-
1
-
-
0032889677
-
Redox regulation of cellular signalling
-
DOI 10.1016/S0898-6568(98)00037-0, PII S0898656898000370
-
Kamata H., Hirata H., Redox regulation of cellular signalling. Cellular Signalling 1999 11 1 1 14 2-s2.0-0032889677 10.1016/S0898-6568(98)00037-0 (Pubitemid 28546635)
-
(1999)
Cellular Signalling
, vol.11
, Issue.1
, pp. 1-14
-
-
Kamata, H.1
Hirata, H.2
-
2
-
-
0025756918
-
Enzymic mechanisms of superoxide production
-
2-s2.0-0025756918
-
Cross A. R., Jones O. T. G., Enzymic mechanisms of superoxide production. Biochimica et Biophysica Acta 1991 1057 3 281 298 2-s2.0-0025756918
-
(1991)
Biochimica et Biophysica Acta
, vol.1057
, Issue.3
, pp. 281-298
-
-
Cross, A.R.1
Jones, O.T.G.2
-
3
-
-
0033230607
-
Role of redox potential and reactive oxygen species in stress signaling
-
2-s2.0-0033230607
-
Adler V., Yin Z., Tew K. D., Ronai Z., Role of redox potential and reactive oxygen species in stress signaling. Oncogene 1999 18 45 6104 6111 2-s2.0-0033230607
-
(1999)
Oncogene
, vol.18
, Issue.45
, pp. 6104-6111
-
-
Adler, V.1
Yin, Z.2
Tew, K.D.3
Ronai, Z.4
-
4
-
-
0035584857
-
Reactive oxygen species, antioxidants, and the mammalian thioredoxin system
-
DOI 10.1016/S0891-5849(01)00724-9, PII S0891584901007249
-
Nordberg J., Arnér E. S. J., Reactive oxygen species, antioxidants, and the mammalian thioredoxin system. Free Radical Biology and Medicine 2001 31 11 1287 1312 2-s2.0-0035584857 10.1016/S0891-5849(01)00724-9 (Pubitemid 33145299)
-
(2001)
Free Radical Biology and Medicine
, vol.31
, Issue.11
, pp. 1287-1312
-
-
Nordberg, J.1
Arner, E.S.J.2
-
5
-
-
0036273095
-
A chemical perspective on the interplay between NO, reactive oxygen species, and Reactive Nitrogen Oxide Species
-
Espey M. G., Miranda K. M., Thomas D. D., Xavier S., Citrin D., Vitek M. P., Wink D. A., A chemical perspective on the interplay between NO, reactive oxygen species, and Reactive Nitrogen Oxide Species. Annals of the New York Academy of Sciences 2002 962 195 206 2-s2.0-0036273095 (Pubitemid 34592312)
-
(2002)
Annals of the New York Academy of Sciences
, vol.962
, pp. 195-206
-
-
Espey, M.G.1
Miranda, K.M.2
Thomas, D.D.3
Xavier, S.4
Citrin, D.5
Vitek, M.P.6
Wink, D.A.7
-
7
-
-
0030888919
-
Upregulation of protein-tyrosine nitration in the anterior horn cells of amyotrophic lateral sclerosis
-
Abe K., Pan L. H., Watanabe M., Konno H., Kato T., Itoyama Y., Upregulation of protein-tyrosine nitration in the anterior horn cells of amyotrophic lateral sclerosis. Neurological Research 1997 19 2 124 128 2-s2.0-0030888919 (Pubitemid 27190700)
-
(1997)
Neurological Research
, vol.19
, Issue.2
, pp. 124-128
-
-
Abe, K.1
Pan, L.-H.2
Watanabe, M.3
Konno, H.4
Kato, T.5
Itoyama, Y.6
-
8
-
-
0027293275
-
ALS, SOD and peroxynitrite [9]
-
DOI 10.1038/364584a0
-
Beckman J. S., Carson M., Smith C. D., Koppenol W. H., ALS, SOD and peroxynitrite. Nature 1993 364 6438 584 2-s2.0-0027293275 10.1038/364584a0 (Pubitemid 23274713)
-
(1993)
Nature
, vol.364
, Issue.6438
, pp. 584
-
-
Beckman, J.S.1
Carson, M.2
Smith, C.D.3
Koppenol, W.H.4
-
9
-
-
75149155060
-
Oxidative stress in ALS: Key role in motor neuron injury and therapeutic target
-
2-s2.0-75149155060 10.1016/j.freeradbiomed.2009.11.018
-
Barber S. C., Shaw P. J., Oxidative stress in ALS: key role in motor neuron injury and therapeutic target. Free Radical Biology and Medicine 2010 48 5 629 641 2-s2.0-75149155060 10.1016/j.freeradbiomed.2009.11.018
-
(2010)
Free Radical Biology and Medicine
, vol.48
, Issue.5
, pp. 629-641
-
-
Barber, S.C.1
Shaw, P.J.2
-
10
-
-
58849158293
-
Reactive nitrogen species: Molecular mechanisms and potential significance in health and disease
-
2-s2.0-58849158293 10.1089/ars.2007.1993
-
Martínez M. C., Andriantsitohaina R., Reactive nitrogen species: molecular mechanisms and potential significance in health and disease. Antioxidants and Redox Signaling 2009 11 3 669 702 2-s2.0-58849158293 10.1089/ars.2007.1993
-
(2009)
Antioxidants and Redox Signaling
, vol.11
, Issue.3
, pp. 669-702
-
-
Martínez, M.C.1
Andriantsitohaina, R.2
-
11
-
-
51749088156
-
Redox regulation of cell survival
-
2-s2.0-51749088156 10.1089/ars.2007.1957
-
Trachootham D., Lu W., Ogasawara M. A., Valle N. R. D., Huang P., Redox regulation of cell survival. Antioxidants and Redox Signaling 2008 10 8 1343 1374 2-s2.0-51749088156 10.1089/ars.2007.1957
-
(2008)
Antioxidants and Redox Signaling
, vol.10
, Issue.8
, pp. 1343-1374
-
-
Trachootham, D.1
Lu, W.2
Ogasawara, M.A.3
Valle, N.R.D.4
Huang, P.5
-
12
-
-
0036803249
-
Nanotransducers in cellular redox signaling: Modification of thiols by reactive oxygen and nitrogen species
-
DOI 10.1016/S0968-0004(02)02191-6, PII S0968000402021916
-
Cooper C. E., Patel R. P., Brookes P. S., Darley-Usmar V. M., Nanotransducers in cellular redox signaling: modification of thiols by reactive oxygen and nitrogen species. Trends in Biochemical Sciences 2002 27 10 489 492 2-s2.0-0036803249 10.1016/S0968-0004(02)02191-6 (Pubitemid 35279586)
-
(2002)
Trends in Biochemical Sciences
, vol.27
, Issue.10
, pp. 489-492
-
-
Cooper, C.E.1
Patel, R.P.2
Brookes, P.S.3
Darley-Usmar, V.M.4
-
13
-
-
0030936987
-
Redox regulation of cellular activation
-
DOI 10.1146/annurev.immunol.15.1.351
-
Nakamura H., Nakamura K., Yodoi J., Redox regulation of cellular activation. Annual Review of Immunology 1997 15 351 369 2-s2.0-0030936987 10.1146/annurev.immunol.15.1.351 (Pubitemid 27169285)
-
(1997)
Annual Review of Immunology
, vol.15
, pp. 351-369
-
-
Nakamura, H.1
Nakamura, K.2
Yodoi, J.3
-
14
-
-
0027194540
-
A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds
-
DOI 10.1038/364626a0
-
Lipton S. A., Choi Y. B., Pan Z. H., Lei S. Z., Chen H. S. V., Sucher N. J., Loscalzo J., Singel D. J., Stamler J. S., A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds. Nature 1993 364 6438 626 632 2-s2.0-0027194540 10.1038/364626a0 (Pubitemid 23274719)
-
(1993)
Nature
, vol.364
, Issue.6438
, pp. 626-632
-
-
Lipton, S.A.1
Choi, Y.-B.2
Pan, Z.-H.3
Lei, S.Z.4
Chen, H.-S.V.5
Sucher, N.J.6
Loscalzo, J.7
Singel, D.J.8
Stamler, J.S.9
-
15
-
-
33745013111
-
Oxidative stress and neurodegeneration: Where are we now?
-
DOI 10.1111/j.1471-4159.2006.03907.x
-
Halliwell B., Oxidative stress and neurodegeneration: where are we now? Journal of Neurochemistry 2006 97 6 1634 1658 2-s2.0-33745013111 10.1111/j.1471-4159.2006.03907.x (Pubitemid 43873658)
-
(2006)
Journal of Neurochemistry
, vol.97
, Issue.6
, pp. 1634-1658
-
-
Halliwell, B.1
-
16
-
-
84864960620
-
Redox regulation of cysteine-dependent enzymes in neurodegeneration
-
703164 10.1155/2012/703164
-
Guttmann R. P., Powell T. J., Redox regulation of cysteine-dependent enzymes in neurodegeneration. International Journal of Cell Biology 2012 2012 8 703164 10.1155/2012/703164
-
(2012)
International Journal of Cell Biology
, vol.2012
, pp. 8
-
-
Guttmann, R.P.1
Powell, T.J.2
-
17
-
-
0033524950
-
Increase in oxidized NO products and reduction in oxidized glutathione in cerebrospinal fluid from patients with sporadic form of amyotrophic lateral sclerosis
-
DOI 10.1016/S0304-3940(98)00986-0, PII S0304394098009860
-
Tohgi H., Abe T., Yamazaki K., Murata T., Ishizaki E., Isobe C., Increase in oxidized NO products and reduction in oxidized glutathione in cerebrospinal fluid from patients with sporadic form of amyotrophic lateral sclerosis. Neuroscience Letters 1999 260 3 204 206 2-s2.0-0033524950 10.1016/S0304-3940(98) 00986-0 (Pubitemid 29089196)
-
(1999)
Neuroscience Letters
, vol.260
, Issue.3
, pp. 204-206
-
-
Tohgi, H.1
Abe, T.2
Yamazaki, K.3
Murata, T.4
Ishizaki, E.5
Isobe, C.6
-
18
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
DOI 10.1038/362059a0
-
Rosen D. R., Siddique T., Patterson D., Figlewicz D. A., Sapp P., Hentati A., Donaldson D., Goto J., O'Regan J. P., Deng H. X., Rahmani Z., Krizus A., McKenna-Yasek D., Cayabyab A., Gaston S. M., Berger R., Tanzi R. E., Halperin J. J., Herzfeldt B., Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 1993 362 6415 59 62 2-s2.0-0027401203 10.1038/362059a0 (Pubitemid 23087289)
-
(1993)
Nature
, vol.362
, Issue.6415
, pp. 59-62
-
-
Rosen, D.R.1
Siddique, T.2
Patterson, D.3
Figlewicz, D.A.4
Sapp, P.5
Hentati, A.6
Donaldson, D.7
Goto, J.8
O'Regan, J.P.9
Deng, H.-X.10
Rahmani, Z.11
Krizus, A.12
McKenna-Yasek, D.13
Cayabyab, A.14
Gaston, S.M.15
Berger, R.16
Tanzi, R.E.17
Halperin, J.J.18
Herzfeldt, B.19
-
19
-
-
0031577722
-
Stability of mutant superoxide dismutase-1 associated with familial amyotrophic lateral sclerosis determines the manner of copper release and induction of thioredoxin in erythrocytes
-
DOI 10.1006/bbrc.1997.7804
-
Ogawa Y., Kosaka H., Nakanishi T., Shimizu A., Ohoi N., Shouji H., Yanagihara T., Sakoda S., Stability of mutant superoxide dismutase-1 associated with familial amyotrophic lateral sclerosis determines the manner of copper release and induction of thioredoxin in erythrocytes. Biochemical and Biophysical Research Communications 1997 241 2 251 257 2-s2.0-0031577722 10.1006/bbrc.1997.7804 (Pubitemid 28020088)
-
(1997)
Biochemical and Biophysical Research Communications
, vol.241
, Issue.2
, pp. 251-257
-
-
Ogawa, Y.1
Kosaka, H.2
Nakanishi, T.3
Shimizu, A.4
Ohoi, N.5
Shouji, H.6
Yanagihara, T.7
Sakoda, S.8
-
20
-
-
74249084267
-
Protein disulphide isomerase protects against protein aggregation and is S-nitrosylated in amyotrophic lateral sclerosis
-
2-s2.0-74249084267 10.1093/brain/awp267
-
Walker A. K., Farg M. A., Bye C. R., McLean C. A., Horne M. K., Atkin J. D., Protein disulphide isomerase protects against protein aggregation and is S-nitrosylated in amyotrophic lateral sclerosis. Brain 2010 133 1 105 116 2-s2.0-74249084267 10.1093/brain/awp267
-
(2010)
Brain
, vol.133
, Issue.1
, pp. 105-116
-
-
Walker, A.K.1
Farg, M.A.2
Bye, C.R.3
McLean, C.A.4
Horne, M.K.5
Atkin, J.D.6
-
21
-
-
84866253155
-
Redox regulation of protein function via cysteine S-nitrosylation and its relevance to neurodegenerative diseases
-
463756 10.1155/2012/463756
-
Akhtar M. W., Sunico C. R., Nakamura T., Lipton S. A., Redox regulation of protein function via cysteine S-nitrosylation and its relevance to neurodegenerative diseases. International Journal of Cell Biology 2012 2012 9 463756 10.1155/2012/463756
-
(2012)
International Journal of Cell Biology
, vol.2012
, pp. 9
-
-
Akhtar, M.W.1
Sunico, C.R.2
Nakamura, T.3
Lipton, S.A.4
-
22
-
-
60849093466
-
Current hypotheses for the underlying biology of amyotrophic lateral sclerosis
-
2-s2.0-60849093466 10.1002/ana.2'1543
-
Rothstein J. D., Current hypotheses for the underlying biology of amyotrophic lateral sclerosis. Annals of Neurology 2009 65 1 S3 S9 2-s2.0-60849093466 10.1002/ana.2'1543
-
(2009)
Annals of Neurology
, vol.65
, Issue.1
-
-
Rothstein, J.D.1
-
23
-
-
34250209501
-
Amyotrophic lateral sclerosis
-
DOI 10.1016/S0140-6736(07)60944-1, PII S0140673607609441
-
Mitchell J., Borasio G., Amyotrophic lateral sclerosis. Lancet 2007 369 9578 2031 2041 2-s2.0-34250209501 10.1016/S0140-6736(07)60944-1 (Pubitemid 46899183)
-
(2007)
Lancet
, vol.369
, Issue.9578
, pp. 2031-2041
-
-
Mitchell, J.1
Borasio, G.2
-
24
-
-
62749193868
-
Amyotrophic lateral sclerosis
-
2-s2.0-62749193868 10.1186/1750-1172-4-3
-
Wijesekera L. C., Leigh P. N., Amyotrophic lateral sclerosis. Orphanet Journal of Rare Diseases 2009 4 1 3 2-s2.0-62749193868 10.1186/1750-1172-4-3
-
(2009)
Orphanet Journal of Rare Diseases
, vol.4
, Issue.1
, pp. 3
-
-
Wijesekera, L.C.1
Leigh, P.N.2
-
25
-
-
0028097839
-
A controlled trial of riluzole in amyotrophic lateral sclerosis
-
DOI 10.1056/NEJM199403033300901
-
Bensimon G., Lacomblez L., Meininger V., A controlled trial of riluzole in amyotrophic lateral sclerosis. New England Journal of Medicine 1994 330 9 585 591 2-s2.0-0028097839 10.1056/NEJM199403033300901 (Pubitemid 24065791)
-
(1994)
New England Journal of Medicine
, vol.330
, Issue.9
, pp. 585-591
-
-
Bensimon, G.1
Lacomblez, L.2
Meininger, V.3
-
26
-
-
34250208597
-
Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND)
-
DOI 10.1002/14651858.CD001447.pub2
-
Miller R. G., Mitchell J. D., Lyon M., Moore D. H., Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND). Cochrane Database of Systematic Reviews 2007 1 2-s2.0-34250208597 10.1002/14651858. CD001447.pub2 CD001447 (Pubitemid 351835443)
-
(2007)
Cochrane Database of Systematic Reviews
, Issue.1
-
-
Miller, R.G.1
Mitchell, J.D.2
Lyon, M.3
Moore, D.H.4
-
27
-
-
76749096341
-
Association of smoking with amyotrophic lateral sclerosis risk and survival in men and women: A prospective study
-
2-s2.0-76749096341 10.1186/1471-2377-10-6
-
Alonso A., Logroscino G., Jick S. S., Hernán M. A., Association of smoking with amyotrophic lateral sclerosis risk and survival in men and women: a prospective study. BMC Neurology 2010 10 1 6 2-s2.0-76749096341 10.1186/1471-2377-10-6
-
(2010)
BMC Neurology
, vol.10
, Issue.1
, pp. 6
-
-
Alonso, A.1
Logroscino, G.2
Jick, S.S.3
Hernán, M.A.4
-
28
-
-
29144518581
-
ALS syndrome in patients with HIV-1 infection
-
DOI 10.1016/j.jns.2005.09.005, PII S0022510X05003370
-
Verma A., Berger J. R., ALS syndrome in patients with HIV-1 infection. Journal of the Neurological Sciences 2006 240 1-2 59 64 2-s2.0-29144518581 10.1016/j.jns.2005.09.005 (Pubitemid 41814954)
-
(2006)
Journal of the Neurological Sciences
, vol.240
, Issue.1-2
, pp. 59-64
-
-
Verma, A.1
Berger, J.R.2
-
29
-
-
40349102131
-
Prevalence of SOD1 mutations in the Italian ALS population
-
DOI 10.1212/01.wnl.0000299187.90432.3f, PII 0000611420080212000008
-
Chiò A., Traynor B. J., Lombardo F., Fimognari M., Calvo A., Ghiglione P., Mutani R., Restagno G., Prevalence of SOD1 mutations in the Italian ALS population. Neurology 2008 70 7 533 537 2-s2.0-40349102131 10.1212/01.wnl.0000299187.90432.3f (Pubitemid 351653378)
-
(2008)
Neurology
, vol.70
, Issue.7
, pp. 533-537
-
-
Chio, A.1
Traynor, B.J.2
Lombardo, F.3
Fimognari, M.4
Calvo, A.5
Ghiglione, P.6
Mutani, R.7
Restagno, G.8
-
30
-
-
77949760219
-
Mutations of FUS gene in sporadic amyotrophic lateral sclerosis
-
2-s2.0-77949760219 10.1136/jmg.2009.071027
-
Corrado L., Del Bo R., Castellotti B., Ratti A., Cereda C., Penco S., Sorarù G., Carlomagno Y., Ghezzi S., Pensato V., Colombrita C., Gagliardi S., Cozzi L., Orsetti V., Mancuso M., Siciliano G., Mazzini L., Comi G. P., Gellera C., Ceroni M., D'Alfonso S., Silani V., Mutations of FUS gene in sporadic amyotrophic lateral sclerosis. Journal of Medical Genetics 2010 47 3 190 194 2-s2.0-77949760219 10.1136/jmg.2009.071027
-
(2010)
Journal of Medical Genetics
, vol.47
, Issue.3
, pp. 190-194
-
-
Corrado, L.1
Del Bo, R.2
Castellotti, B.3
Ratti, A.4
Cereda, C.5
Penco, S.6
Sorarù, G.7
Carlomagno, Y.8
Ghezzi, S.9
Pensato, V.10
Colombrita, C.11
Gagliardi, S.12
Cozzi, L.13
Orsetti, V.14
Mancuso, M.15
Siciliano, G.16
Mazzini, L.17
Comi, G.P.18
Gellera, C.19
Ceroni, M.20
D'Alfonso, S.21
Silani, V.22
more..
