-overexpressing neural stem cells by type 1 astrocytes
    • Wagner, J. et al. Induction of a midbrain dopaminergic phenotype in Nurr1-overexpressing neural stem cells by type 1 astrocytes. Nat. Biotech. 17, 653-659 (1999).
    • (1999) Nat. Biotech. , vol.17 , pp. 653-659
    • Wagner, J.1
  • 45
    • 0026011993 scopus 로고
    • Specific reinnervation of lesioned mouse striatum by grafted mesencephalic dopaminergic neurons
    • Zuddas, A., Corsini, G. U., Barker, J. L., Kopin, I. J. & di Porzio, U. Specific reinnervation of lesioned mouse striatum by grafted mesencephalic dopaminergic neurons. Eur. J. Neurosci. 3, 72-85 (1991).
    • (1991) Eur. J. Neurosci. , vol.3 , pp. 72-85
    • Zuddas, A.1    Corsini, G.U.2    Barker, J.L.3    Kopin, I.J.4    Di Porzio, U.5
  • 46
    • 0027979793 scopus 로고
    • Target and neurotransmitter specificity of fetal central nervous system transplants: Importance for functional reinnervation
    • Hudson, J. L., Bickford, P., Johansson, M., Hoffer, B. J. & Strömberg, I. Target and neurotransmitter specificity of fetal central nervous system transplants: Importance for functional reinnervation. J. Neurosci. 14, 283-290 (1994).
    • (1994) J. Neurosci. , vol.14 , pp. 283-290
    • Hudson, J.L.1    Bickford, P.2    Johansson, M.3    Hoffer, B.J.4    Strömberg, I.5
  • 47
    • 0033593304 scopus 로고    scopus 로고
    • Progression from extrinsic to intrinsic signaling in cell fate specification: A view from the nervous system
    • Edlund, T. & Jessell, T. Progression from extrinsic to intrinsic signaling in cell fate specification: A view from the nervous system. Cell 96, 211-224 (1999).
    • (1999) Cell , vol.96 , pp. 211-224
    • Edlund, T.1    Jessell, T.2
  • 48
    • 0031879531 scopus 로고    scopus 로고
    • Architecture and cell types of the adult subventricular zone: In search of the stem cells
    • Garcia-Verdugo, J. M., Doetch, F., Wichterle, H., Lim, D. A. & Alvarez-Buylla, A. Architecture and cell types of the adult subventricular zone: In search of the stem cells. J. Neurobiol. 36, 234-248 (1998).
    • (1998) J. Neurobiol. , vol.36 , pp. 234-248
    • Garcia-Verdugo, J.M.1    Doetch, F.2    Wichterle, H.3    Lim, D.A.4    Alvarez-Buylla, A.5
  • 49
    • 0034712047 scopus 로고    scopus 로고
    • Mammalian neural stem cells
    • Gage, F. H. Mammalian neural stem cells. Science 287, 1433-1438 (2000).
    • (2000) Science , vol.287 , pp. 1433-1438
    • Gage, F.H.1
  • 50
    • 0029967893 scopus 로고    scopus 로고
    • Differentiation of adult hippocampus-derived progenitors into olfactory neurons in vivo
    • Suhonen, J. O., Petersen, D. A., Ray, J. & Gage, F. H. Differentiation of adult hippocampus-derived progenitors into olfactory neurons in vivo. Nature 383, 624-627 (1996).
    • (1996) Nature , vol.383 , pp. 624-627
    • Suhonen, J.O.1    Petersen, D.A.2    Ray, J.3    Gage, F.H.4
  • 51
    • 0031771599 scopus 로고    scopus 로고
    • Engraftable human neural stem cells respond to developmental cues, replace neurons, and express foreign genes
    • Flax, J. D. et al. Engraftable human neural stem cells respond to developmental cues, replace neurons, and express foreign genes. Nat. Biotech. 16, 1033-1039 (1998).
    • (1998) Nat. Biotech. , vol.16 , pp. 1033-1039
    • Flax, J.D.1
  • 52
    • 0033565709 scopus 로고    scopus 로고
    • Site-specific migration and neuronal differentiation of human neural progenitor cells after transplantation in the adult rat brain
    • Fricker, R. A. et al. Site-specific migration and neuronal differentiation of human neural progenitor cells after transplantation in the adult rat brain. J. Neurosci. 19, 5990-6005 (1999).
