-
1
-
-
79953762174
-
Unraveling the biological roles of reactive oxygen species
-
Murphy M.P., Holmgren A., Larsson N.G., Halliwell B., Chang C.J., Kalyanaraman B., et al. Unraveling the biological roles of reactive oxygen species. Cell Metabolism 2011, 13:361-366.
-
(2011)
Cell Metabolism
, vol.13
, pp. 361-366
-
-
Murphy, M.P.1
Holmgren, A.2
Larsson, N.G.3
Halliwell, B.4
Chang, C.J.5
Kalyanaraman, B.6
-
2
-
-
79960286223
-
Signal transduction by reactive oxygen species
-
Finkel T. Signal transduction by reactive oxygen species. The Journal of Cell Biology 2011, 194:7-15.
-
(2011)
The Journal of Cell Biology
, vol.194
, pp. 7-15
-
-
Finkel, T.1
-
3
-
-
45049085873
-
Redox-based regulation of signal transduction: principles, pitfalls, and promises
-
Janssen-Heininger Y.M., Mossman B.T., Heintz N.H., Forman H.J., Kalyanaraman B., Finkel T., et al. Redox-based regulation of signal transduction: principles, pitfalls, and promises. Free Radical Biology & Medicine 2008, 45:1-17.
-
(2008)
Free Radical Biology & Medicine
, vol.45
, pp. 1-17
-
-
Janssen-Heininger, Y.M.1
Mossman, B.T.2
Heintz, N.H.3
Forman, H.J.4
Kalyanaraman, B.5
Finkel, T.6
-
4
-
-
84856729192
-
Mitochondrial thiols in antioxidant protection and redox signaling: distinct roles for glutathionylation and other thiol modifications
-
Murphy M.P. Mitochondrial thiols in antioxidant protection and redox signaling: distinct roles for glutathionylation and other thiol modifications. Antioxidants and Redox Signalling 2012, 16:476-495.
-
(2012)
Antioxidants and Redox Signalling
, vol.16
, pp. 476-495
-
-
Murphy, M.P.1
-
5
-
-
33745631769
-
2, a necessary evil for cell signaling
-
2, a necessary evil for cell signaling. Science 2006, 312:1882-1883.
-
(2006)
Science
, vol.312
, pp. 1882-1883
-
-
Rhee, S.G.1
-
6
-
-
77956634584
-
Targeting the reversibly oxidized protein tyrosine phosphatase superfamily
-
Boivin B., Yang M., Tonks N.K. Targeting the reversibly oxidized protein tyrosine phosphatase superfamily. Science Signaling 2010, 3:pl2.
-
(2010)
Science Signaling
, vol.3
-
-
Boivin, B.1
Yang, M.2
Tonks, N.K.3
-
7
-
-
33846794822
-
The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology
-
Bedard K., Krause K.H. The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiological Reviews 2007, 87:245-313.
-
(2007)
Physiological Reviews
, vol.87
, pp. 245-313
-
-
Bedard, K.1
Krause, K.H.2
-
8
-
-
1542406446
-
NOX enzymes and the biology of reactive oxygen
-
Lambeth J.D. NOX enzymes and the biology of reactive oxygen. Nature Reviews: Immunology 2004, 4:181-189.
-
(2004)
Nature Reviews: Immunology
, vol.4
, pp. 181-189
-
-
Lambeth, J.D.1
-
9
-
-
77956879800
-
Hematologically important mutations: X-linked chronic granulomatous disease (third update)
-
Roos D., Kuhns D.B., Maddalena A., Roesler J., Lopez J.A., Ariga T., et al. Hematologically important mutations: X-linked chronic granulomatous disease (third update). Blood Cells, Molecules, and Diseases 2010, 45:246-265.
-
(2010)
Blood Cells, Molecules, and Diseases
, vol.45
, pp. 246-265
-
-
Roos, D.1
Kuhns, D.B.2
Maddalena, A.3
Roesler, J.4
Lopez, J.A.5
Ariga, T.6
-
10
-
-
80053030745
-
Shedding of the Mer tyrosine kinase receptor is mediated by ADAM17 protein through a pathway involving reactive oxygen species, protein kinase Cdelta, and p38 mitogen-activated protein kinase (MAPK)
-
Thorp E., Vaisar T., Subramanian M., Mautner L., Blobel C., Tabas I. Shedding of the Mer tyrosine kinase receptor is mediated by ADAM17 protein through a pathway involving reactive oxygen species, protein kinase Cdelta, and p38 mitogen-activated protein kinase (MAPK). Journal of Biological Chemistry 2011, 286:33335-33344.
-
(2011)
Journal of Biological Chemistry
, vol.286
, pp. 33335-33344
-
-
Thorp, E.1
Vaisar, T.2
Subramanian, M.3
Mautner, L.4
Blobel, C.5
Tabas, I.6
-
11
-
-
65349141906
-
Endosomal Nox2 facilitates redox-dependent induction of NF-kappaB by TNF-alpha
-
Li Q., Spencer N.Y., Oakley F.D., Buettner G.R., Engelhardt J.F. Endosomal Nox2 facilitates redox-dependent induction of NF-kappaB by TNF-alpha. Antioxidants and Redox Signalling 2009, 11:1249-1263.
-
(2009)
Antioxidants and Redox Signalling
, vol.11
, pp. 1249-1263
-
-
Li, Q.1
Spencer, N.Y.2
Oakley, F.D.3
Buettner, G.R.4
Engelhardt, J.F.5
-
12
-
-
79955604490
-
Genetic ablation of phagocytic NADPH oxidase in mice limits TNFalpha-induced inflammation in the lungs but not other tissues
-
Zhang W.J., Wei H., Tien Y.T., Frei B. Genetic ablation of phagocytic NADPH oxidase in mice limits TNFalpha-induced inflammation in the lungs but not other tissues. Free Radical Biology and Medicine 2011, 50:1517-1525.
-
(2011)
Free Radical Biology and Medicine
, vol.50
, pp. 1517-1525
-
-
Zhang, W.J.1
Wei, H.2
Tien, Y.T.3
Frei, B.4
-
13
-
-
69349088255
-
Riboflavin kinase couples TNF receptor 1 to NADPH oxidase
-
Yazdanpanah B., Wiegmann K., Tchikov V., Krut O., Pongratz C., Schramm M., et al. Riboflavin kinase couples TNF receptor 1 to NADPH oxidase. Nature 2009, 460:1159-1163.
-
(2009)
Nature
, vol.460
, pp. 1159-1163
-
-
Yazdanpanah, B.1
Wiegmann, K.2
Tchikov, V.3
Krut, O.4
Pongratz, C.5
Schramm, M.6
-
14
-
-
0028893203
-
Mouse model of X-linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production
-
Pollock J.D., Williams D.A., Gifford M.A., Li L.L., Du X., Fisherman J., et al. Mouse model of X-linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production. Nature Genetics 1995, 9:202-209.
-
(1995)
Nature Genetics
, vol.9
, pp. 202-209
-
-
Pollock, J.D.1
Williams, D.A.2
Gifford, M.A.3
Li, L.L.4
Du, X.5
Fisherman, J.6
-
15
-
-
79959333447
-
Spontaneous and aging-dependent development of arthritis in NADPH oxidase 2 deficiency through altered differentiation of CD11b+ and Th/Treg cells
-
Lee K., Won H.Y., Bae M.A., Hong J.H., Hwang E.S. Spontaneous and aging-dependent development of arthritis in NADPH oxidase 2 deficiency through altered differentiation of CD11b+ and Th/Treg cells. Proceedings of the National Academy of Sciences of the United States of America 2011, 108:9548-9553.
