Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells

Nature Cell Biology

Volumn 8, Issue 6, 2006, Pages 623-630

  Ancelin, Katia ^a,b   Lange, Ulrike C ^a   Hajkova, Petra ^a   Schneider, Robert ^c   Bannister, Andrew J ^a   Kouzarides, Tony ^a   Surani, M Azim ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITÉ DE LYON   (France)

^c MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE DERIVATIVE; HISTONE H2A; HISTONE H4; HISTONE METHYLTRANSFERASE; PRMT5 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR BLIMP1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL TRANSPORT; CONTROLLED STUDY; CORRELATION ANALYSIS; DROSOPHILA MELANOGASTER; EMBRYO; EMBRYO CELL; EPIGENETICS; GERM CELL; MOUSE; MOUSE STRAIN; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN METHYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; TRANSCRIPTION REGULATION; UPREGULATION;

ACTIVE TRANSPORT, CELL NUCLEUS; ADENOSINE TRIPHOSPHATASES; AGE FACTORS; ANIMALS; ARGININE; EMBRYO; GENE EXPRESSION REGULATION; GERM CELLS; HISTONES; METHYLATION; MICE; PROTEIN BINDING; PROTEIN METHYLTRANSFERASES; REPRESSOR PROTEINS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

DROSOPHILA MELANOGASTER;

EID: 33744795753     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/ncb1413     Document Type: Article

References (30)

1. Ohinata, Y. et al. Blimp1 is a critical determinant of the germ cell lineage in mice. Nature 436, 207-213 (2005).
2. Vincent, S. D. et al. The zinc finger transcriptional repressor Blimp1/ Prdm1 is dispensable for early axis formation but is required for specification of primordial germ cells in the mouse. Development 132, 1315-1325 (2005).
3. Yu, J., Angelin-Duclos, C., Greenwood, J., Liao, J. & Calame, K. Transcriptional repression by blimp-1 (PRDI-BF1) involves recruitment of histone deacetylase. Mol. Cell. Biol. 20, 2592-2603 (2000).
4. Gyory I., Wu, J., Fejer, G., Seto, E. & Wright, K. L. PRDI-BF1 recruits the histone H3 methyltransferase G9a in transcriptional silencing. Nature Immunol. 5, 299-308 (2004).
5. Anne, J. & Mechler, B. M. Valois, a component of the nuage and pole plasm, is involved in assembly of these structures, and binds to Tudor and the methyltransferase Capsuleen. Development 132, 2167-2177 (2005).
6. Hajkova, P. et al. Epigenetic reprogramming in mouse primordial germ cells. Mach. Dev. 117, 15-23 (2002).
7. Surani, M. A. et al. Mechanism of mouse germ cell specification: A genetic program regulating epigenetic reprogramming. Cold Spring Herb. Symp. Quant. Biol. 69, 1-9 (2004).
8. Ginsburg, M., Snow, M. H. & McLaren, A. Primordial germ cells in the mouse embryo during gastrulation. Development 110, 521-528 (1990).
9. Lachner,. M., O'Sullivan, R. J. & Jenuwein, T. An epigenetic road map for histone lysine methylation. J. Cell Sci. 116, 2117-2124 (2003).
10. Erhardt, S. et al. Consequences of the depletion of zygotic and embryonic enhancer of zeste 2 during preimplantation mouse development. Development 130, 4235-4248 (2003).
11. Tachibana, M. et al. G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis. Genes Dev. 16, 1779-1791 (2002).
12. Shaffer, A. L. et al. Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program. Immunity 17, 51-62 (2002).
13. Shapiro-Shelef, M. et al. Blimp-1 is required for the formation of immunoglobulin secreting plasma cells and pre-plasma memory B cells. Immunity 19, 607-620 (2003).
14. Ren, B., Chee, K. J., Kim, T. H. & Maniatis, T. PRDI-BF1-Blimp-1 repression is mediated by corepressors of the Groucho family of proteins. Genes Dev. 13, 125-137 (1999).
15. Rea, S. et al. Regulation of chromatin structure by site-specific histone H3 methyltransferases. Nature 406, 593-599 (2000).
16. Strahl, B. D. et al. Methylation of histone H4 at arginine 3 occurs in vivo and is mediated by the nuclear receptor coactivator PRMT1. Curr. Biol. 11, 996-1000 (2001).
17. Wang, H. et al. Methylation of histone H4 at arginine 3 facilitating transcriptional activation by nuclear hormone receptor. Science 293, 853-857 (2001).
18. Pal, S., Vishwanath, S. N., Erdjument-Bromage, H., Tempst, P. & Sif, S. Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes. Mol. Cell. Biol. 24, 9630-9645 (2004).
19. Bedford, M. T. & Richard, S. Arginine methylation an emerging regulator of protein function. Mol. Cell 18, 263-272 (2005).
20. Wang, Y. et al. Human PAD4 regulates histone arginine methylation levels via demethylimination. Science 306, 279-283 (2004).
21. Seki, Y. et al. Extensive and orderly reprogramming of genome-wide chromatin modifications associated with specification and early development of germ cells in mice. Dev. Biol. 278, 440-458 (2005).
22. Weinmann, A. S., Bartley, S. M., Zhang, T., Zhang, M. Q. & Farnham, P. J. Use of chromatin immunoprecipitation to clone novel E2F target promoters. Mol. Cell. Biol. 21, 6820-6832 (2001).
23. Oberley, M. J., Inman, D. R. & Farnham, P. J. E2F6 negatively regulates BRCA1 in human cancer cells without methylation of histone H3 on lysine 9. J. Biol. Chem. 278, 42466-42476 (2003).
24. Graham, P. L. & Kimble, J. The mog-1 gene is required for the switch from spermatogenesis to oogenesis in Caenorhabditis elegans. Genetics 133, 919-931 (1993).
25. Kuo, T. C. & Calame, K. L. B lymphocyte-induced maturation protein (Blimp)-1, IFN regulatory factor (IRF)-1, and IRF-2 can bind to the same regulatory sites. J. Immunol. 173, 5556-5563 (2004).
26. Fabbrizio, E. et al. Negative regulation of transcription by the type II arginine methyltransferase PRMT5. EMBO Rep. 3, 641-645 (2002).
27. Sarmento, O. F. et al. Dynamic alterations of specific histone modifications during early murine development. J. Cell Sci. 117, 4449-4459 (2004).
28. Bannister, A. J. et al. Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain. Nature 410, 120-124 (2001).
29. Cote, J. & Richard, S. Tudor domains bind symmetrical dimethylated arginines. J. Biol. Chem. 13, 13 (2005).
30. Saitou, M., Barton, S. C. & Surani, M. A. A molecular programme for the specification of germ cell fate in mice. Nature 418, 293-300 (2002).