-
31
-
-
41149180753
-
TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis
-
DOI 10.1126/science.1154584
-
Sreedharan J., Blair I. P., Tripathi V. B., Hu X., Vance C., Rogelj B., Ackerley S., Durnall J. C., Williams K. L., Buratti E., Baralle F., De Belleroche J., Mitchell J. D., Leigh P. N., Al-Chalabi A., Miller C. C., Nicholson G., Shaw C. E., TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis. Science 2008 319 5870 1668 1672 2-s2.0-41149180753 10.1126/science.1154584 (Pubitemid 351432505)
-
(2008)
Science
, vol.319
, Issue.5870
, pp. 1668-1672
-
-
Sreedharan, J.1
Blair, I.P.2
Tripathi, V.B.3
Hu, X.4
Vance, C.5
Rogelj, B.6
Ackerley, S.7
Durnall, J.C.8
Williams, K.L.9
Buratti, E.10
Baralle, F.11
De Belleroche, J.12
Mitchell, J.D.13
Leigh, P.N.14
Al-Chalabi, A.15
Miller, C.C.16
Nicholson, G.17
Shaw, C.E.18
-
32
-
-
84869500227
-
Trauma and amyotrophic lateral sclerosis: A case-control study from a population-based registry
-
10.1111/j.1468-1331.2012.03723.x
-
Pupillo E., Messina P., Logroscino G., Zoccolella S., Chio A., Calvo A., Corbo M., Lunetta C., Micheli A., Millul A., Vitelli E., Beghi E., Consortium E., Trauma and amyotrophic lateral sclerosis: a case-control study from a population-based registry. European Journal of Neurology 2012 19 12 1509 1517 10.1111/j.1468-1331.2012.03723.x
-
(2012)
European Journal of Neurology
, vol.19
, Issue.12
, pp. 1509-1517
-
-
Pupillo, E.1
Messina, P.2
Logroscino, G.3
Zoccolella, S.4
Chio, A.5
Calvo, A.6
Corbo, M.7
Lunetta, C.8
Micheli, A.9
Millul, A.10
Vitelli, E.11
Beghi, E.12
Consortium, E.13
-
33
-
-
0142219821
-
The sinister side of Italian soccer
-
DOI 10.1016/S1474-4422(03)00579-9
-
Beretta S., Carrì M. T., Beghi E., Chiò A., Ferrarese C., The sinister side of Italian soccer. Lancet Neurology 2003 2 11 656 657 2-s2.0-0142219821 10.1016/S1474-4422(03)00579-9 (Pubitemid 37311316)
-
(2003)
Lancet Neurology
, vol.2
, Issue.11
, pp. 656-657
-
-
Beretta, S.1
Carri, M.T.2
Beghi, E.3
Chio, A.4
Ferrarese, C.5
-
34
-
-
84858000667
-
Cardiovascular fitness as a risk factor for amyotrophic lateral sclerosis: Indirect evidence from record linkage study
-
10.1136/jnnp-2011-301161
-
Turner M. R., Wotton C., Talbot K., Goldacre M. J., Cardiovascular fitness as a risk factor for amyotrophic lateral sclerosis: indirect evidence from record linkage study. Journal of Neurology, Neurosurgery & Psychiatry 2012 83 395 398 10.1136/jnnp-2011-301161
-
(2012)
Journal of Neurology, Neurosurgery & Psychiatry
, vol.83
, pp. 395-398
-
-
Turner, M.R.1
Wotton, C.2
Talbot, K.3
Goldacre, M.J.4
-
35
-
-
70350075024
-
Genetics of motor neuron disorders: New insights into pathogenic mechanisms
-
2-s2.0-70350075024 10.1038/nrg2680
-
Dion P. A., Daoud H., Rouleau G. A., Genetics of motor neuron disorders: new insights into pathogenic mechanisms. Nature Reviews Genetics 2009 10 11 769 782 2-s2.0-70350075024 10.1038/nrg2680
-
(2009)
Nature Reviews Genetics
, vol.10
, Issue.11
, pp. 769-782
-
-
Dion, P.A.1
Daoud, H.2
Rouleau, G.A.3
-
36
-
-
33750716074
-
TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
DOI 10.1016/j.bbrc.2006.10.093, PII S0006291X06023187
-
Arai T., Hasegawa M., Akiyama H., Ikeda K., Nonaka T., Mori H., Mann D., Tsuchiya K., Yoshida M., Hashizume Y., Oda T., TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Biochemical and Biophysical Research Communications 2006 351 3 602 611 2-s2.0-33750716074 10.1016/j.bbrc.2006.10.093 (Pubitemid 44708852)
-
(2006)
Biochemical and Biophysical Research Communications
, vol.351
, Issue.3
, pp. 602-611
-
-
Arai, T.1
Hasegawa, M.2
Akiyama, H.3
Ikeda, K.4
Nonaka, T.5
Mori, H.6
Mann, D.7
Tsuchiya, K.8
Yoshida, M.9
Hashizume, Y.10
Oda, T.11
-
37
-
-
33749632259
-
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
DOI 10.1126/science.1134108
-
Neumann M., Sampathu D. M., Kwong L. K., Truax A. C., Micsenyi M. C., Chou T. T., Bruce J., Schuck T., Grossman M., Clark C. M., McCluskey L. F., Miller B. L., Masliah E., Mackenzie I. R., Feldman H., Feiden W., Kretzschmar H. A., Trojanowski J. Q., Lee V. M. Y., Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science 2006 314 5796 130 133 2-s2.0-33749632259 10.1126/science.1134108 (Pubitemid 44547757)
-
(2006)
Science
, vol.314
, Issue.5796
, pp. 130-133
-
-
Neumann, M.1
Sampathu, D.M.2
Kwong, L.K.3
Truax, A.C.4
Micsenyi, M.C.5
Chou, T.T.6
Bruce, J.7
Schuck, T.8
Grossman, M.9
Clark, C.M.10
McCluskey, L.F.11
Miller, B.L.12
Masliah, E.13
Mackenzie, I.R.14
Feldman, H.15
Feiden, W.16
Kretzschmar, H.A.17
Trojanowski, J.Q.18
Lee, V.M.-Y.19
-
38
-
-
61349162349
-
Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6
-
2-s2.0-61349162349 10.1126/science.1165942
-
Vance C., Rogelj B., Hortobágyi T., De Vos K. J., Nishimura A. L., Sreedharan J., Hu X., Smith B., Ruddy D., Wright P., Ganesalingam J., Williams K. L., Tripathi V., Al-Saraj S., Al-Chalabi A., Leigh P. N., Blair I. P., Nicholson G., De Belleroche J., Gallo J. M., Miller C. C., Shaw C. E., Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6. Science 2009 323 5918 1208 1211 2-s2.0-61349162349 10.1126/science. 1165942
-
(2009)
Science
, vol.323
, Issue.5918
, pp. 1208-1211
-
-
Vance, C.1
Rogelj, B.2
Hortobágyi, T.3
De Vos, K.J.4
Nishimura, A.L.5
Sreedharan, J.6
Hu, X.7
Smith, B.8
Ruddy, D.9
Wright, P.10
Ganesalingam, J.11
Williams, K.L.12
Tripathi, V.13
Al-Saraj, S.14
Al-Chalabi, A.15
Leigh, P.N.16
Blair, I.P.17
Nicholson, G.18
De Belleroche, J.19
Gallo, J.M.20
Miller, C.C.21
Shaw, C.E.22
more..
-
39
-
-
0034785509
-
The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis
-
DOI 10.1038/ng1001-160
-
Yang Y., Hentati A., Deng H. X., Dabbagh O., Sasaki T., Hirano M., Hung W. Y., Ouahchi K., Yan J., Azim A. C., Cole N., Gascon G., Yagmour A., Ben-Hamida M., Pericak-Vance M., Hentati F., Siddique T., The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis. Nature Genetics 2001 29 160 165 10.1038/ng1001-160 (Pubitemid 32952652)
-
(2001)
Nature Genetics
, vol.29
, Issue.2
, pp. 160-165
-
-
Yang, Y.1
Hentati, A.2
Deng, H.-X.3
Dabbagh, O.4
Sasaki, T.5
Hirano, M.6
Hung, W.-Y.7
Ouahchi, K.8
Yan, J.9
Azim, A.C.10
Cole, N.11
Gascon, G.12
Yagmour, A.13
Ben-Hamida, M.14
Pericak-Vance, M.15
Hentati, F.16
Siddique, T.17
-
40
-
-
6344257200
-
A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis
-
DOI 10.1086/425287
-
Nishimura A. L., Mitne-Neto M., Silva H. C. A., Richieri-Costa A., Middleton S., Cascio D., Kok F., Oliveira J. R. M., Gillingwater T., Webb J., Skehel P., Zatz M., A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis. American Journal of Human Genetics 2004 75 5 822 831 2-s2.0-6344257200 10.1086/425287 (Pubitemid 39390489)
-
(2004)
American Journal of Human Genetics
, vol.75
, Issue.5
, pp. 822-831
-
-
Nishimura, A.L.1
Mitne-Neto, M.2
Silva, H.C.A.3
Richieri-Costa, A.4
Middleton, S.5
Cascio, D.6
Kok, F.7
Oliveira, J.R.M.8
Gillingwater, T.9
Webb, J.10
Skehel, P.11
Zatz, M.12
-
41
-
-
61349156118
-
Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis
-
2-s2.0-61349156118 10.1126/science.1166066
-
Kwiatkowski T. J. Jr., Bosco D. A., LeClerc A. L., Tamrazian E., Vanderburg C. R., Russ C., Davis A., Gilchrist J., Kasarskis E. J., Munsat T., Valdmanis P., Rouleau G. A., Hosler B. A., Cortelli P., De Jong P. J., Yoshinaga Y., Haines J. L., Pericak-Vance M. A., Yan J., Ticozzi N., Siddique T., McKenna-Yasek D., Sapp P. C., Horvitz H. R., Landers J. E., Brown R. H., Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis. Science 2009 323 5918 1205 1208 2-s2.0-61349156118 10.1126/science.1166066
-
(2009)
Science
, vol.323
, Issue.5918
, pp. 1205-1208
-
-
Kwiatkowski Jr., T.J.1
Bosco, D.A.2
Leclerc, A.L.3
Tamrazian, E.4
Vanderburg, C.R.5
Russ, C.6
Davis, A.7
Gilchrist, J.8
Kasarskis, E.J.9
Munsat, T.10
Valdmanis, P.11
Rouleau, G.A.12
Hosler, B.A.13
Cortelli, P.14
De Jong, P.J.15
Yoshinaga, Y.16
Haines, J.L.17
Pericak-Vance, M.A.18
Yan, J.19
Ticozzi, N.20
Siddique, T.21
McKenna-Yasek, D.22
Sapp, P.C.23
Horvitz, H.R.24
Landers, J.E.25
Brown, R.H.26
more..
-
42
-
-
77952419246
-
Mutations of optineurin in amyotrophic lateral sclerosis
-
2-s2.0-77952419246 10.1038/nature08971
-
Maruyama H., Morino H., Ito H., Izumi Y., Kato H., Watanabe Y., Kinoshita Y., Kamada M., Nodera H., Suzuki H., Komure O., Matsuura S., Kobatake K., Morimoto N., Abe K., Suzuki N., Aoki M., Kawata A., Hirai T., Kato T., Ogasawara K., Hirano A., Takumi T., Kusaka H., Hagiwara K., Kaji R., Kawakami H., Mutations of optineurin in amyotrophic lateral sclerosis. Nature 2010 465 7295 223 226 2-s2.0-77952419246 10.1038/nature08971
-
(2010)
Nature
, vol.465
, Issue.7295
, pp. 223-226
-
-
Maruyama, H.1
Morino, H.2
Ito, H.3
Izumi, Y.4
Kato, H.5
Watanabe, Y.6
Kinoshita, Y.7
Kamada, M.8
Nodera, H.9
Suzuki, H.10
Komure, O.11
Matsuura, S.12
Kobatake, K.13
Morimoto, N.14
Abe, K.15
Suzuki, N.16
Aoki, M.17
Kawata, A.18
Hirai, T.19
Kato, T.20
Ogasawara, K.21
Hirano, A.22
Takumi, T.23
Kusaka, H.24
Hagiwara, K.25
Kaji, R.26
Kawakami, H.27
more..