-
(2011)
Proceedings of the National Academy of Sciences of the United States of America
, vol.108
, pp. 9548-9553
-
-
Lee, K.1
Won, H.Y.2
Bae, M.A.3
Hong, J.H.4
Hwang, E.S.5
-
16
-
-
0141648399
-
Deficiency of NADPH oxidase components p47phox and gp91phox caused granulomatous synovitis and increased connective tissue destruction in experimental arthritis models
-
van de Loo F.A., Bennink M.B., Arntz O.J., Smeets R.L., Lubberts E., Joosten L.A., et al. Deficiency of NADPH oxidase components p47phox and gp91phox caused granulomatous synovitis and increased connective tissue destruction in experimental arthritis models. American Journal of Pathology 2003, 163:1525-1537.
-
(2003)
American Journal of Pathology
, vol.163
, pp. 1525-1537
-
-
van de Loo, F.A.1
Bennink, M.B.2
Arntz, O.J.3
Smeets, R.L.4
Lubberts, E.5
Joosten, L.A.6
-
17
-
-
4344591766
-
Enhanced autoimmunity, arthritis, and encephalomyelitis in mice with a reduced oxidative burst due to a mutation in the Ncf1 gene
-
Hultqvist M., Olofsson P., Holmberg J., Backstrom B.T., Tordsson J., Holmdahl R. Enhanced autoimmunity, arthritis, and encephalomyelitis in mice with a reduced oxidative burst due to a mutation in the Ncf1 gene. Proceedings of the National Academy of Sciences of the United States of America 2004, 101:12646-12651.
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, pp. 12646-12651
-
-
Hultqvist, M.1
Olofsson, P.2
Holmberg, J.3
Backstrom, B.T.4
Tordsson, J.5
Holmdahl, R.6
-
18
-
-
77649260429
-
Reactive oxygen species-independent activation of the IL-1beta inflammasome in cells from patients with chronic granulomatous disease
-
van de Veerdonk F.L., Smeekens S.P., Joosten L.A., Kullberg B.J., Dinarello C.A., van der Meer J.W., et al. Reactive oxygen species-independent activation of the IL-1beta inflammasome in cells from patients with chronic granulomatous disease. Proceedings of the National Academy of Sciences of the United States of America 2010, 107:3030-3033.
-
(2010)
Proceedings of the National Academy of Sciences of the United States of America
, vol.107
, pp. 3030-3033
-
-
van de Veerdonk, F.L.1
Smeekens, S.P.2
Joosten, L.A.3
Kullberg, B.J.4
Dinarello, C.A.5
van der Meer, J.W.6
-
19
-
-
77952634453
-
NADPH oxidase 1 modulates WNT and NOTCH1 signaling to control the fate of proliferative progenitor cells in the colon
-
Coant N., Ben Mkaddem S., Pedruzzi E., Guichard C., Treton X., Ducroc R., et al. NADPH oxidase 1 modulates WNT and NOTCH1 signaling to control the fate of proliferative progenitor cells in the colon. Molecular and Cellular Biology 2010, 30:2636-2650.
-
(2010)
Molecular and Cellular Biology
, vol.30
, pp. 2636-2650
-
-
Coant, N.1
Ben Mkaddem, S.2
Pedruzzi, E.3
Guichard, C.4
Treton, X.5
Ducroc, R.6
-
20
-
-
77951631927
-
Proinflammatory cytokine IL-1beta stimulates IL-8 synthesis in mast cells via a leukotriene B4 receptor 2-linked pathway, contributing to angiogenesis
-
Kim G.Y., Lee J.W., Ryu H.C., Wei J.D., Seong C.M., Kim J.H. Proinflammatory cytokine IL-1beta stimulates IL-8 synthesis in mast cells via a leukotriene B4 receptor 2-linked pathway, contributing to angiogenesis. Journal of Immunology 2010, 184:3946-3954.
-
(2010)
Journal of Immunology
, vol.184
, pp. 3946-3954
-
-
Kim, G.Y.1
Lee, J.W.2
Ryu, H.C.3
Wei, J.D.4
Seong, C.M.5
Kim, J.H.6
-
21
-
-
58149343341
-
Reactive oxygen species derived from NOX1/NADPH oxidase enhance inflammatory pain
-
Ibi M., Matsuno K., Shiba D., Katsuyama M., Iwata K., Kakehi T., et al. Reactive oxygen species derived from NOX1/NADPH oxidase enhance inflammatory pain. Journal of Neuroscience 2008, 28:9486-9494.
-
(2008)
Journal of Neuroscience
, vol.28
, pp. 9486-9494
-
-
Ibi, M.1
Matsuno, K.2
Shiba, D.3
Katsuyama, M.4
Iwata, K.5
Kakehi, T.6
-
22
-
-
34249820757
-
TNF-induced activation of the Nox1 NADPH oxidase and its role in the induction of necrotic cell death
-
Kim Y.S., Morgan M.J., Choksi S., Liu Z.G. TNF-induced activation of the Nox1 NADPH oxidase and its role in the induction of necrotic cell death. Molecular Cell 2007, 26:675-687.
-
(2007)
Molecular Cell
, vol.26
, pp. 675-687
-
-
Kim, Y.S.1
Morgan, M.J.2
Choksi, S.3
Liu, Z.G.4
-
23
-
-
67349208391
-
A role for NADPH oxidase 4 in the activation of vascular endothelial cells by oxidized phospholipids
-
Lee S., Gharavi N.M., Honda H., Chang I., Kim B., Jen N., et al. A role for NADPH oxidase 4 in the activation of vascular endothelial cells by oxidized phospholipids. Free Radical Biology and Medicine 2009, 47:145-151.
-
(2009)
Free Radical Biology and Medicine
, vol.47
, pp. 145-151
-
-
Lee, S.1
Gharavi, N.M.2
Honda, H.3
Chang, I.4
Kim, B.5
Jen, N.6
-
24
-
-
84855604126
-
LPS induced inflammatory responses in human peripheral blood mononuclear cells is mediated through NOX4 and Gialpha dependent PI-3kinase signalling
-
Ngkelo A., Meja K., Yeadon M., Adcock I., Kirkham P.A. LPS induced inflammatory responses in human peripheral blood mononuclear cells is mediated through NOX4 and Gialpha dependent PI-3kinase signalling. Journal of Inflammation (London) 2012, 9:1.
-
(2012)
Journal of Inflammation (London)
, vol.9
, pp. 1
-
-
Ngkelo, A.1
Meja, K.2
Yeadon, M.3
Adcock, I.4
Kirkham, P.A.5
-
25
-
-
49449116792
-
Oxidative innate immune defenses by Nox/Duox family NADPH oxidases
-
Rada B., Leto T.L. Oxidative innate immune defenses by Nox/Duox family NADPH oxidases. Contributions to Microbiology 2008, 15:164-187.
-
(2008)
Contributions to Microbiology
, vol.15
, pp. 164-187
-
-
Rada, B.1
Leto, T.L.2
-
26
-
-
14044249491
-
Expression and localization of NOX2 and NOX4 in primary human endothelial cells
-
Van Buul J.D., Fernandez-Borja M., Anthony E.C., Hordijk P.L. Expression and localization of NOX2 and NOX4 in primary human endothelial cells. Antioxidants and Redox Signalling 2005, 7:308-317.
-
(2005)
Antioxidants and Redox Signalling
, vol.7
, pp. 308-317
-
-
Van Buul, J.D.1
Fernandez-Borja, M.2
Anthony, E.C.3
Hordijk, P.L.4
-
27
-
-
77951281040
-
Upregulation of Nox4 by hypertrophic stimuli promotes apoptosis and mitochondrial dysfunction in cardiac myocytes
-
Ago T., Kuroda J., Pain J., Fu C., Li H., Sadoshima J. Upregulation of Nox4 by hypertrophic stimuli promotes apoptosis and mitochondrial dysfunction in cardiac myocytes. Circulation Research 2010, 106:1253-1264.
