Deficiency of NADPH oxidase components p47phox and gp91phox caused granulomatous synovitis and increased connective tissue destruction in experimental arthritis models

American Journal of Pathology

Volumn 163, Issue 4, 2003, Pages 1525-1537

  Van de Loo, Fons A J ^a   Bennink, Miranda B ^a   Arntz, Onno J ^a   Smeets, Ruben L ^a   Lubberts, Erik ^a   Joosten, Leo A B ^a   Van Lent, Peter L E M ^a   Coenen de Roo, Christina J J ^b   Cuzzocrea, Salvatore ^c   Segal, Brahm H ^d   Holland, Steven M ^d   Van den Berg, Wim B ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b NV ORGANON   (Netherlands)

^c UNIVERSITY OF MESSINA   (Italy)

^d NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C3; GELATINASE B; GLYCOPROTEIN; INTERLEUKIN 1ALPHA; OXYGEN RADICAL; PROTEIN P47; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; STROMELYSIN; TARTARIC ACID; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRITIS; ARTICLE; BONE EROSION; CATALYSIS; CELL DEATH; COMPLEMENT ACTIVATION; CONNECTIVE TISSUE DISEASE; CONTROLLED STUDY; ENZYME DEFICIENCY; GENE EXPRESSION REGULATION; GRANULOMATOUS INFLAMMATION; IMMUNE COMPLEX DISEASE; MOUSE; NONHUMAN; OSTEOCLAST; OSTEOLYSIS; PRIORITY JOURNAL; SYNOVITIS; TISSUE DEGENERATION;

EID: 0141648399     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)63509-2     Document Type: Article

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