-
43
-
-
80052580969
-
Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia
-
10.1038/nature10353
-
Deng H. X., Chen W., Hong S. T., Boycott K. M., Gorrie G. H., Siddique N., Yang Y., Fecto F., Shi Y., Zhai H., Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia. Nature 2011 477 211 215 10.1038/nature10353
-
(2011)
Nature
, vol.477
, pp. 211-215
-
-
Deng, H.X.1
Chen, W.2
Hong, S.T.3
Boycott, K.M.4
Gorrie, G.H.5
Siddique, N.6
Yang, Y.7
Fecto, F.8
Shi, Y.9
Zhai, H.10
-
44
-
-
80054832080
-
Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS
-
10.1016/j.neuron.2011.09.011
-
DeJesus-Hernandez M., Mackenzie I. R., Boeve B. F., Boxer A. L., Baker M., Rutherford N. J., Nicholson A. M., Finch N. C. A., Flynn H., Adamson J., Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS. Neuron 2011 72 2 245 256 10.1016/j.neuron. 2011.09.011
-
(2011)
Neuron
, vol.72
, Issue.2
, pp. 245-256
-
-
Dejesus-Hernandez, M.1
MacKenzie, I.R.2
Boeve, B.F.3
Boxer, A.L.4
Baker, M.5
Rutherford, N.J.6
Nicholson, A.M.7
Finch, N.C.A.8
Flynn, H.9
Adamson, J.10
-
45
-
-
3943102116
-
Unraveling the mechanisms involved in motor neuron degeneration in ALS
-
DOI 10.1146/annurev.neuro.27.070203.144244
-
Bruijn L. I., Miller T. M., Cleveland D. W., Unraveling the mechanisms involved in motor neuron degeneration in ALS. Annual Review of Neuroscience 2004 27 723 749 2-s2.0-3943102116 10.1146/annurev.neuro.27.070203.144244 (Pubitemid 39050419)
-
(2004)
Annual Review of Neuroscience
, vol.27
, pp. 723-749
-
-
Bruijn, L.I.1
Miller, T.M.2
Cleveland, D.W.3
-
46
-
-
0030777650
-
Aggregation of mutant Cu/Zn superoxide dismutase proteins in a culture model of ALS
-
Durham H. D., Roy J., Dong L., Figlewicz D. A., Aggregation of mutant Cu/Zn superoxide dismutase proteins in a culture model of ALS. Journal of Neuropathology and Experimental Neurology 1997 56 5 523 530 2-s2.0-0030777650 (Pubitemid 27463093)
-
(1997)
Journal of Neuropathology and Experimental Neurology
, vol.56
, Issue.5
, pp. 523-530
-
-
Durham, H.D.1
Roy, J.2
Dong, L.3
Figlewicz, D.A.4
-
47
-
-
0035664213
-
Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues
-
DOI 10.1006/nbdi.2001.0443
-
Watanabe M., Dykes-Hoberg M., Cizewski Culotta V., Price D. L., Wong P. C., Rothstein J. D., Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues. Neurobiology of Disease 2001 8 6 933 941 2-s2.0-0035664213 10.1006/nbdi.2001. 0443 (Pubitemid 34017087)
-
(2001)
Neurobiology of Disease
, vol.8
, Issue.6
, pp. 933-941
-
-
Watanabe, M.1
Dykes-Hoberg, M.2
Cizewski Culotta, V.3
Price, D.L.4
Wong, P.C.5
Rothstein, J.D.6
-
48
-
-
0037264120
-
Unfolding the role of protein misfolding in neurodegenerative diseases
-
DOI 10.1038/nrn1007
-
Soto C., Unfolding the role of protein misfolding in neurodegenerative diseases. Nature Reviews Neuroscience 2003 4 1 49 60 2-s2.0-0037264120 10.1038/nrn1007 (Pubitemid 37271088)
-
(2003)
Nature Reviews Neuroscience
, vol.4
, Issue.1
, pp. 49-60
-
-
Soto, C.1
-
49
-
-
33645108336
-
Mapping superoxide dismutase 1 domains of non-native interaction: Roles of intra- and intermolecular disulfide bonding in aggregation
-
2-s2.0-33645108336 10.1111/j.1471-4159.2005.03642.x
-
Wang J., Xu G., Borchelt D. R., Mapping superoxide dismutase 1 domains of non-native interaction: roles of intra- and intermolecular disulfide bonding in aggregation. Journal of Neurochemistry 2006 96 5 1277 1288 2-s2.0-33645108336 10.1111/j.1471-4159.2005.03642.x
-
(2006)
Journal of Neurochemistry
, vol.96
, Issue.5
, pp. 1277-1288
-
-
Wang, J.1
Xu, G.2
Borchelt, D.R.3
-
50
-
-
67749133873
-
TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity
-
10.1074/jbc.M109.010264
-
Johnson B. S., Snead D., Lee J. J., McCaffery J. M., Shorter J., Gitler A. D., TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity. Journal of Biological Chemistry 2009 284 20329 20339 10.1074/jbc.M109.010264
-
(2009)
Journal of Biological Chemistry
, vol.284
, pp. 20329-20339
-
-
Johnson, B.S.1
Snead, D.2
Lee, J.J.3
McCaffery, J.M.4
Shorter, J.5
Gitler, A.D.6
-
51
-
-
61349162349
-
Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6
-
2-s2.0-61349162349 10.1126/science.1165942
-
Vance C., Rogelj B., Hortobágyi T., De Vos K. J., Nishimura A. L., Sreedharan J., Hu X., Smith B., Ruddy D., Wright P., Ganesalingam J., Williams K. L., Tripathi V., Al-Saraj S., Al-Chalabi A., Leigh P. N., Blair I. P., Nicholson G., De Belleroche J., Gallo J. M., Miller C. C., Shaw C. E., Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6. Science 2009 323 5918 1208 1211 2-s2.0-61349162349 10.1126/science. 1165942
-
(2009)
Science
, vol.323
, Issue.5918
, pp. 1208-1211
-
-
Vance, C.1
Rogelj, B.2
Hortobágyi, T.3
De Vos, K.J.4
Nishimura, A.L.5
Sreedharan, J.6
Hu, X.7
Smith, B.8
Ruddy, D.9
Wright, P.10
Ganesalingam, J.11
Williams, K.L.12
Tripathi, V.13
Al-Saraj, S.14
Al-Chalabi, A.15
Leigh, P.N.16
Blair, I.P.17
Nicholson, G.18
De Belleroche, J.19
Gallo, J.M.20
Miller, C.C.21
Shaw, C.E.22
more..
-
52
-
-
33750716074
-
TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
DOI 10.1016/j.bbrc.2006.10.093, PII S0006291X06023187
-
Arai T., Hasegawa M., Akiyama H., Ikeda K., Nonaka T., Mori H., Mann D., Tsuchiya K., Yoshida M., Hashizume Y., Oda T., TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Biochemical and Biophysical Research Communications 2006 351 3 602 611 2-s2.0-33750716074 10.1016/j.bbrc.2006.10.093 (Pubitemid 44708852)
-
(2006)
Biochemical and Biophysical Research Communications
, vol.351
, Issue.3
, pp. 602-611
-
-
Arai, T.1
Hasegawa, M.2
Akiyama, H.3
Ikeda, K.4
Nonaka, T.5
Mori, H.6
Mann, D.7
Tsuchiya, K.8
Yoshida, M.9
Hashizume, Y.10
Oda, T.11
-
53
-
-
0029927679
-
Intense superoxide dismutase-1 immunoreactivity in intracytoplasmic hyaline inclusions of familial amyotrophic lateral sclerosis with posterior column involvement
-
Shibata N., Hirano A., Kobayashi M., Siddique T., Deng H. X., Hung W. Y., Kato T., Asayama K., Intense superoxide dismutase-1 immunoreactivity in intracytoplasmic hyaline inclusions of familial amyotrophic lateral sclerosis with posterior column involvement. Journal of Neuropathology and Experimental Neurology 1996 55 4 481 490 2-s2.0-0029927679 (Pubitemid 26112102)
-
(1996)
Journal of Neuropathology and Experimental Neurology
, vol.55
, Issue.4
, pp. 481-490
-
-
Shibata, N.1
Hirano, A.2
Kobayashi, M.3
Siddique, T.4
Deng, H.-X.5
Hung, W.-Y.6
Kato, T.7
Asayama, K.8
-
54
-
-
22244479388
-
Copper-zinc superoxide dismutase and amyotrophic lateral sclerosis
-
DOI 10.1146/annurev.biochem.72.121801.161647
-
Valentine J. S., Doucette P. A., Potter S. Z., Copper-zinc superoxide dismutase and amyotrophic lateral sclerosis. Annual Review of Biochemistry 2005 74 563 593 2-s2.0-22244479388 10.1146/annurev.biochem.72.121801.161647 (Pubitemid 40995518)
-
(2005)
Annual Review of Biochemistry
, vol.74
, pp. 563-593
-
-
Valentine, J.S.1
Doucette, P.A.2
Potter, S.Z.3
-
55
-
-
9144261759
-
The unusually stable quaternary structure of human Cu,Zn-superoxide dismutase 1 is controlled by both metal occupancy and disulfide status
-
DOI 10.1074/jbc.M406021200
-
Arnesano F., Banci L., Bertini I., Martinelli M., Furukawa Y., O'Halloran T. V., The unusually stable quaternary structure of human Cu,Zn-superoxide dismutase 1 is controlled by both metal occupancy and disulfide status. Journal of Biological Chemistry 2004 279 46 47998 48003 2-s2.0-9144261759 10.1074/jbc.M406021200 (Pubitemid 39540952)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.46
, pp. 47998-48003
-
-
Arnesano, F.1
Banci, L.2
Bertini, I.3
Martinelli, M.4
Furukawa, Y.5
O'Halloran, T.V.6
-
56
-
-
77951765013
-
Disulfide-Reduced ALS Variants of Cu, Zn Superoxide Dismutase Exhibit Increased Populations of Unfolded Species
-
2-s2.0-77951765013 10.1016/j.jmb.2010.02.034
-
Kayatekin C., Zitzewitz J. A., Matthews C. R., Disulfide-Reduced ALS Variants of Cu, Zn Superoxide Dismutase Exhibit Increased Populations of Unfolded Species. Journal of Molecular Biology 2010 398 2 320 331 2-s2.0-77951765013 10.1016/j.jmb.2010.02.034
-
(2010)
Journal of Molecular Biology
, vol.398
, Issue.2
, pp. 320-331
-
-
Kayatekin, C.1
Zitzewitz, J.A.2
Matthews, C.R.3
-
57
-
-
77956303784
-
Metal-free ALS variants of dimeric human Cu,Zn-superoxide dismutase have enhanced populations of monomeric species
-
2-s2.0-77956303784 10.1371/journal.pone.0010064 e10064
-
Svensson A. E., Bilsel O., Kayatekin C., Adefusika J. A., Zitzewitz J. A., Robert Matthews C., Metal-free ALS variants of dimeric human Cu,Zn-superoxide dismutase have enhanced populations of monomeric species. PLoS ONE 2010 5 4 2-s2.0-77956303784 10.1371/journal.pone.0010064 e10064
-
(2010)
PLoS ONE
, vol.5
, Issue.4
-
-
Svensson, A.E.1
Bilsel, O.2
Kayatekin, C.3
Adefusika, J.A.4
Zitzewitz, J.A.5
Robert Matthews, C.6
-
58
-
-
84865654196
-
Amyotrophic lateral sclerosis: New insights into underlying molecular mechanisms and opportunities for therapeutic intervention
-
10.1089/ars.2011.4328
-
Cozzolino M., Pesaresi M. G., Gerbino V., Grosskreutz J., Carr? M. T., Amyotrophic lateral sclerosis: new insights into underlying molecular mechanisms and opportunities for therapeutic intervention. Antioxidants & Redox Signaling 2012 17 9 1277 1330 10.1089/ars.2011.4328
-
(2012)
Antioxidants & Redox Signaling
, vol.17
, Issue.9
, pp. 1277-1330
-
-
Cozzolino, M.1
Pesaresi, M.G.2
Gerbino, V.3
Grosskreutz, J.4
Carr, M.T.5
-
59
-
-
0037081113
-
Glutamate levels in cerebrospinal fluid in amyotrophic lateral sclerosis: A reappraisal using a new HPLC method with coulometric detection in a large cohort of patients
-
DOI 10.1016/S0022-510X(01)00661-X, PII S0022510X0100661X
-
Spreux-Varoquaux O., Bensimon G., Lacomblez L., Salachas F., Pradat P. F., Le Forestier N., Marouan A., Dib M., Meininger V., Glutamate levels in cerebrospinal fluid in amyotrophic lateral sclerosis: a reappraisal using a new HPLC method with coulometric detection in a large cohort of patients. Journal of the Neurological Sciences 2002 193 2 73 78 2-s2.0-0037081113 10.1016/S0022-510X(01)00661-X (Pubitemid 34098937)
-
(2002)
Journal of the Neurological Sciences
, vol.193
, Issue.2
, pp. 73-78
-
-
Spreux-Varoquaux, O.1
Bensimon, G.2
Lacomblez, L.3
Salachas, F.4
Pradat, P.F.5
Le Forestier, N.6
Marouan, A.7
Dib, M.8
Meininger, V.9
-
60
-
-
0037382240
-
Mutant dynactin in motor neuron disease
-
DOI 10.1038/ng1123
-
Puls I., Jonnakuty C., LaMonte B. H., Holzbaur E. L. F., Tokito M., Mann E., Floeter M. K., Bidus K., Drayna D., Oh S. J., Brown R. H., Ludlow C. L., Fischbeck K. H., Mutant dynactin in motor neuron disease. Nature Genetics 2003 33 4 455 456 2-s2.0-0037382240 10.1038/ng1123 (Pubitemid 36390002)
-
(2003)
Nature Genetics
, vol.33
, Issue.4
, pp. 455-456
-
-
Puls, I.1
Jonnakuty, C.2
LaMonte, B.H.3
Holzbaur, E.L.F.4
Tokito, M.5
Mann, E.6
Floeter, M.K.7
Bidus, K.8
Drayna, D.9
Oh, S.J.10
Brown Jr., R.H.11
Ludlow, C.L.12
Fischbeck, K.H.13
-
61
-
-
0029004898
-
Defective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosis
-
2-s2.0-0029004898
-
Collard J. F., Cote F., Julien J. P., Defective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosis. Nature 1995 375 6526 61 64 2-s2.0-0029004898
-
(1995)
Nature
, vol.375
, Issue.6526
, pp. 61-64
-
-
Collard, J.F.1
Cote, F.2
Julien, J.P.3
-
62
-
-
0032079517
-
Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1
-
Kong J., Xu Z., Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1. Journal of Neuroscience 1998 18 9 3241 3250 2-s2.0-0032079517 (Pubitemid 28186017)
-
(1998)
Journal of Neuroscience
, vol.18
, Issue.9
, pp. 3241-3250
-
-
Kong, J.1
Xu, Z.2
-
63
-
-
0032539791
-
Impairment of mitochondrial function in skeletal muscle of patients with amyotrophic lateral sclerosis
-
DOI 10.1016/S0022-510X(98)00008-2, PII S0022510X98000082
-
Wiedemann F. R., Winkler K., Kuznetsov A. V., Bartels C., Vielhaber S., Feistner H., Kunz W. S., Impairment of mitochondrial function in skeletal muscle of patients with amyotrophic lateral sclerosis. Journal of the Neurological Sciences 1998 156 1 65 72 2-s2.0-0032539791 10.1016/S0022-510X(98)00008-2 (Pubitemid 28141041)
-
(1998)
Journal of the Neurological Sciences
, vol.156
, Issue.1
, pp. 65-72
-
-
Wiedemann, F.R.1
Winkler, K.2
Kuznetsov, A.V.3
Bartels, C.4
Vielhaber, S.5
Feistner, H.6
Kunz, W.S.7
-
64
-
-
0021167918
-
Fine structural observations of neurofilamentous changes in amyotrophic lateral sclerosis
-
Hirano A., Donnenfeld H., Sasaki S., Nakano I., Fine structural observations of neurofilamentous changes in amyotrophic lateral sclerosis. Journal of Neuropathology and Experimental Neurology 1984 43 5 461 470 2-s2.0-0021167918 (Pubitemid 14027581)
-
(1984)
Journal of Neuropathology and Experimental Neurology
, vol.43
, Issue.5
, pp. 461-470
-
-
Hirano, A.1
Donnenfeld, H.2
Sasaki, S.3
Nakano, I.4
-
65
-
-
0346749654
-
Protein aggregation in motor neurone disorders
-
DOI 10.1046/j.0305-1846.2003.00518.x
-
Wood J. D., Beaujeux T. P., Shaw P. J., Protein aggregation in motor neurone disorders. Neuropathology and Applied Neurobiology 2003 29 6 529 545 2-s2.0-0346749654 10.1046/j.0305-1846.2003.00518.x (Pubitemid 37548348)
-
(2003)
Neuropathology and Applied Neurobiology
, vol.29
, Issue.6
, pp. 529-545
-
-
Wood, J.D.1
Beaujeux, T.P.2
Shaw, P.J.3
-
66
-
-
43649100018
-
Endoplasmic reticulum stress and induction of the unfolded protein response in human sporadic amyotrophic lateral sclerosis
-
2-s2.0-43649100018 10.1016/j.nbd.2008.02.009
-
Atkin J. D., Farg M. A., Walker A. K., McLean C., Tomas D., Horne M. K., Endoplasmic reticulum stress and induction of the unfolded protein response in human sporadic amyotrophic lateral sclerosis. Neurobiology of Disease 2008 30 3 400 407 2-s2.0-43649100018 10.1016/j.nbd.2008.02.009
-
(2008)
Neurobiology of Disease
, vol.30
, Issue.3
, pp. 400-407
-
-
Atkin, J.D.1
Farg, M.A.2
Walker, A.K.3
McLean, C.4
Tomas, D.5
Horne, M.K.6
-
67
-
-
83455243339
-
Autophagy dysregulation in amyotrophic lateral sclerosis
-
10.1111/j.1750-3639.2011.00546.x
-
Chen S., Zhang X., Song L., Le W., Autophagy dysregulation in amyotrophic lateral sclerosis. Brain Pathology 2012 22 1 110 116 10.1111/j.1750-3639.2011. 00546.x
-
(2012)
Brain Pathology
, vol.22
, Issue.1
, pp. 110-116
-
-
Chen, S.1