-
(2010)
Circulation Research
, vol.106
, pp. 1253-1264
-
-
Ago, T.1
Kuroda, J.2
Pain, J.3
Fu, C.4
Li, H.5
Sadoshima, J.6
-
28
-
-
77952489013
-
Nicotinamide adenine dinucleotide phosphate reduced oxidase 5 (Nox5) regulation by angiotensin II and endothelin-1 is mediated via calcium/calmodulin-dependent, rac-1-independent pathways in human endothelial cells
-
Montezano A.C., Burger D., Paravicini T.M., Chignalia A.Z., Yusuf H., Almasri M., et al. Nicotinamide adenine dinucleotide phosphate reduced oxidase 5 (Nox5) regulation by angiotensin II and endothelin-1 is mediated via calcium/calmodulin-dependent, rac-1-independent pathways in human endothelial cells. Circulation Research 2010, 106:1363-1373.
-
(2010)
Circulation Research
, vol.106
, pp. 1363-1373
-
-
Montezano, A.C.1
Burger, D.2
Paravicini, T.M.3
Chignalia, A.Z.4
Yusuf, H.5
Almasri, M.6
-
29
-
-
81155138290
-
Dual oxidase 2 is essential for the toll-like receptor 5-mediated inflammatory response in airway mucosa
-
Joo J.H., Ryu J.H., Kim C.H., Kim H.J., Suh M.S., Kim J.O., et al. Dual oxidase 2 is essential for the toll-like receptor 5-mediated inflammatory response in airway mucosa. Antioxidants and Redox Signalling 2011, 16:57-70.
-
(2011)
Antioxidants and Redox Signalling
, vol.16
, pp. 57-70
-
-
Joo, J.H.1
Ryu, J.H.2
Kim, C.H.3
Kim, H.J.4
Suh, M.S.5
Kim, J.O.6
-
30
-
-
0029775793
-
Regulation of xanthine dehydrogenase and xanthine oxidase activity by hypoxia
-
Poss W.B., Huecksteadt T.P., Panus P.C., Freeman B.A., Hoidal J.R. Regulation of xanthine dehydrogenase and xanthine oxidase activity by hypoxia. The American Journal of Physiology 1996, 270:L941-L946.
-
(1996)
The American Journal of Physiology
, vol.270
-
-
Poss, W.B.1
Huecksteadt, T.P.2
Panus, P.C.3
Freeman, B.A.4
Hoidal, J.R.5
-
31
-
-
57349166762
-
Differential effects of retinol and retinoic acid on cell proliferation: a role for reactive species and redox-dependent mechanisms in retinol supplementation
-
Zanotto-Filho A., Schroder R., Moreira J.C. Differential effects of retinol and retinoic acid on cell proliferation: a role for reactive species and redox-dependent mechanisms in retinol supplementation. Free Radical Research 2008, 42:778-788.
-
(2008)
Free Radical Research
, vol.42
, pp. 778-788
-
-
Zanotto-Filho, A.1
Schroder, R.2
Moreira, J.C.3
-
32
-
-
57649136749
-
Role of xanthine oxidase activation and reduced glutathione depletion in rhinovirus induction of inflammation in respiratory epithelial cells
-
Papi A., Contoli M., Gasparini P., Bristot L., Edwards M.R., Chicca M., et al. Role of xanthine oxidase activation and reduced glutathione depletion in rhinovirus induction of inflammation in respiratory epithelial cells. The Journal of Biological Chemistry 2008, 283:28595-28606.
-
(2008)
The Journal of Biological Chemistry
, vol.283
, pp. 28595-28606
-
-
Papi, A.1
Contoli, M.2
Gasparini, P.3
Bristot, L.4
Edwards, M.R.5
Chicca, M.6
-
33
-
-
82155188735
-
Xanthine oxidase-derived ROS upregulate Egr-1 via ERK1/2 in PA smooth muscle cells; model to test impact of extracellular ROS in chronic hypoxia
-
Hartney T., Birari R., Venkataraman S., Villegas L., Martinez M., Black S.M., et al. Xanthine oxidase-derived ROS upregulate Egr-1 via ERK1/2 in PA smooth muscle cells; model to test impact of extracellular ROS in chronic hypoxia. PLoS ONE 2011, 6:e27531.
-
(2011)
PLoS ONE
, vol.6
-
-
Hartney, T.1
Birari, R.2
Venkataraman, S.3
Villegas, L.4
Martinez, M.5
Black, S.M.6
-
34
-
-
32944467076
-
Mammalian polyamine catabolism: a therapeutic target, a pathological problem, or both?
-
Wang Y., Casero R.A. Mammalian polyamine catabolism: a therapeutic target, a pathological problem, or both?. Journal of Biochemistry 2006, 139:17-25.
-
(2006)
Journal of Biochemistry
, vol.139
, pp. 17-25
-
-
Wang, Y.1
Casero, R.A.2
-
35
-
-
33845730779
-
Tumor necrosis factor-alpha increases reactive oxygen species by inducing spermine oxidase in human lung epithelial cells: a potential mechanism for inflammation-induced carcinogenesis
-
Babbar N., Casero R.A. Tumor necrosis factor-alpha increases reactive oxygen species by inducing spermine oxidase in human lung epithelial cells: a potential mechanism for inflammation-induced carcinogenesis. Cancer Research 2006, 66:11125-11130.
-
(2006)
Cancer Research
, vol.66
, pp. 11125-11130
-
-
Babbar, N.1
Casero, R.A.2
-
36
-
-
4444268690
-
Mechanisms that regulate production of reactive oxygen species by cytochrome P450
-
Zangar R.C., Davydov D.R., Verma S. Mechanisms that regulate production of reactive oxygen species by cytochrome P450. Toxicology and Applied Pharmacology 2004, 199:316-331.
-
(2004)
Toxicology and Applied Pharmacology
, vol.199
, pp. 316-331
-
-
Zangar, R.C.1
Davydov, D.R.2
Verma, S.3
-
37
-
-
62249115660
-
Mitochondrial pathways for ROS formation and myocardial injury: the relevance of p66(Shc) and monoamine oxidase
-
Di Lisa F., Kaludercic N., Carpi A., Menabo R., Giorgio M. Mitochondrial pathways for ROS formation and myocardial injury: the relevance of p66(Shc) and monoamine oxidase. Basic Research in Cardiology 2009, 104:131-139.
-
(2009)
Basic Research in Cardiology
, vol.104
, pp. 131-139
-
-
Di Lisa, F.1
Kaludercic, N.2
Carpi, A.3
Menabo, R.4
Giorgio, M.5
-
38
-
-
58249093939
-
How mitochondria produce reactive oxygen species
-
Murphy M.P. How mitochondria produce reactive oxygen species. The Biochemical Journal 2009, 417:1-13.
-
(2009)
The Biochemical Journal
, vol.417
, pp. 1-13
-
-
Murphy, M.P.1
-
39
-
-
84863301287
-
Mitochondrial redox signalling at a glance
-
Collins Y., Chouchani E.T., James A.M., Menger K.E., Cocheme H.M., Murphy M.P. Mitochondrial redox signalling at a glance. Journal of Cell Science 2012, 125:801-806.
-
(2012)
Journal of Cell Science
, vol.125
, pp. 801-806
-
-
Collins, Y.1
Chouchani, E.T.2
James, A.M.3
Menger, K.E.4
Cocheme, H.M.5
Murphy, M.P.6
-
41
-
-
80052000670
-
Glutathione peroxidase-1 in health and disease: from molecular mechanisms to therapeutic opportunities
-
Lubos E., Loscalzo J., Handy D.E. Glutathione peroxidase-1 in health and disease: from molecular mechanisms to therapeutic opportunities. Antioxidants and Redox Signalling 2011, 15:1957-1997.
