Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation

Blood

Volumn 115, Issue 23, 2010, Pages 4742-4749

  Krawczyk, Connie M ^a,h   Holowka, Thomas ^a   Sun, Jie ^a,i   Blagih, Julianna ^b,c   Amiel, Eyal ^d   DeBerardinis, Ralph J ^e   Cross, Justin R ^f   Jung, Euihye ^a   Thompson, Craig B ^f,g   Jones, Russell G ^b,c   Pearce, Edward J ^a,d  

^a UNIVERSITY OF PENNSYLVANIA SCHOOL OF VETERINARY MEDICINE   (United States)

^b MCGILL UNIVERSITY   (Canada)

^c MCGILL UNIVERSITY   (Canada)

^d TRUDEAU INSTITUTE   (United States)

^e UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^f UNIVERSITY OF PENNSYLVANIA   (United States)

^g UNIVERSITY OF PENNSYLVANIA   (United States)

^h MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

ⁱ UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE PHOSPHATE; ADENYLATE KINASE; CD86 ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 23; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR AGONIST;

ANAEROBIC GLYCOLYSIS; ANIMAL EXPERIMENT; ARTICLE; CANCER CELL; CELL ACTIVATION; CELL MATURATION; CELL SURVIVAL; DENDRITIC CELL; ENZYME ACTIVATION; GLYCOLYSIS; IMMUNE RESPONSE; INFLAMMATION; LIPID OXIDATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ANIMAL; DRUG ANTAGONISM; GENETICS; IMMUNOLOGY; METABOLISM; MOUSE MUTANT;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; DENDRITIC CELLS; GLYCOLYSIS; INFLAMMATION; INTERLEUKIN-10; MICE; MICE, KNOCKOUT; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS;

EID: 77954735369     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2009-10-249540     Document Type: Article

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