MLL protects CpG clusters from methylation within the Hoxa9 gene, maintaining transcript expression

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 21, 2008, Pages 7517-7522

  Erfurth, Frank E ^a   Popovic, Relja ^a   Grembecka, Jolanta ^c   Cierpicki, Tomasz ^c   Theisler, Catherine ^a   Xia, Zhen Biao ^a   Stuart, Tara ^a   Diaz, Manuel O ^a,b   Bushweller, John H ^b   Zeleznik Le, Nancy J ^a,b,d  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

^b LOYOLA UNIVERSITY CHICAGO   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

^d LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Homeodomain; Leukemia; Maintenance

Indexed keywords

DNA BINDING PROTEIN; DNA METHYLTRANSFERASE; HOX PROTEIN; HOXA8 PROTEIN; MIXED LINEAGE LEUKEMIA PROTEIN; SHORT HAIRPIN RNA; HOMEOBOX PROTEIN HOXA9; HOMEODOMAIN PROTEIN;

ARTICLE; BINDING AFFINITY; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CPG ISLAND; DNA BINDING; DNA METHYLATION; GENE CLUSTER; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE LOCUS; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; ISOTHERMAL TITRATION CALORIMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; REAL TIME POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION; ANIMAL; CELL LINE; GENETICS; METABOLISM;

ANIMALS; CELL LINE; CPG ISLANDS; DNA METHYLATION; GENE EXPRESSION REGULATION; HOMEODOMAIN PROTEINS; HUMANS; MICE; MYELOID-LYMPHOID LEUKEMIA PROTEIN; TRANSCRIPTION, GENETIC;

EID: 44949221144     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0800090105     Document Type: Article

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