Zhang, X.2
Song, L.3
Le, W.4
-
68
-
-
0036789845
-
Evidence that accumulation of ceramides and cholesterol esters mediates oxidative stress-induced death of motor neurons in amyotrophic lateral sclerosis
-
2-s2.0-0036789845 10.1002/ana.10312
-
Cutler R. G., Pedersen W. A., Camandola S., Rothstein J. D., Mattson M. P., Evidence that accumulation of ceramides and cholesterol esters mediates oxidative stress-induced death of motor neurons in amyotrophic lateral sclerosis. Annals of Neurology 2002 52 4 448 457 2-s2.0-0036789845 10.1002/ana.10312
-
(2002)
Annals of Neurology
, vol.52
, Issue.4
, pp. 448-457
-
-
Cutler, R.G.1
Pedersen, W.A.2
Camandola, S.3
Rothstein, J.D.4
Mattson, M.P.5
-
69
-
-
0030813067
-
Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis
-
Ferrante R. J., Browne S. E., Shinobu L. A., Bowling A. C., Baik M. J., MacGarvey U., Kowall N. W., Brown R. H., Beal M. F., Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis. Journal of Neurochemistry 1997 69 5 2064 2074 2-s2.0-0030813067 (Pubitemid 27452754)
-
(1997)
Journal of Neurochemistry
, vol.69
, Issue.5
, pp. 2064-2074
-
-
Ferrante, R.J.1
Browne, S.E.2
Shinobu, L.A.3
Bowling, A.C.4
Baik, M.J.5
MacGarvey, U.6
Kowall, N.W.7
Brown Jr., R.H.8
Beal, M.F.9
-
70
-
-
0033807443
-
Increased oxidative damage to DNA in ALS patients
-
2-s2.0-0033807443 10.1016/S0891-5849(00)00349-X
-
Bogdanov M., Brown R. H., Matson W., Smart R., Hayden D., O'Donnell H., Flint Beal M., Cudkowicz M., Increased oxidative damage to DNA in ALS patients. Free Radical Biology and Medicine 2000 29 7 652 658 2-s2.0-0033807443 10.1016/S0891-5849(00)00349-X
-
(2000)
Free Radical Biology and Medicine
, vol.29
, Issue.7
, pp. 652-658
-
-
Bogdanov, M.1
Brown, R.H.2
Matson, W.3
Smart, R.4
Hayden, D.5
O'Donnell, H.6
Flint Beal, M.7
Cudkowicz, M.8
-
71
-
-
0031821531
-
Lipid hydroperoxide generation, turnover, and effector action in biological systems
-
Girotti A. W., Lipid hydroperoxide generation, turnover, and effector action in biological systems. Journal of Lipid Research 1998 39 8 1529 1542 2-s2.0-0031821531 (Pubitemid 28377917)
-
(1998)
Journal of Lipid Research
, vol.39
, Issue.8
, pp. 1529-1542
-
-
Girotti, A.W.1
-
72
-
-
0029082389
-
Oxidative damage to protein in sporadic motor neuron disease spinal cord
-
2-s2.0-0029082389 10.1002/ana.410380424
-
Shaw P. J., Ince P. G., Falkous G., Mantle D., Oxidative damage to protein in sporadic motor neuron disease spinal cord. Annals of Neurology 1995 38 4 691 695 2-s2.0-0029082389 10.1002/ana.410380424
-
(1995)
Annals of Neurology
, vol.38
, Issue.4
, pp. 691-695
-
-
Shaw, P.J.1
Ince, P.G.2
Falkous, G.3
Mantle, D.4
-
73
-
-
0032764587
-
The roles of free radicals in amyotrophic lateral sclerosis: Reactive oxygen species and elevated oxidation of protein, DNA, and membrane phospholipids
-
2-s2.0-0032764587
-
Liu D., Wen J., Liu J., Li L., The roles of free radicals in amyotrophic lateral sclerosis: reactive oxygen species and elevated oxidation of protein, DNA, and membrane phospholipids. FASEB Journal 1999 13 15 2318 2328 2-s2.0-0032764587
-
(1999)
FASEB Journal
, vol.13
, Issue.15
, pp. 2318-2328
-
-
Liu, D.1
Wen, J.2
Liu, J.3
Li, L.4
-
74
-
-
66749102059
-
Redox modifier genes and pathways in amyotrophic lateral sclerosis
-
2-s2.0-66749102059 10.1089/ars.2008.2414
-
Carter B. J., Anklesaria P., Choi S., Engelhardt J. F., Redox modifier genes and pathways in amyotrophic lateral sclerosis. Antioxidants and Redox Signaling 2009 11 7 1569 1586 2-s2.0-66749102059 10.1089/ars.2008.2414
-
(2009)
Antioxidants and Redox Signaling
, vol.11
, Issue.7
, pp. 1569-1586
-
-
Carter, B.J.1
Anklesaria, P.2
Choi, S.3
Engelhardt, J.F.4
-
75
-
-
22544448129
-
Redox proteomics analysis of oxidatively modified proteins in G93A-SOD1 transgenic mice - A model of familial amyotrophic lateral sclerosis
-
DOI 10.1016/j.freeradbiomed.2005.03.030, PII S0891584905001875
-
Poon H. F., Hensley K., Thongboonkerd V., Merchant M. L., Lynn B. C., Pierce W. M., Klein J. B., Calabrese V., Butterfield D. A., Redox proteomics analysis of oxidatively modified proteins in G93A-SOD1 transgenic mice-a model of familial amyotrophic lateral sclerosis. Free Radical Biology and Medicine 2005 39 4 453 462 2-s2.0-22544448129 10.1016/j.freeradbiomed.2005.03.030 (Pubitemid 41021644)
-
(2005)
Free Radical Biology and Medicine
, vol.39
, Issue.4
, pp. 453-462
-
-
Poon, H.F.1
Hensley, K.2
Thongboonkerd, V.3
Merchant, M.L.4
Lynn, B.C.5
Pierce, W.M.6
Klein, J.B.7
Calabrese, V.8
Butterfield, D.A.9
-
76
-
-
0036829062
-
Antioxidant and prooxidant mechanisms in the regulation of redox(y)-sensitive transcription factors
-
DOI 10.1016/S0898-6568(02)00053-0, PII S0898656802000530
-
Haddad J. J., Antioxidant and prooxidant mechanisms in the regulation of redox(y)-sensitive transcription factors. Cellular Signalling 2002 14 11 879 897 2-s2.0-0036829062 10.1016/S0898-6568(02)00053-0 (Pubitemid 35247561)
-
(2002)
Cellular Signalling
, vol.14
, Issue.11
, pp. 879-897
-
-
Haddad, J.J.1
-
77
-
-
0036511547
-
Reactive oxygen species and regulation of gene expression
-
2-s2.0-0036511547 10.1023/A:1014819832003
-
Turpaev K. T., Reactive oxygen species and regulation of gene expression. Biochemistry 2002 67 3 281 292 2-s2.0-0036511547 10.1023/A:1014819832003
-
(2002)
Biochemistry
, vol.67
, Issue.3
, pp. 281-292
-
-
Turpaev, K.T.1
-
78
-
-
79960213740
-
Bcl2-A1 interacts with pro-caspase-3: Implications for amyotrophic lateral sclerosis
-
2-s2.0-79960213740 10.1016/j.nbd.2011.05.013
-
Iaccarino C., Mura M. E., Esposito S., Carta F., Sanna G., Turrini F., Carrì M. T., Crosio C., Bcl2-A1 interacts with pro-caspase-3: implications for amyotrophic lateral sclerosis. Neurobiology of Disease 2011 43 3 642 650 2-s2.0-79960213740 10.1016/j.nbd.2011.05.013
-
(2011)
Neurobiology of Disease
, vol.43
, Issue.3
, pp. 642-650
-
-
Iaccarino, C.1
Mura, M.E.2
Esposito, S.3
Carta, F.4
Sanna, G.5
Turrini, F.6
Carrì, M.T.7
Crosio, C.8
-
79
-
-
78650721472
-
Deregulation of the hypoxia inducible factor-1 α pathway in monocytes from sporadic amyotrophic lateral sclerosis patients
-
10.1016/j.neuroscience.2010.10.040
-
Moreau C., Gosset P., Kluza J., Brunaud-Danel V., Lassalle P., Marchetti P., Defebvre L., Destée A., Devos D., Deregulation of the hypoxia inducible factor-1 α pathway in monocytes from sporadic amyotrophic lateral sclerosis patients. Neuroscience 2011 172 110 117 10.1016/j. neuroscience.2010.10.040
-
(2011)
Neuroscience
, vol.172
, pp. 110-117
-
-
Moreau, C.1
Gosset, P.2
Kluza, J.3
Brunaud-Danel, V.4
Lassalle, P.5
Marchetti, P.6
Defebvre, L.7
Destée, A.8
Devos, D.9
-
80
-
-
66049156169
-
Role of mutant SOD1 disulfide oxidation and aggregation in the pathogenesis of familial ALS
-
2-s2.0-66049156169 10.1073/pnas.0902505106
-
Karch C. M., Prudencio M., Winkler D. D., Hart P. J., Borchelt D. R., Role of mutant SOD1 disulfide oxidation and aggregation in the pathogenesis of familial ALS. Proceedings of the National Academy of Sciences of the United States of America 2009 106 19 7774 7779 2-s2.0-66049156169 10.1073/pnas. 0902505106
-
(2009)
Proceedings of the National Academy of Sciences of the United States of America
, vol.106
, Issue.19
, pp. 7774-7779
-
-
Karch, C.M.1
Prudencio, M.2
Winkler, D.D.3
Hart, P.J.4
Borchelt, D.R.5
-
81
-
-
44849139852
-
Biological effects of CCS in the absence of SOD1 enzyme activation: Implications for disease in a mouse model for ALS
-
DOI 10.1093/hmg/ddn063
-
Proescher J. B., Son M., Elliott J. L., Culotta V. C., Biological effects of CCS in the absence of SOD1 enzyme activation: implications for disease in a mouse model for ALS. Human Molecular Genetics 2008 17 12 1728 1737 2-s2.0-44849139852 10.1093/hmg/ddn063 (Pubitemid 351791499)
-
(2008)
Human Molecular Genetics
, vol.17
, Issue.12
, pp. 1728-1737
-
-
Proescher, J.B.1
Son, M.2
Elliott, J.L.3
Culotta, V.C.4
-
82
-
-
0014691242
-
Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein)
-
2-s2.0-0014691242
-
McCord J. M., Fridovich I., Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein). Journal of Biological Chemistry 1969 244 22 6049 6055 2-s2.0-0014691242
-
(1969)
Journal of Biological Chemistry
, vol.244
, Issue.22
, pp. 6049-6055
-
-
McCord, J.M.1
Fridovich, I.2
-
83
-
-
34447329567
-
Mutation of SOD1 in ALS: A gain of a loss of function
-
DOI 10.1093/hmg/ddm110
-
Sau D., De Biasi S., Vitellaro-Zuccarello L., Riso P., Guarnieri S., Porrini M., Simeoni S., Crippa V., Onesto E., Palazzolo I., Rusmini P., Bolzoni E., Bendotti C., Poletti A., Mutation of SOD1 in ALS: a gain of a loss of function. Human Molecular Genetics 2007 16 13 1604 1618 2-s2.0-34447329567 10.1093/hmg/ddm110 (Pubitemid 47050674)
-
(2007)
Human Molecular Genetics
, vol.16
, Issue.13
, pp. 1604-1618
-
-
Sau, D.1
De Biasi, S.2
Vitellaro-Zuccarello, L.3
Riso, P.4
Guarnieri, S.5
Porrini, M.6
Simeoni, S.7
Crippa, V.8
Onesto, E.9
Palazzolo, I.10
Rusmini, P.11
Bolzoni, E.12
Bendotti, C.13
Poletti, A.14
-
84
-
-
0027293275
-
ALS, SOD and peroxynitrite [9]
-
DOI 10.1038/364584a0
-
Beckman J. S., Carson M., Smith C. D., Koppenol W. H., ALS, SOD and peroxynitrite. Nature 1993 364 6438 584 2-s2.0-0027293275 10.1038/364584a0 (Pubitemid 23274713)
-
(1993)
Nature
, vol.364
, Issue.6438
, pp. 584
-
-
Beckman, J.S.1
Carson, M.2
Smith, C.D.3
Koppenol, W.H.4
-
85
-
-
33845378793
-
Reaction of superoxide with nitric oxide to form peroxonitrite in alkaline aqueous solution
-
2-s2.0-33845378793
-
Blough N. V., Zafiriou O. C., Reaction of superoxide with nitric oxide to form peroxonitrite in alkaline aqueous solution. Inorganic Chemistry 1985 24 22 3502 3504 2-s2.0-33845378793
-
(1985)
Inorganic Chemistry
, vol.24
, Issue.22
, pp. 3502-3504
-
-
Blough, N.V.1
Zafiriou, O.C.2
-
86
-
-
0030851761
-
Increased 3-nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis
-
DOI 10.1002/ana.410420416
-
Beal M. F., Ferrante R. J., Browne S. E. Jr., Matthews R. T., Kowall N. W., Brown R. H., Increased 3-nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis. Annals of Neurology 1997 42 4 644 654 2-s2.0-0030851761 10.1002/ana.410420416 (Pubitemid 27439028)
-
(1997)
Annals of Neurology
, vol.42
, Issue.4
, pp. 644-654
-
-
Beal, M.F.1
Ferrante, R.J.2
Browne, S.E.3
Matthews, R.T.4
Kowall, N.W.5
Brown Jr., R.H.6
-
87
-
-
0033009113
-
Remarkable increase in cerebrospinal fluid 3-nitrotyrosine in patients with sporadic amyotrophic lateral sclerosis
-
DOI 10.1002/1531-8249(199 907)46:1<129::AID-ANA 21>3.0.CO;2-Y
-
Tohgi H., Abe T., Yamazaki K., Murata T., Ishizaki E., Isobe C., Remarkable increase in cerebrospinal fluid 3-nitrotyrosine in patients with sporadic amyotrophic lateral sclerosis. Annals of Neurology 1999 46 129 131 10.1002/1531-8249(199907)46:1<129::AID-ANA21>3.0.CO;2-Y (Pubitemid 29314394)
-
(1999)
Annals of Neurology
, vol.46
, Issue.1
, pp. 129-131
-
-
Tohgi, H.1
Abe, T.2
Yamizaki, K.3
Murata, T.4
Ishizaki, E.5
Isobe, C.6
-
88
-
-
18144398928
-
Protein nitration in a mouse model of familial amyotrophic lateral sclerosis: Possible multifunctional role in the pathogenesis
-
DOI 10.1074/jbc.M413111200
-
Casoni F., Basso M., Massignan T., Gianazzail E., Cheroni C., Salmona M., Bendotti C., Bonetto V., Protein nitration in a mouse model of familial amyotrophic lateral sclerosis: possible multifunctional role in the pathogenesis. Journal of Biological Chemistry 2005 280 16 16295 16304 2-s2.0-18144398928 10.1074/jbc.M413111200 (Pubitemid 40616757)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.16
, pp. 16295-16304
-
-
Casoni, F.1
Basso, M.2
Massignan, T.3
Gianazzail, E.4
Cheroni, C.5
Salmona, M.6
Bendotti, C.7
Bonetto, V.8
-
89
-
-
84859454704
-
An over-oxidized form of superoxide dismutase found in sporadic amyotrophic lateral sclerosis with bulbar onset shares a toxic mechanism with mutant SOD1
-
10.1073/pnas.1115402109
-
Guareschi S., Cova E., Cereda C., Ceroni M., Donetti E., Bosco D. A., Trotti D., Pasinelli P., An over-oxidized form of superoxide dismutase found in sporadic amyotrophic lateral sclerosis with bulbar onset shares a toxic mechanism with mutant SOD1. Proceedings of the National Academy of Sciences 2012 109 13 5074 5079 10.1073/pnas.1115402109
-
(2012)
Proceedings of the National Academy of Sciences
, vol.109
, Issue.13
, pp. 5074-5079
-
-
Guareschi, S.1
Cova, E.2
Cereda, C.3
Ceroni, M.4
Donetti, E.5
Bosco, D.A.6
Trotti, D.7
Pasinelli, P.8
-
90
-
-
48249103957
-
A systematic review of antioxidant treatment for amyotrophic lateral sclerosis/motor neuron disease
-
2-s2.0-48249103957 10.1080/17482960801900032
-
Orrell R. W., Lane R. J. M., Ross M., A systematic review of antioxidant treatment for amyotrophic lateral sclerosis/motor neuron disease. Amyotrophic Lateral Sclerosis 2008 9 4 195 211 2-s2.0-48249103957 10.1080/17482960801900032
-
(2008)
Amyotrophic Lateral Sclerosis
, vol.9
, Issue.4
, pp. 195-211
-
-
Orrell, R.W.1
Lane, R.J.M.2
Ross, M.3
-
91
-
-
34250177650
-
Wild-type superoxide dismutase acquires binding and toxic properties of ALS-linked mutant forms through oxidation
-
DOI 10.1111/j.1471-4159.2007.04531.x
-
Ezzi S. A., Urushitani M., Julien J. P., Wild-type superoxide dismutase acquires binding and toxic properties of ALS-linked mutant forms through oxidation. Journal of Neurochemistry 2007 102 1 170 178 2-s2.0-34250177650 10.1111/j.1471-4159.2007.04531.x (Pubitemid 46906269)
-
(2007)
Journal of Neurochemistry
, vol.102
, Issue.1
, pp. 170-178
-
-
Ezzi, S.A.1
Urushitani, M.2
Julien, J.-P.3
-
92
-
-
80051503291
-
Glutathionylation at Cys-111 induces dissociation of wild type and FALS mutant SOD1 dimers
-
10.1021/bi200614y
-
Redler R. L., Wilcox K. C., Proctor E. A., Fee L., Caplow M., Dokholyan N. V., Glutathionylation at Cys-111 induces dissociation of wild type and FALS mutant SOD1 dimers. Biochemistry 2011 50 32 7057 7066 10.1021/bi200614y
-
(2011)
Biochemistry
, vol.50
, Issue.32
, pp. 7057-7066
-
-
Redler, R.L.1
Wilcox, K.C.2
Proctor, E.A.3
Fee, L.4
Caplow, M.5
Dokholyan, N.V.6
-
93
-
-
77955352066
-
Novel antibodies reveal inclusions containing non-native SOD1 in sporadic ALS patients
-
e11552 10.1371/journal.pone.0011552
-