-
(2011)
Antioxidants and Redox Signalling
, vol.15
, pp. 1957-1997
-
-
Lubos, E.1
Loscalzo, J.2
Handy, D.E.3
-
42
-
-
84862818143
-
Mitochondria-ros crosstalk in the control of cell death and aging
-
Marchi S., Giorgi C., Suski J.M., Agnoletto C., Bononi A., Bonora M., et al. Mitochondria-ros crosstalk in the control of cell death and aging. Journal of Signal Transduction 2012, 2012:329635.
-
(2012)
Journal of Signal Transduction
, vol.2012
, pp. 329635
-
-
Marchi, S.1
Giorgi, C.2
Suski, J.M.3
Agnoletto, C.4
Bononi, A.5
Bonora, M.6
-
43
-
-
77952541558
-
The sites and topology of mitochondrial superoxide production
-
Brand M.D. The sites and topology of mitochondrial superoxide production. Experimental Gerontology 2010, 45:466-472.
-
(2010)
Experimental Gerontology
, vol.45
, pp. 466-472
-
-
Brand, M.D.1
-
44
-
-
0037160091
-
Topology of superoxide production from different sites in the mitochondrial electron transport chain
-
St-Pierre J., Buckingham J.A., Roebuck S.J., Brand M.D. Topology of superoxide production from different sites in the mitochondrial electron transport chain. The Journal of Biological Chemistry 2002, 277:44784-44790.
-
(2002)
The Journal of Biological Chemistry
, vol.277
, pp. 44784-44790
-
-
St-Pierre, J.1
Buckingham, J.A.2
Roebuck, S.J.3
Brand, M.D.4
-
45
-
-
0035816639
-
Leptin induces mitochondrial superoxide production and monocyte chemoattractant protein-1 expression in aortic endothelial cells by increasing fatty acid oxidation via protein kinase A
-
Yamagishi S.I., Edelstein D., Du X.L., Kaneda Y., Guzman M., Brownlee M. Leptin induces mitochondrial superoxide production and monocyte chemoattractant protein-1 expression in aortic endothelial cells by increasing fatty acid oxidation via protein kinase A. The Journal of Biological Chemistry 2001, 276:25096-25100.
-
(2001)
The Journal of Biological Chemistry
, vol.276
, pp. 25096-25100
-
-
Yamagishi, S.I.1
Edelstein, D.2
Du, X.L.3
Kaneda, Y.4
Guzman, M.5
Brownlee, M.6
-
46
-
-
18244379331
-
Superoxide activates mitochondrial uncoupling proteins
-
Echtay K.S., Roussel D., St-Pierre J., Jekabsons M.B., Cadenas S., Stuart J.A., et al. Superoxide activates mitochondrial uncoupling proteins. Nature 2002, 415:96-99.
-
(2002)
Nature
, vol.415
, pp. 96-99
-
-
Echtay, K.S.1
Roussel, D.2
St-Pierre, J.3
Jekabsons, M.B.4
Cadenas, S.5
Stuart, J.A.6
-
48
-
-
79952712223
-
Mitochondrial reactive oxygen species drive proinflammatory cytokine production
-
Naik E., Dixit V.M. Mitochondrial reactive oxygen species drive proinflammatory cytokine production. The Journal of Experimental Medicine 2011, 208:417-420.
-
(2011)
The Journal of Experimental Medicine
, vol.208
, pp. 417-420
-
-
Naik, E.1
Dixit, V.M.2
-
49
-
-
79551716551
-
Mitochondrial membrane potential is required for MAVS-mediated antiviral signaling
-
Koshiba T., Yasukawa K., Yanagi Y., Kawabata S. Mitochondrial membrane potential is required for MAVS-mediated antiviral signaling. Science Signaling 2011, 4:ra7.
-
(2011)
Science Signaling
, vol.4
-
-
Koshiba, T.1
Yasukawa, K.2
Yanagi, Y.3
Kawabata, S.4
-
50
-
-
70350365362
-
An N-terminal addressing sequence targets NLRX1 to the mitochondrial matrix
-
Arnoult D., Soares F., Tattoli I., Castanier C., Philpott D.J., Girardin S.E. An N-terminal addressing sequence targets NLRX1 to the mitochondrial matrix. Journal of Cell Science 2009, 122:3161-3168.
-
(2009)
Journal of Cell Science
, vol.122
, pp. 3161-3168
-
-
Arnoult, D.1
Soares, F.2
Tattoli, I.3
Castanier, C.4
Philpott, D.J.5
Girardin, S.E.6
-
51
-
-
38749097018
-
NLRX1 is a regulator of mitochondrial antiviral immunity
-
Moore C.B., Bergstralh D.T., Duncan J.A., Lei Y., Morrison T.E., Zimmermann A.G., et al. NLRX1 is a regulator of mitochondrial antiviral immunity. Nature 2008, 451:573-577.
-
(2008)
Nature
, vol.451
, pp. 573-577
-
-
Moore, C.B.1
Bergstralh, D.T.2
Duncan, J.A.3
Lei, Y.4
Morrison, T.E.5
Zimmermann, A.G.6
-
52
-
-
40249111682
-
NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-kappaB and JNK pathways by inducing reactive oxygen species production
-
Tattoli I., Carneiro L.A., Jehanno M., Magalhaes J.G., Shu Y., Philpott D.J., et al. NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-kappaB and JNK pathways by inducing reactive oxygen species production. EMBO Reports 2008, 9:293-300.
-
(2008)
EMBO Reports
, vol.9
, pp. 293-300
-
-
Tattoli, I.1
Carneiro, L.A.2
Jehanno, M.3
Magalhaes, J.G.4
Shu, Y.5
Philpott, D.J.6
-
53
-
-
79960205819
-
NLRX1/NOD5 deficiency does not affect MAVS signalling
-
Rebsamen M., Vazquez J., Tardivel A., Guarda G., Curran J., Tschopp J. NLRX1/NOD5 deficiency does not affect MAVS signalling. Cell Death and Differentiation 2011, 18:1387.
-
(2011)
Cell Death and Differentiation
, vol.18
, pp. 1387
-
-
Rebsamen, M.1
Vazquez, J.2
Tardivel, A.3
Guarda, G.4
Curran, J.5
Tschopp, J.6
-
54
-
-
77952409809
-
Mitochondrial dysfunction and oxidative stress mediate the physiological impairment induced by the disruption of autophagy
-
Wu J.J., Quijano C., Chen E., Liu H., Cao L., Fergusson M.M., et al. Mitochondrial dysfunction and oxidative stress mediate the physiological impairment induced by the disruption of autophagy. Aging 2009, 1:425-437.
-
(2009)
Aging
, vol.1
, pp. 425-437
-
-
Wu, J.J.1
Quijano, C.2
Chen, E.3
Liu, H.4
Cao, L.5
Fergusson, M.M.6
-
55
-
-
62449110463
-
Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling
-
Tal M.C., Sasai M., Lee H.K., Yordy B., Shadel G.S., Iwasaki A. Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling. Proceedings of the National Academy of Sciences of the United States of America 2009, 106:2770-2775.
-
(2009)
Proceedings of the National Academy of Sciences of the United States of America
, vol.106
, pp. 2770-2775
-
-
Tal, M.C.1
Sasai, M.2
Lee, H.K.3
Yordy, B.4
Shadel, G.S.5
Iwasaki, A.6
-
56
-
-
35348921764
-
The Atg5 Atg12 conjugate associates with innate antiviral immune responses
-
Jounai N., Takeshita F., Kobiyama K., Sawano A., Miyawaki A., Xin K.Q., et al. The Atg5 Atg12 conjugate associates with innate antiviral immune responses. Proceedings of the National Academy of Sciences of the United States of America 2007, 104:14050-14055.
