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Volumn 9, Issue , 2012, Pages

LPS induced inflammatory responses in human peripheral blood mononuclear cells is mediated through NOX4 and G iα dependent PI-3kinase signalling

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; APOCYNIN; GUANINE NUCLEOTIDE BINDING PROTEIN; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MASTOPARAN; PERTUSSIS TOXIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; TOLL LIKE RECEPTOR 4; WORTMANNIN;

EID: 84855604126     PISSN: None     EISSN: 14769255     Source Type: Journal    
DOI: 10.1186/1476-9255-9-1     Document Type: Article
Times cited : (165)

References (35)
  • 1
    • 0029890168 scopus 로고    scopus 로고
    • Endotoxin signal transduction in macrophages
    • Endotoxin signal transduction in macrophages. Sweet MJ, Hume DA, J Leukoc Biol 1996 60 1 8 26 8699127 (Pubitemid 26248877)
    • (1996) Journal of Leukocyte Biology , vol.60 , Issue.1 , pp. 8-26
    • Sweet, M.J.1    Hume, D.A.2
  • 2
    • 0141532262 scopus 로고    scopus 로고
    • Toll-like receptor signaling
    • DOI 10.1074/jbc.R300028200
    • Toll-like receptor signaling. Akira S, J Biol Chem 2003 278 40 38105 8 10.1074/jbc.R300028200 12893815 (Pubitemid 37221695)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.40 , pp. 38105-38108
    • Akira, S.1
  • 3
    • 0033557176 scopus 로고    scopus 로고
    • Toll, a new piece in the puzzle of innate immunity
    • DOI 10.1084/jem.189.4.605
    • Toll, a new piece in the puzzle of innate immunity. Wright SD, J Exp Med 1999 189 4 605 9 10.1084/jem.189.4.605 9989974 (Pubitemid 29193360)
    • (1999) Journal of Experimental Medicine , vol.189 , Issue.4 , pp. 605-609
    • Wright, S.D.1
  • 6
    • 0034886143 scopus 로고    scopus 로고
    • Toll-like receptors: Critical proteins linking innate and acquired immunity
    • DOI 10.1038/90609
    • Toll-like receptors: critical proteins linking innate and acquired immunity. Akira S, Takeda K, Kaisho T, Nat Immunol 2001 2 8 675 80 10.1038/90609 11477402 (Pubitemid 32747155)
    • (2001) Nature Immunology , vol.2 , Issue.8 , pp. 675-680
    • Akira, S.1    Takeda, K.2    Kaisho, T.3
  • 7
    • 4644350365 scopus 로고    scopus 로고
    • Cutting edge: Direct interaction of TLR4 with NAD(P)H oxidase 4 isozyme is essential for lipopolysaccharide-induced production of reactive oxygen species and activation of NF-κB
    • Cutting edge: direct interaction of TLR4 with NAD(P)H oxidase 4 isozyme is essential for lipopolysaccharide-induced production of reactive oxygen species and activation of NF-kappa. Park HS, et al. B J Immunol 2004 173 6 3589 93 (Pubitemid 39280716)
    • (2004) Journal of Immunology , vol.173 , Issue.6 , pp. 3589-3593
    • Park, H.S.1    Jung, H.Y.2    Park, E.Y.3    Kim, J.4    Lee, W.J.5    Bae, Y.S.6
  • 8
    • 0034079862 scopus 로고    scopus 로고
    • Free radicals and antioxidants in the year 2000. A historical look to the future
    • Free radicals and antioxidants in the year 2000. A historical look to the future. Gutteridge JM, Halliwell B, Ann N Y Acad Sci 2000 899 136 47 10863535 (Pubitemid 30352782)
    • (2000) Annals of the New York Academy of Sciences , vol.899 , pp. 136-147
    • Gutteridge, J.M.C.1    Halliwell, B.2
  • 9
    • 33750620057 scopus 로고    scopus 로고
    • Oxidative stress and redox regulation of lung inflammation in COPD
    • DOI 10.1183/09031936.06.00053805