Forsberg K., Jonsson P. A., Andersen P. M., Bergemalm D., Graffmo K. S., Hultdin M., Jacobsson J., Rosquist R., Marklund S. L., Brannstrom T., Novel antibodies reveal inclusions containing non-native SOD1 in sporadic ALS patients. PloS One 2010 5 7 e11552 10.1371/journal.pone.0011552
-
(2010)
PloS One
, vol.5
, Issue.7
-
-
Forsberg, K.1
Jonsson, P.A.2
Andersen, P.M.3
Bergemalm, D.4
Graffmo, K.S.5
Hultdin, M.6
Jacobsson, J.7
Rosquist, R.8
Marklund, S.L.9
Brannstrom, T.10
-
94
-
-
77958519939
-
Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS
-
2-s2.0-77958519939 10.1038/nn.2660
-
Bosco D. A., Morfini G., Karabacak N. M., Song Y., Gros-Louis F., Pasinelli P., Goolsby H., Fontaine B. A., Lemay N., McKenna-Yasek D., Frosch M. P., Agar J. N., Julien J. P., Brady S. T., Brown R. H. Jr., Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS. Nature Neuroscience 2010 13 11 1396 1403 2-s2.0-77958519939 10.1038/nn.2660
-
(2010)
Nature Neuroscience
, vol.13
, Issue.11
, pp. 1396-1403
-
-
Bosco, D.A.1
Morfini, G.2
Karabacak, N.M.3
Song, Y.4
Gros-Louis, F.5
Pasinelli, P.6
Goolsby, H.7
Fontaine, B.A.8
Lemay, N.9
McKenna-Yasek, D.10
Frosch, M.P.11
Agar, J.N.12
Julien, J.P.13
Brady, S.T.14
Brown Jr., R.H.15
-
95
-
-
0039251419
-
Induction of nitric oxide-dependent apoptosis in motor neurons by zinc- deficient superoxide dismutase
-
DOI 10.1126/science.286.5449.2498
-
Estévez A. C., Crow J. P., Sampson J. B., Reiter C., Zhuang Y., Richardson G. J., Tarpey M. M., Barbeito L., Beckman J. S., Induction of nitric oxide-dependent apoptosis in motor neurons by zinc- deficient superoxide dismutase. Science 1999 286 5449 2498 2500 2-s2.0-0039251419 10.1126/science.286.5449.2498 (Pubitemid 30026336)
-
(1999)
Science
, vol.286
, Issue.5449
, pp. 2498-2500
-
-
Estevez, A.C.1
Crow, J.P.2
Sampson, J.B.3
Reiter, C.4
Zhuang, Y.5
Richardson, G.J.6
Tarpey, M.M.7
Barbeito, L.8
Beckman, J.S.9
-
96
-
-
33646486372
-
Disulfide cross-linked protein represents a significant fraction of ALS-associated Cu, Zn-superoxide dismutase aggregates in spinal cords of model mice
-
2-s2.0-33646486372 10.1073/pnas.0602048103
-
Furukawa Y., Fu R., Deng H. X., Siddique T., O'Halloran T. V., Disulfide cross-linked protein represents a significant fraction of ALS-associated Cu, Zn-superoxide dismutase aggregates in spinal cords of model mice. Proceedings of the National Academy of Sciences of the United States of America 2006 103 18 7148 7153 2-s2.0-33646486372 10.1073/pnas.0602048103
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.18
, pp. 7148-7153
-
-
Furukawa, Y.1
Fu, R.2
Deng, H.X.3
Siddique, T.4
O'Halloran, T.V.5
-
97
-
-
84857997227
-
Redox signalling directly regulates TDP-43 via cysteine oxidation and disulphide cross-linking
-
10.1038/emboj.2011.471
-
Cohen T. J., Hwang A. W., Unger T., Trojanowski J. Q., Lee V. M. Y., Redox signalling directly regulates TDP-43 via cysteine oxidation and disulphide cross-linking. The EMBO Journal 2011 31 5 1241 1252 10.1038/emboj.2011.471
-
(2011)
The EMBO Journal
, vol.31
, Issue.5
, pp. 1241-1252
-
-
Cohen, T.J.1
Hwang, A.W.2
Unger, T.3
Trojanowski, J.Q.4
Lee, V.M.Y.5
-
98
-
-
77955792022
-
ALS-associated fused in sarcoma (FUS) mutations disrupt transportin-mediated nuclear import
-
2-s2.0-77955792022 10.1038/emboj.2010.143
-
Dormann D., Rodde R., Edbauer D., Bentmann E., Fischer I., Hruscha A., Than M. E., MacKenzie I. R. A., Capell A., Schmid B., Neumann M., Haass C., ALS-associated fused in sarcoma (FUS) mutations disrupt transportin-mediated nuclear import. EMBO Journal 2010 29 16 2841 2857 2-s2.0-77955792022 10.1038/emboj.2010.143
-
(2010)
EMBO Journal
, vol.29
, Issue.16
, pp. 2841-2857
-
-
Dormann, D.1
Rodde, R.2
Edbauer, D.3
Bentmann, E.4
Fischer, I.5
Hruscha, A.6
Than, M.E.7
MacKenzie, I.R.A.8
Capell, A.9
Schmid, B.10
Neumann, M.11
Haass, C.12
-
99
-
-
0023103345
-
In vivo studies on the extracellular, and veratrine-releasable, pools of endogenous amino acids in the rat striatum: Effects of corticostriatal deafferentiation and kainic acid lesion
-
DOI 10.1111/j.1471-4159.1987.tb05575.x
-
Butcher S. P., Hamberger A., In vivo studies on the extracellular, and veratrine-releasable, pools of endogenous amino acids in the rat striatum: effects of corticostriatal deafferentiation and kainic acid lesion. Journal of Neurochemistry 1987 48 3 713 721 2-s2.0-0023103345 (Pubitemid 17018699)
-
(1987)
Journal of Neurochemistry
, vol.48
, Issue.3
, pp. 713-721
-
-
Butcher, S.P.1
Hamberger, A.2
-
100
-
-
22844453146
-
Cerebrospinal fluid from amyotrophic lateral sclerosis patients preferentially elevates intracellular calcium and toxicity in motor neurons via AMPA/kainate receptor
-
DOI 10.1016/j.jns.2005.03.049, PII S0022510X05001425
-
Sen I., Nalini A., Joshi N. B., Joshi P. G., Cerebrospinal fluid from amyotrophic lateral sclerosis patients preferentially elevates intracellular calcium and toxicity in motor neurons via AMPA/kainate receptor. Journal of the Neurological Sciences 2005 235 1-2 45 54 2-s2.0-22844453146 10.1016/j.jns.2005. 03.049 (Pubitemid 41039092)
-
(2005)
Journal of the Neurological Sciences
, vol.235
, Issue.1-2
, pp. 45-54
-
-
Sen, I.1
Nalini, A.2
Joshi, N.B.3
Joshi, P.G.4
-
101
-
-
0023617392
-
Abnormal glutamate metabolism in amyotrophic lateral sclerosis
-
DOI 10.1002/ana.410220503
-
Plaitakis A., Caroscio J. T., Abnormal glutamate metabolism in amyotrophic lateral sclerosis. Annals of Neurology 1987 22 5 575 579 2-s2.0-0023617392 (Pubitemid 17162898)
-
(1987)
Annals of Neurology
, vol.22
, Issue.5
, pp. 575-579
-
-
Plaitakis, A.1
Caroscio, J.T.2
-
102
-
-
0034319259
-
Different receptors mediate motor neuron death induced by short and long exposures to excitotoxicity
-
DOI 10.1016/S0361-9230(00)00371-3, PII S0361923000003713
-
Van Den Bosch L., Robberecht W., Different receptors mediate motor neuron death induced by short and long exposures to excitotoxicity. Brain Research Bulletin 2000 53 4 383 388 2-s2.0-0034319259 10.1016/S0361-9230(00)00371-3 (Pubitemid 32000814)
-
(2000)
Brain Research Bulletin
, vol.53
, Issue.4
, pp. 383-388
-
-
Van Den Bosch, L.1
Robberecht, W.2
-
103
-
-
0031001036
-
Neuronal and glial glutamate transporters possess an SH-based redox regulatory mechanism
-
DOI 10.1111/j.1460-9568.1997.tb01478.x
-
Trotti D., Neuronal and glial glutamate transporters possess an SH-based redox regulatory mechanism. European Journal of Neuroscience 1997 9 6 1236 1243 2-s2.0-0031001036 10.1111/j.1460-9568.1997.tb01478.x (Pubitemid 27260752)
-
(1997)
European Journal of Neuroscience
, vol.9
, Issue.6
, pp. 1236-1243
-
-
Trotti, D.1
-
104
-
-
0027483169
-
Altered metabolism of excitatory amino acids, N-acetyl-aspartate and N- acetyl-aspartyl-glutamate in amyotrophic lateral sclerosis
-
Plaitakis A., Constantakakis E., Altered metabolism of excitatory amino acids, N-acetyl-aspartate and N- acetyl-aspartyl-glutamate in amyotrophic lateral sclerosis. Brain Research Bulletin 1993 30 3-4 381 386 2-s2.0-0027483169 (Pubitemid 23072747)
-
(1993)
Brain Research Bulletin
, vol.30
, Issue.3-4
, pp. 381-386
-
-
Plaitakis, A.1
Constantakakis, E.2
-
105
-
-
0026597010
-
Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis
-
2-s2.0-0026597010
-
Rothstein J. D., Martin L. J., Kuncl R. W., Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis. New England Journal of Medicine 1992 326 22 1464 1468 2-s2.0-0026597010
-
(1992)
New England Journal of Medicine
, vol.326
, Issue.22
, pp. 1464-1468
-
-
Rothstein, J.D.1
Martin, L.J.2
Kuncl, R.W.3
-
106
-
-
0029030610
-
Selective loss of glial glutamate transporter GLT-1 amyotrophic lateral sclerosis
-
2-s2.0-0029030610 10.1002/ana.410380114
-
Rothstein J. D., Van Kammen M., Levey A. I., Martin L. J., Kuncl R. W., Selective loss of glial glutamate transporter GLT-1 amyotrophic lateral sclerosis. Annals of Neurology 1995 38 1 73 84 2-s2.0-0029030610 10.1002/ana.410380114
-
(1995)
Annals of Neurology
, vol.38
, Issue.1
, pp. 73-84
-
-
Rothstein, J.D.1
Van Kammen, M.2
Levey, A.I.3
Martin, L.J.4
Kuncl, R.W.5
-
107
-
-
0028208495
-
Glutamate uptake inhibition by oxygen free radicals in rat cortical astrocytes
-
Volterra A., Trotti D., Tromba C., Floridi S., Racagni G., Glutamate uptake inhibition by oxygen free radicals in rat cortical astrocytes. Journal of Neuroscience 1994 14 5 2924 2932 2-s2.0-0028208495 (Pubitemid 24140915)
-
(1994)
Journal of Neuroscience
, vol.14
, Issue.5
, pp. 2924-2932
-
-
Volterra, A.1
Trotti, D.2
Tromba, C.3
Floridi, S.4
Racagni, G.5
-
108
-
-
0030927075
-
Glutamate, excitotoxicity and amyotrophic lateral sclerosis
-
Shaw P. J., Glutamate, excitotoxicity and amyotrophic lateral sclerosis. Journal of Neurology 1997 244 2 S3 S14 2-s2.0-0030927075 (Pubitemid 27208005)
-
(1997)
Journal of Neurology, Supplement
, vol.244
, Issue.2
-
-
Shaw, P.J.1
-
109
-
-
18844367746
-
Minireview: Regulation of steroidogenesis by electron transfer
-
DOI 10.1210/en.2005-0096
-
Miller W. L., Minireview: regulation of steroidogenesis by electron transfer. Endocrinology 2005 146 6 2544 2550 2-s2.0-18844367746 10.1210/en.2005-0096 (Pubitemid 40695556)
-
(2005)
Endocrinology
, vol.146
, Issue.6
, pp. 2544-2550
-
-
Miller, W.L.1
-
110
-
-
79960427714
-
Lipid raft redox signaling: Molecular mechanisms in health and disease
-
2-s2.0-79960427714 10.1089/ars.2010.3619
-
Jin S., Zhou F., Katirai F., Li P. L., Lipid raft redox signaling: molecular mechanisms in health and disease. Antioxidants and Redox Signaling 2011 15 4 1043 1083 2-s2.0-79960427714 10.1089/ars.2010.3619
-
(2011)
Antioxidants and Redox Signaling
, vol.15
, Issue.4
, pp. 1043-1083
-
-
Jin, S.1
Zhou, F.2
Katirai, F.3
Li, P.L.4
-
111
-
-
0031768026
-
Protein modification by the lipid peroxidation product 4-hydroxynonenal in the spinal cords of amyotrophic lateral sclerosis patients
-
Pedersen W. A., Fu W., Keller J. N., Markesbery W. R., Appel S., Smith R. G., Kasarskis E., Mattson M. P., Protein modification by the lipid peroxidation product 4-hydroxynonenal in the spinal cords of amyotrophic lateral sclerosis patients. Annals of Neurology 1998 44 5 819 824 2-s2.0-0031768026 (Pubitemid 28516055)
-
(1998)
Annals of Neurology
, vol.44
, Issue.5
, pp. 819-824
-
-
Pedersen, W.A.1
Fu, W.2
Keller, J.N.3
Markesbery, W.R.4
Appel, S.5
Smith, R.G.6
Kasarskis, E.7
Mattson, M.P.8
-
112
-
-
41349122697
-
Dyslipidemia is a protective factor in amyotrophic lateral sclerosis
-
DOI 10.1212/01.wnl.0000285080.70324.27
-
Dupuis L., Corcia P., Fergani A., Gonzalez De Aguilar J. L., Bonnefont-Rousselot D., Bittar R., Seilhean D., Hauw J. J., Lacomblez L., Loeffler J. P., Meininger V., Dyslipidemia is a protective factor in amyotrophic lateral sclerosis. Neurology 2008 70 13 1004 1009 2-s2.0-41349122697 10.1212/01.wnl.0000285080.70324.27 (Pubitemid 351451324)
-
(2008)
Neurology
, vol.70
, Issue.13 PART 1
, pp. 1004-1009
-
-
Dupuis, L.1
Corcia, P.2
Fergani, A.3
Gonzalez De Aguilar, J.-L.4
Bonnefont-Rousselot, D.5
Bittar, R.6
Seilhean, D.7
Hauw, J.-J.8
Lacomblez, L.9
Loeffler, J.-P.10
Meininger, V.11
-
113
-
-
65949094823
-
Neuromuscular junction destruction during amyotrophic lateral sclerosis: Insights from transgenic models
-
2-s2.0-65949094823 10.1016/j.coph.2009.03.007
-
Dupuis L., Loeffler J. P., Neuromuscular junction destruction during amyotrophic lateral sclerosis: insights from transgenic models. Current Opinion in Pharmacology 2009 9 3 341 346 2-s2.0-65949094823 10.1016/j.coph.2009.03.007
-
(2009)
Current Opinion in Pharmacology
, vol.9
, Issue.3
, pp. 341-346
-
-
Dupuis, L.1
Loeffler, J.P.2
-
114
-
-
84555203235
-
Direct observation of defects and increased ion permeability of a membrane induced by structurally disordered Cu/Zn-superoxide dismutase aggregates
-
10.1371/journal.pone.0028982
-
Choi I., Song H. D., Lee S., Yang Y. I., Nam J. H., Kim S. J., Sung J. J., Kang T., Yi J., Direct observation of defects and increased ion permeability of a membrane induced by structurally disordered Cu/Zn-superoxide dismutase aggregates. PloS One 2011 6 12 e28982 e28982 10.1371/journal.pone.0028982
-
(2011)
PloS One
, vol.6
, Issue.12
-
-
Choi, I.1
Song, H.D.2
Lee, S.3
Yang, Y.I.4
Nam, J.H.5
Kim, S.J.6
Sung, J.J.7
Kang, T.8
Yi, J.9
-
115
-
-
80053122133
-
Sterol regulatory element binding protein-1 (SREBP1) activation in motor neurons in excitotoxicity and amyotrophic lateral sclerosis (ALS): Indip, a potential therapeutic peptide
-
10.1016/j.bbrc.2011.08.011
-
Taghibiglou C., Lu J., Mackenzie I. R., Wang Y. T., Cashman N. R., Sterol regulatory element binding protein-1 (SREBP1) activation in motor neurons in excitotoxicity and amyotrophic lateral sclerosis (ALS): indip, a potential therapeutic peptide. Biochemical and Biophysical Research Communications 2011 413 2 159 163 10.1016/j.bbrc.2011.08.011
-
(2011)
Biochemical and Biophysical Research Communications
, vol.413
, Issue.2
, pp. 159-163
-
-
Taghibiglou, C.1
Lu, J.2
MacKenzie, I.R.3
Wang, Y.T.4
Cashman, N.R.5
-
116
-
-
57649218663
-
An evaluation of a data mining signal for amyotrophic lateral sclerosis and statins detected in FDA's spontaneous adverse event reporting system
-
2-s2.0-57649218663 10.1002/pds.1643
-
Colman E., Szarfman A., Wyeth J., Mosholder A., Jillapalli D., Levine J., Avigan M., An evaluation of a data mining signal for amyotrophic lateral sclerosis and statins detected in FDA's spontaneous adverse event reporting system. Pharmacoepidemiology and Drug Safety 2008 17 11 1068 1076 2-s2.0-57649218663 10.1002/pds.1643
-
(2008)
Pharmacoepidemiology and Drug Safety
, vol.17
, Issue.11
, pp. 1068-1076
-
-
Colman, E.1
Szarfman, A.2
Wyeth, J.3
Mosholder, A.4
Jillapalli, D.5
Levine, J.6
Avigan, M.7
-
117
-
-
34249902026
-
Statins, neuromuscular degenerative disease and an amyotrophic lateral sclerosis-like syndrome: An analysis of individual case safety reports from vigibase
-
DOI 10.2165/00002018-200730060-00005
-
Edwards I. R., Star K., Kiuru A., Statins, neuromuscular degenerative disease and an amyotrophic lateral sclerosis-like syndrome: an analysis of individual case safety reports from vigibase. Drug Safety 2007 30 6 515 525 2-s2.0-34249902026 10.2165/00002018-200730060-00005 (Pubitemid 46873076)
-
(2007)
Drug Safety
, vol.30
, Issue.6
, pp. 515-525
-
-
Edwards, I.R.1
Star, K.2
Kiuru, A.3
-
118
-
-
48249090462
-
Are statin medications safe in patients with ALS?