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, pp. 14050-14055
-
-
Jounai, N.1
Takeshita, F.2
Kobiyama, K.3
Sawano, A.4
Miyawaki, A.5
Xin, K.Q.6
-
57
-
-
33750518197
-
The uncoupling protein 2 modulates the cytokine balance in innate immunity
-
Rousset S., Emre Y., Join-Lambert O., Hurtaud C., Ricquier D., Cassard-Doulcier A.M. The uncoupling protein 2 modulates the cytokine balance in innate immunity. Cytokine 2006, 35:135-142.
-
(2006)
Cytokine
, vol.35
, pp. 135-142
-
-
Rousset, S.1
Emre, Y.2
Join-Lambert, O.3
Hurtaud, C.4
Ricquier, D.5
Cassard-Doulcier, A.M.6
-
58
-
-
33847698059
-
Mitochondria contribute to LPS-induced MAPK activation via uncoupling protein UCP2 in macrophages
-
Emre Y., Hurtaud C., Nubel T., Criscuolo F., Ricquier D., Cassard-Doulcier A.M. Mitochondria contribute to LPS-induced MAPK activation via uncoupling protein UCP2 in macrophages. The Biochemical Journal 2007, 402:271-278.
-
(2007)
The Biochemical Journal
, vol.402
, pp. 271-278
-
-
Emre, Y.1
Hurtaud, C.2
Nubel, T.3
Criscuolo, F.4
Ricquier, D.5
Cassard-Doulcier, A.M.6
-
59
-
-
18144377756
-
Characterization of the differential expression of uncoupling protein 2 and ROS production in differentiated mouse macrophage-cells (Mm1) and the progenitor cells (M1)
-
Nishio K., Qiao S., Yamashita H. Characterization of the differential expression of uncoupling protein 2 and ROS production in differentiated mouse macrophage-cells (Mm1) and the progenitor cells (M1). Journal of Molecular Histology 2005, 36:35-44.
-
(2005)
Journal of Molecular Histology
, vol.36
, pp. 35-44
-
-
Nishio, K.1
Qiao, S.2
Yamashita, H.3
-
60
-
-
0033567388
-
ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway
-
Kopp E., Medzhitov R., Carothers J., Xiao C., Douglas I., Janeway C.A., et al. ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway. Genes & Development 1999, 13:2059-2071.
-
(1999)
Genes & Development
, vol.13
, pp. 2059-2071
-
-
Kopp, E.1
Medzhitov, R.2
Carothers, J.3
Xiao, C.4
Douglas, I.5
Janeway, C.A.6
-
61
-
-
33947129099
-
Cytosolic signaling protein Ecsit also localizes to mitochondria where it interacts with chaperone NDUFAF1 and functions in complex I assembly
-
Vogel R.O., Janssen R.J., van den Brand M.A., Dieteren C.E., Verkaart S., Koopman W.J., et al. Cytosolic signaling protein Ecsit also localizes to mitochondria where it interacts with chaperone NDUFAF1 and functions in complex I assembly. Genes & Development 2007, 21:615-624.
-
(2007)
Genes & Development
, vol.21
, pp. 615-624
-
-
Vogel, R.O.1
Janssen, R.J.2
van den Brand, M.A.3
Dieteren, C.E.4
Verkaart, S.5
Koopman, W.J.6
-
62
-
-
79955532516
-
TLR signalling augments macrophage bactericidal activity through mitochondrial ROS
-
West A.P., Brodsky I.E., Rahner C., Woo D.K., Erdjument-Bromage H., Tempst P., et al. TLR signalling augments macrophage bactericidal activity through mitochondrial ROS. Nature 2011, 472:476-480.
-
(2011)
Nature
, vol.472
, pp. 476-480
-
-
West, A.P.1
Brodsky, I.E.2
Rahner, C.3
Woo, D.K.4
Erdjument-Bromage, H.5
Tempst, P.6
-
63
-
-
75649096002
-
Thioredoxin-interacting protein links oxidative stress to inflammasome activation
-
Zhou R., Tardivel A., Thorens B., Choi I., Tschopp J. Thioredoxin-interacting protein links oxidative stress to inflammasome activation. Nature Immunology 2010, 11:136-140.
-
(2010)
Nature Immunology
, vol.11
, pp. 136-140
-
-
Zhou, R.1
Tardivel, A.2
Thorens, B.3
Choi, I.4
Tschopp, J.5
-
64
-
-
79951642032
-
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
-
Nakahira K., Haspel J.A., Rathinam V.A., Lee S.J., Dolinay T., Lam H.C., et al. Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nature Immunology 2011, 12:222-230.
-
(2011)
Nature Immunology
, vol.12
, pp. 222-230
-
-
Nakahira, K.1
Haspel, J.A.2
Rathinam, V.A.3
Lee, S.J.4
Dolinay, T.5
Lam, H.C.6
-
65
-
-
78651393239
-
A role for mitochondria in NLRP3 inflammasome activation
-
Zhou R., Yazdi A.S., Menu P., Tschopp J. A role for mitochondria in NLRP3 inflammasome activation. Nature 2011, 469:221-225.
-
(2011)
Nature
, vol.469
, pp. 221-225
-
-
Zhou, R.1
Yazdi, A.S.2
Menu, P.3
Tschopp, J.4
-
66
-
-
84860883878
-
DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88
-
Tarallo V., Hirano Y., Gelfand B.D., Dridi S., Kerur N., Kim Y., et al. DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88. Cell 2012, 149:847-859.
-
(2012)
Cell
, vol.149
, pp. 847-859
-
-
Tarallo, V.1
Hirano, Y.2
Gelfand, B.D.3
Dridi, S.4
Kerur, N.5
Kim, Y.6
-
67
-
-
79960920271
-
NLRP3 inflammasomes link inflammation and metabolic disease
-
De Nardo D., Latz E. NLRP3 inflammasomes link inflammation and metabolic disease. Trends in Immunology 2011, 32:373-379.
-
(2011)
Trends in Immunology
, vol.32
, pp. 373-379
-
-
De Nardo, D.1
Latz, E.2
-
68
-
-
14844327760
-
Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases
-
Kamata H., Honda S., Maeda S., Chang L., Hirata H., Karin M. Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases. Cell 2005, 120:649-661.
-
(2005)
Cell
, vol.120
, pp. 649-661
-
-
Kamata, H.1
Honda, S.2
Maeda, S.3
Chang, L.4
Hirata, H.5
Karin, M.6
-
69
-
-
0032578458
-
Mitochondrial reactive oxygen species trigger hypoxia-induced transcription
-
Chandel N.S., Maltepe E., Goldwasser E., Mathieu C.E., Simon M.C., Schumacker P.T. Mitochondrial reactive oxygen species trigger hypoxia-induced transcription. Proceedings of the National Academy of Sciences of the United States of America 1998, 95:11715-11720.
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, pp. 11715-11720
-
-
Chandel, N.S.1
Maltepe, E.2
Goldwasser, E.3
Mathieu, C.E.4
Simon, M.C.5
Schumacker, P.T.6
-
72
-
-
77955494531
-
Thioredoxin-interacting protein (TXNIP) gene expression: sensing oxidative phosphorylation status and glycolytic rate
-
Yu F.X., Chai T.F., He H., Hagen T., Luo Y. Thioredoxin-interacting protein (TXNIP) gene expression: sensing oxidative phosphorylation status and glycolytic rate. Journal of Biological Chemistry 2010, 285:25822-25830.