    • Oxidative stress and redox regulation of lung inflammation in COPD. Rahman I, Adcock IM, Eur Respir J 2006 28 1 219 42 10.1183/09031936.06.00053805 16816350 (Pubitemid 44914279)
    • (2006) European Respiratory Journal , vol.28 , Issue.1 , pp. 219-242
    • Rahman, I.1    Adcock, I.M.2
  • 10
    • 0034190367 scopus 로고    scopus 로고
    • Recent advances towards understanding redox mechanisms in the activation of nuclear factor κB
    • DOI 10.1016/S0891-5849(00)00218-5, PII S0891584900002185
    • Recent advances towards understanding redox mechanisms in the activation of nuclear factor kappaB. Janssen-Heininger YM, Poynter ME, Baeuerle PA, Free Radic Biol Med 2000 28 9 1317 27 10.1016/S0891-5849(00)00218-5 10924851 (Pubitemid 30621476)
    • (2000) Free Radical Biology and Medicine , vol.28 , Issue.9 , pp. 1317-1327
    • Janssen-Heininger, Y.M.W.1    Poynter, M.E.2    Baeuerle, P.A.3
  • 11
    • 0842321777 scopus 로고    scopus 로고
    • Involvement of Reactive Oxygen Species in Toll-Like Receptor 4-Dependent Activation of NF-κB
    • Involvement of reactive oxygen species in Toll-like receptor 4-dependent activation of NF-kappa B. Asehnoune K, et al. J Immunol 2004 172 4 2522 9 14764725 (Pubitemid 38182403)
    • (2004) Journal of Immunology , vol.172 , Issue.4 , pp. 2522-2529
    • Asehnoune, K.1    Strassheim, D.2    Mitra, S.3    Kim, J.Y.4    Abraham, E.5
  • 12
    • 76349087609 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase isoforms as targets in respiratory disease
    • Phosphatidylinositol 3-kinase isoforms as targets in respiratory disease. Marwick JA, Chung KF, Adcock IM, Ther Adv Respir Dis 4 1 19 34
    • Ther Adv Respir Dis , vol.4 , Issue.1 , pp. 19-34
    • Marwick, J.A.1    Chung, K.F.2    Adcock, I.M.3
  • 14
    • 0037205048 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase pathway
    • DOI 10.1126/science.296.5573.1655
    • The phosphoinositide 3-kinase pathway. Cantley LC, Science 2002 296 5573 1655 7 10.1126/science.296.5573.1655 12040186 (Pubitemid 34579158)
    • (2002) Science , vol.296 , Issue.5573 , pp. 1655-1657
    • Cantley, L.C.1
  • 15
    • 77953116018 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase gamma (PI3Kgamma) inhibitors for the treatment of inflammation and autoimmune disease
    • 10.2174/187221310789895603 20017720
    • Phosphoinositide 3-kinase gamma (PI3Kgamma) inhibitors for the treatment of inflammation and autoimmune disease. Venable JD, et al. Recent Pat Inflamm Allergy Drug Discov 2010 4 1 1 15 10.2174/187221310789895603 20017720
    • (2010) Recent Pat Inflamm Allergy Drug Discov , vol.4 , Issue.1 , pp. 1-15
    • Venable, J.D.1
  • 16
    • 0029090212 scopus 로고
    • Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase
    • 10.1126/science.7624799 7624799
    • Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase. Stoyanov B, et al. Science 1995 269 5224 690 3 10.1126/science.7624799 7624799
    • (1995) Science , vol.269 , Issue.5224 , pp. 690-3
    • Stoyanov, B.1
  • 17
    • 65249157965 scopus 로고    scopus 로고
    • Regulation of p110delta PI 3-kinase gene expression
    • 19357769
    • Regulation of p110delta PI 3-kinase gene expression. Kok K, et al. PLoS One 2009 4 4 5145. 19357769
    • (2009) PLoS One , vol.4 , Issue.4 , pp. 55145
    • Kok, K.1
  • 18
  • 19
    • 33847239467 scopus 로고    scopus 로고
    • PI3K delta and PI3K gamma: Partners in crime in inflammation in rheumatoid arthritis and beyond?