-
2-s2.0-48249090462 10.1080/17482960802031092
-
Zinman L., Sadeghi R., Gawel M., Patton D., Kiss A., Are statin medications safe in patients with ALS? Amyotrophic Lateral Sclerosis 2008 9 4 223 228 2-s2.0-48249090462 10.1080/17482960802031092
-
(2008)
Amyotrophic Lateral Sclerosis
, vol.9
, Issue.4
, pp. 223-228
-
-
Zinman, L.1
Sadeghi, R.2
Gawel, M.3
Patton, D.4
Kiss, A.5
-
119
-
-
70449417612
-
Statins and amyotrophic lateral sclerosis - The level of evidence for an association
-
2-s2.0-70449417612 10.1111/j.1365-2796.2009.02173.x
-
Toft Sørensen H., Lash T. L., Statins and amyotrophic lateral sclerosis-the level of evidence for an association. Journal of Internal Medicine 2009 266 6 520 526 2-s2.0-70449417612 10.1111/j.1365-2796.2009.02173.x
-
(2009)
Journal of Internal Medicine
, vol.266
, Issue.6
, pp. 520-526
-
-
Toft Sørensen, H.1
Lash, T.L.2
-
120
-
-
66249085542
-
Proteomic characterization of lipid raft proteins in amyotrophic lateral sclerosis mouse spinal cord
-
2-s2.0-66249085542 10.1111/j.1742-4658.2009.07057.x
-
Zhai J., Ström A. L., Kilty R., Venkatakrishnan P., White J., Everson W. V., Smart E. J., Zhu H., Proteomic characterization of lipid raft proteins in amyotrophic lateral sclerosis mouse spinal cord. FEBS Journal 2009 276 12 3308 3323 2-s2.0-66249085542 10.1111/j.1742-4658.2009.07057.x
-
(2009)
FEBS Journal
, vol.276
, Issue.12
, pp. 3308-3323
-
-
Zhai, J.1
Ström, A.L.2
Kilty, R.3
Venkatakrishnan, P.4
White, J.5
Everson, W.V.6
Smart, E.J.7
Zhu, H.8
-
121
-
-
0029125857
-
Aging, energy, and oxidative stress in neurodegenerative diseases
-
2-s2.0-0029125857 10.1002/ana.410380304
-
Beal M. F., Aging, energy, and oxidative stress in neurodegenerative diseases. Annals of Neurology 1995 38 3 357 366 2-s2.0-0029125857 10.1002/ana.410380304
-
(1995)
Annals of Neurology
, vol.38
, Issue.3
, pp. 357-366
-
-
Beal, M.F.1
-
122
-
-
0036321382
-
Mitochondrial DNA and respiratory chain function in spinal cords of ALS patients
-
DOI 10.1046/j.0022-3042.2001.00731.x
-
Wiedemann F. R., Manfredi G., Mawrin C., Flint Beal M., Schon E. A., Mitochondrial DNA and respiratory chain function in spinal cords of ALS patients. Journal of Neurochemistry 2002 80 4 616 625 2-s2.0-0036321382 10.1046/j.0022-3042.2001.00731.x (Pubitemid 34809970)
-
(2002)
Journal of Neurochemistry
, vol.80
, Issue.4
, pp. 616-625
-
-
Wiedemann, F.R.1
Manfredi, G.2
Mawrin, C.3
Flint Beal, M.4
Schon, E.A.5
-
123
-
-
0032745071
-
Mitochondrial enzyme activity in amyotrophic lateral sclerosis: Implications for the role of mitochondria in neuronal cell death
-
DOI 10.1002/1531-8249(199 911)46:5<787::AID-AN A17>3.0.CO;2-8
-
Borthwick G. M., Johnson M. A., Ince P. G., Shaw P. J., Turnbull D. M., Mitochondrial enzyme activity in amyotrophic lateral sclerosis: implications for the role of mitochondria in neuronal cell death. Annals of Neurology 2001 46 5 787 790 (Pubitemid 29518143)
-
(1999)
Annals of Neurology
, vol.46
, Issue.5
, pp. 787-790
-
-
Borthwick, G.M.1
Johnson, M.A.2
Ince, P.G.3
Shaw, P.J.4
Turnbull, D.M.5
-
124
-
-
77952638633
-
ALS spinal neurons show varied and reduced mtDNA gene copy numbers and increased mtDNA gene deletions
-
2-s2.0-77952638633 10.1186/1750-1326-5-21
-
Keeney P. M., Bennett J. P., ALS spinal neurons show varied and reduced mtDNA gene copy numbers and increased mtDNA gene deletions. Molecular Neurodegeneration 2010 5 1 21 2-s2.0-77952638633 10.1186/1750-1326-5-21
-
(2010)
Molecular Neurodegeneration
, vol.5
, Issue.1
, pp. 21
-
-
Keeney, P.M.1
Bennett, J.P.2
-
125
-
-
0032053584
-
Neurodegeneration and aging: Role of the second genome
-
DOI 10.1002/(SICI)1097-4547(19980 401)52:1<1::AID-JN R1>3.0.CO;2-I
-
Graeber M. B., Grasbon-Frodl E., Eitzen U. V., Kösel S. K., Neurodegeneration and aging: role of the second genome. Journal of Neuroscience Research 1998 52 1 1 6 10.1002/(SICI)1097-4547(19980401)52:1<1::AID- JNR1>3.0.CO;2-I (Pubitemid 28158820)
-
(1998)
Journal of Neuroscience Research
, vol.52
, Issue.1
, pp. 1-6
-
-
Graeber, M.B.1
Grasbon-Frodl, E.2
Eitzen, U.V.3
Kosel, S.4
-
126
-
-
0035676977
-
The machinery of programmed cell death
-
DOI 10.1016/S0163-7258(01)00159-0, PII S0163725801001590
-
Zimmermann K. C., Bonzon C., Green D. R., The machinery of programmed cell death. Pharmacology and Therapeutics 2001 92 1 57 70 2-s2.0-0035676977 10.1016/S0163-7258(01)00159-0 (Pubitemid 34032022)
-
(2001)
Pharmacology and Therapeutics
, vol.92
, Issue.1
, pp. 57-70
-
-
Zimmermann, K.C.1
Bonzon, C.2
Green, D.R.3
-
127
-
-
71849098808
-
Multifaceted deaths orchestrated by mitochondria in neurones
-
2-s2.0-71849098808 10.1016/j.bbadis.2009.09.004
-
Nagley P., Higgins G. C., Atkin J. D., Beart P. M., Multifaceted deaths orchestrated by mitochondria in neurones. Biochimica et Biophysica Acta 2010 1802 1 167 185 2-s2.0-71849098808 10.1016/j.bbadis.2009.09.004
-
(2010)
Biochimica et Biophysica Acta
, vol.1802
, Issue.1
, pp. 167-185
-
-
Nagley, P.1
Higgins, G.C.2
Atkin, J.D.3
Beart, P.M.4
-
128
-
-
0035437866
-
Recruitment of the mitochondria-dependent apoptotic pathway in amyotrophic lateral sclerosis
-
Guégan C., Vila M., Rosoklija G., Hays A. P., Przedborski S., Recruitment of the mitochondria-dependent apoptotic pathway in amyotrophic lateral sclerosis. Journal of Neuroscience 2001 21 17 6569 6576 2-s2.0-0035437866 (Pubitemid 32781101)
-
(2001)
Journal of Neuroscience
, vol.21
, Issue.17
, pp. 6569-6576
-
-
Guegan, C.1
Vila, M.2
Rosoklija, G.3
Hays, A.P.4
Przedborski, S.5
-
129
-
-
33845361630
-
Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: Mechanisms of mitochondriopathy and cell death
-
DOI 10.1002/cne.21160
-
Martin L. J., Liu Z., Chen K., Price A. C., Yan P., Swaby J. A., Golden W. C., Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: mechanisms of mitochondriopathy and cell death. Journal of Comparative Neurology 2007 500 1 20 46 2-s2.0-33845361630 10.1002/cne.21160 (Pubitemid 44904300)
-
(2007)
Journal of Comparative Neurology
, vol.500
, Issue.1
, pp. 20-46
-
-
Martin, L.J.1
Liu, Z.2
Chen, K.3
Price, A.C.4
Yan, P.5
Swaby, J.A.6
Golden, W.C.7
-
130
-
-
0029053881
-
An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria
-
2-s2.0-0029053881
-
Wong P. C., Pardo C. A., Borchelt D. R., Lee M. K., Copeland N. G., Jenkins N. A., Sisodia S. S., Cleveland D. W., Price D. L., An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron 1995 14 6 1105 1116 2-s2.0-0029053881
-
(1995)
Neuron
, vol.14
, Issue.6
, pp. 1105-1116
-
-
Wong, P.C.1
Pardo, C.A.2
Borchelt, D.R.3
Lee, M.K.4
Copeland, N.G.5
Jenkins, N.A.6
Sisodia, S.S.7
Cleveland, D.W.8
Price, D.L.9
-
131
-
-
0036310142
-
Mitochondrial dysfunction in a cell culture model of familial amyotrophic lateral sclerosis
-
Menzies F. M., Cookson M. R., Taylor R. W., Turnbull D. M., Chrzanowska-Lightowlers Z. M. A., Dong L., Figlewicz D. A., Shaw P. J., Mitochondrial dysfunction in a cell culture model of familial amyotrophic lateral sclerosis. Brain 2002 125 7 1522 1533 2-s2.0-0036310142 (Pubitemid 34755167)
-
(2002)
Brain
, vol.125
, Issue.7
, pp. 1522-1533
-
-
Menzies, F.M.1
Cookson, M.R.2
Taylor, R.W.3
Turnbull, D.M.4
Chrzanowska- Lightowlers, Z.M.A.5
Dong, L.6
Figlewicz, D.A.7
Shaw, P.J.8
-
132
-
-
0031559896
-
2+ concentration in transfected neuroblastoma SH-SY5Y cells
-
DOI 10.1016/S0014-5793(97)01051-X, PII S001457939701051X
-
Carrì M. T., Ferri A., Battistoni A., Famhy L., Gabbianelli R., Poccia F., Rotilio G., Expression of a Cu,Zn superoxide dismutase typical of familial amyotrophic lateral sclerosis induces mitochondrial alteration and increase of cytosolic Ca2+ concentration in transfected neuroblastoma SH-SY5Y cells. FEBS Letters 1997 414 2 365 368 2-s2.0-0031559896 10.1016/S0014-5793(97) 01051-X (Pubitemid 27389396)
-
(1997)
FEBS Letters
, vol.414
, Issue.2
, pp. 365-368
-
-
Carri, M.T.1
Ferri, A.2
Battistoni, A.3
Famhy, L.4
Gabbianelli, R.5
Poccia, F.6
Rotilio, G.7
-
133
-
-
0030019414
-
Ultrastructural study of synapses in the anterior horn neurons of patients with amyotrophic lateral sclerosis
-
DOI 10.1016/0304-3940(96)12314-4
-
Sasaki S., Iwata M., Ultrastructural study of synapses in the anterior horn neurons of patients with amyotrophic lateral sclerosis. Neuroscience Letters 1996 204 1-2 53 56 2-s2.0-0030019414 10.1016/0304-3940(96)12314-4 (Pubitemid 26053674)
-
(1996)
Neuroscience Letters
, vol.204
, Issue.1-2
, pp. 53-56
-
-
Sasaki, S.1
Iwata, M.2
-
134
-
-
0030026832
-
Ultrastructural evidence for altered calcium in motor nerve terminals in amyotrophic lateral sclerosis
-
DOI 10.1002/ana.410390210
-
Siklós L., Engelhardt J., Harati Y., Smith R. G., Joó F., Appel S. H., Ultrastructural evidence for altered calcium in motor nerve terminals in amyotrophic lateral sclerosis. Annals of Neurology 1996 39 2 203 216 2-s2.0-0030026832 10.1002/ana.410390210 (Pubitemid 26071571)
-
(1996)
Annals of Neurology
, vol.39
, Issue.2
, pp. 203-216
-
-
Siklos, L.1
Engelhardt, J.2
Harati, Y.3
Smith, R.G.4
Joo, F.5
Appel, S.H.6
-
135
-
-
84860650335
-
Mitochondrial dysfunction in ALS
-
10.1016/j.pneurobio.2011.06.003
-
Cozzolino M., Carrí M. T., Mitochondrial dysfunction in ALS. Progress in Neurobiology 2012 97 2 54 66 10.1016/j.pneurobio.2011.06.003
-
(2012)
Progress in Neurobiology
, vol.97
, Issue.2
, pp. 54-66
-
-
Cozzolino, M.1
Carrí, M.T.2
-
136
-
-
84859867839
-
Bim links ER stress and apoptosis in cells expressing mutant SOD1 associated with amyotrophic lateral sclerosis
-
e35413
-
Soo K. Y., Atkin J. D., Farg M., Walker A. K., Horne M. K., Nagley P., Bim links ER stress and apoptosis in cells expressing mutant SOD1 associated with amyotrophic lateral sclerosis. PloS One 2012 7 4 e35413
-
(2012)
PloS One
, vol.7
, Issue.4
-
-
Soo, K.Y.1
Atkin, J.D.2
Farg, M.3
Walker, A.K.4
Horne, M.K.5
Nagley, P.6
-
137
-
-
84868452494
-
Full-length TDP-43 and its C-terminal fragments activate mitophagy in NSC34 cell line
-
10.1016/j.neulet.2012.10.003
-
Hong K., Li Y., Duan W., Guo Y., Jiang H., Li W., Li C., Full-length TDP-43 and its C-terminal fragments activate mitophagy in NSC34 cell line. Neuroscience Letters 2012 530 2 144 149 10.1016/j.neulet.2012.10.003
-
(2012)
Neuroscience Letters
, vol.530
, Issue.2
, pp. 144-149
-
-
Hong, K.1
Li, Y.2
Duan, W.3
Guo, Y.4
Jiang, H.5
Li, W.6
Li, C.7
-
138
-
-
80053355702
-
Mitochondrial dynamics in yeast cell death and aging
-
10.1042/BST0391520
-
Braun R. J., Westermann B., Mitochondrial dynamics in yeast cell death and aging. Biochemical Society Transactions 2011 39 1520 1526 10.1042/BST0391520
-
(2011)
Biochemical Society Transactions
, vol.39
, pp. 1520-1526
-
-
Braun, R.J.1
Westermann, B.2
-
139
-
-
77955423158
-
Mutant TAR DNA-binding protein-43 induces oxidative injury in motor neuron-like cell
-
2-s2.0-77955423158 10.1016/j.neuroscience.2010.06.018
-
Duan W., Li X., Shi J., Guo Y., Li Z., Li C., Mutant TAR DNA-binding protein-43 induces oxidative injury in motor neuron-like cell. Neuroscience 2010 169 4 1621 1629 2-s2.0-77955423158 10.1016/j.neuroscience.2010.06.018
-
(2010)
Neuroscience
, vol.169
, Issue.4
, pp. 1621-1629
-
-
Duan, W.1
Li, X.2
Shi, J.3
Guo, Y.4
Li, Z.5
Li, C.6
-
140
-
-
0036830072
-
Mitochondrial electron transport chain complex dysfunction in a transgenic mouse model for amyotrophic lateral sclerosis
-
DOI 10.1046/j.1471-4159.2002.01112.x
-
Jung C., Higgins C. M. J., Xu Z., Mitochondrial electron transport chain complex dysfunction in a transgenic mouse model for amyotrophic lateral sclerosis. Journal of Neurochemistry 2002 83 3 535 545 2-s2.0-0036830072 10.1046/j.1471-4159.2002.01112.x (Pubitemid 35231807)
-
(2002)
Journal of Neurochemistry
, vol.83
, Issue.3
, pp. 535-545
-
-
Jung, C.1
Higgins, C.M.J.2
Xu, Z.3
-
141
-
-
33748795566
-
Familial ALS-superoxide dismutases associate with mitochondria and shift their redox potentials
-
DOI 10.1073/pnas.0605814103
-
Ferri A., Cozzolino M., Crosio C., Nencini M., Casciati A., Gralla E. B., Rotilio G., Valentine J. S., Carri M. T., Familial ALS-superoxide dismutases associate with mitochondria and shift their redox potentials. Proceedings of the National Academy of Sciences of the United States of America 2006 103 37 13860 13865 2-s2.0-33748795566 10.1073/pnas.0605814103 (Pubitemid 44413998)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.37
, pp. 13860-13865
-
-
Ferri, A.1
Cozzolino, M.2
Crosio, C.3
Nencini, M.4
Casciati, A.5
Gralla, E.B.6
Rotilio, G.7
Valentine, J.S.8
Carri, M.T.9
-
142
-
-
33845602614
-
Mitochondrial damage due to SOD1 deficiency in SH-SY5Y neuroblastoma cells: A rationale for the redundancy of SOD1
-
DOI 10.1096/fj.05-5225fje
-
Aquilano K., Vigilanza P., Rotilio G., Ciriolo M. R., Mitochondrial damage due to SOD1 deficiency in SH-SY5Y neuroblastoma cells: a rationale for the redundancy of SOD1. The FASEB Journal 2006 20 10 1683 1685 2-s2.0-33749327294 10.1096/fj.05-5225fje (Pubitemid 44943772)
-
(2006)
FASEB Journal
, vol.20
, Issue.10
-
-
Aquilano, K.1
Vigilanza, P.2
Rotilio, G.3
Ciriolo, M.R.4
-
143
-
-
10644296999
-
Mitochondrial protein oxidation in yeast mutants lacking manganese- (MnSOD) or copper- and zinc-containing superoxide dismutase (CuZnSOD): Evidence that mnsod and cuznsod have both unique and overlapping functions in protecting mitochondrial proteins from oxidative damage
-
DOI 10.1074/jbc.M405958200
-
O'Brien E. M., Dirmeier R., Engle M., Poyton R. O., Mitochondrial protein oxidation in yeast mutants lacking manganese- (MnSOD) or copper- and zinc-containing superoxide dismutase (CuZnSOD): evidence that mnsod and cuznsod have both unique and overlapping functions in protecting mitochondrial proteins from oxidative damage. Journal of Biological Chemistry 2004 279 50 51817 51827 2-s2.0-10644296999 10.1074/jbc.M405958200 (Pubitemid 39656548)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.50
, pp. 51817-51827
-
-
O'Brien, E.M.1
Dirmeier, R.2
Engle, M.3
Poyton, R.O.4
-
144
-
-
84861596118
-
Misfolded SOD1 and ALS: Zeroing in on mitochondria
-
Pickles S., Velde C. V., Misfolded SOD1 and ALS: zeroing in on mitochondria. Amyotrophic Lateral Sclerosis 2012 13 333 340
-
(2012)
Amyotrophic Lateral Sclerosis
, vol.13
, pp. 333-340
-
-
Pickles, S.1
Velde, C.V.2
-
145
-
-
0025309791
-
Mitochondrial mutations may increase oxidative stress: Implications for carcinogenesis and aging?