-
(2010)
Journal of Biological Chemistry
, vol.285
, pp. 25822-25830
-
-
Yu, F.X.1
Chai, T.F.2
He, H.3
Hagen, T.4
Luo, Y.5
-
73
-
-
43249104789
-
Ceramide induces p38 MAPK and JNK activation through a mechanism involving a thioredoxin-interacting protein-mediated pathway
-
Chen C.L., Lin C.F., Chang W.T., Huang W.C., Teng C.F., Lin Y.S. Ceramide induces p38 MAPK and JNK activation through a mechanism involving a thioredoxin-interacting protein-mediated pathway. Blood 2008, 111:4365-4374.
-
(2008)
Blood
, vol.111
, pp. 4365-4374
-
-
Chen, C.L.1
Lin, C.F.2
Chang, W.T.3
Huang, W.C.4
Teng, C.F.5
Lin, Y.S.6
-
74
-
-
79960542894
-
Cutting edge: reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome
-
Bauernfeind F., Bartok E., Rieger A., Franchi L., Nunez G., Hornung V. Cutting edge: reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome. Journal of Immunology 2011, 187:613-617.
-
(2011)
Journal of Immunology
, vol.187
, pp. 613-617
-
-
Bauernfeind, F.1
Bartok, E.2
Rieger, A.3
Franchi, L.4
Nunez, G.5
Hornung, V.6
-
75
-
-
0033515520
-
Germline mutations in the extracellular domains of the 55kDa TNF receptor, TNFR1, define a family of dominantly inherited autoinflammatory syndromes
-
McDermott M.F., Aksentijevich I., Galon J., McDermott E.M., Ogunkolade B.W., Centola M., et al. Germline mutations in the extracellular domains of the 55kDa TNF receptor, TNFR1, define a family of dominantly inherited autoinflammatory syndromes. Cell 1999, 97:133-144.
-
(1999)
Cell
, vol.97
, pp. 133-144
-
-
McDermott, M.F.1
Aksentijevich, I.2
Galon, J.3
McDermott, E.M.4
Ogunkolade, B.W.5
Centola, M.6
-
76
-
-
60349084974
-
Hydrogen peroxide-induced neuronal apoptosis is associated with inhibition of protein phosphatase 2A and 5, leading to activation of MAPK pathway
-
Chen L., Liu L., Yin J., Luo Y., Huang S. Hydrogen peroxide-induced neuronal apoptosis is associated with inhibition of protein phosphatase 2A and 5, leading to activation of MAPK pathway. International Journal of Biochemistry and Cell Biology 2009, 41:1284-1295.
-
(2009)
International Journal of Biochemistry and Cell Biology
, vol.41
, pp. 1284-1295
-
-
Chen, L.1
Liu, L.2
Yin, J.3
Luo, Y.4
Huang, S.5
-
77
-
-
79952184583
-
Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)
-
Bulua A.C., Simon A., Maddipati R., Pelletier M., Park H., Kim K.Y., et al. Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS). The Journal of Experimental Medicine 2011, 208:519-533.
-
(2011)
The Journal of Experimental Medicine
, vol.208
, pp. 519-533
-
-
Bulua, A.C.1
Simon, A.2
Maddipati, R.3
Pelletier, M.4
Park, H.5
Kim, K.Y.6
-
78
-
-
1042299013
-
Targeting coenzyme Q derivatives to mitochondria
-
Smith R.A., Kelso G.F., James A.M., Murphy M.P. Targeting coenzyme Q derivatives to mitochondria. Methods in Enzymology 2004, 382:45-67.
-
(2004)
Methods in Enzymology
, vol.382
, pp. 45-67
-
-
Smith, R.A.1
Kelso, G.F.2
James, A.M.3
Murphy, M.P.4
-
81
-
-
0019969614
-
Energy metabolism of human neutrophils during phagocytosis
-
Borregaard N., Herlin T. Energy metabolism of human neutrophils during phagocytosis. Journal of Clinical Investigation 1982, 70:550-557.
-
(1982)
Journal of Clinical Investigation
, vol.70
, pp. 550-557
-
-
Borregaard, N.1
Herlin, T.2
-
82
-
-
0033405817
-
Macrophage responses to hypoxia: relevance to disease mechanisms
-
Lewis J.S., Lee J.A., Underwood J.C., Harris A.L., Lewis C.E. Macrophage responses to hypoxia: relevance to disease mechanisms. Journal of Leukocyte Biology 1999, 66:889-900.
-
(1999)
Journal of Leukocyte Biology
, vol.66
, pp. 889-900
-
-
Lewis, J.S.1
Lee, J.A.2
Underwood, J.C.3
Harris, A.L.4
Lewis, C.E.5
-
83
-
-
0014273870
-
Electron microscopic studies of human granulocytes: structural variations related to function
-
Zucker-Franklin D. Electron microscopic studies of human granulocytes: structural variations related to function. Seminars in Hematology 1968, 5:109-133.
-
(1968)
Seminars in Hematology
, vol.5
, pp. 109-133
-
-
Zucker-Franklin, D.1
-
84
-
-
0742306781
-
Functional characterization of mitochondria in neutrophils: a role restricted to apoptosis
-
Maianski N.A., Geissler J., Srinivasula S.M., Alnemri E.S., Roos D., Kuijpers T.W. Functional characterization of mitochondria in neutrophils: a role restricted to apoptosis. Cell Death and Differentiation 2004, 11:143-153.
-
(2004)
Cell Death and Differentiation
, vol.11
, pp. 143-153
-
-
Maianski, N.A.1
Geissler, J.2
Srinivasula, S.M.3
Alnemri, E.S.4
Roos, D.5
Kuijpers, T.W.6
-
85
-
-
44349150953
-
Mitochondrial membrane potential in human neutrophils is maintained by complex III activity in the absence of supercomplex organisation
-
van Raam B.J., Sluiter W., de Wit E., Roos D., Verhoeven A.J., Kuijpers T.W. Mitochondrial membrane potential in human neutrophils is maintained by complex III activity in the absence of supercomplex organisation. PLoS ONE 2008, 3:e2013.
-
(2008)
PLoS ONE
, vol.3
-
-
van Raam, B.J.1
Sluiter, W.2
de Wit, E.3
Roos, D.4
Verhoeven, A.J.5
Kuijpers, T.W.6
-
86
-
-
0037423948
-
HIF-1alpha is essential for myeloid cell-mediated inflammation
-
Cramer T., Yamanishi Y., Clausen B.E., Forster I., Pawlinski R., Mackman N., et al. HIF-1alpha is essential for myeloid cell-mediated inflammation. Cell 2003, 112:645-657.
-
(2003)
Cell
, vol.112
, pp. 645-657
-
-
Cramer, T.1
Yamanishi, Y.2
Clausen, B.E.3
Forster, I.4
Pawlinski, R.5
Mackman, N.6
-
87
-
-
79960683641
-
Activation of hypoxia-inducible factor-1alpha (Hif-1alpha) delays inflammation resolution by reducing neutrophil apoptosis and reverse migration in a zebrafish inflammation model
-
Elks P.M., van Eeden F.J., Dixon G., Wang X., Reyes-Aldasoro C.C., Ingham P.W., et al. Activation of hypoxia-inducible factor-1alpha (Hif-1alpha) delays inflammation resolution by reducing neutrophil apoptosis and reverse migration in a zebrafish inflammation model. Blood 2011, 118:712-722.
-
(2011)
Blood
, vol.118
, pp. 712-722
-
-
Elks, P.M.1
van Eeden, F.J.2
Dixon, G.3
Wang, X.4
Reyes-Aldasoro, C.C.5
Ingham, P.W.6
-
88
-
-
0033587146
-
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
-
Maxwell P.H., Wiesener M.S., Chang G.W., Clifford S.C., Vaux E.C., Cockman M.E., et al. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature 1999, 399:271-275.
