Ultrastructural study of synapses in the anterior horn neurons of patients with amyotrophic lateral sclerosis

Neuroscience Letters

Volumn 204, Issue 1-2, 1996, Pages 53-56

  Sasaki, Shoichi ^a   Iwata, Makoto ^a  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

Amyotrophic lateral sclerosis; Anterior horn cell; Degenerative changes; Synapse; Ultrastructure

Indexed keywords

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; MALE; NERVE DEGENERATION; PRIORITY JOURNAL; SPINAL CORD VENTRAL HORN; SYNAPSE; ULTRASTRUCTURE;

EID: 0030019414     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3940(96)12314-4     Document Type: Article

References (12)

1. Chen, D.H., Qualitative and quantitative study of synaptic displacement in chromatolyzed spinal motoneurons of the cat, J. Comp. Neurol., 177 (1978) 635-664.
2. Eccles, J.C., Libert, B. and Young, R.R., The behavior of chromatolyzed motoneurons studied by intracellular recording, J. Physiol., 143 (1958)11-40.
3. Gray, E.G. and Hamlyn, L.H., Electron microscopy of experimental degeneration in the avian optic tectum, J. Anat. London, 96 (1962) 309-316.
4. Heimer, L., Descending supraspinal pathways. In The Human Brain and Spinal Cord. Functional Neuroanatomy and Dissection Guide, Springer-Verlag, New York, 1982, pp. 187-192.
5. Ibara, Y., Desiraju, T. and Pappas, G.D., Light and electron microscopic study of the projection of the medial septal nucleus to the hippocampus of the cat, Exp. Neurol., 33 (1971) 103-122.
6. Ikemoto, A., Kawanami, T., Llena, J.F. and Hirano, A., Immunocytochemical studies on synaptophysin in the anterior horn of lower motor neuron disease, J. Neuropathol. Exp. Neurol., 53 (1994) 196-201.
7. Kuno, M. and Llinas, R., Alterations of synaptic action in chromatolyzed motoneurons of the cat, J. Physiol., 210 (1970) 823-838.
8. Laatsch, R.H. and Cowan, W.M., Electron microscopic studies of the dentate gyrus of the rat. II. Degeneration of commissural afferents, J. Comp. Neurol., 130 (1967) 241-262.
9. Matsumoto, S., Goto, S., Kusaka, H., Ito, H. and Imai, T., Synaptic pathology of spinal anterior horn cells in amyotrophic lateral sclerosis: an imrmmohistochemical study, J. Neurol. Sci., 125 (1994) 180-185.
10. Sasaki, S. and Maruyama, S., Decreased synaptophysin immunoreactivity of the anterior horns in motor neuron disease, Acta Neuropathol., 87 (1994) 125-128.
11. Sasaki, S. and Maruyama, S., Synapse loss in anterior horn neurons in amyotrophic lateral sclerosis, Acta Neuropathol., 88 (1994) 222-227.
12. Sterman, A.B. and Sposito, N., Motoneuron axosomatic synapses are altered in axonopathy, J. Neuropathol. Exp. Neurol., 43 (1984) 201-209.