-
DOI 10.1016/0891-5849(90)90152-9
-
Bandy B., Davison A. J., Mitochondrial mutations may increase oxidative stress: implications for carcinogenesis and aging? Free Radical Biology and Medicine 1990 8 6 523 539 2-s2.0-0025309791 10.1016/0891-5849(90)90152-9 (Pubitemid 20204417)
-
(1990)
Free Radical Biology and Medicine
, vol.8
, Issue.6
, pp. 523-539
-
-
Bandy, B.1
Davison, A.J.2
-
146
-
-
34447550238
-
Interaction between familial Amyotrophic Lateral Sclerosis (ALS)-linked SOD1 mutants and the dynein complex
-
DOI 10.1074/jbc.M609743200
-
Zhang F., Ström A. L., Fukada K., Lee S., Hayward L. J., Zhu H., Interaction between familial Amyotrophic Lateral Sclerosis (ALS)-linked SOD1 mutants and the dynein complex. Journal of Biological Chemistry 2007 282 22 16691 16699 2-s2.0-34447550238 10.1074/jbc.M609743200 (Pubitemid 47100405)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.22
, pp. 16691-16699
-
-
Zhang, F.1
Strom, A.-L.2
Fukada, K.3
Lee, S.4
Hayward, L.J.5
Zhu, H.6
-
147
-
-
0026613829
-
Ultrastructutal study of skein-like inclusions in anterior horn neurons of patients with motor neuron disease
-
2-s2.0-0026613829 10.1016/0304-3940(92)90575-R
-
Sasaki S., Maruyama S., Ultrastructutal study of skein-like inclusions in anterior horn neurons of patients with motor neuron disease. Neuroscience Letters 1992 147 2 121 124 2-s2.0-0026613829 10.1016/0304-3940(92)90575-R
-
(1992)
Neuroscience Letters
, vol.147
, Issue.2
, pp. 121-124
-
-
Sasaki, S.1
Maruyama, S.2
-
148
-
-
0028001606
-
Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis
-
Figlewicz D. A., Krizus A., Martinoli M. G., Meininger V., Dib M., Rouleau G. A., Julien J. P., Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis. Human Molecular Genetics 1994 3 10 1757 1761 2-s2.0-0028001606 (Pubitemid 24310467)
-
(1994)
Human Molecular Genetics
, vol.3
, Issue.10
, pp. 1757-1761
-
-
Figlewicz, D.A.1
Krizus, A.2
Martinoli, M.G.3
Meininger, V.4
Dib, M.5
Rouleau, G.A.6
Julien, J.-P.7
-
149
-
-
0029004898
-
Defective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosis
-
2-s2.0-0029004898
-
Collard J. F., Cote F., Julien J. P., Defective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosis. Nature 1995 375 6526 61 64 2-s2.0-0029004898
-
(1995)
Nature
, vol.375
, Issue.6526
, pp. 61-64
-
-
Collard, J.F.1
Cote, F.2
Julien, J.P.3
-
150
-
-
0029991827
-
Colocalization of NOS and SOD1 in neurofilament accumulation within motor neurons of amyotrophic lateral sclerosis: An immunohistochemical study
-
DOI 10.1016/0891-0618(96)00137-8
-
Chou S. M., Wang H. S., Komai K., Colocalization of NOS and SOD1 in neurofilament accumulation within motor neurons of amyotrophic lateral sclerosis: an immunohistochemical study. Journal of Chemical Neuroanatomy 1996 10 3-4 249 258 2-s2.0-0029991827 10.1016/0891-0618(96)00137-8 (Pubitemid 26196652)
-
(1996)
Journal of Chemical Neuroanatomy
, vol.10
, Issue.3-4
, pp. 249-258
-
-
Chou, S.M.1
Wang, H.S.2
Komai, K.3
-
151
-
-
67650727404
-
Oxidative stress induces parallel autophagy and mitochondria dysfunction in human glioma U251 cells
-
2-s2.0-67650727404 10.1093/toxsci/kfp101
-
Zhang H., Kong X., Kang J., Su J., Li Y., Zhong J., Sun L., Oxidative stress induces parallel autophagy and mitochondria dysfunction in human glioma U251 cells. Toxicological Sciences 2009 110 2 376 388 2-s2.0-67650727404 10.1093/toxsci/kfp101
-
(2009)
Toxicological Sciences
, vol.110
, Issue.2
, pp. 376-388
-
-
Zhang, H.1
Kong, X.2
Kang, J.3
Su, J.4
Li, Y.5
Zhong, J.6
Sun, L.7
-
152
-
-
84555195856
-
Autophagy, mitochondria and oxidative stress: Cross-talk and redox signalling
-
10.1042/BJ20111451
-
Lee J., Giordano S., Zhang J., Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling. Biochemical Journal 2012 441 523 540 10.1042/BJ20111451
-
(2012)
Biochemical Journal
, vol.441
, pp. 523-540
-
-
Lee, J.1
Giordano, S.2
Zhang, J.3
-
153
-
-
41449113885
-
Altered macroautophagy in the spinal cord of SOD1 mutant mice
-
Li A., Zhang X., Le W., Altered macroautophagy in the spinal cord of SOD1 mutant mice. Autophagy 2008 4 3 290 293 2-s2.0-41449113885 (Pubitemid 351458089)
-
(2008)
Autophagy
, vol.4
, Issue.3
, pp. 290-293
-
-
Li, A.1
Zhang, X.2
Le, W.3
-
154
-
-
64049113909
-
Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex
-
2-s2.0-64049113909 10.1038/ncb1854
-
Zhong Y., Wang Q. J., Li X., Yan Y., Backer J. M., Chait B. T., Heintz N., Yue Z., Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex. Nature Cell Biology 2009 11 4 468 476 2-s2.0-64049113909 10.1038/ncb1854
-
(2009)
Nature Cell Biology
, vol.11
, Issue.4
, pp. 468-476
-
-
Zhong, Y.1
Wang, Q.J.2
Li, X.3
Yan, Y.4
Backer, J.M.5
Chait, B.T.6
Heintz, N.7
Yue, Z.8
-
155
-
-
79955522014
-
Autophagy in spinal cord motor neurons in sporadic amyotrophic lateral sclerosis
-
2-s2.0-79955522014 10.1097/NEN.0b013e3182160690
-
Sasaki S., Autophagy in spinal cord motor neurons in sporadic amyotrophic lateral sclerosis. Journal of Neuropathology and Experimental Neurology 2011 70 5 349 359 2-s2.0-79955522014 10.1097/NEN.0b013e3182160690
-
(2011)
Journal of Neuropathology and Experimental Neurology
, vol.70
, Issue.5
, pp. 349-359
-
-
Sasaki, S.1
-
156
-
-
34548125010
-
Increased autophagy in transgenic mice with a G93A mutant SOD1 gene
-
DOI 10.1016/j.brainres.2007.06.045, PII S000689930701356X
-
Morimoto N., Nagai M., Ohta Y., Miyazaki K., Kurata T., Morimoto M., Murakami T., Takehisa Y., Ikeda Y., Kamiya T., Abe K., Increased autophagy in transgenic mice with a G93A mutant SOD1 gene. Brain Research 2007 1167 1 112 117 2-s2.0-34548125010 10.1016/j.brainres.2007.06.045 (Pubitemid 47302432)
-
(2007)
Brain Research
, vol.1167
, Issue.1
, pp. 112-117
-
-
Morimoto, N.1
Nagai, M.2
Ohta, Y.3
Miyazaki, K.4
Kurata, T.5
Morimoto, M.6
Murakami, T.7
Takehisa, Y.8
Ikeda, Y.9
Kamiya, T.10
Abe, K.11
-
157
-
-
43249109174
-
Endoplasmic reticulum stress responses
-
2-s2.0-43249109174 10.1007/s00018-007-7383-5
-
Schröder M., Endoplasmic reticulum stress responses. Cellular and Molecular Life Sciences 2008 65 6 862 894 2-s2.0-43249109174 10.1007/s00018-007-7383-5
-
(2008)
Cellular and Molecular Life Sciences
, vol.65
, Issue.6
, pp. 862-894
-
-
Schröder, M.1
-
158
-
-
33749563294
-
Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1
-
DOI 10.1074/jbc.M603393200
-
Atkin J. D., Farg M. A., Turner B. J., Tomas D., Lysaght J. A., Nunan J., Rembach A., Nagley P., Beart P. M., Cheema S. S., Horne M. K., Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1. Journal of Biological Chemistry 2006 281 40 30152 30165 2-s2.0-33749563294 10.1074/jbc.M603393200 (Pubitemid 44537023)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.40
, pp. 30152-30165
-
-
Atkin, J.D.1
Farg, M.A.2
Turner, B.J.3
Tomas, D.4
Lysaght, J.A.5
Nunan, J.6
Rembach, A.7
Nagley, P.8
Beart, P.M.9
Cheema, S.S.10
Horne, M.K.11
-
159
-
-
4444265582
-
Degradation of misfolded proteins prevents ER-derived oxidative stress and cell death
-
DOI 10.1016/j.molcel.2004.08.025, PII S1097276504005118
-
Haynes C. M., Titus E. A., Cooper A. A., Degradation of misfolded proteins prevents ER-derived oxidative stress and cell death. Molecular Cell 2004 15 5 767 776 2-s2.0-4444265582 10.1016/j.molcel.2004.08.025 (Pubitemid 39194906)
-
(2004)
Molecular Cell
, vol.15
, Issue.5
, pp. 767-776
-
-
Haynes, C.M.1
Titus, E.A.2
Cooper, A.A.3
-
160
-
-
66149156941
-
ER stress and unfolded protein response in amyotrophic lateral sclerosis
-
2-s2.0-66149156941 10.1007/s12035-009-8054-3
-
Kanekura K., Suzuki H., Aiso S., Matsuoka M., ER stress and unfolded protein response in amyotrophic lateral sclerosis. Molecular Neurobiology 2009 39 2 81 89 2-s2.0-66149156941 10.1007/s12035-009-8054-3
-
(2009)
Molecular Neurobiology
, vol.39
, Issue.2
, pp. 81-89
-
-
Kanekura, K.1
Suzuki, H.2
Aiso, S.3
Matsuoka, M.4
-
161
-
-
84866748196
-
Mutant FUS induces endoplasmic reticulum stress in amyotrophic lateral sclerosis and interacts with protein disulfide-isomerase
-
10.1016/j.neurobiolaging.2012.02.009
-
Farg M. A., Soo K. Y., Walker A. K., Pham H., Orian J., Horne M. K., Warraich S. T., Williams K. L., Blair I. P., Atkin J. D., Mutant FUS induces endoplasmic reticulum stress in amyotrophic lateral sclerosis and interacts with protein disulfide-isomerase. Neurobiology of Aging 2012 33 12 2855 2868 10.1016/j.neurobiolaging.2012.02.009
-
(2012)
Neurobiology of Aging
, vol.33
, Issue.12
, pp. 2855-2868
-
-
Farg, M.A.1
Soo, K.Y.2
Walker, A.K.3
Pham, H.4
Orian, J.5
Horne, M.K.6
Warraich, S.T.7
Williams, K.L.8
Blair, I.P.9
Atkin, J.D.10
-
162
-
-
36749067790
-
Oxidative and endoplasmic reticulum stress interplay in sporadic amyotrophic lateral sclerosis
-
DOI 10.1093/brain/awm190
-
Ilieva E. V., Ayala V., Jové M., Dalfó E., Cacabelos D., Povedano M., Bellmunt M. J., Ferrer I., Pamplona R., Portero-Otín M., Oxidative and endoplasmic reticulum stress interplay in sporadic amyotrophic lateral sclerosis. Brain 2007 130 12 3111 3123 2-s2.0-36749067790 10.1093/brain/awm190 (Pubitemid 350209064)
-
(2007)
Brain
, vol.130
, Issue.12
, pp. 3111-3123
-
-
Ilieva, E.V.1
Ayala, V.2
Jove, M.3
Dalfo, E.4
Cacabelos, D.5
Povedano, M.6
Bellmunt, M.J.7
Ferrer, I.8
Pamplona, R.9
Portero-Otin, M.10
-
163
-
-
35848957485
-
Endoplasmic reticulum stress and oxidative stress: A vicious cycle or a double-edged sword?