-
(1999)
Nature
, vol.399
, pp. 271-275
-
-
Maxwell, P.H.1
Wiesener, M.S.2
Chang, G.W.3
Clifford, S.C.4
Vaux, E.C.5
Cockman, M.E.6
-
89
-
-
35148828429
-
Hypoxia-inducible factor 1 (HIF-1) pathway
-
Semenza G.L. Hypoxia-inducible factor 1 (HIF-1) pathway. Science's STKE 2007, 2007:cm8.
-
(2007)
Science's STKE
, vol.2007
-
-
Semenza, G.L.1
-
90
-
-
33846630894
-
Multiple factors affecting cellular redox status and energy metabolism modulate hypoxia-inducible factor prolyl hydroxylase activity in vivo and in vitro
-
Pan Y., Mansfield K.D., Bertozzi C.C., Rudenko V., Chan D.A., Giaccia A.J., et al. Multiple factors affecting cellular redox status and energy metabolism modulate hypoxia-inducible factor prolyl hydroxylase activity in vivo and in vitro. Molecular and Cellular Biology 2007, 27:912-925.
-
(2007)
Molecular and Cellular Biology
, vol.27
, pp. 912-925
-
-
Pan, Y.1
Mansfield, K.D.2
Bertozzi, C.C.3
Rudenko, V.4
Chan, D.A.5
Giaccia, A.J.6
-
91
-
-
22144492953
-
HIF-1alpha expression regulates the bactericidal capacity of phagocytes
-
Peyssonnaux C., Datta V., Cramer T., Doedens A., Theodorakis E.A., Gallo R.L., et al. HIF-1alpha expression regulates the bactericidal capacity of phagocytes. Journal of Clinical Investigation 2005, 115:1806-1815.
-
(2005)
Journal of Clinical Investigation
, vol.115
, pp. 1806-1815
-
-
Peyssonnaux, C.1
Datta, V.2
Cramer, T.3
Doedens, A.4
Theodorakis, E.A.5
Gallo, R.L.6
-
92
-
-
44849100198
-
NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha
-
Rius J., Guma M., Schachtrup C., Akassoglou K., Zinkernagel A.S., Nizet V., et al. NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha. Nature 2008, 453:807-811.
-
(2008)
Nature
, vol.453
, pp. 807-811
-
-
Rius, J.1
Guma, M.2
Schachtrup, C.3
Akassoglou, K.4
Zinkernagel, A.S.5
Nizet, V.6
-
93
-
-
1642581653
-
Hypoxic gene activation by lipopolysaccharide in macrophages: implication of hypoxia-inducible factor 1alpha
-
Blouin C.C., Page E.L., Soucy G.M., Richard D.E. Hypoxic gene activation by lipopolysaccharide in macrophages: implication of hypoxia-inducible factor 1alpha. Blood 2004, 103:1124-1130.
-
(2004)
Blood
, vol.103
, pp. 1124-1130
-
-
Blouin, C.C.1
Page, E.L.2
Soucy, G.M.3
Richard, D.E.4
-
94
-
-
0034936994
-
Expression of hypoxia-inducible factor 1alpha by macrophages in the rheumatoid synovium: implications for targeting of therapeutic genes to the inflamed joint
-
Hollander A.P., Corke K.P., Freemont A.J., Lewis C.E. Expression of hypoxia-inducible factor 1alpha by macrophages in the rheumatoid synovium: implications for targeting of therapeutic genes to the inflamed joint. Arthritis and Rheumatism 2001, 44:1540-1544.
-
(2001)
Arthritis and Rheumatism
, vol.44
, pp. 1540-1544
-
-
Hollander, A.P.1
Corke, K.P.2
Freemont, A.J.3
Lewis, C.E.4
-
95
-
-
77954735369
-
Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation
-
Krawczyk C.M., Holowka T., Sun J., Blagih J., Amiel E., DeBerardinis R.J., et al. Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation. Blood 2010, 115:4742-4749.
-
(2010)
Blood
, vol.115
, pp. 4742-4749
-
-
Krawczyk, C.M.1
Holowka, T.2
Sun, J.3
Blagih, J.4
Amiel, E.5
DeBerardinis, R.J.6
-
96
-
-
84865197492
-
Commitment to glycolysis sustains survival of NO-producing inflammatory dendritic cells
-
Everts B., Amiel E., van der Windt G.J., Freitas T.C., Chott R., Yarasheski K.E., et al. Commitment to glycolysis sustains survival of NO-producing inflammatory dendritic cells. Blood 2012, 120:1422-1431.
-
(2012)
Blood
, vol.120
, pp. 1422-1431
-
-
Everts, B.1
Amiel, E.2
van der Windt, G.J.3
Freitas, T.C.4
Chott, R.5
Yarasheski, K.E.6
-
97
-
-
54249141095
-
Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival
-
Maciver N.J., Jacobs S.R., Wieman H.L., Wofford J.A., Coloff J.L., Rathmell J.C. Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival. Journal of Leukocyte Biology 2008, 84:949-957.
-
(2008)
Journal of Leukocyte Biology
, vol.84
, pp. 949-957
-
-
Maciver, N.J.1
Jacobs, S.R.2
Wieman, H.L.3
Wofford, J.A.4
Coloff, J.L.5
Rathmell, J.C.6
-
98
-
-
34548014737
-
Revving the engine: signal transduction fuels T cell activation
-
Jones R.G., Thompson C.B. Revving the engine: signal transduction fuels T cell activation. Immunity 2007, 27:173-178.
-
(2007)
Immunity
, vol.27
, pp. 173-178
-
-
Jones, R.G.1
Thompson, C.B.2
-
100
-
-
44449165597
-
Glucose uptake is limiting in T cell activation and requires CD28-mediated Akt-dependent and independent pathways
-
Jacobs S.R., Herman C.E., Maciver N.J., Wofford J.A., Wieman H.L., Hammen J.J., et al. Glucose uptake is limiting in T cell activation and requires CD28-mediated Akt-dependent and independent pathways. Journal of Immunology 2008, 180:4476-4486.
-
(2008)
Journal of Immunology
, vol.180
, pp. 4476-4486
-
-
Jacobs, S.R.1
Herman, C.E.2
Maciver, N.J.3
Wofford, J.A.4
Wieman, H.L.5
Hammen, J.J.6
-
101
-
-
33744462050
-
Antigen receptor-mediated changes in glucose metabolism in B lymphocytes: role of phosphatidylinositol 3-kinase signaling in the glycolytic control of growth
-
Doughty C.A., Bleiman B.F., Wagner D.J., Dufort F.J., Mataraza J.M., Roberts M.F., et al. Antigen receptor-mediated changes in glucose metabolism in B lymphocytes: role of phosphatidylinositol 3-kinase signaling in the glycolytic control of growth. Blood 2006, 107:4458-4465.
-
(2006)
Blood
, vol.107
, pp. 4458-4465
-
-
Doughty, C.A.1
Bleiman, B.F.2
Wagner, D.J.3
Dufort, F.J.4
Mataraza, J.M.5
Roberts, M.F.6
-
102
-
-
0034904776
-
Growth factors can influence cell growth and survival through effects on glucose metabolism
-
Vander Heiden M.G., Plas D.R., Rathmell J.C., Fox C.J., Harris M.H., Thompson C.B. Growth factors can influence cell growth and survival through effects on glucose metabolism. Molecular and Cellular Biology 2001, 21:5899-5912.