    • (1999) J. Neurosci. , vol.19 , pp. 5990-6005
    • Fricker, R.A.1
  • 53
    • 0030012720 scopus 로고    scopus 로고
    • Selective hippocampal lesions differentially affect the phenotypic fate of transplanted neuronal precursor cells
    • Shihabuddin, L. S., Holets, V. R. & Whittemore, S. R. Selective hippocampal lesions differentially affect the phenotypic fate of transplanted neuronal precursor cells. Exp. Neurol. 139, 61-72 (1996).
    • (1996) Exp. Neurol. , vol.139 , pp. 61-72
    • Shihabuddin, L.S.1    Holets, V.R.2    Whittemore, S.R.3
  • 54
    • 0030007965 scopus 로고    scopus 로고
    • Conditionally immortalized neural progenitor cells grafted to the striatum exhibit site-specific neuronal differentiation and establish connections with the host globus pallidus
    • Lundberg, C., Winkler, C., Whittemore, S. R. & Björklund, A. Conditionally immortalized neural progenitor cells grafted to the striatum exhibit site-specific neuronal differentiation and establish connections with the host globus pallidus. Neurobiol. Disease 3, 33-50 (1996).
    • (1996) Neurobiol. Disease , vol.3 , pp. 33-50
    • Lundberg, C.1    Winkler, C.2    Whittemore, S.R.3    Björklund, A.4
  • 55
    • 0033491121 scopus 로고    scopus 로고
    • Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient
    • Piccini, P. et al. Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient. Nat. Neurosci. 2, 1137-1140 (1999).
    • (1999) Nat. Neurosci. , vol.2 , pp. 1137-1140
    • Piccini, P.1
  • 56
    • 0024450903 scopus 로고
    • The functional anatomy of basal ganglia disorders
    • Albin, R. L., Young, A. B. & Penney, J. B. The functional anatomy of basal ganglia disorders. Trends Neurosci. 12, 366-375 (1989).
    • (1989) Trends Neurosci. , vol.12 , pp. 366-375
    • Albin, R.L.1    Young, A.B.2    Penney, J.B.3
  • 57
    • 0026603230 scopus 로고
    • Anatomy and connectivity of intrastriatal striatal tansplants
    • Wictorin, K. Anatomy and connectivity of intrastriatal striatal tansplants. Prog. Neurobiol. 38, 611-639 (1992).
    • (1992) Prog. Neurobiol. , vol.38 , pp. 611-639
    • Wictorin, K.1
  • 58
    • 0030893208 scopus 로고    scopus 로고
    • Fetal raphe transplants reduce seizure severity in serotonin-depleted GEPRs
    • Clough, R. et al. Fetal raphe transplants reduce seizure severity in serotonin-depleted GEPRs. Neuroreport 8, 341-346 (1996).
    • (1996) Neuroreport , vol.8 , pp. 341-346
    • Clough, R.1
  • 59
    • 0031814752 scopus 로고    scopus 로고
    • Suppression of kindling epileptogenesis in rats by intrahippocampal cholinergic grafts
    • Ferencz, I. et al. Suppression of kindling epileptogenesis in rats by intrahippocampal cholinergic grafts. Eur. J. Neurosci. 10, 213-220 (1998).
    • (1998) Eur. J. Neurosci. , vol.10 , pp. 213-220
    • Ferencz, I.1
  • 60
    • 0034097604 scopus 로고    scopus 로고
    • Conditionally immortalized cell lines, engineered to produce and release GABA, modulate the development of behavioral seizures
    • Thompson, K. et al. Conditionally immortalized cell lines, engineered to produce and release GABA, modulate the development of behavioral seizures. Exp. Neurol. 161, 481-489 (2000).
    • (2000) Exp. Neurol. , vol.161 , pp. 481-489
    • Thompson, K.1
  • 61
    • 0029070781 scopus 로고
    • Influence of an enriched environment and cortical grafting on functional outcome in brain infarcts of adult rats
    • Grabowski, M., Sørensen, J. C., Mattsson, B, Zimmer, I. & Johansson, B. B. Influence of an enriched environment and cortical grafting on functional outcome in brain infarcts of adult rats. Exp. Neurol. 133, 96-102 (1995).
    • (1995) Exp. Neurol. , vol.133 , pp. 96-102
    • Grabowski, M.1    Sørensen, J.C.2    Mattsson, B.3    Zimmer, I.4    Johansson, B.B.5


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