-
DOI 10.1089/ars.2007.1782
-
Malhotra J. D., Kaufman R. J., Endoplasmic reticulum stress and oxidative stress: a vicious cycle or a double-edged sword? Antioxidants and Redox Signaling 2007 9 12 2277 2293 2-s2.0-35848957485 10.1089/ars.2007.1782 (Pubitemid 350059010)
-
(2007)
Antioxidants and Redox Signaling
, vol.9
, Issue.12
, pp. 2277-2293
-
-
Malhotra, J.D.1
Kaufman, R.J.2
-
164
-
-
84875548942
-
Mechanisms of neuroprotection by protein disulphide isomerase in amyotrophic lateral sclerosis
-
317340 10.1155/2011/317340
-
Walker A. K., Atkin J. D., Mechanisms of neuroprotection by protein disulphide isomerase in amyotrophic lateral sclerosis. Neurology Research International 2011 2011 7 317340 10.1155/2011/317340
-
(2011)
Neurology Research International
, vol.2011
, pp. 7
-
-
Walker, A.K.1
Atkin, J.D.2
-
165
-
-
0027959156
-
Protein disulphide isomerase: Building bridges in protein folding
-
DOI 10.1016/0968-0004(94)90072-8
-
Freedman R. B., Hirst T. R., Tuite M. F., Protein disulphide isomerase: building bridges in protein folding. Trends in Biochemical Sciences 1994 19 8 331 336 2-s2.0-0027959156 10.1016/0968-0004(94)90072-8 (Pubitemid 24259985)
-
(1994)
Trends in Biochemical Sciences
, vol.19
, Issue.8
, pp. 331-336
-
-
Freedman, R.B.1
Hirst, T.R.2
Tuite, M.F.3
-
166
-
-
84864956245
-
Protein disulfide isomerases in neurodegeneration: From disease mechanisms to biomedical applications
-
10.1016/j.febslet.2012.07.023
-
Andreu C. I., Woehlbier U., Torres M., Hetz C., Protein disulfide isomerases in neurodegeneration: from disease mechanisms to biomedical applications. FEBS Letters 2012 586 18 2826 2834 10.1016/j.febslet.2012.07.023
-
(2012)
FEBS Letters
, vol.586
, Issue.18
, pp. 2826-2834
-
-
Andreu, C.I.1
Woehlbier, U.2
Torres, M.3
Hetz, C.4
-
167
-
-
84875499653
-
The human protein disulfide isomerase gene family
-
10.1186/1479-7364-6-1
-
Galligan J. J., Petersen D. R., The human protein disulfide isomerase gene family. Human Genomics 2012 6 1 1 15 10.1186/1479-7364-6-1
-
(2012)
Human Genomics
, vol.6
, Issue.1
, pp. 1-15
-
-
Galligan, J.J.1
Petersen, D.R.2
-
168
-
-
14044271131
-
The human protein disulphide isomerase family: Substrate interactions and functional properties
-
DOI 10.1038/sj.embor.7400311
-
Ellgaard L., Ruddock L. W., The human protein disulphide isomerase family: substrate interactions and functional properties. EMBO Reports 2005 6 1 28 32 2-s2.0-14044271131 10.1038/sj.embor.7400311 (Pubitemid 41710070)
-
(2005)
EMBO Reports
, vol.6
, Issue.1
, pp. 28-32
-
-
Ellgaard, L.1
Ruddock, L.W.2
-
170
-
-
0034467411
-
Redox regulation by thioredoxin superfamily; protection against oxidative stress and aging
-
Tanaka T., Nakamura H., Nishiyama A., Hosoi F., Masutani H., Wada H., Yodoi J., Redox regulation by thioredoxin superfamily; protection against oxidative stress and aging. Free Radical Research 2000 33 6 851 855 2-s2.0-0034467411 (Pubitemid 32208492)
-
(2000)
Free Radical Research
, vol.33
, Issue.6
, pp. 851-855
-
-
Tanaka, T.1
Nakamura, H.2
Nishiyama, A.3
Hosoi, F.4
Masutani, H.5
Wada, H.6
Yodoi, J.7
-
171
-
-
0036836665
-
Proteins of the PDI family: Unpredicted non-ER locations and functions
-
2-s2.0-0036836665 10.1002/jcp.10172
-
Turano C., Coppari S., Altieri F., Ferraro A., Proteins of the PDI family: unpredicted non-ER locations and functions. Journal of Cellular Physiology 2002 193 2 154 163 2-s2.0-0036836665 10.1002/jcp.10172
-
(2002)
Journal of Cellular Physiology
, vol.193
, Issue.2
, pp. 154-163
-
-
Turano, C.1
Coppari, S.2
Altieri, F.3
Ferraro, A.4
-
172
-
-
2442761708
-
The protein disulphide-isomerase family: Unravelling a string of folds
-
DOI 10.1042/0264-6021:3390001
-
Ferrari D. M., Söling H. D., The protein disulphide-isomerase family: unravelling a string of folds. Biochemical Journal 1999 339 1 1 10 2-s2.0-2442761708 10.1042/0264-6021:3390001 (Pubitemid 29179283)
-
(1999)
Biochemical Journal
, vol.339
, Issue.1
, pp. 1-10
-
-
Ferrari, D.M.1
Soling, H.-D.2
-
173
-
-
30344444015
-
The crystal structure of yeast protein disulfide isomerase suggests cooperativity between its active sites
-
DOI 10.1016/j.cell.2005.10.044, PII S0092867405014121
-
Tian G., Xiang S., Noiva R., Lennarz W. J., Schindelin H., The crystal structure of yeast protein disulfide isomerase suggests cooperativity between its active sites. Cell 2006 124 1 61 73 10.1016/j.cell.2005.10.044 (Pubitemid 43069310)
-
(2006)
Cell
, vol.124
, Issue.1
, pp. 61-73
-
-
Tian, G.1
Xiang, S.2
Noiva, R.3
Lennarz, W.J.4
Schindelin, H.5
-
174
-
-
0032481380
-
The b' domain provides the principal peptide-binding site of protein disulfide isomerase but all domains contribute to binding of misfolded proteins
-
DOI 10.1093/emboj/17.4.927
-
Klappa P., Ruddock L. W., Darby N. J., Freedman R. B., The b' domain provides the principal peptide-binding site of protein disulfide isomerase but all domains contribute to binding of misfolded proteins. EMBO Journal 1998 17 4 927 935 2-s2.0-0032481380 10.1093/emboj/17.4.927 (Pubitemid 28077647)
-
(1998)
EMBO Journal
, vol.17
, Issue.4
, pp. 927-935
-
-
Klappa, P.1
Ruddock, L.W.2
Darby, N.J.3
Freedman, R.B.4
-
175
-
-
12144288546
-
Molecular Characterization of the Principal Substrate Binding Site of the Ubiquitous Folding Catalyst Protein Disulfide Isomerase
-
DOI 10.1074/jbc.M312193200
-
Pirneskoski A., Klappa P., Lobell M., Williamson R. A., Byrne L., Alanen H. I., Salo K. E. H., Kivirikko K. I., Freedman R. B., Ruddock L. W., Molecular characterization of the principal substrate binding site of the ubiquitous folding catalyst protein disulfide isomerase. Journal of Biological Chemistry 2004 279 11 10374 10381 2-s2.0-12144288546 10.1074/jbc.M312193200 (Pubitemid 38372645)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.11
, pp. 10374-10381
-
-
Pirneskoski, A.1
Klappa, P.2
Lobell, M.3
Williamson, R.A.4
Byrne, L.5
Alanen, H.I.6
Salo, K.E.H.7
Kivirikko, K.I.8
Freedman, R.B.9
Ruddock, L.W.10
-
176
-
-
77956625219
-
A structural overview of the PDI family of proteins
-
2-s2.0-77956625219 10.1111/j.1742-4658.2010.07793.x
-
Kozlov G., Määttänen P., Thomas D. Y., Gehring K., A structural overview of the PDI family of proteins. FEBS Journal 2010 277 19 3924 3936 2-s2.0-77956625219 10.1111/j.1742-4658.2010.07793.x
-
(2010)
FEBS Journal
, vol.277
, Issue.19
, pp. 3924-3936
-
-
Kozlov, G.1
Määttänen, P.2
Thomas, D.Y.3
Gehring, K.4
-
177
-
-
0030836862
-
A mutant truncated protein disulfide isomerase with no chaperone activity
-
DOI 10.1074/jbc.272.44.27572
-
Dai Y., Wang C. C., A mutant truncated protein disulfide isomerase with no chaperone activity. Journal of Biological Chemistry 1997 272 44 27572 27576 2-s2.0-0030836862 10.1074/jbc.272.44.27572 (Pubitemid 27473548)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.44
, pp. 27572-27576
-
-
Dai, Y.1
Wang, C.-C.2
-
178
-
-
70849101711
-
Protein disulphide isomerase family members show distinct substrate specificity: P5 is targeted to BiP client proteins
-
2-s2.0-70849101711 10.1242/jcs.059154
-
Jessop C. E., Watkins R. H., Simmons J. J., Tasab M., Bulleid N. J., Protein disulphide isomerase family members show distinct substrate specificity: P5 is targeted to BiP client proteins. Journal of Cell Science 2009 122 23 4287 4295 2-s2.0-70849101711 10.1242/jcs.059154
-
(2009)
Journal of Cell Science
, vol.122
, Issue.23
, pp. 4287-4295
-
-
Jessop, C.E.1
Watkins, R.H.2
Simmons, J.J.3
Tasab, M.4
Bulleid, N.J.5
-
179
-
-
77957806157
-
Disulphide production by Ero1 α -PDI relay is rapid and effectively regulated
-
2-s2.0-77957806157 10.1038/emboj.2010.203
-
Appenzeller-Herzog C., Riemer J., Zito E., Chin K. T., Ron D., Spiess M., Ellgaard L., Disulphide production by Ero1 α -PDI relay is rapid and effectively regulated. EMBO Journal 2010 29 19 3318 3329 2-s2.0-77957806157 10.1038/emboj.2010.203
-
(2010)
EMBO Journal
, vol.29
, Issue.19
, pp. 3318-3329
-
-
Appenzeller-Herzog, C.1
Riemer, J.2
Zito, E.3
Chin, K.T.4
Ron, D.5
Spiess, M.6
Ellgaard, L.7
-
180
-
-
71549132149
-
Protein disulfide isomerase: A critical evaluation of its function in disulfide bond formation
-
2-s2.0-71549132149 10.1089/ars.2009.2466
-
Hatahet F., Ruddock L. W., Protein disulfide isomerase: a critical evaluation of its function in disulfide bond formation. Antioxidants and Redox Signaling 2009 11 11 2807 2850 2-s2.0-71549132149 10.1089/ars.2009.2466
-
(2009)
Antioxidants and Redox Signaling
, vol.11
, Issue.11
, pp. 2807-2850
-
-
Hatahet, F.1
Ruddock, L.W.2
-
181
-
-
80052372197
-
Multiple ways to make disulfides
-
2-s2.0-79960339720 10.1016/j.tibs.2011.05.004
-
Bulleid N. J., Ellgaard L., Multiple ways to make disulfides. Trends in Biochemical Sciences 2011 2-s2.0-79960339720 10.1016/j.tibs.2011.05.004
-
(2011)
Trends in Biochemical Sciences
-
-
Bulleid, N.J.1
Ellgaard, L.2
-
182
-
-
33645784167
-
The role of glutathione in disulphide bond formation and endoplasmic-reticulum-generated oxidative stress
-
2-s2.0-33645784167 10.1038/sj.embor.7400645
-
Chakravarthi S., Jessop C. E., Bulleid N. J., The role of glutathione in disulphide bond formation and endoplasmic-reticulum-generated oxidative stress. EMBO Reports 2006 7 3 271 275 2-s2.0-33645784167 10.1038/sj.embor.7400645
-
(2006)
EMBO Reports
, vol.7
, Issue.3
, pp. 271-275
-
-
Chakravarthi, S.1
Jessop, C.E.2
Bulleid, N.J.3
-
183
-
-
0027293791
-
Determination of the reduction-oxidation potential of the thioredoxin- like domains of protein disulfide-isomerase from the equilibrium with glutathione and thioredoxin
-
Lundström J., Holmgren A., Determination of the reduction-oxidation potential of the thioredoxin-like domains of protein disulfide-isomerase from the equilibrium with glutathione and thioredoxin. Biochemistry 1993 32 26 6649 6655 2-s2.0-0027293791 (Pubitemid 23217134)
-
(1993)
Biochemistry
, vol.32
, Issue.26
, pp. 6649-6655
-
-
Lundstrom, J.1
Holmgren, A.2
-
184
-
-
31044452359
-
Generating disulfides enzymatically: Reaction products and electron acceptors of the endoplasmic reticulum thiol oxidase Ero1p
-
DOI 10.1073/pnas.0506448103
-
Gross E., Sevier C. S., Heldman N., Vitu E., Bentzur M., Kaiser C. A., Thorpe C., Fass D., Generating disulfides enzymatically: reaction products and electron acceptors of the endoplasmic reticulum thiol oxidase Ero1p. Proceedings of the National Academy of Sciences of the United States of America 2006 103 2 299 304 2-s2.0-31044452359 10.1073/pnas.0506448103 (Pubitemid 43122395)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.2
, pp. 299-304
-
-
Gross, E.1
Sevier, C.S.2
Heldman, N.3
Vitu, E.4
Bentzur, M.5
Kaiser, C.A.6
Thorpe, C.7
Fass, D.8
-
185
-
-
56349087407
-
Real-time redox measurements during endoplasmic reticulum stress reveal interlinked protein folding functions
-
2-s2.0-56349087407 10.1016/j.cell.2008.10.011
-
Merksamer P. I., Trusina A., Papa F. R., Real-time redox measurements during endoplasmic reticulum stress reveal interlinked protein folding functions. Cell 2008 135 5 933 947 2-s2.0-56349087407 10.1016/j.cell.2008.10.011
-
(2008)
Cell
, vol.135
, Issue.5
, pp. 933-947
-
-
Merksamer, P.I.1
Trusina, A.2
Papa, F.R.3
-
186
-
-
0033163758
-
Competition between glutathione and protein thiols for disulphide-bond formation
-
Cuozzo J. W., Kaiser C. A., Competition between glutathione and protein thiols for disulphide-bond formation. Nature Cell Biology 1999 1 3 130 135 2-s2.0-0033163758 (Pubitemid 129656016)
-
(1999)
Nature Cell Biology
, vol.1
, Issue.3
, pp. 130-135
-
-
Cuozzo, J.W.1
Kaiser, C.A.2
-
187
-
-
77956684691
-
Functional relationship between protein disulfide isomerase family members during the oxidative folding of human secretory proteins
-
2-s2.0-77956684691 10.1091/mbc.E10-04-0356
-
Rutkevich L. A., Cohen-Doyle M. F., Brockmeier U., Williams D. B., Functional relationship between protein disulfide isomerase family members during the oxidative folding of human secretory proteins. Molecular Biology of the Cell 2010 21 18 3093 3105 2-s2.0-77956684691 10.1091/mbc.E10-04-0356
-
(2010)
Molecular Biology of the Cell
, vol.21
, Issue.18
, pp. 3093-3105
-
-
Rutkevich, L.A.1
Cohen-Doyle, M.F.2
Brockmeier, U.3
Williams, D.B.4
-
188
-
-
80055031464
-
Protein disulfide isomerase-immunopositive inclusions in patients with amyotrophic lateral sclerosis
-
10.3109/17482968.2011.594055
-
Honjo Y., Kaneko S., Ito H., Horibe T., Nagashima M., Nakamura M., Fujita K., Takahashi R., Kusaka H., Kawakami K., Protein disulfide isomerase-immunopositive inclusions in patients with amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis 2011 12 6 444 450 10.3109/17482968. 2011.594055
-
(2011)
Amyotrophic Lateral Sclerosis
, vol.12
, Issue.6
, pp. 444-450
-
-
Honjo, Y.1
Kaneko, S.2
Ito, H.3
Horibe, T.4
Nagashima, M.5
Nakamura, M.6
Fujita, K.7
Takahashi, R.8
Kusaka, H.9
Kawakami, K.10
-
189
-
-
43449099127
-
The Amyotrophic Lateral Sclerosis 8 Protein VAPB Is Cleaved, Secreted, and Acts as a Ligand for Eph Receptors
-
DOI 10.1016/j.cell.2008.04.039, PII S0092867408006132
-
Tsuda H., Han S. M., Yang Y., Tong C., Lin Y. Q., Mohan K., Haueter C., Zoghbi A., Harati Y., Kwan J., Miller M. A., Bellen H. J., The amyotrophic lateral sclerosis 8 protein VAPB is cleaved, secreted, and acts as a ligand for Eph receptors. Cell 2008 133 6 963 977 2-s2.0-43449099127 10.1016/j.cell.2008. 04.039 (Pubitemid 351787741)
-
(2008)
Cell
, vol.133
, Issue.6
, pp. 963-977
-
-
Tsuda, H.1
Han, S.M.2
Yang, Y.3
Tong, C.4
Lin, Y.Q.5
Mohan, K.6
Haueter, C.7
Zoghbi, A.8
Harati, Y.9
Kwan, J.10
Miller, M.A.11
Bellen, H.J.12
-
190
-
-
70350218853
-
Nitrosative stress-induced S-glutathionylation of protein disulfide isomerase leads to activation of the unfolded protein response
-
2-s2.0-70350218853 10.1158/0008-5472.CAN-09-0493
-
Townsend D. M., Manevich Y., Lin H., Ying X., Bowers R. R., Hutchens S., Tew K. D., Nitrosative stress-induced S-glutathionylation of protein disulfide isomerase leads to activation of the unfolded protein response. Cancer Research 2009 69 19 7626 7634 2-s2.0-70350218853 10.1158/0008-5472.CAN-09-0493
-
(2009)
Cancer Research
, vol.69
, Issue.19
, pp. 7626-7634
-
-
Townsend, D.M.1
Manevich, Y.2
Lin, H.3
Ying, X.4
Bowers, R.R.5
Hutchens, S.6
Tew, K.D.7
-
191
-
-
33745315287
-
S-Nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration
-
DOI 10.1038/nature04782, PII NATURE04782
-
Uehara T., Nakamura T., Yao D., Shi Z. Q., Gu Z., Ma Y., Masliah E., Nomura Y., Lipton S. A., S-Nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration. Nature 2006 441 7092 513 517 2-s2.0-33745315287 10.1038/nature04782 (Pubitemid 44050153)
-
(2006)
Nature
, vol.441
, Issue.7092
, pp. 513-517
-
-
Uehara, T.1
Nakamura, T.2
Yao, D.3
Shi, Z.-Q.4
Gu, Z.5
Ma, Y.6
Masliah, E.7
Nomura, Y.8
Lipton, S.A.9
-
192
-
-
84870953719
-
S-nitrosylated protein disulphide isomerase contributes to mutant SOD1 aggregates in amyotrophic lateral sclerosis
-
10.1111/jnc.12046
-
Chen X., Li C., Guan T., Shang H., Cui L., Li X. M., Kong J., S-nitrosylated protein disulphide isomerase contributes to mutant SOD1 aggregates in amyotrophic lateral sclerosis. Journal of Neurochemistry 2012 124 1 45 58 10.1111/jnc.12046
-
(2012)
Journal of Neurochemistry
, vol.124
, Issue.1
, pp. 45-58
-
-
Chen, X.1
Li, C.2
Guan, T.3
Shang, H.4
Cui, L.5
Li, X.M.6
Kong, J.7
-
193
-
-
0030273704
-
Therapeutic horizons for amyotrophic lateral sclerosis
-
DOI 10.1016/S0959-4388(96)80103-6
-
Rothstein J. D., Therapeutic horizons for amyotrophic lateral sclerosis. Current Opinion in Neurobiology 1996 6 5 679 687 2-s2.0-0030273704 10.1016/S0959-4388(96)80103-6 (Pubitemid 26387725)
-
(1996)
Current Opinion in Neurobiology
, vol.6
, Issue.5
, pp. 679-687
-
-
Rothstein, J.D.1
-
194
-
-
0029995017
-
Neuronal growth and death: Order and disorder in the axoplasm
-
DOI 10.1016/S0092-8674(00)81044-2
-
Cleveland D. W., Neuronal growth and death: order and disorder in the axoplasm. Cell 1996 84 5 663 666 2-s2.0-0029995017 10.1016/S0092-8674(00)81044-2 (Pubitemid 26094196)
-
(1996)
Cell
, vol.84
, Issue.5
, pp. 663-666
-
-
Cleveland, D.W.1
|