-
(2001)
Molecular and Cellular Biology
, vol.21
, pp. 5899-5912
-
-
Vander Heiden, M.G.1
Plas, D.R.2
Rathmell, J.C.3
Fox, C.J.4
Harris, M.H.5
Thompson, C.B.6
-
103
-
-
0242285719
-
STAT proteins: from normal control of cellular events to tumorigenesis
-
Calo V., Migliavacca M., Bazan V., Macaluso M., Buscemi M., Gebbia N., et al. STAT proteins: from normal control of cellular events to tumorigenesis. Journal of Cellular Physiology 2003, 197:157-168.
-
(2003)
Journal of Cellular Physiology
, vol.197
, pp. 157-168
-
-
Calo, V.1
Migliavacca, M.2
Bazan, V.3
Macaluso, M.4
Buscemi, M.5
Gebbia, N.6
-
104
-
-
39549091298
-
Signal transduction pathways and transcriptional regulation in the control of Th17 differentiation
-
Chen Z., Laurence A., O'Shea J.J. Signal transduction pathways and transcriptional regulation in the control of Th17 differentiation. Seminars in Immunology 2007, 19:400-408.
-
(2007)
Seminars in Immunology
, vol.19
, pp. 400-408
-
-
Chen, Z.1
Laurence, A.2
O'Shea, J.J.3
-
105
-
-
77949727731
-
Disruption of astrocyte STAT3 signaling decreases mitochondrial function and increases oxidative stress in vitro
-
Sarafian T.A., Montes C., Imura T., Qi J., Coppola G., Geschwind D.H., et al. Disruption of astrocyte STAT3 signaling decreases mitochondrial function and increases oxidative stress in vitro. PLoS ONE 2010, 5:e9532.
-
(2010)
PLoS ONE
, vol.5
-
-
Sarafian, T.A.1
Montes, C.2
Imura, T.3
Qi, J.4
Coppola, G.5
Geschwind, D.H.6
-
106
-
-
59849101586
-
Function of mitochondrial Stat3 in cellular respiration
-
Wegrzyn J., Potla R., Chwae Y.J., Sepuri N.B., Zhang Q., Koeck T., et al. Function of mitochondrial Stat3 in cellular respiration. Science 2009, 323:793-797.
-
(2009)
Science
, vol.323
, pp. 793-797
-
-
Wegrzyn, J.1
Potla, R.2
Chwae, Y.J.3
Sepuri, N.B.4
Zhang, Q.5
Koeck, T.6
-
107
-
-
84864324029
-
GRIM-19-mediated translocation of STAT3 to mitochondria is necessary for TNF-induced necroptosis
-
Shulga N., Pastorino J.G. GRIM-19-mediated translocation of STAT3 to mitochondria is necessary for TNF-induced necroptosis. Journal of Cell Science 2012, 125:2995-3003.
-
(2012)
Journal of Cell Science
, vol.125
, pp. 2995-3003
-
-
Shulga, N.1
Pastorino, J.G.2
-
109
-
-
84863228835
-
Sustained response and prevention of damage progression in patients with neonatal-onset multisystem inflammatory disease treated with anakinra: a cohort study to determine three- and five-year outcomes
-
Sibley C.H., Plass N., Snow J., Wiggs E.A., Brewer C.C., King K.A., et al. Sustained response and prevention of damage progression in patients with neonatal-onset multisystem inflammatory disease treated with anakinra: a cohort study to determine three- and five-year outcomes. Arthritis and Rheumatism 2012, 64:2375-2386.
-
(2012)
Arthritis and Rheumatism
, vol.64
, pp. 2375-2386
-
-
Sibley, C.H.1
Plass, N.2
Snow, J.3
Wiggs, E.A.4
Brewer, C.C.5
King, K.A.6
-
110
-
-
77950363011
-
Autoinflammatory disease reloaded: a clinical perspective
-
Kastner D., Aksentijevich I., Goldbach-Mansky R. Autoinflammatory disease reloaded: a clinical perspective. Cell 2010, 140:784-790.
-
(2010)
Cell
, vol.140
, pp. 784-790
-
-
Kastner, D.1
Aksentijevich, I.2
Goldbach-Mansky, R.3
-
111
-
-
84857739991
-
Efficacy of etanercept in the tumor necrosis factor receptor-associated periodic syndrome (TRAPS)
-
Bulua A.C., Mogul D.B., Aksentijevich I., Singh H., He D., Muenz L., et al. Efficacy of etanercept in the tumor necrosis factor receptor-associated periodic syndrome (TRAPS). Arthritis and Rheumatism 2011, 64:908-913.
-
(2011)
Arthritis and Rheumatism
, vol.64
, pp. 908-913
-
-
Bulua, A.C.1
Mogul, D.B.2
Aksentijevich, I.3
Singh, H.4
He, D.5
Muenz, L.6
-
112
-
-
84861841056
-
Mitochondrial pharmacology
-
Smith R.A., Hartley R.C., Cocheme H.M., Murphy M.P. Mitochondrial pharmacology. Trends in Pharmacological Sciences 2012, 33:341-352.
-
(2012)
Trends in Pharmacological Sciences
, vol.33
, pp. 341-352
-
-
Smith, R.A.1
Hartley, R.C.2
Cocheme, H.M.3
Murphy, M.P.4
-
114
-
-
56049120778
-
The mitochondria-targeted antioxidant MitoQ protects against organ damage in a lipopolysaccharide-peptidoglycan model of sepsis
-
Lowes D.A., Thottakam B.M., Webster N.R., Murphy M.P., Galley H.F. The mitochondria-targeted antioxidant MitoQ protects against organ damage in a lipopolysaccharide-peptidoglycan model of sepsis. Free Radical Biology and Medicine 2008, 45:1559-1565.
-
(2008)
Free Radical Biology and Medicine
, vol.45
, pp. 1559-1565
-
-
Lowes, D.A.1
Thottakam, B.M.2
Webster, N.R.3
Murphy, M.P.4
Galley, H.F.5
-
115
-
-
78649755150
-
Prevention of diabetic nephropathy in Ins2(+/)(AkitaJ) mice by the mitochondria-targeted therapy MitoQ
-
Chacko B.K., Reily C., Srivastava A., Johnson M.S., Ye Y., Ulasova E., et al. Prevention of diabetic nephropathy in Ins2(+/)(AkitaJ) mice by the mitochondria-targeted therapy MitoQ. Biochemical Journal 2010, 432:9-19.
-
(2010)
Biochemical Journal
, vol.432
, pp. 9-19
-
-
Chacko, B.K.1
Reily, C.2
Srivastava, A.3
Johnson, M.S.4
Ye, Y.5
Ulasova, E.6
-
116
-
-
77955792985
-
A double-blind, placebo-controlled study to assess the mitochondria-targeted antioxidant MitoQ as a disease-modifying therapy in Parkinson's disease
-
Snow B.J., Rolfe F.L., Lockhart M.M., Frampton C.M., O'Sullivan J.D., Fung V., et al. A double-blind, placebo-controlled study to assess the mitochondria-targeted antioxidant MitoQ as a disease-modifying therapy in Parkinson's disease. Movement Disorders 2010, 25:1670-1674.
-
(2010)
Movement Disorders
, vol.25
, pp. 1670-1674
-
-
Snow, B.J.1
Rolfe, F.L.2
Lockhart, M.M.3
Frampton, C.M.4
O'Sullivan, J.D.5
Fung, V.6
-
117
-
-
77956496245
-
The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a Phase II study of hepatitis C patients
-
Gane E.J., Weilert F., Orr D.W., Keogh G.F., Gibson M., Lockhart M.M., et al. The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a Phase II study of hepatitis C patients. Liver International 2010, 30:1019-1026.
-
(2010)
Liver International
, vol.30
, pp. 1019-1026
-
-
Gane, E.J.1
Weilert, F.2
Orr, D.W.3
Keogh, G.F.4
Gibson, M.5
Lockhart, M.M.6
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