    • 10.1038/nri2036 17290298
    • PI3K delta and PI3K gamma: partners in crime in inflammation in rheumatoid arthritis and beyond? Rommel C, Camps M, Ji H, Nat Rev Immunol 2007 7 3 191 201 10.1038/nri2036 17290298
    • (2007) Nat Rev Immunol , vol.7 , Issue.3 , pp. 191-201
    • Rommel, C.1    Camps, M.2    Ji, H.3
  • 22
    • 0037629646 scopus 로고    scopus 로고
    • PI3K and negative regulation of TLR signaling
    • DOI 10.1016/S1471-4906(03)00139-X
    • PI3K and negative regulation of TLR signaling. Fukao T, Koyasu S, Trends Immunol 2003 24 7 358 63 10.1016/S1471-4906(03)00139-X 12860525 (Pubitemid 36830961)
    • (2003) Trends in Immunology , vol.24 , Issue.7 , pp. 358-363
    • Fukao, T.1    Koyasu, S.2
  • 23
    • 0037199972 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells
    • DOI 10.1074/jbc.M203298200
    • The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells. Guha M, Mackman N, J Biol Chem 2002 277 35 32124 32 10.1074/jbc.M203298200 12052830 (Pubitemid 34969025)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.35 , pp. 32124-32132
    • Guha, M.1    Mackman, N.2
  • 25
    • 0037352702 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase is involved in Toll-like receptor 4-mediated cytokine expression in mouse macrophages
    • DOI 10.1002/eji.200323376
    • Phosphatidylinositol 3-kinase is involved in Toll-like receptor 4-mediated cytokine expression in mouse macrophages. Ojaniemi M, et al. Eur J Immunol 2003 33 3 597 605 10.1002/eji.200323376 12616480 (Pubitemid 36367663)
    • (2003) European Journal of Immunology , vol.33 , Issue.3 , pp. 597-605
    • Ojaniemi, M.1    Glumoff, V.2    Harju, K.3    Liljeroos, M.4    Vuori, K.5    Hallman, M.6
  • 26
    • 0028822281 scopus 로고
    • Suppression of lipopolysaccharide-induced tumor necrosis factor-alpha generation from human peripheral blood monocytes by inhibitors of phosphodiesterase 4: Interaction with stimulants of adenylyl cyclase
    • 7476903
    • Suppression of lipopolysaccharide-induced tumor necrosis factor-alpha generation from human peripheral blood monocytes by inhibitors of phosphodiesterase 4: interaction with stimulants of adenylyl cyclase. Seldon PM, et al. Mol Pharmacol 1995 48 4 747 57 7476903
    • (1995) Mol Pharmacol , vol.48 , Issue.4 , pp. 747-57
    • Seldon, P.M.1
  • 27
    • 0142165694 scopus 로고    scopus 로고
    • Cigarette smoke triggers macrophage adhesion and activation: Role of lipid peroxidation products and scavenger receptor
    • DOI 10.1016/S0891-5849(03)00390-3
    • Cigarette smoke triggers macrophage adhesion and activation: role of lipid peroxidation products and scavenger receptor. Kirkham PA, et al. Free Radic Biol Med 2003 35 7 697 710 10.1016/S0891-5849(03)00390-3 14583334 (Pubitemid 37329473)
    • (2003) Free Radical Biology and Medicine , vol.35 , Issue.7 , pp. 697-710
    • Kirkham, P.A.1    Spooner, G.2    Ffoulkes-Jones, C.3    Calvez, R.4
  • 28
    • 0024267782 scopus 로고
    • Differential sensitivity of α(o) and α(i) to ADP-ribosylation by pertussis toxin in the intact cultured embryonic chick ventricular myocyte. Relationship to the role of G proteins in the coupling of muscarinic cholinergic receptors to inhibition of adenylate cyclase activity
    • DOI 10.1016/0006-2952(88)90671-5
    • Differential sensitivity of alpha o and alpha i to ADP-ribosylation by pertussis toxin in the intact cultured embryonic chick ventricular myocyte. Relationship to the role of G proteins in the coupling of muscarinic cholinergic receptors to inhibition of adenylate cyclase activity. Liang BT, Galper JB, Biochem Pharmacol 1988 37 23 4549 55 10.1016/0006-2952(88)90671-5 3144283 (Pubitemid 19003815)
    • (1988) Biochemical Pharmacology , vol.37 , Issue.23 , pp. 4549-4555
    • Liang, B.T.1    Galper, J.B.2
  • 29
    • 0025353245 scopus 로고
    • Mastoparan interacts with the carboxyl terminus of the alpha subunit of Gi
    • 2113529
    • Mastoparan interacts with the carboxyl terminus of the alpha subunit of Gi. Weingarten R, et al. J Biol Chem 1990 265 19 11044 9 2113529
    • (1990) J Biol Chem , vol.265 , Issue.19 , pp. 11044-9
    • Weingarten, R.1
  • 30
    • 34547652582 scopus 로고    scopus 로고
    • NADPH oxidase inhibitors: New antihypertensive agents?
    • DOI 10.1097/FJC.0b013e318063e820, PII 0000534420070700000003
    • NADPH oxidase inhibitors: new antihypertensive agents? Williams HC, Griendling KK, J Cardiovasc Pharmacol 2007 50 1 9 16 10.1097/FJC. 0b013e318063e820 17666910 (Pubitemid 47220441)
    • (2007) Journal of Cardiovascular Pharmacology , vol.50 , Issue.1 , pp. 9-16
    • Williams, H.C.1    Griendling, K.K.2
  • 31
    • 0036606913 scopus 로고    scopus 로고
    • Lipopolysaccharide recognition: CD14, TLRs and the LPS-activation cluster
    • DOI 10.1016/S1471-4906(02)02233-0, PII S1471490602022330
    • Lipopolysaccharide recognition: CD14, TLRs and the LPS-activation cluster. Triantafilou M, Triantafilou K, Trends Immunol 2002 23 6 301 4 10.1016/S1471-4906(02)02233-0 12072369 (Pubitemid 34628773)
    • (2002) Trends in Immunology , vol.23 , Issue.6 , pp. 301-304
    • Triantafilou, M.1    Triantafilou, K.2
  • 32
  • 34
    • 0034707049 scopus 로고    scopus 로고
    • G alpha(i) and G alpha(o) are target proteins of reactive oxygen species
    • 10.1038/35044120 11100733
    • G alpha(i) and G alpha(o) are target proteins of reactive oxygen species. Nishida M, et al. Nature 2000 408 6811 492 5 10.1038/35044120 11100733
    • (2000) Nature , vol.408 , Issue.6811 , pp. 492-5
    • Nishida, M.1
  • 35
    • 0032533546 scopus 로고    scopus 로고
    • 2 or heat shock is mediated by phosphoinositide 3-kinase and not by mitogen-activated protein kinase-activated protein kinase-2
    • The activation of protein kinase B by H2O2 or heat shock is mediated by phosphoinositide 3-kinase and not by mitogen-activated protein kinase-activated protein kinase-2. Shaw M, Cohen P, Alessi DR, Biochem J 1998 336 Pt 1 241 6 9806907 (Pubitemid 28532583)
    • (1998) Biochemical Journal , vol.336 , Issue.1 , pp. 241-246
    • Shaw, M.1    Cohen, P.2    Alessi, D.R.3


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